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aspirin and Glomerulonephritis, Membranoproliferative

aspirin has been researched along with Glomerulonephritis, Membranoproliferative in 10 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Glomerulonephritis, Membranoproliferative: Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN.

Research Excerpts

ExcerptRelevanceReference
" This study investigates the influence of aspirin plus dipyridamole on proteinuria and renal function in nephrotic MPGN patients with moderately reduced glomerular filtration rate."9.07Effect of aspirin and dipyridamole on proteinuria in idiopathic membranoproliferative glomerulonephritis: a multicentre prospective clinical trial. Collaborative Glomerulonephritis Therapy Study Group (CGTS) ( Böhler, J; Braun, N; Grupp, C; Heering, P; Schollmeyer, P; Zäuner, I, 1994)
"They found that in the course of treatment proteinuria did not change and glomerular filtration declined insignificantly."5.28[The effect of acetylsalicylic acid and dipyridamole on glomerular filtration and proteinuria in chronic glomerulonephritis]. ( Jáchymová, M; Knotková, V; Nĕmecek, K; Petrů, I, 1990)
" This study investigates the influence of aspirin plus dipyridamole on proteinuria and renal function in nephrotic MPGN patients with moderately reduced glomerular filtration rate."5.07Effect of aspirin and dipyridamole on proteinuria in idiopathic membranoproliferative glomerulonephritis: a multicentre prospective clinical trial. Collaborative Glomerulonephritis Therapy Study Group (CGTS) ( Böhler, J; Braun, N; Grupp, C; Heering, P; Schollmeyer, P; Zäuner, I, 1994)
" This study investigates the effect of acetylsalicylic acid (ASA) combined with dipyridamole on proteinuria and renal function in nephrotic MPGN patients with normal/moderately reduced glomerular filtration rate (GFR)."3.71Effect of acetylsalicylic acid and dipyridamole in primary membranoproliferative glomerulonephritis type I. ( Baştürk, T; Harmankaya, O; Karabiber, N; Obek, A; Oztürk, Y, 2001)
" The dosage of ASA in the majority of works has been about 1,000 mg daily while isolated investigations have shown good effect from doses as low as 60 mg daily."2.38[Acetylsalicylic acid in the treatment of arterial thromboembolytic diseases. 2. Clinical documentation]. ( Faergeman, O; Fasting, H; Husted, SE; Krusell, LR; Nielsen, HK, 1989)
"We enrolled 35 patients with MPGN type 1 who had a normal creatinine clearance at the time of their first renal biopsy and divided them into 2 groups based on clinical status at the time of their most recent examination: 12 patients with normal urine test results and 12 patients with minor urinary abnormalities at the latest observation (group 1) and 7 patients with persistent nephropathy and 4 patients with renal insufficiency (group 2)."1.33Myeloid-related protein 8 expression on macrophages is a useful prognostic marker for renal dysfunction in children with MPGN type 1. ( Hosoya, M; Isome, M; Kawasaki, Y; Suzuki, H; Takahashi, A; Tanji, M, 2005)
"They found that in the course of treatment proteinuria did not change and glomerular filtration declined insignificantly."1.28[The effect of acetylsalicylic acid and dipyridamole on glomerular filtration and proteinuria in chronic glomerulonephritis]. ( Jáchymová, M; Knotková, V; Nĕmecek, K; Petrů, I, 1990)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's4 (40.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dönmez, O1
Durmaz, O1
Harmankaya, O1
Baştürk, T1
Oztürk, Y1
Karabiber, N1
Obek, A1
Kawasaki, Y1
Hosoya, M1
Takahashi, A1
Isome, M1
Tanji, M1
Suzuki, H1
Zäuner, I1
Böhler, J1
Braun, N1
Grupp, C1
Heering, P1
Schollmeyer, P1
Knotková, V3
Nĕmecek, K3
Nikiforova, OV1
Kozlovskaia, NL1
Rogov, VA1
Zozulia, OV1
Miroshnichenko, NG1
Petrů, I2
Jáchymová, M2
Cieslar, P1
Pelèska, J1
Pick, P1
Tomasy, M1
Donadio, JV1
Offord, KP1
Nielsen, HK1
Husted, SE1
Krusell, LR1
Fasting, H1
Faergeman, O1

Reviews

1 review available for aspirin and Glomerulonephritis, Membranoproliferative

ArticleYear
[Acetylsalicylic acid in the treatment of arterial thromboembolytic diseases. 2. Clinical documentation].
    Ugeskrift for laeger, 1989, Jun-19, Volume: 151, Issue:25

    Topics: Aspirin; Cardiac Surgical Procedures; Diabetic Angiopathies; Female; Glomerulonephritis, Membranopro

1989

Trials

1 trial available for aspirin and Glomerulonephritis, Membranoproliferative

ArticleYear
Effect of aspirin and dipyridamole on proteinuria in idiopathic membranoproliferative glomerulonephritis: a multicentre prospective clinical trial. Collaborative Glomerulonephritis Therapy Study Group (CGTS)
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Blood Pressure; Dietary Proteins;

1994

Other Studies

8 other studies available for aspirin and Glomerulonephritis, Membranoproliferative

ArticleYear
Calcinosis cutis universalis with pediatric systemic lupus erythematosus.
    Pediatric nephrology (Berlin, Germany), 2010, Volume: 25, Issue:7

    Topics: Administration, Oral; Antiphospholipid Syndrome; Aspirin; Calcinosis; Child; Cyclosporine; Dermatolo

2010
Effect of acetylsalicylic acid and dipyridamole in primary membranoproliferative glomerulonephritis type I.
    International urology and nephrology, 2001, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Creatinine; Dipyridamole; Drug

2001
Myeloid-related protein 8 expression on macrophages is a useful prognostic marker for renal dysfunction in children with MPGN type 1.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:3

    Topics: Adolescent; Aspirin; Biomarkers; Biopsy; Calgranulin A; Calgranulin B; Child; Creatinine; Cyclophosp

2005
[Present possibilities of treatment of primary chronic glomerulonephritis].
    Vnitrni lekarstvi, 1994, Volume: 40, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Chronic Disease; Cyclophosphamide; Drug Therapy,

1994
[The successful therapy of an exacerbation of mesangioproliferative nephritis during pregnancy].
    Terapevticheskii arkhiv, 1995, Volume: 67, Issue:10

    Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diagnosis, Differ

1995
[The effect of acetylsalicylic acid and dipyridamole on glomerular filtration and proteinuria in chronic glomerulonephritis].
    Vnitrni lekarstvi, 1990, Volume: 36, Issue:4

    Topics: Adult; Aspirin; Chronic Disease; Dipyridamole; Female; Glomerular Filtration Rate; Glomerulonephriti

1990
[Treatment of chronic proliferative glomerulonephritis using acetylsalicylic acid and dipyridamole].
    Casopis lekaru ceskych, 1989, Jun-28, Volume: 128, Issue:26

    Topics: Adult; Aspirin; Chronic Disease; Dipyridamole; Drug Therapy, Combination; Epoprostenol; Female; Glom

1989
Reassessment of treatment results in membranoproliferative glomerulonephritis, with emphasis on life-table analysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1989, Volume: 14, Issue:6

    Topics: Adult; Aspirin; Child; Cyclophosphamide; Dipyridamole; Drug Therapy, Combination; Glomerulonephritis

1989