Page last updated: 2024-10-23

aspirin and Glaucoma

aspirin has been researched along with Glaucoma in 14 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"Two young patients with unimpaired renal and hepatic function were found to have developed metabolic acidosis after treatment for glaucoma and joint pain with a combination of salicylates and carbonic anhydrase inhibitors in normal doses."7.67Metabolic acidosis induced by carbonic anhydrase inhibitors and salicylates in patients with normal renal function. ( Baird, IM; Cowan, RA; Hartnell, GG; Leak, AM; Lowdell, CP, 1984)
"The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract."7.67Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986)
"Inflammation-driven scarring is a major contributor to surgical failure after subconjunctival bleb forming glaucoma surgery."5.72Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery. ( Armstrong, JJ; Hutnik, CML; Liu, H; Vinokurtseva, A, 2022)
" Although the evidence was limited, people with traumatic hyphema who receive aminocaproic acid or tranexamic acid are less likely to experience secondary hemorrhage."5.41Medical interventions for traumatic hyphema. ( Gharaibeh, A; Goldberg, MF; Lindsley, KB; Ng, SM; Scherer, RW; Woreta, FA, 2023)
"Aspirin has been shown to exhibit neuroprotective properties."5.33Therapeutic potentials of aspirin in glaucomatous optic neuropathy. ( Attarzadeh, A; Hosseini, H; Nowroozizadeh, S, 2006)
"To identify the practices of ophthalmologists when undertaking glaucoma surgery on patients concurrently using warfarin or acetylsalicylic acid (aspirin)."3.74Anticoagulation therapy in glaucoma surgery. ( Alwitry, A; King, AJ; Vernon, SA, 2008)
"Two young patients with unimpaired renal and hepatic function were found to have developed metabolic acidosis after treatment for glaucoma and joint pain with a combination of salicylates and carbonic anhydrase inhibitors in normal doses."3.67Metabolic acidosis induced by carbonic anhydrase inhibitors and salicylates in patients with normal renal function. ( Baird, IM; Cowan, RA; Hartnell, GG; Leak, AM; Lowdell, CP, 1984)
"The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract."3.67Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986)
"A 67-year-old woman and a 75-year-old woman taking carbonic anhydrase inhibitors for therapy of glaucoma and high doses of aspirin for therapy of arthritis developed severe acid-base imbalance and salicylate intoxication."3.66Toxicity of combined therapy with carbonic anhydrase inhibitors and aspirin. ( Anderson, CJ; Kaufman, PL; Sturm, RJ, 1978)
"Inflammation-driven scarring is a major contributor to surgical failure after subconjunctival bleb forming glaucoma surgery."1.72Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery. ( Armstrong, JJ; Hutnik, CML; Liu, H; Vinokurtseva, A, 2022)
"Aspirin was associated with a significantly higher risk of hyphaema (P=0."1.34The effect of aspirin and warfarin therapy in trabeculectomy. ( Chadha, V; Chakrabarti, S; Cobb, CJ; Sanders, R, 2007)
"To investigate risk factors for central retinal vein occlusion (CRVO)."1.34Central retinal vein occlusion case-control study. ( Bruè, C; Ferrara, DC; Koizumi, H; Spaide, RF, 2007)
"Aspirin has been shown to exhibit neuroprotective properties."1.33Therapeutic potentials of aspirin in glaucomatous optic neuropathy. ( Attarzadeh, A; Hosseini, H; Nowroozizadeh, S, 2006)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's1 (7.14)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Vinokurtseva, A1
Armstrong, JJ1
Liu, H1
Hutnik, CML1
Arnesen, RA1
Barbour, KK1
Wu, A1
Yozawitz, EG1
Nelson, A1
Wolf, SM1
McGoldrick, PE1
Basma, N1
Grinspan, ZM1
Woreta, FA1
Lindsley, KB1
Gharaibeh, A1
Ng, SM1
Scherer, RW1
Goldberg, MF1
Elgin, U1
Sen, E1
Teke, MY1
Tirhis, H1
Ozturk, F1
Cobb, CJ1
Chakrabarti, S1
Chadha, V1
Sanders, R1
Attarzadeh, A1
Hosseini, H1
Nowroozizadeh, S1
Koizumi, H1
Ferrara, DC1
Bruè, C1
Spaide, RF1
Alwitry, A1
King, AJ1
Vernon, SA1
Slezak, H1
Cowan, RA1
Hartnell, GG1
Lowdell, CP1
Baird, IM1
Leak, AM1
Lindén, C1
Alm, A1
Anderson, CJ1
Kaufman, PL1
Sturm, RJ1
van Heyningen, R1
Harding, JJ1

Reviews

2 reviews available for aspirin and Glaucoma

ArticleYear
Medical interventions for traumatic hyphema.
    The Cochrane database of systematic reviews, 2023, 03-13, Volume: 3

    Topics: Adrenal Cortex Hormones; Aminocaproic Acid; Antifibrinolytic Agents; Aspirin; Glaucoma; Humans; Hyph

2023
Ophthalmology. What you can do to protect your eyes.
    Harvard health letter, 2001, Volume: 26, Issue:12

    Topics: Alcohol Drinking; Aspirin; Eye Injuries; Eye Protective Devices; Fibrinolytic Agents; Glaucoma; Huma

2001

Trials

1 trial available for aspirin and Glaucoma

ArticleYear
Acetylsalicylic acid does not reduce the intraocular pressure variation in ocular hypertension or glaucoma.
    Experimental eye research, 2000, Volume: 70, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method

2000

Other Studies

11 other studies available for aspirin and Glaucoma

ArticleYear
Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery.
    Experimental eye research, 2022, Volume: 225

    Topics: Aspirin; Cell Transdifferentiation; Cells, Cultured; Chromatography, Liquid; Cicatrix; Collagen; Cyt

2022
Multicenter Assessment of Sturge-Weber Syndrome: A Retrospective Study of Variations in Care and Use of Natural History Data.
    Pediatric neurology, 2023, Volume: 138

    Topics: Aspirin; Child; Epilepsy; Female; Glaucoma; Humans; Male; Retrospective Studies; Seizures; Sturge-We

2023
Microtrauma-induced recurrent hyphema and secondary glaucoma associated with chronic acetylsalicylic acid use.
    International ophthalmology, 2012, Volume: 32, Issue:1

    Topics: Administration, Oral; Adult; Angina Pectoris; Antihypertensive Agents; Aspirin; Diagnosis, Different

2012
The effect of aspirin and warfarin therapy in trabeculectomy.
    Eye (London, England), 2007, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Antihypertensive Agents; Aspirin; Blood

2007
Therapeutic potentials of aspirin in glaucomatous optic neuropathy.
    Medical hypotheses, 2006, Volume: 67, Issue:2

    Topics: Aspirin; Glaucoma; Humans; Neuroprotective Agents; Optic Nerve; Optic Nerve Diseases; Prostaglandins

2006
Central retinal vein occlusion case-control study.
    American journal of ophthalmology, 2007, Volume: 144, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Case-Control Studies; Female; Glaucoma; Humans;

2007
Anticoagulation therapy in glaucoma surgery.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2008, Volume: 246, Issue:6

    Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Glaucoma; Humans; International Normalized Ratio; Oph

2008
[Drug-induced eye lesions in the aged].
    Aktuelle Gerontologie, 1983, Volume: 13, Issue:5

    Topics: Aged; Antipsychotic Agents; Aspirin; Cataract; Conjunctival Diseases; Corneal Diseases; Eye Diseases

1983
Metabolic acidosis induced by carbonic anhydrase inhibitors and salicylates in patients with normal renal function.
    British medical journal (Clinical research ed.), 1984, Aug-11, Volume: 289, Issue:6441

    Topics: Acetazolamide; Acidosis; Adult; Arthritis; Aspirin; Carbonic Anhydrase Inhibitors; Child; Dichlorphe

1984
Toxicity of combined therapy with carbonic anhydrase inhibitors and aspirin.
    American journal of ophthalmology, 1978, Volume: 86, Issue:4

    Topics: Acetazolamide; Acid-Base Imbalance; Aged; Arthritis, Rheumatoid; Aspirin; Carbonic Anhydrase Inhibit

1978
Do aspirin-like analgesics protect against cataract? A case-control study.
    Lancet (London, England), 1986, May-17, Volume: 1, Issue:8490

    Topics: Acetaminophen; Aged; Analgesics; Aspirin; Cataract; Diabetes Complications; Epidemiologic Methods; F

1986