aspirin has been researched along with Genetic Predisposition in 145 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although aspirin has been considered a promising agent for prevention of colorectal cancer, recent data suggest a lack of benefit among older individuals." | 9.51 | Aspirin and the Risk of Colorectal Cancer According to Genetic Susceptibility among Older Individuals. ( Bakshi, A; Buchanan, DD; Cao, Y; Carr, PR; Chan, AT; Gibbs, P; Joshi, AD; Lacaze, P; Macrae, F; Manning, AK; McNeil, JJ; Orchard, SG; Umar, A; Winship, IM; Zalcberg, JR, 2022) |
| "We investigated whether CYP2C9 genotype was associated with risk of colorectal adenoma and/or modified associations with aspirin treatment or cigarette smoking in a cohort of 928 participants in a randomized trial of aspirin chemoprevention." | 9.17 | CYP2C9 variants increase risk of colorectal adenoma recurrence and modify associations with smoking but not aspirin treatment. ( Ahnen, DJ; Baron, JA; Barry, EL; Bresalier, RS; Makar, KW; McKeown-Eyssen, GE; Mott, LA; Poole, EM; Sandler, RS; Ulrich, CM, 2013) |
| "We have reported that in patients with chronic idiopathic urticaria (CIU) who reacted adversely to aspirin, the frequency of the (-444)C allele of the leukotriene C(4) synthase gene (LTC4S) was higher than in patients who tolerated aspirin well." | 9.12 | Familial aggregation of aspirin-induced urticaria and leukotriene C synthase allelic variant. ( Mastalerz, L; Rybarczyk, H; Sanak, M; Setkowicz, M; Szczeklik, A, 2006) |
| "Defining novel molecular mechanisms pertinent to aspirin chemoprevention of breast cancer (BC) and to explain controversial epidemiological results in this regard." | 8.93 | Trinucleotide repeat expansions in human breast cancer-susceptibility genes: relevant targets for aspirin chemoprevention? ( Altinoz, MA; Tunalı, NE, 2016) |
| "Further data from the Aspirin in Reducing Events in the Elderly (ASPREE) trial heightens the concern regarding aspirin use for colorectal cancer prevention in elderly subjects." | 8.12 | Aspirin for Colorectal Cancer Prevention: Age Matters. ( Shureiqi, I, 2022) |
| "Low-dose aspirin can cause gastric and duodenal ulceration, hereafter called peptic ulcer disease (PUD)." | 8.02 | Genome-Wide association between EYA1 and Aspirin-induced peptic ulceration. ( Bourgeois, S; Carr, DF; Deloukas, P; Esume, C; Jorgensen, AL; Morris, AP; Musumba, CO; Penrose, A; Pirmohamed, M; Pritchard, DM; Zhang, JE, 2021) |
| "The authors hypothesized that epigenetic changes may help to clarify the underlying biologic mechanism linking aspirin use to breast cancer prognosis." | 7.91 | Prediagnosis aspirin use, DNA methylation, and mortality after breast cancer: A population-based study. ( Bradshaw, PT; Chen, J; Cho, YH; Gammon, MD; McCullough, LE; Neugut, AI; Santella, RM; Teitelbaum, SL; Terry, MB; Wang, T; White, AJ; Xu, X, 2019) |
| "The use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been associated with reduced breast cancer risk, but it is not known if this association extends to women at familial or genetic risk." | 7.91 | Regular use of aspirin and other non-steroidal anti-inflammatory drugs and breast cancer risk for women at familial or genetic risk: a cohort study. ( Andrulis, IL; Buys, SS; Chung, WK; Cigler, T; Daly, MB; Dite, GS; Friedlander, ML; Giles, GG; Glendon, G; Hopper, JL; John, EM; Kehm, RD; Knight, JA; Kornhauser, N; Liao, Y; MacInnis, RJ; McLachlan, SA; Milne, RL; Nesci, S; Phillips, KA; Southey, MC; Terry, MB; Vahdat, L; Weideman, PC; Zeinomar, N, 2019) |
| "Atrial fibrillation (AF) increases risk of stroke, and although this stroke risk can be ameliorated by warfarin therapy, some patients decline to adhere to warfarin therapy." | 7.81 | Genetic risk for atrial fibrillation could motivate patient adherence to warfarin therapy: a cost effectiveness analysis. ( Arellano, AR; Bare, LA; Devlin, JJ; Louie, JZ; Perez, MV; Shiffman, D, 2015) |
| " In our previous studies, we showed that the TNFA -308A allele is a genetic predisposition factor in a subgroup of aspirin-sensitive (ASA+) CRS patients suffering from nasal polyps (NP) in the Hungarian population." | 7.81 | A conserved linkage group on chromosome 6, the 8.1 ancestral haplotype, is a predisposing factor of chronic rhinosinusitis associated with nasal polyposis in aspirin-sensitive Hungarians. ( Bella, Z; Hirschberg, A; Kadocsa, E; Kemény, L; Kiricsi, Á; Polyánka, H; Révész, M; Szabó, K; Szabó, Z; Széll, M; Vóna, I, 2015) |
| "We aimed to investigate the association of aspirin and/or clopidogrel low response with -455G/A polymorphism of β-fibrinogen in patients with acute coronary syndrome (ACS)." | 7.80 | Impact of -455G/a polymorphism of the β-fibrinogen gene on platelet aggregation in patients with acute coronary syndrome. ( Bakirci, EM; Borekci, A; Kalkan, K; Karakoyun, S; Sevimli, S; Topcu, S; Vançelik, S, 2014) |
| "In our previous study, the SLCO1B1 521TT genotype and the SLCO1B1*1b haplotype were significantly associated with the risk of peptic ulcer in patients taking low-dose aspirin (LDA)." | 7.80 | Single nucleotide polymorphism markers for low-dose aspirin-associated peptic ulcer and ulcer bleeding. ( Fujimura, Y; Fujita, Y; Haruma, K; Murao, T; Nishio, K; Sakakibara, T; Shiotani, A, 2014) |
| "To examine whether the association of aspirin intake with colorectal cancer risk differs according to status of tumor BRAF oncogene mutation." | 7.79 | Aspirin use and risk of colorectal cancer according to BRAF mutation status. ( Chan, AT; Cho, E; Fuchs, CS; Giovannucci, E; Imamura, Y; Jung, S; Kuchiba, A; Liao, X; Lochhead, P; Morikawa, T; Nishihara, R; Ogino, S; Qian, ZR; Spiegelman, D; Wang, M; Yamauchi, M, 2013) |
| "Regular aspirin use reduces the risk for colorectal cancer (CRC), possibly through inhibition of WNT/cadherin-associated protein β1 (CTNNB1 or β-catenin) signaling." | 7.79 | Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations. ( Chan, AT; Freedman, ML; Fuchs, CS; Giovannucci, EL; Hunter, DJ; Imamura, Y; Kraft, P; Kuchiba, A; Morikawa, T; Nan, H; Ogino, S; Suuriniemi, M; Werner, L; Yamauchi, M, 2013) |
| "Aspirin-intolerant asthma (AIA) is an asthma phenotype characterized by the development of bronchoconstriction following ingestion of aspirin." | 7.77 | A possible association of EMID2 polymorphisms with aspirin hypersensitivity in asthma. ( Bae, JS; Cheong, HS; Cho, SH; Choi, IS; Hong, CS; Kim, JH; Kim, MK; Kim, Y; Koh, IS; Lee, JS; Lee, JY; Lee, YW; Park, BL; Park, CS; Park, TJ; Pasaje, CF; Shin, HD, 2011) |
| "To investigate the genetic contribution of adenosine A3 receptor gene (ADORA3) polymorphisms in the pathogenesis of aspirin-induced urticaria (AIU) in a case-control association study in a Korean population." | 7.76 | Functional variability of the adenosine A3 receptor (ADORA3) gene polymorphism in aspirin-induced urticaria. ( Kim, SH; Kim, YK; Nam, EJ; Park, HS; Ye, YM, 2010) |
| "Aspirin affects interleukin-4 (IL-4) synthesis; however, the genetic role of IL-4 has not been evaluated in asthmatics with aspirin hypersensitivity." | 7.76 | Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity. ( Cho, SH; Choi, BW; Choi, IS; Chung, IY; Hong, CS; Jang, AS; Kang, JH; Kim, BS; Kim, MK; Lee, JY; Lee, YW; Park, BL; Park, CS; Park, HS; Park, JS; Park, SM; Shin, HD; Uh, ST; Uhm, TG, 2010) |
| "Aspirin-intolerant asthma (AIA) is a rare condition that is characterized by the development of bronchoconstriction in asthmatic patients after ingestion of non-steroidal anti-inflammatory drugs including aspirin." | 7.76 | Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma. ( Bae, JS; Cheong, HS; Cho, SH; Choi, BW; Choi, IS; Choi, JS; Jang, AS; Kim, JH; Kim, MK; Kim, YH; Park, BL; Park, CS; Park, JS; Shin, HD; Uh, ST, 2010) |
| "Among the patients with asthma, polymorphism at -1082A/G was significantly associated with the phenotype of aspirin-intolerant asthma, AIA (P = 0." | 7.75 | Combined effect of IL-10 and TGF-beta1 promoter polymorphisms as a risk factor for aspirin-intolerant asthma and rhinosinusitis. ( Cho, BY; Kim, SH; Lee, HN; Park, HS; Yang, EM; Ye, YM, 2009) |
| " This study aimed to examine effects of corpus atrophy and the genotypes of genes related to peptic ulcer, including IL-1beta, on risk of aspirin ulcer." | 7.75 | The preventive factors for aspirin-induced peptic ulcer: aspirin ulcer and corpus atrophy. ( Fujita, M; Haruma, K; Hata, J; Imamura, H; Kamada, T; Nishi, R; Sakakibara, T; Shiotani, A; Tarumi, K; Yamanaka, Y, 2009) |
| "Aspirin-intolerant asthma (AIA) is a subtype of asthma induced by non-steroidal anti-inflammatory drugs and characterized by an aggressive mucosal inflammation of the lower airway (asthma) and the upper airways (rhinitis and nasal polyp)." | 7.75 | Gene-expression profiles in human nasal polyp tissues and identification of genetic susceptibility in aspirin-intolerant asthma. ( Hasegawa, T; Hasegawa, Y; Inoue, H; Inoue, I; Kurono, Y; Matsune, S; Sano, Y; Sekigawa, T; Tajima, A, 2009) |
| "We sought to examine whether NLRP3 polymorphisms are associated with susceptibility to food allergy, food-induced anaphylaxis, and aspirin-induced asthma (AIA)." | 7.75 | Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma. ( Doi, S; Ebisawa, M; Enomoto, T; Fujita, K; Harada, M; Higashi, N; Hirota, T; Hitomi, Y; Imai, T; Kohno, Y; Komata, T; Miyatake, A; Nakamura, Y; Sakashita, M; Shimojo, N; Suzuki, Y; Tamari, M; Taniguchi, M; Tomikawa, M, 2009) |
| " We hypothesized that the three subsets of the FCER1 gene may play a role in the development of the aspirin-intolerant asthma (AIA) phenotype and analyzed these genetic polymorphisms in association with clinical parameters in AIA patients." | 7.74 | Association of three sets of high-affinity IgE receptor (FcepsilonR1) polymorphisms with aspirin-intolerant asthma. ( Cho, BY; Hur, GY; Kim, SH; Palikhe, NS; Park, HS; Ye, YM, 2008) |
| "The contribution of genetic factors to aspirin treatment failure (ATF) for secondary prevention is not settled in patients with ischemic stroke." | 7.74 | The BC genotype of the VNTR polymorphism of platelet glycoprotein Ibalpha is overrepresented in patients with recurrent stroke regardless of aspirin therapy. ( Amaro, S; Cervera, A; Chamorro, A; Obach, V; Reverter, JC; Tàssies, D, 2007) |
| "Aspirin-intolerant asthma (AIA), a major clinical presentation of aspirin hypersensitivity, affects 10% of adult asthmatics." | 7.74 | Association of four-locus gene interaction with aspirin-intolerant asthma in Korean asthmatics. ( Cho, BY; Jeong, HH; Kim, M; Kim, SH; Lee, HY; Lee, J; Park, HS; Wee, K, 2008) |
| "Aspirin-intolerant asthma (AIA) is a subtype of bronchial asthma characterized by development of bronchoconstriction evoked by non-steroidal anti-inflammatory drugs (NSAIDs)." | 7.72 | Polymorphisms in the prostaglandin E2 receptor subtype 2 gene confer susceptibility to aspirin-intolerant asthma: a candidate gene approach. ( Goto, S; Hasegawa, T; Hasegawa, Y; Inoue, H; Inoue, I; Jinnai, N; Kakihara, M; Koshino, T; Nakajima, T; Sakagami, T; Sano, Y; Sekigawa, T; Suzuki, N; Yoshida, K, 2004) |
| "The high prevalence of aspirin intolerance in asthmatics and patients with nasal polyps as well as reports of familial clustering suggest a genetic disposition of this disease." | 7.70 | [Family study of patients with aspirin intolerance and rhinosinusitis]. ( Langenbeck, U; May, A; Wagner, D; Weber, A, 2000) |
| "Although aspirin has been considered a promising agent for prevention of colorectal cancer, recent data suggest a lack of benefit among older individuals." | 5.51 | Aspirin and the Risk of Colorectal Cancer According to Genetic Susceptibility among Older Individuals. ( Bakshi, A; Buchanan, DD; Cao, Y; Carr, PR; Chan, AT; Gibbs, P; Joshi, AD; Lacaze, P; Macrae, F; Manning, AK; McNeil, JJ; Orchard, SG; Umar, A; Winship, IM; Zalcberg, JR, 2022) |
| "Acute inflammation of the vasculature, genetic susceptibility and immunopathogenesis based on a transmittable and infectious origin, are the pathologic events involved in the early inflammatory etiology and progression of this disease." | 5.48 | Melatonin: A hypothesis for Kawasaki disease treatment. ( Gil-Martín, E; López-Muñoz, F; Patiño, P; Ramos, E; Reiter, RJ; Romero, A, 2018) |
| "Associations with breast cancer-specific mortality differed by IA ancestry; SOCS1 rs193779, STAT3 rs1026916, and STAT4 rs11685878 associations were limited to women with low IA ancestry, and associations with JAK1 rs2780890, rs2254002, and rs310245 and STAT1 rs11887698 were observed among women with high IA ancestry." | 5.40 | Genetic variation in the JAK/STAT/SOCS signaling pathway influences breast cancer-specific mortality through interaction with cigarette smoking and use of aspirin/NSAIDs: the Breast Cancer Health Disparities Study. ( Hines, LM; John, EM; Lundgreen, A; Slattery, ML; Stern, MC; Torres-Mejia, G; Wolff, RK, 2014) |
| "Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) protect against colorectal cancer (CRC) and are associated with reduced disease recurrence and improved outcome after primary treatment." | 5.17 | Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer. ( Church, DN; Davidson, B; Domingo, E; Johnstone, E; Kerr, DJ; Midgley, R; Ramamoorthy, R; Sieber, O; Tomlinson, IP; Yanagisawa, Y, 2013) |
| "We investigated whether CYP2C9 genotype was associated with risk of colorectal adenoma and/or modified associations with aspirin treatment or cigarette smoking in a cohort of 928 participants in a randomized trial of aspirin chemoprevention." | 5.17 | CYP2C9 variants increase risk of colorectal adenoma recurrence and modify associations with smoking but not aspirin treatment. ( Ahnen, DJ; Baron, JA; Barry, EL; Bresalier, RS; Makar, KW; McKeown-Eyssen, GE; Mott, LA; Poole, EM; Sandler, RS; Ulrich, CM, 2013) |
| "Clopidogrel is recommended in addition to aspirin to prevent atherothrombotic events in patients with acute coronary syndromes (ACS) and in those undergoing percutaneous coronary intervention (PCI)." | 5.16 | The impact of CYP3A5*1/*3, PIA1/A2 and T744C polymorphisms on clopidogrel and acetylsalicylic acid response variability in Mexican population. ( de la Peña, NC; Isordia-Salas, I; Olalde-Román, MJ; Santiago-Germán, D; Valencia-Sánchez, JS, 2012) |
| "We have reported that in patients with chronic idiopathic urticaria (CIU) who reacted adversely to aspirin, the frequency of the (-444)C allele of the leukotriene C(4) synthase gene (LTC4S) was higher than in patients who tolerated aspirin well." | 5.12 | Familial aggregation of aspirin-induced urticaria and leukotriene C synthase allelic variant. ( Mastalerz, L; Rybarczyk, H; Sanak, M; Setkowicz, M; Szczeklik, A, 2006) |
| " Functional polymorphisms of UGT1A6 (T181A and R184S) and CYP2C9 (R144C and I359L) have been reported to modify the protective effect of aspirin on colorectal adenoma risk." | 5.12 | Genetic variants of UGT1A6 influence risk of colorectal adenoma recurrence. ( Armitage, N; Grainge, M; Houlston, RS; Hubner, RA; Liu, JF; Logan, RF; Muir, KR; Popat, S; Shepherd, V, 2006) |
| "Defining novel molecular mechanisms pertinent to aspirin chemoprevention of breast cancer (BC) and to explain controversial epidemiological results in this regard." | 4.93 | Trinucleotide repeat expansions in human breast cancer-susceptibility genes: relevant targets for aspirin chemoprevention? ( Altinoz, MA; Tunalı, NE, 2016) |
| "Aspirin-induced asthma (AIA) and aspirin-induced urticaria/ angioedema (AIU) are two major aspirin-related allergies." | 4.83 | Genetic markers for differentiating aspirin-hypersensitivity. ( Kim, SH; Park, HS, 2006) |
| " Arachidonic acid metabolites seem to be particularly important in the pathogenesis of nasal polyps in patients with aspirin hypersensitivity rhinosinusitis/asthma syndrome." | 4.82 | Pathogenesis of nasal polyps: an update. ( Kowalski, ML; Lewandowska-Polak, A; Pawliczak, R, 2005) |
| "Further data from the Aspirin in Reducing Events in the Elderly (ASPREE) trial heightens the concern regarding aspirin use for colorectal cancer prevention in elderly subjects." | 4.12 | Aspirin for Colorectal Cancer Prevention: Age Matters. ( Shureiqi, I, 2022) |
| "Low-dose aspirin can cause gastric and duodenal ulceration, hereafter called peptic ulcer disease (PUD)." | 4.02 | Genome-Wide association between EYA1 and Aspirin-induced peptic ulceration. ( Bourgeois, S; Carr, DF; Deloukas, P; Esume, C; Jorgensen, AL; Morris, AP; Musumba, CO; Penrose, A; Pirmohamed, M; Pritchard, DM; Zhang, JE, 2021) |
| "This study involved 306 subjects, referred to the Be'sat hospital in Kurdistan Province, which were divided into three groups, (i) Aspirin Induced Asthma (AIA), (ii) Aspirin Tolerant Asthma (ATA), and (iii) healthy subjects as control." | 3.96 | Association of CYP2C19 and HSP70 Genes Polymorphism with Aspirin- Exacerbated Respiratory Disease in a Kurd Population. ( Abdi, M; Jalili, A; Kalmarzi, RN; Kooti, W; Malik, YS; Nouri, B; Rahmani, MR; Rezaee, MA, 2020) |
| "The authors hypothesized that epigenetic changes may help to clarify the underlying biologic mechanism linking aspirin use to breast cancer prognosis." | 3.91 | Prediagnosis aspirin use, DNA methylation, and mortality after breast cancer: A population-based study. ( Bradshaw, PT; Chen, J; Cho, YH; Gammon, MD; McCullough, LE; Neugut, AI; Santella, RM; Teitelbaum, SL; Terry, MB; Wang, T; White, AJ; Xu, X, 2019) |
| "The use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been associated with reduced breast cancer risk, but it is not known if this association extends to women at familial or genetic risk." | 3.91 | Regular use of aspirin and other non-steroidal anti-inflammatory drugs and breast cancer risk for women at familial or genetic risk: a cohort study. ( Andrulis, IL; Buys, SS; Chung, WK; Cigler, T; Daly, MB; Dite, GS; Friedlander, ML; Giles, GG; Glendon, G; Hopper, JL; John, EM; Kehm, RD; Knight, JA; Kornhauser, N; Liao, Y; MacInnis, RJ; McLachlan, SA; Milne, RL; Nesci, S; Phillips, KA; Southey, MC; Terry, MB; Vahdat, L; Weideman, PC; Zeinomar, N, 2019) |
| "There is a genetic association between polymorphisms of genes involved in the synthesis of proteins related to arachidonic acid metabolism (LTC4S, ALOX5), antigen presentation (HLA), inflammation (IL5, IL17), and aspirin metabolism (CYP2C19)." | 3.85 | Physiopathology and genetics in aspirin-exacerbated respiratory disease. ( Falfán-Valencia, R; Pavón-Romero, GF; Ramírez-Jiménez, F; Roldán-Alvarez, MA; Terán, LM, 2017) |
| "Aspirin-exacerbated respiratory disease (AERD) is an endotype of severe and eosinophilic adult asthma characterized by chronic rhinosinusitis with nasal polyps and hypersensitivity to aspirin and/or nonsteroidal anti-inflammatory drugs." | 3.81 | Dipeptidyl-peptidase 10 as a genetic biomarker for the aspirin-exacerbated respiratory disease phenotype. ( Choi, H; Kim, SH; Park, HS; Ye, YM; Yoon, MG, 2015) |
| "Atrial fibrillation (AF) increases risk of stroke, and although this stroke risk can be ameliorated by warfarin therapy, some patients decline to adhere to warfarin therapy." | 3.81 | Genetic risk for atrial fibrillation could motivate patient adherence to warfarin therapy: a cost effectiveness analysis. ( Arellano, AR; Bare, LA; Devlin, JJ; Louie, JZ; Perez, MV; Shiffman, D, 2015) |
| " In our previous studies, we showed that the TNFA -308A allele is a genetic predisposition factor in a subgroup of aspirin-sensitive (ASA+) CRS patients suffering from nasal polyps (NP) in the Hungarian population." | 3.81 | A conserved linkage group on chromosome 6, the 8.1 ancestral haplotype, is a predisposing factor of chronic rhinosinusitis associated with nasal polyposis in aspirin-sensitive Hungarians. ( Bella, Z; Hirschberg, A; Kadocsa, E; Kemény, L; Kiricsi, Á; Polyánka, H; Révész, M; Szabó, K; Szabó, Z; Széll, M; Vóna, I, 2015) |
| "We aimed to investigate the association of aspirin and/or clopidogrel low response with -455G/A polymorphism of β-fibrinogen in patients with acute coronary syndrome (ACS)." | 3.80 | Impact of -455G/a polymorphism of the β-fibrinogen gene on platelet aggregation in patients with acute coronary syndrome. ( Bakirci, EM; Borekci, A; Kalkan, K; Karakoyun, S; Sevimli, S; Topcu, S; Vançelik, S, 2014) |
| "According to findings of a study in the Journal of the National Cancer Institute, people with a single-nucleotide polymorphism on chromosome 8q24 who regularly use aspirin can cut their risk of colorectal cancer by about half." | 3.80 | Protective effect of aspirin associated with SNP. ( , 2014) |
| "In our previous study, the SLCO1B1 521TT genotype and the SLCO1B1*1b haplotype were significantly associated with the risk of peptic ulcer in patients taking low-dose aspirin (LDA)." | 3.80 | Single nucleotide polymorphism markers for low-dose aspirin-associated peptic ulcer and ulcer bleeding. ( Fujimura, Y; Fujita, Y; Haruma, K; Murao, T; Nishio, K; Sakakibara, T; Shiotani, A, 2014) |
| "The aim of this study was to evaluate the association of PON1 genetic variants with the susceptibility to coronary artery disease (CAD) and with the clinical endpoints in aspirin and clopidogrel (dual antiplatelet therapy)-treated Han Chinese patients with CAD after percutaneous coronary intervention (PCI)." | 3.79 | Association of PON1 genotype and haplotype with susceptibility to coronary artery disease and clinical outcomes in dual antiplatelet-treated Han Chinese patients. ( Chen, JY; Kang, YH; Lai, WH; Lao, HY; Li, XX; Wu, H; Yu, XY; Zhong, SL, 2013) |
| "To examine whether the association of aspirin intake with colorectal cancer risk differs according to status of tumor BRAF oncogene mutation." | 3.79 | Aspirin use and risk of colorectal cancer according to BRAF mutation status. ( Chan, AT; Cho, E; Fuchs, CS; Giovannucci, E; Imamura, Y; Jung, S; Kuchiba, A; Liao, X; Lochhead, P; Morikawa, T; Nishihara, R; Ogino, S; Qian, ZR; Spiegelman, D; Wang, M; Yamauchi, M, 2013) |
| "Regular aspirin use reduces the risk for colorectal cancer (CRC), possibly through inhibition of WNT/cadherin-associated protein β1 (CTNNB1 or β-catenin) signaling." | 3.79 | Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations. ( Chan, AT; Freedman, ML; Fuchs, CS; Giovannucci, EL; Hunter, DJ; Imamura, Y; Kraft, P; Kuchiba, A; Morikawa, T; Nan, H; Ogino, S; Suuriniemi, M; Werner, L; Yamauchi, M, 2013) |
| "Since subepithelial fibrosis and protruded extracellular matrix are among the histological characteristics of polyps, the emilin/multimerin domain-containing protein 2 (EMID2) gene is speculated to be involved in the presence of nasal polyps in asthma and aspirin-hypersensitive patients." | 3.78 | Possible role of EMID2 on nasal polyps pathogenesis in Korean asthma patients. ( Bae, JS; Cheong, HS; Jang, AS; Kim, JH; Park, BL; Park, CS; Pasaje, CF; Shin, HD; Uh, ST, 2012) |
| "The aim of the present study was to develop a diagnostic set of single-nucleotide polymorphisms (SNPs) for discriminating aspirin-exacerbated respiratory disease (AERD) from aspirin-tolerant asthma (ATA) using the genome-wide association study (GWAS) data; the GWAS data were filtered according to p-values and odds ratios (ORs) using PLINK software, and the 10 candidate SNPs most closely associated with AERD were selected, based on 100 AERD and 100 ATA subjects." | 3.78 | A highly sensitive and specific genetic marker to diagnose aspirin-exacerbated respiratory disease using a genome-wide association study. ( Choi, BW; Choi, IS; Kim, MK; Kim, YJ; Park, BL; Park, CS; Park, J; Shin, H; Shin, SW; Uh, ST, 2012) |
| "Aspirin-intolerant asthma (AIA) is an asthma phenotype characterized by the development of bronchoconstriction following ingestion of aspirin." | 3.77 | A possible association of EMID2 polymorphisms with aspirin hypersensitivity in asthma. ( Bae, JS; Cheong, HS; Cho, SH; Choi, IS; Hong, CS; Kim, JH; Kim, MK; Kim, Y; Koh, IS; Lee, JS; Lee, JY; Lee, YW; Park, BL; Park, CS; Park, TJ; Pasaje, CF; Shin, HD, 2011) |
| " To carry out a case-control analysis between AGT and aspirin-induced bronchospasm following treatment with an anti-asthma drug, montelukast (MLK), 38 single nucleotide polymorphisms (SNPs) in AGT were genotyped in 56 AIA cohort." | 3.77 | Association of the variants in AGT gene with modified drug response in Korean aspirin-intolerant asthma patients. ( Bae, JS; Cheong, HS; Kim, JH; Kim, JM; Kim, Y; Lee, JS; Park, BL; Park, CS; Park, JS; Park, TJ; Pasaje, CF; Shin, HD, 2011) |
| "The inability of aspirin (ASA) to adequately suppress platelet aggregation is associated with future risk of coronary artery disease (CAD)." | 3.76 | A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease. ( Becker, DM; Becker, LC; Faraday, N; Hererra-Galeano, JE; Kim, Y; Mantese, VJ; Mathias, RA; Ruczinski, I; Sung, H; Wilson, AF; Yanek, LR, 2010) |
| "To investigate the genetic contribution of adenosine A3 receptor gene (ADORA3) polymorphisms in the pathogenesis of aspirin-induced urticaria (AIU) in a case-control association study in a Korean population." | 3.76 | Functional variability of the adenosine A3 receptor (ADORA3) gene polymorphism in aspirin-induced urticaria. ( Kim, SH; Kim, YK; Nam, EJ; Park, HS; Ye, YM, 2010) |
| "Aspirin affects interleukin-4 (IL-4) synthesis; however, the genetic role of IL-4 has not been evaluated in asthmatics with aspirin hypersensitivity." | 3.76 | Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity. ( Cho, SH; Choi, BW; Choi, IS; Chung, IY; Hong, CS; Jang, AS; Kang, JH; Kim, BS; Kim, MK; Lee, JY; Lee, YW; Park, BL; Park, CS; Park, HS; Park, JS; Park, SM; Shin, HD; Uh, ST; Uhm, TG, 2010) |
| "Aspirin-intolerant asthma (AIA) is a rare condition that is characterized by the development of bronchoconstriction in asthmatic patients after ingestion of non-steroidal anti-inflammatory drugs including aspirin." | 3.76 | Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma. ( Bae, JS; Cheong, HS; Cho, SH; Choi, BW; Choi, IS; Choi, JS; Jang, AS; Kim, JH; Kim, MK; Kim, YH; Park, BL; Park, CS; Park, JS; Shin, HD; Uh, ST, 2010) |
| " We replicated the observation of the Atherosclerosis Risk in Communities Study and observed an interaction of rs20417 with aspirin use on myocardial infarction risk (p for interaction=0." | 3.75 | Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke. ( Bis, JC; Heckbert, SR; Lemaitre, RN; Lumley, TS; Marciante, K; Psaty, BM; Rice, K; Smith, NL; Wiggins, KL, 2009) |
| "To investigate the functional variability of HNMT gene in relation to genetic polymorphisms in patients with aspirin intolerant chronic urticaria (AICU)." | 3.75 | Histamine N-methyltransferase 939A>G polymorphism affects mRNA stability in patients with acetylsalicylic acid-intolerant chronic urticaria. ( Cho, BY; Hur, GY; Kang, YM; Kim, SH; Park, HS; Ye, YM, 2009) |
| "Among the patients with asthma, polymorphism at -1082A/G was significantly associated with the phenotype of aspirin-intolerant asthma, AIA (P = 0." | 3.75 | Combined effect of IL-10 and TGF-beta1 promoter polymorphisms as a risk factor for aspirin-intolerant asthma and rhinosinusitis. ( Cho, BY; Kim, SH; Lee, HN; Park, HS; Yang, EM; Ye, YM, 2009) |
| " This study aimed to examine effects of corpus atrophy and the genotypes of genes related to peptic ulcer, including IL-1beta, on risk of aspirin ulcer." | 3.75 | The preventive factors for aspirin-induced peptic ulcer: aspirin ulcer and corpus atrophy. ( Fujita, M; Haruma, K; Hata, J; Imamura, H; Kamada, T; Nishi, R; Sakakibara, T; Shiotani, A; Tarumi, K; Yamanaka, Y, 2009) |
| "Aspirin-intolerant asthma (AIA) is a subtype of asthma induced by non-steroidal anti-inflammatory drugs and characterized by an aggressive mucosal inflammation of the lower airway (asthma) and the upper airways (rhinitis and nasal polyp)." | 3.75 | Gene-expression profiles in human nasal polyp tissues and identification of genetic susceptibility in aspirin-intolerant asthma. ( Hasegawa, T; Hasegawa, Y; Inoue, H; Inoue, I; Kurono, Y; Matsune, S; Sano, Y; Sekigawa, T; Tajima, A, 2009) |
| "We sought to examine whether NLRP3 polymorphisms are associated with susceptibility to food allergy, food-induced anaphylaxis, and aspirin-induced asthma (AIA)." | 3.75 | Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma. ( Doi, S; Ebisawa, M; Enomoto, T; Fujita, K; Harada, M; Higashi, N; Hirota, T; Hitomi, Y; Imai, T; Kohno, Y; Komata, T; Miyatake, A; Nakamura, Y; Sakashita, M; Shimojo, N; Suzuki, Y; Tamari, M; Taniguchi, M; Tomikawa, M, 2009) |
| "We previously demonstrated that single nucleotide polymorphism (SNP) and haplotypes were associated with aspirin hypersensitivity in asthmatics." | 3.75 | Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization. ( Chang, HS; Choi, IS; Chung, IY; Il Lim, G; Jang, AS; Kim, MK; Park, BL; Park, CS; Park, JS; Park, SM; Park, SW; Rhim, T; Shin, HD; Shin, JA; Uh, ST, 2009) |
| " We hypothesized that the three subsets of the FCER1 gene may play a role in the development of the aspirin-intolerant asthma (AIA) phenotype and analyzed these genetic polymorphisms in association with clinical parameters in AIA patients." | 3.74 | Association of three sets of high-affinity IgE receptor (FcepsilonR1) polymorphisms with aspirin-intolerant asthma. ( Cho, BY; Hur, GY; Kim, SH; Palikhe, NS; Park, HS; Ye, YM, 2008) |
| "The contribution of genetic factors to aspirin treatment failure (ATF) for secondary prevention is not settled in patients with ischemic stroke." | 3.74 | The BC genotype of the VNTR polymorphism of platelet glycoprotein Ibalpha is overrepresented in patients with recurrent stroke regardless of aspirin therapy. ( Amaro, S; Cervera, A; Chamorro, A; Obach, V; Reverter, JC; Tàssies, D, 2007) |
| "Aspirin-intolerant asthma (AIA), a major clinical presentation of aspirin hypersensitivity, affects 10% of adult asthmatics." | 3.74 | Association of four-locus gene interaction with aspirin-intolerant asthma in Korean asthmatics. ( Cho, BY; Jeong, HH; Kim, M; Kim, SH; Lee, HY; Lee, J; Park, HS; Wee, K, 2008) |
| "To evaluate the frequencies of COX-2 SNPs in an Australian Caucasian population, and determine potential associations between common COX-2 promoter SNPs and asthma, asthma severity and aspirin-intolerant asthma (AIA)." | 3.74 | Cyclooxygenase-2 gene polymorphisms in an Australian population: association of the -1195G > A promoter polymorphism with mild asthma. ( Duffy, DL; Horn, J; Kedda, MA; Misso, NL; Shi, J; Thompson, PJ; Welch, MD; Williams, C, 2008) |
| "We studied 137 patients undergoing antiplatelet therapy with clopidogrel and 336 patients with aspirin for the occurrence of neurological events (ischemic stroke and/or carotid revascularization)." | 3.73 | Association of a functional polymorphism in the clopidogrel target receptor gene, P2Y12, and the risk for ischemic cerebrovascular events in patients with peripheral artery disease. ( Amighi, J; Brunner, M; Exner, M; Felber, K; Funk, M; Mannhalter, C; Minar, E; Mlekusch, W; Müller, M; Sabeti, S; Schillinger, M; Ziegler, S, 2005) |
| "We speculated TNF-alpha can be one of candidate gene for aspirin-intolerant asthma (AIA) because TNF-alpha is pro-inflammatory cytokine and known to be increased level in asthmatic airways." | 3.73 | Association of TNF-alpha genetic polymorphism with HLA DPB1*0301. ( Choi, JH; Holloway, JW; Kim, SH; Lee, SK; Park, CS; Park, HS; Ye, YM, 2006) |
| "The nonsteroidal anti-inflammatory drug aspirin and the spice curcumin retard adenoma formation when administered long-term to Apc(Min/+) mice, a model of human familial adenomatous polyposis coli." | 3.72 | Age-related difference in susceptibility of Apc(Min/+) mice towards the chemopreventive efficacy of dietary aspirin and curcumin. ( Clarke, AR; Gescher, A; Perkins, S; Steward, W, 2003) |
| "Aspirin-intolerant asthma (AIA) is a subtype of bronchial asthma characterized by development of bronchoconstriction evoked by non-steroidal anti-inflammatory drugs (NSAIDs)." | 3.72 | Polymorphisms in the prostaglandin E2 receptor subtype 2 gene confer susceptibility to aspirin-intolerant asthma: a candidate gene approach. ( Goto, S; Hasegawa, T; Hasegawa, Y; Inoue, H; Inoue, I; Jinnai, N; Kakihara, M; Koshino, T; Nakajima, T; Sakagami, T; Sano, Y; Sekigawa, T; Suzuki, N; Yoshida, K, 2004) |
| " We hypothesized that this polymorphism, which may result in decreased COX-2 transcription, could be associated with more severe asthma, and/or aspirin-intolerant asthma (AIA)." | 3.72 | A functional polymorphism in the promoter region of the cyclooxygenase-2 gene is not associated with asthma and atopy in an Australian population. ( Duffy, DL; Kedda, MA; Misso, NL; Shi, J; Thompson, PJ, 2004) |
| "The high prevalence of aspirin intolerance in asthmatics and patients with nasal polyps as well as reports of familial clustering suggest a genetic disposition of this disease." | 3.70 | [Family study of patients with aspirin intolerance and rhinosinusitis]. ( Langenbeck, U; May, A; Wagner, D; Weber, A, 2000) |
| "Documented VTE (including deep vein thrombosis or pulmonary embolism) and unprovoked VTE (no recent surgery, trauma, or cancer diagnosis) were prospectively evaluated, secondary end points of the trial." | 2.73 | Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study. ( Buring, JE; Glynn, RJ; Goldhaber, SZ; Ridker, PM; Zee, RY, 2007) |
| "Globally, colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the second leading cause of cancer death." | 2.61 | Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. ( Giovannucci, E; Keum, N, 2019) |
| "The cause of colorectal cancer (CRC) is multifactorial, involving both genetic variants and environmental risk factors." | 2.61 | Gene-environment interactions and colorectal cancer risk: An umbrella review of systematic reviews and meta-analyses of observational studies. ( Campbell, H; Dunlop, MG; Farrington, SM; Ioannidis, JPA; Li, X; Little, J; Montazeri, Z; Theodoratou, E; Timofeeva, M; Yang, T, 2019) |
| "Substantial evidence suggests that genetic predisposition plays a vital role in the physiopathology of this complex disease." | 2.55 | Cardiovascular pharmacogenetics: a promise for genomically-guided therapy and personalized medicine. ( El Amri, H; Zaiou, M, 2017) |
| " Hyporesponsive patients might benefit from different dosing strategies or additional antiplatelet therapies." | 2.44 | Investigating the mechanisms of hyporesponse to antiplatelet approaches. ( Angiolillo, D; Bates, E; Berger, PB; Bhatt, D; Braunwald, E; Cannon, CP; Furman, MI; Gurbel, P; Michelson, AD; Peterson, E; Wiviott, S, 2008) |
| " Chemoprevention of colorectal cancer that involves the long-term use of pharmacological agents as aspirin also seems to be effective." | 2.42 | Is colorectal cancer an avoidable disease nowadays? ( Benamouzig, R, 2004) |
| "The findings of this study suggest that genetic susceptibility to ovarian cancer based on currently identified common genetic variants does not appear to modify the protective association between frequent aspirin use and ovarian cancer risk." | 1.91 | Association of Frequent Aspirin Use With Ovarian Cancer Risk According to Genetic Susceptibility. ( Anton-Culver, H; Berchuck, A; Doherty, JA; Goodman, MT; Harris, HR; Hurwitz, LM; Jordan, SJ; Menon, U; Modugno, F; Moysich, KB; Pearce, CL; Pharoah, PDP; Ramus, SJ; Schildkraut, JM; Shvetsov, YB; Trabert, B; Tworoger, SS; Webb, PM; Wentzensen, N; Wu, AH; Ziogas, A, 2023) |
| "MUTYH carriers have an increased colorectal cancer risk in case-control studies, with loss of heterozygosity (LOH) as the presumed mechanism." | 1.72 | Incident Cancer Risk and Signatures Among Older MUTYH Carriers: Analysis of Population-Based and Genomic Cohorts. ( Chan, AT; Downie, JM; Gala, M; Gibbs, P; Lacaze, P; Lee, M; Macrae, F; Mahady, SE; McNeil, JJ; Murray, AM; Orchard, SG; Riaz, M; Schadt, E; Sebra, RP; Woods, RL; Xie, J, 2022) |
| "Aspirin (82%) was the most commonly used ototoxic drug, followed by loop diuretics (77%) and aminoglycosides (57%)." | 1.62 | Pharmacogenetic screening of A1555G and C1494T mitochondrial mutations and the use of ototoxic drugs among Jordanians. ( Al-Trad, B; Bani-Hmoud, M; Rababa'h, AM; Yehya, A, 2021) |
| "It is well established that long-term use of aspirin can cause gastric mucosal injury." | 1.51 | Increased risk of aspirin-induced gastric mucosal erosion in elderly Chinese men harboring SLCO1B1*1b/*1b while using aspirin and an ACEI or ARB concomitantly. ( Bai, Y; Duan, L; Li, H; Li, M; Li, Y; Liu, H, 2019) |
| " Confounders included gender, age, smoking status, dosage of aspirin and clopidogrel, and BMI." | 1.51 | Two common mutations within CYP2C19 affected platelet aggregation in Chinese patients undergoing PCI: a one-year follow-up study. ( Chen, W; Fu, Y; Li, W; Liu, Z; Tang, Y; Wang, W; Wang, Z; Zhang, X; Zhou, Z, 2019) |
| "A part of familial Hirschsprung disease has genetic factors in common with cerebrovascular disease." | 1.51 | A Unique Recurrent Stroke Case due to Bilateral Vertebral Artery Dissection with Familial Hirschsprung Disease. ( Abe, K; Hishikawa, N; Ohta, Y; Sasaki, R; Sato, K; Takemoto, M; Yamashita, T, 2019) |
| "The aetiology of Crohn's disease is poorly understood." | 1.48 | Gut Barrier Dysfunction-A Primary Defect in Twins with Crohn's Disease Predominantly Caused by Genetic Predisposition. ( Halfvarson, J; Keita, ÅV; Lindqvist, CM; Magana, CDL; Öst, Å; Schoultz, I, 2018) |
| "Acute inflammation of the vasculature, genetic susceptibility and immunopathogenesis based on a transmittable and infectious origin, are the pathologic events involved in the early inflammatory etiology and progression of this disease." | 1.48 | Melatonin: A hypothesis for Kawasaki disease treatment. ( Gil-Martín, E; López-Muñoz, F; Patiño, P; Ramos, E; Reiter, RJ; Romero, A, 2018) |
| "Associations with breast cancer-specific mortality differed by IA ancestry; SOCS1 rs193779, STAT3 rs1026916, and STAT4 rs11685878 associations were limited to women with low IA ancestry, and associations with JAK1 rs2780890, rs2254002, and rs310245 and STAT1 rs11887698 were observed among women with high IA ancestry." | 1.40 | Genetic variation in the JAK/STAT/SOCS signaling pathway influences breast cancer-specific mortality through interaction with cigarette smoking and use of aspirin/NSAIDs: the Breast Cancer Health Disparities Study. ( Hines, LM; John, EM; Lundgreen, A; Slattery, ML; Stern, MC; Torres-Mejia, G; Wolff, RK, 2014) |
| "Lenalidomide has significant antimyeloma activity but it is associated with a significant risk of venous thromboembolism (VTE)." | 1.39 | Clinical and genetic factors associated with venous thromboembolism in myeloma patients treated with lenalidomide-based regimens. ( Bagratuni, T; Dimopoulos, MA; Eleutherakis-Papaiakovou, E; Gavriatopoulou, M; Kanelias, N; Kastritis, E; Kostouros, E; Politou, M; Roussou, M; Terpos, E, 2013) |
| "For both colon and rectal cancer, increasing numbers of risk alleles were associated with increased hazard of death from cancer; the estimated hazard of death for colon cancer for the highest category of risk alleles was 1." | 1.39 | Interleukin genes and associations with colon and rectal cancer risk and overall survival. ( Bondurant, KL; Herrick, JS; Kadlubar, S; Lundgreen, A; Slattery, ML; Wolff, RK, 2013) |
| "Two SNPs in TXNRD3 were associated with rectal cancer (rs11718498 dominant OR 1." | 1.38 | Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer. ( Corcoran, C; Lundgreen, A; Slattery, ML; Welbourn, B; Wolff, RK, 2012) |
| "A treatment with aspirin in the human bronchial epithelial cells increased the mRNA expression level of KIF3A compared to that of the untreated control (P ≤ 0." | 1.37 | KIF3A, a cilia structural gene on chromosome 5q31, and its polymorphisms show an association with aspirin hypersensitivity in asthma. ( Bae, JS; Cha, JY; Cheong, HS; Cho, SH; Choi, IS; Jang, AS; Kim, JH; Kim, MK; Park, BL; Park, CS; Park, JS; Shin, HD; Uh, ST, 2011) |
| "The pregnancy was uneventful and the delivery at term." | 1.36 | Treatment of cobalamin C (cblC) deficiency during pregnancy. ( Brunel-Guitton, C; Costa, T; Lambert, M; Mitchell, GA, 2010) |
| "Migraine and migraine aura status were self-reported." | 1.35 | Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular disease. ( Buring, JE; Kurth, T; Schürks, M; Zee, RY, 2008) |
| "A population-based study of 750 rectal cancer cases with interview and tumor DNA were compared to 1,205 population-based controls." | 1.35 | Tumor markers and rectal cancer: support for an inflammation-related pathway. ( Caan, BJ; Herrick, J; Samowitz, W; Slattery, ML; Wolff, RK, 2009) |
| "Myocardial ischemia is the leading cause of postoperative mortality and morbidity in patients undergoing major vascular surgery." | 1.34 | Platelet activation, myocardial ischemic events and postoperative non-response to aspirin in patients undergoing major vascular surgery. ( Bachoo, P; Brittenden, J; Croal, B; Ford, I; Greaves, M; Hillis, GS; Rajagopalan, S, 2007) |
| "Dyslipidemia is associated with macular exudates and vision loss." | 1.32 | Preventing diabetic retinopathy through control of systemic factors. ( Fong, D; Jain, A; Sarraf, D, 2003) |
| "This case provides further evidence of a genetic predisposition to rheumatic fever and demonstrates the continued value of penicillin in the prophylaxis of acute rheumatic fever." | 1.30 | The prophylaxis of acute rheumatic fever in a pair of monozygotic twins. The public health implications. ( Barton, EN; Denbow, CE; Smikle, MF, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (3.45) | 18.2507 |
| 2000's | 53 (36.55) | 29.6817 |
| 2010's | 76 (52.41) | 24.3611 |
| 2020's | 11 (7.59) | 2.80 |
| Authors | Studies |
|---|---|
| Yehya, A | 1 |
| Al-Trad, B | 1 |
| Bani-Hmoud, M | 1 |
| Rababa'h, AM | 1 |
| Bourgeois, S | 1 |
| Carr, DF | 1 |
| Musumba, CO | 1 |
| Penrose, A | 1 |
| Esume, C | 1 |
| Morris, AP | 1 |
| Jorgensen, AL | 1 |
| Zhang, JE | 1 |
| Pritchard, DM | 1 |
| Deloukas, P | 1 |
| Pirmohamed, M | 1 |
| Wang, A | 1 |
| Meng, X | 1 |
| Tian, X | 1 |
| Johnston, SC | 1 |
| Li, H | 2 |
| Bath, PM | 1 |
| Zuo, Y | 1 |
| Xie, X | 1 |
| Jing, J | 1 |
| Lin, J | 2 |
| Wang, Y | 2 |
| Zhao, X | 1 |
| Li, Z | 1 |
| Jiang, Y | 1 |
| Liu, L | 1 |
| Wang, F | 1 |
| Li, Y | 2 |
| Liu, J | 1 |
| Bakshi, A | 1 |
| Cao, Y | 1 |
| Orchard, SG | 2 |
| Carr, PR | 1 |
| Joshi, AD | 1 |
| Manning, AK | 1 |
| Buchanan, DD | 1 |
| Umar, A | 1 |
| Winship, IM | 1 |
| Gibbs, P | 2 |
| Zalcberg, JR | 1 |
| Macrae, F | 2 |
| McNeil, JJ | 2 |
| Lacaze, P | 3 |
| Chan, AT | 4 |
| Forgerini, M | 1 |
| Urbano, G | 1 |
| De Nadai, TR | 1 |
| Zanelli, CF | 1 |
| Valentini, SR | 1 |
| Mastroianni, PC | 1 |
| Downie, JM | 1 |
| Riaz, M | 1 |
| Xie, J | 1 |
| Lee, M | 1 |
| Mahady, SE | 1 |
| Sebra, RP | 1 |
| Murray, AM | 1 |
| Schadt, E | 1 |
| Woods, RL | 1 |
| Gala, M | 1 |
| Shureiqi, I | 1 |
| Hurwitz, LM | 1 |
| Webb, PM | 1 |
| Jordan, SJ | 1 |
| Doherty, JA | 1 |
| Harris, HR | 1 |
| Goodman, MT | 1 |
| Shvetsov, YB | 1 |
| Modugno, F | 1 |
| Moysich, KB | 1 |
| Schildkraut, JM | 1 |
| Berchuck, A | 1 |
| Anton-Culver, H | 1 |
| Ziogas, A | 1 |
| Menon, U | 1 |
| Ramus, SJ | 1 |
| Wu, AH | 1 |
| Pearce, CL | 1 |
| Wentzensen, N | 1 |
| Tworoger, SS | 1 |
| Pharoah, PDP | 1 |
| Trabert, B | 1 |
| Olson, SL | 1 |
| Murray, ML | 1 |
| Skeik, N | 1 |
| Wang, T | 1 |
| McCullough, LE | 1 |
| White, AJ | 1 |
| Bradshaw, PT | 1 |
| Xu, X | 1 |
| Cho, YH | 1 |
| Terry, MB | 2 |
| Teitelbaum, SL | 1 |
| Neugut, AI | 1 |
| Santella, RM | 1 |
| Chen, J | 1 |
| Gammon, MD | 1 |
| Keum, N | 1 |
| Giovannucci, E | 3 |
| Pandey, CP | 1 |
| Misra, A | 1 |
| Negi, MPS | 1 |
| Kanuri, BN | 1 |
| Chhonker, YS | 1 |
| Bhatta, RS | 1 |
| Narain, VS | 1 |
| Dikshit, M | 1 |
| Duan, L | 1 |
| Bai, Y | 1 |
| Li, M | 1 |
| Liu, H | 1 |
| Tang, B | 1 |
| Lo, HH | 1 |
| Lei, C | 1 |
| U, KI | 1 |
| Hsiao, WW | 1 |
| Guo, X | 1 |
| Bai, J | 1 |
| Wong, VK | 1 |
| Law, BY | 1 |
| Hybar, H | 1 |
| Saki, N | 1 |
| Maleknia, M | 1 |
| Moghaddasi, M | 1 |
| Bordbar, A | 1 |
| Naghavi, M | 1 |
| Groza, I | 1 |
| Matei, D | 1 |
| Tantau, M | 1 |
| Trifa, AP | 1 |
| Crisan, S | 1 |
| Vesa, SC | 1 |
| Bocsan, C | 1 |
| Buzoianu, AD | 1 |
| Acalovschi, M | 1 |
| Winship, I | 1 |
| McNeil, J | 1 |
| Pavón-Romero, GF | 1 |
| Ramírez-Jiménez, F | 1 |
| Roldán-Alvarez, MA | 1 |
| Terán, LM | 1 |
| Falfán-Valencia, R | 1 |
| McCarthy, NS | 1 |
| Vangjeli, C | 1 |
| Surendran, P | 1 |
| Treumann, A | 1 |
| Rooney, C | 1 |
| Ho, E | 1 |
| Sever, P | 1 |
| Thom, S | 1 |
| Hughes, AD | 1 |
| Munroe, PB | 1 |
| Howard, P | 1 |
| Johnson, T | 1 |
| Caulfield, M | 1 |
| Shields, DC | 1 |
| O'Brien, E | 1 |
| Fitzgerald, DJ | 2 |
| Stanton, AV | 1 |
| Keita, ÅV | 1 |
| Lindqvist, CM | 1 |
| Öst, Å | 1 |
| Magana, CDL | 1 |
| Schoultz, I | 1 |
| Halfvarson, J | 1 |
| Wang, Z | 1 |
| Liu, Z | 1 |
| Wang, W | 1 |
| Fu, Y | 1 |
| Chen, W | 1 |
| Li, W | 1 |
| Zhang, X | 1 |
| Tang, Y | 1 |
| Zhou, Z | 1 |
| Ramos, E | 1 |
| Patiño, P | 1 |
| Reiter, RJ | 1 |
| Gil-Martín, E | 1 |
| López-Muñoz, F | 1 |
| Romero, A | 1 |
| Yang, T | 1 |
| Li, X | 1 |
| Montazeri, Z | 1 |
| Little, J | 1 |
| Farrington, SM | 1 |
| Ioannidis, JPA | 1 |
| Dunlop, MG | 1 |
| Campbell, H | 1 |
| Timofeeva, M | 1 |
| Theodoratou, E | 1 |
| Kessler, T | 2 |
| Wolf, B | 1 |
| Eriksson, N | 1 |
| Kofink, D | 1 |
| Mahmoodi, BK | 1 |
| Rai, H | 1 |
| Tragante, V | 1 |
| Åkerblom, A | 1 |
| Becker, RC | 1 |
| Bernlochner, I | 1 |
| Bopp, R | 1 |
| James, S | 1 |
| Katus, HA | 1 |
| Mayer, K | 1 |
| Munz, M | 1 |
| Nordio, F | 1 |
| O'Donoghue, ML | 1 |
| Sager, HB | 1 |
| Sibbing, D | 1 |
| Solakov, L | 1 |
| Storey, RF | 1 |
| Wobst, J | 1 |
| Asselbergs, FW | 1 |
| Byrne, RA | 1 |
| Erdmann, J | 1 |
| Koenig, W | 1 |
| Laugwitz, KL | 1 |
| Ten Berg, JM | 1 |
| Wallentin, L | 1 |
| Kastrati, A | 1 |
| Schunkert, H | 2 |
| Kehm, RD | 1 |
| Hopper, JL | 1 |
| John, EM | 2 |
| Phillips, KA | 1 |
| MacInnis, RJ | 1 |
| Dite, GS | 1 |
| Milne, RL | 1 |
| Liao, Y | 1 |
| Zeinomar, N | 1 |
| Knight, JA | 1 |
| Southey, MC | 1 |
| Vahdat, L | 1 |
| Kornhauser, N | 1 |
| Cigler, T | 1 |
| Chung, WK | 1 |
| Giles, GG | 1 |
| McLachlan, SA | 1 |
| Friedlander, ML | 1 |
| Weideman, PC | 1 |
| Glendon, G | 1 |
| Nesci, S | 1 |
| Andrulis, IL | 1 |
| Buys, SS | 1 |
| Daly, MB | 1 |
| Sato, K | 1 |
| Sasaki, R | 1 |
| Ohta, Y | 1 |
| Takemoto, M | 1 |
| Hishikawa, N | 1 |
| Yamashita, T | 1 |
| Abe, K | 1 |
| Kooti, W | 1 |
| Abdi, M | 1 |
| Malik, YS | 1 |
| Nouri, B | 1 |
| Jalili, A | 1 |
| Rezaee, MA | 1 |
| Rahmani, MR | 1 |
| Kalmarzi, RN | 1 |
| Hall, KT | 1 |
| Buring, JE | 4 |
| Passow, D | 1 |
| Sesso, HD | 1 |
| Zee, RYL | 1 |
| Ridker, PM | 4 |
| Chasman, DI | 1 |
| Kang, YH | 1 |
| Lao, HY | 1 |
| Wu, H | 1 |
| Lai, WH | 1 |
| Li, XX | 1 |
| Yu, XY | 1 |
| Chen, JY | 1 |
| Zhong, SL | 1 |
| Bagratuni, T | 1 |
| Kastritis, E | 1 |
| Politou, M | 1 |
| Roussou, M | 1 |
| Kostouros, E | 1 |
| Gavriatopoulou, M | 1 |
| Eleutherakis-Papaiakovou, E | 1 |
| Kanelias, N | 1 |
| Terpos, E | 1 |
| Dimopoulos, MA | 1 |
| Nishihara, R | 1 |
| Lochhead, P | 1 |
| Kuchiba, A | 2 |
| Jung, S | 1 |
| Yamauchi, M | 2 |
| Liao, X | 1 |
| Imamura, Y | 2 |
| Qian, ZR | 1 |
| Morikawa, T | 2 |
| Wang, M | 1 |
| Spiegelman, D | 1 |
| Cho, E | 1 |
| Fuchs, CS | 2 |
| Ogino, S | 2 |
| Domingo, E | 1 |
| Church, DN | 1 |
| Sieber, O | 1 |
| Ramamoorthy, R | 1 |
| Yanagisawa, Y | 1 |
| Johnstone, E | 1 |
| Davidson, B | 1 |
| Kerr, DJ | 1 |
| Tomlinson, IP | 1 |
| Midgley, R | 1 |
| Sevimli, S | 1 |
| Karakoyun, S | 1 |
| Bakirci, EM | 1 |
| Topcu, S | 1 |
| Kalkan, K | 1 |
| Borekci, A | 1 |
| Vançelik, S | 1 |
| Nan, H | 1 |
| Suuriniemi, M | 1 |
| Werner, L | 1 |
| Hunter, DJ | 2 |
| Kraft, P | 1 |
| Giovannucci, EL | 1 |
| Freedman, ML | 1 |
| Slattery, ML | 5 |
| Lundgreen, A | 4 |
| Hines, LM | 1 |
| Torres-Mejia, G | 1 |
| Wolff, RK | 5 |
| Stern, MC | 1 |
| Shiotani, A | 5 |
| Murao, T | 1 |
| Fujita, Y | 2 |
| Fujimura, Y | 2 |
| Sakakibara, T | 4 |
| Nishio, K | 2 |
| Haruma, K | 4 |
| Kim, SH | 14 |
| Choi, H | 1 |
| Yoon, MG | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Possible Protective Effect of Pentoxifylline Against Chemotherapy Induced Toxicities in Patients With Colorectal Cancer[NCT05590117] | Early Phase 1 | 48 participants (Anticipated) | Interventional | 2022-10-11 | Enrolling by invitation | ||
| Diet obEsity sMoking Epigenetics geneTics biomaRkers Physical Activity: An International Multicenter Case-control Study on Endogenous and Exogenous Risk Factors in Early-onset Colorectal Cancer[NCT05732623] | 2,300 participants (Anticipated) | Observational [Patient Registry] | 2022-12-05 | Recruiting | |||
| Prevention of Females Malignancies in Families With Hereditary Breast Cancer by Personalized Optimization of Se Levels in the Organism.[NCT04014283] | 7,000 participants (Anticipated) | Interventional | 2014-10-31 | Active, not recruiting | |||
| Effects of Pulsatile IV Insulin Delivery on Diabetic Retinopathy[NCT00287651] | Phase 2/Phase 3 | 150 participants (Actual) | Interventional | 2005-11-30 | Terminated (stopped due to Administrative) | ||
| Impact of Folates in the Care of the Male Infertility[NCT01407432] | Phase 3 | 162 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
20 reviews available for aspirin and Genetic Predisposition
| Article | Year |
|---|---|
A Novel Frameshift COL3A1 Variant in Vascular Ehlers-Danlos Syndrome.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Collagen Type III; Ehlers-Danlos Syndrome; | 2019 |
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies.
Topics: Age Factors; Age of Onset; Aspirin; Calcium; Carcinogenesis; Colorectal Neoplasms; Diet; Early Detec | 2019 |
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies.
Topics: Age Factors; Age of Onset; Aspirin; Calcium; Carcinogenesis; Colorectal Neoplasms; Diet; Early Detec | 2019 |
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies.
Topics: Age Factors; Age of Onset; Aspirin; Calcium; Carcinogenesis; Colorectal Neoplasms; Diet; Early Detec | 2019 |
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies.
Topics: Age Factors; Age of Onset; Aspirin; Calcium; Carcinogenesis; Colorectal Neoplasms; Diet; Early Detec | 2019 |
Adjuvant herbal therapy for targeting susceptibility genes to Kawasaki disease: An overview of epidemiology, pathogenesis, diagnosis and pharmacological treatment of Kawasaki disease.
Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Aspirin; Caspase 3; CD40 Antigens; Child; Child, Pr | 2020 |
Aspirin exacerbated respiratory disease (AERD): molecular and cellular diagnostic & prognostic approaches.
Topics: Animals; Aspirin; Disease Progression; Genetic Predisposition to Disease; Humans; Polymorphism, Gene | 2021 |
Gene-environment interactions and colorectal cancer risk: An umbrella review of systematic reviews and meta-analyses of observational studies.
Topics: Aspirin; Chromosomes, Human, Pair 8; Colorectal Neoplasms; Gene-Environment Interaction; Genetic Pre | 2019 |
Trinucleotide repeat expansions in human breast cancer-susceptibility genes: relevant targets for aspirin chemoprevention?
Topics: Aspirin; Breast Neoplasms; Chemoprevention; Female; Genes, Neoplasm; Genetic Predisposition to Disea | 2016 |
Low-Dose Aspirin-Associated Upper and Mid Gastrointestinal Tract Damage and Gene Polymorphism.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Gastrointestinal Tr | 2015 |
Genetic and Epigenetic Components of Aspirin-Exacerbated Respiratory Disease.
Topics: Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Disease Management; Eosinophi | 2016 |
Cardiovascular pharmacogenetics: a promise for genomically-guided therapy and personalized medicine.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Genetic Predisposition to Disease; Genetic Variation; | 2017 |
Pharmacogenomics in aspirin intolerance.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biotransformation; Genetic Predisposition | 2009 |
Aspirin-induced peptic ulcer and genetic polymorphisms.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Cyclooxygenase 1; C | 2010 |
Recent developments in the use of antiplatelet agents to prevent cardiovascular events.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding C | 2011 |
Risk and preventive factors of low-dose aspirin-induced gastroduodenal injuries: a comprehensive review.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Duodena | 2012 |
Aspirin and coronary artery disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Blood Platelets; Clinical Tria | 2004 |
Is colorectal cancer an avoidable disease nowadays?
Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; | 2004 |
Pathogenesis of nasal polyps: an update.
Topics: Aspirin; Bacterial Physiological Phenomena; Cytokines; Eosinophils; Fibroblasts; Fungi; Genetic Pred | 2005 |
Genetic markers for differentiating aspirin-hypersensitivity.
Topics: Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Genetic Ma | 2006 |
Asthma phenotypes.
Topics: Aspirin; Asthma; Genetic Predisposition to Disease; Genotype; Glucocorticoids; Humans; Hypersensitiv | 2007 |
Investigating the mechanisms of hyporesponse to antiplatelet approaches.
Topics: Aspirin; Blood Platelets; Clopidogrel; Drug Resistance; Drug Therapy, Combination; Genetic Predispos | 2008 |
The role of COX-2 in intestinal cancer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibi | 1999 |
13 trials available for aspirin and Genetic Predisposition
| Article | Year |
|---|---|
Bleeding Risk of Dual Antiplatelet Therapy after Minor Stroke or Transient Ischemic Attack.
Topics: Aged; Alleles; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Ge | 2022 |
Aspirin and the Risk of Colorectal Cancer According to Genetic Susceptibility among Older Individuals.
Topics: Aged; Aspirin; Colorectal Neoplasms; Genetic Predisposition to Disease; Humans; Prospective Studies; | 2022 |
Genetic variation at the coronary artery disease risk locus GUCY1A3 modifies cardiovascular disease prevention effects of aspirin.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Coronary Artery Disease; Female; G | 2019 |
Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemotherapy, Adju | 2013 |
Serum Brain-Derived Neurotrophic Factor is Related to Platelet Reactivity but not to Genetic Polymorphisms within BDNF Encoding Gene in Patients with Type 2 Diabetes.
Topics: Aged; Alleles; Aspirin; Blood Platelets; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Type | 2016 |
Association of renin-angiotensin and endothelial nitric oxide synthase gene polymorphisms with blood pressure progression and incident hypertension: prospective cohort study.
Topics: Angiotensinogen; Antioxidants; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Disease Progressi | 2008 |
The impact of CYP3A5*1/*3, PIA1/A2 and T744C polymorphisms on clopidogrel and acetylsalicylic acid response variability in Mexican population.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Comorbidity; Cytochrome P-450 CYP3A; Drug Resistance; | 2012 |
CYP2C9 variants increase risk of colorectal adenoma recurrence and modify associations with smoking but not aspirin treatment.
Topics: Adenoma; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Chemoprevention; Colorectal Neoplasms; Cytoch | 2013 |
Complement factor H Y402H gene polymorphism, C-reactive protein, and risk of incident myocardial infarction, ischaemic stroke, and venous thromboembolism: a nested case-control study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; beta Carotene; Brain Ischemia; C-Reactive Protein; Cardiova | 2006 |
Familial aggregation of aspirin-induced urticaria and leukotriene C synthase allelic variant.
Topics: Adult; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; D | 2006 |
Genetic variants of UGT1A6 influence risk of colorectal adenoma recurrence.
Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Female; Genetic Pre | 2006 |
Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study.
Topics: 3' Untranslated Regions; Activated Protein C Resistance; Adult; Aspirin; Double-Blind Method; Drug A | 2007 |
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; beta Carotene; Case-Control Studies; Coca | 1997 |
112 other studies available for aspirin and Genetic Predisposition
| Article | Year |
|---|---|
Pharmacogenetic screening of A1555G and C1494T mitochondrial mutations and the use of ototoxic drugs among Jordanians.
Topics: Adult; Aminoglycosides; Aspirin; Cross-Sectional Studies; DNA, Mitochondrial; Ear, Inner; Female; Ge | 2021 |
Genome-Wide association between EYA1 and Aspirin-induced peptic ulceration.
Topics: Aged; Aged, 80 and over; Aspirin; Case-Control Studies; Down-Regulation; Endoscopy, Gastrointestinal | 2021 |
VNTR Polymorphism in Intron 4 of the eNOS Gene and the Risk of Gastrointestinal Bleeding: A Case-control Study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Gastrointestinal Hemorrhage; | 2022 |
Incident Cancer Risk and Signatures Among Older MUTYH Carriers: Analysis of Population-Based and Genomic Cohorts.
Topics: Aged; Aspirin; Colorectal Neoplasms; DNA Glycosylases; Female; Genetic Predisposition to Disease; Ge | 2022 |
Aspirin for Colorectal Cancer Prevention: Age Matters.
Topics: Aged; Aspirin; Colorectal Neoplasms; Double-Blind Method; Genetic Predisposition to Disease; Humans | 2022 |
Association of Frequent Aspirin Use With Ovarian Cancer Risk According to Genetic Susceptibility.
Topics: Aged; Aspirin; Carcinoma, Ovarian Epithelial; Female; Genetic Predisposition to Disease; Humans; Log | 2023 |
Prediagnosis aspirin use, DNA methylation, and mortality after breast cancer: A population-based study.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; BRCA1 Protein; Breast Neoplasms; Caus | 2019 |
Aspirin & clopidogrel non-responsiveness & its association with genetic polymorphisms in patients with myocardial infarction.
Topics: Aged; Alleles; Aspirin; CD40 Ligand; Clopidogrel; Cyclooxygenase 1; Cytochrome P-450 Enzyme System; | 2019 |
Increased risk of aspirin-induced gastric mucosal erosion in elderly Chinese men harboring SLCO1B1*1b/*1b while using aspirin and an ACEI or ARB concomitantly.
Topics: Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; | 2019 |
VKORC1-1639 G>A Polymorphism and the Risk of Non-Variceal Upper Gastrointestinal Bleeding.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Cross-Sectional Studie | 2017 |
Penetrance and the Healthy Elderly.
Topics: Aged; Aged, 80 and over; Aspirin; Cohort Studies; Female; Genetic Predisposition to Disease; Genetic | 2017 |
Physiopathology and genetics in aspirin-exacerbated respiratory disease.
Topics: Antigen Presentation; Arachidonic Acid; Aspirin; Asthma, Aspirin-Induced; Genetic Association Studie | 2017 |
Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A
Topics: Aged; Aspirin; Cardiovascular Agents; Cardiovascular Diseases; Carrier Proteins; Contactins; Europe; | 2018 |
Gut Barrier Dysfunction-A Primary Defect in Twins with Crohn's Disease Predominantly Caused by Genetic Predisposition.
Topics: Adult; Aspirin; Chelating Agents; Chromium Radioisotopes; Claudin-5; Crohn Disease; Diagnostic Techn | 2018 |
Two common mutations within CYP2C19 affected platelet aggregation in Chinese patients undergoing PCI: a one-year follow-up study.
Topics: Alleles; Aspirin; Blood Platelets; China; Cytochrome P-450 CYP2C19; Female; Genetic Association Stud | 2019 |
Melatonin: A hypothesis for Kawasaki disease treatment.
Topics: Anti-Inflammatory Agents; Aspirin; Child; Child, Preschool; Communicable Diseases; Genetic Predispos | 2018 |
Association of the coronary artery disease risk gene GUCY1A3 with ischaemic events after coronary intervention.
Topics: Aged; Aged, 80 and over; Aspirin; Clinical Trials as Topic; Clopidogrel; Coronary Artery Disease; Co | 2019 |
Regular use of aspirin and other non-steroidal anti-inflammatory drugs and breast cancer risk for women at familial or genetic risk: a cohort study.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; BRCA1 Protein; Breast Neo | 2019 |
A Unique Recurrent Stroke Case due to Bilateral Vertebral Artery Dissection with Familial Hirschsprung Disease.
Topics: Adult; Aspirin; Cerebral Angiography; Cerebral Infarction; Cilostazol; Diffusion Magnetic Resonance | 2019 |
Association of CYP2C19 and HSP70 Genes Polymorphism with Aspirin- Exacerbated Respiratory Disease in a Kurd Population.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cytochrome P-450 CYP2C1 | 2020 |
Association of PON1 genotype and haplotype with susceptibility to coronary artery disease and clinical outcomes in dual antiplatelet-treated Han Chinese patients.
Topics: Aged; Aryldialkylphosphatase; Asian People; Aspirin; Clopidogrel; Coronary Artery Disease; Female; G | 2013 |
Clinical and genetic factors associated with venous thromboembolism in myeloma patients treated with lenalidomide-based regimens.
Topics: Acenocoumarol; Age Factors; Antineoplastic Agents; Aspirin; Female; Genetic Predisposition to Diseas | 2013 |
Aspirin use and risk of colorectal cancer according to BRAF mutation status.
Topics: Aged; Aspirin; Colorectal Neoplasms; Cyclooxygenase 2; Female; Follow-Up Studies; Genetic Predisposi | 2013 |
Impact of -455G/a polymorphism of the β-fibrinogen gene on platelet aggregation in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Female; Fibrinogen; Genetic Predisposition to Disease | 2014 |
Aspirin protects some hearts better than others. It's in the genes. A biomarker can predict a person's response to this potentially lifesaving medication.
Topics: Aspirin; Blood Platelets; Genetic Markers; Genetic Predisposition to Disease; Heart Diseases; Humans | 2013 |
Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; beta Catenin | 2013 |
Protective effect of aspirin associated with SNP.
Topics: Antineoplastic Agents; Aspirin; Chromosomes, Human, Pair 8; Colorectal Neoplasms; Genetic Predisposi | 2014 |
Genetic variation in the JAK/STAT/SOCS signaling pathway influences breast cancer-specific mortality through interaction with cigarette smoking and use of aspirin/NSAIDs: the Breast Cancer Health Disparities Study.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers, Tumor; Breast; Breast Neo | 2014 |
Single nucleotide polymorphism markers for low-dose aspirin-associated peptic ulcer and ulcer bleeding.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Aspirin; Carbohydrate Sulfotransferases; Female; Genetic Pr | 2014 |
Dipeptidyl-peptidase 10 as a genetic biomarker for the aspirin-exacerbated respiratory disease phenotype.
Topics: Adipokines; Adult; Aspirin; Asthma, Aspirin-Induced; Case-Control Studies; Chitinase-3-Like Protein | 2015 |
Cytochrome P450 CYP 2C19*2 Associated with Adverse 1-Year Cardiovascular Events in Patients with Acute Coronary Syndrome.
Topics: Activation, Metabolic; Acute Coronary Syndrome; Aged; Alleles; Angina Pectoris; Aspirin; Clopidogrel | 2015 |
Lynch Syndrome: AGA Patient Guideline Summary.
Topics: Aspirin; Colonoscopy; Colorectal Neoplasms, Hereditary Nonpolyposis; Decision Support Techniques; Ga | 2015 |
Genetic risk for atrial fibrillation could motivate patient adherence to warfarin therapy: a cost effectiveness analysis.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Cost-Benefit Analysis; Genetic Predisposition to Disea | 2015 |
A conserved linkage group on chromosome 6, the 8.1 ancestral haplotype, is a predisposing factor of chronic rhinosinusitis associated with nasal polyposis in aspirin-sensitive Hungarians.
Topics: Adolescent; Adult; Aged; Alleles; Aspirin; Case-Control Studies; Chromosomes, Human, Pair 6; Chronic | 2015 |
Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.
Topics: Animals; Aspirin; Atrial Fibrillation; Bleeding Time; Carotid Artery Diseases; Case-Control Studies; | 2016 |
Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer.
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Cell Line, Tumor; Colonic Neoplasms; Core Binding | 2016 |
Interaction among COX-2, P2Y1 and GPIIIa gene variants is associated with aspirin resistance and early neurological deterioration in Chinese stroke patients.
Topics: Aged; Asian People; Aspirin; China; Cyclooxygenase 1; Cyclooxygenase 2; Drug Resistance; Female; Gen | 2017 |
A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability.
Topics: Adult; Aged; Aspirin; Black or African American; Coronary Artery Disease; Female; Genetic Predisposi | 2008 |
Association of three sets of high-affinity IgE receptor (FcepsilonR1) polymorphisms with aspirin-intolerant asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Bacterial; Aspirin; Asthma; Bronchial Pr | 2008 |
Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Female; Genetic Predisposition to Disease; Humans; Methylene | 2008 |
The influence of polymorphisms of VKORC1 and CYP2C9 on major gastrointestinal bleeding risk in anticoagulated patients.
Topics: Acenocoumarol; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents | 2008 |
Adenosine deaminase and adenosine receptor polymorphisms in aspirin-intolerant asthma.
Topics: Adenosine Deaminase; Adult; Aspirin; Asthma; Bronchial Provocation Tests; Case-Control Studies; Drug | 2009 |
Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke.
Topics: Adult; Aged; Arachidonate Lipoxygenases; Aspirin; Brain Ischemia; Case-Control Studies; Cyclooxygena | 2009 |
Histamine N-methyltransferase 939A>G polymorphism affects mRNA stability in patients with acetylsalicylic acid-intolerant chronic urticaria.
Topics: Adult; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Case-Control Studies; C | 2009 |
Combined effect of IL-10 and TGF-beta1 promoter polymorphisms as a risk factor for aspirin-intolerant asthma and rhinosinusitis.
Topics: Adult; Alleles; Aspirin; Asthma; Drug Hypersensitivity; Epistasis, Genetic; Female; Gene Frequency; | 2009 |
Routine aspirin or nonsteroidal anti-inflammatory drugs for the primary prevention of colorectal cancer.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Asian People; Aspirin; Colorectal Neoplasms; Genetic Predis | 2009 |
The preventive factors for aspirin-induced peptic ulcer: aspirin ulcer and corpus atrophy.
Topics: Aged; Aspirin; Atrophy; Cyclooxygenase 1; Female; Genetic Predisposition to Disease; Genotype; Human | 2009 |
Tumor markers and rectal cancer: support for an inflammation-related pathway.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Biomarkers, Tumor; Cali | 2009 |
Familial chilblain lupus--a monogenic form of cutaneous lupus erythematosus due to a heterozygous mutation in TREX1.
Topics: Adolescent; Aspirin; Biopsy, Needle; Chronic Disease; Disease Progression; Drug Therapy, Combination | 2009 |
Gene-expression profiles in human nasal polyp tissues and identification of genetic susceptibility in aspirin-intolerant asthma.
Topics: Adult; Aged; Algorithms; Artificial Intelligence; Aspirin; Asthma; Case-Control Studies; Cluster Ana | 2009 |
Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
Topics: Alleles; Anaphylaxis; Aspirin; Carrier Proteins; Child; Child, Preschool; Drug Hypersensitivity; Exo | 2009 |
Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization.
Topics: Aspirin; Asthma; Cell Line; Drug Hypersensitivity; Electrophoretic Mobility Shift Assay; Flow Cytome | 2009 |
Do systemic risk factors impact invasive findings from virtual histology? Insights from the international virtual histology registry.
Topics: Aged; Aspirin; Coronary Artery Bypass; Coronary Artery Disease; Diabetic Angiopathies; Dyslipidemias | 2010 |
Familial Takayasu's arteritis in female siblings.
Topics: Adult; Aorta, Thoracic; Aspirin; Clopidogrel; Family Health; Female; Genetic Predisposition to Disea | 2011 |
A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease.
Topics: Adult; Aspirin; Black or African American; Blood Platelets; Chromosomes, Human, Pair 5; Coronary Art | 2010 |
Functional variability of the adenosine A3 receptor (ADORA3) gene polymorphism in aspirin-induced urticaria.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Asian People; Aspirin; Basophils; Case-Control Studi | 2010 |
Treatment of cobalamin C (cblC) deficiency during pregnancy.
Topics: Amino Acid Metabolism, Inborn Errors; Aspirin; Carnitine; Carrier Proteins; Cells, Cultured; Combine | 2010 |
Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Cell Nucleus; Chromosome Mapping; Drug Tolerance; Female; | 2010 |
KIF3A, a cilia structural gene on chromosome 5q31, and its polymorphisms show an association with aspirin hypersensitivity in asthma.
Topics: Adult; Aged; Aspirin; Asthma, Aspirin-Induced; Bronchi; Chromosomes, Human, Pair 5; Cilia; Drug Hype | 2011 |
Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chromosome Mappin | 2010 |
A possible association of EMID2 polymorphisms with aspirin hypersensitivity in asthma.
Topics: Adolescent; Adult; Aged; Asian People; Aspirin; Asthma; Case-Control Studies; Chromosome Mapping; Co | 2011 |
Aspirin and nonsteroidal anti-inflammatory drug intolerance.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Genetic Predispos | 2010 |
Possible association of SLC22A2 polymorphisms with aspirin-intolerant asthma.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; | 2011 |
Association analysis of thromboxane A synthase 1 gene polymorphisms with aspirin intolerance in asthmatic patients.
Topics: Adolescent; Adult; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin- | 2011 |
Aspirin-exacerbated respiratory disease: is it in our DNA?
Topics: Aspirin; Drug Hypersensitivity; Genetic Predisposition to Disease; Humans; Polymorphism, Single Nucl | 2011 |
Association of the variants in AGT gene with modified drug response in Korean aspirin-intolerant asthma patients.
Topics: Acetates; Adolescent; Adult; Aged; Algorithms; Angiotensinogen; Anti-Asthmatic Agents; Asian People; | 2011 |
Association of FANCC polymorphisms with FEV1 decline in aspirin exacerbated respiratory disease.
Topics: Adolescent; Adult; Aged; Alternative Splicing; Aspirin; Asthma, Aspirin-Induced; Fanconi Anemia Comp | 2012 |
Association analysis of C6 genetic variations and aspirin hypersensitivity in Korean asthmatic patients.
Topics: Adolescent; Adult; Aged; Alleles; Asian People; Aspirin; Asthma, Aspirin-Induced; Case-Control Studi | 2011 |
Genetic association analysis of TAP1 and TAP2 polymorphisms with aspirin exacerbated respiratory disease and its FEV1 decline.
Topics: Adolescent; Adult; Aged; Asian People; Aspirin; Asthma, Aspirin-Induced; ATP Binding Cassette Transp | 2011 |
Polymorphisms of the CYP2C19 gene in Japanese patients with aspirin-exacerbated respiratory disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Asian People; Aspirin; Asthm | 2011 |
Association of interleukin 10 promoter polymorphism at -819 T>C with aspirin-induced urticaria in a Korean population.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; DNA; Genetic Predisposition to Disease; Genotype; | 2011 |
Possible role of EMID2 on nasal polyps pathogenesis in Korean asthma patients.
Topics: Adolescent; Adult; Aged; Antigens, Surface; Asian People; Aspirin; Asthma; Drug Hypersensitivity; Fe | 2012 |
Obstetric complications and pregnancy-related venous thromboembolism: the effect of low-molecular-weight heparin on their prevention in carriers of factor V Leiden or prothrombin G20210A mutation.
Topics: Abortion, Spontaneous; Adult; Aspirin; Case-Control Studies; Drug Therapy, Combination; Factor V; Fe | 2012 |
Single-nucleotide polymorphism rs2290692 in the 3'UTR of ITPKC associated with susceptibility to Kawasaki disease in a Han Chinese population.
Topics: Aspirin; Case-Control Studies; Chi-Square Distribution; Child; Child, Preschool; China; Echocardiogr | 2012 |
Von hippel-lindau disease and erythrocytosis.
Topics: Adrenal Gland Neoplasms; Adult; Anticoagulants; Aspirin; Biomarkers; Biopsy; DNA Mutational Analysis | 2012 |
Potential association of DCBLD2 polymorphisms with fall rates of FEV(1) by aspirin provocation in Korean asthmatics.
Topics: Adolescent; Adult; Aged; Alleles; Asian People; Aspirin; Asthma, Aspirin-Induced; Female; Forced Exp | 2012 |
Oxidative balance and colon and rectal cancer: interaction of lifestyle factors and genes.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Neoplasms; Diet; Female; Gene | 2012 |
Multiple gene polymorphisms predisposing to the prothrombotic state in an adolescent with acute myocardial infarction.
Topics: Adolescent; Anticoagulants; Aspirin; Cholesterol Ester Transfer Proteins; Clopidogrel; Coronary Angi | 2012 |
Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Colonic Neoplas | 2012 |
Interleukin genes and associations with colon and rectal cancer risk and overall survival.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers, Tumor; Body Mass Index; C | 2013 |
A possible association between ZNRD1 and aspirin-induced airway bronchoconstriction in a Korean population.
Topics: Adolescent; Adult; Aged; Asian People; Aspirin; Asthma; Bronchoconstriction; Cohort Studies; DNA-Bin | 2012 |
A highly sensitive and specific genetic marker to diagnose aspirin-exacerbated respiratory disease using a genome-wide association study.
Topics: Adolescent; Adult; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, | 2012 |
Heat shock protein 70 gene polymorphisms in Japanese patients with aspirin-exacerbated respiratory disease.
Topics: Aspirin; Asthma, Aspirin-Induced; Cyclooxygenase 2 Inhibitors; Female; Genetic Predisposition to Dis | 2013 |
Recurrent thromboembolism in a patient with beta-thalassemia major associated with double heterozygosity for factor V R506Q and prothrombin G20210A mutations.
Topics: 3' Untranslated Regions; Activated Protein C Resistance; Adult; Anticoagulants; Aspirin; beta-Thalas | 2002 |
Age-related difference in susceptibility of Apc(Min/+) mice towards the chemopreventive efficacy of dietary aspirin and curcumin.
Topics: Adenoma; Administration, Oral; Aging; Animals; Anticarcinogenic Agents; Aspirin; Curcumin; Female; G | 2003 |
Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 2003 |
Preventing diabetic retinopathy through control of systemic factors.
Topics: Anticoagulants; Aspirin; Diabetic Angiopathies; Diabetic Retinopathy; Disease Progression; Female; G | 2003 |
Polymorphisms in the prostaglandin E2 receptor subtype 2 gene confer susceptibility to aspirin-intolerant asthma: a candidate gene approach.
Topics: Aspirin; Asthma; Electrophoresis, Polyacrylamide Gel; Electrophoretic Mobility Shift Assay; Gene Exp | 2004 |
A functional polymorphism in the promoter region of the cyclooxygenase-2 gene is not associated with asthma and atopy in an Australian population.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxyge | 2004 |
Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Binding Sites; Child; Child, P | 2005 |
Association of a functional polymorphism in the clopidogrel target receptor gene, P2Y12, and the risk for ischemic cerebrovascular events in patients with peripheral artery disease.
Topics: Aged; Alleles; Aspirin; Brain Ischemia; Cerebrovascular Circulation; Clopidogrel; Cohort Studies; Ex | 2005 |
Polymorphisms in genes encoding acetylsalicylic acid metabolizing enzymes are unrelated to upper gastrointestinal health in cardiovascular patients on acetylsalicylic acid.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascula | 2005 |
Treatment of multiple familial trichoepitheliomas with a combination of aspirin and a neutralizing antibody to tumor necrosis factor alpha: A case report and hypothesis of mechanism.
Topics: Adalimumab; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aspirin; Carcinoma; Di | 2006 |
A polymorphism of MS4A2 (- 109T > C) encoding the beta-chain of the high-affinity immunoglobulin E receptor (FcepsilonR1beta) is associated with a susceptibility to aspirin-intolerant asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Bacterial; Aspirin; Asthma; Bronchial Pr | 2006 |
Impact of PlA polymorphism of platelet GP IIb/IIIa receptors on clinical course during long-term LVAD support is independent of type of LVAD.
Topics: Anticoagulants; Antigens, Human Platelet; Aspirin; Clopidogrel; Equipment Design; Genetic Predisposi | 2006 |
Association of TNF-alpha genetic polymorphism with HLA DPB1*0301.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Female; Gene | 2006 |
ADAM33 polymorphisms are associated with aspirin-intolerant asthma in the Japanese population.
Topics: ADAM Proteins; Aged; Anti-Inflammatory Agents, Non-Steroidal; Asian People; Aspirin; Asthma; Drug To | 2007 |
Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1.
Topics: Adult; Arachidonic Acid; Aspirin; beta-Thromboglobulin; Black or African American; Blood Platelets; | 2007 |
Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study.
Topics: Aspirin; Atherosclerosis; Biomarkers; Black or African American; Case-Control Studies; Coronary Dise | 2008 |
Heritability, platelet function, and aspirin: a link established but cause unknown.
Topics: Arachidonic Acid; Aspirin; Black or African American; Blood Platelets; Cardiovascular Diseases; Cycl | 2007 |
The BC genotype of the VNTR polymorphism of platelet glycoprotein Ibalpha is overrepresented in patients with recurrent stroke regardless of aspirin therapy.
Topics: Aged; Aspirin; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Huma | 2007 |
Platelet activation, myocardial ischemic events and postoperative non-response to aspirin in patients undergoing major vascular surgery.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspi | 2007 |
A case-control study of the association between polymorphisms of the endothelial nitric oxide synthase and glycoprotein IIIa genes and upper gastrointestinal bleeding in users of low-dose aspirin.
Topics: Aged; Alcohol Drinking; Aspirin; Case-Control Studies; Female; Gastrointestinal Hemorrhage; Gene Fre | 2008 |
Association of four-locus gene interaction with aspirin-intolerant asthma in Korean asthmatics.
Topics: Adult; Aspirin; Asthma; Female; Genetic Predisposition to Disease; Humans; Korea; Male; Pneumonia; P | 2008 |
The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study.
Topics: Adult; Aspirin; Blood Pressure; Cardiovascular Diseases; Female; Genetic Predisposition to Disease; | 2008 |
Cyclooxygenase-2 gene polymorphisms in an Australian population: association of the -1195G > A promoter polymorphism with mild asthma.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Australia; Case-Control Studies; Cyclooxygenase 2; | 2008 |
[Findings in children with psoriasis].
Topics: Adolescent; Adrenal Cortex Hormones; Anthralin; Anti-Inflammatory Agents; Aspirin; Calcitriol; Child | 1999 |
The prophylaxis of acute rheumatic fever in a pair of monozygotic twins. The public health implications.
Topics: Aspirin; Child; Diseases in Twins; Drug Therapy, Combination; Female; Follow-Up Studies; Genetic Pre | 1999 |
[Family study of patients with aspirin intolerance and rhinosinusitis].
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation T | 2000 |
Resistance to melanoma metastases in mice selected for high acute inflammatory response.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Neoplasm; Antigens, Neoplasm; Aspirin; | 2001 |
Aspirin treatment of postvaccinal hypertrophic osteodystrophy in a weimaraner puppy.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacterial Vaccines; Dog | 2002 |
Asthma and HLA system.
Topics: Alleles; Aspirin; Asthma; Base Sequence; Disease Susceptibility; Genes, Dominant; Genetic Markers; G | 1991 |