aspirin has been researched along with Gastrointestinal Hemorrhage in 1326 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent studies have shown that aspirin consumption may reduce the risk of hepatocellular carcinoma (HCC), but their correlation is still not fully understood." | 9.41 | The relationship between aspirin consumption and hepatocellular carcinoma: a systematic review and meta-analysis. ( Chen, R; Lin, Z; Wang, S; Xu, Y; Yang, Z; Zuo, L, 2023) |
| " Patients with newly diagnosed ischemic stroke who are just about to start Aspirin were assessed for eligibility and inclusion in our trial." | 9.34 | An investigation into the impact of enteric coated of aspirin in patients with newly diagnosed ischemic stroke (ECASIS). ( Abdallah, IM; Ahmed, MS; Ali, M; AlSaud, AE; Danjuma, MI; Elshafei, MN; Imam, Y; Mohamed, MFH; Obeidat, K; Parray, AS; Saeid, R, 2020) |
| "Results show the short-term risk of hemorrhage in treating patients with acute transient ischemic attack (TIA) or minor acute ischemic stroke (AIS) with clopidogrel plus aspirin or aspirin alone." | 9.30 | Risk for Major Hemorrhages in Patients Receiving Clopidogrel and Aspirin Compared With Aspirin Alone After Transient Ischemic Attack or Minor Ischemic Stroke: A Secondary Analysis of the POINT Randomized Clinical Trial. ( Barsan, W; Easton, JD; Elm, JJ; Farrant, M; Johnston, SC; Kim, AS; Lindblad, AS; Palesch, YY; Tillman, H, 2019) |
| "To elucidate the efficacy and safety between aspirin and clopidogrel, a multicenter randomized controlled trial was designed in AF patients with low stroke risk." | 9.24 | Rationale and Design for a Randomized Comparison of Efficacy and Safety between Aspirin and Clopidogrel in Atrial Fibrillation Patients with Low Stroke Risk: CESAC-AF trial. ( Bang, CS; Hong, KS; Hong, MK; Jeong, H; Jung, MH; Kim, CY; Park, SM, 2017) |
| "To assess the impact of prophylactic omeprazole with background dual anti-platelet therapy on patient-reported symptoms of dyspepsia compared to placebo." | 9.20 | The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial. ( Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; McIntosh, AI; Schnitzer, TJ; Vardi, M, 2015) |
| "Little is known about the efficacy of proton pump inhibitors compared with H(2) receptor antagonists in preventing adverse upper gastrointestinal complications in patients with acute coronary syndrome (ACS) or ST elevation myocardial infarction (STEMI) receiving aspirin, clopidogrel, and enoxaparin or thrombolytics." | 9.16 | Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction. ( Chan, K; Chu, WM; Keung, KK; Kng, C; Kwan, A; Lam, KF; Lau, YK; Li, A; Ng, FH; Tunggal, P; Wong, BC, 2012) |
| "Adding clopidogrel to aspirin beyond 4 weeks post PCI is not associated with a significant increase in the overall rate of major or minor bleeding, although it is associated with an increase in major gastrointestinal bleeding in the year after a PCI." | 9.14 | Bleeding risk associated with 1 year of dual antiplatelet therapy after percutaneous coronary intervention: Insights from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial. ( Aronow, HD; Berger, PB; Brennan, DM; Steinhubl, SR; Topol, EJ, 2009) |
| "Little is known about the efficacy of H(2)-receptor antagonists in preventing recurrence of aspirin-related peptic ulcers." | 9.14 | Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions. ( Chan, P; Chu, WM; Kng, C; Kwan, A; Lam, KF; Lau, YK; Ling, YH; Ng, FH; Wong, BC; Wong, SY; Yuen, WC, 2010) |
| "It is uncertain whether aspirin therapy should be continued after endoscopic hemostatic therapy in patients who develop peptic ulcer bleeding while receiving low-dose aspirin." | 9.14 | Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trial. ( Chan, FK; Ching, JY; Chiu, PW; Lau, JY; Lee, YT; Leung, VK; Sung, JJ; Wong, VW; Wu, JC, 2010) |
| " Combined warfarin and aspirin therapy was associated with greater fecal hemoglobin excretion than standard warfarin therapy, suggesting the potential for increased gastrointestinal hemorrhage." | 9.08 | Fecal hemoglobin excretion in elderly patients with atrial fibrillation: combined aspirin and low-dose warfarin vs conventional warfarin therapy. ( Ahlquist, DA; Baker, VS; Blackshear, JL; Ellefson, R; Hart, RG; Holland, A; Koehler, J; Litin, SC, 1996) |
| "We carried out a pilot study in 15 hemodialysis patients with recurrent vascular access thrombosis to examine whether the combination of low dose aspirin (85 mg once daily) and sulfinpyrazone (200 mg three times daily) is safe and effective in the prevention of vascular access thrombosis." | 9.07 | Combined aspirin and sulfinpyrazone in the prevention of recurrent hemodialysis vascular access thrombosis. ( Bauman, JE; Domoto, DT; Joist, JH, 1991) |
| "E 1 (misoprostol) as of SAMe, in the present of acute bleeding gastritis induced by 1300 mg aspirin in a single dose and during 2 hours." | 9.05 | [Prostaglandin E1 (misoprostol) and S-adenosylmethionine in the prevention of hemorrhagic gastritis induced by aspirin in the human. Endoscopic, histologic and histochemical study]. ( Capdepon, E; Finkelstein, D; Laudanno, OM, 1984) |
| " Fourteen patients with rheumatoid arthritis received equivalent therapeutic doses of the antinflammatory drugs aspirin, 4 gm/day, and fenoprofen calcium, 2." | 9.04 | Gastrointestinal blood loss. Effect of aspirin, fenoprofen, and acetaminophen in rheumatoid arthritis as determined by sequential gastroscopy and radioactive fecal markers. ( Craig, RM; Culic, DD; Falk, J; Loebl, DH; Ridolfo, AS; Schmid, FR, 1977) |
| "To determine the effectiveness of naproxen in the treatment of osteoarthritis of the knee joint, a double-blind cross-over study against placebo was carried out on 61 patients." | 9.04 | Double-blind study of Naproxen in osteoarthritis of the knee joint. ( Ito, T; Mori, E; Muroga, T; Nakajima, A; Tanaka, S, 1976) |
| "In a double-blind between-patient study of aspirin and benorylate carried out in 72 outpatients with rheumatoid arthritis, benorylate 4 g twice daily was shown to be an effective analgesic and anti-inflammatory drug, its effects being indistinguishable from those of aspirin 1." | 9.03 | Comparison of aspirin and benorylate in the treatment of rheumatoid arthritis. ( Beales, DL; Burry, HC; Grahame, R, 1972) |
| "Aspirin is indicated for primary and secondary prevention of cardiovascular diseases (CVD) by major guidelines." | 8.95 | Efficacy of aspirin (325 mg) + omeprazole (40 mg) in treating coronary artery disease. ( Bliden, K; Chaudhary, R; Gurbel, PA; Sharma, T; Tantry, U, 2017) |
| "To evaluate the risk for serious bleeding with regular aspirin use in cardiovascular disease (CVD) primary prevention." | 8.93 | Bleeding Risks With Aspirin Use for Primary Prevention in Adults: A Systematic Review for the U.S. Preventive Services Task Force. ( Burda, BU; Evans, CV; Guirguis-Blake, JM; Whitlock, EP; Williams, SB, 2016) |
| "Aspirin and gastric ulcer interaction are used as an example to illustrate this concept, especially the narration of how disease affects drug efficacy." | 8.93 | Drug-disease interactions: narrative review of aspirin in gastric ulcer. ( Nwose, EU; Yee, KC, 2016) |
| "This review highlights practical aspects related to aspirin therapy in cardiovascular diseases, specifically, the benefits and hazards in different clinical settings." | 8.91 | A Balanced View of Efficacy and Safety of Aspirin in Cardiovascular Diseases. ( Brugada, P; Casado-Arroyo, R; Lanas, A, 2015) |
| "Aspirin is widely used for secondary prevention after stroke." | 8.87 | Cilostazol versus aspirin for secondary prevention of vascular events after stroke of arterial origin. ( Husain, MR; Kamal, AK; Khealani, BA; Naqvi, I, 2011) |
| "We compared the efficacy and safety of cilostazol and aspirin in 2,672 Japanese patients with non-cardioembolic ischemic stroke." | 8.86 | [Results of the Cilostazol Stroke Prevention Study II (CSPS II): a randomized controlled trial for the comparison of cilostazol and aspirin in stroke patients]. ( Uchiyama, S, 2010) |
| "A prespecified pooled intent-to-treat analysis of three double-blind randomised comparisons of etoricoxib (60 or 90 mg daily) and diclofenac (150 mg daily) in 34 701 patients with osteoarthritis or rheumatoid arthritis was done for upper gastrointestinal clinical events (bleeding, perforation, obstruction, or ulcer) and the subset of complicated events (perforation, obstruction, witnessed ulcer bleeding, or significant bleeding)." | 8.84 | Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. ( Cannon, CP; Cryer, B; Curtis, SP; Kaur, A; Laine, L, 2007) |
| "According to meta-analysis and the results of the two studies with the highest power, aspirin is effective in primary prevention of coronary heart disease." | 8.82 | [Primary prevention of coronary heart disease with aspirin]. ( Darius, H; Kübler, W, 2005) |
| " Patients with diagnosis codes for ischemic stroke without cardiac disease were included and divided into two groups, those receiving cilostazol and those receiving clopidogrel." | 8.31 | Long-term effectiveness and safety of cilostazol versus clopidogrel in secondary prevention of noncardioembolic ischemic stroke. ( Je, NK; Lee, YJ, 2023) |
| "This retrospective multicenter study provides first data indicating a beneficial effect of aspirin on transplant-free survival after TIPS implantation in patients with refractory ascites." | 8.12 | Aspirin improves transplant-free survival after TIPS implantation in patients with refractory ascites: a retrospective multicentre cohort study. ( Bettinger, D; Gu, W; Heinzow, H; Huber, JP; Jansen, C; Köhler, M; Maschmeier, M; Masthoff, M; Meyer, C; Praktiknjo, M; Schindler, P; Schmidt, HH; Schoster, M; Schultheiss, M; Seifert, LL; Seifert, QE; Sturm, L; Trebicka, J; Weller, JF; Wildgruber, M; Wilms, C, 2022) |
| "The US Preventive Services Task Force (USPSTF) is updating its 2016 recommendation on the use of aspirin for the primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC)." | 8.12 | Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force. ( Dehmer, SP; Evans, CV; Guirguis-Blake, JM; Maciosek, MV; O'Keefe, LR; Perdue, LA, 2022) |
| "In the prevalent-user design, there was no significant association between low-dose aspirin and gastric ulcer observed in both cohorts." | 8.12 | Strongly increased risk of gastric and duodenal ulcers among new users of low-dose aspirin: results from two large cohorts with new-user design. ( Brenner, H; Chen, LJ; Holleczek, B; Nguyen, TNM; Schöttker, B; Sha, S, 2022) |
| " Patients aged 80 years or older who received monotherapy with clopidogrel or aspirin following hospitalization for primary acute ischemic stroke between January 1, 2009, and December 31, 2018, were included." | 8.12 | Effectiveness and Safety of Clopidogrel vs Aspirin in Elderly Patients With Ischemic Stroke. ( Huang, HY; Katz, AJ; Lin, FJ; Lin, SY; Sheu, JJ; Wang, CC; Wu, CH, 2022) |
| "Uncertainty remains regarding the impact of enteric-coated aspirin (EC-ASA) on secondary prevention of ischemic stroke compared to plain aspirin (P-ASA)." | 8.12 | The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS) study. ( Abdallah, IM; Abdelmoneim, MS; Akhtar, N; Ali, M; Alsaud, AE; Ayadathil, R; Chandra, P; Danjuma, MI; Elshafei, MN; Imam, Y; Mohamed, MFH; Mohammed, S; Obeidat, K; Parray, A; Saeid, R, 2022) |
| "Aspirin may reduce the risk of chronic hepatitis B (CHB)-related hepatocellular carcinoma (HCC) in patients receiving antiviral treatment." | 8.02 | Aspirin Reduces the Incidence of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B Receiving Oral Nucleos(t)ide Analog. ( Chan, HL; Hui, VW; Lui, GC; Tse, YK; Wong, GL; Wong, VW; Yip, TC, 2021) |
| "More information is needed about the long-term effects of low-dose aspirin (≤160 mg) on incident hepatocellular carcinoma, liver-related mortality, and gastrointestinal bleeding in persons with chronic hepatitis B or hepatitis C virus infection." | 7.96 | Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality. ( Aleman, S; Chan, AT; Chung, RT; Duberg, AS; Ludvigsson, JF; Simon, TG, 2020) |
| " Here, we describe a 3-year-old boy with typical KD who had lower gastrointestinal bleeding caused by rectal ulcers on the third day of aspirin therapy." | 7.96 | A case of rectal ulcers during aspirin therapy in acute Kawasaki disease. ( Han, Y; Hu, C; Yu, Y, 2020) |
| "Aspirin may increase the risk of lower gastrointestinal bleeding (LGIB) from precursors of colorectal cancer (CRC)." | 7.96 | Risk of lower gastrointestinal bleeding and colorectal neoplasms following initiation of low-dose aspirin: a Danish population-based cohort study. ( Erichsen, R; Farkas, DK; Sørensen, HT; Troelsen, FS, 2020) |
| "Comparative gastrointestinal bleeding (GIB) risk between rivaroxaban and low-dose aspirin is unknown in patients with atrial fibrillation (AF)." | 7.96 | Gastrointestinal bleeding risk with rivaroxaban vs aspirin in atrial fibrillation: A multinational study. ( Bell, JS; Chan, EW; Darzins, P; Fanning, L; Ilomaki, J; Lau, WCY; Leung, WK; Li, X; Man, KKC; Mongkhon, P; Wei, L; Wong, ICK, 2020) |
| "Several clinical trials reported that clopidogrel was superior to aspirin in secondary stroke prevention by reducing the risk of major adverse cardiovascular events (MACE)." | 7.91 | Aspirin better than clopidogrel on major adverse cardiovascular events reduction after ischemic stroke: A retrospective nationwide cohort study. ( Chan, L; Chen, YC; Hsu, CY; Hu, CJ; Lin, CL; Muo, CH; Vidyanti, AN; Wu, D, 2019) |
| "To investigate the correlation of tumor necrosis factor α (TNF-α) polymorphisms with upper gastrointestinal bleeding (UGIB) induced by enteric-coated aspirin in coronary heart disease (CHD) patients." | 7.91 | Association between TNF-α polymorphisms and the risk of upper gastrointestinal bleeding induced by aspirin in patients with coronary heart disease. ( Wang, TP, 2019) |
| "Aspirin, commonly used for prevention of cardiovascular and cerebrovascular diseases, is well known to protect against development of colorectal cancer (CRC) but increases risk of gastrointestinal bleeding (GIB)." | 7.88 | Risk of gastrointestinal bleeding and benefit from colorectal cancer reduction from long-term use of low-dose aspirin: A retrospective study of 612 509 patients. ( Chan, FC; Hirai, HW; Sung, JJ; Tsoi, KK, 2018) |
| "Nonvitamin K antagonist oral anticoagulants (NOACs) are now available for the prevention of stroke in patients with atrial fibrillation (AF) as an alternative to vitamin K antagonists (VKA) and aspirin." | 7.85 | Risk of major bleeding and stroke associated with the use of vitamin K antagonists, nonvitamin K antagonist oral anticoagulants and aspirin in patients with atrial fibrillation: a cohort study. ( Bos, J; Burden, AM; de Boer, A; de Vries, F; Gieling, EM; Kramers, C; van den Ham, HA; van Onzenoort, H, 2017) |
| "Evidence indicates that aspirin is effective for the primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC) but also increases the risk for gastrointestinal (GI) and cerebral hemorrhages." | 7.83 | Aspirin for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: A Decision Analysis for the U.S. Preventive Services Task Force. ( Dehmer, SP; Flottemesch, TJ; LaFrance, AB; Maciosek, MV; Whitlock, EP, 2016) |
| "To evaluate the efficacy and safety of aspirin usage for coronary heart disease (CHD) primary prevention in patients with dyslipidemia." | 7.83 | Effects of low-dose aspirin in subjects with dyslipidemia. ( Chen, J; Lou, G; Xia, Y, 2016) |
| "Low-dose aspirin (ASA) is effective for secondary prevention of ischemic stroke but can increase the risks of hemorrhagic stroke, upper gastrointestinal bleeding (UGIB), and dyspepsia." | 7.81 | Cost-Effectiveness of Proton Pump Inhibitor Co-Therapy in Patients Taking Aspirin for Secondary Prevention of Ischemic Stroke. ( Kawakami, K; Murata, K; Takabayashi, N; Tanaka, S, 2015) |
| "The benefit of aspirin in primary prevention of myocardial infarction and the associated gastro-intestinal bleeding risks have not been well established in the elderly population with diabetes." | 7.80 | Myocardial infarction and gastro-intestinal bleeding risks associated with aspirin use among elderly individuals with type 2 diabetes. ( Grégoire, JP; Moisan, J; Poirier, P; Sirois, C, 2014) |
| "Little is known about how discontinuation of low-dose aspirin therapy after peptic ulcer bleeding affects patient mortality or acute cardiovascular events." | 7.79 | Discontinuation of low-dose aspirin therapy after peptic ulcer bleeding increases risk of death and acute cardiovascular events. ( Bottai, M; Derogar, M; Lu, Y; Lundell, L; Orsini, N; Sadr-Azodi, O; Sandblom, G, 2013) |
| "Regular use of aspirin or NSAIDs is associated with an increased risk of diverticulitis and diverticular bleeding." | 7.77 | Use of aspirin or nonsteroidal anti-inflammatory drugs increases risk for diverticulitis and diverticular bleeding. ( Chan, AT; Giovannucci, EL; Huang, ES; Liu, YL; Strate, LL, 2011) |
| "We classified 1,041 gastroduodenal ulcer patients into three groups [patients taking LDA (group A), patients taking nonaspirin nonsteroidal anti-inflammatory drug (NSAID) (group N), and patients taking neither aspirin nor nonaspirin NSAID (group C)] and 241 bleeding gastroduodenal ulcer patients into three corresponding groups (groups a, n, and c)." | 7.76 | Clinical features of gastroduodenal ulcer in Japanese patients taking low-dose aspirin. ( Hirayama, T; Honda, A; Ikegami, T; Ito, M; Iwamoto, J; Matsuzaki, Y; Mizokami, Y; Saito, Y; Shimokobe, K, 2010) |
| "Data regarding the influence of dose and duration of aspirin use on risk of gastrointestinal bleeding are conflicting." | 7.76 | A prospective study of aspirin use and the risk of gastrointestinal bleeding in men. ( Chan, AT; Ho, WW; Huang, ES; Lee, SS; Strate, LL, 2010) |
| "To investigate the usefulness of anti-ulcer drugs for the prevention and treatment of low-dose aspirin-induced peptic ulcer." | 7.75 | Usefulness of anti-ulcer drugs for the prevention and treatment of peptic ulcers induced by low doses of aspirin. ( Arai, S; Imai, Y; Inao, M; Ishikawa, K; Mochida, S; Nagoshi, S; Nakashima, S; Nakayama, N; Ota, S; Yoshino, K, 2009) |
| "This multicenter retrospective study investigated the management and outcome of patients with peptic ulcer/erosion-related aspirin and clopidogrel (A + C) cotherapy." | 7.74 | Management and outcome of peptic ulcers or erosions in patients receiving a combination of aspirin plus clopidogrel. ( Chan, P; Cheung, TK; Kng, C; Kwanching, CP; Lai, ST; Loo, CK; Ng, FH; Ng, KM; Wong, BC; Wong, SY, 2008) |
| "To identify the risk factors for myocardial ischemia in patients undergoing aspirin therapy for coronary artery disease (CAD) presenting with upper gastrointestinal hemorrhage and to ascertain the impacts on mortality and length of hospital stay." | 7.74 | Silent myocardial ischemia in coronary artery disease patients under aspirin therapy presenting with upper gastrointestinal hemorrhage. ( Chen, CC; Chong, CF; Kuo, CD; Wang, TL, 2007) |
| "Silent myocardial ischemia (SMI) is a relatively common complication in patients with coronary artery disease (CAD) under aspirin therapy presenting with upper gastrointestinal hemorrhage (UGIH)." | 7.74 | A risk score to predict silent myocardial ischemia in patients with coronary artery disease under aspirin therapy presenting with upper gastrointestinal hemorrhage. ( Chen, CC; Chong, CF; Kuo, CD; Wang, TL, 2007) |
| "The combination of aspirin, clopidogrel, and enoxaparin (combination therapy) is the standard treatment for acute coronary syndrome but is associated with gastrointestinal bleeding." | 7.74 | Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel, and enoxaparin in acute coronary syndrome. ( Chang, CM; Chu, WM; Lam, KF; Lau, YK; Ng, FH; Wong, BC; Wong, SY, 2008) |
| "The proportional benefit gained from the use of low dose aspirin by the prevention of myocardial infarctions (-389 in men, -321 in women) and ischaemic stroke (-19 in men and -35 in women) is offset by excess gastrointestinal (499 in men, 572 in women) and intracranial (76 in men, 54 in women) bleeding." | 7.73 | Epidemiological modelling of routine use of low dose aspirin for the primary prevention of coronary heart disease and stroke in those aged > or =70. ( Bertram, M; Liew, D; Nelson, MR; Vos, T, 2005) |
| "Aspirin and statins are both effective for primary prevention of coronary heart disease (CHD), but their combined use has not been well studied." | 7.73 | Aspirin, statins, or both drugs for the primary prevention of coronary heart disease events in men: a cost-utility analysis. ( Earnshaw, S; Pignone, M; Pletcher, MJ; Tice, JA, 2006) |
| "A total of 991 patients with coronary artery disease (CAD) on low-dose aspirin were prospectively followed-up for two years for the occurrence and clinical features of first hospitalized episode of UGIB." | 7.73 | Incidence and predictors of upper gastrointestinal bleeding in patients receiving low-dose aspirin for secondary prevention of cardiovascular events in patients with coronary artery disease. ( Chen, WH; Cheng, X; Lai, KC; Lam, KF; Lau, CP; Lee, PY; Li, SW; Ng, M; Ng, W; Tse, HF; Wong, WM, 2006) |
| "During the period from January 2000 to May 2002, 70 patients who were prescribed clopidogrel (75 mg/day) for a previous history of non-aspirin-related peptic ulcer disease or a history of aspirin-related gastrointestinal complications (dyspepsia or peptic ulcer) were recruited." | 7.72 | High incidence of clopidogrel-associated gastrointestinal bleeding in patients with previous peptic ulcer disease. ( Chang, CM; Chen, WH; Kng, C; Lanas, AI; Ng, FH; Wong, BC; Wong, SY, 2003) |
| "The Framingham Heart Study records of participants with atrial fibrillation (AF) during 1980 and 1994 were retrospectively reviewed to determine the prevalence of warfarin and aspirin use in AF." | 7.72 | Warfarin and aspirin use and the predictors of major bleeding complications in atrial fibrillation (the Framingham Heart Study). ( Benjamin, EJ; D'Agostino, RB; Lambert, JW; Levy, D; Massaro, JM; Sam, C; Wolf, PA, 2004) |
| "To analyse the incidence and factors influencing the occurrence of UGIB in patients taking low-dose aspirin for the prevention of cardiovascular diseases outside clinical trials." | 7.71 | Risk of upper gastrointestinal bleeding in patients taking low-dose aspirin for the prevention of cardiovascular diseases. ( Arroyo, MT; Ferreira, IJ; Lanas, A; Serrano, P, 2002) |
| "To compare the outcome of 76 patients who presented with severe peptic ulcer haemorrhage whilst taking nonsteroidal anti-inflammatory drugs (NSAIDs) or aspirin with that of 112 patients who were not taking these drugs and who developed peptic ulcer haemorrhage over the same time period." | 7.69 | The outcome of peptic ulcer haemorrhage in relation to consumption of nonsteroidal anti-inflammatory drugs or aspirin. ( Choudari, CP; Elton, RA; Palmer, KR, 1994) |
| "Although gastrointestinal hemorrhage is a well-recognized complication of aspirin therapy, this side effect has not been previously reported in patients with Kawasaki disease (KD)." | 7.69 | Gastrointestinal hemorrhage complicating aspirin therapy in acute Kawasaki disease. ( Burns, JC; Kashani, IA; Kligerman, M; Mason, W; Matsubara, T, 1996) |
| "We conducted a retrospective case-control study to compare the frequency of myocardial infarction (MI) or unstable angina (UA) precipitated by aspirin-induced upper gastrointestinal (GI) bleeding among patients with and without ischemic heart disease(IHD), and to determine whether the risk of MI or UA is related to the hemoglobin level on admission." | 7.69 | Low dose aspirin in patients with ischemic heart disease may precipitate secondary myocardial infarction. ( Amital, H; Bar Dayan, Y; Levy, Y; Shoenfeld, Y, 1996) |
| "We present a series of fifteen patients treated with low dose aspirin for secondary prevention of ischemic heart disease who had upper GI bleeding and were admitted to our hospital because of unstable angina or myocardial infarction." | 7.69 | Aspirin for prevention of myocardial infarction. A double-edged sword. ( Amital, H; Bar-Dayan, Y; Levy, Y; Shoenfeld, Y, 1997) |
| "This study was performed to determine the relationship between net ion fluxes across the rat gastric mucosa and gastric mucosal damage after gastric ischemia and after intravenous administration of acetylsalicylic acid, and to determine the effect of cimetidine on these parameters." | 7.67 | Effect of cimetidine on net ion fluxes across the rat gastric mucosa during mucosal damage after gastric ischemia and after intravenous acetylsalicylic acid. ( Parsons, ME; Pipkin, G; Price, CA, 1984) |
| "Incidences of cardiovascular diseases, cancers, gastrointestinal bleeding, ulcers, and cataracts were compared in participants who did and did not take aspirin daily." | 7.67 | Aspirin use and chronic diseases: a cohort study of the elderly. ( Chao, A; Henderson, BE; Paganini-Hill, A; Ross, RK, 1989) |
| "Fifty-six patients who presented with non-steroidal anti-inflammatory drug-associated duodenal ulcers received maintenance treatment with ranitidine." | 7.67 | Ranitidine maintenance treatment of non-steroidal anti-inflammatory drug-induced duodenal ulceration. ( Penston, JG; Wormsley, KG, 1989) |
| "Aspirin-induced gastritis and gastrointestinal hemorrhage were reviewed and discussed on the basis of currently available literature." | 7.65 | Aspirin-induced gastritis and gastrointestinal bleeding. ( Gartner, AH, 1976) |
| "The effect of aspirin (acetylsalicylic acid) ingestion on occult gastrointestinal blood loss has been studied in patients with treated Addisonian pernicious anaemia and proved achlorhydria and in control patients able to secrete hydrochloric acid." | 7.65 | Influence of achlorhydria on aspirin-induced occult gastrointestinal blood loss: studies in Addisonian pernicious anaemia. ( John, DJ; McDermott, FT, 1970) |
| "The misoprostol/aspirin-treated group had significantly (P < 0." | 6.67 | Use of synthetic prostaglandin E1 (misoprostol) for prevention of aspirin-induced gastroduodenal ulceration in arthritic dogs. ( Boudrieau, RJ; Labato, MA; Matz, ME; Murtaugh, RJ, 1993) |
| " Although administration of antiplatelet agents has been confirmed to be one of the major approaches for secondary prevention of noncardioembolic stroke, the short-term or long-term use of aspirin plus clopidogrel for secondary stroke prevention remains to be controversial." | 6.52 | Dual antiplatelet therapy with clopidogrel and aspirin for secondary stroke prevention. ( Chen, W; Wang, Y, 2015) |
| "Thirty-six randomized control trials of aspirin compared with another dosage of aspirin or with placebo." | 6.39 | Efficacy and safety of different aspirin dosages on vascular diseases in high-risk patients. A metaregression analysis. ( Cappelleri, JC; Chalmers, TC; Kupelnick, B; Lau, J, 1995) |
| "Combining aspirin or nonsteroidal anti-inflammatory drugs with SSRIs for the treatment of interferon-associated neuropsychiatric side effects increases the risks of hemorrhage in patients with HCV who have developed cirrhosis and either portal hypertension or hepatic failure or both." | 6.20 | A critical review of selective serotonin reuptake inhibitor-associated bleeding: balancing the risk of treating hepatitis C-infected patients. ( Auriacombe, M; Chang, KM; Lewis, JD; Lynch, KG; Weinrieb, RM, 2003) |
| "In this post hoc secondary analysis of the ADAPTABLE randomized clinical trial, enteric-coated aspirin was not associated with significantly higher risk of myocardial infarction, stroke, or death or with lower bleeding risk compared with uncoated aspirin, regardless of dose, although a reduction in bleeding with enteric-coated aspirin cannot be excluded." | 5.69 | Effectiveness and Safety of Enteric-Coated vs Uncoated Aspirin in Patients With Cardiovascular Disease: A Secondary Analysis of the ADAPTABLE Randomized Clinical Trial. ( Benziger, CP; Effron, MB; Farrehi, PM; Girotra, S; Gupta, K; Harrington, RA; Hernandez, AF; Jain, SK; Jones, WS; Knowlton, KU; Marquis-Gravel, G; Muñoz, D; Pepine, CJ; Polonsky, TS; Re, RN; Roe, MT; Rothman, RL; Sleem, A; Stebbins, A; Whittle, J; Wruck, LM, 2023) |
| "Patients (n = 505) undergoing percutaneous coronary intervention in whom capsule endoscopy demonstrated no ulcerations or bleeding (although erosions were permitted) after 6 months of dual antiplatelet therapy (DAPT) were randomly assigned to aspirin plus placebo (n = 168), clopidogrel plus placebo (n = 169), or aspirin plus clopidogrel (n = 168) for an additional 6 months." | 5.51 | Magnetically Controlled Capsule Endoscopy for Assessment of Antiplatelet Therapy-Induced Gastrointestinal Injury. ( Bao, D; Cui, M; Deng, J; Feng, J; Gao, W; Han, Y; Huang, Y; Jia, S; Jiang, C; Li, J; Li, Y; Li, Z; Liao, Z; Ma, S; Ma, Y; Qiu, M; Qu, P; Ru, L; Sheng, J; Stone, GW; Tao, L; Wang, B; Wang, J; Wang, X; Yang, K; Yang, S; Yang, Y; Zhang, W; Zhao, X, 2022) |
| "Retroperitoneal hematoma is a rare complication of psoas catheter placement, typically occurring several days after placement and in the setting of anticoagulation." | 5.43 | Acute Retroperitoneal Hematoma After Psoas Catheter Placement in a Patient with Myeloproliferative Thrombocytosis and Aspirin Therapy. ( Duncan, CM; Kopp, SL; Warner, NS, 2016) |
| "Recent studies have shown that aspirin consumption may reduce the risk of hepatocellular carcinoma (HCC), but their correlation is still not fully understood." | 5.41 | The relationship between aspirin consumption and hepatocellular carcinoma: a systematic review and meta-analysis. ( Chen, R; Lin, Z; Wang, S; Xu, Y; Yang, Z; Zuo, L, 2023) |
| "The aspirin was stopped immediately." | 5.39 | Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis). ( Alghamdi, M; Alhussaini, H; Almalki, AS; Alokaily, FA, 2013) |
| " Patients with newly diagnosed ischemic stroke who are just about to start Aspirin were assessed for eligibility and inclusion in our trial." | 5.34 | An investigation into the impact of enteric coated of aspirin in patients with newly diagnosed ischemic stroke (ECASIS). ( Abdallah, IM; Ahmed, MS; Ali, M; AlSaud, AE; Danjuma, MI; Elshafei, MN; Imam, Y; Mohamed, MFH; Obeidat, K; Parray, AS; Saeid, R, 2020) |
| "Results show the short-term risk of hemorrhage in treating patients with acute transient ischemic attack (TIA) or minor acute ischemic stroke (AIS) with clopidogrel plus aspirin or aspirin alone." | 5.30 | Risk for Major Hemorrhages in Patients Receiving Clopidogrel and Aspirin Compared With Aspirin Alone After Transient Ischemic Attack or Minor Ischemic Stroke: A Secondary Analysis of the POINT Randomized Clinical Trial. ( Barsan, W; Easton, JD; Elm, JJ; Farrant, M; Johnston, SC; Kim, AS; Lindblad, AS; Palesch, YY; Tillman, H, 2019) |
| "When myocardial infarction is due to coronary embolism from endocarditic valves standard thrombolysis regimes should be avoided." | 5.29 | Acute coronary embolism complicating aortic valve endocarditis treated with streptokinase and aspirin. A case report. ( Connolly, DL; Crowley, JJ; Dardas, PS; Kenny, A; Petch, MC, 1994) |
| "Aspirin was given orally in a single daily dose of 200 mg/kg for two days." | 5.28 | Acute effects of fever, fasting and aspirin on infant rat gastric mucosa. ( Chang, MH; Chen, PH; Chuang, YH; Liu, YC, 1989) |
| "Compare efficacy and safety of vonoprazan and lansoprazole for secondary prevention of low-dose aspirin (LDA)-associated peptic ulcers in a 24-week study and long-term extension therapy in separate study." | 5.27 | Vonoprazan prevents low-dose aspirin-associated ulcer recurrence: randomised phase 3 study. ( Ashida, K; Funao, N; Kawai, T; Matsumoto, Y; Mizokami, Y; Nishimura, A; Oda, K; Sugano, K, 2018) |
| "To elucidate the efficacy and safety between aspirin and clopidogrel, a multicenter randomized controlled trial was designed in AF patients with low stroke risk." | 5.24 | Rationale and Design for a Randomized Comparison of Efficacy and Safety between Aspirin and Clopidogrel in Atrial Fibrillation Patients with Low Stroke Risk: CESAC-AF trial. ( Bang, CS; Hong, KS; Hong, MK; Jeong, H; Jung, MH; Kim, CY; Park, SM, 2017) |
| "To assess the impact of prophylactic omeprazole with background dual anti-platelet therapy on patient-reported symptoms of dyspepsia compared to placebo." | 5.20 | The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial. ( Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; McIntosh, AI; Schnitzer, TJ; Vardi, M, 2015) |
| " Patients with Helicobacter pylori infection and a history of peptic ulcer were assigned dual antiplatelet combination with omeprazole." | 5.17 | Effect of clopidogrel with or without omeprazole in patients with carotid artery stenting. ( Chen, G; Du, Y; Hang, L; Ma, B, 2013) |
| "Little is known about the efficacy of proton pump inhibitors compared with H(2) receptor antagonists in preventing adverse upper gastrointestinal complications in patients with acute coronary syndrome (ACS) or ST elevation myocardial infarction (STEMI) receiving aspirin, clopidogrel, and enoxaparin or thrombolytics." | 5.16 | Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction. ( Chan, K; Chu, WM; Keung, KK; Kng, C; Kwan, A; Lam, KF; Lau, YK; Li, A; Ng, FH; Tunggal, P; Wong, BC, 2012) |
| "Adding clopidogrel to aspirin beyond 4 weeks post PCI is not associated with a significant increase in the overall rate of major or minor bleeding, although it is associated with an increase in major gastrointestinal bleeding in the year after a PCI." | 5.14 | Bleeding risk associated with 1 year of dual antiplatelet therapy after percutaneous coronary intervention: Insights from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial. ( Aronow, HD; Berger, PB; Brennan, DM; Steinhubl, SR; Topol, EJ, 2009) |
| "Little is known about the efficacy of H(2)-receptor antagonists in preventing recurrence of aspirin-related peptic ulcers." | 5.14 | Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions. ( Chan, P; Chu, WM; Kng, C; Kwan, A; Lam, KF; Lau, YK; Ling, YH; Ng, FH; Wong, BC; Wong, SY; Yuen, WC, 2010) |
| "It is uncertain whether aspirin therapy should be continued after endoscopic hemostatic therapy in patients who develop peptic ulcer bleeding while receiving low-dose aspirin." | 5.14 | Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trial. ( Chan, FK; Ching, JY; Chiu, PW; Lau, JY; Lee, YT; Leung, VK; Sung, JJ; Wong, VW; Wu, JC, 2010) |
| "Taking aspirin does not increase the risk of hematuria and hematospermia after TRUS-PB." | 5.12 | Safety of transrectal ultrasound-guided prostate biopsy in patients receiving aspirin: An update meta-analysis including 3373 patients. ( Chen, C; Chen, D; Liu, G; Liu, Y; Luo, Z; Xie, Y, 2021) |
| " Combined warfarin and aspirin therapy was associated with greater fecal hemoglobin excretion than standard warfarin therapy, suggesting the potential for increased gastrointestinal hemorrhage." | 5.08 | Fecal hemoglobin excretion in elderly patients with atrial fibrillation: combined aspirin and low-dose warfarin vs conventional warfarin therapy. ( Ahlquist, DA; Baker, VS; Blackshear, JL; Ellefson, R; Hart, RG; Holland, A; Koehler, J; Litin, SC, 1996) |
| "Laboratory, clinical, and epidemiologic studies have recently suggested that regular use of aspirin can reduce colorectal cancer incidence or mortality." | 5.07 | Low-dose aspirin and incidence of colorectal tumors in a randomized trial. ( Buring, JE; Gann, PH; Glynn, RJ; Hennekens, CH; Manson, JE, 1993) |
| "We carried out a pilot study in 15 hemodialysis patients with recurrent vascular access thrombosis to examine whether the combination of low dose aspirin (85 mg once daily) and sulfinpyrazone (200 mg three times daily) is safe and effective in the prevention of vascular access thrombosis." | 5.07 | Combined aspirin and sulfinpyrazone in the prevention of recurrent hemodialysis vascular access thrombosis. ( Bauman, JE; Domoto, DT; Joist, JH, 1991) |
| "Per 1200 persons taking aspirin for primary prevention for 5 years, there will be 4 fewer MACEs, 3 fewer ischaemic strokes, 3 more intracranial haemorrhages and 8 more major bleeding events." | 5.05 | A comparison of contemporary versus older studies of aspirin for primary prevention. ( Ebell, MH; Moriarty, F, 2020) |
| " The most reported triplet were apixaban-aspirin-gastrointestinal hemorrhage." | 5.05 | Drug interactions with apixaban: A systematic review of the literature and an analysis of VigiBase, the World Health Organization database of spontaneous safety reports. ( Fernandez, S; Lenoir, C; Rollason, V; Samer, C, 2020) |
| "E 1 (misoprostol) as of SAMe, in the present of acute bleeding gastritis induced by 1300 mg aspirin in a single dose and during 2 hours." | 5.05 | [Prostaglandin E1 (misoprostol) and S-adenosylmethionine in the prevention of hemorrhagic gastritis induced by aspirin in the human. Endoscopic, histologic and histochemical study]. ( Capdepon, E; Finkelstein, D; Laudanno, OM, 1984) |
| " Gastrointestinal side effects with benoxaprofen compared favorably to those reported during aspirin and ibuprofen therapy, with peptic ulcers reported in 0." | 5.05 | Long-term safety of benoxaprofen. ( Mikulaschek, WM, 1980) |
| " Fourteen patients with rheumatoid arthritis received equivalent therapeutic doses of the antinflammatory drugs aspirin, 4 gm/day, and fenoprofen calcium, 2." | 5.04 | Gastrointestinal blood loss. Effect of aspirin, fenoprofen, and acetaminophen in rheumatoid arthritis as determined by sequential gastroscopy and radioactive fecal markers. ( Craig, RM; Culic, DD; Falk, J; Loebl, DH; Ridolfo, AS; Schmid, FR, 1977) |
| "To determine the effectiveness of naproxen in the treatment of osteoarthritis of the knee joint, a double-blind cross-over study against placebo was carried out on 61 patients." | 5.04 | Double-blind study of Naproxen in osteoarthritis of the knee joint. ( Ito, T; Mori, E; Muroga, T; Nakajima, A; Tanaka, S, 1976) |
| "In a double-blind between-patient study of aspirin and benorylate carried out in 72 outpatients with rheumatoid arthritis, benorylate 4 g twice daily was shown to be an effective analgesic and anti-inflammatory drug, its effects being indistinguishable from those of aspirin 1." | 5.03 | Comparison of aspirin and benorylate in the treatment of rheumatoid arthritis. ( Beales, DL; Burry, HC; Grahame, R, 1972) |
| "Aspirin reduces the risk of nonfatal myocardial infarction and stroke, and the risk of colorectal cancer." | 4.95 | Aspirin for Primary Prevention. ( Owens, DK; Richman, IB, 2017) |
| "Aspirin has been the mainstay for secondary prevention of coronary artery disease to decrease early recurrence and severity of recurrent cardiovascular events." | 4.95 | Usefulness of PA32540 in Protecting the Gastric Layer While Providing Secondary Prevention for Coronary Artery Disease. ( Haseeb, S; Kagolanu, D; Lam, P; Munnangi, S; Sayedy, N; Shah, S; Stephenson, K; Viswanathan, P, 2017) |
| "Aspirin is indicated for primary and secondary prevention of cardiovascular diseases (CVD) by major guidelines." | 4.95 | Efficacy of aspirin (325 mg) + omeprazole (40 mg) in treating coronary artery disease. ( Bliden, K; Chaudhary, R; Gurbel, PA; Sharma, T; Tantry, U, 2017) |
| " PPIs are the mainstay therapeutic agents for prophylaxis against aspirin gastropathy and for acid-related disorders including gastroesophageal reflux disease." | 4.95 | East Asian perspective on the interaction between proton pump inhibitors and clopidogrel. ( Goh, KL; Zou, D, 2017) |
| "To evaluate the risk for serious bleeding with regular aspirin use in cardiovascular disease (CVD) primary prevention." | 4.93 | Bleeding Risks With Aspirin Use for Primary Prevention in Adults: A Systematic Review for the U.S. Preventive Services Task Force. ( Burda, BU; Evans, CV; Guirguis-Blake, JM; Whitlock, EP; Williams, SB, 2016) |
| "Aspirin and gastric ulcer interaction are used as an example to illustrate this concept, especially the narration of how disease affects drug efficacy." | 4.93 | Drug-disease interactions: narrative review of aspirin in gastric ulcer. ( Nwose, EU; Yee, KC, 2016) |
| "To review advances in the individualized assessment for ASCVD and bleeding risk, and to provide an update of the randomized clinical trial evidence that examined the use of aspirin for primary prevention (primarily for ASCVD, and secondarily for colorectal cancer)." | 4.93 | Aspirin for Primary Prevention of Atherosclerotic Cardiovascular Disease: Advances in Diagnosis and Treatment. ( Manson, JE; Mora, S, 2016) |
| "The use of low-dose aspirin (LDA) is well known to be associated with an increased risk of serious upper gastrointestinal complications, such as peptic ulceration and bleeding." | 4.91 | Small bowel injury in low-dose aspirin users. ( Endo, H; Higurashi, T; Kato, T; Nakajima, A; Ohkubo, H; Sakai, E; Umezawa, S, 2015) |
| "This review highlights practical aspects related to aspirin therapy in cardiovascular diseases, specifically, the benefits and hazards in different clinical settings." | 4.91 | A Balanced View of Efficacy and Safety of Aspirin in Cardiovascular Diseases. ( Brugada, P; Casado-Arroyo, R; Lanas, A, 2015) |
| "Aspirin is widely used for secondary prevention after stroke." | 4.87 | Cilostazol versus aspirin for secondary prevention of vascular events after stroke of arterial origin. ( Husain, MR; Kamal, AK; Khealani, BA; Naqvi, I, 2011) |
| "Aspirin prevents deaths, myocardial infarction, and ischemic stroke, and increases hemorrhagic stroke and major bleeding when used in the primary prevention of cardiovascular disease." | 4.87 | Effect of aspirin on mortality in the primary prevention of cardiovascular disease. ( Eikelboom, J; Hirsh, J; O'Donnell, M; Raju, N; Sobieraj-Teague, M, 2011) |
| "Standard double antiplatelet therapy (aspirin plus clopidogrel) used in patients with coronary artery disease during acute coronary syndromes (ACS) and/or in conjunction with percutaneous coronary interventions (PCI) has some limitations." | 4.86 | [Antiplatelet therapy in coronary heart disease. Some problems and achivements]. ( Gratsianskiĭ, NA, 2010) |
| "We compared the efficacy and safety of cilostazol and aspirin in 2,672 Japanese patients with non-cardioembolic ischemic stroke." | 4.86 | [Results of the Cilostazol Stroke Prevention Study II (CSPS II): a randomized controlled trial for the comparison of cilostazol and aspirin in stroke patients]. ( Uchiyama, S, 2010) |
| "To determine the benefits and harms of taking aspirin for the primary prevention of myocardial infarctions, strokes, and death." | 4.85 | Aspirin for the primary prevention of cardiovascular events: an update of the evidence for the U.S. Preventive Services Task Force. ( Ko, S; Miller, T; Wolff, T, 2009) |
| "Aspirin is the best chemoprevention agent for colorectal cancer risk reduction despite the fact that the evidence for a decrease in mortality is weak." | 4.84 | Cyclooxygenase-2 inhibitors in colorectal cancer prevention: counterpoint. ( Hunt, R; Jankowski, J, 2008) |
| "A prespecified pooled intent-to-treat analysis of three double-blind randomised comparisons of etoricoxib (60 or 90 mg daily) and diclofenac (150 mg daily) in 34 701 patients with osteoarthritis or rheumatoid arthritis was done for upper gastrointestinal clinical events (bleeding, perforation, obstruction, or ulcer) and the subset of complicated events (perforation, obstruction, witnessed ulcer bleeding, or significant bleeding)." | 4.84 | Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. ( Cannon, CP; Cryer, B; Curtis, SP; Kaur, A; Laine, L, 2007) |
| "Aspirin is the main actor in primary and secondary preventive treatments in cardiovascular diseases." | 4.84 | Aspirin and gastrointestinal toxicity. ( Törüner, M, 2007) |
| "This review examines ulcers and gastrointestinal bleeding with low-dose aspirin, focusing on randomized placebo-controlled trials." | 4.83 | Review article: gastrointestinal bleeding with low-dose aspirin - what's the risk? ( Laine, L, 2006) |
| "Based on current references four clinical scenarios were discussed and different management strategies were compared for secondary and primary prophylaxis of ulcer or peptic ulcer bleeding under continuous therapy with non-steroidal antiinflammatory drugs (NSAID) or low-dose-aspirin, for H." | 4.82 | [Secondary and primary prophylaxis of gastropathy associated with nonsteroidal antiinflammatory drugs or low-dose-aspirin: a review based on four clinical scenarios]. ( Ittel, TH; Limmer, S; Wietholtz, H, 2003) |
| "According to meta-analysis and the results of the two studies with the highest power, aspirin is effective in primary prevention of coronary heart disease." | 4.82 | [Primary prevention of coronary heart disease with aspirin]. ( Darius, H; Kübler, W, 2005) |
| "1) Randomized trials at least 1 year in duration that examined aspirin chemoprevention in patients without previously known cardiovascular disease and 2) systematic reviews, recent trials, and observational studies that examined rates of hemorrhagic strokes and gastrointestinal bleeding secondary to aspirin use." | 4.81 | Aspirin for the primary prevention of cardiovascular events: a summary of the evidence for the U.S. Preventive Services Task Force. ( Hayden, M; Mulrow, C; Phillips, C; Pignone, M, 2002) |
| "Replacement of thienopyridine with aspirin or cilostazol may be acceptable for minimizing both the risk of post-ESD bleeding and thromboembolism in patients with EGC." | 4.31 | Association between perioperative management of antiplatelet agents and risk of post-endoscopic submucosal dissection bleeding in early gastric cancer: analysis of a nationwide multicenter study. ( Asahina, Y; Fujishiro, M; Hasatani, K; Hatta, W; Hayashi, Y; Hikichi, T; Hoteya, S; Iguchi, M; Inoue, T; Kikuchi, D; Kiyotoki, S; Kobayashi, M; Kuribayashi, S; Mabe, K; Masamune, A; Matsumura, T; Michida, T; Mikami, T; Miura, Y; Morita, Y; Nagami, Y; Nakamatsu, D; Narasaka, T; Nebiki, H; Nishikawa, J; Ohnita, K; Sugimoto, M; Sumiyoshi, T; Suzuki, H; Tomida, H; Tsuji, S; Tsuji, Y; Ueyama, H; Yabuuchi, Y; Yada, T; Yamaguchi, S; Yoshio, T, 2023) |
| "Long-term use of aspirin and severity of cerebral infarction are risk factors for gastrointestinal bleeding in cerebral infarction patients receiving dual antiplatelet therapy." | 4.31 | Risk factors for gastrointestinal bleeding in patients with cerebral infarction after dual antiplatelet therapy. ( Huang, J; Liao, F; Shu, X; Tang, J, 2023) |
| " Patients with diagnosis codes for ischemic stroke without cardiac disease were included and divided into two groups, those receiving cilostazol and those receiving clopidogrel." | 4.31 | Long-term effectiveness and safety of cilostazol versus clopidogrel in secondary prevention of noncardioembolic ischemic stroke. ( Je, NK; Lee, YJ, 2023) |
| "This cohort study demonstrated that regular aspirin use was associated with a reduced risk of liver disease in men without an elevated risk of gastrointestinal bleeding or ulcers." | 4.31 | Aspirin is associated with a reduced incidence of liver disease in men. ( Alqahtani, S; Creasy, KT; Hehl, L; Krishnan, A; Rader, DJ; Rendel, MD; Schneider, CV; Schneider, KM; Scorletti, E; Seeling, KS; Serper, M; Trautwein, C; Vell, MS; Vujkovic, M; Wangensteen, K; Zandvakili, I, 2023) |
| " Methods Using a comprehensive computerized hospital database, severe and non-severe diverticular bleeding cases were compared for 19 factors: the age, sex, body mass index, comorbid conditions (hypertension, cardiovascular disease, cerebrovascular disease, and chronic renal failure, including those undergoing dialysis), history of diverticular bleeding, use of low-dose aspirin, use of antiplatelet agent besides aspirin, use of anticoagulant agent, use of prednisolone, use of non-steroidal anti-inflammatory drugs, use of cyclooxygenase-2 selective inhibitors, changes in vital signs, hypoalbuminemia, bilateral diverticula, identification of bleeding lesion, and rebleeding." | 4.12 | Construction of a Model for Predicting the Severity of Diverticular Bleeding in an Elderly Population. ( Isomoto, H; Mikamo, T; Nakashima, A; Okada, T; Tanaka, K; Yanagitani, A, 2022) |
| "This retrospective multicenter study provides first data indicating a beneficial effect of aspirin on transplant-free survival after TIPS implantation in patients with refractory ascites." | 4.12 | Aspirin improves transplant-free survival after TIPS implantation in patients with refractory ascites: a retrospective multicentre cohort study. ( Bettinger, D; Gu, W; Heinzow, H; Huber, JP; Jansen, C; Köhler, M; Maschmeier, M; Masthoff, M; Meyer, C; Praktiknjo, M; Schindler, P; Schmidt, HH; Schoster, M; Schultheiss, M; Seifert, LL; Seifert, QE; Sturm, L; Trebicka, J; Weller, JF; Wildgruber, M; Wilms, C, 2022) |
| "The US Preventive Services Task Force (USPSTF) is updating its 2016 recommendation on the use of aspirin for the primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC)." | 4.12 | Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force. ( Dehmer, SP; Evans, CV; Guirguis-Blake, JM; Maciosek, MV; O'Keefe, LR; Perdue, LA, 2022) |
| "In the prevalent-user design, there was no significant association between low-dose aspirin and gastric ulcer observed in both cohorts." | 4.12 | Strongly increased risk of gastric and duodenal ulcers among new users of low-dose aspirin: results from two large cohorts with new-user design. ( Brenner, H; Chen, LJ; Holleczek, B; Nguyen, TNM; Schöttker, B; Sha, S, 2022) |
| " Patients aged 80 years or older who received monotherapy with clopidogrel or aspirin following hospitalization for primary acute ischemic stroke between January 1, 2009, and December 31, 2018, were included." | 4.12 | Effectiveness and Safety of Clopidogrel vs Aspirin in Elderly Patients With Ischemic Stroke. ( Huang, HY; Katz, AJ; Lin, FJ; Lin, SY; Sheu, JJ; Wang, CC; Wu, CH, 2022) |
| "Uncertainty remains regarding the impact of enteric-coated aspirin (EC-ASA) on secondary prevention of ischemic stroke compared to plain aspirin (P-ASA)." | 4.12 | The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS) study. ( Abdallah, IM; Abdelmoneim, MS; Akhtar, N; Ali, M; Alsaud, AE; Ayadathil, R; Chandra, P; Danjuma, MI; Elshafei, MN; Imam, Y; Mohamed, MFH; Mohammed, S; Obeidat, K; Parray, A; Saeid, R, 2022) |
| "To examine the association between CAC, bleeding, and ASCVD and explore the net estimated effect of aspirin at different CAC thresholds." | 4.02 | Value of Coronary Artery Calcium Scanning in Association With the Net Benefit of Aspirin in Primary Prevention of Atherosclerotic Cardiovascular Disease. ( Ajufo, E; Ayers, CR; de Lemos, JA; Joshi, PH; Khera, A; Rohatgi, A; Vigen, R, 2021) |
| "Aspirin may reduce the risk of chronic hepatitis B (CHB)-related hepatocellular carcinoma (HCC) in patients receiving antiviral treatment." | 4.02 | Aspirin Reduces the Incidence of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B Receiving Oral Nucleos(t)ide Analog. ( Chan, HL; Hui, VW; Lui, GC; Tse, YK; Wong, GL; Wong, VW; Yip, TC, 2021) |
| "More information is needed about the long-term effects of low-dose aspirin (≤160 mg) on incident hepatocellular carcinoma, liver-related mortality, and gastrointestinal bleeding in persons with chronic hepatitis B or hepatitis C virus infection." | 3.96 | Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality. ( Aleman, S; Chan, AT; Chung, RT; Duberg, AS; Ludvigsson, JF; Simon, TG, 2020) |
| " Here, we describe a 3-year-old boy with typical KD who had lower gastrointestinal bleeding caused by rectal ulcers on the third day of aspirin therapy." | 3.96 | A case of rectal ulcers during aspirin therapy in acute Kawasaki disease. ( Han, Y; Hu, C; Yu, Y, 2020) |
| "Aspirin may increase the risk of lower gastrointestinal bleeding (LGIB) from precursors of colorectal cancer (CRC)." | 3.96 | Risk of lower gastrointestinal bleeding and colorectal neoplasms following initiation of low-dose aspirin: a Danish population-based cohort study. ( Erichsen, R; Farkas, DK; Sørensen, HT; Troelsen, FS, 2020) |
| "Comparative gastrointestinal bleeding (GIB) risk between rivaroxaban and low-dose aspirin is unknown in patients with atrial fibrillation (AF)." | 3.96 | Gastrointestinal bleeding risk with rivaroxaban vs aspirin in atrial fibrillation: A multinational study. ( Bell, JS; Chan, EW; Darzins, P; Fanning, L; Ilomaki, J; Lau, WCY; Leung, WK; Li, X; Man, KKC; Mongkhon, P; Wei, L; Wong, ICK, 2020) |
| "Several clinical trials reported that clopidogrel was superior to aspirin in secondary stroke prevention by reducing the risk of major adverse cardiovascular events (MACE)." | 3.91 | Aspirin better than clopidogrel on major adverse cardiovascular events reduction after ischemic stroke: A retrospective nationwide cohort study. ( Chan, L; Chen, YC; Hsu, CY; Hu, CJ; Lin, CL; Muo, CH; Vidyanti, AN; Wu, D, 2019) |
| "To investigate the correlation of tumor necrosis factor α (TNF-α) polymorphisms with upper gastrointestinal bleeding (UGIB) induced by enteric-coated aspirin in coronary heart disease (CHD) patients." | 3.91 | Association between TNF-α polymorphisms and the risk of upper gastrointestinal bleeding induced by aspirin in patients with coronary heart disease. ( Wang, TP, 2019) |
| "Aspirin, commonly used for prevention of cardiovascular and cerebrovascular diseases, is well known to protect against development of colorectal cancer (CRC) but increases risk of gastrointestinal bleeding (GIB)." | 3.88 | Risk of gastrointestinal bleeding and benefit from colorectal cancer reduction from long-term use of low-dose aspirin: A retrospective study of 612 509 patients. ( Chan, FC; Hirai, HW; Sung, JJ; Tsoi, KK, 2018) |
| " Cox proportional hazard regression models were developed to evaluate the predictors of LGIB with adjustments for age, gender, comorbidities including coronary artery disease, ischaemic stroke, diabetes, hypertension, chronic kidney disease, liver cirrhosis, chronic obstructive pulmonary disease, dyslipidemia, uncomplicated peptic ulcer disease, history of peptic ulcer bleeding, and concomitant use of clopidogrel, ticlopidine, warfarin, nonsteroidal anti-inflammatory drugs (NSAIDs), cyclooxygenase-2 inhibitors, steroids, proton pump inhibitors (PPIs), histamine-2 receptor antagonists (H2RAs), nitrates, alendronate, selective serotonin reuptake inhibitors (SSRIs) and calcium channel blockers." | 3.85 | The risk of lower gastrointestinal bleeding in low-dose aspirin users. ( Chen, WC; Chuah, SK; Hsu, PI; Huang, YT; Lin, KH; Sun, WC; Tsai, TJ; Wu, DC, 2017) |
| " Upper gastrointestinal bleeding is a serious complication, but had low case fatality in trials of aspirin and is not generally thought to cause long-term disability." | 3.85 | Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events: a population-based cohort study. ( Geraghty, OC; Li, L; Mehta, Z; Rothwell, PM, 2017) |
| "The initial EROSION study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography-Based Management in Plaque Erosion) demonstrated that patients with acute coronary syndrome caused by plaque erosion might be stabilized with aspirin and ticagrelor without stenting for ≤1 month." | 3.85 | EROSION Study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography-Based Management in Plaque Erosion): A 1-Year Follow-Up Report. ( Bryniarski, K; Hou, J; Hu, S; Jang, IK; Jia, H; Lee, H; Li, L; Liu, H; Ma, L; Sugiyama, T; Wang, C; Xing, L; Xu, M; Yamamoto, E; Yu, B; Zhang, S; Zhu, Y, 2017) |
| "Nonvitamin K antagonist oral anticoagulants (NOACs) are now available for the prevention of stroke in patients with atrial fibrillation (AF) as an alternative to vitamin K antagonists (VKA) and aspirin." | 3.85 | Risk of major bleeding and stroke associated with the use of vitamin K antagonists, nonvitamin K antagonist oral anticoagulants and aspirin in patients with atrial fibrillation: a cohort study. ( Bos, J; Burden, AM; de Boer, A; de Vries, F; Gieling, EM; Kramers, C; van den Ham, HA; van Onzenoort, H, 2017) |
| "Evidence indicates that aspirin is effective for the primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC) but also increases the risk for gastrointestinal (GI) and cerebral hemorrhages." | 3.83 | Aspirin for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: A Decision Analysis for the U.S. Preventive Services Task Force. ( Dehmer, SP; Flottemesch, TJ; LaFrance, AB; Maciosek, MV; Whitlock, EP, 2016) |
| "96) as well as history of hematemesis, melena in the past 30 days, positive nasogastric aspirate, prior upper gastrointestinal bleeding or use of aspirin or non-steroidal anti-inflammatory." | 3.83 | Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics. ( Camus, M; Dulai, GS; Ghassemi, KA; Jensen, DM; Jutabha, R; Khungar, V; Kovacs, TO; Machicado, GA; Ohning, GV, 2016) |
| "To evaluate the efficacy and safety of aspirin usage for coronary heart disease (CHD) primary prevention in patients with dyslipidemia." | 3.83 | Effects of low-dose aspirin in subjects with dyslipidemia. ( Chen, J; Lou, G; Xia, Y, 2016) |
| "This study aims to compare rates of venous thromboembolism (VTE), gastro-intestinal (GI) bleeding and mortality events, with use of new oral anticoagulants (NOAC) or low-molecular-weight heparins (LMWHs) compared with aspirin in patients undergoing total joint replacement." | 3.83 | Safety and efficacy of new oral anticoagulants and low-molecular-weight heparins compared with aspirin in patients undergoing total knee and hip replacements. ( Boonen, AE; Dagnelie, PC; de Vries, F; Emans, PJ; Lalmohamed, A; Nielen, JT; van den Bemt, BJ; van Staa, TP; Veldhorst-Janssen, N, 2016) |
| "The main innovations of the latest meeting of the Gastroenterological Association (2016) concerning upper gastrointestinal bleeding from the clinician's perspective can be summarised as follows: a) The Glasgow-Blatchford scale has the best accuracy in predicting the need for surgical intervention and hospital mortality; b) Prognostic scales for non-variceal upper gastrointestinal bleeding are also useful for lower gastrointestinal bleeding; c) Preliminary data suggest that treatment with hemospray does not seem to be superior to current standard treatment in controlling active peptic ulcer bleeding; d) Either famotidine or a proton pump inhibitor may be effective in preventing haemorrhagic recurrence in patients taking aspirin, but this finding needs to be confirmed in further studies; e) There was confirmation of the need to re-introduce antiplatelet therapy as early as possible in patients with antiplatelet-associated gastrointestinal bleeding in order to prevent cardiovascular mortality; f) Routine clinical practice suggests that gastrointestinal or cardiovascular complications with celecoxib or traditional NSAIDs are very low; g) Dabigatran is associated with an increased incidence of gastrointestinal bleeding compared with apixaban or warfarin." | 3.83 | Advances in gastrointestinal bleeding. ( Lanas, Á, 2016) |
| "Low-dose aspirin (ASA) is effective for secondary prevention of ischemic stroke but can increase the risks of hemorrhagic stroke, upper gastrointestinal bleeding (UGIB), and dyspepsia." | 3.81 | Cost-Effectiveness of Proton Pump Inhibitor Co-Therapy in Patients Taking Aspirin for Secondary Prevention of Ischemic Stroke. ( Kawakami, K; Murata, K; Takabayashi, N; Tanaka, S, 2015) |
| "Patients receiving alendronate for osteoporosis carry a significantly higher risk of developing upper gastrointestinal bleeding (GIB) and lower GIB (hazard ratio 1." | 3.80 | Alendronate, a bisphosphonate, increased upper and lower gastrointestinal bleeding: risk factor analysis from a nationwide population-based study. ( Hou, MC; Hu, HY; Lee, FY; Lin, HC; Luo, JC; Peng, YL, 2014) |
| "The benefit of aspirin in primary prevention of myocardial infarction and the associated gastro-intestinal bleeding risks have not been well established in the elderly population with diabetes." | 3.80 | Myocardial infarction and gastro-intestinal bleeding risks associated with aspirin use among elderly individuals with type 2 diabetes. ( Grégoire, JP; Moisan, J; Poirier, P; Sirois, C, 2014) |
| "Increased incidence of coronary artery disease has led to the increased use of dual antiplatelet therapy composed of aspirin and clopidogrel." | 3.80 | [Clinical impact of dual antiplatelet therapy on peptic ulcer disease]. ( Ahn, DG; Kim, BJ; Kim, JG; Kim, JW, 2014) |
| "Chronic constipation, enteric-coated aspirin intake and splanchnic atherosclerosis are risk factors related to ulcer in IC patients." | 3.80 | [An analysis of clinical characteristics and risk factors for ulceration in ischemic colitis]. ( Li, X; Liao, L; Liu, W; Liu, Y; Shi, H; Wu, B, 2014) |
| "Recent evidence suggests that daily aspirin use decreases cancer risk, particularly for colorectal cancer, but evidence for alternate-day use is scant." | 3.79 | Alternate-day, low-dose aspirin and cancer risk: long-term observational follow-up of a randomized trial. ( Buring, JE; Cook, NR; Lee, IM; Moorthy, MV; Zhang, SM, 2013) |
| "Current guidelines offer a choice of P2Y12 receptor antagonist among clopidogrel, prasugrel or ticagrelor on top of aspirin (ASA) for dual antiplatelet therapy (DAPT) in patients after acute coronary syndromes (ACS)." | 3.79 | Gastrointestinal adverse events after dual antiplatelet therapy: clopidogrel is safer than ticagrelor, but prasugrel data are lacking or inconclusive. ( Can, MM; Dinicolantonio, JJ; Kuliczkowski, W; Pershukov, IV; Serebruany, VL, 2013) |
| "Little is known about how discontinuation of low-dose aspirin therapy after peptic ulcer bleeding affects patient mortality or acute cardiovascular events." | 3.79 | Discontinuation of low-dose aspirin therapy after peptic ulcer bleeding increases risk of death and acute cardiovascular events. ( Bottai, M; Derogar, M; Lu, Y; Lundell, L; Orsini, N; Sadr-Azodi, O; Sandblom, G, 2013) |
| " In the management of aspirin-related uncomplicated peptic ulcers in patients requiring antiplatelet therapies, continuing aspirin plus a powerful proton pump inhibitor is the choice of treatment." | 3.78 | New look at antiplatelet agent-related peptic ulcer: an update of prevention and treatment. ( Hsu, PI, 2012) |
| " He had chronic constipation and had taken aspirin for about 10 years because of a previous brain infarction." | 3.78 | Massive life-threatening lower gastrointestinal hemorrhage caused by an internal hemorrhoid in a patient receiving antiplatelet therapy: a case report. ( Chang, WY; Cho, YK; Kim, HU; Kim, M; Kim, S; Kim, SH; Song, BC; Song, HJ, 2012) |
| " She was on dabigatran for atrial fibrillation and aspirin, with intermittent intake of ibuprofen." | 3.78 | Direct thrombin inhibitors: a case indicating benefit from 'plasmapheresis' in toxicity: a call for establishing "guidelines" in overdose and to find an "antidote"! ( Cirra, VR; Kamboj, J; Kamboj, R; Kottalgi, M; Shah, N, 2012) |
| " Old age, bilateral diverticulosis, presence of atherosclerosis related diseases (hypertension, diabetes mellitus, ischemic heart disease, obesity), use of aspirin, NSAIDs and calcium channel blocker, increased the risk of bleeding." | 3.78 | [The risk factors for colonic diverticular bleeding]. ( Hwang, JH; Jeong, SH; Jo, HJ; Jung, HC; Kim, HY; Kim, JW; Kim, N; Lee, DH; Lee, SH; Park, H; Park, YS; Seo, PJ; Shin, CM; Song, IS; Suh, S, 2012) |
| "The frequencies of hemorrhagic spots, erosions and peptic ulcers in the symptomatic clopidogrel users were 25%, 39% and 39%, respectively." | 3.78 | Upper gastrointestinal lesions in patients receiving clopidogrel anti-platelet therapy. ( Chan, HH; Chang, SN; Hsiao, SH; Hsu, PI; Huang, HR; Lai, KH; Lin, CH; Lin, CK; Lin, KH; Liu, CP; Tsai, TJ; Tsay, FW; Wang, HM; Wang, KM; Yu, HC, 2012) |
| "We have previously shown that co-treatment of angiotensin type 1 receptor (AT1R) blocker (ARB) or angiotensin converting enzyme (ACE) inhibitor seem to reduce peptic ulcer among patients taking low dose aspirin." | 3.77 | Renin-angiotensin system associated with risk of upper GI mucosal injury induced by low dose aspirin: renin angiotensin system genes' polymorphism. ( Haruma, K; Kamada, T; Matsumoto, H; Murao, T; Nishi, R; Sakakibara, T; Shiotani, A; Tarumi, K; Yamanaka, Y, 2011) |
| "Regular use of aspirin or NSAIDs is associated with an increased risk of diverticulitis and diverticular bleeding." | 3.77 | Use of aspirin or nonsteroidal anti-inflammatory drugs increases risk for diverticulitis and diverticular bleeding. ( Chan, AT; Giovannucci, EL; Huang, ES; Liu, YL; Strate, LL, 2011) |
| "Aspirin reduces myocardial infarction but increases gastrointestinal tract (GI) bleeding." | 3.77 | Cost-utility of aspirin and proton pump inhibitors for primary prevention. ( Earnshaw, SR; Fendrick, AM; McDade, C; Pignone, M; Scheiman, J, 2011) |
| "Increased baseline platelet reactivity as well as diabetes mellitus and acute coronary syndrome are associated with low aspirin response in the aged patients." | 3.77 | [Aspirin response and related factors in aged patients]. ( Fan, Y; Feng, XR; Liu, F; Liu, ML; Liu, QZ; Tian, QP, 2011) |
| "We classified 1,041 gastroduodenal ulcer patients into three groups [patients taking LDA (group A), patients taking nonaspirin nonsteroidal anti-inflammatory drug (NSAID) (group N), and patients taking neither aspirin nor nonaspirin NSAID (group C)] and 241 bleeding gastroduodenal ulcer patients into three corresponding groups (groups a, n, and c)." | 3.76 | Clinical features of gastroduodenal ulcer in Japanese patients taking low-dose aspirin. ( Hirayama, T; Honda, A; Ikegami, T; Ito, M; Iwamoto, J; Matsuzaki, Y; Mizokami, Y; Saito, Y; Shimokobe, K, 2010) |
| "To assess the association of low-dose aspirin use with the performance of 2 quantitative iFOBTs in a large sample of patients undergoing colorectal cancer screening." | 3.76 | Low-dose aspirin use and performance of immunochemical fecal occult blood tests. ( Brenner, H; Haug, U; Tao, S, 2010) |
| "Data regarding the influence of dose and duration of aspirin use on risk of gastrointestinal bleeding are conflicting." | 3.76 | A prospective study of aspirin use and the risk of gastrointestinal bleeding in men. ( Chan, AT; Ho, WW; Huang, ES; Lee, SS; Strate, LL, 2010) |
| " We report IDH secondary to aspirin therapy that was associated with transient obstructive jaundice and acute cholecystitis in a 47-year-old woman." | 3.76 | Spontaneous intramural duodenal haematoma with transient biliary obstruction and acute cholecystitis. ( Basir, N; Chong, VH, 2010) |
| "To investigate the usefulness of anti-ulcer drugs for the prevention and treatment of low-dose aspirin-induced peptic ulcer." | 3.75 | Usefulness of anti-ulcer drugs for the prevention and treatment of peptic ulcers induced by low doses of aspirin. ( Arai, S; Imai, Y; Inao, M; Ishikawa, K; Mochida, S; Nagoshi, S; Nakashima, S; Nakayama, N; Ota, S; Yoshino, K, 2009) |
| "Encourage men age 45 to 79 years to use aspirin when the potential benefit of a reduction in myocardial infarctions outweighs the potential harm of an increase in gastrointestinal hemorrhage." | 3.75 | Aspirin for the prevention of cardiovascular disease: U.S. Preventive Services Task Force recommendation statement. ( , 2009) |
| "This study was conducted to compare the risk of recurrent hospitalization for major gastrointestinal (GI) complications (peptic ulcer, bleeding, and perforation) in patients at high GI risk who require ongoing antiplatelet therapy (aspirin [acetylsalicylic acid] or clopidogrel) with or without proton pump inhibitors (PPIs)." | 3.75 | A comparison of aspirin and clopidogrel with or without proton pump inhibitors for the secondary prevention of cardiovascular events in patients at high risk for gastrointestinal bleeding. ( Chang, PY; Chen, PF; Hsiao, FY; Huang, WF; Kuo, KN; Tsai, YW; Wen, YW, 2009) |
| "Patients with coronary heart disease (CHD) require long-term therapy with low-dose aspirin (ASA)." | 3.74 | Cost-effectiveness of proton pump inhibitor cotherapy in patients taking long-term, low-dose aspirin for secondary cardiovascular prevention. ( Fendrick, AM; Saini, SD; Scheiman, J; Schoenfeld, P, 2008) |
| "This multicenter retrospective study investigated the management and outcome of patients with peptic ulcer/erosion-related aspirin and clopidogrel (A + C) cotherapy." | 3.74 | Management and outcome of peptic ulcers or erosions in patients receiving a combination of aspirin plus clopidogrel. ( Chan, P; Cheung, TK; Kng, C; Kwanching, CP; Lai, ST; Loo, CK; Ng, FH; Ng, KM; Wong, BC; Wong, SY, 2008) |
| "To identify the risk factors for myocardial ischemia in patients undergoing aspirin therapy for coronary artery disease (CAD) presenting with upper gastrointestinal hemorrhage and to ascertain the impacts on mortality and length of hospital stay." | 3.74 | Silent myocardial ischemia in coronary artery disease patients under aspirin therapy presenting with upper gastrointestinal hemorrhage. ( Chen, CC; Chong, CF; Kuo, CD; Wang, TL, 2007) |
| "Silent myocardial ischemia (SMI) is a relatively common complication in patients with coronary artery disease (CAD) under aspirin therapy presenting with upper gastrointestinal hemorrhage (UGIH)." | 3.74 | A risk score to predict silent myocardial ischemia in patients with coronary artery disease under aspirin therapy presenting with upper gastrointestinal hemorrhage. ( Chen, CC; Chong, CF; Kuo, CD; Wang, TL, 2007) |
| "The combination of aspirin, clopidogrel, and enoxaparin (combination therapy) is the standard treatment for acute coronary syndrome but is associated with gastrointestinal bleeding." | 3.74 | Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel, and enoxaparin in acute coronary syndrome. ( Chang, CM; Chu, WM; Lam, KF; Lau, YK; Ng, FH; Wong, BC; Wong, SY, 2008) |
| "A literature search was conducted using EMBASE (1980-January 2008), PubMed (1966-January 2008), Google, and a manual search of the reference lists using the search terms gastrointestinal bleed, gastrointestinal hemorrhage, peptic ulcer hemorrhage, ASA, aspirin, Plavix, clopidogrel, and PPI." | 3.74 | Single antiplatelet therapy for patients with previous gastrointestinal bleeds. ( Ackman, ML; Gellatly, RM, 2008) |
| "Thrombosis is not equivalent to hemostasis, but is a distortion of the hemostatic process." | 3.74 | Aspirin revisited. ( Cooke, AR; Rodvein, R, 1975) |
| "The proportional benefit gained from the use of low dose aspirin by the prevention of myocardial infarctions (-389 in men, -321 in women) and ischaemic stroke (-19 in men and -35 in women) is offset by excess gastrointestinal (499 in men, 572 in women) and intracranial (76 in men, 54 in women) bleeding." | 3.73 | Epidemiological modelling of routine use of low dose aspirin for the primary prevention of coronary heart disease and stroke in those aged > or =70. ( Bertram, M; Liew, D; Nelson, MR; Vos, T, 2005) |
| "We present a case of severe lower gastrointestinal bleeding due to appendiceal ulcer associated with intake of enteric coated aspirin." | 3.73 | [Active lower gastrointestinal bleeding due to appendiceal ulcer]. ( de Sola-Earle, C; Fernández-Moreno, N; Montiel Quezel-Guerraz, N; Palma-Carazo, F; Rivera-Irigoín, R, 2005) |
| "Warfarin and aspirin are commonly used to prevent cardiovascular diseases." | 3.73 | [Characteristics of colon cancer diagnosed in patients taking aspirin or warfarin]. ( Kim, BC; Kim, S; Kim, TI; Kim, WH; Park, S; Shin, SJ, 2005) |
| "In 674 upper gastrointestinal bleeders, we found that the odds ratio for the presence of erosive oesophagitis in aspirin users was 2 (95% CI, 1-3; P = 0." | 3.73 | Upper gastrointestinal mucosal abnormalities and blood loss complicating low-dose aspirin and antithrombotic therapy. ( Angerson, WJ; Blatchford, O; Knill-Jones, RP; Taha, AS, 2006) |
| "Aspirin and statins are both effective for primary prevention of coronary heart disease (CHD), but their combined use has not been well studied." | 3.73 | Aspirin, statins, or both drugs for the primary prevention of coronary heart disease events in men: a cost-utility analysis. ( Earnshaw, S; Pignone, M; Pletcher, MJ; Tice, JA, 2006) |
| "A total of 991 patients with coronary artery disease (CAD) on low-dose aspirin were prospectively followed-up for two years for the occurrence and clinical features of first hospitalized episode of UGIB." | 3.73 | Incidence and predictors of upper gastrointestinal bleeding in patients receiving low-dose aspirin for secondary prevention of cardiovascular events in patients with coronary artery disease. ( Chen, WH; Cheng, X; Lai, KC; Lam, KF; Lau, CP; Lee, PY; Li, SW; Ng, M; Ng, W; Tse, HF; Wong, WM, 2006) |
| "During the period from January 2000 to May 2002, 70 patients who were prescribed clopidogrel (75 mg/day) for a previous history of non-aspirin-related peptic ulcer disease or a history of aspirin-related gastrointestinal complications (dyspepsia or peptic ulcer) were recruited." | 3.72 | High incidence of clopidogrel-associated gastrointestinal bleeding in patients with previous peptic ulcer disease. ( Chang, CM; Chen, WH; Kng, C; Lanas, AI; Ng, FH; Wong, BC; Wong, SY, 2003) |
| "The Framingham Heart Study records of participants with atrial fibrillation (AF) during 1980 and 1994 were retrospectively reviewed to determine the prevalence of warfarin and aspirin use in AF." | 3.72 | Warfarin and aspirin use and the predictors of major bleeding complications in atrial fibrillation (the Framingham Heart Study). ( Benjamin, EJ; D'Agostino, RB; Lambert, JW; Levy, D; Massaro, JM; Sam, C; Wolf, PA, 2004) |
| "To analyse the incidence and factors influencing the occurrence of UGIB in patients taking low-dose aspirin for the prevention of cardiovascular diseases outside clinical trials." | 3.71 | Risk of upper gastrointestinal bleeding in patients taking low-dose aspirin for the prevention of cardiovascular diseases. ( Arroyo, MT; Ferreira, IJ; Lanas, A; Serrano, P, 2002) |
| ", omeprazole, misoprostol, and high-dose famotidine) in the prevention of NSAID-induced gastroduodenal ulcers will also be effective in this setting." | 3.71 | Current approaches to reducing gastrointestinal toxicity of low-dose aspirin. ( Lanas, AI, 2001) |
| "For older patients with atrial fibrillation and no other contraindications to antithrombotic therapy, a Markov decision-analytic model was used to determine the preferred treatment strategy (no antithrombotic therapy, long-term aspirin use, or long-term warfarin sodium use) based on their risk of major upper GI tract hemorrhage." | 3.71 | Balancing the risks of stroke and upper gastrointestinal tract bleeding in older patients with atrial fibrillation. ( Laupacis, A; Man-Son-Hing, M, 2002) |
| "To compare the outcome of 76 patients who presented with severe peptic ulcer haemorrhage whilst taking nonsteroidal anti-inflammatory drugs (NSAIDs) or aspirin with that of 112 patients who were not taking these drugs and who developed peptic ulcer haemorrhage over the same time period." | 3.69 | The outcome of peptic ulcer haemorrhage in relation to consumption of nonsteroidal anti-inflammatory drugs or aspirin. ( Choudari, CP; Elton, RA; Palmer, KR, 1994) |
| "Although gastrointestinal hemorrhage is a well-recognized complication of aspirin therapy, this side effect has not been previously reported in patients with Kawasaki disease (KD)." | 3.69 | Gastrointestinal hemorrhage complicating aspirin therapy in acute Kawasaki disease. ( Burns, JC; Kashani, IA; Kligerman, M; Mason, W; Matsubara, T, 1996) |
| "We conducted a retrospective case-control study to compare the frequency of myocardial infarction (MI) or unstable angina (UA) precipitated by aspirin-induced upper gastrointestinal (GI) bleeding among patients with and without ischemic heart disease(IHD), and to determine whether the risk of MI or UA is related to the hemoglobin level on admission." | 3.69 | Low dose aspirin in patients with ischemic heart disease may precipitate secondary myocardial infarction. ( Amital, H; Bar Dayan, Y; Levy, Y; Shoenfeld, Y, 1996) |
| "The aim of this case-control study was to assess the risk of bleeding from esophageal varices associated with aspirin and non-steroidal anti-inflammatory drug consumption." | 3.69 | Non-steroidal anti-inflammatory drugs and variceal bleeding: a case-control study. ( Barrioz, T; Beauchant, M; de Lédinghen, V; Foucher, J; Ingrand, P; Mannant, PR; Perault, MC; Silvain, C; Vandel, B, 1996) |
| "We present a series of fifteen patients treated with low dose aspirin for secondary prevention of ischemic heart disease who had upper GI bleeding and were admitted to our hospital because of unstable angina or myocardial infarction." | 3.69 | Aspirin for prevention of myocardial infarction. A double-edged sword. ( Amital, H; Bar-Dayan, Y; Levy, Y; Shoenfeld, Y, 1997) |
| "Aspirin and nonsteroidal antiinflammatory drugs have been implicated in the pathogenesis of gastrointestinal hemorrhage." | 3.68 | Nonsteroidal antiinflammatory drugs and upper gastrointestinal hemorrhage in an urban hospital. ( Dabezies, MA; Fisher, RS; Klein, WA; Klepper, L; Krevsky, B; Ljubich, P; Niewiarowski, TJ; Rothstein, KD, 1993) |
| "Recurrent chest pain with new ST-segment elevation was observed in 26 of 652 patients (4%) with myocardial infarction in a clinical trial of alteplase (recombinant tissue-type plasminogen activator; 100 mg) and aspirin with or without heparin." | 3.68 | Retreatment with alteplase for early signs of reocclusion after thrombolysis. The European Cooperative Study Group. ( Arnout, J; Nÿssen, K; Simoons, ML; van den Brand, M; Verstraete, M, 1993) |
| "We describe 13 patients who developed erosive gastritis with overt gastrointestinal bleeding while receiving 75-250 mg nonbuffered aspirin per day for the secondary prevention of cardiac or cerebrovascular events." | 3.68 | Overt gastrointestinal bleeding in the course of chronic low-dose aspirin administration for secondary prevention of arterial occlusive disease. ( Bassan, H; Levy, N; Naschitz, JE; Odeh, M; Rosner, I; Stermer, E; Yeshurun, D, 1990) |
| "This study was performed to determine the relationship between net ion fluxes across the rat gastric mucosa and gastric mucosal damage after gastric ischemia and after intravenous administration of acetylsalicylic acid, and to determine the effect of cimetidine on these parameters." | 3.67 | Effect of cimetidine on net ion fluxes across the rat gastric mucosa during mucosal damage after gastric ischemia and after intravenous acetylsalicylic acid. ( Parsons, ME; Pipkin, G; Price, CA, 1984) |
| "Incidences of cardiovascular diseases, cancers, gastrointestinal bleeding, ulcers, and cataracts were compared in participants who did and did not take aspirin daily." | 3.67 | Aspirin use and chronic diseases: a cohort study of the elderly. ( Chao, A; Henderson, BE; Paganini-Hill, A; Ross, RK, 1989) |
| "Fifty-six patients who presented with non-steroidal anti-inflammatory drug-associated duodenal ulcers received maintenance treatment with ranitidine." | 3.67 | Ranitidine maintenance treatment of non-steroidal anti-inflammatory drug-induced duodenal ulceration. ( Penston, JG; Wormsley, KG, 1989) |
| " prevented formation of ulcers induced by serotonin, indomethacin, acetylsalicylic acid or stress (acute ulcer models), its effect being greater against gastric ulcers induced by serotonin." | 3.67 | Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103). ( Hoshina, K; Naruchi, T; Takeshita, T; Yamazaki, N, 1985) |
| "In a survey of the published evidence linking aspirin ingestion to gastric mucosal damage an attempt has been made to assess the role of aspirin in the pathogenesis of acute and chronic gastric haemorrhage and peptic ulceration." | 3.66 | Reappraisal of the effects of aspirin on the stomach. ( Rees, WD; Turnberg, LA, 1980) |
| "A comparison of aspirin and acetaminophen consumption in 346 matched pairs of patients with hematemesis and melena and general population control subjects has shown associations between intake of both drugs and bleeding." | 3.66 | Analgesic intake and the risk of acute upper gastrointestinal bleeding. ( Coggon, D; Langman, MJ; Spiegelhalter, D, 1983) |
| "An episode of severe small intestinal hemorrhage occurred in a cystic fibrosis patient having pancreatic insufficiency and receiving timed-release aspirin therapy for disabling hypertrophic pulmonary osteoarthropathy." | 3.66 | Possible hazard of timed-release aspirin in a patient with pancreatic insufficiency. ( Davis, PB; di Sant'Agnese, PA; Hubbard, VS, 1979) |
| "Aspirin-induced gastritis and gastrointestinal hemorrhage were reviewed and discussed on the basis of currently available literature." | 3.65 | Aspirin-induced gastritis and gastrointestinal bleeding. ( Gartner, AH, 1976) |
| " Taking aspirin is exceptional before rupture of esophageal varices." | 3.65 | [Clinical aspects and course of drug-induced upper digestive hemorrhage]. ( Benarous, JJ; Frexinos, J; Legrand, G; Pascal, JP; Ribet, A; Suduca, P; Tournut, R, 1976) |
| "The new antirheumatic agents, fenoprofen calcium, naproxen, and tolmetin sodium, are effective in the management of rheumatoid arthritis." | 3.65 | New antirheumatic agents: Fenoprofen calcium (Nalfon), naproxen (Naprosyn), and tolmetin sodium (Tolectin). ( Lewis, JR, 1977) |
| " There were five chronic alcoholics, one aspirin abuser, one severely burned patient, and one patient with sepsis." | 3.65 | Gastric devascularization: an alternate approach to the surgical treatment of massive, diffuse hemorrhage from gastritis. ( Aust, JB; McFee, AS; Rittenhouse, M, 1976) |
| "The effect of aspirin (acetylsalicylic acid) ingestion on occult gastrointestinal blood loss has been studied in patients with treated Addisonian pernicious anaemia and proved achlorhydria and in control patients able to secrete hydrochloric acid." | 3.65 | Influence of achlorhydria on aspirin-induced occult gastrointestinal blood loss: studies in Addisonian pernicious anaemia. ( John, DJ; McDermott, FT, 1970) |
| "The aspirin group was further divided into 3-day and 7-day aspirin groups." | 3.11 | Time of Resumption of Antiplatelet Drugs After Upper Gastrointestinal Hemorrhage. ( Fan, X; Jiao, L; Ma, H; Meng, X; Wang, J; Zhao, L, 2022) |
| "We examined new cancers diagnosed in relation to gastrointestinal or genitourinary bleeding among patients enrolled in the COMPASS trial (Cardiovascular Outcomes for People Using Anticoagulation Strategies) and determined the hazard of new cancer diagnosis after bleeding at these sites." | 2.90 | Bleeding and New Cancer Diagnosis in Patients With Atherosclerosis. ( Aboyans, V; Alings, M; Anand, SS; Avezum, A; Berkowitz, SD; Bhatt, DL; Bosch, J; Connolly, SJ; Cook-Bruns, N; Eikelboom, JW; Felix, C; Fox, KAA; Hart, RG; Maggioni, AP; Moayyedi, P; O'Donnell, M; Rydén, L; Shestakovska, O; Verhamme, P; Widimsky, P; Yusuf, S; Zhu, J, 2019) |
| " These drugs are well tolerated in the short term, but long-term treatment was associated with adverse events in observational studies." | 2.90 | Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin. ( Alings, M; Anand, SS; Avezum, A; Bhatt, DL; Bosch, J; Branch, KRH; Bruns, NC; Commerford, PJ; Connolly, SJ; Dagenais, GR; Dans, AL; Diaz, R; Dyal, L; Eikelboom, JW; Ertl, G; Felix, C; Fox, KAA; Guzik, TJ; Hart, RG; Hori, M; Kakkar, AK; Keltai, M; Kim, JH; Lanas, F; Leong, D; Lewis, BS; Liang, Y; Lonn, EM; Lopez-Jaramillo, P; Maggioni, AP; Metsarinne, KP; Moayyedi, P; Muehlhofer, E; O'Donnell, M; Parkhomenko, AN; Piegas, LS; Pogosova, N; Probstfield, J; Ryden, L; Shestakovska, O; Steg, PG; Störk, S; Tonkin, AM; Torp-Pedersen, C; Verhamme, PB; Vinereanu, D; Widimsky, P; Yusoff, K; Yusuf, S; Zhu, J, 2019) |
| "We aimed to explore whether risk of postoperative hemorrhage due to aspirin differs in the East and the West." | 2.82 | The risk of aspirin induced postoperative hemorrhage: a systematic review and meta-analysis. ( Chen, Y; Ding, Z; Han, C; Lin, R; Ling, X; Liu, J; Nie, C; Sheng, L, 2022) |
| "Randomized patients with available aspirin dosing information in COGENT (N = 3,752) were divided into "low-dose" (≤ 100 mg) and "high-dose" (>100 mg) aspirin groups." | 2.82 | Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy. ( Bhatt, DL; Cannon, CP; Cohen, M; Cryer, BL; Doros, G; Goldsmith, MA; Hsieh, WH; Laine, L; Lanas, A; Lapuerta, P; Liu, Y; Schnitzer, TJ; Shook, TL; Vaduganathan, M, 2016) |
| "Add-Aspirin is a phase III, multi-centre, double-blind, placebo-controlled randomised trial with four parallel cohorts." | 2.82 | ADD-ASPIRIN: A phase III, double-blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours. ( Berkman, L; Cafferty, FH; Cameron, D; Coyle, C; Gilbert, D; Gupta, S; Kynaston, H; Langley, RE; MacKenzie, M; Pramesh, CS; Ring, A; Rowley, S; Wilson, RH, 2016) |
| " The grade of gastric mucosal injuries was evaluated by esophagogastroduodenoscopy before and after dosing (on day 0 and day 14), and the grade of gastric mucosal injury was assessed according to the modified Lanza score." | 2.79 | A randomized, double-blind, placebo-controlled study of rebamipide for gastric mucosal injury taking aspirin with or without clopidogrel. ( Fukui, H; Hida, N; Hori, K; Miwa, H; Nakamura, S; Ogawa, T; Ohda, Y; Okugawa, T; Oshima, T; Tomita, T; Tozawa, K; Watari, J, 2014) |
| "Pantoprazole treatment does not impair the efficacy of dual antiplatelet therapy in patients with SAP after PCI." | 2.77 | Effects of pantoprazole on dual antiplatelet therapy in stable angina pectoris patients after percutaneous coronary intervention. ( Chmiel, A; Gąsior, Z; Gieszczyk, K; Haberka, M; Kunecki, M; Kyrcz-Krzemień, S; Lasota, B; Mizia, M; Mizia-Stec, K; Najda, J, 2012) |
| " Multiple gastroduodenal biopsies were performed during 2 esophagogastroduodenoscopy in subjects dosed with aspirin enteric-coated 81 mg once daily or clopidogrel 75 mg once daily." | 2.76 | Is gastroduodenal biopsy safe in patients receiving aspirin and clopidogrel?: a prospective, randomized study involving 630 biopsies. ( Aisenberg, J; Bamji, ND; Bodian, CA; Cohen, LB; Desai, JC; Dikman, AE; Harpaz, N; Kornacki, S; Miller, KM; Sanyal, S; von Althann, C; Whitson, MJ, 2011) |
| "Major bleeding was associated with a 3-fold increased risk of subsequent ischemic events (crude hazard ratio, 3." | 2.74 | Bleeding increases the risk of ischemic events in patients with peripheral arterial disease. ( Algra, A; Eikelboom, BC; Lawson, JA; Moll, FL; Tangelder, MJ; van Hattum, ES, 2009) |
| "The proportion of men still reporting hematospermia at 30 days after PB was 21." | 2.73 | Continuing or discontinuing low-dose aspirin before transrectal prostate biopsy: results of a prospective randomized trial. ( Barbone, F; De Maria, M; Giannarini, G; Manassero, F; Mogorovich, A; Morelli, G; Selli, C; Valent, F, 2007) |
| " However, questions remain regarding the benefit-risk relationship in certain settings since long-term use of ASA is not devoid of risk." | 2.72 | Primary Prevention of CVD with Aspirin: Benefits vs Risks. ( Brunton, S; Weisman, SM, 2021) |
| "Ibuprofen was statistically equivalent to paracetamol and better tolerated than aspirin (p <0." | 2.70 | Comparative tolerability of paracetamol, aspirin and ibuprofen for short-term analgesia in patients with musculoskeletal conditions: results in 4291 patients. ( Le Parc, JM; Moore, N; Schneid, H; Van Ganse, E; Verrière, F; Wall, R, 2002) |
| "Aspirin was most commonly used (43%)." | 2.69 | Non-steroidal anti-inflammatory drugs, Helicobacter pylori and bleeding gastric ulcer. ( Fock, KM; Khor, JL; Machin, D; Ng, TM; Sim, CS; Tan, AL; Teo, EK, 2000) |
| "Treatment with ibuprofen led to an increase of mean daily blood loss by + 0." | 2.68 | Gastrointestinal blood loss induced by three different non-steroidal anti-inflammatory drugs. ( Bidlingmaier, A; Hammermaier, A; Nagyiványi, P; Pabst, G; Waitzinger, J, 1995) |
| "Aspirin has proved useful in further reducing thromboembolic events when added to oral anticoagulants." | 2.68 | Low-intensity oral anticoagulation plus low-dose aspirin versus high-intensity oral anticoagulation alone: a randomized trial in patients with mechanical prosthetic heart valves. ( Fondevila, CG; Frontroth, J; Lazzari, MA; Meschengieser, SS; Santarelli, MT, 1997) |
| "The misoprostol/aspirin-treated group had significantly (P < 0." | 2.67 | Use of synthetic prostaglandin E1 (misoprostol) for prevention of aspirin-induced gastroduodenal ulceration in arthritic dogs. ( Boudrieau, RJ; Labato, MA; Matz, ME; Murtaugh, RJ, 1993) |
| "When enprostil was given in addition to aspirin, gastric blood loss was not significantly different from basal value." | 2.66 | Protective effect of low dose of enprostil against gastric blood loss induced by aspirin in man. ( Duchateau, A; Fierfort, E; Garbe, E; Joubert, M; Thiefin, G; Zeitoun, P, 1989) |
| " Flurbiprofen showed a linear dose-response relationship with respect to gastric injury and serum drug levels." | 2.66 | The effects of flurbiprofen, aspirin, cimetidine, and antacids on the gastric and duodenal mucosa of normal volunteers. An endoscopic and photographic study. ( Friedman, H; Lanza, FL; Royer, GL; Schwartz, JH; Seckman, CE; Stubbs, CM, 1989) |
| "When aspirin was ceased, blood loss returned more rapidly towards normal in the Ostoprin group (p less than 0." | 2.66 | Gastrointestinal blood loss from a new buffered aspirin (Ostoprin): measurement by radiochromium and Hemoquant techniques. ( Barraclough, D; Deacon, M; Lynch, NM; McHutchison, JG; St John, DJ; Young, GP, 1989) |
| "Indomethacin levels were significantly higher 2 h after Indocid-R than with indomethacin BP or indomethacin Continus." | 2.66 | Effect in man of aspirin, standard indomethacin, and sustained release indomethacin preparations on gastric bleeding. ( Hawkey, CJ; Poniatowska, TJ; Prichard, PJ; Ravenscroft, AT; Willars, JE, 1988) |
| " An initial dose-response study in 48 subjects showed that 200- and 400-mg doses of cimetidine conferred a sufficient reduction in gastric mucosal injury to warrant further study." | 2.66 | Reduction of endoscopically assessed acute aspirin-induced gastric mucosal injury with cimetidine. ( Chapman, RC; Kimmey, MB; Saunders, DR; Silverstein, FE, 1987) |
| " Unfortunately, they are often associated with dyspepsia, and this troublesome side-effect is a limitation to their chronic use by many patients." | 2.66 | Non-steroidal anti-inflammatory drugs (NSAIDs) cause gastrointestinal intolerance and major bleeding--or do they? ( Tenenbaum, J, 1987) |
| "In aspirin treated subjects both mucosal generation and luminal release of prostaglandins and thromboxane B2 were greatly suppressed although sucralfate treatment did not influence these prostaglandins in spite of the reduction in mucosal damage." | 2.66 | Double blind controlled study on the effect of sucralfate on gastric prostaglandin formation and microbleeding in normal and aspirin treated man. ( Konturek, SJ; Kopp, B; Kwiecień, N; Obtułowicz, W; Oleksy, J, 1986) |
| "Aspirin alone was used as a positive control." | 2.66 | Effects of aspirin and an aspirin-acetaminophen combination on the gastric mucosa in normal subjects. A double-blind endoscopic study. ( Graham, DY; Smith, JL, 1985) |
| " Plasma concentrations of tilcotil showed that the drug's half-life was approximately 50 hours, compatible with once daily dosage, and steady state concentrations on multiple dosing were reached after 10 to 12 days." | 2.65 | Gastro-intestinal blood loss with high dose tilcotil (Ro 12-0068) and aspirin: an open crossover clinical trial and pharmacokinetic assessment in normal volunteers. ( Bird, HA; Galloway, DB; Lowe, JR; McEvoy, M; Pickup, ME; Taylor, P; Wright, V, 1983) |
| " Following an initial dose-response study, a double-blind crossover trial was performed using pretreatment with placebo or with 10-micrograms doses of 15-R-15 methyl prostaglandin E2 for 24 h before treatment with aspirin." | 2.65 | Prevention of acute aspirin-induced gastric mucosal injury by 15-R-15 methyl prostaglandin E2: an endoscopic study. ( Bergman, D; Feld, AD; Gilbert, DA; Sanford, RL; Saunders, DR; Silverstein, FE; Surawicz, CM; Washington, P; Weinberg, CR, 1984) |
| "01) differences in microbleeding between subjects given aspirin and those given either dosage of fenbufen or placebo." | 2.65 | Comparative study of gastrointestinal microbleeding caused by aspirin, fenbufen, and placebo. ( Lebel, E; Lussier, A; Tétreault, L, 1983) |
| " Bioavailability studies carried out on 10 healthy male volunteers demonstrated that absorption from the enteric-coated pellet capsules was sustained and complete." | 2.65 | Enteric-coated pelletized aspirin. Gastrointestinal blood loss and bioavailability. ( Fleming, A; Graham, G; Portek, I, 1981) |
| " The ideal dosage to obtain a serum salicylate level of 20 mg/100 ml seems to lie between 3 and 4 g of salsalate a day." | 2.65 | Comparison of serum salicylate levels and gastro-intestinal blood loss between salsalate (Disalcid)and other forms of salicylates. ( Mielants, H; Verbruggen, G; Veys, EM, 1981) |
| " The investigation was carried out as a two-part, randomized cross-over trial, and with a test dosage of either 1 g X 4 or 2 g X 2 per day, given to 10 and 14 male students, respectively, during two 5-day periods separated by a one week interval." | 2.65 | Gastrointestinal blood loss caused by controlled-release and conventional acetylsalicylic acid tablets. ( Brandslund, I; Klitgaard, NA; Rask, H, 1979) |
| " The bioavailability of the salicylate preparations was studied in seven of the 12 patients." | 2.64 | The effects of enteric coating of aspirin tablets on occult gastrointestinal blood loss. ( Champion, GD; Corrigan, AB; Day, RO; Graham, GG; Haski, A; Hewson, J; Howe, GB; Paull, PD, 1977) |
| ") combined with aspirin." | 2.64 | Comparision of low dose heparin and low dose heparin combined with aspirin in prevention of deep vein thrombosis after total hip replacement. ( Blery, M; Flicoteaux, H; Honnart, F; Jean, N; Judet, T; Kher, A; Pasteyer, J, 1977) |
| "Aspirin was associated with a higher risk of major bleeding (RR: 1." | 2.61 | Aspirin for Primary Prevention of Cardiovascular Events. ( Abbott, JD; Abdelaziz, HK; Aronow, HD; Bhatt, DL; Kon, DLC; Megaly, M; Mehta, JL; Pothineni, NVK; Potluri, R; Roberts, DH; Saad, M; Saleh, M, 2019) |
| "Performance in patients with cerebral ischemia was poor." | 2.53 | Prediction models for intracranial hemorrhage or major bleeding in patients on antiplatelet therapy: a systematic review and external validation study. ( Algra, A; Greving, JP; Hilkens, NA, 2016) |
| "Aspirin was associated with increased bleeding risks when combined with non-steroidal anti-inflammatory drugs, clopidogrel and selective serotonin reuptake inhibitors compared with monotherapy." | 2.53 | Bleeding Risk with Long-Term Low-Dose Aspirin: A Systematic Review of Observational Studies. ( García Rodríguez, LA; Hennekens, CH; Lanas, A; Martín-Pérez, M; Rothwell, PM, 2016) |
| "Aspirin has been shown to lower the incidence and the mortality of vascular disease and cancer but its wider adoption appears to be seriously impeded by concerns about gastrointestinal (GI) bleeding." | 2.53 | Systematic Review and Meta-Analysis of Randomised Trials to Ascertain Fatal Gastrointestinal Bleeding Events Attributable to Preventive Low-Dose Aspirin: No Evidence of Increased Risk. ( Chia, JW; Dolwani, S; Elwood, PC; Galante, J; Graziano, JM; Kelson, M; Lanas, A; Longley, M; Morgan, G; Morris, D; Phillips, CJ; Pickering, J; Roberts, SE; Soon, SS; Steward, W; Weightman, AL, 2016) |
| " Although administration of antiplatelet agents has been confirmed to be one of the major approaches for secondary prevention of noncardioembolic stroke, the short-term or long-term use of aspirin plus clopidogrel for secondary stroke prevention remains to be controversial." | 2.52 | Dual antiplatelet therapy with clopidogrel and aspirin for secondary stroke prevention. ( Chen, W; Wang, Y, 2015) |
| "Treatment of celecoxib with a proton pump inhibitor is safer than treatment with nonselective NSAID and a proton pump inhibitor in high risk gastrointestinal and cardiovascular patients who mostly also take acetylsalicylic acid." | 2.52 | [Gastrointestinal bleeding]. ( Lanas, Á, 2015) |
| "Aspirin/NANSAIDs use was strongly and consistently associated with an increased risk of colonic diverticular bleeding." | 2.50 | Aspirin and non-aspirin NSAIDs increase risk of colonic diverticular bleeding: a systematic review and meta-analysis. ( Corley, DA; Igarashi, M; Koike, J; Mine, T; Nakahara, F; Nakajima, T; Suauki, T; Yuhara, H, 2014) |
| "Aspirin reduced reported colorectal cancer (CRC) incidence (OR 0." | 2.49 | Aspirin for prophylactic use in the primary prevention of cardiovascular disease and cancer: a systematic review and overview of reviews. ( Clarke, A; Connock, M; Freeman, K; Grove, A; Gurung, B; Gurung, T; Johnson, S; Kandala, NB; Morrow, S; Sutcliffe, P, 2013) |
| "Aspirin has been recommended for primary prevention of cardiovascular disease (CVD) and cancer, but overall benefits are unclear." | 2.49 | Aspirin in primary prevention of cardiovascular disease and cancer: a systematic review of the balance of evidence from reviews of randomized trials. ( Clarke, A; Connock, M; Freeman, K; Grove, A; Gurung, B; Gurung, T; Johnson, S; Morrow, S; Ngianga-Bakwin, K; Stranges, S; Sutcliffe, P, 2013) |
| "Aspirin was discontinued and pantoprazole was started, with resolution of the bleeding." | 2.49 | Reinitiating aspirin therapy for primary prevention of cardiovascular events in a patient post-aspirin-induced upper gastrointestinal bleed: a case report and review of literature. ( Adly, G; Plakogiannis, R, 2013) |
| " Despite substantial clinical heterogeneity across the studies, including types of H2 blockers, dosing of ASA and underlying conditions, no statistical heterogeneity was observed." | 2.48 | Histamine H2 receptor antagonists for decreasing gastrointestinal harms in adults using acetylsalicylic acid: systematic review and meta-analysis. ( Al-Omran, M; Alateeq, A; Mamdani, M; Straus, SE; Tashkandi, M; Tricco, AC, 2012) |
| " In order to achieve the desired results and, as with all medications, PPIs should always be used appropriately taking care never to exceed correct dosage and duration." | 2.47 | Proton pump inhibitors in rheumatic diseases: clinical practice, drug interactions, bone fractures and risk of infections. ( Ferraccioli, GF; Gremese, E; Laria, A; Zoli, A, 2011) |
| " Furthermore, there is growing evidence that long-term use of aspirin decreases the risk of colorectal cancer, even at low doses." | 2.47 | Gastrointestinal effects of aspirin. ( Lanas, A; Sostres, C, 2011) |
| "Aspirin has traditionally been used." | 2.46 | Gastrointestinal bleed with clopidogrel and aspirin. ( Choudhary, S; Joshi, R; Kohli, V; Sibal, A, 2010) |
| "Aspirin is a very useful medication for the prevention of cardiovascular thrombotic events in patients with or those at risk for cardiovascular disease (CVD)." | 2.42 | Cardioprotective effects and gastrointestinal risks of aspirin: maintaining the delicate balance. ( Kimmey, MB, 2004) |
| "Aspirin reduced all-cause mortality by 18%." | 2.41 | Evaluation of the benefits and risks of low-dose aspirin in the secondary prevention of cardiovascular and cerebrovascular events. ( Graham, DY; Weisman, SM, 2002) |
| "She developed aplastic anemia seven weeks after initiation of ticlopidine." | 2.41 | Ticlopidine-induced aplastic anemia and quick recovery with G-CSF: case report and literature review. ( Ammash, Z; Dabajah, B; Mourad, FH; Nasrallah, A; Taher, A, 2000) |
| "Nonaspirin NSAIDs inhibit cyclooxygenase reversibly and, therefore, the duration of their action depends on specific drug dose, serum level, and half-life." | 2.39 | Effects of nonsteroidal antiinflammatory drugs on platelet function and systemic hemostasis. ( Schafer, AI, 1995) |
| "Thirty-six randomized control trials of aspirin compared with another dosage of aspirin or with placebo." | 2.39 | Efficacy and safety of different aspirin dosages on vascular diseases in high-risk patients. A metaregression analysis. ( Cappelleri, JC; Chalmers, TC; Kupelnick, B; Lau, J, 1995) |
| "Zenker's diverticulum is an unusual site of origin for clinically significant upper gastrointestinal hemorrhage." | 2.39 | Massive bleeding from a Zenker's diverticulum: case report and review of the literature. ( Dyck, WP; Kensing, KP; Korompai, F; White, JG, 1994) |
| " Chronic use is associated with uncomplicated gastric ulcer (but not clearly with uncomplicated duodenal ulcer) and with presentation with haematemesis and melaena." | 2.39 | Review article: aspirin and gastrointestinal bleeding. ( Hawkey, CJ, 1994) |
| " There is disagreement over the optimal dosage to prevent a stroke: earlier studies considered > or = 975 mg ASS per day, sometimes in combination with other substances, while more recently, lower dosages of about 300 mg per day or even as low as < or = 100 mg per day have been proposed." | 2.39 | [Aspirin dosage for prevention of cerebral infarct: arguments for low dosage]. ( Hennerici, MG; Meairs, S, 1995) |
| "Nabumetone is a nonacidic nonsteroidal antiinflammatory drug (NSAID) that is effective and appears to cause minimal NSAID gastropathy." | 2.38 | Upper gastrointestinal safety with nabumetone. ( Roth, SH, 1992) |
| " Some of the newer NSAIDs seem at normal dosage to be far less damaging than traditional ASA or indomethacin." | 2.37 | Gastroduodenal damage due to drugs, alcohol and smoking. ( Domschke, S; Domschke, W, 1984) |
| " This dose-response effect, evident in both endoscopic and microbleeding studies done after acute or short-term aspirin administration, is also associated with the risk of developing chronic gastric ulcer." | 2.37 | Aspirin and the stomach. ( Graham, DY; Smith, JL, 1986) |
| "Acetaminophen is an effective antipyretic and analgesic with few side effects that is toxic only in massive overdose." | 2.36 | Use of antipyretic analgesics in the pediatric patient. ( Gladtke, E, 1983) |
| "Chronic gastric ulcer is linked to aspirin intake in patients with rheumatic disease, and epidemiologically in all heavy aspirin users; paradoxically, in only one epidemiologic study was a significant association found between acetaminophen intake and chronic gastric ulcer." | 2.36 | Gastrointestinal effects of antipyretic analgesics. ( Ivey, KJ, 1983) |
| " Papillitis of the renal system may result from a comparable dosage of aspirin compound mediates with phenacetin." | 2.36 | Harmful effects of "aspirin compounds". ( Najjar, TA, 1977) |
| "lansoprazole was 0." | 1.91 | Cost-Effectiveness of Vonoprazan Compared With Proton Pump Inhibitors in Patients Taking Low-Dose Aspirin for Secondary Prevention of Cardiovascular Events in Japan. ( Deguchi, H; Fernandez, J; Igarashi, A; Ishii, M; Kawai, T; Suzuki, M; Tsujita, K, 2023) |
| "Eupatilin was associated with a reduced risk of SB bleeding in both aspirin users and those with concomitant use of acid suppressants." | 1.91 | Association between eupatilin and reduction in small bowel bleeding in aspirin users and aspirin plus acid suppressant users. ( Ahn, HJ; Lee, HS; Lim, YJ; Nam, JH; Oh, DJ, 2023) |
| "A total of 597 patients with gastric neoplasms treated with ESD between January 2010 and June 2017 were enrolled." | 1.51 | Feasibility of gastric endoscopic submucosal dissection with continuous low-dose aspirin for patients receiving dual antiplatelet therapy. ( Amano, Y; Harada, H; Hayasaka, K; Katsuyama, Y; Murakami, D; Nagasaka, T; Nakahara, R; Sagami, R; Suehiro, S; Ujihara, T, 2019) |
| "Aspirin was reported by about 11% patients, as being twice as used in men (11." | 1.48 | Epidemiology of non-steroidal anti-inflammatory drugs consumption in Spain. The MCC-Spain study. ( Alonso-Molero, J; Altzibar, JM; Amiano, P; Aragonés, N; Barricarte, A; Benavente, Y; Capelo, R; Castaño-Vinyals, G; Dávila-Batista, V; de Pedro, M; Dierssen-Sotos, T; Etxeberria, J; Fernández-Tardón, G; Fernández-Villa, T; Gómez-Acebo, I; Huerta, JM; Kogevinas, M; Llorca, J; Marcos-Gragera, R; Palazuelos-Calderón, C; Peiró, R; Pérez-Gómez, B; Pollán, M; Salcedo-Bellido, I; Tardón, A, 2018) |
| "The cumulative recurrence rate at 1 year was 15%." | 1.46 | Analysis of risk factors for colonic diverticular bleeding and recurrence. ( Fukui, H; Miwa, H; Ohda, Y; Oshima, T; Taki, M; Taniguchi, Y; Tomita, T; Tozawa, K; Watari, J, 2017) |
| "Aspirin users were found to be at increased risk for major gastrointestinal bleeding." | 1.46 | Should This Patient Receive Aspirin?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. ( Burns, RB; Graham, K; Reynolds, EE; Sawhney, MS, 2017) |
| "Retroperitoneal hematoma is a rare complication of psoas catheter placement, typically occurring several days after placement and in the setting of anticoagulation." | 1.43 | Acute Retroperitoneal Hematoma After Psoas Catheter Placement in a Patient with Myeloproliferative Thrombocytosis and Aspirin Therapy. ( Duncan, CM; Kopp, SL; Warner, NS, 2016) |
| "Few large studies have evaluated the adverse events associated with therapeutic colonoscopy for colorectal neoplasia, including bleeding and bowel perforation." | 1.43 | Factors predicting adverse events associated with therapeutic colonoscopy for colorectal neoplasia: a retrospective nationwide study in Japan. ( Fushimi, K; Hirata, Y; Koike, K; Matsui, H; Niikura, R; Yamada, A; Yasunaga, H, 2016) |
| "Recurrence of hepatocellular carcinoma (HCC) with unsatisfactory survival is common after surgical resection." | 1.43 | Antiplatelet Therapy is Associated with a Better Prognosis for Patients with Hepatitis B Virus-Related Hepatocellular Carcinoma after Liver Resection. ( Chao, Y; Chen, CC; Chen, TJ; Hu, YW; Huang, YH; Huo, TI; Lee, PC; Lin, HC; Liu, CJ; Su, CW; Wu, JC; Yeh, CM, 2016) |
| "To assess the consequences of switching aspirin dosage from 100 mg/d to 40 mg/d on cardiovascular benefit, bleeding risk and platelet aggregation in very elderly patients." | 1.43 | [Dose-response of aspirin on platelet function in very elderly patients]. ( Fan, Y; Feng, XR; Liu, F; Liu, ML; Tian, QP, 2016) |
| "The long-term recurrence of lower gastrointestinal bleeding (LGIB) and associated mortality have not been studied extensively." | 1.42 | Recurrence and mortality among patients hospitalized for acute lower gastrointestinal bleeding. ( Akiyama, J; Aoki, T; Kishida, Y; Mizokami, M; Nagata, N; Niikura, R; Sakurai, T; Sekine, K; Shimbo, T; Tanaka, S; Uemura, N; Watanabe, K; Yanase, M; Yokoi, C, 2015) |
| " Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database." | 1.42 | Analysis of the Interaction between Clopidogrel, Aspirin, and Proton Pump Inhibitors Using the FDA Adverse Event Reporting System Database. ( Abe, J; Hara, H; Kinosada, Y; Miyamura, N; Nakamura, M; Nishibata, Y; Sekiya, Y; Suzuki, H; Suzuki, Y; Tsuchiya, T; Umetsu, R; Uranishi, H, 2015) |
| "Oral anticoagulation is the recommended treatment for stroke prevention in patients with atrial fibrillation." | 1.40 | Atrial fibrillation patients do not benefit from acetylsalicylic acid. ( Friberg, L; Själander, A; Själander, S; Svensson, PJ, 2014) |
| "Meckel's diverticulum is one of the best indications for VE." | 1.40 | [Meckel's diverticulum detected by virtual enteroscopy in a patient with nonsteroidal anti-inflammatory drug-induced enteropathy]. ( Kikuyama, M; Kurokami, T; Yoshikawa, T, 2014) |
| " Even a 12-hour separation of dosing does not appear to prevent drug interactions between omeprazole and clopidogrel." | 1.40 | Proton-pump inhibitors in patients requiring antiplatelet therapy: new FDA labeling. ( Chilton, R; Johnson, DA; Liker, HR, 2014) |
| " Drug exposure was determined based on prescriptions of nsNSAIDs, COX-2 inhibitors, or low-dose aspirin, alone and in combination with other drugs that affect the risk of UGIB." | 1.40 | Risk of upper gastrointestinal bleeding from different drug combinations. ( Coloma, PM; de Ridder, M; Gini, R; Herings, R; Kuipers, EJ; Masclee, GM; Mazzaglia, G; Pedersen, L; Picelli, G; Romio, S; Schuemie, MJ; Scotti, L; Sturkenboom, MC; Valkhoff, VE; van der Lei, J, 2014) |
| "Rebleeding was diagnosed when the previously treated lesion bled again within 30 days of the initial episode." | 1.40 | Rebleeding after initial endoscopic hemostasis in peptic ulcer disease. ( Hong, MJ; Jin, CJ; Kim, JH; Lee, SY; Park, HS; Shim, CS; Sung, IK, 2014) |
| "The aspirin was stopped immediately." | 1.39 | Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis). ( Alghamdi, M; Alhussaini, H; Almalki, AS; Alokaily, FA, 2013) |
| "The risk of postoperative hemorrhage following gastric ESD was higher in patients with antithrombotic therapy than in those without that therapy." | 1.39 | The postoperative bleeding rate and its risk factors in patients on antithrombotic therapy who undergo gastric endoscopic submucosal dissection. ( Edogawa, S; Harada, S; Higuchi, K; Kojima, Y; Ota, K; Takeuchi, T; Tokioka, S; Umegaki, E, 2013) |
| "Patients who underwent ESD for early gastric neoplasms at the National Cancer Center Hospital, Korea, between November 2008 and January 2011 were enrolled." | 1.38 | Aspirin use and bleeding risk after endoscopic submucosal dissection in patients with gastric neoplasms. ( Cho, SJ; Choi, IJ; Kim, CG; Kim, HJ; Kim, YW; Kwak, MH; Lee, JH; Lee, JY; Nam, BH; Ryu, KW, 2012) |
| "Once gastrointestinal hemorrhage has occurred, several studies have indicated the need to implement simpler prognostic scales than those used today." | 1.38 | [Gastrointestinal bleeding associated with NSAIDs, antiplatelet therapy and anticoagulant agent]. ( Lanas, A, 2012) |
| "This study evaluated the risk of upper gastrointestinal bleeding (UGIB) associated with use of low-dose acetylsalicylic acid (ASA) alone and in combination with other gastrotoxic medications." | 1.37 | Risk of upper gastrointestinal bleeding with low-dose acetylsalicylic acid alone and in combination with clopidogrel and other medications. ( García Rodríguez, LA; Hernández-Díaz, S; Johansson, S; Lin, KJ, 2011) |
| "Aspirin was held, on average, 3 days both pre- and post-polypectomy." | 1.37 | Optimal timing of anticoagulation pre- and post-colonoscopy with polypectomy. ( Heyrosa, MG; Khubchandani, IT; Thekkeurumbil, SV, 2011) |
| " Similar dose-response relationships were observed among short-term users (≤5 years; P(trend)<." | 1.37 | Long-term use of aspirin and the risk of gastrointestinal bleeding. ( Chan, AT; Ho, WW; Huang, ES; Lee, SS; Strate, LL, 2011) |
| "Pretreatment with melatonin or tryptophan remarkably reduced ASA induced gastric lesions and microbleeding." | 1.36 | Role of melatonin in mucosal gastroprotection against aspirin-induced gastric lesions in humans. ( Bielanski, W; Celinski, K; Cichoz-Lach, H; Konturek, PC; Konturek, SJ; Reiter, RJ; Slomka, M, 2010) |
| "Aspirin use was reported in 50% of patients: 68." | 1.36 | Aspirin use in elderly women receiving medication therapy management services. ( Cooke, CE; Lee, HY; Tong, YP; Xing, S, 2010) |
| " In 199 patients treated with DAT alone (control group) and 103 patients treated with rabeprazole plus DAT (rabeprazole group), we examined the incidences of GI bleeding and major adverse cardiac events (MACE) including stent thrombosis." | 1.36 | [Efficacy and safety of concomitant use of rabeprazole during dual-antiplatelet therapy with clopidogrel and aspirin after drug-eluting stent implantation: a retrospective cohort study]. ( Chubachi, H; Ikee, R; Miyasaka, Y; Saito, S; Yasu, T, 2010) |
| "Aspirin use was determined at baseline and one year later." | 1.35 | Consistent aspirin use associated with improved arteriovenous fistula survival among incident hemodialysis patients in the dialysis outcomes and practice patterns study. ( Akizawa, T; Bragg-Gresham, JL; Elder, SJ; Fukuhara, S; Hasegawa, T; Hugh, RC; Jadoul, M; Pisoni, RL; Port, FK; Yamazaki, S, 2008) |
| "Celecoxib without ASA was less likely than NS-NSAID without ASA to be associated with GI hospitalization [hazard ratio (HR) 0." | 1.34 | Hospitalization for gastrointestinal bleeding associated with non-steroidal anti-inflammatory drugs among elderly patients using low-dose aspirin: a retrospective cohort study. ( Bardou, M; Barkun, AN; Dasgupta, K; Ghosn, J; Rahme, E; Toubouti, Y, 2007) |
| " However, drug-drug interactions may lead to a greatly increased risk of gastrointestinal bleeding when these drugs are combined." | 1.34 | Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding. ( Brophy, JM; Delaney, JA; Opatrny, L; Suissa, S, 2007) |
| "Aspirin is known to produce severe adverse gastrointestinal effects, such as bleeding and perforation." | 1.33 | Minidose aspirin and gastrointestinal bleeding--a retrospective, case-control study in hospitalized patients. ( Eliakim, R; Fishman, M; Hershkovici, M; Niv, Y; Sapoznikov, B; Vilkin, A, 2005) |
| " This study suggests that short-term NG intubation is relatively safe and may be beneficial and indicated for acute GI bleeding after recent MI." | 1.33 | Safety and efficacy of nasogastric intubation for gastrointestinal bleeding after myocardial infarction: an analysis of 125 patients at two tertiary cardiac referral hospitals. ( Cappell, MS, 2005) |
| " The mean aspirin dosage was 81 mg/day over a period of 6-288 weeks (mean: 86." | 1.33 | [Significance of the stool occult blood test in patients with thrombotic disease under treatment with low dose aspirin]. ( Hayashi, S; Wakizaka, A, 2005) |
| "In addition, diverticular bleeding in the elderly was highly associated with intake of Aspirin." | 1.33 | [Epidemiology of gastrointestinal bleeding in the elderly]. ( Bertschinger, P; Bühler, H; Geyer, M; Stamenic, I, 2006) |
| "We compared the gastric toxic effect of aspirin (ASA) in both normal and diabetic rats, with that of NCX-4016, a derivative of ASA with nitric oxide (NO) releasing moiety." | 1.31 | Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats. ( Fujita, A; Takeuchi, K; Tashima, K; Umeda, M, 2000) |
| "Aspirin was associated with higher risk of upper gastrointestinal bleeding: OR=1." | 1.31 | [Upper gastrointestinal bleeding in patients treated by low-dose aspirin]. ( Amouretti, M; Capet, C; Colin, R; Czernichow, P; Dupas, JL; Goria, O; Gouérou, H; Herman, H; Hochain, P, 2001) |
| " However, a 13-fold increase in the risk of UGIB occurs with long-term use of oral anticoagulants and NSAIDs." | 1.30 | Effect of combined anticoagulation and low-dose aspirin treatment on upper gastrointestinal bleeding. ( Cloutier, DA; Schatz, RA; Spinks, TJ; Strum, WB; Teirstein, PS; Younossi, ZM, 1997) |
| "Acute bleeding from oesophageal varices is a major complication of cirrhosis of the liver." | 1.30 | Anti-inflammatory drugs and variceal bleeding: a case-control study. ( Beauchant, M; Becker, MC; Bernard, P; De Lédinghen, V; Fourdan, O; Gourlaouen, A; Heresbach, D; Ingrand, P; Liebaert-Bories, MP; Nousbaum, JB; Ribard, D; Silvain, C, 1999) |
| "If aspirin was administered subcutaneously or intrajejunally for 20 days, neither adaptation nor inflammation of the gastric mucosa was observed." | 1.29 | Adaptation of rat gastric mucosa to aspirin requires mucosal contact. ( Bell, CJ; McKnight, GW; Wallace, JL, 1995) |
| "Acute lower gastrointestinal hemorrhage in a 17-year-old boy was caused by a Meckel's diverticulum 1 day after ingestion of 500 mg acetylsalicylic acid." | 1.29 | Preoperative diagnosis of Meckel's diverticulum by pertechnetate scan and laparoscopic resection. ( Decurtins, M; Heinzelmann, M; Himmelmann, A; Largiadér, F; Schlumpf, R; Schöb, O, 1994) |
| "When myocardial infarction is due to coronary embolism from endocarditic valves standard thrombolysis regimes should be avoided." | 1.29 | Acute coronary embolism complicating aortic valve endocarditis treated with streptokinase and aspirin. A case report. ( Connolly, DL; Crowley, JJ; Dardas, PS; Kenny, A; Petch, MC, 1994) |
| "Consecutive patients with upper gastrointestinal hemorrhage evaluated by a gastroenterology consultative service at a large inner-city hospital from August 1, 1990 to July 31, 1992 were identified." | 1.29 | Striking prevalence of over-the-counter nonsteroidal anti-inflammatory drug use in patients with upper gastrointestinal hemorrhage. ( Cotsonis, G; Shalek, KA; Wilcox, CM, 1994) |
| "of rioprostil were 61 and 52% lower, respectively, than the mean severity score in the vehicle-treated group." | 1.28 | Rioprostil prevents aspirin-induced fecal blood loss in dogs. Correlation of Hemoquant (Hb) with endoscopic findings. ( Fernandez, JA; Katz, LB; Schwartz, S; Shriver, DA, 1989) |
| "Aspirin (100 mg/day)-treated and nontreated rats were fed for 7 days, a mixed diet of 2." | 1.28 | Fatty acid changes in liver choline and ethanolamine glycerophospholipids in aspirin-treated rats fed linoleate, gamma-linolenate and fish oil. ( Horrobin, DF; Huang, YS; Simmons, V; Watanabe, Y, 1989) |
| "Aspirin was given orally in a single daily dose of 200 mg/kg for two days." | 1.28 | Acute effects of fever, fasting and aspirin on infant rat gastric mucosa. ( Chang, MH; Chen, PH; Chuang, YH; Liu, YC, 1989) |
| " The reduction in gastric bleeding with the 50-microgram dosage of misoprostol was directly related to the reduction in acid secretion." | 1.27 | Effect of synthetic prostaglandin E1 analog on aspirin-induced gastric bleeding and secretion. ( Hunt, JN; Jiang, CL; Kessler, L; Smith, JL, 1983) |
| "Thrombocytopenia was induced in rabbits by the intraperitoneal injection of busulphan dissolved in polyethylene glycol (PEG) at a dose of 60 mg/kg." | 1.27 | A platelet release defect induced by aspirin or penicillin G does not increase gastrointestinal blood loss in thrombocytopenic rabbits. ( Giles, AR; Greenwood, P; Tinlin, S, 1984) |
| " The prolonged protection against aspirin-induced bleeding achieved with twice daily dosing with ranitidine has clinical potential in the management of patients taking anti-inflammatory drugs." | 1.27 | Prophylaxis of aspirin-induced gastric mucosal bleeding with ranitidine. ( Hawkey, CJ; Marshall, S; Somerville, KW, 1988) |
| " Seemingly, cimetidine given at an oral dosage of 7." | 1.27 | Effect of cimetidine on aspirin-induced gastric hemorrhage in dogs. ( Boulay, JP; Klausner, JS; Lipowitz, AJ, 1986) |
| "Diclofenac (Voltarol) has no effect on carbohydrate metabolism, insulin levels or tolbutamide metabolism, nor does it enhance the effect of tolbutamide, biguanide or glibenclamide." | 1.26 | Diclofenac sodium (Voltarol): drug interactions and special studies. ( Fowler, PD, 1979) |
| "One hundred consecutive cases of upper gastrointestinal hemorrhage were studied clinically, radiologically and endoscopically." | 1.26 | Upper gastrointestinal hemorrhage clinical, radiological and endoscopic correlation of 100 consecutive cases. ( Dinoso, VP; Lorber, SH; Meshkinpour, H, 1976) |
| " However, because of the inability to augment iron absorption to compensate for blood loss, it would be inadvisable for the patient with a partial gastrectomy to take a high dosage of aspirin for long periods of time, unless aspirin-induced blood loss is measured and shown to be very low." | 1.25 | Role of occult blood loss in anaemia after partial gastrectomy. ( Baird, IM; Nasser, SS; St John, DJ, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 546 (41.18) | 18.7374 |
| 1990's | 113 (8.52) | 18.2507 |
| 2000's | 213 (16.06) | 29.6817 |
| 2010's | 373 (28.13) | 24.3611 |
| 2020's | 81 (6.11) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, H | 1 |
| Fordice, MW | 1 |
| Greenwald, RB | 1 |
| Hannah, J | 1 |
| Jacobs, A | 1 |
| Ruyle, WV | 1 |
| Walford, GL | 1 |
| Shen, TY | 1 |
| Joseph, P | 1 |
| Roshandel, G | 1 |
| Gao, P | 1 |
| Pais, P | 1 |
| Lonn, E | 1 |
| Xavier, D | 1 |
| Avezum, A | 4 |
| Zhu, J | 4 |
| Liu, L | 2 |
| Sliwa, K | 1 |
| Gamra, H | 1 |
| Bangdiwala, SI | 1 |
| Teo, K | 1 |
| Diaz, R | 3 |
| Dans, A | 2 |
| Lopez-Jaramillo, P | 3 |
| Prabhakaran, D | 1 |
| Castellano, JM | 1 |
| Fuster, V | 2 |
| Rodgers, A | 1 |
| Huffman, MD | 1 |
| Bosch, J | 4 |
| Dagenais, GR | 3 |
| Malekzadeh, R | 1 |
| Yusuf, S | 4 |
| Peng, D | 1 |
| Zhang, M | 1 |
| Han, Y | 4 |
| Liao, Z | 2 |
| Li, Y | 3 |
| Zhao, X | 1 |
| Ma, S | 2 |
| Bao, D | 2 |
| Qiu, M | 1 |
| Deng, J | 2 |
| Wang, J | 3 |
| Qu, P | 1 |
| Jiang, C | 1 |
| Jia, S | 1 |
| Yang, S | 1 |
| Ru, L | 1 |
| Feng, J | 1 |
| Gao, W | 1 |
| Huang, Y | 1 |
| Tao, L | 1 |
| Yang, K | 1 |
| Wang, X | 5 |
| Zhang, W | 1 |
| Wang, B | 1 |
| Yang, Y | 2 |
| Li, J | 4 |
| Sheng, J | 1 |
| Ma, Y | 1 |
| Cui, M | 1 |
| Li, Z | 3 |
| Stone, GW | 2 |
| Huynh, K | 1 |
| Okada, T | 1 |
| Mikamo, T | 1 |
| Nakashima, A | 1 |
| Yanagitani, A | 1 |
| Tanaka, K | 1 |
| Isomoto, H | 1 |
| Miilunpohja, S | 1 |
| Jyrkkä, J | 1 |
| Kärkkäinen, JM | 1 |
| Kastarinen, H | 1 |
| Heikkinen, M | 1 |
| Paajanen, H | 1 |
| Rantanen, T | 1 |
| Hartikainen, J | 1 |
| Mallah, N | 1 |
| Zapata-Cachafeiro, M | 2 |
| Aguirre, C | 1 |
| Ibarra-García, E | 1 |
| Palacios-Zabalza, I | 1 |
| Macías-García, F | 1 |
| Piñeiro-Lamas, M | 1 |
| Ibáñez, L | 3 |
| Vidal, X | 4 |
| Vendrell, L | 4 |
| Martin-Arias, L | 1 |
| Sáinz-Gil, M | 1 |
| Velasco-González, V | 1 |
| Bacariza-Cortiñas, M | 1 |
| Salgado, A | 1 |
| Estany-Gestal, A | 1 |
| Figueiras, A | 1 |
| Shami, JJP | 1 |
| Zhao, J | 2 |
| Pathadka, S | 1 |
| Wan, EYF | 1 |
| Blais, JE | 1 |
| Vora, P | 2 |
| Soriano-Gabarró, M | 3 |
| Cheung, KS | 3 |
| Leung, WK | 5 |
| Wong, ICK | 2 |
| Chan, EW | 3 |
| Marmo, R | 2 |
| Occhipinti, V | 1 |
| Zullo, A | 3 |
| Soncini, M | 1 |
| Roberts, G | 1 |
| Baker, M | 1 |
| Leiblich, H | 1 |
| Paulose, M | 1 |
| Pegoli, M | 1 |
| Panagopoulos, L | 1 |
| Schiller, C | 1 |
| Suppiah, V | 1 |
| Seifert, LL | 1 |
| Schindler, P | 1 |
| Sturm, L | 1 |
| Gu, W | 1 |
| Seifert, QE | 1 |
| Weller, JF | 1 |
| Jansen, C | 1 |
| Praktiknjo, M | 1 |
| Meyer, C | 1 |
| Schoster, M | 1 |
| Wilms, C | 1 |
| Maschmeier, M | 1 |
| Schmidt, HH | 1 |
| Masthoff, M | 1 |
| Köhler, M | 1 |
| Schultheiss, M | 1 |
| Huber, JP | 1 |
| Bettinger, D | 1 |
| Trebicka, J | 1 |
| Wildgruber, M | 1 |
| Heinzow, H | 1 |
| Ayonrinde, OT | 2 |
| Walldorf, N | 1 |
| Chan, N | 1 |
| Foo, NY | 1 |
| Kulkarni, T | 1 |
| Olynyk, JK | 1 |
| Sanfilippo, FM | 2 |
| Dehmer, SP | 2 |
| O'Keefe, LR | 1 |
| Evans, CV | 2 |
| Guirguis-Blake, JM | 2 |
| Perdue, LA | 1 |
| Maciosek, MV | 2 |
| Kishi, Y | 1 |
| Aota, Y | 1 |
| Horie, Y | 2 |
| Sutoh, A | 1 |
| Moriyama, M | 1 |
| Okabe, M | 1 |
| Iguchi, T | 1 |
| Yokouchi, Y | 1 |
| Gotoh, A | 1 |
| Maetani, I | 2 |
| Wang, M | 1 |
| Yu, H | 1 |
| Gong, D | 1 |
| Liu, X | 1 |
| Forgerini, M | 3 |
| Urbano, G | 3 |
| De Nadai, TR | 3 |
| Zanelli, CF | 1 |
| Valentini, SR | 1 |
| Mastroianni, PC | 2 |
| Nguyen, TNM | 1 |
| Sha, S | 1 |
| Chen, LJ | 1 |
| Holleczek, B | 1 |
| Brenner, H | 2 |
| Schöttker, B | 1 |
| Kurlander, JE | 1 |
| Barnes, GD | 2 |
| Fisher, A | 1 |
| Gonzalez, JJ | 1 |
| Helminski, D | 1 |
| Saini, SD | 4 |
| Sengupta, N | 2 |
| Yang, YX | 1 |
| Scheiman, J | 6 |
| Laine, L | 18 |
| Tan, JL | 1 |
| Sidhu-Brar, S | 1 |
| Woodman, R | 1 |
| Chinnaratha, MA | 1 |
| Zhu, Y | 2 |
| Zhao, Q | 1 |
| Yu, L | 1 |
| Horiuchi, Y | 1 |
| Ishiyama, A | 1 |
| Tsuchida, T | 1 |
| Yoshimizu, S | 1 |
| Hirasawa, T | 1 |
| Fujisaki, J | 1 |
| Yoshio, T | 2 |
| Ma, H | 2 |
| Fan, X | 1 |
| Jiao, L | 1 |
| Meng, X | 1 |
| Zhao, L | 1 |
| Nammour, T | 1 |
| El Jamal, L | 1 |
| Hosni, MN | 1 |
| Tamim, H | 1 |
| Kerbage, A | 1 |
| Hashash, JG | 1 |
| Shaib, YH | 1 |
| Daniel, F | 1 |
| Francis, F | 1 |
| Mourad, FH | 2 |
| Soweid, A | 1 |
| Sharara, AI | 1 |
| Makki, M | 1 |
| Rockey, DC | 5 |
| Barada, K | 3 |
| Huang, HY | 1 |
| Lin, SY | 1 |
| Katz, AJ | 1 |
| Sheu, JJ | 1 |
| Lin, FJ | 1 |
| Wang, CC | 1 |
| Wu, CH | 1 |
| Ishii, M | 2 |
| Kawai, T | 3 |
| Tsujita, K | 1 |
| Igarashi, A | 1 |
| Suzuki, M | 1 |
| Deguchi, H | 1 |
| Fernandez, J | 1 |
| Schultz, C | 1 |
| Elshafei, MN | 2 |
| Imam, Y | 2 |
| Alsaud, AE | 2 |
| Chandra, P | 1 |
| Parray, A | 1 |
| Abdelmoneim, MS | 1 |
| Obeidat, K | 2 |
| Saeid, R | 2 |
| Ali, M | 2 |
| Ayadathil, R | 1 |
| Mohamed, MFH | 2 |
| Abdallah, IM | 2 |
| Mohammed, S | 1 |
| Akhtar, N | 1 |
| Danjuma, MI | 2 |
| Ling, X | 1 |
| Lin, R | 1 |
| Chen, Y | 3 |
| Nie, C | 1 |
| Sheng, L | 1 |
| Liu, J | 2 |
| Han, C | 1 |
| Ding, Z | 1 |
| Li, DK | 5 |
| Ong, SY | 3 |
| Hughes, ML | 3 |
| Hung, KW | 3 |
| Agarwal, R | 3 |
| Alexis, J | 3 |
| Damianos, J | 3 |
| Sharma, S | 4 |
| Pires, J | 3 |
| Nanna, M | 3 |
| Miura, Y | 1 |
| Tsuji, Y | 1 |
| Hatta, W | 1 |
| Yabuuchi, Y | 1 |
| Hoteya, S | 1 |
| Kikuchi, D | 1 |
| Tsuji, S | 1 |
| Nagami, Y | 1 |
| Hikichi, T | 1 |
| Kobayashi, M | 1 |
| Morita, Y | 1 |
| Sumiyoshi, T | 1 |
| Iguchi, M | 1 |
| Tomida, H | 1 |
| Inoue, T | 1 |
| Mikami, T | 1 |
| Hasatani, K | 1 |
| Nishikawa, J | 1 |
| Matsumura, T | 2 |
| Nebiki, H | 1 |
| Nakamatsu, D | 1 |
| Ohnita, K | 1 |
| Suzuki, H | 2 |
| Ueyama, H | 1 |
| Hayashi, Y | 1 |
| Sugimoto, M | 2 |
| Yamaguchi, S | 1 |
| Michida, T | 1 |
| Yada, T | 1 |
| Asahina, Y | 1 |
| Narasaka, T | 1 |
| Kuribayashi, S | 1 |
| Kiyotoki, S | 1 |
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| Batah, SS | 1 |
| Fabro, AT | 1 |
| De Carvalho Mastroianni, P | 1 |
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| Harper, C | 1 |
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| Herrington, W | 1 |
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| Stevens, W | 1 |
| Wallendszus, K | 1 |
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| Landray, MJ | 1 |
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| Pepine, CJ | 1 |
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| Farrehi, PM | 1 |
| Knowlton, KU | 1 |
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| Harrington, RA | 2 |
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| Chen, YC | 1 |
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| Eikelboom, JW | 4 |
| Connolly, SJ | 3 |
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| Alings, M | 3 |
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| Bhatt, DL | 15 |
| Cook-Bruns, N | 1 |
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| Tanaka, A | 3 |
| Tseng, ZF | 1 |
| Hsu, PI | 6 |
| Peng, NJ | 1 |
| Kao, SS | 1 |
| Tsay, FW | 2 |
| Cheng, JS | 1 |
| Chen, WC | 3 |
| Tsai, KF | 1 |
| Tang, SY | 1 |
| Chuah, SK | 3 |
| Shie, CB | 1 |
| Hirsch, C | 1 |
| Hui, VW | 1 |
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| Wong, VW | 2 |
| Tse, YK | 3 |
| Chan, HL | 2 |
| Lui, GC | 1 |
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| Guo, CG | 2 |
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| Wu, JT | 1 |
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| Law, SYK | 1 |
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| Murao, T | 4 |
| Handa, O | 1 |
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| Tsujimoto, H | 1 |
| Hirata, Y | 5 |
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| Collins, R | 1 |
| Hazleman, BL | 1 |
| Damman, HG | 1 |
| Marinis, E | 1 |
| Pabst, MA | 1 |
| Davis, A | 1 |
| Lussier, Y | 1 |
| Friedman, H | 1 |
| Seckman, CE | 1 |
| Schwartz, JH | 1 |
| Stubbs, CM | 1 |
| Lynch, NM | 1 |
| McHutchison, JG | 1 |
| Young, GP | 1 |
| Deacon, M | 1 |
| Barraclough, D | 1 |
| Lorbach, M | 1 |
| Biour, M | 1 |
| Blanquart, A | 1 |
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| Amiot, X | 1 |
| Levy, VG | 1 |
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| Cheymol, G | 1 |
| Uribe, A | 1 |
| Johansson, C | 1 |
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| Rubio, C | 1 |
| Lanza, F | 1 |
| Panagides, J | 1 |
| Salom, IL | 1 |
| Kopp, B | 2 |
| Saffiotti, O | 1 |
| Mosca, S | 1 |
| Di Cesare, D | 1 |
| Esposito, F | 1 |
| Somerville, KW | 3 |
| Marshall, S | 1 |
| Drummond, R | 1 |
| Bianchi Porro, G | 1 |
| Pace, F | 1 |
| Simpson, G | 1 |
| Stiel, D | 1 |
| Ellard, KT | 1 |
| Hills, LJ | 1 |
| Brooks, PM | 1 |
| Myers, BM | 1 |
| Ryan, JR | 1 |
| Vargas, R | 1 |
| Clay, GA | 1 |
| McMahon, FG | 1 |
| Gullikson, GW | 1 |
| Anglin, CP | 1 |
| Kessler, LK | 1 |
| Smeach, S | 1 |
| Bauer, RF | 1 |
| Dajani, EZ | 2 |
| Rogers, C | 1 |
| Brown, A | 1 |
| Szabo, S | 1 |
| Levy, M | 2 |
| Miller, DR | 1 |
| Siskind, V | 1 |
| Schwingl, P | 1 |
| Rosenberg, L | 1 |
| Strom, B | 1 |
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| Spjut, HJ | 1 |
| Torres, E | 1 |
| Poniatowska, TJ | 1 |
| Willars, JE | 1 |
| Ravenscroft, AT | 1 |
| Fujii, A | 1 |
| Kuboyama, N | 1 |
| Namiki, Y | 1 |
| Tamura, T | 1 |
| Butt, JH | 1 |
| Barthel, JS | 1 |
| Moore, RA | 1 |
| Chapman, RC | 1 |
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| Obtułwicz, W | 1 |
| Semble, EL | 1 |
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| Giercksky, KE | 2 |
| Revhaug, A | 1 |
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| Stalnikowicz, R | 1 |
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| Rooney, PJ | 2 |
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| Casteels-Van Daele, M | 2 |
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| Weiss, HJ | 2 |
| Aledort, LM | 1 |
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| Williamson, JM | 1 |
| Goldberg, A | 1 |
| Wares, E | 1 |
| Bouchier, IA | 1 |
| Williams, HS | 1 |
| Dobbing, J | 1 |
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| Hazell, K | 1 |
| Vogel, G | 1 |
| Krusch, G | 1 |
| Marchetti, M | 1 |
| Vignati, E | 1 |
| Nicolis, FB | 1 |
| Davis, SL | 1 |
| Hadley, RA | 1 |
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| Godquin, B | 1 |
| Guillou, N | 1 |
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| Edelson, J | 2 |
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| Hambly, CK | 1 |
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| Dick-Smith, JB | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| COmparison of Mono- Versus Dual antiPlatelet Therapy During 6-12 Months After New Generation Drug Eluting Stent Implantation for Prevention of Gastrointestinal Injury Evaluated by Ankon Magnetically Controlled Capsule Endoscopy[NCT03198741] | Phase 4 | 783 participants (Actual) | Interventional | 2017-07-13 | Completed | ||
| Evaluation of the Efficacy of Different Duration of a Proton Pump Inhibitor in the Prevention of Upper Gastrointestinal Mucosal Injury in Patients Taking 12-month Dual Antiplatelet Therapy After Coronary Artery Bypass Grafting[NCT03908593] | Phase 4 | 232 participants (Anticipated) | Interventional | 2019-10-14 | Active, not recruiting | ||
| An Investigation Into The Impact Of Enteric Coated Of Aspirin In Patients With Newly Diagnosed Ischemic Stroke. Non-randomized Interventional Controlled Clinical Trial.[NCT04330872] | Phase 4 | 42 participants (Actual) | Interventional | 2019-08-26 | Completed | ||
| A Study of Cardiovascular Events iN Diabetes - A Randomized 2x2 Factorial Study of Aspirin Versus Placebo, and of Omega-3 Fatty Acid Supplementation Versus Placebo, for Primary Prevention of Cardiovascular Events in People With Diabetes[NCT00135226] | Phase 4 | 15,480 participants (Actual) | Interventional | 2005-03-31 | Active, not recruiting | ||
| A Randomized Controlled Trial of Rivaroxaban for the Prevention of Major Cardiovascular Events in Patients With Coronary or Peripheral Artery Disease (COMPASS - Cardiovascular OutcoMes for People Using Anticoagulation StrategieS).[NCT01776424] | Phase 3 | 27,395 participants (Actual) | Interventional | 2013-02-28 | Completed | ||
| HELicobacter Pylori Screening to Prevent Gastrointestinal Bleeding in Patients With Acute Myocardial Infarction Trial Based on the SWEDEHEART Registry (HELP-SWEDEHEART)[NCT05024864] | 22,000 participants (Anticipated) | Interventional | 2021-11-17 | Recruiting | |||
| Aspirin in Reducing Events in the Elderly[NCT01038583] | 19,114 participants (Actual) | Observational | 2010-01-31 | Active, not recruiting | |||
| Major Bleeding Risk Associated With Antithrombotics : The SACHA (Surveillance Des Accidents Hémorragiques Graves Sous Antithrombotiques) Study[NCT02886533] | 6,484 participants (Actual) | Observational | 2013-01-01 | Completed | |||
| Comparison of Efficacy and Safety Between Aspirin and Clopidogrel in the Atrial Fibrillation With Low or Moderate Stroke Risk[NCT02960126] | Phase 3 | 1,500 participants (Anticipated) | Interventional | 2016-11-30 | Not yet recruiting | ||
| A Phase 3, Multicenter, Randomized, Double-blind, AG-1749-controlled, Parallel-group, Comparison Study to Evaluate the Efficacy and Safety of TAK-438 (10 mg or 20 mg, Orally, Once Daily) for the Prevention of Recurrent Gastric or Duodenal Ulcers During Lo[NCT01452763] | Phase 3 | 621 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| A Phase 3, Multicenter, Single-blind, AG-1749-controlled, Parallel-group, Long-term Extension Study to Evaluate the Safety and Efficacy of TAK-438 (10 mg or 20 mg, Orally, Once Daily) for the Prevention of Recurrent Gastric or Duodenal Ulcers During Long-[NCT01456247] | Phase 3 | 439 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| Plaque Erosion: A New in Vivo Diagnosis and Paradigm Shift in the Treatment of Patients With Acute Coronary Syndrome[NCT02041650] | Phase 4 | 250 participants (Anticipated) | Interventional | 2014-08-31 | Completed | ||
| Endoscopic Diagnosis, Treatment and Prognosis of Acute Nonvariceal Upper Gastrointestinal Bleeding in Nanchang, Jiangxi Province, China.[NCT04895904] | 3,200 participants (Actual) | Observational | 2014-09-01 | Completed | |||
| Factors Predicting the Need for Endoscopic Intervention in Non-variceal Upper Gastrointestinal Bleeding[NCT05979025] | 262 participants (Actual) | Observational | 2022-08-11 | Completed | |||
| Correlation Between Bleeding Complication and Treatment Failure of DOAC and Its Predictions Based on Cipherome's Pharmacogenomic Technology[NCT04597593] | 200 participants (Actual) | Observational | 2020-10-07 | Completed | |||
| Efficacy and Safety of Clopidogrel for Primary Prevention in Patients With Subclinical Coronary Atherosclerosis Identified on Imaging[NCT05845489] | Phase 4 | 9,930 participants (Anticipated) | Interventional | 2023-03-09 | Recruiting | ||
| Aspirin Discontinuation After Left Atrial Appendage Occlusion in Atrial Fibrillation[NCT03821883] | 1,120 participants (Anticipated) | Interventional | 2020-06-01 | Recruiting | |||
| A Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Parallel Group Study to Assess the Efficacy (Reduction of Cardiovascular Disease Events) and Safety of 100 mg Enteric-Coated Acetylsalicylic Acid in Patients at Moderate Risk of Cardiovascular [NCT00501059] | Phase 3 | 12,546 participants (Actual) | Interventional | 2007-07-05 | Completed | ||
| The Impact of Aspirin Dose Modification on the Innate Immune Response - Will Lower Dose Aspirin Therapy Reduce the Response to Endotoxin[NCT03869268] | Phase 4 | 72 participants (Actual) | Interventional | 2019-04-24 | Completed | ||
| Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial[NCT00991029] | Phase 3 | 4,881 participants (Actual) | Interventional | 2010-05-28 | Terminated (stopped due to The trial was halted by the DSMB.) | ||
| The Efficacy and Safety of Proton Pump Inhibitor ( in Patients With Moderate Bleeding Risk and Coronary Artery Disease Undergoing Percutaneous Coronary: A Randomised, Open ,Compared With Control[NCT05820048] | Phase 4 | 300 participants (Anticipated) | Interventional | 2023-05-01 | Not yet recruiting | ||
| Multicenter Randomized, Double-blind, Placebo-controlled, Clinical Trial of Acetylsalicylic Acid in the Prevention of Severe SARS-CoV2 Pneumonia in Hospitalised Patients (Asperum)[NCT04808895] | Phase 3 | 204 participants (Anticipated) | Interventional | 2021-04-01 | Not yet recruiting | ||
| Clinical Study Evaluating the Gastroprotective Effect of Carvedilol in Patients With Ischemic Heart Disease on Aspirin Therapy[NCT05553717] | 66 participants (Anticipated) | Interventional | 2022-10-31 | Not yet recruiting | |||
| Vitamin K Supplementation to Improve INR Stability in Patients on Hemodialysis Taking Warfarin for Atrial Fibrillation[NCT02324686] | Phase 2 | 3 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Women's Health Study of Low-dose Aspirin and Vitamin E in Apparently Healthy Women[NCT00000479] | Phase 3 | 39,876 participants (Actual) | Interventional | 1992-09-30 | Completed | ||
| Transient Electrocardiogram Assessment in Stroke Evaluation[NCT03301662] | 100 participants (Anticipated) | Observational | 2017-10-09 | Not yet recruiting | |||
| Pilot Intervention to Improve the Transition From Hospital to Home[NCT01431846] | 19 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| A Randomized, Double-Blind, Double-Dummy, Parallel Group, Phase 3 Efficacy and Safety Study of CGT-2168 Compared With Clopidogrel to Reduce Upper Gastrointestinal Events Including Bleeding and Symptomatic Ulcer Disease[NCT00557921] | Phase 3 | 5,000 participants (Anticipated) | Interventional | 2007-12-31 | Terminated (stopped due to Terminated by Sponsor) | ||
| Sclerotherapy With Polidocanol Foam in the Treatment of First, Second and Third-Grade Hemorrhoidal Disease in Patients With Liver Cirrhosis: A Prospective, Cohort Trial[NCT05807425] | Phase 2/Phase 3 | 40 participants (Anticipated) | Interventional | 2023-03-31 | Recruiting | ||
| Video Capsule Endoscopy for Lesion Localization and Diagnosis in Patients With Severe Hematochezia[NCT03616041] | 50 participants (Anticipated) | Observational | 2021-02-10 | Recruiting | |||
| Nurses' Health Study (Cardiovascular Component)[NCT00005152] | 121,700 participants (Actual) | Observational | 1980-08-31 | Active, not recruiting | |||
| Optimal Dose of Proton Pump Inhibitors Following an Upper Gastrointestinal Bleed[NCT02235311] | 3 participants (Actual) | Interventional | 2014-10-31 | Terminated (stopped due to Difficulty recruiting and consenting participants) | |||
| Comparative Effectiveness of Fecal Immunochemical Tests With Optical Colonoscopy[NCT03264898] | 3,600 participants (Anticipated) | Observational | 2017-10-02 | Recruiting | |||
| Validation of Advanced Colorectal Neoplasm Risk Categories in Screening Colonoscopy and Identification of Biomarkers in a Prospective Cohort in Mexico.[NCT05661292] | 2,000 participants (Anticipated) | Observational | 2019-08-01 | Recruiting | |||
| Phase IV Study of Aspirin and Clopidogrel Therapy Tailored by Functional Thrombocyte Examination (PFA-100, LTA and VerifyNOW) in Acute Myocardial Infarction[NCT01381185] | Phase 4 | 154 participants (Actual) | Interventional | 2011-05-31 | Completed | ||
| Efficacy of H2 Receptor Antagonist in Prevention of Thienopyridine-related Peptic Ulcer[NCT02418312] | 228 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
| Pantoprazole Versus Famotidine for the Prevention of Recurrent Peptic Ulcers in Thienopyridine Users - a Double-blind Randomized Controlled Trial[NCT02551744] | 101 participants (Actual) | Interventional | 2012-07-31 | Completed | |||
| [NCT00153725] | 156 participants | Interventional | 2003-02-28 | Completed | |||
| Screening of Gastrointestinal Tract Bleeding Causes Among Chronic Renal Failure Patients in Assuit University in a Single Study Center[NCT04491669] | 100 participants (Anticipated) | Observational | 2020-10-01 | Not yet recruiting | |||
| A Prospective Evaluation of an Anesthesia Protocol to Reduce Post-operative and Post-discharge Nausea and Vomiting in a High Risk Orthognathic Surgery Population[NCT01592708] | 233 participants (Actual) | Interventional | 2012-06-30 | Completed | |||
| Erythromycin Versus Gastric Lavage to Improve Quality of Endoscopic Examination in Patients With Upper Gastrointestinal Bleeding. A Prospective Randomized Trial.[NCT01716572] | Phase 3 | 122 participants (Anticipated) | Interventional | 2012-02-29 | Active, not recruiting | ||
| Famotidine Compared With Esomeprazole in the Prevention of Ulcer Complications in Patients With Acute Coronary Syndrome or Myocardial Infarction[NCT00683111] | Phase 4 | 500 participants (Anticipated) | Interventional | 2008-07-31 | Completed | ||
| Comparison of Small Colorectal Polyp Removal Using Cold Endoscopic Mucosal Resection With Hot Endoscopic Mucosal Resection: a Pilot Study[NCT03000868] | 0 participants (Actual) | Interventional | 2016-12-01 | Withdrawn (stopped due to No participants were enrolled.) | |||
| WilL LOWer Dose Aspirin be More Effective Following ACS? (WILLOW-ACS)[NCT02741817] | Phase 4 | 20 participants (Actual) | Interventional | 2016-06-26 | Completed | ||
| Sclerotherapy With Polidocanol Foam In The Management Of First, Second And Third-Grade Hemorrhoidal Disease In Patients With Bleeding Disorders: A Prospective Cohort Study[NCT04188171] | Phase 2/Phase 3 | 150 participants (Anticipated) | Interventional | 2018-08-01 | Active, not recruiting | ||
| To Investigate Post-procedure Hemorrhage and Cardiovascular Events in Taiwanese Patients Who Continue or Discontinue Low-Dose Aspirin Before Transrectal Prostate Biopsy: a Prospective Randomized Trial[NCT02744937] | Phase 4 | 150 participants (Anticipated) | Interventional | 2016-04-30 | Not yet recruiting | ||
| The Role of Routine Placement of Nasogastric Tube in Patients With Suspected Upper Gastrointestinal Hemorrhage[NCT00689754] | 282 participants (Actual) | Interventional | 2008-01-31 | Completed | |||
| Does Acetaminophen Potentiate the Gastroduodenal Mucosal Injury of Aspirin? A Prospective, Randomized, Pilot Study.[NCT00594867] | Phase 4 | 94 participants (Actual) | Interventional | 2006-12-31 | Completed | ||
| Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)[NCT02409680] | 11,976 participants (Actual) | Interventional | 2016-03-23 | Completed | |||
| Aspirin Impact on Platelet Reactivity in Acute Coronary Syndrome Patients on Novel P2Y12 Inhibitors Therapy[NCT02049762] | Phase 4 | 29 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| A Randomized, Double-Blind, Multicenter Study to Evaluate the Tolerability and Effectiveness of Etoricoxib 90 mg q.d. vs. Diclofenac Sodium 50 mg t.i.d. in Patients With Osteoarthritis[NCT00092703] | Phase 3 | 6,000 participants | Interventional | 2002-06-27 | Completed | ||
| A 12-Week, Randomized, Placebo- and Active-Comparator-Controlled, Parallel-Group, Double-Blind Study to Assess the Safety and Efficacy of Etoricoxib 30 mg Versus Ibuprofen 2400 mg in Patients With Osteoarthritis (Study 1)[NCT00269191] | Phase 3 | 528 participants (Actual) | Interventional | 2003-02-05 | Completed | ||
| A Randomized, Double-Blind, Active-Comparator-Controlled, Parallel-Group Study to Evaluate the Safety of Etoricoxib in Patients With Osteoarthritis or Rheumatoid Arthritis[NCT00250445] | Phase 3 | 23,498 participants (Actual) | Interventional | 2003-01-31 | Completed | ||
| Aspirin Versus Aspirin + ClopidogRel as Antithrombotic Treatment Following Transcatheter Aortic Valve Implantation With the Edwards Valve. A Randomized Study (the ARTE Trial)[NCT02640794] | Phase 4 | 222 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Data-driven Quality Improvement in Primary Care: Cluster Randomised Controlled Trial to Test the Effectiveness of a Multifaceted Intervention in Reducing High Risk Prescribing of Non-steroidal Anti-inflammatory Drugs and Antiplatelet Agents[NCT01425502] | 33 participants (Actual) | Interventional | 2012-09-30 | Completed | |||
| Aspirin Versus Aspirin + ClopidogRel as Antithrombotic Treatment Following Transcatheter Aortic Valve Implantation With the Edwards SAPIEN XT Valve. A Randomized Pilot Study (the ARTE Trial)[NCT01559298] | Phase 4 | 178 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| Beijing Tiantan Hospital,Capital Medical University.[NCT02317445] | 472 participants (Actual) | Observational | 2008-01-31 | Completed | |||
| Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy[NCT01605903] | Phase 2 | 741 participants (Actual) | Interventional | 2012-05-03 | Completed | ||
| Gastrointestinal Ulceration in Patients on Dual Antiplatelet Therapy After Percutaneous Coronary Intervention[NCT00413309] | 30 participants (Anticipated) | Interventional | 2006-04-30 | Completed | |||
| The Comparison of Effect Between Salsalate and Placebo in Osteoarthritis With Nonalcoholic Fatty Liver Disease: Investigator Initiated Randomized Placebo-controlled Double-blind, Pilot Study[NCT03222206] | Phase 4 | 34 participants (Actual) | Interventional | 2017-11-08 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Secondary efficacy assessments of aspirin involve intention-to-treat comparisons during the scheduled treatment period among all randomized participants on the first occurrence of:~Any incident gastrointestinal (GI) tract cancer (i.e. any GI cancer excluding pancreas and hepatobiliary), overall and after exclusion of the first three years of follow-up." (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 157 |
| Placebo Aspirin | 158 |
"Secondary efficacy assessments involve intention-to-treat comparisons among all randomized participants of allocation to aspirin versus placebo and, separately, of omega-3 versus placebo on the first occurrence of the expanded vascular endpoint of SVE or revascularization (including coronary and non-coronary revascularizations)." (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 833 |
| Placebo Aspirin | 936 |
| Omega-3 | 882 |
| Placebo Omega-3 | 887 |
"Incidence of fatal or non-fatal cancers. Any cancer excludes non-fatal non-melanoma skin cancer and non-fatal recurrence of a cancer that had occurred before randomization.~A single participant may have had multiple cancers." (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 897 |
| Placebo Aspirin | 887 |
| Omega-3 | 894 |
| Placebo Omega-3 | 890 |
Includes fatal and non-fatal events. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Omega-3 | 166 |
| Placebo Omega-3 | 135 |
Includes fatal and non-fatal cancers. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 97 |
| Placebo Aspirin | 96 |
| Omega-3 | 103 |
| Placebo Omega-3 | 90 |
Includes fatal and non-fatal renal, bladder, prostate, gynaecological and other GU cancers (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 332 |
| Placebo Aspirin | 294 |
| Omega-3 | 323 |
| Placebo Omega-3 | 303 |
Includes fatal and non-fatal cancers. Includes leukaemia and lymphoma. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 88 |
| Placebo Aspirin | 86 |
| Omega-3 | 94 |
| Placebo Omega-3 | 80 |
Includes fatal and non-fatal melanomas. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 50 |
| Placebo Aspirin | 59 |
| Omega-3 | 55 |
| Placebo Omega-3 | 54 |
Includes fatal and non-fatal events, excludes atrial fibrillation. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Omega-3 | 83 |
| Placebo Omega-3 | 99 |
Includes fatal and non-fatal cancers not included elsewhere (where the type of cancer is known). (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 25 |
| Placebo Aspirin | 30 |
| Omega-3 | 23 |
| Placebo Omega-3 | 32 |
Includes fatal and non-fatal cancers. Excludes cancers reported in the gastrointestinal tract category (see secondary outcome measure #4), and includes hepatobiliary and pancreatic cancers. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 87 |
| Placebo Aspirin | 82 |
Includes fatal and non-fatal cancers. Includes lung and larynx cancer. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 101 |
| Placebo Aspirin | 103 |
| Omega-3 | 104 |
| Placebo Omega-3 | 100 |
Includes fatal and non-fatal cancers of unknown type. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 26 |
| Placebo Aspirin | 31 |
| Omega-3 | 25 |
| Placebo Omega-3 | 32 |
Fatal 'All stroke' events include deaths from: Haemorrhagic stroke (Intracerebral haemorrhage; Subarachnoid haemorrhage); Non-haemorrhagic stroke (Cerebral infarction; Stroke not specified as haemorrhage or infarction). (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 38 |
| Placebo Aspirin | 34 |
| Omega-3 | 35 |
| Placebo Omega-3 | 37 |
'All-cause mortality' includes all recorded deaths. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 748 |
| Placebo Aspirin | 792 |
| Omega-3 | 752 |
| Placebo Omega-3 | 788 |
Fatal 'Cancer' events include any death attributed to cancer. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 309 |
| Placebo Aspirin | 315 |
| Omega-3 | 305 |
| Placebo Omega-3 | 319 |
Fatal 'Coronary' events include deaths from: Acute MI and other CHD (unspecified Acute ischaemic heart disease; Atherosclerotic heart disease; Ischaemic cardiomyopathy; unspecified Chronic ischaemic heart disease). (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 105 |
| Placebo Aspirin | 122 |
| Omega-3 | 100 |
| Placebo Omega-3 | 127 |
Fatal 'External cause' events include deaths from: Injury; Fracture; Self harm; and Medical and surgical complications (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 18 |
| Placebo Aspirin | 21 |
| Omega-3 | 17 |
| Placebo Omega-3 | 22 |
Fatal 'Other medical' events include deaths from: Non-vascular medical causes (excluding cancer and respiratory, including Fatal GI bleed or perforation); and deaths from Renal disease and Diabetes. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 126 |
| Placebo Aspirin | 157 |
| Omega-3 | 158 |
| Placebo Omega-3 | 125 |
Fatal 'Other vascular' events include deaths from: Heart failure (excluding ischaemic cardiomyopathy); Other vascular death (excluding stroke; and Cardiac death (excluding CHD). (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 67 |
| Placebo Aspirin | 70 |
| Omega-3 | 61 |
| Placebo Omega-3 | 76 |
Fatal 'Respiratory' events include any death attributed to respiratory causes. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 82 |
| Placebo Aspirin | 69 |
| Omega-3 | 73 |
| Placebo Omega-3 | 78 |
Any death for which the cause is not known. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 3 |
| Placebo Aspirin | 4 |
| Omega-3 | 3 |
| Placebo Omega-3 | 4 |
"The primary safety assessments involve intention-to-treat comparisons among all randomized patients of allocation to aspirin versus placebo on the first occurrence of any major bleed, defined as:~any confirmed intracranial hemorrhage (including intracerebral, subarachnoid, subdural or any other intracranial hemorrhage); or~sight-threatening eye bleeding; or~any other serious bleeding episode." (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 314 |
| Placebo Aspirin | 245 |
"The primary efficacy assessments involve intention-to-treat comparisons among all randomized participants of allocation to aspirin versus placebo and, separately, of omega-3 fatty acids versus placebo on the first occurrence of any Serious Vascular Event (SVE), defined as:~non-fatal myocardial infarction; or~non-fatal stroke (excluding confirmed intracranial hemorrhage) or TIA; or~vascular death excluding confirmed intracranial hemorrhage (defined as International Classification of Diseases 10th revision [ICD-10] I00-52 or I63-99, i.e. excluding subarachnoid hemorrhage [I60], intracerebral hemorrhage [I61], and other non-traumatic intracranial hemorrhage [I62])." (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Aspirin | 658 |
| Placebo Aspirin | 743 |
| Omega-3 | 689 |
| Placebo Omega-3 | 712 |
Count of participants and time from randomization to death by all cause were evaluated. Hazard ratios were calculated and reported as statistical analysis. (NCT01776424)
Timeframe: For each participants, death by any cause after randomization up until the global rivaroxaban/aspirin outcomes cut-off date (06 FEB 2017) was considered. The mean time in follow-up until that date was 702 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Rivaroxaban 2.5mg + Aspirin 100mg | 313 |
| Rivaroxaban 5mg + Aspirin Placebo | 366 |
| Rivaroxaban Placebo + Aspirin 100mg | 378 |
Count of participants from COMPASS LTOLE initiation visit to death by all cause were evaluated. LTOLE: long-term open-lable extension (NCT01776424)
Timeframe: For each participants, death by any cause after COMPASS LTOLE initiation visit up until the the last LTOLE part contact date was considered. The mean time in follow-up until that date was 428 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| LTOLE Part: Rivaroxaban 2.5mg + Aspirin 100mg | 282 |
Count of participants and time from randomization to the first occurrence of MI, ischemic stroke, ALI, or CV death were evaluated. Hazard ratios were calculated and reported as statistical analysis. (NCT01776424)
Timeframe: For each participant, the first occurrence of MI, ischemic stroke, ALI, or CV death after randomization up until the global rivaroxaban/aspirin outcomes cut-off date (06 FEB 2017) was considered. The mean time in follow-up until that date was 702 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Rivaroxaban 2.5mg + Aspirin 100mg | 389 |
| Rivaroxaban 5mg + Aspirin Placebo | 453 |
| Rivaroxaban Placebo + Aspirin 100mg | 516 |
Count of participants and time from randomization to the first occurrence of MI, ischemic stroke, ALI, or CHD death were evaluated. Hazard ratios were calculated and reported as statistical analysis. (NCT01776424)
Timeframe: For each participant, the first occurrence of MI, ALI, or CHD death after randomization up until the global rivaroxaban/aspirin outcomes cut-off date (06 FEB 2017) was considered. The mean time in follow-up until that date was 702 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Rivaroxaban 2.5mg + Aspirin 100mg | 329 |
| Rivaroxaban 5mg + Aspirin Placebo | 397 |
| Rivaroxaban Placebo + Aspirin 100mg | 450 |
Count of participants and time from randomization to the first occurrence of the composite primary efficacy outcome, MI, stroke, or CV death were evaluated. Hazard ratios were calculated and reported as statistical analysis. (NCT01776424)
Timeframe: For each participant, the first occurrence of the composite primary efficacy outcome after randomization up until the global rivaroxaban/aspirin outcomes cut-off date (06 FEB 2017) was considered. The mean time in follow-up until that date was 702 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Rivaroxaban 2.5mg + Aspirin 100mg | 379 |
| Rivaroxaban 5mg + Aspirin Placebo | 448 |
| Rivaroxaban Placebo + Aspirin 100mg | 496 |
Count of participants from COMPASS LTOLE initiation visit to the first occurrence of the composite primary efficacy outcome, MI, stroke, or CV death were evaluated. LTOLE: long-term open-lable extension (NCT01776424)
Timeframe: For each participant, the first occurrence of the composite primary efficacy outcome after from COMPASS LTOLE initiation visit up until last LTOLE part contact date was considered. The mean time in follow-up was 428 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| LTOLE Part: Rivaroxaban 2.5mg + Aspirin 100mg | 353 |
"Modified ISTH major bleeding is defined as: i) Fatal bleeding, or ii) Symptomatic bleeding in a critical area or organ, such as intraarticular, intracranial, intramuscular with compartment syndrome, intraocular, intraspinal, liver, pancreas, pericardial, respiratory, retroperitoneal, adrenal gland or kidney; or bleeding into the surgical site requiring reoperation, or iii) Bleeding leading to hospitalization (major bleeding also includes presentation to an acute care facility with discharge on the same day).~Count of participants and time from randomization to the first occurrence of the primary safety outcome major bleeding were evaluated. Hazard ratios were calculated and reported as statistical analysis." (NCT01776424)
Timeframe: For each participant, the first occurrence of modified ISTH major bleeding after randomization up until the global rivaroxaban/aspirin outcomes cut-off date (06 FEB 2017) was considered. The mean time in follow-up until that date was 702 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Rivaroxaban 2.5mg + Aspirin 100mg | 288 |
| Rivaroxaban 5mg + Aspirin Placebo | 255 |
| Rivaroxaban Placebo + Aspirin 100mg | 170 |
"Modified ISTH major bleeding is defined as: i) Fatal bleeding, or ii) Symptomatic bleeding in a critical area or organ, such as intraarticular, intracranial, intramuscular with compartment syndrome, intraocular, intraspinal, liver, pancreas, pericardial, respiratory, retroperitoneal, adrenal gland or kidney; or bleeding into the surgical site requiring reoperation, or iii) Bleeding leading to hospitalization (major bleeding also includes presentation to an acute care facility with discharge on the same day).~Count of participants from COMPASS LTOLE initiation visit to the first occurrence of the primary safety outcome major bleeding was evaluated. LTOLE: long-term open-lable extension" (NCT01776424)
Timeframe: For each participant, the first occurrence of modified ISTH major bleeding from COMPASS LTOLE initiation visit up until 2 days after the last treatment in LTOLE part was considered. The mean time in follow-up was 421 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| LTOLE Part: Rivaroxaban 2.5mg + Aspirin 100mg | 138 |
(NCT00501059)
Timeframe: Until follow-up (approximately 6 years)
| Intervention | Percentage of participants (Number) | ||
|---|---|---|---|
| all-cause mortality | all cancers excluding non-melanoma skin cancer | colon cancer | |
| Acetylsalicylic Acid (Aspirin, BAYE4465) | 2.55 | 4.02 | 0.48 |
| Placebo | 2.57 | 3.76 | 0.41 |
*all other CV death without fatal MI and fatal stroke. (NCT00501059)
Timeframe: Until follow-up (approximate 6 years)
| Intervention | Percentage of participants (Number) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| MI, stroke, CV death, UA or TIA | MI, stroke or CV death | MI | Non-fatal MI | Stroke | CV death* | UA | TIA | All-cause mortality | |
| Acetylsalicylic Acid (Aspirin, BAYE4465) Per-protocol | 3.40 | 2.72 | 0.98 | 0.84 | 1.06 | 0.69 | 0.21 | 0.50 | 2.85 |
| Placebo Per-protocol | 4.19 | 3.45 | 1.84 | 1.53 | 0.95 | 0.66 | 0.28 | 0.49 | 2.58 |
(NCT00501059)
Timeframe: Until follow-up (approximate 6 years)
| Intervention | Percentage of participants (Number) | ||
|---|---|---|---|
| MI, stroke, CV death, UA or TIA | MI, stroke or CV death | non-fatal MI | |
| Acetylsalicylic Acid (Aspirin, BAYE4465) | 4.29 | 3.32 | 1.40 |
| Placebo | 4.48 | 3.47 | 1.56 |
The percentages of subjects with the efficacy endpoints of confirmed MI, stroke, cardiovascular death, UA and TIA are reported separately. *all other CV death without fatal MI and fatal stroke (NCT00501059)
Timeframe: Until follow-up (approximately 6 years)
| Intervention | Percentage of participants (Number) | ||||
|---|---|---|---|---|---|
| MI | stroke | CV death* | UA | TIA | |
| Acetylsalicylic Acid (Aspirin, BAYE4465) | 1.52 | 1.20 | 0.61 | 0.32 | 0.67 |
| Placebo | 1.78 | 1.07 | 0.62 | 0.32 | 0.72 |
(NCT00501059)
Timeframe: Until follow-up (approximate 6 years)
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Total | Mild | Moderate | Severe | |
| Acetylsalicylic Acid (Aspirin, BAYE4465) | 61 | 42 | 15 | 4 |
| Placebo | 29 | 22 | 5 | 2 |
The time to event was defined as the number of days from the date of randomization to the date of the event confirmed by adjudication. The numbers of days for milestones when 1%, 2%, 3% and 4% of the subjects have reached endpoint events were estimated from Kaplan-Meier-Analyses. (NCT00501059)
Timeframe: Until follow-up (approximately 6 years)
| Intervention | Days (Count of Units) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Days until 1% subjects had all-cause mortality | Days until 2% subjects had all-cause mortality | Days until 3% subjects had all-cause mortality | Days until 4% subjects had all-cause mortality | Days until 1% subjects had all cancer excl. NMSC | Days until 2% subjects had all cancer excl. NMSC | Days until 3% subjects had all cancer excl. NMSC | Days until 4% subjects had all cancer excl. NMSC | Days until 1% subjects had colon cancer | Days until 2% subjects had colon cancer | Days until 3% subjects had colon cancer | Days until 4% subjects had colon cancer | |
| Acetylsalicylic Acid (Aspirin, BAYE4465) | 838 | 1493 | 1970 | NA | 374 | 849 | 1164 | 1542 | NA | NA | NA | NA |
| Placebo | 938 | 1460 | 1963 | NA | 420 | 805 | 1276 | 1751 | NA | NA | NA | NA |
The time to Composite outcome consisting of the first occurrence of cardiovascular death, MI, or stroke (ischemic, hemorrhagic, or unknown) was defined as the number of days from the date of randomization to the date of the event confirmed by adjudication. The numbers of days for milestones when 1%, 2%, 3% and 4% of the subjects have reached endpoint events were estimated from Kaplan-Meier-Analyses. (NCT00501059)
Timeframe: Until follow-up (approximate 6 years)
| Intervention | Days (Count of Units) | |||
|---|---|---|---|---|
| Days until 1% subjects had an efficacy event | Days until 2% subjects had an efficacy event | Days until 3% subjects had an efficacy event | Days until 4% subjects had an efficacy event | |
| Acetylsalicylic Acid (Aspirin, BAYE4465) | 678 | 1167 | 1599 | 1949 |
| Placebo | 522 | 1053 | 1501 | 1930 |
The primary efficacy endpoint was a composite outcome consisting of the first occurrence of confirmed MI, stroke, cardiovascular death, UA, TIA. The time to event was defined as the number of days from the date of randomization to the date of the event confirmed by adjudication. The numbers of days for milestones when 1%, 2%, 3% and 4% of the subjects have reached endpoint events were estimated from Kaplan-Meier-Analyses. (NCT00501059)
Timeframe: Until follow-up (approximate 6 years)
| Intervention | Days (Count of Units) | |||
|---|---|---|---|---|
| Days until 1% subjects had an efficacy event | Days until 2% subjects had an efficacy event | Days until 3% subjects had an efficacy event | Days until 4% subjects had an efficacy event | |
| Acetylsalicylic Acid (Aspirin, BAYE4465) | 528 | 889 | 1225 | 1630 |
| Placebo | 381 | 796 | 1134 | 1582 |
The time to event was defined as the number of days from the date of randomization to the date of the event confirmed by adjudication. The numbers of days for milestones when 1%, 2%, 3% and 4% of the subjects have reached endpoint events were estimated from Kaplan-Meier-Analyses. (NCT00501059)
Timeframe: Until follow-up (approximately 6 years)
| Intervention | Days (Count of Units) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Days until 1% subjects had non-fatal MI | Days until 2% subjects had non-fatal MI | Days until 1% subjects had total MI | Days until 2% subjects had total MI | Days until 1% subjects had non-fatal stroke | Days until 2% subjects had non-fatal stroke | Days until 1% subjects had total stroke | Days until 2% subjects had total stroke | Days until 1% subjects had cardiovascular death | Days until 2% subjects had cardiovascular death | Days until 1% subjects had UA | Days until 2% subjects had UA | Days until 1% subjects had TIA | Days until 2% subjects had TIA | |
| Acetylsalicylic Acid (Aspirin, BAYE4465) | 1309 | NA | 1216 | 2128 | 1576 | NA | 1543 | NA | NA | NA | NA | NA | NA | NA |
| Placebo | 1085 | 2121 | 1014 | 1906 | 1650 | NA | 1627 | NA | NA | NA | NA | NA | NA | NA |
Secondary efficacy outcome: Number of participants with ischemic stroke, myocardial infarction, death from ischemic vascular causes, or major hemorrhage (NCT00991029)
Timeframe: Up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 141 |
| Placebo | 167 |
Primary efficacy outcome: Number of Participants with Ischemic Stroke, Myocardial Infarction, or Death From Ischemic Vascular Causes (NCT00991029)
Timeframe: Up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 121 |
| Placebo | 160 |
Other safety outcome: Number of Participants with Death from any cause (NCT00991029)
Timeframe: up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 18 |
| Placebo | 12 |
Secondary efficacy outcome: Number of participants with Death from ischemic vascular causes (NCT00991029)
Timeframe: Up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 6 |
| Placebo | 4 |
Other safety outcome: Number of participants with Hemorrhagic stroke (NCT00991029)
Timeframe: up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 5 |
| Placebo | 3 |
Secondary efficacy outcome: Number of participants with Ischemic or hemorrhagic stroke (NCT00991029)
Timeframe: Up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 116 |
| Placebo | 156 |
Secondary efficacy outcome:Number of participants with Ischemic stroke (NCT00991029)
Timeframe: Up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 112 |
| Placebo | 155 |
Primary safety outcome: Number of Participants with major hemorrhage (NCT00991029)
Timeframe: Up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 23 |
| Placebo | 10 |
Other safety outcome: Number of Participants with Major hemorrhage other than intracranial hemorrhage (NCT00991029)
Timeframe: up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 17 |
| Placebo | 7 |
Other safety outcome:Number of Participants with Minor hemorrhage (NCT00991029)
Timeframe: up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 40 |
| Placebo | 13 |
Secondary efficacy outcome: Number of participants with Myocardial infarction (NCT00991029)
Timeframe: Up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 10 |
| Placebo | 7 |
Other safety outcome: Number of participants with other symptomatic intracranial hemorrhage (NCT00991029)
Timeframe: up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 2 |
| Placebo | 0 |
Other safety outcome: Number of participants with Symptomatic intracerebral hemorrhage (NCT00991029)
Timeframe: up to 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Clopidogrel | 2 |
| Placebo | 2 |
(NCT00000479)
Timeframe: Average follow-up 10.1 years
| Intervention | participants (Number) | |
|---|---|---|
| Total invasive cancer | Cancer death | |
| Aspirin + Vitamin E | 716 | 152 |
| Aspirin Only | 722 | 132 |
| Both Placebos | 706 | 143 |
| Vitamin E Only | 721 | 156 |
(NCT00000479)
Timeframe: Average follow-up 10.1 years
| Intervention | Participants (Number) | |||
|---|---|---|---|---|
| Major cardiovascular event | Stroke | Myocardial infarction | Cardiovascular death | |
| Aspirin + Vitamin E | 232 | 108 | 102 | 54 |
| Aspirin Only | 245 | 113 | 96 | 66 |
| Both Placebos | 272 | 133 | 99 | 74 |
| Vitamin E Only | 250 | 133 | 94 | 52 |
Follow up appointment within 2 weeks of discharge back to their primary care providers at a primary care facility from a tertiary referral center. (NCT01431846)
Timeframe: Within 2 weeks of discharge
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| Subjects Interviewed | Follow-up within 2 weeks of discharge | Medication reconciliation | Discharge Instructions | |
| Arm 1 | 8 | 3 | 4 | 8 |
| Arm 2 | 3 | NA | NA | NA |
| Arm 3 | 8 | 6 | 8 | 8 |
Clostridium difficile confirmed by polymerase chain reaction (PCR) (NCT02235311)
Timeframe: 8 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Pantoprazole Twice Daily | 0 |
| Pantoprazole Once Daily | 0 |
As defined by clinical suspicion and/or positive sputum culture requiring antibiotic treatment (NCT02235311)
Timeframe: 8 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Pantoprazole Twice Daily | 0 |
| Pantoprazole Once Daily | 0 |
"Per patient report or as defined by follow-up endoscopy per gastroenterology service, 8 weeks after UGIB acute management~High clinical suspicion of rebleed includes melena, hematochezia, confirmed by repeat endoscopy, requiring additional management" (NCT02235311)
Timeframe: 8 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Pantoprazole Twice Daily | 0 |
| Pantoprazole Once Daily | 0 |
as defined by follow-up endoscopy per gastroenterology service, 8 weeks after UGIB acute management (NCT02235311)
Timeframe: 8 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Pantoprazole Twice Daily | 1 |
| Pantoprazole Once Daily | 0 |
Follow-up endoscopy was performed at the end of the 6th month (NCT02418312)
Timeframe: 6 months
| Intervention | participants (Number) |
|---|---|
| Histamine-2 Receptor Antagonist Group | 106 |
| Placebo Group | 101 |
Follow-up endoscopy was performed at the end of the 6th month (NCT02551744)
Timeframe: six month
| Intervention | participants (Number) |
|---|---|
| Proton Pump Inhibitor Group | 1 |
| Histamine-2 Receptor Antagonist Group | 7 |
Anesthesia start time determined from anesthesia portion of the medical record. Time at which discharge order was placed will serve as time of discharge. (NCT01592708)
Timeframe: Anesthesia start time to placement of hospital discharge order - average 26 - 28 hours
| Intervention | hours (Median) |
|---|---|
| Intervention Cohort | 26.4 |
| Comparison Cohort | 28.2 |
To be assessed based on patient diary completed daily for 1 week following discharge to home from the hospital (NCT01592708)
Timeframe: 1 week from discharge from hospital
| Intervention | percentage of subjects with PDN (Number) |
|---|---|
| Intervention Cohort | 72 |
| Comparison Cohort | 60 |
(NCT01592708)
Timeframe: 1 week post discharge
| Intervention | percentage of subjects with PDV (Number) |
|---|---|
| Intervention Cohort | 22 |
| Comparison Cohort | 29 |
End of surgery time determined by anesthesia portion of the medical record. PONV to be assessed by review of surgeons' and nurses' notes in the medical record as well as through review of patient diaries. Vomiting constitutes a safety issue and, as such, associated adverse events will be noted. (NCT01592708)
Timeframe: End of surgery to discharge from hospital
| Intervention | percentage of subjects with PON (Number) |
|---|---|
| Intervention Cohort | 24 |
| Comparison Cohort | 70 |
(NCT01592708)
Timeframe: End of surgery to discharge from hospital
| Intervention | percentage of subjects with POV (Number) |
|---|---|
| Intervention Cohort | 11 |
| Comparison Cohort | 28 |
- Early preterm delivery (<34 weeks) (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 189 |
| Placebo Arm | 230 |
- Birth weight <2500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1078 |
| Placebo Arm | 1153 |
- Birth weight <1500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 78 |
| Placebo Arm | 101 |
- Incidence of Fetal Loss (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 303 |
| Placebo Arm | 353 |
- Incidence of Spontaneous Abortion (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 134 |
| Placebo Arm | 152 |
- Incidence of All stillbirth (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 141 |
| Placebo Arm | 166 |
- Incidence of Medical Termination of Pregnancy (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 42 |
| Placebo Arm | 30 |
- Hypertensive disorders of pregnancy is defined by the characterization of evidence of a hypertensive disorder, including either preeclampsia or eclampsia occurring during the pregnancy. (NCT02409680)
Timeframe: Evidence of hypertensive disorder during the pregnancy (prior to delivery/birth)
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 352 |
| Placebo Arm | 325 |
- Incidence of Perinatal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 264 |
| Placebo Arm | 309 |
The primary outcome of this study is incidence of preterm birth, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks. This will be determined based on actual date of delivery in comparison to the projected estimated due date (EDD), independent of whether or not the preterm delivery is indicated or spontaneous. (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 668 |
| Placebo Arm | 754 |
- Small for gestational age (SGA) as defined by the INTERGROWTH-21st standard (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1506 |
| Placebo Arm | 1564 |
- Vaginal bleeding (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 214 |
| Placebo Arm | 246 |
- Antepartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 26 |
| Placebo Arm | 25 |
- Postpartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 54 |
| Placebo Arm | 43 |
- Incidence of Maternal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 9 |
| Placebo Arm | 12 |
- Incidence of Late Abortion (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 23 |
| Placebo Arm | 30 |
Hemoglobin < 7.0 gm/dl at 26-30 weeks gestation or a drop of 3.5+ gm/dl from screening to 26-30 weeks gestation (NCT02409680)
Timeframe: At enrollment, 4 weeks post enrollment, and 26-30 weeks GA.
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 290 |
| Placebo Arm | 333 |
Early preterm delivery (<34 weeks) and hypertensive disorders (i.e.: preeclampsia) (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 8 |
| Placebo Arm | 21 |
Postoperative hemorrhage is defined as any history of bleeding occurring within the 14 day postoperative period. Hemorrhage will be stratified into 3 levels of severity. Level 1: includes children with a history of postoperative bleeding evaluated and/or treated by a physician in the emergency room, inpatient unit or operating room; Level 2: children requiring inpatient admission for postoperative bleeding regardless of the need for operative intervention; Level 3: children requiring inpatient admission and return to the operating room for control of post-tonsillectomy hemorrhage. (NCT01605903)
Timeframe: Data about post-tonsillectomy bleeding will be obtained after the end of a 14-day postoperative period.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment With Ibuprofen | 10 |
| Treatment With Acetaminophen | 4 |
203 reviews available for aspirin and Gastrointestinal Hemorrhage
| Article | Year |
|---|---|
Benefits and Risks Associated with Low-Dose Aspirin Use for the Primary Prevention of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Randomized Control Trials and Trial Sequential Analysis.
Topics: Aged; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Gastrointestinal Hemorrhage; Humans; Intr | 2022 |
Association of Antisecretory Drugs with Upper Gastrointestinal Bleeding in Patients Using Oral Anticoagulants: A Systematic Review and Meta-Analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Gastrointestinal Agents; Gastroint | 2022 |
Regular Aspirin Use Is Associated with a Reduced Risk of Hepatocellular Carcinoma (HCC) in Chronic Liver Disease: a Systematic Review and Meta-analysis.
Topics: Aspirin; Carcinoma, Hepatocellular; Gastrointestinal Hemorrhage; Hepatitis, Viral, Human; Humans; In | 2023 |
The risk of aspirin induced postoperative hemorrhage: a systematic review and meta-analysis.
Topics: Aspirin; Endoscopic Mucosal Resection; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Platelet | 2022 |
The relationship between aspirin consumption and hepatocellular carcinoma: a systematic review and meta-analysis.
Topics: Aspirin; Carcinoma, Hepatocellular; Gastrointestinal Hemorrhage; Humans; Liver Neoplasms; Prospectiv | 2023 |
Impact of proton pump inhibitors on the risk of small bowel or colorectal bleeding: A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Gastrointestinal Hemorrhage; | 2023 |
Antiplatelets, anticoagulants, and colonoscopic polypectomy.
Topics: Anticoagulants; Aspirin; Colonic Polyps; Colonoscopy; Deprescriptions; Embolism; Factor Xa Inhibitor | 2020 |
Aspirin vs. P2Y12 Inhibitor Rivalry: Which One Can be Continued During Gastrointestinal Bleeding.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhag | 2019 |
A comparison of contemporary versus older studies of aspirin for primary prevention.
Topics: Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Humans; Intracranial Hemorrhages; Neo | 2020 |
Current knowledge on non-steroidal anti-inflammatory drug-induced small-bowel damage: a comprehensive review.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Capsule Endoscopy; Gas | 2020 |
Effect of low-dose aspirin on health outcomes: An umbrella review of systematic reviews and meta-analyses.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Risk Assessment | 2020 |
Drug interactions with apixaban: A systematic review of the literature and an analysis of VigiBase, the World Health Organization database of spontaneous safety reports.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Area Under Curve; Aspirin; | 2020 |
Triple Antithrombotic Therapy in Patients With Left Ventricular Assist Devices.
Topics: Anticoagulants; Aspirin; Drug Therapy, Combination; Fibrinolytic Agents; Gastrointestinal Hemorrhage | 2022 |
Primary Prevention of CVD with Aspirin: Benefits vs Risks.
Topics: Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Gastrointestinal Hemorrhage; Humans; Met | 2021 |
Safety of transrectal ultrasound-guided prostate biopsy in patients receiving aspirin: An update meta-analysis including 3373 patients.
Topics: Aspirin; Biopsy, Needle; Clinical Trials as Topic; Gastrointestinal Hemorrhage; Hematuria; Hemosperm | 2021 |
Aspirin for Primary Prevention.
Topics: Age Factors; Aspirin; Cardiovascular Diseases; Colorectal Neoplasms; Diabetes Mellitus; Gastrointest | 2017 |
Effects of antithrombotic therapy on bleeding after endoscopic submucosal dissection.
Topics: Anticoagulants; Aspirin; Deprescriptions; Endoscopic Mucosal Resection; Endoscopy, Gastrointestinal; | 2017 |
Usefulness of PA32540 in Protecting the Gastric Layer While Providing Secondary Prevention for Coronary Artery Disease.
Topics: Administration, Oral; Aspirin; Coronary Artery Disease; Double-Blind Method; Drug Combinations; Gast | 2017 |
A Primer on Bleeding Risk and Management Strategies of Newer Oral Anti Platelet Agents in Cardiovascular Disease.
Topics: Adenosine; Administration, Oral; Aspirin; Cardiovascular Diseases; Clopidogrel; Gastrointestinal Hem | 2016 |
PPIs Prevent Aspirin-Induced Gastrointestinal Bleeding Better than H2RAs. A Systematic Review and Meta-analysis.
Topics: Aspirin; Drug Administration Schedule; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans | 2017 |
Clinical Inquiries: What are the benefits and risks of daily low-dose aspirin for primary prevention of CV events?
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Female; Gastrointestinal Hemorrhag | 2018 |
Non-variceal upper gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Duodenum; Endoscopy; Esophagus; Ga | 2018 |
Non-variceal upper gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Duodenum; Endoscopy; Esophagus; Ga | 2018 |
Non-variceal upper gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Duodenum; Endoscopy; Esophagus; Ga | 2018 |
Non-variceal upper gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Duodenum; Endoscopy; Esophagus; Ga | 2018 |
[Proton pump inhibitors when using clopidogrel: balance between necessity and disadvantages].
Topics: Aspirin; Clopidogrel; Drug Interactions; Female; Gastrointestinal Diseases; Gastrointestinal Hemorrh | 2019 |
Aspirin for Primary Prevention of Cardiovascular Events.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrha | 2019 |
Role of aspirin in primary prevention of cardiovascular disease.
Topics: Aspirin; Brain Ischemia; Cardiovascular Diseases; Diabetes Complications; Gastrointestinal Hemorrhag | 2019 |
Role of aspirin in primary prevention of cardiovascular disease.
Topics: Aspirin; Brain Ischemia; Cardiovascular Diseases; Diabetes Complications; Gastrointestinal Hemorrhag | 2019 |
Role of aspirin in primary prevention of cardiovascular disease.
Topics: Aspirin; Brain Ischemia; Cardiovascular Diseases; Diabetes Complications; Gastrointestinal Hemorrhag | 2019 |
Role of aspirin in primary prevention of cardiovascular disease.
Topics: Aspirin; Brain Ischemia; Cardiovascular Diseases; Diabetes Complications; Gastrointestinal Hemorrhag | 2019 |
Pharmacogenomics of acetylsalicylic acid and other nonsteroidal anti-inflammatory agents: clinical implications.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Chemical and Drug I | 2013 |
[Gastrointestinal bleeding in the elderly].
Topics: Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diagnosis, D | 2014 |
Low-dose acetylsalicylic acid use and the risk of upper gastrointestinal bleeding: a meta-analysis of randomized clinical trials and observational studies.
Topics: Aspirin; Cardiovascular Diseases; Duodenal Diseases; Esophageal Diseases; Gastrointestinal Hemorrhag | 2013 |
Clinical features of gastroduodenal injury associated with long-term low-dose aspirin therapy.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; | 2013 |
[Antithrombotic drug and gastrointestinal injuries].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Fibrinolytic Agents; Gastrointestinal Hemorrhage; | 2013 |
Optimizing the use of aspirin for cardiovascular prevention.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Dose-Response Relationshi | 2013 |
Histamine H2 receptor antagonists for decreasing gastrointestinal harms in adults using acetylsalicylic acid: systematic review and meta-analysis.
Topics: Aspirin; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Peptic Ulcer; Platelet Aggre | 2012 |
[Oral antiplatelet agents can still be used along with proton pump inhibitors in spite of drug interactions].
Topics: Adenosine; Administration, Oral; Aspirin; Clopidogrel; Cyclooxygenase Inhibitors; Drug Interactions; | 2013 |
Aspirin for prophylactic use in the primary prevention of cardiovascular disease and cancer: a systematic review and overview of reviews.
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Colorectal Neoplasms; Confidence Intervals; Female; G | 2013 |
Role of aspirin in cancer prevention.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Chemotherapy, Adjuvant; D | 2013 |
Aspirin and non-aspirin NSAIDs increase risk of colonic diverticular bleeding: a systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diverticulum, Colon; Gastrointestinal Hemorrhage; | 2014 |
Aspirin in primary prevention of cardiovascular disease and cancer: a systematic review of the balance of evidence from reviews of randomized trials.
Topics: Aspirin; Cerebral Hemorrhage; Female; Gastrointestinal Hemorrhage; Humans; Male; Neoplasms; Platelet | 2013 |
Aspirin and proton pump inhibitor combination therapy for prevention of cardiovascular disease and Barrett's esophagus.
Topics: Aspirin; Barrett Esophagus; Cardiovascular Diseases; Colorectal Neoplasms; Drug Combinations; Gastro | 2014 |
[Enteric-coated aspirin does not reduce the risk of gastrointestinal side effects].
Topics: Aspirin; Dyspepsia; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Risk Factors; Tablets, Ente | 2014 |
Estimates of benefits and harms of prophylactic use of aspirin in the general population.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; | 2015 |
[Therapy for prevention of upper gastrointestinal bleeding in patients receiving anti-thrombotic therapy].
Topics: Anticoagulants; Aspirin; Clinical Trials as Topic; Gastrointestinal Hemorrhage; Humans; Platelet Agg | 2014 |
Gastrointestinal bleeding in cardiac patients: epidemiology and evolving clinical paradigms.
Topics: Age Factors; Anticoagulants; Aspirin; Gastrointestinal Hemorrhage; Heart Diseases; Hemostasis, Endos | 2014 |
Prophylactic use of aspirin: systematic review of harms and approaches to mitigation in the general population.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointestinal Diseases; Gastroin | 2015 |
Epidemiology and diagnosis of acute nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Diseases; Endoscopy, Gastr | 2014 |
Small bowel injury in low-dose aspirin users.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capsule Endoscopy; Drug Administration Schedule; G | 2015 |
Effect of esomeprazole on gastroduodenal erosions in patients at increased gastrointestinal risk treated with low-dose acetylsalicylic acid: a post-hoc analysis of the OBERON trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Esomeprazole; Ga | 2015 |
New insight into the mechanisms of gastroduodenal injury induced by nonsteroidal anti-inflammatory drugs: practical implications.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Duodenal Ulcer; Gastric | 2015 |
Should patients prescribed long-term low-dose aspirin receive proton pump inhibitors? A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Dose-Response Relationshi | 2015 |
Should patients stop taking aspirin for primary prevention?
Topics: Aspirin; Cardiovascular Diseases; Decision Making; Gastrointestinal Hemorrhage; Humans; Platelet Agg | 2015 |
Systematic review with meta-analysis: the risk of gastrointestinal haemorrhage post-polypectomy in patients receiving anti-platelet, anti-coagulant and/or thienopyridine medications.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Coagulation Disorders; Colon | 2015 |
Dual antiplatelet therapy with clopidogrel and aspirin for secondary stroke prevention.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Evidence-Based Medicine; Gastrointestinal Hemorrhag | 2015 |
A Balanced View of Efficacy and Safety of Aspirin in Cardiovascular Diseases.
Topics: Animals; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation | 2015 |
Prevention of Upper Gastrointestinal Ulcer and Complications in Low-Dose Aspirin Users.
Topics: Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Platel | 2015 |
Low-Dose Aspirin-Associated Upper and Mid Gastrointestinal Tract Damage and Gene Polymorphism.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Gastrointestinal Tr | 2015 |
[Gastrointestinal bleeding].
Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; Celecox | 2015 |
Prediction models for intracranial hemorrhage or major bleeding in patients on antiplatelet therapy: a systematic review and external validation study.
Topics: Algorithms; Anticoagulants; Aspirin; Brain Ischemia; Calibration; Cerebral Hemorrhage; Dipyridamole; | 2016 |
Where Do We Stand With Aspirin for the Prevention of Colorectal Cancer? The USPSTF Recommendations.
Topics: Aged; Aspirin; Chemoprevention; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Adminis | 2016 |
Bleeding Risks With Aspirin Use for Primary Prevention in Adults: A Systematic Review for the U.S. Preventive Services Task Force.
Topics: Adult; Aspirin; Cardiovascular Diseases; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Hemorrhag | 2016 |
Drug-disease interactions: narrative review of aspirin in gastric ulcer.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Research Design; Stom | 2016 |
Aspirin for Primary Prevention of Atherosclerotic Cardiovascular Disease: Advances in Diagnosis and Treatment.
Topics: Aspirin; Cardiovascular Diseases; Chemoprevention; Colorectal Neoplasms; Evidence-Based Medicine; Fe | 2016 |
Bleeding Risk with Long-Term Low-Dose Aspirin: A Systematic Review of Observational Studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Databases, F | 2016 |
The role of aspirin in preventing colorectal cancer.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Gastrointestinal Hemorrhage; | 2016 |
Proton Pump Inhibitors in Cardiovascular Disease: Drug Interactions with Antiplatelet Drugs.
Topics: Adenosine; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Administration Schedule; Drug Dosage | 2017 |
Systematic Review and Meta-Analysis of Randomised Trials to Ascertain Fatal Gastrointestinal Bleeding Events Attributable to Preventive Low-Dose Aspirin: No Evidence of Increased Risk.
Topics: Aspirin; Drug-Related Side Effects and Adverse Reactions; Gastrointestinal Hemorrhage; Humans; Myoca | 2016 |
Efficacy of aspirin (325 mg) + omeprazole (40 mg) in treating coronary artery disease.
Topics: Aspirin; Cardiovascular Diseases; Coronary Artery Disease; Gastrointestinal Diseases; Gastrointestin | 2017 |
East Asian perspective on the interaction between proton pump inhibitors and clopidogrel.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anticoagulants; Asia, Eastern; Asian People; Aspirin; Clopi | 2017 |
Cyclooxygenase-2 inhibitors in colorectal cancer prevention: counterpoint.
Topics: Animals; Aspirin; Cardiovascular Diseases; Chemoprevention; Clinical Trials as Topic; Colorectal Neo | 2008 |
[Risk of gastrointestinal bleeding with aspirin and platelet antiaggregants].
Topics: Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal | 2009 |
[Anticoagulation and antiplatelet therapy, and gastrointestinal endoscopy].
Topics: Algorithms; Ampulla of Vater; Anticoagulants; Aspirin; Decision Trees; Drug Administration Schedule; | 2009 |
Aspirin for the primary prevention of cardiovascular events: an update of the evidence for the U.S. Preventive Services Task Force.
Topics: Age Factors; Aged; Aspirin; Cardiovascular Diseases; Female; Gastrointestinal Hemorrhage; Humans; Ma | 2009 |
Predicting poor outcome from acute upper gastrointestinal hemorrhage.
Topics: Aging; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Endoscopy, Gastrointestinal; Esophageal and | 2009 |
Management of patients with high gastrointestinal risk on antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Peptic Ulcer Hemorrhage; Pi | 2009 |
Aggressive chronic platelet inhibition with prasugrel and increased cancer risks: revising oral antiplatelet regimens?
Topics: Animals; Aspirin; Clopidogrel; Colonic Neoplasms; Gastrointestinal Hemorrhage; Humans; Piperazines; | 2009 |
Aspirin for primary prevention: do potential benefits outweigh the risks?
Topics: Animals; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Humans; Neoplasms; Primary P | 2009 |
[Prevention of GI bleeding due to antiplatelet agents: a labyrinth!].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Comb | 2009 |
Gastrointestinal bleed with clopidogrel and aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; | 2010 |
Current standings of the proton pump inhibitor and clopidogrel co-therapy: review on an evolving field with the eyes of the gastroenterologist.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug Interactions; Dr | 2010 |
Antiplatelet and antithrombotic treatment of patients with peripheral arterial disease.
Topics: Administration, Oral; Aspirin; Cardiovascular Diseases; Clopidogrel; Disease Progression; Dose-Respo | 2010 |
Clinical inquiries. Is aspirin effective for primary prevention of colon cancer?
Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Neoplasms; Colorectal Neoplasms; | 2010 |
Gastrointestinal bleeding associated with low-dose aspirin use: relevance and management in clinical practice.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal | 2011 |
[Antiplatelet therapy in coronary heart disease. Some problems and achivements].
Topics: Acute Coronary Syndrome; Adenosine; Angioplasty, Balloon, Coronary; Aryl Hydrocarbon Hydroxylases; A | 2010 |
Systematic review: Helicobacter pylori and the risk of upper gastrointestinal bleeding risk in patients taking aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Helicobacter Infectio | 2010 |
Aspirin for primary prevention of cardiovascular disease in diabetes mellitus.
Topics: Aged; Aspirin; Cardiovascular Diseases; Diabetes Complications; Drug Resistance; Female; Gastrointes | 2010 |
ACCF/ACG/AHA 2010 Expert Consensus Document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Dise | 2010 |
ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Cardiovascular Dise | 2010 |
Cilostazol versus aspirin for secondary prevention of vascular events after stroke of arterial origin.
Topics: Asian People; Aspirin; Brain Ischemia; Cause of Death; Cilostazol; Gastrointestinal Hemorrhage; Huma | 2011 |
Gastrointestinal bleeding after percutaneous coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Intestine | 2011 |
[Coronary heart disease - what is of importance after coronary intervention?].
Topics: Adenosine; Aftercare; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Coronary | 2011 |
Asia-Pacific Working Group consensus on non-variceal upper gastrointestinal bleeding.
Topics: Aspirin; Drug Therapy, Combination; Embolization, Therapeutic; Endoscopy, Gastrointestinal; Evidence | 2011 |
Proton pump inhibitors in rheumatic diseases: clinical practice, drug interactions, bone fractures and risk of infections.
Topics: Anticoagulants; Aryl Hydrocarbon Hydroxylases; Aspirin; Calcium, Dietary; Clopidogrel; Clostridioide | 2011 |
Effect of aspirin on mortality in the primary prevention of cardiovascular disease.
Topics: Adult; Aged; Aspirin; Cardiovascular Agents; Cause of Death; Female; Gastrointestinal Hemorrhage; Hu | 2011 |
Gastrointestinal effects of aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Gastric Mucosa; Gastroint | 2011 |
Low doses of acetylsalicylic acid increase risk of gastrointestinal bleeding in a meta-analysis.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Incidence; Randomized Controlled Trials as Topic; Risk | 2011 |
[Results of the Cilostazol Stroke Prevention Study II (CSPS II): a randomized controlled trial for the comparison of cilostazol and aspirin in stroke patients].
Topics: Aspirin; Cilostazol; Gastrointestinal Hemorrhage; Humans; Japan; Platelet Aggregation Inhibitors; Ra | 2010 |
Clopidogrel and PPI interaction: clinically relevant or not?
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; | 2012 |
[Pathophysiology and treatment of drug-induced injury in gastrointestinal tract].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastrointestinal Diseases; Gastroi | 2011 |
Optimal drug therapy after aspirin-induced upper gastrointestinal bleeding.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Pl | 2012 |
Gastrointestinal lesions and complications of low-dose aspirin in the gastrointestinal tract.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Diseases; Gastrointestinal Hemorr | 2012 |
Risk factors for gastrointestinal bleeding associated with low-dose aspirin.
Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Cardiovascular Diseas | 2012 |
Prevention of damage induced by aspirin in the GI tract.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Drug S | 2012 |
Balancing the risk and benefits of low-dose aspirin in clinical practice.
Topics: Aspirin; Cardiovascular Diseases; Colorectal Neoplasms; Gastrointestinal Hemorrhage; Hemorrhage; Hum | 2012 |
Aspirin and NSAIDs; benefits and harms for the gut.
Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Barrett Esophagus; Cardiovascular Disease | 2012 |
Clopidogrel and proton pump inhibitors--where do we stand in 2012?
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Aspirin; Biotransformation; Cardiovascular Diseases; Clopido | 2012 |
Antiplatelet therapy and proton pump inhibition: cause for concern?
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Blood Platelets; Cytochrome P-450 CYP2C19; Gastrointestinal | 2012 |
Drug interactions in the treatment of depression in patients with ischemic heart disease.
Topics: Aged; Antidepressive Agents; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Comorbidity; Cytoc | 2012 |
Reinitiating aspirin therapy for primary prevention of cardiovascular events in a patient post-aspirin-induced upper gastrointestinal bleed: a case report and review of literature.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Car | 2013 |
Evaluation of the benefits and risks of low-dose aspirin in the secondary prevention of cardiovascular and cerebrovascular events.
Topics: Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Gastrointestinal Hemorrhage; Humans; My | 2002 |
The public health potential of aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Colonic Neoplasms; Female | 2002 |
Gastrointestinal safety of low-dose aspirin.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Consumer Product Sa | 2002 |
[Gastrointestinal complications of nonsteroidal anti-inflammatory drugs and low-dose aspirin].
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Cyclooxygenase Inhi | 2003 |
Assessment of non-steroidal anti-inflammatory drug (NSAID) damage in the human gastrointestinal tract.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyc | 2003 |
Treatment and prevention of aspirin-induced gastroduodenal ulcers and gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Dru | 2002 |
[Secondary and primary prophylaxis of gastropathy associated with nonsteroidal antiinflammatory drugs or low-dose-aspirin: a review based on four clinical scenarios].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Gastrointestinal | 2003 |
A critical review of selective serotonin reuptake inhibitor-associated bleeding: balancing the risk of treating hepatitis C-infected patients.
Topics: Analgesics; Antidepressive Agents; Antiviral Agents; Aspirin; Depressive Disorder; Drug Interactions | 2003 |
[Risk factors for gastrointestinal bleeding associated with low-dose aspirin].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Clinical Trials as Topic; Co | 2003 |
[Digestive and hemorrhage complications of low-dose aspirin].
Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Co | 2003 |
[Role of Helicobacter pylori in drug-induced gastrointestinal bleeding].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relations | 2003 |
[Impact of Helicobacter pylori infection on the risk of gastro-duodenal ulcer in patients treated with nonsteroidal antiinflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Helicobacter Infectio | 2004 |
Application of U.S. guidelines in other countries: aspirin for the primary prevention of cardiovascular events in Japan.
Topics: Adult; Age Distribution; Aged; Aspirin; Cardiovascular Diseases; Evidence-Based Medicine; Female; Ga | 2004 |
Cardioprotective effects and gastrointestinal risks of aspirin: maintaining the delicate balance.
Topics: Aged; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug Ad | 2004 |
[Digestive bleeding and anti-inflammatory drugs at the teaching hospital of Brazzaville].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Comorbidity; Congo; Femal | 2004 |
Aspirin for everyone older than 50? Against.
Topics: Aged; Aspirin; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Middle Aged; Myocardial Inf | 2005 |
Gastrointestinal injury from NSAID therapy. How to reduce the risk of complications.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Dyspepsia; Gastrointest | 2005 |
Aspirin for the primary prevention of cardiovascular disease: a comprehensive review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cerebral Hemorrhage; Dose | 2005 |
[Primary prevention of coronary heart disease with aspirin].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Comorbidity; Coronary Di | 2005 |
Upper gastrointestinal haemorrhage complicating antiplatelet treatment with aspirin and/or clopidogrel: where we are now?
Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, | 2006 |
Low-dose aspirin for the prevention of atherothrombosis.
Topics: Arteriosclerosis; Aspirin; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Interactions; Drug Resi | 2005 |
Low-dose aspirin for the prevention of atherothrombosis.
Topics: Arteriosclerosis; Aspirin; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Interactions; Drug Resi | 2005 |
Low-dose aspirin for the prevention of atherothrombosis.
Topics: Arteriosclerosis; Aspirin; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Interactions; Drug Resi | 2005 |
Low-dose aspirin for the prevention of atherothrombosis.
Topics: Arteriosclerosis; Aspirin; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Interactions; Drug Resi | 2005 |
Nitric oxide, aspirin-triggered lipoxins and NO-aspirin in gastric protection.
Topics: Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Gastric Mu | 2006 |
Gastrointestinal Considerations in Patients with Cardiovascular Disease Using Nonopioid Analgesics for Mild-to-Moderate Pain or Cardioprotection.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2 Inhibito | 2006 |
Incidence and management of bevacizumab-related toxicities in colorectal cancer.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticoa | 2006 |
NSAID-induced gastrointestinal damage: current clinical management and recommendations for prevention.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2 Inhibitors; Drug Combinations; Dy | 2006 |
Unmet needs in non-steroidal anti-inflammatory drug-induced upper gastrointestinal diseases.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2 Inhibito | 2006 |
Review article: gastrointestinal bleeding with low-dose aspirin - what's the risk?
Topics: Adrenal Cortex Hormones; Aging; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Ca | 2006 |
Does a coxib-associated thrombotic risk limit the clinical use of the compounds as analgesic, antiinflammatory drugs? Arguments against.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Cardiovascular Diseases; Cl | 2006 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Cyclooxyge | 2007 |
Iron deficiency in childhood and adolescence: retrospective review.
Topics: Adolescent; Anemia, Iron-Deficiency; Animals; Aspirin; Cattle; Celiac Disease; Child; Child, Prescho | 2006 |
Antiplatelet therapy and the risk of bleeding induced by gastrointestinal endoscopic procedures. A systematic review of the literature and recommendations.
Topics: Aspirin; Biopsy, Needle; Bleeding Time; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Hu | 2007 |
Building a better aspirin: gaseous solutions to a century-old problem.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemistry, Pharmaceutical; Gastrointestinal Hemorr | 2007 |
Does enteric-coated aspirin result in a lower incidence of gastrointestinal complications compared to normal aspirin?
Topics: Aspirin; Coronary Artery Bypass; Evidence-Based Medicine; Gastrointestinal Hemorrhage; Humans; Posto | 2007 |
Does clopidogrel rather than aspirin plus a proton-pump inhibitor reduce the frequency of gastrointestinal complications after cardiac surgery?
Topics: Aspirin; Cardiac Surgical Procedures; Clopidogrel; Drug Therapy, Combination; Evidence-Based Medicin | 2007 |
Upper GI risks of NSAIDs and antiplatelet agents: key issues for the cardiologist.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cardiology; Cardiovascular Dise | 2005 |
Strategies to reduce the GI risks of antiplatelet therapy.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cardiova | 2005 |
Aspirin and gastrointestinal toxicity.
Topics: Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Helicobacter pylor | 2007 |
[Untoward side effects of acetylsalicylic acid].
Topics: Adolescent; Adult; Angioedema; Aspirin; Asthma; Child; Child, Preschool; Female; Fetus; Gastrointest | 1984 |
Use of antipyretic analgesics in the pediatric patient.
Topics: Acetaminophen; Adolescent; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemic | 1983 |
Gastrointestinal effects of antipyretic analgesics.
Topics: Acetaminophen; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bicarbonate | 1983 |
Gastroduodenal damage due to drugs, alcohol and smoking.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Ethanol; Gastric Mucosa; Gastrointestinal | 1984 |
Cardiogenic cerebral embolism.
Topics: Anticoagulants; Aspirin; Cardiac Surgical Procedures; Cerebral Hemorrhage; Cerebral Infarction; Dipy | 1984 |
Identification & management of defects in platelet hemostasis in massively transfused patients.
Topics: Animals; Aspirin; Bleeding Time; Blood Preservation; Blood Transfusion; Cardiopulmonary Bypass; Cell | 1982 |
[The most common drugs considered harmful to the stomach, Clinical and endoscopic studies].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Dyspepsia; Fema | 1980 |
Drug-induced peptic ulcer and upper gastrointestinal bleeding.
Topics: Adrenal Cortex Hormones; Alcoholism; Animals; Aspirin; Diuretics; Emepronium; Female; Gastrointestin | 1980 |
Gastrointestinal toxicity of minor analgesics.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Caffeine; Drug Combinations; Gastroi | 1980 |
[Gastric lesions induced by anti-inflammatory drugs (author's transl)].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aspirin; Gastrointestinal Hemorrhage; Humans; Pep | 1981 |
Gastrointestinal bleeding during low-dose aspirin administration for prevention of arterial occlusive events. A critical analysis.
Topics: Aged; Arterial Occlusive Diseases; Aspirin; Clinical Trials as Topic; Drug Administration Schedule; | 1995 |
Effects of nonsteroidal antiinflammatory drugs on platelet function and systemic hemostasis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Platelets; Cyclooxygenase Inh | 1995 |
Efficacy and safety of different aspirin dosages on vascular diseases in high-risk patients. A metaregression analysis.
Topics: Aspirin; Cerebral Hemorrhage; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Gastroint | 1995 |
Massive bleeding from a Zenker's diverticulum: case report and review of the literature.
Topics: Aged; Aspirin; Gastrointestinal Hemorrhage; Humans; Male; Zenker Diverticulum | 1994 |
Review article: aspirin and gastrointestinal bleeding.
Topics: Anemia, Hypochromic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gast | 1994 |
The gastrointestinal toxicity of aspirin: an overview of randomised controlled trials.
Topics: Aged; Aspirin; Cardiovascular Diseases; Digestive System; Female; Gastrointestinal Diseases; Gastroi | 1993 |
[Aspirin dosage for prevention of cerebral infarct: arguments for low dosage].
Topics: Aspirin; Cerebral Infarction; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administra | 1995 |
[Acetylsalicylic acid and gastrointestinal hemorrhages: preferably a lower dosage].
Topics: Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; H | 1996 |
Aspirin: benefit and risk in thromboprophylaxis.
Topics: Aspirin; Blood Loss, Surgical; Case-Control Studies; Gastrointestinal Hemorrhage; Humans; Platelet A | 1998 |
[Innocuous NSAID: myth or reality?].
Topics: Adult; Age Factors; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Vessels; | 1998 |
Non-steroidal anti-inflammatory drugs and gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Female; Gastroin | 1999 |
Ticlopidine-induced aplastic anemia and quick recovery with G-CSF: case report and literature review.
Topics: Aged; Aged, 80 and over; Anemia, Aplastic; Aspirin; Bone Marrow Cells; Coronary Disease; Female; Gas | 2000 |
[Digestive complications of aspirin].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Digestive System; | 2000 |
Risk of gastrointestinal haemorrhage with long term use of aspirin: meta-analysis.
Topics: Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fibrinolytic Agents; Gastroint | 2000 |
Non-steroidal anti-inflammatory drugs and gastrointestinal damage-problems and solutions.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cyclooxygenase Inhibitors | 2001 |
Cyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Blood Platelets; Cardiova | 2001 |
Upper gastrointestinal complications: the causes, consequences, and clinical outcomes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Cyclooxygenase Inhibitor | 2001 |
Aspirin for the primary prevention of cardiovascular events: a summary of the evidence for the U.S. Preventive Services Task Force.
Topics: Adult; Aged; Aspirin; Chemoprevention; Coronary Disease; Evidence-Based Medicine; Female; Fibrinolyt | 2002 |
[Acute gastrointestinal bleeding in patients with antithrombotic therapy].
Topics: Acute Disease; Anticoagulants; Aspirin; Coumarins; Deamino Arginine Vasopressin; Gastrointestinal He | 2002 |
The biochemical pathology of aspirin-induced gastric damage.
Topics: Age Factors; Alcohol Drinking; Animals; Anti-Inflammatory Agents; Ascorbic Acid Deficiency; Aspirin; | 1975 |
Effective use of analgesic drugs.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ast | 1976 |
Harmful effects of "aspirin compounds".
Topics: Acid-Base Equilibrium; Aspirin; Blood Coagulation; Blood Platelets; Carbon Dioxide; Digestive System | 1977 |
Hematologic perturbations associated with salicylate.
Topics: Aspirin; Blood Platelets; Gastrointestinal Hemorrhage; Hematologic Diseases; Hematopoietic System; H | 1979 |
The role of the mucosal barrier in drug-induced gastric ulceration and erosions.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Ethanol; Gastric Juice; Gastric Mucosa; | 1976 |
Aspirin revisited.
Topics: Animals; Aspirin; Blood Platelets; Clinical Trials as Topic; Gastrointestinal Hemorrhage; Hemostasis | 1975 |
Gastric mucosal damage by aspirin.
Topics: Anemia, Hypochromic; Animals; Aspirin; Cats; Dogs; Ferrets; Gastric Juice; Gastric Mucins; Gastric M | 1975 |
Upper gastrointestinal safety with nabumetone.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Chromium Radioisotopes; Clinical Trials | 1992 |
Aspirin and other platelet active drugs. Relationship among dose, effectiveness, and side effects.
Topics: Aspirin; Blood Platelets; Dipyridamole; Epoprostenol; Gastrointestinal Hemorrhage; Humans; Platelet | 1989 |
Incidence of gastropathy in destructive arthropathies.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Esophagus; Female; Gastrointestinal H | 1989 |
Mechanisms of nonsteroidal anti-inflammatory drug-induced gastric damage. Actions of therapeutic agents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Diseases; Gastrointestinal Hemorr | 1988 |
Ulcerogenic drugs and upper gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Glucocorticoids; Huma | 1988 |
Clinical spectrum of the upper gastrointestinal effects of nonsteroidal anti-inflammatory drugs. Natural history, symptomatology, and significance.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Diseases; Gastrointestinal Hemorr | 1988 |
NSAID-induced gastric mucosal damage.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Female; Gastric Mucosa; Ga | 1987 |
Aspirin and the stomach.
Topics: Acute Disease; Adaptation, Physiological; Anemia; Animals; Aspirin; Buffers; Chronic Disease; Dose-R | 1986 |
[Effect of some antirheumatic agents on the gastric mucous membrane].
Topics: Adrenocorticotropic Hormone; Aged; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheuma | 1971 |
Acute gastric mucosal bleeding.
Topics: Acute Disease; Aspirin; Blood Transfusion; Cell Membrane Permeability; Gastric Juice; Gastric Mucosa | 1972 |
Aspirin: the unique drug.
Topics: Aspirin; Blood Platelets; Drug Interactions; Drug Synergism; Gastrointestinal Hemorrhage; Hemorrhage | 1974 |
Gastrointestinal hemorrhage. I. General considerations of diagnosis and the rapy.
Topics: Anus Diseases; Aspirin; Biliary Tract Diseases; Blood Coagulation Disorders; Burns; Child; Child, Pr | 1973 |
The gut and arthritis.
Topics: Adrenal Cortex Hormones; Analgesics; Anti-Inflammatory Agents; Arthritis, Infectious; Arthritis, Rhe | 1974 |
Gastritis.
Topics: Animals; Aspirin; Atropine; Bile Acids and Salts; Cell Membrane Permeability; Ethanol; Gastric Juice | 1974 |
Septic shock and disturbances in coagulation.
Topics: Acidosis; Acute Kidney Injury; Aminocaproates; Aspirin; Blood Coagulation Disorders; Blood Coagulati | 1974 |
Gastric mucosal injury by anti-inflammatory drugs.
Topics: Acute Disease; Anti-Inflammatory Agents; Aspirin; Chronic Disease; Epithelial Cells; Epithelium; Gas | 1974 |
Telangiectasia: its relationship to the Minot-von Willebrand syndrome.
Topics: Adolescent; Adult; Aspirin; Blood Coagulation Tests; Child; Child, Preschool; Epistaxis; Female; Gas | 1967 |
Gastroenterology in Australia, 1949-69.
Topics: Animals; Aspirin; Australia; Colitis, Ulcerative; Copper; Gastric Juice; Gastroenterology; Gastroint | 1970 |
Epidemiological evidence for the association of aspirin and acute gastrointestinal bleeding.
Topics: Alcohol Drinking; Animals; Ascorbic Acid Deficiency; Aspirin; Gastrointestinal Hemorrhage; Hematemes | 1970 |
Aspirin, ethanol and the stomach.
Topics: Absorption; Aspirin; Ethanol; Gastric Juice; Gastritis; Gastrointestinal Hemorrhage; Humans; Peptic | 1970 |
[Gastrointestinal bleeding following ingestion of salicylates].
Topics: Animals; Anticoagulants; Ascorbic Acid Deficiency; Aspirin; Cats; Gastric Juice; Gastric Mucosa; Gas | 1971 |
Acute haemorrhagic gastritis: modern concepts based on pathogenesis.
Topics: Acute Disease; Aspirin; Blood Transfusion; Cell Membrane Permeability; Endoscopy; Gastrectomy; Gastr | 1971 |
[Aspirin and gastric hemorrhage].
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Stomach Diseases | 1970 |
Aspirin and gastrointestinal bleeding.
Topics: Animals; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans | 1968 |
178 trials available for aspirin and Gastrointestinal Hemorrhage
| Article | Year |
|---|---|
Magnetically Controlled Capsule Endoscopy for Assessment of Antiplatelet Therapy-Induced Gastrointestinal Injury.
Topics: Aged; Aspirin; Capsule Endoscopy; Clopidogrel; Dual Anti-Platelet Therapy; Female; Gastric Mucosa; G | 2022 |
Proton pump inhibitor in the prevention of upper gastrointestinal mucosal injury associated with dual antiplatelet therapy after coronary artery bypass grafting (DACAB-GI-2): study protocol for a randomized controlled trial.
Topics: Aspirin; Coronary Artery Bypass; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Pan | 2022 |
Time of Resumption of Antiplatelet Drugs After Upper Gastrointestinal Hemorrhage.
Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggre | 2022 |
Reliability of major bleeding events in UK routine data versus clinical trial adjudicated follow-up data.
Topics: Aspirin; Diabetes Mellitus; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Reproduc | 2023 |
Effectiveness and Safety of Enteric-Coated vs Uncoated Aspirin in Patients With Cardiovascular Disease: A Secondary Analysis of the ADAPTABLE Randomized Clinical Trial.
Topics: Aged; Aspirin; Cardiovascular Diseases; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Ma | 2023 |
Clinical, clinicopathologic, and gastrointestinal changes from aspirin, prednisone, or combination treatment in healthy research dogs: A double-blind randomized trial.
Topics: Administration, Oral; Animals; Aspirin; Dogs; Double-Blind Method; Drug Therapy, Combination; Female | 2019 |
Bleeding and New Cancer Diagnosis in Patients With Atherosclerosis.
Topics: Aged; Aspirin; Atherosclerosis; Coronary Artery Disease; Drug Therapy, Combination; Female; Gastroin | 2019 |
Bleeding and New Cancer Diagnosis in Patients With Atherosclerosis.
Topics: Aged; Aspirin; Atherosclerosis; Coronary Artery Disease; Drug Therapy, Combination; Female; Gastroin | 2019 |
Bleeding and New Cancer Diagnosis in Patients With Atherosclerosis.
Topics: Aged; Aspirin; Atherosclerosis; Coronary Artery Disease; Drug Therapy, Combination; Female; Gastroin | 2019 |
Bleeding and New Cancer Diagnosis in Patients With Atherosclerosis.
Topics: Aged; Aspirin; Atherosclerosis; Coronary Artery Disease; Drug Therapy, Combination; Female; Gastroin | 2019 |
An investigation into the impact of enteric coated of aspirin in patients with newly diagnosed ischemic stroke (ECASIS).
Topics: Adolescent; Adult; Aged; Aspirin; Blood Platelets; Brain Ischemia; Female; Gastrointestinal Hemorrha | 2020 |
Bleeding associated with low-dose aspirin: Comparison of data from the COMPASS randomized controlled trial and routine clinical practice.
Topics: Aspirin; Cohort Studies; Gastrointestinal Hemorrhage; Humans; Incidence; Intracranial Hemorrhages | 2020 |
Optimal antiplatelet therapy for prevention of gastrointestinal injury evaluated by ANKON magnetically controlled capsule endoscopy: Rationale and design of the OPT-PEACE trial.
Topics: Adult; Aspirin; Capsule Endoscopy; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Doubl | 2020 |
Major GI bleeding in older persons using aspirin: incidence and risk factors in the ASPREE randomised controlled trial.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Australia; Double-Blind M | 2021 |
Omeprazole vs famotidine for the prevention of gastroduodenal injury in high-risk users of low-dose aspirin: A randomized controlled trial.
Topics: Aged; Aged, 80 and over; Aspirin; Famotidine; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; H | 2021 |
Effect of a proton-pump inhibitor on intestinal microbiota in patients taking low-dose aspirin.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Com | 2021 |
Aspirin and gastrointestinal bleeding risk in older people.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; | 2021 |
Aspirin wears smart.
Topics: Administration, Sublingual; Animals; Aspirin; Biomarkers; Collagen; Double-Blind Method; Drug Compou | 2017 |
Rationale and Design for a Randomized Comparison of Efficacy and Safety between Aspirin and Clopidogrel in Atrial Fibrillation Patients with Low Stroke Risk: CESAC-AF trial.
Topics: Aspirin; Atrial Fibrillation; Clopidogrel; Drug Therapy, Combination; Endoscopy, Digestive System; G | 2017 |
Vonoprazan prevents low-dose aspirin-associated ulcer recurrence: randomised phase 3 study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Double | 2018 |
Vonoprazan prevents low-dose aspirin-associated ulcer recurrence: randomised phase 3 study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Double | 2018 |
Vonoprazan prevents low-dose aspirin-associated ulcer recurrence: randomised phase 3 study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Double | 2018 |
Vonoprazan prevents low-dose aspirin-associated ulcer recurrence: randomised phase 3 study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Double | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Gastrointestinal Hemorrhage; Humans; Intention to Treat | 2018 |
Risk for Major Hemorrhages in Patients Receiving Clopidogrel and Aspirin Compared With Aspirin Alone After Transient Ischemic Attack or Minor Ischemic Stroke: A Secondary Analysis of the POINT Randomized Clinical Trial.
Topics: Aged; Aspirin; Brain Ischemia; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Female; | 2019 |
Pantoprazole to Prevent Gastroduodenal Events in Patients Receiving Rivaroxaban and/or Aspirin in a Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Administration, Oral; Aged; Anticoagulants; Aspirin; Cardiovascular Diseases; Dose-Response Relation | 2019 |
Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin.
Topics: Aged; Aspirin; Cardiovascular Diseases; Double-Blind Method; Drug Administration Schedule; Enterocol | 2019 |
Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin.
Topics: Aged; Aspirin; Cardiovascular Diseases; Double-Blind Method; Drug Administration Schedule; Enterocol | 2019 |
Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin.
Topics: Aged; Aspirin; Cardiovascular Diseases; Double-Blind Method; Drug Administration Schedule; Enterocol | 2019 |
Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin.
Topics: Aged; Aspirin; Cardiovascular Diseases; Double-Blind Method; Drug Administration Schedule; Enterocol | 2019 |
Study design of ASPirin in Reducing Events in the Elderly (ASPREE): a randomized, controlled trial.
Topics: Activities of Daily Living; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Australia; Cardi | 2013 |
Effect of clopidogrel with or without omeprazole in patients with carotid artery stenting.
Topics: Angiography; Aspirin; Breath Tests; Carotid Arteries; Carotid Stenosis; Clopidogrel; Drug Interactio | 2013 |
A randomized, double-blind, placebo-controlled study of rebamipide for gastric mucosal injury taking aspirin with or without clopidogrel.
Topics: Adult; Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Double-Blind Method; Gastric Mucosa; Gastro | 2014 |
Individualised prediction of alternate-day aspirin treatment effects on the combined risk of cancer, cardiovascular disease and gastrointestinal bleeding in healthy women.
Topics: Age Factors; Aged; Aspirin; Cardiovascular Diseases; Decision Support Techniques; Drug Administratio | 2015 |
Frequency and practice-level variation in inappropriate aspirin use for the primary prevention of cardiovascular disease: insights from the National Cardiovascular Disease Registry's Practice Innovation and Clinical Excellence registry.
Topics: Aged; Aspirin; Cardiovascular Diseases; Confidence Intervals; Female; Fibrinolytic Agents; Follow-Up | 2015 |
The effects of proton pump inhibition on patient-reported severity of dyspepsia when receiving dual anti-platelet therapy with clopidogrel and low-dose aspirin: analysis from the Clopidogrel and the Optimization of Gastrointestinal Events Trial.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Double-Blind Method; Drug The | 2015 |
Proton-Pump Inhibitors Reduce Gastrointestinal Events Regardless of Aspirin Dose in Patients Requiring Dual Antiplatelet Therapy.
Topics: Aged; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyspepsia; | 2016 |
Efficacy and Safety of Proton-Pump Inhibitors in High-Risk Cardiovascular Subsets of the COGENT Trial.
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Double-Blind Method; Drug Therapy, Combination; Gastr | 2016 |
ADD-ASPIRIN: A phase III, double-blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Breast Neoplasms; Chemotherapy, Adjuvant; Colorect | 2016 |
Bleeding risk associated with 1 year of dual antiplatelet therapy after percutaneous coronary intervention: Insights from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Therapy, C | 2009 |
Bleeding increases the risk of ischemic events in patients with peripheral arterial disease.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cerebral Hemorrhage; Confide | 2009 |
Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non- | 2010 |
Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non- | 2010 |
Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non- | 2010 |
Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non- | 2010 |
Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Ster | 2010 |
Is gastroduodenal biopsy safe in patients receiving aspirin and clopidogrel?: a prospective, randomized study involving 630 biopsies.
Topics: Adult; Aspirin; Biopsy; Clopidogrel; Duodenum; Endoscopy, Digestive System; Female; Gastrointestinal | 2011 |
Clopidogrel with or without omeprazole in coronary artery disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Dru | 2010 |
Clopidogrel with or without omeprazole in coronary artery disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Dru | 2010 |
Clopidogrel with or without omeprazole in coronary artery disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Dru | 2010 |
Clopidogrel with or without omeprazole in coronary artery disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Dru | 2010 |
Clopidogrel with or without omeprazole in coronary artery disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Dru | 2010 |
Clopidogrel with or without omeprazole in coronary artery disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Dru | 2010 |
Clopidogrel with or without omeprazole in coronary artery disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Dru | 2010 |
Clopidogrel with or without omeprazole in coronary artery disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Dru | 2010 |
Clopidogrel with or without omeprazole in coronary artery disease.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Coronary Artery Disease; Drug Interactions; Dru | 2010 |
Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarction.
Topics: Acute Coronary Syndrome; Aged; Anti-Ulcer Agents; Aspirin; Chi-Square Distribution; Clopidogrel; Dou | 2012 |
Effects of pantoprazole on dual antiplatelet therapy in stable angina pectoris patients after percutaneous coronary intervention.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Angina, Stable; Angioplasty, Balloon, Coronary; Aspirin; Cl | 2012 |
A critical review of selective serotonin reuptake inhibitor-associated bleeding: balancing the risk of treating hepatitis C-infected patients.
Topics: Analgesics; Antidepressive Agents; Antiviral Agents; Aspirin; Depressive Disorder; Drug Interactions | 2003 |
Effects of buffered and plain acetylsalicylic acid formulations with and without ascorbic acid on gastric mucosa in healthy subjects.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Aspirin; Cross-Over Stu | 2004 |
A prospective study of same day bi-directional endoscopy in the evaluation of patients with occult gastrointestinal bleeding.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Endoscopy, Gastroi | 2006 |
Does adding misoprostol to standard intravenous proton pump inhibitor protocol improve the outcome of aspirin/NSAID-induced upper gastrointestinal bleeding?: a randomized prospective study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer A | 2007 |
Continuing or discontinuing low-dose aspirin before transrectal prostate biopsy: results of a prospective randomized trial.
Topics: Aged; Aspirin; Biopsy, Needle; Follow-Up Studies; Gastrointestinal Hemorrhage; Hematuria; Hemospermi | 2007 |
Evaluation of proton pump inhibitor use in patients with acute coronary syndromes based on risk factors for gastrointestinal bleed.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Female; Fibrinolytic Agents; Gastrointestinal H | 2007 |
Etodolac, aspirin, and gastrointestinal microbleeding.
Topics: Acetates; Adult; Aspirin; Dose-Response Relationship, Drug; Drug Evaluation; Etodolac; Gastrointesti | 1984 |
Gastro-intestinal blood loss with high dose tilcotil (Ro 12-0068) and aspirin: an open crossover clinical trial and pharmacokinetic assessment in normal volunteers.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Dose-Response Rel | 1983 |
Prevention of acute aspirin-induced gastric mucosal injury by 15-R-15 methyl prostaglandin E2: an endoscopic study.
Topics: Adolescent; Adult; Arbaprostil; Aspirin; Clinical Trials as Topic; Dose-Response Relationship, Drug; | 1984 |
[Prostaglandin E1 (misoprostol) and S-adenosylmethionine in the prevention of hemorrhagic gastritis induced by aspirin in the human. Endoscopic, histologic and histochemical study].
Topics: Adult; Alprostadil; Aspirin; Clinical Trials as Topic; Double-Blind Method; Duodenum; Female; Gastri | 1984 |
Gastric adaptation occurs with aspirin administration in man.
Topics: Adult; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Male; Time Factors | 1983 |
Gastric bleeding and gastric secretion with sulindac and naproxen.
Topics: Aspirin; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Indenes; Intestinal Abso | 1983 |
Faecal blood loss during administration of acetylsalicylic acid, ketoprofen and two new ketoprofen sustained-release compounds.
Topics: Adult; Aspirin; Capsules; Delayed-Action Preparations; Gastrointestinal Hemorrhage; Humans; Ketoprof | 1983 |
Comparative study of gastrointestinal microbleeding caused by aspirin, fenbufen, and placebo.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Aspirin; Dose-Response Relationship, Drug; Drug Evaluat | 1983 |
[Gastric microhemorrhage and acetylsalicylic acid. Prevention using prostaglandin E2].
Topics: Adolescent; Adult; Aspirin; Dinoprostone; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Prost | 1983 |
Fecal blood loss caused by two differently microencapsulated acetylsalicylic acid preparations in patients with rheumatoid arthritis. A prospective crossover study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Delayed-Action Preparations; | 1982 |
Effect of prostaglandin E2 on gastric mucosal bleeding caused by aspirin.
Topics: Aspirin; Chlorides; Double-Blind Method; Gastric Juice; Gastric Mucosa; Gastrointestinal Hemorrhage; | 1981 |
Protection against aspirin-induced blood loss in man: assessment of a new mucolytic agent.
Topics: Adult; Aniline Compounds; Aspirin; Expectorants; Gastrointestinal Hemorrhage; Humans; Middle Aged | 1981 |
Effects of diflunisal on platelet function and fecal blood loss.
Topics: Adult; Aspirin; Blood Platelets; Diflunisal; Double-Blind Method; Feces; Female; Gastrointestinal He | 1981 |
Enteric-coated pelletized aspirin. Gastrointestinal blood loss and bioavailability.
Topics: Aspirin; Biological Availability; Gastrointestinal Hemorrhage; Humans; Salicylates; Tablets, Enteric | 1981 |
Gastrointestinal blood loss, gastroscopy and coagulation factors in normal volunteers during administration of acetylsalicylic acid and fluproquazone.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Tests; Feces; | 1981 |
Gastrointestinal blood loss of oxaprozin and aspirin with placebo control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Double-Blind Method; Feces; Gastrointestinal Hemor | 1982 |
A comparison between gastrointestinal blood loss caused by tilcotil (Ro 12-0068) and aspirin in normal volunteers.
Topics: Acetylglucosaminidase; Adult; Anti-Inflammatory Agents; Aspirin; Female; Gastrointestinal Hemorrhage | 1982 |
Prostaglandin E2 tablets prevent aspirin-induced blood loss in man.
Topics: Adolescent; Adult; Aspirin; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Male; Prostagl | 1982 |
Prevention of aspirin-induced fecal blood loss in men with prostaglandin E2.
Topics: Administration, Oral; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Gastrointestina | 1980 |
Long-term safety of benoxaprofen.
Topics: Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzoxazoles; Blood Urea Nitrogen; C | 1980 |
Gastrointestinal microbleeding: comparisons between benoxaprofen and other nonsteroidal antiinflammatory agents.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzoxazoles; Clinical Trials as Topic; Do | 1980 |
Prevention of aspirin-induced faecal blood loss by prostaglandin E2.
Topics: Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Feces; Gastrointestinal Hemorrhage; H | 1980 |
Comparison of serum salicylate levels and gastro-intestinal blood loss between salsalate (Disalcid)and other forms of salicylates.
Topics: Aspirin; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhage; Humans; Male; Salicylates | 1981 |
Prevention of aspirin-induced fecal blood loss with oral prostaglandin E2: dose-response studies in man.
Topics: Adult; Aspirin; Clinical Trials as Topic; Dinoprostone; Dose-Response Relationship, Drug; Double-Bli | 1981 |
Risks of gastrointestinal bleeding during secondary prevention of vascular events with aspirin--analysis of gastrointestinal bleeding during the UK-TIA trial.
Topics: Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Humans; Ischemic Attack, Tra | 1995 |
Gastrointestinal blood loss with low dose (325 mg) plain and enteric-coated aspirin administration.
Topics: Adaptation, Physiological; Adult; Aspirin; Cross-Over Studies; Female; Gastrointestinal Hemorrhage; | 1995 |
Gastrointestinal blood loss induced by three different non-steroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromium Radioisotopes; Clonixin; Cyclooxyge | 1995 |
Ranitidine bismuth citrate and aspirin-induced gastric mucosal injury.
Topics: Adult; Aspirin; Bismuth; Citrates; Double-Blind Method; Duodenum; Gastric Mucosa; Gastrointestinal H | 1993 |
Effects of ibuprofen lysinate and acetylsalicylic acid on gastric and duodenal mucosa. Randomized single-blind placebo-controlled endoscopic study in healthy volunteers.
Topics: Adult; Aspirin; Duodenum; Endoscopy; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Ibuprofen; | 1994 |
Low-dose aspirin and incidence of colorectal tumors in a randomized trial.
Topics: Adult; Aged; Aspirin; Colorectal Neoplasms; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; | 1993 |
Use of synthetic prostaglandin E1 (misoprostol) for prevention of aspirin-induced gastroduodenal ulceration in arthritic dogs.
Topics: Animals; Aspirin; Diarrhea; Dog Diseases; Dogs; Double-Blind Method; Duodenoscopy; Female; Gastroint | 1993 |
Nonsteroidal anti-inflammatory drug use in relation to major upper gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Dic | 1993 |
Fecal hemoglobin excretion in elderly patients with atrial fibrillation: combined aspirin and low-dose warfarin vs conventional warfarin therapy.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Drug Therapy, Combination; Fe | 1996 |
Risk of aspirin-associated major upper-gastrointestinal bleeding with enteric-coated or buffered product.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Buffers; Case-Control Stu | 1996 |
Low-intensity oral anticoagulation plus low-dose aspirin versus high-intensity oral anticoagulation alone: a randomized trial in patients with mechanical prosthetic heart valves.
Topics: Anticoagulants; Aspirin; Coumarins; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; | 1997 |
Effect of sucralfate on aspirin induced mucosal injury and impaired haemostasis in humans.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Biopsy; Cross-Ov | 1997 |
Risk of major gastrointestinal bleeding with aspirin.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebrovascular Disorders; Delayed-Action Pr | 1999 |
[Lowering of diastolic blood pressure < or = 90 mmHg should not be attempted, except in type 2 diabetics; the 'Hypertension optimal treatment' (HOT) trial].
Topics: Adult; Aged; Aspirin; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Me | 1999 |
Non-steroidal anti-inflammatory drugs, Helicobacter pylori and bleeding gastric ulcer.
Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointestinal | 2000 |
Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulations.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Chemistry, Phar | 2001 |
Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Drug The | 2001 |
Effect of nabumetone and aspirin on colonic mucosal bleeding time.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Butanones; Co | 2001 |
Comparative tolerability of paracetamol, aspirin and ibuprofen for short-term analgesia in patients with musculoskeletal conditions: results in 4291 patients.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Female; Ga | 2002 |
[Application of quantifying scoring systems for the determination of changes in the mucosa of the upper gastrointestinal tract. A comparative study of a diclofenac effervescent tablet with conventional diclofenac preparations and acetylsalicylic acid afte
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Drug Combinations; Endoscopy; F | 2002 |
Aspirin, paracetamol, diflunisal, and gastrointestinal blood-loss.
Topics: Acetaminophen; Aspirin; Gastrointestinal Hemorrhage; Humans; Salicylates | 1979 |
Gastrointestinal blood loss. Effect of aspirin, fenoprofen, and acetaminophen in rheumatoid arthritis as determined by sequential gastroscopy and radioactive fecal markers.
Topics: Acetaminophen; Aged; Arthritis, Rheumatoid; Aspirin; Autoradiography; Blood Specimen Collection; Fem | 1977 |
Fecal blood loss and plasma salicylate study of salicylsalicylic acid and aspirin.
Topics: Adult; Aspirin; Chromium Radioisotopes; Female; Gastrointestinal Hemorrhage; Humans; Liver; Male; Pl | 1979 |
A procedure for measuring gastric bleeding caused by drugs.
Topics: Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Male; Methods | 1979 |
Gastro-intestinal blood loss during administration of indoprofen, aspirin and ibuprofen.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Dose-Respon | 1977 |
Estimation of gastro-intestinal blood loss in volunteers treated with non-steroidal anti-inflammatory agents.
Topics: Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Feces; Flurbiprofen; Gastrointestinal | 1977 |
[Acetylsalicylic acid and gastrointestinal bleeding--a study of blood loss and absorption after intake of a gastric juice--resistant preparation].
Topics: Adult; Aspirin; Clinical Trials as Topic; Drug Evaluation; Gastric Juice; Gastrointestinal Hemorrhag | 1977 |
Reduction of aspirin-induced gastrointestinal bleeding with cimetidine.
Topics: Arthritis; Aspirin; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Gastric Juice; Gastro | 1978 |
Gastric mucosal damage caused by plain and microencapsulated acetylsalicylic acid tablets in healthy subjects: a gastrocamera study.
Topics: Adult; Aspirin; Clinical Trials as Topic; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastr | 1977 |
Gastrointestinal microbleeding after aspirin and naproxen.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; | 1978 |
Gastrointestinal blood loss after diflunisal and after aspirin: effect of ethanol.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Double-Blind Meth | 1978 |
The effects of enteric coating of aspirin tablets on occult gastrointestinal blood loss.
Topics: Aged; Aspirin; Biological Availability; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhag | 1977 |
Comparision of low dose heparin and low dose heparin combined with aspirin in prevention of deep vein thrombosis after total hip replacement.
Topics: Aspirin; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Heparin; Humans; Joint Pros | 1977 |
Comparison of gastrointestinal effects of aspirin and fenoprofen. A double blind crossover study.
Topics: Administration, Oral; Adult; Aspirin; Clinical Trials as Topic; Duodenum; Endoscopy; Fenoprofen; Gas | 1979 |
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as | 1979 |
Gastrointestinal blood loss caused by controlled-release and conventional acetylsalicylic acid tablets.
Topics: Adult; Aspirin; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Feces; Gas | 1979 |
[Buffered and unbuffered acetylsalicylic acid].
Topics: Aspirin; Buffers; Clinical Trials as Topic; Drug Evaluation; Gastrointestinal Hemorrhage; Humans; Ta | 1976 |
Double-blind study of Naproxen in osteoarthritis of the knee joint.
Topics: Activities of Daily Living; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; C | 1976 |
Clinical pharmacology of fenoprofen: a review.
Topics: Animals; Aspirin; Clinical Trials as Topic; Erythema; Fenoprofen; Fever; Gastrointestinal Hemorrhage | 1976 |
Gastrointestinal blood loss induced by ketoprofen, aspirin and placebo (preliminary report).
Topics: Adult; Analgesics; Aspirin; Benzophenones; Clinical Trials as Topic; Drug Evaluation; Gastrointestin | 1976 |
Aspirin revisited.
Topics: Animals; Aspirin; Blood Platelets; Clinical Trials as Topic; Gastrointestinal Hemorrhage; Hemostasis | 1975 |
Effect of naproxen on gastrointestinal microbleeding following acetylsalicylate medication.
Topics: Analysis of Variance; Anti-Inflammatory Agents; Aspirin; Gastrointestinal Hemorrhage; Humans; Naphth | 1975 |
Intestinal blood loss after a new anti-inflammatory drug, sulindac.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Benzylidene Compounds; Chromium Radioisotopes; Erythrocyte | 1976 |
A comparative blood loss study of floctafenine and aspirin in normal subjects.
Topics: Adolescent; Adult; Analgesics; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhag | 1976 |
Gastro-intestinal microbleeding under acetylsalicylic acid, ketoprofen and placebo.
Topics: Anti-Inflammatory Agents; Aspirin; Benzophenones; Gastrointestinal Hemorrhage; Humans; Ketoprofen; M | 1976 |
Acetylsalicylic acid and gastrointestinal bleeding measurement of blood loss using a modified radioactive chromium method.
Topics: Administration, Oral; Adult; Aspirin; Buffers; Chromium Radioisotopes; Clinical Trials as Topic; Fec | 1975 |
Ranitidine: differential effects on gastric bleeding and mucosal damage induced by aspirin.
Topics: Adult; Aspirin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gastric Mucosa; Gastr | 1992 |
Gastrointestinal blood loss after non-steroidal anti-inflammatory drugs. Measurement by selective determination of faecal porphyrins.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzidines; Chromium Radioisotopes; Feces; | 1992 |
Separation of the impairment of haemostasis by aspirin from mucosal injury in the human stomach.
Topics: Adult; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Drug Administration Schedule; Female | 1991 |
Upper gastrointestinal bleeding in relation to previous use of analgesics and non-steroidal anti-inflammatory drugs. Catalan Countries Study on Upper Gastrointestinal Bleeding.
Topics: Adult; Age Factors; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control | 1991 |
A double blind randomized placebo-controlled study demonstrates the protective efficacy of rosaprostol on aspirin-induced gastrointestinal bleeding in man.
Topics: Adult; Anti-Ulcer Agents; Aspirin; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Male; O | 1991 |
Gastric protection by nocloprost against aspirin damage in humans. Possible role of epidermal growth factor.
Topics: Adult; Aspirin; Double-Blind Method; Epidermal Growth Factor; Gastric Acid; Gastric Mucosa; Gastroin | 1991 |
Relation of upper gastrointestinal bleeding to non-steroidal anti-inflammatory drugs and aspirin: a case-control study.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control | 1991 |
Aspirin-induced gastric mucosal damage: prevention by enteric-coating and relation to prostaglandin synthesis.
Topics: Adult; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gastric | 1991 |
Combined aspirin and sulfinpyrazone in the prevention of recurrent hemodialysis vascular access thrombosis.
Topics: Aspirin; Blood Coagulation Tests; Blood Platelets; Catheters, Indwelling; Drug Evaluation; Drug Ther | 1991 |
Effect of Helicobacter pylori infection on the severity of gastroduodenal mucosal injury after the acute administration of naproxen or aspirin to normal volunteers.
Topics: Adult; Aspirin; Duodenal Ulcer; Duodenum; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Helic | 1991 |
Abolition by omeprazole of aspirin induced gastric mucosal injury in man.
Topics: Adult; Aspirin; Double-Blind Method; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Ga | 1990 |
Human gastric mucosal bleeding induced by low dose aspirin, but not warfarin.
Topics: Adult; Aspirin; Cohort Studies; Drug Synergism; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; | 1989 |
Protective effect of low dose of enprostil against gastric blood loss induced by aspirin in man.
Topics: Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Enprostil; Female; Gastric Acid; Gast | 1989 |
Use of microbleeding and an ultrathin endoscope to assess gastric mucosal protection by famotidine.
Topics: Adolescent; Adult; Aspirin; Double-Blind Method; Famotidine; Female; Gastric Mucosa; Gastrointestina | 1989 |
[Effect of somatostatin and ranitidine in acute hemorrhage of the upper digestive tract].
Topics: Acute Disease; Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Female; Gastritis; Gastro | 1989 |
Enhanced gastric mucosal bleeding with doses of aspirin used for prophylaxis and its reduction by ranitidine.
Topics: Adult; Aspirin; Female; Gastric Acid; Gastrointestinal Hemorrhage; Humans; Male; Ranitidine | 1989 |
[Ranitidine protects the human stomach and duodenal mucosa against low-dose acetylsalicylic acid].
Topics: Adult; Aspirin; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ga | 1989 |
Comparative gastrointestinal blood loss associated with placebo, aspirin, and nabumetone as assessed by radiochromium (51Cr).
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Chromium Radioisotopes; Double-B | 1989 |
The effects of flurbiprofen, aspirin, cimetidine, and antacids on the gastric and duodenal mucosa of normal volunteers. An endoscopic and photographic study.
Topics: Adult; Antacids; Aspirin; Cimetidine; Duodenum; Endoscopy; Female; Flurbiprofen; Gastric Mucosa; Gas | 1989 |
Gastrointestinal blood loss from a new buffered aspirin (Ostoprin): measurement by radiochromium and Hemoquant techniques.
Topics: Adolescent; Adult; Aged; Aspirin; Chromium Radioisotopes; Female; Gastrointestinal Hemorrhage; Heme; | 1989 |
Failure of ethamsylate to reduce aspirin-induced gastric mucosal bleeding in humans.
Topics: Adult; Aspirin; Benzenesulfonates; Ethamsylate; Female; Gastric Juice; Gastric Mucosa; Gastrointesti | 1989 |
Etodolac compared with aspirin: an endoscopic study of the gastrointestinal tracts of normal volunteers.
Topics: Acetates; Adolescent; Adult; Aspirin; Dose-Response Relationship, Drug; Duodenitis; Endoscopy; Etodo | 1986 |
Double-blind placebo-controlled study on the effect of sucralfate on gastric biosynthesis of prostaglandin in normal and aspirin-treated humans.
Topics: Adult; Aspirin; Double-Blind Method; Drug Evaluation; Gastric Mucosa; Gastrointestinal Hemorrhage; H | 1987 |
Effects of colloidal bismuth subcitrate on aspirin-induced gastric microbleeding, DNA loss, and prostaglandin formation in humans.
Topics: Anti-Ulcer Agents; Aspirin; Clinical Trials as Topic; Dinoprostone; DNA; Double-Blind Method; Gastri | 1988 |
Reduction by enprostil of aspirin-induced blood loss from human gastric mucosa.
Topics: Adult; Aspirin; Capsules; Clinical Trials as Topic; Double-Blind Method; Enprostil; Gastric Mucosa; | 1986 |
Protective effect of enprostil against aspirin-induced gastroduodenal mucosal injury in man. Comparison with cimetidine and sucralfate.
Topics: Adult; Aluminum; Aspirin; Cimetidine; Clinical Trials as Topic; Duodenum; Enprostil; Gastric Mucosa; | 1986 |
Effect of red pepper and black pepper on the stomach.
Topics: Adult; Aspirin; Capsicum; Condiments; DNA; Dose-Response Relationship, Drug; Double-Blind Method; Fe | 1987 |
Role of misoprostol in reducing aspirin-induced gastrointestinal blood loss in arthritic patients.
Topics: Alprostadil; Anti-Ulcer Agents; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle A | 1987 |
Role of H2-receptor blockers in the prevention of gastric injury resulting from nonsteroidal anti-inflammatory agents.
Topics: Aspirin; Cimetidine; Double-Blind Method; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; | 1988 |
Effect in man of aspirin, standard indomethacin, and sustained release indomethacin preparations on gastric bleeding.
Topics: Adolescent; Adult; Aspirin; Delayed-Action Preparations; Female; Gastric Acid; Gastrointestinal Hemo | 1988 |
Reduction of endoscopically assessed acute aspirin-induced gastric mucosal injury with cimetidine.
Topics: Acute Disease; Adolescent; Adult; Aspirin; Cimetidine; Clinical Trials as Topic; Dose-Response Relat | 1987 |
Non-steroidal anti-inflammatory drugs (NSAIDs) cause gastrointestinal intolerance and major bleeding--or do they?
Topics: Administration, Rectal; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as T | 1987 |
Does sucralfate reduce acetylsalicylic-acid-induced gastric mucosal bleeding?
Topics: Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; | 1987 |
Gastroprotection by sucralfate against acetylsalicylic acid in humans. Role of endogenous prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Clinical Trials as Topic; Dinoprostone; DNA; Double-Bl | 1987 |
Double blind controlled study on the effect of sucralfate on gastric prostaglandin formation and microbleeding in normal and aspirin treated man.
Topics: Adult; Aspirin; DNA; Double-Blind Method; Drug Evaluation; Gastric Acid; Gastric Mucosa; Gastrointes | 1986 |
Radiochromium (chromium-51) evaluation of gastrointestinal blood loss associated with placebo, aspirin, and nabumetone.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Chromium Radioisotopes; Double-B | 1987 |
Effects of aspirin and an aspirin-acetaminophen combination on the gastric mucosa in normal subjects. A double-blind endoscopic study.
Topics: Acetaminophen; Adult; Aspirin; Double-Blind Method; Drug Administration Schedule; Drug Combinations; | 1985 |
Nonsteroidal anti-inflammatory effect of sulindac sulfoxide and sulfide on gastric mucosa.
Topics: Administration, Oral; Adult; Aspirin; Double-Blind Method; Gastric Mucosa; Gastrointestinal Hemorrha | 1985 |
Reduction of aspirin-induced fecal blood loss with low-dose misoprostol tablets in man.
Topics: Adult; Aspirin; Chromium Radioisotopes; Double-Blind Method; Drug Evaluation; Feces; Gastrointestina | 1985 |
Gastrointestinal cytoprotective effects of misoprostol. Clinical efficacy overview.
Topics: Adult; Alprostadil; Anti-Ulcer Agents; Aspirin; Bile Acids and Salts; DNA; Drug Evaluation; Duodenum | 1985 |
Impaired platelet-connective-tissue reaction in man after aspirin ingestion.
Topics: Adenine Nucleotides; Adult; Aspirin; Blood Platelets; Connective Tissue; Gastrointestinal Hemorrhage | 1967 |
Effect of particle size on aspirin-induced gastrointestinal bleeding.
Topics: Adult; Aspirin; Capsules; Female; Gastrointestinal Hemorrhage; Gelatin; Humans; Male; Occult Blood | 1968 |
Determination of faecal blood-loss after combined alcohol and sodium-acetylsalicylate intake.
Topics: Aspirin; Buffers; Chromium Isotopes; Clinical Trials as Topic; Ethanol; Gastric Mucosa; Gastrointest | 1969 |
Faecal blood-loss after sodium acetylsalicylate taken with alcohol.
Topics: Aspirin; Clinical Trials as Topic; Ethanol; Gastrointestinal Hemorrhage; Humans; Melena; Placebos | 1969 |
Gastrointestinal blood loss in patients receiving acetylsalicylic acid or diftalone, a new antiinflammatory drug: a comparative evaluation.
Topics: Administration, Oral; Adolescent; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents; Aspir | 1974 |
Absence of gastrointestinal bleeding with controlled-release potassium chloride tablets.
Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Aspirin; Chromium Radioisotopes; Dela | 1974 |
Comparison of aspirin and benorylate in the treatment of rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Analgesics; Aniline Compounds; Anti-Inflammatory Agents; Arthritis, Rheumat | 1972 |
Comparative effects of aspirin and naproxen on gastric mucosa.
Topics: Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Drug Evaluation; Gastric Mucosa; Gastro | 1973 |
Effects of in vitro aspirin on blood platelets of gastrointestinal bleeders.
Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Blood Platelets; Clinical Trials as Topic; Collagen; De | 1974 |
Effect of naproxen and of aspirin on bleeding time and platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Aspirin; Blood Cell Count; Blood Coagulation; Cl | 1974 |
Analgesic drugs in the cat.
Topics: Analgesia; Analgesics; Animals; Aspirin; Cats; Chlorpromazine; Clinical Trials as Topic; Dextropropo | 1968 |
The effect of food on aspirin induced gastro-intestinal blood loss.
Topics: Aspirin; Chromium Isotopes; Clinical Trials as Topic; Feces; Food; Gastrointestinal Hemorrhage; Huma | 1968 |
Ibuprofen, aspirin and placebo in the treatment of rheumatoid arthritis--a double-blind clinical trial.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials a | 1969 |
Absence of gastrointestinal bleeding following administration of salicylsalicylic acid.
Topics: Adult; Aspirin; Chromium Isotopes; Clinical Trials as Topic; Feces; Female; Gastrointestinal Hemorrh | 1969 |
Effects of salicylates on the gastric mucosa as revealed by roentgen examination and the gastrocamera.
Topics: Aspirin; Clinical Trials as Topic; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Heartbu | 1971 |
A method of evaluation of the influence of aspirin formulations on gastrointestinal microbleeding in humans.
Topics: Adult; Aspirin; Chromium Isotopes; Clinical Trials as Topic; Drug Compounding; Evaluation Studies as | 1971 |
Double-blind comparison of effects of aspirin and namoxyrate on pH of gastric secretions, fecal blood loss, serum iron, and iron-binding capacity in normal volunteers.
Topics: Adult; Analgesics; Aspirin; Blood; Clinical Trials as Topic; Gastric Acidity Determination; Gastric | 1965 |
[Long-term study on gastrointestinal hemorrhage due to acetylsalicylic acid].
Topics: Adult; Aspirin; Blood Volume; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Iron Isotopes; | 1971 |
Gastric mucosa and susceptibility to occult gastrointestinal bleeding caused by aspirin.
Topics: Adult; Aspirin; DNA; Female; Gastrectomy; Gastric Lavage; Gastric Mucosa; Gastrointestinal Hemorrhag | 1967 |
Effect of salicylates on gastrointestinal protein loss in normal subjects.
Topics: Adult; Aged; Aluminum; Aspirin; Caffeine; Carbonates; Chromium Isotopes; Citrates; Digestive System; | 1967 |
Alcohol, aspirin, and gastrointestinal bleeding.
Topics: Adult; Alcoholic Intoxication; Aspirin; Chromium Isotopes; Feces; Gastrointestinal Hemorrhage; Human | 1968 |
Safprin and gastrointestinal bleeding.
Topics: Adult; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; Melena; Tablets, Enteric-Coated | 1971 |
Studies of gastrointestinal blood loss during ibuprofen therapy.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Benzyl Compounds; Calcium; Chromium Isotopes; Dige | 1970 |
Salicylates in the management of rheumatoid arthritis.
Topics: Aminobenzoates; Arthritis, Rheumatoid; Aspirin; Blood Coagulation; Buffers; Dyspepsia; Gastritis; Ga | 1971 |
947 other studies available for aspirin and Gastrointestinal Hemorrhage
| Article | Year |
|---|---|
Synthesis and analgesic-antiinflammatory activity of some 4- and 5-substituted heteroarylsalicylic acids.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry, Physical; Dogs; Ede | 1978 |
Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis.
Topics: Aspirin; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Female; Gastrointestina | 2021 |
The effect of aspirin in patients with nonvaricose upper gastrointestinal bleeding and risk factors analysis.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hospital Mortality; Humans; Retrospective Studies; Risk Factor | 2022 |
Endoscopy study reveals GI injury after DAPT.
Topics: Aspirin; Endoscopy; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors | 2022 |
Construction of a Model for Predicting the Severity of Diverticular Bleeding in an Elderly Population.
Topics: Aged; Aspirin; Colonoscopy; Diverticular Diseases; Diverticulum, Colon; Gastrointestinal Hemorrhage; | 2022 |
Discontinuing low-dose acetylsalicylic acid after gastrointestinal bleeding is associated with increased mortality.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Proportional Hazards | 2022 |
Synergism interaction between genetic polymorphisms in drug metabolizing enzymes and NSAIDs on upper gastrointestinal haemorrhage: a multicenter case-control study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Gastrointestinal Hemorrhage; | 2022 |
Safety and effectiveness of low-dose aspirin for the prevention of gastrointestinal cancer in adults without atherosclerotic cardiovascular disease: a population-based cohort study.
Topics: Adult; Aspirin; Cardiovascular Diseases; Cohort Studies; Gastrointestinal Hemorrhage; Gastrointestin | 2022 |
Improved Survival for Patients With Acute Upper Gastrointestinal Bleeding While on Antithrombotic Therapy: A Multicenter Prospective Cohort Study.
Topics: Acute Disease; Aspirin; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Prospective Studie | 2023 |
Hospitalisation and associated costs of gastrointestinal bleeding from primary prevention aspirin use in South Australia: a retrospective case series analysis.
Topics: Aged; Aspirin; Australia; Gastrointestinal Hemorrhage; Hospitalization; Humans; Platelet Aggregation | 2022 |
Aspirin improves transplant-free survival after TIPS implantation in patients with refractory ascites: a retrospective multicentre cohort study.
Topics: Ascites; Aspirin; Cohort Studies; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Human | 2022 |
Prior oral proton-pump inhibitor use is associated with reduced severity of aspirin-related upper gastrointestinal bleeding in older people.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; Proton | 2022 |
Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force.
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Colorectal Neoplasms; Female; Gastrointestinal Hemorr | 2022 |
[Idiopathic esophageal submucosal hematoma during antithrombotic therapy for essential thrombocythemia].
Topics: Aged; Aspirin; Chest Pain; Esophageal Diseases; Female; Fibrinolytic Agents; Gastrointestinal Hemorr | 2022 |
VNTR Polymorphism in Intron 4 of the eNOS Gene and the Risk of Gastrointestinal Bleeding: A Case-control Study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Gastrointestinal Hemorrhage; | 2022 |
Strongly increased risk of gastric and duodenal ulcers among new users of low-dose aspirin: results from two large cohorts with new-user design.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Ulcer; Gastrointestinal Hemorrhage; Human | 2022 |
The effect of antithrombotic drug use on delayed bleeding with esophageal endoscopic resection.
Topics: Anticoagulants; Aspirin; Endoscopic Mucosal Resection; Fibrinolytic Agents; Gastrointestinal Hemorrh | 2022 |
Development and Validation of a Novel 1-year Mortality Risk Score That Includes the Use of Antithrombotic in Patients With Overt Gastrointestinal Bleeding.
Topics: Aspirin; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Retrospective Studies; Risk Asses | 2023 |
Effectiveness and Safety of Clopidogrel vs Aspirin in Elderly Patients With Ischemic Stroke.
Topics: Aged; Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrh | 2022 |
Cost-Effectiveness of Vonoprazan Compared With Proton Pump Inhibitors in Patients Taking Low-Dose Aspirin for Secondary Prevention of Cardiovascular Events in Japan.
Topics: Aged; Aspirin; Cardiovascular Diseases; Cost-Benefit Analysis; Esomeprazole; Gastrointestinal Hemorr | 2023 |
Prescribing aspirin to older people - where is the line between cardiovascular benefit and upper gastrointestinal bleeding risk?
Topics: Aged; Aspirin; Gastrointestinal Hemorrhage; Heart; Humans; Platelet Aggregation Inhibitors | 2022 |
The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS) study.
Topics: Aspirin; Gastrointestinal Hemorrhage; Glycated Hemoglobin; Humans; Ischemic Stroke; Platelet Aggrega | 2022 |
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding.
Topics: Aftercare; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; H | 2023 |
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding.
Topics: Aftercare; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; H | 2023 |
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding.
Topics: Aftercare; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; H | 2023 |
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding.
Topics: Aftercare; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; H | 2023 |
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding.
Topics: Aftercare; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; H | 2023 |
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding.
Topics: Aftercare; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; H | 2023 |
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding.
Topics: Aftercare; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; H | 2023 |
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding.
Topics: Aftercare; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; H | 2023 |
Deprescription of aspirin for primary prevention is uncommon at discharge in hospitalised patients with gastrointestinal bleeding.
Topics: Aftercare; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; H | 2023 |
Association between perioperative management of antiplatelet agents and risk of post-endoscopic submucosal dissection bleeding in early gastric cancer: analysis of a nationwide multicenter study.
Topics: Aspirin; Cilostazol; Endoscopic Mucosal Resection; Gastric Mucosa; Gastrointestinal Hemorrhage; Gast | 2023 |
The role of
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Case-Control Studies; Cytochrome P | 2023 |
Aspirin deprescribing in primary prevention of cardiovascular disease: a prospective risk-benefit approach.
Topics: Aspirin; Cardiovascular Diseases; Deprescriptions; Gastrointestinal Hemorrhage; Humans; Primary Prev | 2023 |
Letter: factors influencing discontinuation of aspirin in patients after gastrointestinal bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 2023 |
Letter: factors influencing discontinuation of aspirin in patients after gastrointestinal bleeding - authors' reply.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 2023 |
Use of Antidepressants and the Risk of Upper Gastrointestinal Tract Bleeding: A Case-control Study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Aspirin; Case-Control Studies; Gastr | 2023 |
Association between eupatilin and reduction in small bowel bleeding in aspirin users and aspirin plus acid suppressant users.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Flavonoids; Gastrointestinal Hemorrhage; Humans; P | 2023 |
Risk factors for gastrointestinal bleeding in patients with cerebral infarction after dual antiplatelet therapy.
Topics: Aspirin; Cerebral Infarction; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; H | 2023 |
Long-term effectiveness and safety of cilostazol versus clopidogrel in secondary prevention of noncardioembolic ischemic stroke.
Topics: Aspirin; Cilostazol; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Hemorrhagi | 2023 |
Comparison of Ticagrelor Monotherapy and Ticagrelor Plus Aspirin Among Patients With Acute Coronary Syndrome Combined With High-Risk of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Retrospective Cohort Study.
Topics: Acute Coronary Syndrome; Aspirin; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Is | 2023 |
Trends in Upper Gastrointestinal Bleeding in Patients on Primary Prevention Aspirin: A Nationwide Emergency Department Sample Analysis, 2016-2020.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Emergency Service, | 2023 |
Aspirin is associated with a reduced incidence of liver disease in men.
Topics: Aspirin; Cohort Studies; Fatty Liver; Female; Gastrointestinal Hemorrhage; Humans; Incidence; Liver | 2023 |
Aspirin better than clopidogrel on major adverse cardiovascular events reduction after ischemic stroke: A retrospective nationwide cohort study.
Topics: Aged; Aspirin; Brain Ischemia; Cardiovascular Diseases; Cerebral Hemorrhage; Clopidogrel; Female; Ga | 2019 |
A model to predict the risk of aspirin/non-steroidal anti-inflammatory drugs-related upper gastrointestinal bleeding for the individual patient.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Fem | 2020 |
Acute gastrointestinal hemorrhage in Kawasaki disease occurring before aspirin therapy.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Diagnosis, Differential; Gas | 2019 |
Impact of Anemia on the Risk of Bleeding Following Percutaneous Coronary Interventions in Patients ≥75 Years of Age.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Anemia; Angina, Unstable; Anticoagulants; Antithro | 2020 |
Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Hepatocellular; Female; Gastroin | 2020 |
A case of rectal ulcers during aspirin therapy in acute Kawasaki disease.
Topics: Aspirin; Child, Preschool; Colitis; Gastrointestinal Hemorrhage; Humans; Male; Mucocutaneous Lymph N | 2020 |
Comparison of Hemorrhagic Risk between Prasugrel and Clopidogrel: a Retrospective Study using Adverse Drug Event Reporting Databases.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clinical Trials, Phase II | 2020 |
Ischemic Versus Bleeding Outcomes After Percutaneous Coronary Interventions in Patients With High Bleeding Risk.
Topics: Aged; Aspirin; Cause of Death; Clopidogrel; Comorbidity; Coronary Artery Disease; Dual Anti-Platelet | 2020 |
Aspirin to prevent gastrointestinal cancer - but recent trial data do not fit.
Topics: Aspirin; Colorectal Neoplasms; Gastrointestinal Hemorrhage; Gastrointestinal Neoplasms; Humans | 2020 |
Cap-fitted identification and endoscopic haemostasis of a tiny vascular colonic lesion under maintained triple antithrombotic therapy.
Topics: Aspirin; Blood Transfusion; Clopidogrel; Colonic Diseases; Colonoscopy; Combined Modality Therapy; D | 2021 |
Risk of lower gastrointestinal bleeding and colorectal neoplasms following initiation of low-dose aspirin: a Danish population-based cohort study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Cohort Studies; Coloni | 2020 |
Major bleeding risk and mortality associated with antiplatelet drugs in real-world clinical practice. A prospective cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cohort Studies; Databases, Factual | 2020 |
Gastrointestinal bleeding risk with rivaroxaban vs aspirin in atrial fibrillation: A multinational study.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Cohort Studies; Gastrointestinal Hemorrhage; Humans; R | 2020 |
Are proton pump inhibitors an effective and safe drug not only in the prophylaxis of gastrointestinal bleeding in antithrombotic treatment?
Topics: Aspirin; Clopidogrel; Drug Interactions; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; P | 2020 |
Value of Coronary Artery Calcium Scanning in Association With the Net Benefit of Aspirin in Primary Prevention of Atherosclerotic Cardiovascular Disease.
Topics: Adult; Aspirin; Atherosclerosis; Cohort Studies; Coronary Artery Disease; Coronary Disease; Eye Hemo | 2021 |
Clinical factors associated with safety and efficacy in patients receiving direct oral anticoagulants for non-valvular atrial fibrillation.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulan | 2020 |
Combining antiplatelet and anticoagulant therapy in cardiovascular disease.
Topics: Aged; Anticoagulants; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Humans; Male; P | 2020 |
Daily aspirin for primary prevention increased risk for major GI bleeding in healthy older adults.
Topics: Aged; Aged, 80 and over; Aspirin; Gastrointestinal Hemorrhage; Humans; Incidence; Primary Prevention | 2021 |
Aspirin Reduces the Incidence of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B Receiving Oral Nucleos(t)ide Analog.
Topics: Adult; Aged; Alanine; Antiviral Agents; Aspirin; Carcinoma, Hepatocellular; Drug Therapy, Combinatio | 2021 |
Combined Use of Aspirin and Statin is Associated With a Decreased Incidence of Hepatocellular Carcinoma.
Topics: Aspirin; Carcinoma, Hepatocellular; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hum | 2022 |
Divergent trends of hospitalizations for upper and lower gastrointestinal bleeding based on population prescriptions of aspirin, proton pump inhibitors and Helicobacter pylori eradication therapy: Trends of upper and lower gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagula | 2021 |
A novel gene associated with small bowel bleeding in patients taking low-dose aspirin.
Topics: Aged; Aspirin; Capsule Endoscopy; Cytochrome P450 Family 4; Female; Gastrointestinal Hemorrhage; Gen | 2021 |
VKORC1-1639 G>A Polymorphism and the Risk of Non-Variceal Upper Gastrointestinal Bleeding.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Cross-Sectional Studie | 2017 |
Cost Effectiveness of Gastroprotection with Proton Pump Inhibitors in Older Low-Dose Acetylsalicylic Acid Users in the Netherlands.
Topics: Aged; Aging; Aspirin; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Gastrointestinal Hemo | 2017 |
Gastric Ulcer Hemorrhage - a Potential Life-Threatening Complication of Intragastric Balloon Treatment of Obesity.
Topics: Adult; Aspirin; Bariatric Surgery; Gastric Balloon; Gastrointestinal Hemorrhage; Helicobacter Infect | 2017 |
The risk of lower gastrointestinal bleeding in low-dose aspirin users.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studi | 2017 |
Effect of Antithrombotic Therapy and Long Endoscopic Submucosal Dissection Procedure Time on Early and Delayed Postoperative Bleeding.
Topics: Aged; Aspirin; Endoscopic Mucosal Resection; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Ga | 2017 |
Editorial: lower gastrointestinal bleeding and low-dose aspirin-authors' reply.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans | 2017 |
Editorial: lower gastrointestinal bleeding and low-dose aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; Platelet Aggr | 2017 |
Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events: a population-based cohort study.
Topics: Age Distribution; Age Factors; Aged; Aged, 80 and over; Aspirin; Cohort Studies; England; Female; Ga | 2017 |
Analysis of risk factors for colonic diverticular bleeding and recurrence.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Ca | 2017 |
Stopping antithrombotic therapy after acute upper gastrointestinal bleeding is associated with reduced survival.
Topics: Aged; Aspirin; Female; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Male; | 2018 |
Lower gastrointestinal bleeding in patients with coronary artery disease on antithrombotics and subsequent mortality risk.
Topics: Aged; Anticoagulants; Aspirin; Cohort Studies; Coronary Artery Disease; Drug Therapy; Female; Fibrin | 2018 |
Severity of Gastrointestinal Bleeding in Patients Treated with Direct-Acting Oral Anticoagulants.
Topics: Administration, Oral; Aged; Anticoagulants; Arteriovenous Malformations; Aspirin; Blood Transfusion; | 2018 |
Should This Patient Receive Aspirin?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
Topics: Anticholesteremic Agents; Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Humans; Hyp | 2017 |
Risk factors for postpolypectomy bleeding in patients receiving anticoagulation or antiplatelet medications.
Topics: Aged; Anticoagulants; Aspirin; Case-Control Studies; Clopidogrel; Colonic Polyps; Colonoscopy; Color | 2018 |
EROSION Study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography-Based Management in Plaque Erosion): A 1-Year Follow-Up Report.
Topics: Acute Coronary Syndrome; Adenosine; Adult; Aspirin; Coronary Angiography; Coronary Artery Disease; C | 2017 |
Etiology of gastrointestinal bleeding in patients on dual antiplatelet therapy.
Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Esophageal and G | 2018 |
Continuous Use of Thienopyridine May Be as Safe as Low-Dose Aspirin in Endoscopic Resection of Gastric Tumors.
Topics: Aged; Aged, 80 and over; Aspirin; Drug Administration Schedule; Endoscopic Mucosal Resection; Female | 2018 |
Ischaemic stroke, haemorrhage, and mortality in older patients with chronic kidney disease newly started on anticoagulation for atrial fibrillation: a population based study from UK primary care.
Topics: Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Cerebral Hemorrhage; England; Fe | 2018 |
Addressing unmet needs for patients with previous upper gastrointestinal bleed requiring concomitant aspirin and non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans | 2017 |
Is proton pump inhibitors' prophylaxis indicated for patients on antiplatelet therapy?
Topics: Aspirin; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet | 2018 |
Risk of gastrointestinal bleeding and benefit from colorectal cancer reduction from long-term use of low-dose aspirin: A retrospective study of 612 509 patients.
Topics: Aged; Aspirin; Cohort Studies; Colorectal Neoplasms; Female; Gastrointestinal Hemorrhage; Humans; In | 2018 |
Incidence of Upper and Lower Gastrointestinal Bleeding in New Users of Low-Dose Aspirin.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Follow-Up | 2019 |
Annual Risk of Major Bleeding Among Persons Without Cardiovascular Disease Not Receiving Antiplatelet Therapy.
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Female; Gastrointestinal Hemorrhage; Hemorrhage; Hosp | 2018 |
A case-control study of the risk of upper gastrointestinal mucosal injuries in patients prescribed concurrent NSAIDs and antithrombotic drugs based on data from the Japanese national claims database of 13 million accumulated patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Case-Control Studies; | 2018 |
Aspirin in Primary Prevention of Myocardial Infarction/Angina and Stroke in Hypertensive Patients.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Cardiovascular Diseases; Cross-Sectional S | 2018 |
Maintenance use of non-steroidal anti-inflammatory drugs and risk of gastrointestinal cancer in a nationwide population-based cohort study in Sweden.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemoprevention; Cohort Studies; Cycl | 2018 |
Epidemiology of non-steroidal anti-inflammatory drugs consumption in Spain. The MCC-Spain study.
Topics: Adult; Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Dise | 2018 |
Risk factors for upper gastrointestinal bleeding among aspirin users: An old issue with new findings from a population-based cohort study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Comorbidity; Cyclooxygenase | 2019 |
Preventing arteriovenous shunt failure in hemodialysis patients: a population-based cohort study.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Arteriovenous Shunt, Surgical; Aspirin; Aspirin, Dip | 2019 |
Association between TNF-α polymorphisms and the risk of upper gastrointestinal bleeding induced by aspirin in patients with coronary heart disease.
Topics: Aged; Alleles; Aspirin; Coronary Disease; Female; Gastrointestinal Hemorrhage; Genotype; Haplotypes; | 2019 |
Effect of Continued Administration of Low-dose Aspirin for Intraoperative Bleeding Control in Gastric Endoscopic Submucosal Dissection.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Case-Control Studies; Endoscopic Muco | 2019 |
Comparative outcomes in patients with ulcer- vs non-ulcer-related acute upper gastrointestinal bleeding in the United Kingdom: a nationwide cohort of 4474 patients.
Topics: Aged; Aged, 80 and over; Aspirin; Cohort Studies; Female; Gastrointestinal Hemorrhage; Hospital Mort | 2019 |
[Acute Suppurative Appendicitis Diagnosed by Acute Lower Gastrointestinal Hemorrhage].
Topics: Acute Disease; Appendectomy; Appendicitis; Aspirin; Colonoscopy; Gastrointestinal Hemorrhage; Humans | 2019 |
Feasibility of gastric endoscopic submucosal dissection with continuous low-dose aspirin for patients receiving dual antiplatelet therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Endoscopic Mucosal Resection; Feasibility Studies; Fe | 2019 |
Aspirin for Primary Prevention Reduces Cardiovascular Events, Increases Bleeding Risk.
Topics: Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Platelet Aggregat | 2019 |
[Drug-induced gastrointestinal bleeding].
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Gastroint | 2019 |
Incidences, temporal trends and risks of hospitalisation for gastrointestinal bleeding in new or chronic low-dose aspirin users after treatment for
Topics: Adult; Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pyl | 2020 |
The aspirin cardiovascular/gastrointestinal risk calculator--a tool to aid clinicians in practice.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Aspirin; Cardiovascular Diseases; Dose-Respo | 2013 |
Gastroprotection in low-dose aspirin users for primary and secondary prevention of ACS: results of a cost-effectiveness analysis including compliance.
Topics: Acute Coronary Syndrome; Aspirin; Cost-Benefit Analysis; Drug Therapy, Combination; Gastrointestinal | 2013 |
Characterisation of non-warfarin-associated bleeding events reported to the Norwegian spontaneous reporting system.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Ag | 2013 |
The use of prophylactic gastroprotective therapy in patients with nonsteroidal anti-inflammatory drug- and aspirin-associated ulcer bleeding: a cross-sectional study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cross- | 2013 |
Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis).
Topics: Acute Kidney Injury; Aspirin; Diagnosis, Differential; Gastrointestinal Hemorrhage; Humans; Male; Mi | 2013 |
Multi-institutional prospective evaluation of bowel quality of life after prostate external beam radiation therapy identifies patient and treatment factors associated with patient-reported outcomes: the PROSTQA experience.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Con | 2013 |
Prophylactic effect of egualen sodium, a stable azulene derivative, on gastrointestinal damage induced by ischemia/reperfusion, double antiplatelet therapy and loxoprofen in rats.
Topics: Animals; Aspirin; Azulenes; Benzoquinones; Clopidogrel; Gastric Mucosa; Gastrointestinal Hemorrhage; | 2013 |
Commentary: improving the use of gastroprotective agents among high-risk NSAID users.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; | 2013 |
Commentary: improving the use of gastroprotective agents among high-risk NSAID users--authors' reply.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; | 2013 |
Primary non-variceal upper gastrointestinal bleeding in NSAID and low-dose aspirin users: development and validation of risk scores for either medication in two large Dutch cohorts.
Topics: Adolescent; Adult; Age Factors; Aged; Anemia; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulant | 2014 |
Use of electronic personal health records to identify patients at risk for aspirin-induced gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Aspirin; Electronic Health Records; Female; Gastrointestinal Hemorrhage; Hu | 2013 |
Letter: the burden of co-morbidity in the population contributes more to upper gastrointestinal bleeding than aspirin.
Topics: Algorithms; Aspirin; Cardiovascular Diseases; Female; Gastrointestinal Hemorrhage; Humans; Male; Pla | 2013 |
Letter: the burden of co-morbidity in the population contributes more to upper gastrointestinal bleeding than aspirin--authors' reply.
Topics: Algorithms; Aspirin; Cardiovascular Diseases; Female; Gastrointestinal Hemorrhage; Humans; Male; Pla | 2013 |
Major bleeding events and risk stratification of antithrombotic agents in hemodialysis: results from the DOPPS.
Topics: Aged; Anticoagulants; Aspirin; Cohort Studies; Female; Fibrinolytic Agents; Gastrointestinal Hemorrh | 2013 |
Proton-pump inhibitors can decrease gastrointestinal bleeding after percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Age Factors; Aged; Alcohol Drinking; Angina, Stable; Aspirin; Case-Control | 2013 |
Comparative effect of clopidogrel and aspirin versus aspirin alone on laboratory parameters: a retrospective, observational, cohort study.
Topics: Aged; Aspirin; Biomarkers; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Female; Gastro | 2013 |
Low-dose acetylsalicylic acid and gastrointestinal ulcers or bleeding--a cohort study of the effects of proton pump inhibitor use patterns.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Dose-Response Relationship, | 2013 |
Alternate-day, low-dose aspirin and cancer risk: long-term observational follow-up of a randomized trial.
Topics: Aged; Aspirin; Breast Neoplasms; Colorectal Neoplasms; Drug Administration Schedule; Female; Follow- | 2013 |
Summaries for patients. The effect of low-dose aspirin on colorectal cancer risk in women.
Topics: Aged; Aspirin; Drug Administration Schedule; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; | 2013 |
Gastrointestinal adverse events after dual antiplatelet therapy: clopidogrel is safer than ticagrelor, but prasugrel data are lacking or inconclusive.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Chemical and Drug Induced Liver Injury; Clinical Trials | 2013 |
Proximal predominance of small bowel injury associated with uncoated low-dose aspirin therapy: a video capsule study in chronic users.
Topics: Aged; Aged, 80 and over; Anemia, Iron-Deficiency; Anti-Inflammatory Agents, Non-Steroidal; Anticoagu | 2013 |
Relationship between continuous use of low-dose enteric-coated aspirin and gastrointestinal injuries in patients with gastrointestinal hemorrhage.
Topics: Aspirin; Case-Control Studies; Duodenal Ulcer; Endoscopy, Gastrointestinal; Female; Gastrointestinal | 2013 |
Cardiovascular and upper gastrointestinal bleeding consequences of low-dose acetylsalicylic acid discontinuation.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Case-Control Studies; Female; Follow-Up S | 2013 |
The postoperative bleeding rate and its risk factors in patients on antithrombotic therapy who undergo gastric endoscopic submucosal dissection.
Topics: Adenoma; Aged; Anti-Ulcer Agents; Anticoagulants; Aspirin; Carcinoma; Case-Control Studies; Clopidog | 2013 |
Endoscopic biopsy on patients taking antiplatelet agents: how much do we follow BSG, ASGE or ESGE guidelines?
Topics: Aspirin; Biopsy; Clopidogrel; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Humans; Phys | 2014 |
Risk factors of gastrointestinal bleeding in clopidogrel users: a nationwide population-based study.
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Cohort Studies; Da | 2013 |
Bleeding-related symptoms in colorectal cancer: a 4-year nationwide population-based study.
Topics: Aged; Aged, 80 and over; Anemia, Iron-Deficiency; Anticoagulants; Aspirin; Colorectal Neoplasms; Fem | 2014 |
Continued use of low-dose aspirin does not increase the risk of bleeding during or after endoscopic submucosal dissection for early gastric cancer.
Topics: Aged; Aged, 80 and over; Aspirin; Dissection; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; G | 2014 |
Atrial fibrillation patients do not benefit from acetylsalicylic acid.
Topics: Aged; Aged, 80 and over; Aspirin; Atrial Fibrillation; Brain Ischemia; Cohort Studies; Female; Gastr | 2014 |
Guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment.
Topics: Aspirin; Contraindications; Endoscopy, Gastrointestinal; Fibrinolytic Agents; Gastrointestinal Hemor | 2014 |
How important is it to keep taking the aspirin?
Topics: Aspirin; Cardiovascular Diseases; Female; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation | 2013 |
Low-dose aspirin and upper gastrointestinal bleeding in primary versus secondary cardiovascular prevention: a population-based, nested case-control study.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Case-Control Studies; Dose-Respons | 2014 |
Predictors of favourable outcome in non-variceal upper gastrointestinal bleeding: implications for early discharge?
Topics: Age Factors; Aged; Aged, 80 and over; Aspirin; Blood Transfusion; Endoscopy, Digestive System; Esoph | 2014 |
Novel single nucleotide polymorphism markers for low dose aspirin-associated small bowel bleeding.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Dose-Response Relationship, Drug; Female; Gastrointestinal | 2013 |
Is enteric aspirin safer than regular aspirin?
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, | 2013 |
[Meckel's diverticulum detected by virtual enteroscopy in a patient with nonsteroidal anti-inflammatory drug-induced enteropathy].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Endoscopy, Gastrointestinal; Female; Gastroi | 2014 |
Incidence and related factors of upper gastrointestinal bleeding in a Chinese population of peripheral arterial disease during a six-year follow-up.
Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; China; Comorbidity; Female; Fibrinoly | 2014 |
Analysis of gastrointestinal prophylaxis in patients receiving dual antiplatelet therapy with aspirin and clopidogrel.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Gastrointestinal H | 2014 |
Safety of discontinuation of anti-coagulation in patients with continuous-flow left ventricular assist devices.
Topics: Adult; Aged; Anticoagulants; Aspirin; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Heart | 2014 |
Difference in risk of gastrointestinal complications between users of enteric-coated and buffered low-dose aspirin.
Topics: Adult; Aged; Aspirin; Buffers; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Pepti | 2014 |
Spontaneous omental bleeding in the setting of dual anti-platelet therapy with ticagrelor.
Topics: Adenosine; Aged; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Male; Myocardial Infarct | 2014 |
Alendronate, a bisphosphonate, increased upper and lower gastrointestinal bleeding: risk factor analysis from a nationwide population-based study.
Topics: Age Factors; Aged; Aged, 80 and over; Alendronate; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 2014 |
Does rebamipide prevent gastric mucosal injury in patients taking aspirin and clopidogrel?
Topics: Alanine; Anti-Ulcer Agents; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Male; Platele | 2014 |
Colonic diverticular hemorrhage associated with the use of nonsteroidal anti-inflammatory drugs, low-dose aspirin, antiplatelet drugs, and dual therapy.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2014 |
Fatal bleedings with prasugrel as part of triple antithrombotic therapy.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Arteriovenous Malformations; Aspirin; Drug The | 2014 |
Successful treatment of bleeding large duodenal gastrointestinal stromal tumour in a patient under dual antiplatelet therapy after recent drug-eluting coronary stent implantation.
Topics: Aged; Aspirin; Benzamides; Chemotherapy, Adjuvant; Clopidogrel; Coronary Stenosis; Drug-Eluting Sten | 2014 |
Myocardial infarction and gastro-intestinal bleeding risks associated with aspirin use among elderly individuals with type 2 diabetes.
Topics: Aged; Aged, 80 and over; Aspirin; Case-Control Studies; Cohort Studies; Databases, Factual; Diabetes | 2014 |
Similarities and differences in the clinical features between cardia varices and esophageal varices.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardia; Esophageal | 2014 |
Proton-pump inhibitors in patients requiring antiplatelet therapy: new FDA labeling.
Topics: Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cytochrome P-450 CYP2C19; Drug Antagonism; Drug | 2014 |
Risk of upper gastrointestinal bleeding from different drug combinations.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Cyclooxyg | 2014 |
Recurrence and mortality among patients hospitalized for acute lower gastrointestinal bleeding.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Fema | 2015 |
Lower GI bleeding risk of nonsteroidal anti-inflammatory drugs and antiplatelet drug use alone and the effect of combined therapy.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Clopidogrel; Colonic D | 2014 |
Patterns in the use of low-dose acetylsalicylic acid and other therapies following upper gastrointestinal bleeding.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cardiovascular Diseases; Cohort Studies; Da | 2014 |
NSAID-associated gastrointestinal bleeding: assessing the role of concomitant medications.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Gastrointestinal Hemorr | 2014 |
[Clinical impact of dual antiplatelet therapy on peptic ulcer disease].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Angiography; Coronary | 2014 |
Effect of low-dose proton pump inhibitor on preventing upper gastrointestinal bleeding in chronic kidney disease patients receiving aspirin.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Dialysis; Female; Follow-Up Studies; Gastrointestinal Hemor | 2015 |
Small-bowel mucosal injuries in low-dose aspirin users with obscure gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capsule Endoscopy; Case-C | 2014 |
[Gastrointestinal bleeding, NSAIDs, aspirin and anticoagulants].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Gastrointestinal Hemorrhage; Human | 2014 |
Researchers ponder aspirin's potential in preventing cancer.
Topics: Aged; Aspirin; Gastrointestinal Hemorrhage; Humans; Middle Aged; Neoplasms; Primary Prevention; Risk | 2014 |
Low-Dose Aspirin and Non-steroidal Anti-inflammatory Drugs Increase the Risk of Bleeding in Patients with Gastroduodenal Ulcer.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Case-Cont | 2015 |
Rebleeding after initial endoscopic hemostasis in peptic ulcer disease.
Topics: Antithrombins; Aspirin; Female; Gastrointestinal Hemorrhage; Hemorrhage; Hemostasis, Endoscopic; Hum | 2014 |
[An analysis of clinical characteristics and risk factors for ulceration in ischemic colitis].
Topics: Aged; Aspirin; Colitis, Ischemic; Constipation; Female; Gastrointestinal Hemorrhage; Hospitalization | 2014 |
Nonsteroidal anti-inflammatory and antiplatelet drugs and risk of GI bleeding: don't forget the colon.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; | 2014 |
Aspirin use in women for primary prevention.
Topics: Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Myocardial Infarction; Neoplasms; Platelet Agg | 2015 |
Cons outweigh pros of preventive aspirin in women, study finds.
Topics: Aspirin; Cardiovascular Diseases; Female; Gastrointestinal Hemorrhage; Humans; Neoplasms; Platelet A | 2014 |
Patterns of Antiplatelet Therapy in Patients Who Have Experienced an Acute Coronary Event: A Descriptive Study in UK Primary Care.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cohort Studies; Female; Foll | 2015 |
Assessment of risk of late rectal bleeding for patients with prostate cancer started on anticoagulation before or after radiation treatment.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; | 2014 |
Effect of rebamipide on gastric bleeding and ulcerogenic responses induced by aspirin plus clopidogrel under stimulation of acid secretion in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Disease Models, Animal; Gastric Acid; Gas | 2014 |
The role of the cardiologist in the primary prevention of cardiovascular disease with aspirin.
Topics: Aspirin; Cardiovascular Diseases; Female; Gastrointestinal Hemorrhage; Humans; Male; Primary Prevent | 2015 |
Risk of bleeding after endoscopic submucosal dissection for colorectal tumors in patients with continued use of low-dose aspirin.
Topics: Aged; Aspirin; Colonoscopy; Colorectal Neoplasms; Dissection; Dose-Response Relationship, Drug; Fema | 2015 |
Effect of proton-pump inhibitors on the risk of lower gastrointestinal bleeding associated with NSAIDs, aspirin, clopidogrel, and warfarin.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Case-Control Studies; | 2015 |
Aspirin Has a Protective Effect Against Adverse Outcomes in Patients with Nonvariceal Upper Gastrointestinal Bleeding.
Topics: Adult; Aged; Aging; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Female; Fibrinolytic Agents | 2015 |
Time-trends in the prescribing of gastroprotective agents to primary care patients initiating low-dose aspirin or non-steroidal anti-inflammatory drugs: a population-based cohort study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Databases | 2015 |
Account should also have been taken of the harm versus benefit of aspirin use.
Topics: Aged; Aged, 80 and over; Aspirin; Atrial Fibrillation; Gastrointestinal Hemorrhage; Humans; Platelet | 2015 |
Analysis of the Interaction between Clopidogrel, Aspirin, and Proton Pump Inhibitors Using the FDA Adverse Event Reporting System Database.
Topics: Adverse Drug Reaction Reporting Systems; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Comb | 2015 |
Cost-Effectiveness of Proton Pump Inhibitor Co-Therapy in Patients Taking Aspirin for Secondary Prevention of Ischemic Stroke.
Topics: Aspirin; Cost-Benefit Analysis; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Inci | 2015 |
[Kasabach-Merritt phenomenon (KMP) exacerbated by platelet transfusions].
Topics: Aspirin; Axilla; Combined Modality Therapy; Compression Bandages; Disease Progression; Disseminated | 2015 |
Proton pump inhibitors are associated with lower gastrointestinal tract bleeding in low-dose aspirin users with ischaemic heart disease.
Topics: Aged; Aspirin; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Histamine H2 Antagoni | 2015 |
Epidemiology of Upper Gastrointestinal Damage Associated with Low-Dose Aspirin.
Topics: Age Factors; Aged; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Gastrointes | 2015 |
Formalin therapy for hemorrhagic radiation proctitis.
Topics: Administration, Rectal; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Argon; Asp | 2015 |
Risk factors for adverse in-hospital outcomes in acute colonic diverticular hemorrhage.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Transfusion; Colonoscopy; Diverticulum | 2015 |
Predictors of hospital mortality and serious complications in patients admitted with excessive warfarin anticoagulation.
Topics: Anticoagulants; Aspirin; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Hospital Mo | 2016 |
Accurate triage of lower gastrointestinal bleed (LGIB) - A cohort study.
Topics: Acute Disease; Adult; Aged; Aspirin; Cohort Studies; Comorbidity; Emergency Service, Hospital; Femal | 2016 |
Efficacy of Contrast-enhanced Computed Tomography for the Treatment Strategy of Colonic Diverticular Bleeding.
Topics: Aged; Aspirin; Colonic Diseases; Colonoscopy; Contrast Media; Diverticulum, Colon; Female; Gastroint | 2015 |
A long-term risk-benefit analysis of low-dose aspirin in primary prevention.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Databases, Factual; Female; Gastro | 2016 |
Successful Management of Recurrent Colon Ulcer in Hemodialysis Patient after Conversion to Peritoneal Dialysis.
Topics: Aspirin; Colon; Colonic Diseases; Colonoscopy; Drug Therapy, Combination; Gastrointestinal Hemorrhag | 2015 |
Proton pump inhibitors, histamine-2 receptor antagonists, gastroprotection and lower gastrointestinal tract bleeding in low-dose aspirin users.
Topics: Aspirin; Female; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Male; Myocardial Isc | 2016 |
[A rare differential diagnosis of acute lower gastrointestinal bleeding: Small-bowel diverticulosis].
Topics: Accidental Falls; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents, Non-S | 2015 |
Acute Retroperitoneal Hematoma After Psoas Catheter Placement in a Patient with Myeloproliferative Thrombocytosis and Aspirin Therapy.
Topics: Aged, 80 and over; Aspirin; Catheters; Gastrointestinal Hemorrhage; Hematoma; Humans; Male; Myelopro | 2016 |
Management of acute perioperative myocardial infarction: a case report of concomitant acute myocardial infarction and tumor bleeding in the transverse colon.
Topics: Aged; Aspirin; Colon, Transverse; Colonic Neoplasms; Colonoscopy; Coronary Angiography; Disease Mana | 2016 |
Acute Middle Gastrointestinal Bleeding Risk Associated with NSAIDs, Antithrombotic Drugs, and PPIs: A Multicenter Case-Control Study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Ca | 2016 |
Decision-making in an era of cancer prevention via aspirin: New Zealand needs updated guidelines and risk calculators.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clinical Decision-M | 2016 |
[Risk factors for re-bleeding events in obscure gastrointestinal bleeding patients with negative findings in capsule endoscopy].
Topics: Aspirin; Capsule Endoscopy; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Laparoscopy; Ris | 2016 |
Proton pump inhibitors and other disease-based factors in the recurrence of adverse cardiovascular events following percutaneous coronary angiography: A long-term cohort.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Drug Combinations; Female; Foll | 2016 |
Aspirin for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: A Decision Analysis for the U.S. Preventive Services Task Force.
Topics: Adult; Aged; Anticarcinogenic Agents; Aspirin; Cardiovascular Diseases; Colorectal Neoplasms; Decisi | 2016 |
Aspirin Use for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: Recommendations From the U.S. Preventive Services Task Force.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Aspirin; Cardiovascular Diseases; Cerebral Hemorrha | 2016 |
Risks of Bleeding Recurrence and Cardiovascular Events With Continued Aspirin Use After Lower Gastrointestinal Hemorrhage.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Female; Gastrointes | 2016 |
Factors predicting adverse events associated with therapeutic colonoscopy for colorectal neoplasia: a retrospective nationwide study in Japan.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Ce | 2016 |
[The incidence, clinical characteristics and risk factors of upper gastrointestinal bleeding in patients taking dual antiplatelet therapy after percutaneous coronary intervention in south China].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; China; Clopidogrel; Coronary Artery Disease; Femal | 2016 |
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont | 2016 |
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont | 2016 |
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont | 2016 |
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont | 2016 |
Effects of low-dose aspirin in subjects with dyslipidemia.
Topics: Adult; Aspirin; C-Reactive Protein; Cholesterol, LDL; Convalescence; Coronary Angiography; Coronary | 2016 |
GI-Safer Aspirin: Sometimes Sugar Coating Helps.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; Platelet Aggr | 2016 |
Concurrent Lower Gastrointestinal Bleeding Risk and Myocardial Ischemic Risk: Resume Aspirin or Not?
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Ischemia; Platelet Aggregation Inhibitors; Risk | 2016 |
Review: Aspirin for CVD primary prevention increases gastrointestinal bleeding and hemorrhagic stroke.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Intracranial Hemorrhages; Platelet Aggregation Inhibit | 2016 |
Antiplatelet Therapy is Associated with a Better Prognosis for Patients with Hepatitis B Virus-Related Hepatocellular Carcinoma after Liver Resection.
Topics: Adult; Aged; Aspirin; Carcinoma, Hepatocellular; Clopidogrel; Disease-Free Survival; Female; Gastroi | 2016 |
High Risk of Gastrointestinal Bleeding on Dual Antiplatelet Treatment.
Topics: Aspirin; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibi | 2016 |
Reply: High Risk of Gastrointestinal Bleeding on Dual Antiplatelet Treatment.
Topics: Aspirin; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibi | 2016 |
Risk of bleeding after hospitalization for a serious coronary event: a retrospective cohort study with nested case-control analyses.
Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Clopidogrel; Confidence Intervals; Coronary A | 2016 |
Safety and efficacy of new oral anticoagulants and low-molecular-weight heparins compared with aspirin in patients undergoing total knee and hip replacements.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Arthroplasty, Replacement, Hip; Arthr | 2016 |
Compliance with USPSTF recommendations on aspirin for prevention of cardiovascular disease in men.
Topics: Aged; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Gastrointestinal Hemorrhage; Guidel | 2016 |
[Dose-response of aspirin on platelet function in very elderly patients].
Topics: Aged, 80 and over; Arachidonic Acid; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Fem | 2016 |
A Prospective Study of Alcohol Consumption and Smoking and the Risk of Major Gastrointestinal Bleeding in Men.
Topics: Alcohol Drinking; Alcoholic Beverages; Aspirin; Beer; Ethanol; Follow-Up Studies; Gastrointestinal H | 2016 |
Advances in gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; | 2016 |
Mortality in patients who discontinue low-dose acetylsalicylic acid therapy after upper gastrointestinal bleeding.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort S | 2017 |
Aspirin Use for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer.
Topics: Age Factors; Aspirin; Cardiovascular Diseases; Clinical Decision-Making; Colorectal Neoplasms; Femal | 2016 |
Nonsteroidal anti-inflammatory drugs-induced small bowel enteropathy and obscure gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Capsule Endoscopy; Case-Control Studies | 2018 |
Protons pump inhibitor treatment and lower gastrointestinal bleeding: Balancing risks and benefits.
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Gastrointestina | 2016 |
RE: Risks of Bleeding Recurrence and Cardiovascular Events With Continued Aspirin Use After Lower Gastrointestinal Hemorrhage.
Topics: Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibito | 2017 |
Another Go Around for Aspirin: The Gut Is the Heart of the Matter this Time.
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Colonic Neopl | 2017 |
Risk of major bleeding and stroke associated with the use of vitamin K antagonists, nonvitamin K antagonist oral anticoagulants and aspirin in patients with atrial fibrillation: a cohort study.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; | 2017 |
Upper gastrointestinal bleeding in patients with aspirin and clopidogrel co-therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Female; | 2008 |
The coadministration of paroxetine and low-dose aspirin synergistically enhances gastric ulcerogenic risk in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Dose-Response Relationship, | 2008 |
Consistent aspirin use associated with improved arteriovenous fistula survival among incident hemodialysis patients in the dialysis outcomes and practice patterns study.
Topics: Aged; Arteriovenous Shunt, Surgical; Aspirin; Australia; Europe; Female; Gastrointestinal Hemorrhage | 2008 |
Proton pump inhibitors reduce the long-term risk of recurrent upper gastrointestinal bleeding: an observational study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; | 2008 |
Cost-effectiveness of proton pump inhibitor cotherapy in patients taking long-term, low-dose aspirin for secondary cardiovascular prevention.
Topics: Aged; Aspirin; Cardiovascular Diseases; Coronary Disease; Cost-Benefit Analysis; Dose-Response Relat | 2008 |
Age threshold for vascular prophylaxis by aspirin in patients without diabetes.
Topics: Adult; Age Factors; Aged; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Female; Gastroi | 2008 |
Management and outcome of peptic ulcers or erosions in patients receiving a combination of aspirin plus clopidogrel.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Coronary Disease; Female; Gastr | 2008 |
The influence of polymorphisms of VKORC1 and CYP2C9 on major gastrointestinal bleeding risk in anticoagulated patients.
Topics: Acenocoumarol; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents | 2008 |
Giant small-bowel GI stromal tumor: aspirin provocation to endoscopically unmask site of obscure overt GI bleeding.
Topics: Adult; Aspirin; Capsule Endoscopy; Endoscopy, Gastrointestinal; Gastrointestinal Hemorrhage; Gastroi | 2008 |
Colonic carcinoma unmasked by dual antiplatelet therapy.
Topics: Aspirin; Clopidogrel; Colonic Neoplasms; Female; Gastrointestinal Hemorrhage; Humans; Incidental Fin | 2008 |
ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Combina | 2008 |
Ethical considerations in relation to aspirin prophylaxis.
Topics: Age Factors; Aspirin; Cardiovascular Diseases; Dose-Response Relationship, Drug; Ethics, Medical; Ga | 2008 |
Bleeding risks with combination of oral anticoagulation plus antiplatelet therapy: is clopidogrel any safer than aspirin when combined with warfarin?
Topics: Administration, Oral; Anticoagulants; Aspirin; Blood Coagulation; Clopidogrel; Coumarins; Dipyridamo | 2008 |
Effect of oral antiplatelet agents on major bleeding in users of coumarins.
Topics: Acenocoumarol; Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Coagula | 2008 |
Add an acid blocker to prevent aspirin therapy complications. Aspirin can increase your risk of upper GI bleeding, but medication can help.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Acid; Gastrointestinal Hemorrhage; Humans; | 2008 |
Usefulness of anti-ulcer drugs for the prevention and treatment of peptic ulcers induced by low doses of aspirin.
Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Aspirin; Female; Gastric Mucosa; Gastrointestinal | 2009 |
Aspirin for the prevention of cardiovascular disease: U.S. Preventive Services Task Force recommendation statement.
Topics: Age Factors; Aged; Aspirin; Brain Ischemia; Cardiovascular Diseases; Cost of Illness; Female; Gastro | 2009 |
Sensitivity, but not specificity, of a quantitative immunochemical fecal occult blood test for neoplasia is slightly increased by the use of low-dose aspirin, NSAIDs, and anticoagulants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Colonic Polyps; Colonoscopy; Color | 2009 |
Sensitivity, but not specificity, of a quantitative immunochemical fecal occult blood test for neoplasia is slightly increased by the use of low-dose aspirin, NSAIDs, and anticoagulants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Colonic Polyps; Colonoscopy; Color | 2009 |
Sensitivity, but not specificity, of a quantitative immunochemical fecal occult blood test for neoplasia is slightly increased by the use of low-dose aspirin, NSAIDs, and anticoagulants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Colonic Polyps; Colonoscopy; Color | 2009 |
Sensitivity, but not specificity, of a quantitative immunochemical fecal occult blood test for neoplasia is slightly increased by the use of low-dose aspirin, NSAIDs, and anticoagulants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Colonic Polyps; Colonoscopy; Color | 2009 |
Do statins protect against upper gastrointestinal bleeding?
Topics: Aged; Aged, 80 and over; Aspirin; Case-Control Studies; Denmark; Dose-Response Relationship, Drug; D | 2009 |
Proton pump inhibitors and clopidogrel - hazardous drug interaction or hazardous interpretation of data?
Topics: Aspirin; Clopidogrel; Cytochrome P-450 Enzyme System; Data Interpretation, Statistical; Drug Interac | 2009 |
Characteristics of small bowel injury in symptomatic chronic low-dose aspirin users: the experience of two medical centers in capsule endoscopy.
Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ca | 2009 |
Decreasing incidence of peptic ulcer complications after the introduction of the proton pump inhibitors, a study of the Swedish population from 1974-2002.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Dose-Response Relationshi | 2009 |
[Aspirin and gastrointestinal bleeding: the problem we confront with].
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 2009 |
[The use of recombinant activated factor VII in the treatment of gastrointestinal bleeding following acetylsalicylic acid therapy in a surgical patient].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Factor VIIa; Female; Gastrointestinal Hemor | 2008 |
Aspirin for heart attack, stroke prevention. When benefits outweigh risks: four new studies help clarify who should--and who shouldn't--take the drug.
Topics: Aspirin; Clopidogrel; Contraindications; Drug Interactions; Drug Therapy, Combination; Female; Gastr | 2009 |
Gastroprotective strategy in aspirin users.
Topics: Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Hum | 2009 |
Use of gastroprotective drugs in patients receiving low-dose aspirin.
Topics: Adult; Aged; Aged, 80 and over; Antacids; Aspirin; Female; Gastrointestinal Hemorrhage; Histamine H2 | 2009 |
Co-prescription of gastro-protectants in hospitalized patients: an analysis of what we do and what we think we do.
Topics: Aged; Aged, 80 and over; Aspirin; Attitude of Health Personnel; Clopidogrel; Data Collection; Female | 2010 |
Effects of gastric medicines on gastroduodenal injury in patients with stable angina during antiplatelet therapy.
Topics: Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Female; Follow-Up Studies; Gastric M | 2009 |
Aspirin or paracetamol - what's good for you?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical | 2009 |
Common drugs can harm elderly patients.
Topics: Aged; Anticoagulants; Aspirin; Cardiovascular Diseases; Cerebral Hemorrhage; Drug Therapy, Combinati | 2009 |
Aspirin increases mortality in diabetic patients without cardiovascular disease: a Swedish record linkage study.
Topics: Age Factors; Aged; Aspirin; Cardiovascular Diseases; Diabetes Complications; Female; Gastrointestina | 2009 |
Predictive value of post-treatment platelet reactivity for occurrence of post-discharge bleeding after non-ST elevation acute coronary syndrome. Shifting from antiplatelet resistance to bleeding risk assessment?
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Biomarkers; Cell Ad | 2009 |
Upper gastrointestinal hemorrhage: have new therapeutics made a difference?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chi-Square Distribution; Cyclooxygenase 2 Inhibito | 2009 |
Upper gastrointestinal bleeding in patients receiving dual antiplatelet therapy after coronary stenting.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Aspirin; Cilostazol; Clopidogrel; Co | 2009 |
Myocardial infarction, peptic ulcer and acetylsalicylic acid: of good and evil.
Topics: Aspirin; Endoscopy, Digestive System; Gastroenterology; Gastrointestinal Hemorrhage; Humans; Myocard | 2009 |
Acetylsalicylic acid use in patients with acute myocardial infarction and peptic ulcer bleeding.
Topics: Aged; Aspirin; Blood Transfusion; Endoscopy, Digestive System; Female; Gastrointestinal Hemorrhage; | 2009 |
A comparison of aspirin and clopidogrel with or without proton pump inhibitors for the secondary prevention of cardiovascular events in patients at high risk for gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Databases, Factual; Drug Cos | 2009 |
Etiology of upper gastrointestinal bleeding in young children.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Endoscopy, Gastrointestinal; Female; Gastrointesti | 2009 |
Massive GI bleeding due to accidental ASA inhalation.
Topics: Administration, Inhalation; Adult; Animal Feed; Animals; Aspirin; Gastrointestinal Hemorrhage; Human | 2010 |
Clinical features of gastroduodenal ulcer in Japanese patients taking low-dose aspirin.
Topics: Aged; Aged, 80 and over; Asian People; Aspirin; Endoscopy, Gastrointestinal; Female; Gastrointestina | 2010 |
Aspirin withdrawal in acute peptic ulcer bleeding: are we harming patients?
Topics: Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Gastrointestinal Hemorrhage; Humans; Pe | 2010 |
Summaries for patients. Benefits and risks of continuing aspirin in patients with peptic ulcer bleeding.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Ster | 2010 |
Aspirin, iron loss, and age-related macular degeneration.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Iron Overload; Macular Degeneration | 2010 |
Summaries for patients. Management of nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Blood Transfusion; | 2010 |
Endoscopic application of hemostatic thrombin-gelatin matrix (FloSeal) in anticoagulated pigs.
Topics: Animals; Anticoagulants; Aspirin; Blood Coagulation Disorders; Disease Models, Animal; Endoscopy; Ga | 2010 |
Fecal occult blood test in patients on low-dose aspirin, warfarin, clopidogrel, or non-steroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Colonic Neoplas | 2010 |
Relation of proton pump inhibitor use after percutaneous coronary intervention with drug-eluting stents to outcomes.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Drug-Eluting Stents; Female; Gastrointes | 2010 |
Defining patients at high risk for gastrointestinal hemorrhage after drug-eluting stent placement: a cost utility analysis.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Cohort Studies; Coronary Stenosis; Cost-Benefit Analysis; D | 2010 |
Increased incidence of gastrointestinal bleeding following implantation of the HeartMate II LVAD.
Topics: Anticoagulants; Aspirin; Dipyridamole; Female; Gastrointestinal Hemorrhage; Heart Ventricles; Heart- | 2010 |
Management of antiplatelet treatment in patients undergoing endoscopic procedures.
Topics: Aspirin; Endoscopy; Evidence-Based Medicine; Gastrointestinal Hemorrhage; Humans; Platelet Aggregati | 2010 |
An aspirin a day?
Topics: Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Humans; Risk Factors | 2010 |
Probing the occult: testing for blood in the stools.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Colonic Neoplasms; Co | 2010 |
Role of melatonin in mucosal gastroprotection against aspirin-induced gastric lesions in humans.
Topics: Adult; Aspirin; Dinoprostone; Gastric Mucosa; Gastrins; Gastrointestinal Hemorrhage; Humans; Male; M | 2010 |
Low prevalence of idiopathic peptic ulcer disease: an Italian endoscopic survey.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biops | 2010 |
CYP2C9*3 Loss-of-Function Allele Is Associated With Acute Upper Gastrointestinal Bleeding Related to the Use of NSAIDs Other Than Aspirin.
Topics: Aged; Aged, 80 and over; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aryl H | 2010 |
PPI use in patients commenced on clopidogrel: a retrospective cross-sectional evaluation.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cohort Studies; Cross-Sectional Studies; Drug | 2010 |
Antiplatelet therapy in the treatment of Takayasu arteritis.
Topics: Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Humans; Ischemia; Platelet Aggregatio | 2010 |
Clinical features and risk factors for upper gastrointestinal bleeding in children: a case-crossover study.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Confidence Intervals; Cross-Ove | 2010 |
Withdrawal of clopidogrel in active gastric bleeding.
Topics: Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; Gastrointestinal Hemorrhag | 2010 |
Aspirin use in elderly women receiving medication therapy management services.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Comorbidity; Contraindications; Diabetes | 2010 |
Underutilization of gastroprotection for at-risk patients undergoing percutaneous coronary intervention: Spain compared with the United States.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Surgical P | 2010 |
Impact of aspirin, NSAIDs, warfarin, corticosteroids and SSRIs on the site and outcome of non-variceal upper and lower gastrointestinal bleeding.
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 2010 |
Double jeopardy: pyogenic liver abscess and massive secondary rectal haemorrhage after rubber band ligation of haemorrhoids.
Topics: Aspirin; Diabetes Complications; Enterobacter aerogenes; Enterobacteriaceae Infections; Gastrointest | 2011 |
Potential economic impact of increasing low dose aspirin usage on CVD in the US.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Chemoprevention; Cost | 2010 |
Cardiovascular and gastrointestinal events of three antiplatelet therapies: clopidogrel, clopidogrel plus proton-pump inhibitors, and aspirin plus proton-pump inhibitors in patients with previous gastrointestinal bleeding.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Dru | 2011 |
Renin-angiotensin system associated with risk of upper GI mucosal injury induced by low dose aspirin: renin angiotensin system genes' polymorphism.
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Aspirin; Case-Control Studies; Dose-Response Relationshi | 2011 |
[Does dual antiplatelet therapy always require gastroprotection? Tailored medical therapy should prevail over the generalized prescription of proton pump inhibitors in patients on dual antiplatelet therapy].
Topics: Acute Coronary Syndrome; Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Elect | 2010 |
[Does dual antiplatelet therapy always require gastroprotection? Gastroprotection with proton pump inhibitors is advisable for all patients who need dual antiplatelet therapy].
Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cyclo | 2010 |
Combination of low-dose aspirin and thienopyridine exacerbates small bowel injury.
Topics: Aged; Aged, 80 and over; Aspirin; Capsule Endoscopy; Clopidogrel; Drug Therapy, Combination; Female; | 2011 |
Low-dose aspirin use and performance of immunochemical fecal occult blood tests.
Topics: Aged; Aspirin; Colorectal Neoplasms; False Positive Reactions; Female; Gastrointestinal Hemorrhage; | 2010 |
[Efficacy and safety of concomitant use of rabeprazole during dual-antiplatelet therapy with clopidogrel and aspirin after drug-eluting stent implantation: a retrospective cohort study].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; | 2010 |
Negative capsule endoscopy for obscure gastrointestinal bleeding is closely associated with the use of low-dose aspirin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2011 |
The changing face of hospitalisation due to gastrointestinal bleeding and perforation.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointestinal | 2011 |
A prospective study of aspirin use and the risk of gastrointestinal bleeding in men.
Topics: Aged; Aspirin; Blood Transfusion; Cohort Studies; Gastrointestinal Hemorrhage; Hemorrhage; Humans; M | 2010 |
Spontaneous intramural duodenal haematoma with transient biliary obstruction and acute cholecystitis.
Topics: Aspirin; Cholecystitis, Acute; Cholestasis, Extrahepatic; Duodenal Diseases; Female; Gastrointestina | 2010 |
Antiplatelet agents do not impact the hospital course in patients with gastrointestinal bleeding.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Cohor | 2011 |
Use of aspirin or nonsteroidal anti-inflammatory drugs increases risk for diverticulitis and diverticular bleeding.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diverticulitis; Follow-Up Studies; Ga | 2011 |
Cost-utility of aspirin and proton pump inhibitors for primary prevention.
Topics: Aged; Aspirin; Coronary Disease; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Gastr | 2011 |
Risk of upper gastrointestinal bleeding with low-dose acetylsalicylic acid alone and in combination with clopidogrel and other medications.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; An | 2011 |
Concomitant use of SSRIs, NSAIDs/aspirin and gastroprotective drugs among residents of long-term care facilities: a medical record review.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Interactions; Female | 2011 |
Performance of immunochemical fecal occult blood tests among users of low-dose aspirin.
Topics: Aspirin; Cardiovascular Diseases; Colorectal Neoplasms; Gastrointestinal Hemorrhage; Humans; Occult | 2011 |
Optimal timing of anticoagulation pre- and post-colonoscopy with polypectomy.
Topics: Anticoagulants; Aspirin; Clopidogrel; Colonic Polyps; Colonoscopy; Female; Gastrointestinal Hemorrha | 2011 |
Acute upper gastrointestinal hemorrhage in an elderly woman taking aspirin and clopidogrel.
Topics: Aged; Aspirin; Clopidogrel; Female; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibi | 2011 |
Incidence of gastrointestinal bleeding in patients with cardiovascular disease: buffered aspirin versus enteric-coated aspirin.
Topics: Aged; Aged, 80 and over; Aspirin; Buffers; Cardiovascular Diseases; Female; Gastrointestinal Hemorrh | 2011 |
[Does combination therapy of aspirin plus antiplatelet therapy increase the risk of upper gastrointestinal hemorrhage?].
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Endos | 2011 |
[The effect of aspirin alone or aspirin plus additional antiplatelets therapy on upper gastrointestinal hemorrhage].
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; | 2011 |
Long-term use of aspirin and the risk of gastrointestinal bleeding.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Drug Admin | 2011 |
Gastrointestinal bleeding and outcomes after percutaneous coronary intervention for ST-segment elevation myocardial infarction.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Clopidogrel; Female; Gastrointestinal Hemor | 2011 |
Aspirin in the prevention of cancer.
Topics: Age Factors; Anticarcinogenic Agents; Aspirin; Clinical Trials as Topic; Gastrointestinal Hemorrhage | 2011 |
Aspirin in the prevention of cancer.
Topics: Anticarcinogenic Agents; Aspirin; Chronic Disease; Gastrointestinal Hemorrhage; Humans; Iron; Neopla | 2011 |
Cost-effectiveness analysis: cardiovascular benefits of proton pump inhibitor co-therapy in patients using aspirin for secondary prevention.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cohort Studies; Cost-Benefit Analy | 2011 |
Aspirin for the prevention of cardiovascular disease: recommendation statement.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Female; Gastrointestinal Hemorrhag | 2011 |
Aspirin for the prevention of cardiovascular disease.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Decision Making; Evidence-Based Medicine; | 2011 |
The prevalence of co-administration of clopidogrel and proton pump inhibitors.
Topics: Aged, 80 and over; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Drug Therapy, C | 2011 |
Bleeding after percutaneous endoscopic gastrostomy is linked to serotonin reuptake inhibitors, not aspirin or clopidogrel.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Clopidogrel; Cohort Studies; Female; Gastrointe | 2011 |
A retrospective study demonstrating properties of nonvariceal upper gastrointestinal bleeding in Turkey.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Comorbidity; Endoscopy, Gastrointestinal; Fe | 2011 |
PPI therapy: PPI plus aspirin for secondary cardiovascular disease prevention.
Topics: Aspirin; Cardiovascular Diseases; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Pr | 2011 |
Antiplatelet and anticoagulant therapy in patients with gastrointestinal bleeding: an 86-year-old woman with peptic ulcer disease.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Drug Interaction | 2011 |
Aspirin's ability to induce intestinal injury in rats is dependent on bile and can be reversed if pre-associated with phosphatidylcholine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile; Bile Acids and Salts; Dose-Response | 2011 |
Coronary artery stents and antiplatelet therapy in patients with cirrhosis.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Fatty Liver; Female; Follow-Up Studies; Gastroi | 2012 |
Should antiplatelets be stopped before gastric mucosectomy? For how long and in whom?
Topics: Aspirin; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Male; Platelet Ag | 2012 |
Aspirin use and bleeding risk after endoscopic submucosal dissection in patients with gastric neoplasms.
Topics: Adenocarcinoma; Adenoma; Aged; Aspirin; Cardiovascular Diseases; Female; Gastric Mucosa; Gastrointes | 2012 |
New data on aspirin and colorectal cancer brings calls for new guidelines, more research.
Topics: Anticarcinogenic Agents; Aspirin; Biomarkers, Tumor; Clinical Trials as Topic; Colorectal Neoplasms; | 2012 |
New look at antiplatelet agent-related peptic ulcer: an update of prevention and treatment.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Gastrointestinal Hemorrhage; Helic | 2012 |
Predictors and time trends in clopidogrel and proton pump inhibitor coprescription with low-dose acetylsalicylic acid.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clopidogrel; D | 2012 |
[Aspirin response and related factors in aged patients].
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Coronary Artery Disease | 2011 |
[Korean guidelines for colonoscopic polypectomy].
Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Polyps; Colonoscopy; Colorectal N | 2012 |
A new model of gastric bleeding induced in rats by aspirin plus clopidogrel under stimulation of acid secretion. Prophylactic effects of antiulcer drugs.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Clopidogrel; Drug Interactions; Famotidine; Gastric Acid; Gastr | 2012 |
Gastrointestinal bleeding associated with antithrombotic therapy in the elderly in Japan.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Asian People; Aspirin; Chi-Square Distribut | 2012 |
Risk factors for colonic diverticular hemorrhage: Japanese multicenter study.
Topics: Aged; Aged, 80 and over; Aspirin; Body Mass Index; Case-Control Studies; Diverticulum, Colon; Female | 2012 |
Individualised PPI prescription in patients on combination antiplatelet therapy and upper gastrointestinal events after percutaneous coronary intervention: a cohort study.
Topics: Acute Coronary Syndrome; Adrenal Cortex Hormones; Adverse Drug Reaction Reporting Systems; Aged; Ang | 2012 |
Daily low-dose aspirin: beware of GI bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Dose-Response Relationshi | 2012 |
Aspirin: the balance between benefits and harms. Preface.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Colonic Neoplasms; Common | 2012 |
Interaction of Helicobacter pylori infection and low-dose aspirin in the upper gastrointestinal tract: implications for clinical practice.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Acid; Gastrointestinal Diseases; Gastroint | 2012 |
Management of acute upper gastrointestinal bleeding: summary of NICE guidance.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspir | 2012 |
Association of aspirin use with major bleeding in patients with and without diabetes.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Case-Control Studies; Cohort Studi | 2012 |
Hemorrhagic complications associated with aspirin: an underestimated hazard in clinical practice?
Topics: Aspirin; Diabetes Mellitus; Female; Gastrointestinal Hemorrhage; Humans; Intracranial Hemorrhages; M | 2012 |
Differences in the severity of small bowel mucosal injury based on the type of aspirin as evaluated by capsule endoscopy.
Topics: Aged; Aspirin; Capsule Endoscopy; Female; Gastrointestinal Hemorrhage; Humans; Intestinal Mucosa; In | 2012 |
Poor awareness of preventing aspirin-induced gastrointestinal injury with combined protective medications.
Topics: Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Attitude of He | 2012 |
Tighter aspirin control urged for patients with diabetes. Taking aspirin increases bleeding risk that is not always outweighed by the potential benefits for patients with low cardiovascular disease risk.
Topics: Aspirin; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Dose-Response Relationship, Drug; Gas | 2010 |
Combining aspirin and proton pump inhibitors: for whom the warning bell tolls?
Topics: Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Hum | 2012 |
Activation of the bile acid receptor GPBAR1 protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs and aspirin in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile; Gastric Mucosa; Gastrointestinal He | 2013 |
Discontinuation of low-dose aspirin therapy after peptic ulcer bleeding increases risk of death and acute cardiovascular events.
Topics: Aged; Aspirin; Cardiovascular Diseases; Cohort Studies; Female; Gastrointestinal Hemorrhage; Humans; | 2013 |
Benefits and risks of aspirin use.
Topics: Aspirin; Diabetes Mellitus; Female; Gastrointestinal Hemorrhage; Humans; Intracranial Hemorrhages; M | 2012 |
Benefits and risks of aspirin use.
Topics: Aspirin; Diabetes Mellitus; Female; Gastrointestinal Hemorrhage; Humans; Intracranial Hemorrhages; M | 2012 |
Gastrointestinal hemorrhage and antithrombotic drug use in geriatric patients.
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Aspirin; Case-Control Studies; Female; Fibrinolytic Agen | 2012 |
Successful resection of complicated bleeding arteriovenous malformation of the jejunum in patients starting dual-antiplatelet therapy just after implanting a drug-eluting coronary stent.
Topics: Arteriovenous Malformations; Aspirin; Clopidogrel; Drug-Eluting Stents; Gastrointestinal Hemorrhage; | 2012 |
Lower gastrointestinal bleeding: incidence, etiology, and outcomes in a population-based setting.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-C | 2013 |
[Gastrointestinal bleeding associated with NSAIDs, antiplatelet therapy and anticoagulant agent].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Gastrointestinal Hemorrhage; Helic | 2012 |
Bleeding risk with aspirin must be balanced against benefit.
Topics: Aspirin; Cardiovascular Diseases; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Hea | 2012 |
The role of aspirin in post-polypectomy bleeding--a retrospective survey.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Diseases; Colonic Polyps; Colonoscop | 2012 |
Massive life-threatening lower gastrointestinal hemorrhage caused by an internal hemorrhoid in a patient receiving antiplatelet therapy: a case report.
Topics: Aged, 80 and over; Aneurysm; Angiography; Aspirin; Brain Infarction; Embolization, Therapeutic; Gast | 2012 |
Know the benefits and risks of daily aspirin therapy. A small dose can have big benefits for many patients with heart disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Dose-Response Relationshi | 2011 |
Basic pain relievers. It's wise to use caution.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induc | 2012 |
Statements of the Malaysian Society of Gastroenterology & Hepatology and the National Heart Association of Malaysia task force 2012 working party on the use of antiplatelet therapy and proton pump inhibitors in the prevention of gastrointestinal bleeding.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Gastrointestinal Hemorrhage; Human | 2013 |
Direct thrombin inhibitors: a case indicating benefit from 'plasmapheresis' in toxicity: a call for establishing "guidelines" in overdose and to find an "antidote"!
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Antithrombins; Aspirin; Atrial Fibrillation; Ben | 2012 |
[Adverse effects of cardiovascular agents in Japan--update 2012].
Topics: Anticoagulants; Antidiuretic Hormone Receptor Antagonists; Aspirin; Benzazepines; Cardiovascular Age | 2012 |
Bleeding risk after invasive procedures in aspirin/NSAID users: polypectomy study in veterans.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Colonic Polyps; Colonoscopy; | 2012 |
Is low-dose aspirin safe for you? If you take daily aspirin, make sure you know why and understand the small but real bleeding risk.
Topics: Aspirin; Cardiovascular Diseases; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Hea | 2012 |
[The risk factors for colonic diverticular bleeding].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calci | 2012 |
Dietary nitrate and reductive polyphenols may potentiate the vascular benefit and alleviate the ulcerative risk of low-dose aspirin.
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Catechin; Gastric Mucosa; Gastrointestinal Hemorr | 2013 |
Upper gastrointestinal lesions in patients receiving clopidogrel anti-platelet therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Endoscopy, Gastrointestinal; Female; Gastrointestinal | 2012 |
Incidence and risk factors of gastrointestinal bleeding in patients on low-dose aspirin therapy after percutaneous coronary intervention in Japan.
Topics: Acute Coronary Syndrome; Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Case-Control Studies; | 2013 |
Risk factors for upper gastrointestinal bleeding in coronary artery disease patients receiving both aspirin and clopidogrel.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Coronary Artery Disease; Female; Gastrointestinal Hem | 2013 |
Blue rubber bleb nevus syndrome.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Colonic Diseases; Gastrointestina | 2002 |
Making medical news and accountability.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Congresses as Topic; Gastrointestinal Hemorrhage; | 2002 |
Risk of upper gastrointestinal bleeding in patients taking low-dose aspirin for the prevention of cardiovascular diseases.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Drug Administration | 2002 |
Aspirin for the prevention of cardiovascular disease: calculating benefit and harm in the individual patient.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Evidence-Based Medicine; Gastrointestinal | 2003 |
Aspirin curbs colon polyps. But for many, bleeding risks may offset benefits.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Neoplasms; Colonic Polyps; Gastrointestina | 2003 |
Morbidity of transrectal ultrasonography-guided prostate biopsies in patients after the continued use of low-dose aspirin.
Topics: Aspirin; Biopsy, Needle; Blood; Cohort Studies; Gastrointestinal Hemorrhage; Hematuria; Hemorrhage; | 2003 |
Celecoxib versus diclofenac and omeprazole to prevent recurrent ulcer bleeding.
Topics: Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter | 2003 |
Delayed life-threatening hemorrhage after transrectal prostate needle biopsy.
Topics: Aspirin; Biopsy, Needle; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregatio | 2003 |
Low frequency of upper gastrointestinal complications in a cohort of high-risk patients taking low-dose aspirin or NSAIDS and omeprazole.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; | 2003 |
Do nonsteroidal anti-inflammatory drugs affect the outcome of patients admitted to hospital with lower gastrointestinal bleeding?
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Transfusion; Female; Gastrointe | 2003 |
Good news about gut-friendly aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; Platelet Aggr | 2003 |
High incidence of clopidogrel-associated gastrointestinal bleeding in patients with previous peptic ulcer disease.
Topics: Aged; Aspirin; Clopidogrel; Cohort Studies; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; | 2003 |
High incidence of clopidogrel-associated gastrointestinal bleeding in patients with previous peptic ulcer disease.
Topics: Aged; Aspirin; Clopidogrel; Cohort Studies; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; | 2003 |
High incidence of clopidogrel-associated gastrointestinal bleeding in patients with previous peptic ulcer disease.
Topics: Aged; Aspirin; Clopidogrel; Cohort Studies; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; | 2003 |
High incidence of clopidogrel-associated gastrointestinal bleeding in patients with previous peptic ulcer disease.
Topics: Aged; Aspirin; Clopidogrel; Cohort Studies; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; | 2003 |
[Gastrointestinal hemorrhage after salicylic acid therapy in peptic ulcer of long duration].
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Melena; Peptic Ulcer; Salicylic Acid | 1955 |
Aspirin and gastric haemorrhage.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Stomach; Stomach Diseases | 1955 |
[Gastric hemorrhage following acetylsalicylic acid ingestion].
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Stomach; Stomach Diseases | 1957 |
Salicylates and gastric hemorrhage. I. Occult bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Salicylates; Stomach; Stomach Diseases | 1957 |
Salicylates and gastric hemorrhage. II. Manifest bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Salicylates; Stomach; Stomach Diseases | 1957 |
Bleeding from the upper part of the gastrointestinal tract secondary to ingestion of acetylsalicylic acid (aspirin).
Topics: Aspirin; Gastrointestinal Hemorrhage; Gastrointestinal Tract; Hemorrhage; Humans | 1958 |
[Gastroduodenal ulcers and digestive hemorrhages induced by aspirin].
Topics: Aspirin; Gastrointestinal Hemorrhage; Gastrointestinal Tract; Hemorrhage; Humans; Peptic Ulcer | 1958 |
Occult blood in faeces after administration of aspirin.
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Feces; Gastrointestinal Hemorrhage; Hemorrhage; Humans; O | 1958 |
[Digestive hemorrhages & gastroduodenal ulcers caused by aspirin; concerning 52 cases].
Topics: Aspirin; Gastrointestinal Hemorrhage; Gastrointestinal Tract; Hemorrhage; Humans; Peptic Ulcer; Pept | 1958 |
Aspirin and gastric haemorrhage.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Stomach; Stomach Diseases | 1959 |
[Digestive hemorrhages induced by the ingestion of acetylsalicylate].
Topics: Aspirin; Digestion; Eating; Gastrointestinal Hemorrhage; Hemorrhage; Humans | 1960 |
Aspirin and gastrointestinal bleeding. Chromate blood loss studies.
Topics: Aspirin; Chromates; Gastrointestinal Hemorrhage; Hemorrhage; Humans | 1961 |
[Gastric hemorrhage after aspirin].
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Stomach Diseases | 1961 |
[Hemorrhage of the digestive system caused by the ingestion of acetylsalicylic acid (aspirin)].
Topics: Aspirin; Digestive System; Eating; Gastrointestinal Hemorrhage; Hemorrhage | 1960 |
[Severe digestive hemorrhage following the prolonged absorption of aspirin].
Topics: Aspirin; Digestion; Gastrointestinal Hemorrhage; Hemorrhage | 1961 |
Effect of anticoagulant therapy upon aspirin-induced gastrointestinal bleeding.
Topics: Anticoagulants; Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans | 1961 |
Aspirin and gastric bleeding. Gastroscopic observations, with review of literature.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage | 1961 |
[Allergy to aspirin. Gastric nemorrnages preceding the appearance of asthma, urticaria or Quincke's edema].
Topics: Angioedema; Aspirin; Asthma; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Hypersensitivity; Urti | 1960 |
[The ability of acetylsalicylic acid to cause gastrointestinal hemorrhages as determined by benzidine reactions in the feces].
Topics: Aspirin; Benzidines; Feces; Gastrointestinal Hemorrhage; Hemorrhage; Humans | 1960 |
Aspirin, gastrointestinal bleeding, and peptic ulcer.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Peptic Ulcer; Peptic Ulcer Hemorrhage | 1960 |
Drug-induced gastrointestinal bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage | 1962 |
Stomach damage from aspirin, steroids and antimetabolites.
Topics: Adrenal Cortex Hormones; Antimetabolites; Antineoplastic Agents; Aspirin; Gastrointestinal Hemorrhag | 1962 |
Aspirin preperations and their noxious effect on the gastro-intestinal tract.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans | 1962 |
Aspirin and gastrointestinal blood loss.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans | 1963 |
[Hemorrhage from the digestive tract caused by the ingestion of aspirin].
Topics: Aspirin; Eating; Gastrointestinal Hemorrhage; Hemorrhage; Humans | 1963 |
[Aspirin used chronic rheumatoid arthritis patients and chronic gastrointestinal bleeding].
Topics: Arthritis, Rheumatoid; Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans | 1963 |
Salicylates and gastrointestinal bleeding. Acetylsalicylic acid and aspirin derivatives.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Salicylates | 1962 |
[DIGESTIVE HEMORRHAGE PRODUCED BY SALICYLATES].
Topics: Aspirin; Digestion; Gastrointestinal Hemorrhage; Hemorrhage; Salicylates; Toxicology | 1963 |
[EFFECT ON ASPIRIN OF BLEEDING FROM THE DIGESTIVE SYSTEM].
Topics: Aspirin; Digestive System; Gastrointestinal Hemorrhage; Hemorrhage; Toxicology | 1963 |
MANAGEMENT OF RHEUMATOID ARTHRITIS IN THE ELDERLY PATIENT.
Topics: Adrenal Cortex Hormones; Aged; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Arthritis; Arthri | 1963 |
THE MANAGEMENT OF GASTROINTESTINAL HEMORRHAGE.
Topics: Aspirin; Diagnosis; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Peptic Ulcer Hemorrhage; Steroi | 1963 |
[ACUTE DIGESTIVE HEMORRHAGES].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticoagulants; Aspirin; Gastrointestinal Hemo | 1963 |
[IS ASPIRIN A DANGEROUS DRUG?].
Topics: Anemia; Anemia, Hypochromic; Angioedema; Anticoagulants; Aspirin; Asthma; Blood Coagulation Disorder | 1963 |
[RECENT ANALGESICS, ANTIRHEUMATIC AGENTS AND URICOSURIC AGENTS].
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antirheumatic Agents; Aspirin; Colc | 1963 |
[RECENT ACQUISITIONS IN INTERNAL MEDICINE IN RELATION TO: CARDIOLOGY, DERMATOLOGY, GASTROENTEROLOGY, IMMUNOLOGY, NEPHROLOGY AND PNEUMOLOGY. IV. GASTROENTEROLOGY].
Topics: Aspirin; Bile Pigments; Chemical and Drug Induced Liver Injury; Dermatology; Gastroenterology; Gastr | 1963 |
INDOMETHACIN IN RHEUMATIC DISEASES. A CONTROLLED CLINICAL TRIAL.
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Biomedical Research; Drug Hypersensitivity; Gastrointesti | 1964 |
GASTRO-INTESTINAL BLEEDING.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Chromium Isotopes; Gastr | 1964 |
EFFECTS OF ASPIRIN, ACETAMINOPHEN, AND SALICYLAMIDE ON GASTRIC MUCOSA OF DOGS.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Dogs; Gastric Mucosa; Ga | 1964 |
[DIGESTIVE COMPLICATIONS INITIATED BY ASPIRIN ADMINISTERED BY THE ORAL ROUTE].
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Occult Blood; Peptic Ulcer; Toxicology | 1964 |
[EFFECT OF ASPIRIN ON HEMORRHAGES FROM THE DIGESTIVE TRACT].
Topics: Aspirin; Drug Hypersensitivity; Gastrointestinal Hemorrhage; Gastrointestinal Tract; Hemorrhagic Dis | 1964 |
A CASE OF THE BEMUSED MEDIC.
Topics: Aspirin; Colon; Depression; Diagnosis, Differential; Diverticulitis; Diverticulitis, Colonic; Gastro | 1964 |
ASPIRIN-INDUCED HAEMATEMESIS.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hematemesis; Hemorrhage; Humans; Melena; Toxicology | 1964 |
EFFECT OF PARACETAMOL (N-ACETYL-P-AMINOPHENOL) ON GASTROINTESTINAL BLEEDING.
Topics: Acetaminophen; Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Occult Blood; Pharmacology; | 1964 |
[PATHOGENESIS OF GASTROINTESTINAL HEMORRHAGE FOLLOWING ASPIRIN THERAPY].
Topics: 17-Hydroxycorticosteroids; Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Peptic Ulcer; T | 1964 |
[THE SALTS OF ACETYLSALICYLIC ACID ARE ALSO DANGEROUS].
Topics: Anemia; Anemia, Hypochromic; Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Melena; Salts | 1964 |
THE GASTRIC MUCOSA IN RADIOLOGICALLY NEGATIVE ACUTE GASTROINTESTINAL BLEEDING.
Topics: Aspirin; Biopsy; Duodenal Ulcer; Gastric Acidity Determination; Gastric Mucosa; Gastritis; Gastroint | 1964 |
TOXIC EFFECTS OF ASPIRIN AND PHENACETIN.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hematologic Diseases; Hemorrhage; Phenacetin; Toxicology | 1965 |
A STUDY OF THE GASTRIC LESIONS INDUCED BY ASPIRIN IN LABORATORY ANIMALS.
Topics: Animals; Animals, Laboratory; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Guinea Pigs; Hem | 1964 |
A STUDY OF THE GASTRIC LESIONS INDUCED IN LABORATORY ANIMALS BY SOLUBLE AND BUFFERED ASPIRIN.
Topics: Animals; Animals, Laboratory; Antacids; Aspirin; Buffers; Fasting; Gastric Mucosa; Gastrointestinal | 1964 |
PARACETAMOL OR ASPIRIN?
Topics: Acetaminophen; Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Toxicology | 1965 |
[IATROGENIC DISEASE CAUSED BY ASPIRIN].
Topics: Aspirin; Gastrointestinal Hemorrhage; Geriatrics; Hemorrhage; Iatrogenic Disease; Toxicology | 1965 |
[ONCE MORE ON THE HAZARDS OF ACETYLSALICYLIC ACID, ITS SALTS AND COMBINATIONS].
Topics: Antacids; Aspirin; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Hemorrhage; Salts; Toxicology | 1964 |
DAMAGE TO THE GASTRIC MUCOSA: EFFECTS OF SALICYLATES AND STIMULATION.
Topics: Absorption; Animals; Aspirin; Bethanechol Compounds; Denervation; Dogs; Gastric Mucosa; Gastrins; Ga | 1965 |
ASPIRIN AND GASTROINTESTINAL BLEEDING.
Topics: Aspirin; Drug Therapy; Gastrointestinal Hemorrhage; Hemorrhage; Toxicology | 1965 |
[Digestive hemorrhages after administration of acetylsalicylic acid. Contributions to their pathogenesis, prophylaxis and treatment].
Topics: Aspirin; Digestion; Gastrointestinal Hemorrhage; Hemorrhage; Humans | 1960 |
Drug-induced gastrointestinal bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage | 1961 |
Gastritis hemorrhagica medicamentosa salicylas.
Topics: Aspirin; Gastritis; Gastrointestinal Hemorrhage; Humans; Salicylates | 1962 |
Aspirin and gastric bleeding: further studies of calcium aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium; Gastrointestinal Hemorrhage; Humans; Pept | 1961 |
Low-dose aspirin and gastrointestinal hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointe | 2003 |
[Before polyp removal. To stop or not to stop ASA?].
Topics: Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Polyps; Endoscopy; Ga | 2003 |
Intestinal bleeding associated with acetylsalicylic acid.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Intestines | 1951 |
Gastrointestinal hemorrhage from a large dose of acetylsalicylic acid.
Topics: Aspirin; Gastrointestinal Hemorrhage; Gastrointestinal Tract; Hemorrhage; Humans; Vitamin K | 1951 |
The risk of upper gastrointestinal bleeding in elderly users of aspirin and other non-steroidal anti-inflammatory drugs: the role of gastroprotective drugs.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Administration Sched | 2003 |
Concomitant use of buffered and enteric-coated low-dose aspirin products and antisecretory drugs.
Topics: Administration, Oral; Aspirin; Cardiovascular Diseases; Databases, Factual; Drug Prescriptions; Gast | 2004 |
Upper gastrointestinal haemorrhage following cardiac surgery: a comparative study with vascular surgery patients from a single centre.
Topics: Aged; Aspirin; Cardiac Surgical Procedures; Coronary Artery Bypass; Duodenal Ulcer; Female; Gastroin | 2004 |
Postpolypectomy lower gastrointestinal bleeding: potential role of aspirin.
Topics: Age Distribution; Aged; Aged, 80 and over; Aspirin; Blood Transfusion; Case-Control Studies; Colonic | 2004 |
Warfarin and aspirin use and the predictors of major bleeding complications in atrial fibrillation (the Framingham Heart Study).
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Female; Gastrointestin | 2004 |
[Prescribing patterns of rofecoxib in the primary care setting: results of a French survey].
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Arthritis; Arth | 2004 |
Prevention of aspirin-induced gastroduodenal damage: H. pylori infection eradication versus proton pump inhibitors or both.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Aspirin; Dose-Response Relationship | 2004 |
Research in the aged.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Gastrointestinal He | 2004 |
Multiple small-bowel diaphragms: a cause of obscure GI bleeding diagnosed by capsule endoscopy.
Topics: Aged; Anemia, Iron-Deficiency; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Constriction, Patho | 2004 |
Effect of vitamin C-releasing acetylsalicylic acid on gastric mucosal damage before and after Helicobacter pylori eradication therapy.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Aspirin; Blotting, Wester | 2004 |
[Heparin as a substitute for acetylsalicylic acid in polypectomy?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Colonic Polyps; Contraindications; | 2005 |
Biopsy of the prostate guided by transrectal ultrasound: relation between warfarin use and incidence of bleeding complications.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Biopsy; Blood; Fibrinolytic Agents; Follow-Up Stud | 2005 |
[Gastrointestinal bleeding during low dose acetylsalicylic acid. Is Godamed-100 TAH an alternative to conventional ASS preparations?].
Topics: Aspirin; Cardiovascular Diseases; Drug Combinations; Gastrointestinal Hemorrhage; Glycine; Humans; P | 2005 |
Clopidogrel versus aspirin and esomeprazole to prevent recurrent bleeding.
Topics: Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Gastroi | 2005 |
Changes in characteristics and outcome of acute upper gastrointestinal haemorrhage: a comparison of epidemiology and practices between 1996 and 2000 in a multicentre French study.
Topics: Acute Disease; Adolescent; Adult; Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; A | 2005 |
Epidemiological modelling of routine use of low dose aspirin for the primary prevention of coronary heart disease and stroke in those aged > or =70.
Topics: Aged; Aged, 80 and over; Aspirin; Female; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; | 2005 |
When it comes to aspirin, men and women are not equal: aspirin acts differently in women.
Topics: Aspirin; Cardiovascular Diseases; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Pl | 2005 |
[Gastrointestinal hemorrhages with low dosage acetylsalicylic acid].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biotransformation; Dose-Response Relationship, Dru | 2005 |
Study for determination of the optimal cessation period of therapy with anti-platelet agents prior to invasive endoscopic procedures.
Topics: Adult; Aspirin; Bleeding Time; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration | 2005 |
A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with nonsteroidal antiinflammatory drug use.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointestinal Diseases; Gastroint | 2005 |
Upper gastrointestinal haemorrhage associated with low-dose aspirin and anti-thrombotic drugs - a 6-year analysis and comparison with non-steroidal anti-inflammatory drugs.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Prescriptions; Female; Fibrinoly | 2005 |
[Clopidogrel and upper gastrointestinal hemorrhage].
Topics: Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibitors; Practice | 2005 |
Minidose aspirin and gastrointestinal bleeding--a retrospective, case-control study in hospitalized patients.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Dose-Response Relation | 2005 |
[Active lower gastrointestinal bleeding due to appendiceal ulcer].
Topics: Appendectomy; Appendix; Aspirin; Cecal Diseases; Colonoscopy; Combined Modality Therapy; Erythrocyte | 2005 |
No one-size-fits-all for aspirin and elders.
Topics: Aged; Aspirin; Cerebral Hemorrhage; Female; Gastrointestinal Hemorrhage; Humans; Male; Myocardial In | 2005 |
Safety and efficacy of nasogastric intubation for gastrointestinal bleeding after myocardial infarction: an analysis of 125 patients at two tertiary cardiac referral hospitals.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Female; Fibrinolytic Agents; Gastrointestinal Hemo | 2005 |
[Antiplatelet drugs and gastrointestinal bleeding: numquam periclum sine periclo vincitur].
Topics: Age Factors; Aged; Aged, 80 and over; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer A | 2005 |
[Characteristics of colon cancer diagnosed in patients taking aspirin or warfarin].
Topics: Aged; Anticoagulants; Aspirin; Cardiovascular Diseases; Colonic Neoplasms; Female; Gastrointestinal | 2005 |
Upper gastrointestinal bleeding associated with antiplatelet drugs.
Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Antacids; Aspirin; Case-Control Studies; Gastroint | 2006 |
Upper gastrointestinal mucosal abnormalities and blood loss complicating low-dose aspirin and antithrombotic therapy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Dipyrida | 2006 |
[Significance of the stool occult blood test in patients with thrombotic disease under treatment with low dose aspirin].
Topics: Aged; Aged, 80 and over; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; Occult Blood; T | 2005 |
Primary care physician perceptions of non-steroidal anti-inflammatory drug and aspirin-associated toxicity: results of a national survey.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Attitude of Health Personnel; Cardiot | 2006 |
[Gastric protection and treatment with low-dose aspirin].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; | 2006 |
[Recommendation with serious adverse effects].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Cyclooxygenase Inhibitors; G | 2006 |
Summaries for patients. The cost-effectiveness of aspirin, statins, or both drugs in the primary prevention of heart disease.
Topics: Aspirin; Computer Simulation; Coronary Disease; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Com | 2006 |
Aspirin, statins, or both drugs for the primary prevention of coronary heart disease events in men: a cost-utility analysis.
Topics: Aspirin; Computer Simulation; Coronary Disease; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Com | 2006 |
Clopidogrel and metoprolol in myocardial infarction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; | 2006 |
Alcohol and aspirin in combination with dexamethasone causes gastrointestinal bleeding at high altitude.
Topics: Adult; Alcohol Drinking; Altitude; Altitude Sickness; Aspirin; Dexamethasone; Drug Synergism; Gastro | 2006 |
Upper gastrointestinal bleeding after hip and knee arthroplasty.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Arthroplast | 2006 |
Aspirin use cuts colon cancer risk, but may have side effect.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Colonic Neoplasms; Female | 2006 |
A health impact assessment of increased aspirin use in Wales.
Topics: Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation Inhibito | 2006 |
Increased use of selective serotonin reuptake inhibitors in patients admitted with gastrointestinal haemorrhage: a multicentre retrospective analysis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Black or African American; B | 2006 |
Statins are associated with lower risk of gastrointestinal bleeding in patients with unstable coronary syndromes: analysis of the Orbofiban in Patients with Unstable coronary Syndromes-Thrombolysis In Myocardial Infarction 16 (OPUS-TIMI 16) trial.
Topics: Acute Disease; Administration, Oral; Aged; Alanine; Anticoagulants; Aspirin; Coronary Disease; Femal | 2006 |
Incidence and predictors of upper gastrointestinal bleeding in patients receiving low-dose aspirin for secondary prevention of cardiovascular events in patients with coronary artery disease.
Topics: Aged; Aspirin; Body Mass Index; Comorbidity; Coronary Artery Disease; Dose-Response Relationship, Dr | 2006 |
[Epidemiology of gastrointestinal bleeding in the elderly].
Topics: Age Factors; Aged; Aged, 80 and over; Angiodysplasia; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2006 |
Dose of aspirin and bleeding risks.
Topics: Aspirin; Dose-Response Relationship, Drug; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; | 2006 |
Hospitalization for gastrointestinal bleeding associated with non-steroidal anti-inflammatory drugs among elderly patients using low-dose aspirin: a retrospective cohort study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase | 2007 |
ESPRIT trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Ischemia; Dipyridamole; Drug Interactions; G | 2006 |
Clinical outcome in upper gastrointestinal bleeding complicating low-dose aspirin and antithrombotic drugs.
Topics: Aspirin; Female; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Platel | 2006 |
Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding: population based case-control study.
Topics: Aged; Aspirin; Case-Control Studies; Drug Therapy, Combination; Female; Fibrinolytic Agents; Gastroi | 2006 |
[Antiplatelet therapy after aspirin-induced upper gastrointestinal bleeding].
Topics: Anti-Ulcer Agents; Aspirin; Clopidogrel; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combinatio | 2006 |
Silent myocardial ischemia in coronary artery disease patients under aspirin therapy presenting with upper gastrointestinal hemorrhage.
Topics: Aged; Aspirin; Coronary Disease; Electrocardiography; Female; Gastrointestinal Hemorrhage; Hospital | 2007 |
[Platelet inhibition and gastric problems].
Topics: Anti-Ulcer Agents; Aspirin; Clopidogrel; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Hum | 2007 |
Risk of low-dose aspirin: emphasis on outliers undermines the credibility of the conclusions.
Topics: Adrenal Cortex Hormones; Aging; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Ca | 2007 |
Prevention of vascular events in atrial fibrillation.
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Pro | 2007 |
Risks and benefits of COX-2 inhibitors vs non-selective NSAIDs: does their cardiovascular risk exceed their gastrointestinal benefit? A retrospective cohort study.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2 I | 2007 |
Clinical use of evidence-based medicine--clinical questions. Is low-dose aspirin a better choice in patients with coronary artery disease and bleeding risks?
Topics: Aspirin; Coronary Disease; Evidence-Based Medicine; Gastrointestinal Hemorrhage; Humans; Platelet Ag | 2007 |
Enteric coated aspirin.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors | 2007 |
A risk score to predict silent myocardial ischemia in patients with coronary artery disease under aspirin therapy presenting with upper gastrointestinal hemorrhage.
Topics: Aged; Aspirin; Coronary Artery Disease; Female; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Hu | 2007 |
Aspirin for primary prevention of cardiovascular disease in Japan.
Topics: Aspirin; Cardiovascular Diseases; Gastrointestinal Hemorrhage; Humans; Japan; Platelet Aggregation I | 2007 |
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2007 |
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2007 |
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2007 |
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2007 |
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2007 |
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2007 |
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2007 |
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2007 |
Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2007 |
Hospitalization for gastrointestinal adverse events attributable to the use of low-dose aspirin among patients 50 years or older also using non-steroidal anti-inflammatory drugs: a retrospective cohort study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Cyclooxyg | 2007 |
Upper gastrointestinal bleeding and the changing use of COX-2 non-steroidal anti-inflammatory drugs and low-dose aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2 Inhibitors; Dose-Response Relatio | 2007 |
Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel, and enoxaparin in acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Drug | 2008 |
Portal vein thrombosis associated with coronary artery bypass surgery.
Topics: Aged; Aspirin; Bacteremia; Clopidogrel; Coagulase; Coronary Artery Bypass; Esophageal and Gastric Va | 2008 |
Risk of upper gastrointestinal bleeding and the degree of serotonin reuptake inhibition by antidepressants: a case-control study.
Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Aspirin; Case-Control S | 2008 |
Combined antithrombotic therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; | 2008 |
Management of upper gastrointestinal haemorrhage complicating dual anti-platelet therapy.
Topics: Aged; Aspirin; Blood Transfusion; Clopidogrel; Coronary Disease; Drug Therapy, Combination; Endoscop | 2008 |
Prophylactic use of gastro-protective agents in patients on low-dose aspirin.
Topics: Adult; Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Male; M | 2008 |
A case-control study of the association between polymorphisms of the endothelial nitric oxide synthase and glycoprotein IIIa genes and upper gastrointestinal bleeding in users of low-dose aspirin.
Topics: Aged; Alcohol Drinking; Aspirin; Case-Control Studies; Female; Gastrointestinal Hemorrhage; Gene Fre | 2008 |
Single antiplatelet therapy for patients with previous gastrointestinal bleeds.
Topics: Aged; Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Therapy, Combination; Female; Gastrointest | 2008 |
Gastric protection and gastrointestinal bleeding with aspirin thromboprophylaxis in hip and knee joint replacements.
Topics: Aged; Anti-Ulcer Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; D | 2008 |
Aspirin prescription and outcomes in hemodialysis patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; | 2008 |
Reappraisal of the effects of aspirin on the stomach.
Topics: Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Risk; Stomach; Time Fact | 1980 |
Aspirin and gastric damage.
Topics: Animals; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer | 1980 |
Effect of paracetamol coadministration on aspirin-induced gastrointestinal bleeding in dogs.
Topics: Acetaminophen; Animals; Aspirin; Dogs; Gastrointestinal Hemorrhage; Male | 1981 |
The protective effect of deglycyrrhinized liquorice against aspirin and aspirin plus bile acid-induced gastric mucosal damage, and its influence on aspirin absorption in rats.
Topics: Animals; Aspirin; Deoxycholic Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Glycyrrhiza; Intest | 1983 |
Acute gastric microbleeding after aspirin ingestion, compared with a similar dose of fenbufen by measurement of haemoglobin in gastric aspirates.
Topics: Adult; Aspirin; Female; Gastric Juice; Gastrointestinal Hemorrhage; Hemoglobins; Humans; Male; Pheny | 1983 |
1,300 mg of aspirin daily does not cause positive fecal hemoccult tests.
Topics: Adolescent; Adult; Aspirin; Dietary Fiber; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle | 1983 |
Comparative effects of aspirin and enteric-coated aspirin on loss of chromium 51-labeled erythrocytes from the gastrointestinal tract.
Topics: Adolescent; Adult; Aspirin; Chromium Radioisotopes; Dose-Response Relationship, Drug; Gastrointestin | 1984 |
Salicylate-induced occult gastrointestinal blood loss: comparison between different oral and parenteral forms of acetylsalicylates and salicylates.
Topics: Administration, Oral; Aspirin; Dosage Forms; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Hu | 1984 |
Aspirin-induced damage in the dog Heidenhain pouch and cytoprotection with 16,16-dimethyl PGE2.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Aspirin; Disease Models, Animal; Dogs; Female; Gastric Muco | 1984 |
Effect of cimetidine on net ion fluxes across the rat gastric mucosa during mucosal damage after gastric ischemia and after intravenous acetylsalicylic acid.
Topics: Animals; Aspirin; Biological Transport; Chromium Radioisotopes; Cimetidine; Drug Interactions; Elect | 1984 |
The ulcerogenic potential of copper aspirinate seems to be more imaginary than real.
Topics: Animals; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Rats; Stomach Ulcer | 1984 |
Correlations between changes in indicators of gastric mucosal barrier integrity at time of exposure to "barrier breakers" and extent of hemorrhagic erosions one hour later.
Topics: Animals; Aspirin; Ethanol; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Mannitol; Prognosis; | 1984 |
Drugs in the treatment of thrombo-embolic disease--part I.
Topics: Administration, Oral; Anticoagulants; Aspirin; Blood Platelets; Carotid Artery Diseases; Cerebrovasc | 1983 |
Prevention of the gastrotoxicity of aspirin and related drugs in rats by lithium salts and sodium thiocyanate.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cold Temperature; Female; Gastric Mucosa; Gastrointestin | 1983 |
Analgesic intake and the risk of acute upper gastrointestinal bleeding.
Topics: Acetaminophen; Analgesics; Aspirin; Female; Gastrointestinal Hemorrhage; Hematemesis; Humans; Male; | 1983 |
Primary drug therapy: aspirin vs. the nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Central Nervous System Diseases; Chemical and Drug Ind | 1983 |
[Drug-induced hemorrhages of the gastrointestinal tract].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Ethacrynic Acid; Gastrit | 1983 |
Interactions between ethanol and acetylsalicylic acid in damaging the rat gastric mucosa.
Topics: Animals; Aspirin; Drug Interactions; Ethanol; Gastric Mucosa; Gastrointestinal Hemorrhage; Ions; Mal | 1983 |
Effect of synthetic prostaglandin E1 analog on aspirin-induced gastric bleeding and secretion.
Topics: Alprostadil; Aspirin; Calcium; Chlorides; DNA; Double-Blind Method; Drug Evaluation; Gastric Juice; | 1983 |
Comparison of fecal blood loss after use of aspirin and suprofen.
Topics: Adult; Aspirin; Chromium Radioisotopes; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Ma | 1983 |
1,300 mg of aspirin daily.
Topics: Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Occult Blood | 1983 |
Occult gastrointestinal blood loss in marathon runners.
Topics: Adult; Age Factors; Aspirin; Feces; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Occult B | 1984 |
A platelet release defect induced by aspirin or penicillin G does not increase gastrointestinal blood loss in thrombocytopenic rabbits.
Topics: Animals; Aspirin; Blood Platelet Disorders; Busulfan; Gastrointestinal Hemorrhage; Male; Penicillin | 1984 |
Aspirin and the stomach.
Topics: Aspirin; Drug Administration Schedule; Gastrointestinal Hemorrhage; Humans; Stomach Ulcer | 1981 |
Aspirin and the stomach.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Male | 1981 |
The effect of antacids on the occurrence of bile acid and aspirin-induced gastric lesions in rats.
Topics: Aluminum Hydroxide; Animals; Antacids; Aspirin; Bile Acids and Salts; Deoxycholic Acid; Drug Combina | 1980 |
Gastric distress evoked by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Fenoprofen; Gastrointestinal Hemorrhage; Humans; Stomach Diseases | 1980 |
Bleeding during acetylsalicylic acid and anticoagulant therapy in patients with reduced platelet reactivity after aortic valve replacement.
Topics: Anticoagulants; Aortic Valve; Aspirin; Bleeding Time; Blood Platelets; Cerebral Hemorrhage; Double-B | 1980 |
Comparative evaluation of gastrointestinal blood loss in the feces of rats following Pepto-Bismol liquid and aspirin administration.
Topics: Animals; Aspirin; Bismuth; Feces; Gastrointestinal Hemorrhage; Male; Occult Blood; Organometallic Co | 1980 |
Endoscopic evaluation of the effects of aspirin, buffered aspirin, and enteric-coated aspirin on gastric and duodenal mucosa.
Topics: Adult; Aspirin; Buffers; Duodenum; Endoscopy; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastrosco | 1980 |
Influence of broperamole, a new antiinflammatory agent, on gastrointestinal microbleeding in the dog.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Feces; Gastrointestinal Hemorrhage; Iron Radioisot | 1980 |
Risk of overt bleeding following aspirin.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Risk | 1980 |
Gastro-intestinal haemorrhage following ingestion of 'Alka-Seltzer'.
Topics: Adult; Aged; Antacids; Aspirin; Bicarbonates; Citrates; Drug Combinations; Female; Gastrointestinal | 1980 |
Effects of aspirin and acetaminophen in gastrointestinal hemorrhage. Results from the Boston Collaborative Drug Surveillance Program.
Topics: Acetaminophen; Adult; Age Factors; Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Hospitalizati | 1981 |
Upper gastrointestinal tract bleeding. Predisposing factors, diagnosis, and therapy.
Topics: Angiography; Aspirin; Digestive System; Electrocoagulation; Endoscopy; Gastrointestinal Hemorrhage; | 1981 |
Acetylsalicylic acid-induced gastrointestinal bleeding determined by a 51Cr method on a day-to-day basis.
Topics: Adult; Aspirin; Chromium Radioisotopes; Double-Blind Method; Feces; Gastrointestinal Hemorrhage; Hum | 1980 |
Does aspirin prolong bleeding from gastric biopsies in man?
Topics: Aspirin; Biopsy; Bleeding Time; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Humans | 1981 |
Drug-induced gastrointestinal ulceration: a review.
Topics: Anti-Inflammatory Agents; Aspirin; Esophageal Diseases; Gastrointestinal Hemorrhage; Humans; Peptic | 1980 |
Aspirin and bile acid induced gastric mucosal damage: protection by prostaglandins and antacids.
Topics: Animals; Antacids; Aspirin; Bile Acids and Salts; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; | 1981 |
Severe upper gastrointestinal bleeding. Part I: Causes, pathogenesis and methods of diagnosis.
Topics: Angiography; Aspirin; Duodenal Ulcer; Endoscopy; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans | 1981 |
Controlled comparison of gastric lesions and gastrointestinal blood loss with fluproquazone and acetylsalicylic acid (ASA) in healthy subjects.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Factors; Blood Platelets; Female | 1981 |
[Hematemesis and melena in children after administration of salicylates (author's transl)].
Topics: Aspirin; Child; Female; Gastrointestinal Hemorrhage; Hematemesis; Humans; Infant; Male; Melena | 1981 |
Risk-benefit analysis of warfarin therapy in Hancock mitral valve replacement.
Topics: Adult; Aged; Aspirin; Bioprosthesis; Cerebral Hemorrhage; Female; Gastrointestinal Hemorrhage; Heart | 1982 |
Piroxicam, aspirin, and gastrointestinal blood loss.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Administration Schedule; Drug Evaluati | 1982 |
Aspirin, ulcer, and intestinal bleeding: what do the data show?
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer | 1982 |
Portal hypertension in children due to thrombosis of the portal vein.
Topics: Adolescent; Aspirin; Catheterization; Child; Child, Preschool; Esophageal and Gastric Varices; Femal | 1982 |
Aspirin-induced bleeding and anxiety.
Topics: Anxiety Disorders; Aspirin; Gastrointestinal Hemorrhage; Humans | 1982 |
Gastrointestinal consequences of treatment with drugs in elderly patients.
Topics: Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Digestive System Physiological Phenom | 1982 |
[Hematemesis in childhood. Use of the fiberscope in diagnosis].
Topics: Adolescent; Aspirin; Child; Child, Preschool; Duodenitis; Endoscopy; Esophagitis; Female; Fiber Opti | 1982 |
[Hemorrhage into the gastrointestinal system as a complication of Acylpyrin therapy].
Topics: Aspirin; Child; Child, Preschool; Gastrointestinal Hemorrhage; Humans; Male | 1982 |
Quantitative determination of gastrointestinal bleeding in rats.
Topics: Animals; Aspirin; Feces; Gastrointestinal Hemorrhage; Heme; Male; Rats; Rats, Inbred Strains; Time F | 1982 |
[Gastrointestinal hemorrhage during treatment of spinal cord injuries].
Topics: Anticoagulants; Aspirin; Gastrointestinal Hemorrhage; Humans; Middle Aged; Postoperative Care; Posto | 1982 |
Ineffectiveness of aspirin and dipyridamole in the treatment of thrombotic thrombocytopenic purpura.
Topics: Adolescent; Adult; Aged; Aspirin; Dipyridamole; Epistaxis; Epoprostenol; Female; Gastrointestinal He | 1982 |
Re: Gastrointestinal blood loss with low-dose aspirin.
Topics: Adaptation, Physiological; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastroi | 1995 |
Aspirin, salicylate and gastrointestinal injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Detergents; Gastric Mucosa; Gas | 1995 |
Which patients taking non-aspirin non-steroidal anti-inflammatory drugs bleed? A case-control study.
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Alcoholism; Anti-Inflammatory Agents, Non-Steroida | 1995 |
[Do we honour those who deserve to be honoured?].
Topics: Anticoagulants; Aspirin; Europe; Gastrointestinal Hemorrhage; Hemorrhage; History, 20th Century; Hum | 1995 |
Use of low-dose aspirin as a preventive measure.
Topics: American Cancer Society; American Heart Association; Aspirin; Cerebral Hemorrhage; Coronary Disease; | 1995 |
[Hemorrhagic angiodysplasia of the right colon after ingestion of non-steroidal anti-inflammatory agents].
Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Colonic Diseases; Flurbiprofen; Gastrointestinal H | 1994 |
Chemical gastro-oesophagitis, upper gastrointestinal haemorrhage and gastroscopic findings following Dettol poisoning.
Topics: Adult; Anti-Infective Agents, Local; Aspirin; Esophagitis; Female; Follow-Up Studies; Gastrointestin | 1995 |
[Can early recurrent hemorrhage in gastroduodenal ulcer be predicted?].
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Ulcer; En | 1994 |
Gastrointestinal blood loss in triathletes: it's etiology and relationship to sports anaemia.
Topics: Adult; Anemia; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Aspirin; Bicycling; Erythrocy | 1995 |
Relation of the use of analgesics and non-steroidal anti-inflammatory drugs (NSAIDs) to upper gastrointestinal bleeding: a preliminary report of a Finnish case-control prospective study.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-C | 1994 |
Adaptation of rat gastric mucosa to aspirin requires mucosal contact.
Topics: Adaptation, Physiological; Animals; Aspirin; Dinoprostone; Gastric Mucosa; Gastritis; Gastrointestin | 1995 |
Do infiltrating leukocytes contribute to the adaptation of human gastric mucosa to continued aspirin administration?
Topics: Adaptation, Physiological; Adult; Aspirin; Biopsy; Gastric Mucosa; Gastritis; Gastrointestinal Hemor | 1994 |
Adverse drug reactions resulting in hospital admission.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Analgesics; Ant | 1994 |
Low-dose acetylsalicylic acid use and hemoglobin levels. Effects in a primary care population.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Family Practice; Female; Gastroint | 1995 |
NSAIDs and gut toxicity.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans | 1994 |
NSAIDs and gut toxicity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; | 1994 |
Mucosal adaptation to aspirin induced gastric damage in humans. Studies on blood flow, gastric mucosal growth, and neutrophil activation.
Topics: Adaptation, Physiological; Adult; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; | 1994 |
The outcome of peptic ulcer haemorrhage in relation to consumption of nonsteroidal anti-inflammatory drugs or aspirin.
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointestinal Hemorr | 1994 |
Preoperative diagnosis of Meckel's diverticulum by pertechnetate scan and laparoscopic resection.
Topics: Adolescent; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Laparoscopy; Male; Meckel | 1994 |
Acute coronary embolism complicating aortic valve endocarditis treated with streptokinase and aspirin. A case report.
Topics: Aortic Valve; Aspirin; Embolism; Endocarditis, Bacterial; Gastrointestinal Hemorrhage; Heart Valve D | 1994 |
Antiplatelet prophylaxis. Consider the protective effect of blood loss from the gut.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Myocardial Infarction | 1994 |
Cost-effectiveness of ticlopidine in preventing stroke in high-risk patients.
Topics: Aged; Aspirin; Cerebrovascular Disorders; Cohort Studies; Cost-Benefit Analysis; Decision Support Te | 1994 |
Nonsteroidal antiinflammatory drugs and upper gastrointestinal hemorrhage in an urban hospital.
Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Transfusion; Case-Control Studi | 1993 |
Gastric mucosal blood flow and neutrophil activation in aspirin-induced gastric mucosal damage in man.
Topics: Adult; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Male; Neutrophils; Platelet Adh | 1993 |
Gastro-duodenal injury associated with intake of 100-325 mg aspirin daily.
Topics: Acute Disease; Aged; Aged, 80 and over; Aspirin; Drug Administration Schedule; Duodenal Ulcer; Femal | 1993 |
Striking prevalence of over-the-counter nonsteroidal anti-inflammatory drug use in patients with upper gastrointestinal hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Confidence Interva | 1994 |
Chronic nicotine intake causes vascular dysregulation in the rat gastric mucosa.
Topics: Animals; Aspirin; Blood Flow Velocity; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Leukotri | 1993 |
The risk of emergency intestinal bleeding among users of acenocoumarin: a population-based cohort study.
Topics: Acenocoumarol; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cas | 1993 |
Retreatment with alteplase for early signs of reocclusion after thrombolysis. The European Cooperative Study Group.
Topics: Adult; Aged; Aspirin; Coronary Angiography; Drug Therapy, Combination; Electrocardiography; Female; | 1993 |
Low-dose aspirin and bleeding in uremia.
Topics: Aspirin; Dose-Response Relationship, Drug; Female; Gastrointestinal Hemorrhage; Humans; Middle Aged; | 1993 |
Gastrointestinal hemorrhage complicating aspirin therapy in acute Kawasaki disease.
Topics: Acute Disease; Aspirin; Child, Preschool; Cimetidine; Erythrocyte Transfusion; Female; gamma-Globuli | 1996 |
Diaspirin cross-linked hemoglobin is efficacious in gut resuscitation as measured by a GI tract optode.
Topics: Animals; Aspirin; Blood Pressure; Fluid Therapy; Gastrointestinal Hemorrhage; Hemoglobins; Intestina | 1996 |
Low dose aspirin in patients with ischemic heart disease may precipitate secondary myocardial infarction.
Topics: Aged; Angina, Unstable; Aspirin; Gastrointestinal Hemorrhage; Hemoglobins; Humans; Middle Aged; Myoc | 1996 |
Asymptomatic chronic gastrointestinal blood loss in patients taking aspirin or warfarin for cardiovascular disease.
Topics: Analysis of Variance; Anticoagulants; Aspirin; Cardiovascular Diseases; Chronic Disease; Cross-Over | 1996 |
Reversible prolonged skin bleeding time in acute gastrointestinal bleeding presumed due to NSAIDs.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ble | 1996 |
Non-steroidal anti-inflammatory drugs and variceal bleeding: a case-control study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studi | 1996 |
A comparison of clinical and endoscopic features of bleeding and non-bleeding peptic ulcer in Singapore.
Topics: Adult; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Endoscopy, Gastroin | 1996 |
Case report: gastrointestinal haemorrhage from jejunal diverticulosis, probably induced by low dose aspirin.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diverticulum; Female; Gastrointestinal Hemor | 1996 |
Safety profile of low-dose aspirin.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hematemesis; Humans; Middle Aged; Platelet Aggregation Inhibit | 1996 |
Effect of combined anticoagulation and low-dose aspirin treatment on upper gastrointestinal bleeding.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents, Non-Steroi | 1997 |
Aspirin related gastrointestinal bleeders have an exaggerated bleeding time response due to aspirin use.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Coagulation; Factor VIII; Fem | 1996 |
Gastric safety and enteric-coated aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Buffers; Gastrointestinal Hemor | 1997 |
Gastric safety and enteric-coated aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Buffers; Gastrointestinal Hemorrhage; Humans; Tabl | 1997 |
Gastric safety and enteric-coated aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Heart Diseases; Human | 1997 |
Aspirin preparation and risk of GI bleeding.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Buffers; Case-Control Stu | 1997 |
Aspirin therapy in diabetes mellitus.
Topics: Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Gastrointestin | 1997 |
Helicobacter pylori and gastric adaptation to repeated aspirin administration in humans.
Topics: Adaptation, Physiological; Adult; Aspirin; DNA; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; | 1997 |
Aspirin effects on colonic mucosal bleeding: implications for colonic biopsy and polypectomy.
Topics: Aspirin; Biopsy; Bleeding Time; Blood Coagulation; Colonic Diseases; Colonoscopy; Endoscopy; Gastroi | 1997 |
Infection of Helicobacter pylori in gastric adaptation to continued administration of aspirin in humans.
Topics: Adaptation, Physiological; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dino | 1998 |
Aspirin for prevention of myocardial infarction. A double-edged sword.
Topics: Aged; Aged, 80 and over; Anemia; Angina, Unstable; Aspirin; Female; Gastrointestinal Hemorrhage; Hum | 1997 |
Aspirin-like drugs cause gastrointestinal injuries by metallic cation chelation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cations; Chelating Agents; Digestive Syst | 1998 |
[Aspirin and surgery].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Diseases; Endoscopy; Gastroi | 1997 |
Do we need high-dose acetylsalicylic acid (ASA) in Kawasaki disease?
Topics: Aspirin; Child, Preschool; Female; Gastrointestinal Hemorrhage; Humans; Immunoglobulins, Intravenous | 1998 |
Guideline on the management of anticoagulation and antiplatelet therapy for endoscopic procedures. American Society for Gastrointestinal Endoscopy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Endoscopy, Gastrointestinal; Gastr | 1998 |
Frequency of major complications of aspirin, warfarin, and intravenous heparin for secondary stroke prevention. A population-based study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Cerebral Hemorrhage; Cerebro | 1999 |
Anti-inflammatory drugs and variceal bleeding: a case-control study.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Esophageal and | 1999 |
Major upper gastrointestinal bleeding and the use of calcium channel blockers.
Topics: Aspirin; Calcium Channel Blockers; Case-Control Studies; Gastrointestinal Hemorrhage; Humans; Hungar | 1999 |
Aspirin, myocardial infarction, and gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dyspepsia; Gastrointestinal Hemorrhage; Humans; My | 1999 |
Aspirin, myocardial infarction, and gastrointestinal bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhoids; Humans; Male; Myocardial Infarction; Platelet Agg | 1999 |
Spontaneous intramural hematoma of the esophagus.
Topics: Aged; Aspirin; Diagnostic Imaging; Esophageal Diseases; Female; Gastrointestinal Hemorrhage; Hematom | 1999 |
NSAIDs and alcohol: never the twain shall mix?
Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase | 1999 |
The risk of acute major upper gastrointestinal bleeding among users of aspirin and ibuprofen at various levels of alcohol consumption.
Topics: Acute Disease; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Contro | 1999 |
H. pylori and risk of ulcer bleeding among users of NSAIDS.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Helicobacter Infectio | 2000 |
"Chap Kaki Tiga" a possible cause of upper gastrointestinal haemorrhage.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Drug Combinations; Gastrointestinal Hemorrhage; Humans | 1996 |
Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Diabetes Mellitus, Experimental; Gastric Acid; Gastric Mucosa; | 2000 |
Nitrovasodilators, low-dose aspirin, other nonsteroidal antiinflammatory drugs, and the risk of upper gastrointestinal bleeding.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Drug Interactions; Dru | 2000 |
Risk of upper gastrointestinal bleeding associated with use of low-dose aspirin.
Topics: Administration, Oral; Adolescent; Adult; Age Distribution; Aged; Anti-Inflammatory Agents, Non-Stero | 2000 |
Coated aspirin no safer.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; Tablets, Ente | 2000 |
Authors' reply on aspirin for primary prevention.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Disease; Gastrointestinal Hemorrhage; Hum | 2001 |
Current approaches to reducing gastrointestinal toxicity of low-dose aspirin.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; | 2001 |
Risk factors for hospitalized gastrointestinal bleeding among older persons. Cardiovascular Health Study Investigators.
Topics: Activities of Daily Living; Age Distribution; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non | 2001 |
Re: Sørensen et al.: low dose aspirin.
Topics: Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Humans; Platelet Aggregation | 2001 |
[Upper gastrointestinal bleeding in patients treated by low-dose aspirin].
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Duodenal Ulcer; Female; France; Gastrointestinal Hemorrhage | 2001 |
Colorectal cancer among users of aspirin and non-steroidal antiinflammatory drugs.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bias; Cardiovascular Diseases; Cohort | 2001 |
Preventing upper gastrointestinal bleeding in patients with Helicobacter pylori infection.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Gastrointestinal Hemorrhage; He | 2001 |
Hospitalisation for upper gastrointestinal bleeding associated with use of oral anticoagulants.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflamma | 2001 |
Elimination of Helicobacter pylori or acid in high-risk users of aspirin or nonsteroidal medications: final answer?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Acid; Gastrointestinal Hemorrhage; Helicob | 2002 |
Efficacy and safety of aspirin in the long-term management of atherothrombosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Blood Platelets; Cardiovascular | 2002 |
Aspirin gets a tentative nod.
Topics: Aspirin; Coronary Disease; Gastrointestinal Hemorrhage; Humans; Risk Assessment; Risk Factors; Strok | 2002 |
Balancing the risks of stroke and upper gastrointestinal tract bleeding in older patients with atrial fibrillation.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Atrial Fibrillation; Decisio | 2002 |
[Do nitrates reduce the risk of drug induced hemorrhage of the upper gastrointestinal tract?].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; Isos | 2001 |
Helicobacter pylori increases the risk of upper gastrointestinal bleeding in patients taking low-dose aspirin.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Female; Gastrointestin | 2002 |
Who should be taking aspirin?
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors | 2002 |
Meckel's diverticulum and mesenterium commune in a patient with gastrointestinal bleeding.
Topics: Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Meckel Diverticulum; Mesentery; Middle Aged; R | 2002 |
Aspirin-induced gastritis and gastrointestinal bleeding.
Topics: Administration, Oral; Aspirin; Blood Platelets; Delayed-Action Preparations; Dose-Response Relations | 1976 |
Interaction of salicylic acid with adenosine and adenosine triphosphate. Potential mechanism of intensifying acetylsalicylic acid-induced GI blood loss.
Topics: Adenosine; Adenosine Triphosphate; Aspirin; Chemical Phenomena; Chemistry; Gastrointestinal Hemorrha | 1976 |
Action of glucagon and aspirin on ionic flux, mucosal blood flow and bleeding in the fundic pouch of dogs.
Topics: Aminopyrine; Animals; Aspirin; Calcium; Denervation; Dogs; Drug Interactions; Female; Gastric Juice; | 1977 |
Cell turnover and loss and the gastric mucosal barrier.
Topics: Aspirin; Cell Division; Cell Survival; DNA; Epithelial Cells; Epithelium; Gastric Mucosa; Gastritis; | 1977 |
[Comparative experimental studies in animals and humans on gastrointestinal blood loss following antirheumatic pharmacotherapy (author's transl)].
Topics: Animals; Aspirin; Gastrointestinal Hemorrhage; Humans; Iron; Iron Radioisotopes; Male; Rats; Salicyl | 1978 |
Aspirin and the gastric mucosa.
Topics: Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Hydrogen-Ion Concentration | 1978 |
Influence of L-glutamine on aspirin-induced gastrointestinal microbleeding in dogs.
Topics: Animals; Aspirin; Dogs; Feces; Gastrointestinal Hemorrhage; Glutamine; Iron Radioisotopes; Male | 1979 |
Upper gastrointestinal haemorrhage in hepatic cirrhosis: causes and relation to hepatic failure and stress.
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aspirin; Chronic Disease; Esophagea | 1977 |
Does aspirin precipitate major gastrointestinal bleeding in patients on haemodialysis?
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Kidney Failure, Chronic; Renal Dialysis; Risk | 1977 |
Drug-induced gastrointestinal bleeding. Report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center.
Topics: Anticoagulants; Aspirin; Chlordiazepoxide; Drug Therapy, Combination; Ethacrynic Acid; Gastrointesti | 1978 |
Drug-induced gastrointestinal bleeding.
Topics: Aspirin; England; Gastrointestinal Hemorrhage; Humans; Wales | 1978 |
[Anti-inflammatory agents in current therapeutics].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi | 1975 |
[Clinical aspects and course of drug-induced upper digestive hemorrhage].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoag | 1976 |
The application of basic principles of drug interaction to clinical practice.
Topics: Aged; Aspirin; Binding Sites; Binding, Competitive; Depression, Chemical; Drug Interactions; Drug Sy | 1975 |
Physical form as a determinant of effect of buffered acetylsalicylate formulations on gi microbleeding.
Topics: Animals; Aspirin; Buffers; Dogs; Gastrointestinal Hemorrhage; Male; Powders; Suspensions; Tablets | 1977 |
New antirheumatic agents: Fenoprofen calcium (Nalfon), naproxen (Naprosyn), and tolmetin sodium (Tolectin).
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Gastrointestinal Hemorrhage; H | 1977 |
[Gastrointestinal hemorrhage during treatment with ibuprofen (Brufen)].
Topics: Aged; Aspirin; Drug Interactions; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Male; Midd | 1977 |
Gastrointestinal blood loss.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Rheumatic Diseases | 1977 |
Effect of repeated aspirin administration on the gastric mucosal barrier and cell turnover.
Topics: Animals; Aspirin; DNA; Dogs; Gastric Mucosa; Gastrointestinal Hemorrhage; Hydrogen; Permeability; So | 1977 |
[Gastrointestinal hemorrhages as a consequence of the side effects of drug substances].
Topics: Aspirin; Blood Volume; Drug-Related Side Effects and Adverse Reactions; Female; Gastrointestinal Hem | 1977 |
Acute upper-gastrointestinal hemorrhage. New observations on an old problem.
Topics: Alcohol Drinking; Aspirin; Duodenal Ulcer; Esophageal and Gastric Varices; Esophagoscopy; Gastritis; | 1978 |
Assessment of gastric mucosal damage: comparative effects of aspirin and fenclofenac on the gastric mucosa of the guinea pig.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; DNA; Gastric Juice; Gastric Mucosa; Gastrointestinal Hem | 1977 |
Gastrointestinal and other side-effects from the use of aspirin and related drugs; biochemical studies on the mechanisms of gastrotoxicity.
Topics: Animals; Aspirin; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Guinea Pigs; Humans; Pregnanc | 1977 |
Gastric mucosal injury from common drugs.
Topics: Adrenal Cortex Hormones; Aspirin; Drug-Related Side Effects and Adverse Reactions; Gastric Mucosa; G | 1978 |
Hemostatic defect in endoscoped upper gut bleeding.
Topics: Alcoholism; Aspirin; Blood Coagulation Tests; Gastritis; Gastrointestinal Hemorrhage; Humans; Liver | 1978 |
Prevention by bismuth subsalicylate of gastric mucosal lesions in response to noxious stimuli in rats.
Topics: Animals; Aspirin; Bismuth; Cold Temperature; Condiments; Ethanol; Female; Gastrointestinal Hemorrhag | 1978 |
[Drug-induced hemorrhagic gastritis in Africian blacks (preliminary study, apropos of 8 cases observed in Dakar].
Topics: Adult; Africa; Aspirin; Black People; Gastritis; Gastrointestinal Hemorrhage; Humans; Male; Middle A | 1977 |
[Complications of antithrombotic prophylaxis with acetylsalicylic acid (ASS) in polycythemia (author's transl)].
Topics: Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Heparin; Humans; Male; Polycythemia Vera; Thromb | 1978 |
The role of analgesic antirheumatic drugs in precipitating acute upper gastrointestinal bleeding.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans | 1977 |
A review of papers purporting to show a cause-and-effect relationship between aspirin ingestion and massive gastrointestinal haemorrhage.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hematemesis; Humans; Melena; Time Factors | 1977 |
Effects of sulphinpyrazone and aspirin on gastrointestinal blood loss in man.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Placebos; Sulfinpyrazone | 1978 |
Synergistic effect of vitamin C and aspirin on gastric lesions in the rat.
Topics: Animals; Ascorbic Acid; Aspirin; Dose-Response Relationship, Drug; Drug Synergism; Gastric Mucosa; G | 1978 |
Aspirin and gastrointestinal bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 1978 |
Aspirin and the stomach.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Stomach Ulcer | 1978 |
The lack of gastric tissue fibrinolysis in hemorrhagic gastritis in the rat.
Topics: Animals; Aspirin; Cold Temperature; Fibrinolysis; Gastritis; Gastrointestinal Hemorrhage; Male; Rats | 1979 |
[Importance of drug ingestion in the production of upper gastrointestinal hemorrhage in patients over 55 years of age].
Topics: Aged; Anti-Inflammatory Agents; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle A | 1979 |
Changes in platelet function and gastrointestinal bleeding following repeated administration of acetylsalicylic acid in the rat and the dog.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Collagen; Dogs; Gastrointestinal Hemorrhag | 1979 |
The economic potential and the role of aspirin and alcohol ingestion in relation to haematemesis and meleana.
Topics: Adult; Aged; Aspirin; Ethanol; Female; Gastrointestinal Hemorrhage; Hematemesis; Humans; Male; Melen | 1978 |
Aspirin's effect on the gastric mucosa.
Topics: Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans | 1979 |
Possible hazard of timed-release aspirin in a patient with pancreatic insufficiency.
Topics: Adult; Aspirin; Cystic Fibrosis; Delayed-Action Preparations; Gastrointestinal Hemorrhage; Humans; I | 1979 |
Drug-induced oesophageal injury.
Topics: Aspirin; Burns, Chemical; Codeine; Drug Combinations; Esophageal Diseases; Female; Gastrointestinal | 1979 |
Aspirin and gastrointestional bleeding. Interest of plasma salicylate determination.
Topics: Aspirin; Duodenal Diseases; Enteritis; Gastritis; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer | 1979 |
The role of microcirculation in iatrogenic gastrointestinal bleeding.
Topics: Aspirin; Cortisone; Digestive System; Gastrointestinal Hemorrhage; Homeostasis; Humans; Iatrogenic D | 1979 |
[Acute ulcerohemorrhagic gastritis].
Topics: Adolescent; Aspirin; Child; Child, Preschool; Gastritis; Gastrointestinal Hemorrhage; Humans; Male | 1978 |
[The effect of splenectomy on the platelet disorder of cirrhotics (author's transl)].
Topics: Aspirin; Blood Platelet Disorders; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Mal | 1979 |
Effects of cancer treatment on nutrition and gastrointestinal function.
Topics: Antineoplastic Agents; Aspirin; Digestive System; Dose-Response Relationship, Radiation; Gastrointes | 1979 |
[Neonatal hemorrhage due to maternal antiplatelet therapy].
Topics: Acute Disease; Aspirin; Dipyridamole; Female; Gastrointestinal Hemorrhage; Humans; Infant, Newborn; | 1979 |
[New technic for the determination of gastrointestinal tolerance by means of radioisotopes in rats].
Topics: Animals; Aspirin; Feces; Gastrointestinal Hemorrhage; Iron Radioisotopes; Methods; Rats | 1979 |
How aspirin and alcohol interact to accentuate GI bleeding.
Topics: Aspirin; Drug Interactions; Ethanol; Gastritis; Gastrointestinal Hemorrhage; Humans | 1979 |
[Value of endoscopy in the diagnosis of upper digestive tract hemorrhage].
Topics: Alcoholic Beverages; Aspirin; Critical Care; Duodenal Ulcer; Endoscopy; Esophageal Diseases; Gastroi | 1979 |
Diclofenac sodium (Voltarol): drug interactions and special studies.
Topics: Adult; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Blood Coagulation Factors; Blood Glucose; | 1979 |
[The effect of Voltaren on the gastrointestinal excretion of blood (author's transl)].
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Chromium Radioisotopes; Erythrocytes; Feces; Gastrointesti | 1975 |
Massive bleeding from the pharyngoesophageal diverticulum.
Topics: Aspirin; Diverticulum; Esophageal Diseases; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; | 1976 |
Role of bile acids in the pathogenesis of aspirin-induced gastric mucosal hemorrhage in rats.
Topics: Administration, Oral; Animals; Aspirin; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; D | 1975 |
[Gastric hemorrhage caused by acetylsalicylic acid--a comparison of soluble and buffered preparations].
Topics: Adult; Aspirin; Buffers; Gastrointestinal Hemorrhage; Humans; Middle Aged; Tablets, Enteric-Coated | 1975 |
[Prevention of digestive complications of aspirin].
Topics: Animals; Aspirin; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Humans; Necrosis; Rats; So | 1975 |
Parenteral aspirin produces and enhances gastric mucosal lesions and bleeding in rats.
Topics: Animals; Aspirin; Cold Temperature; Dose-Response Relationship, Drug; Gastric Mucosa; Gastrointestin | 1975 |
Drugs affecting platelet function tests: their effects on haemostasis and surgical bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Disorders; Blood Donors; Blood P | 1975 |
Proceedings: Inhibition of aspirin and taurocholic acid-induced gastric mucosal bleeding by prostaglandin 15(R)15 methyl-E2 methyl ester.
Topics: Animals; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Prostaglandins; Rats; Taurocholic Aci | 1975 |
Severe gastrointestinal hemorrhage and anemia after therapeutic doses of aspirin in normal children.
Topics: Adolescent; Anemia; Aspirin; Child; Child, Preschool; Female; Gastrointestinal Hemorrhage; Humans; I | 1976 |
[Serious complications of current treatments].
Topics: Acidosis; Adolescent; Aged; Alcoholism; Antihypertensive Agents; Aspirin; Diuretics; Drug-Related Si | 1975 |
Occult gastrointestinal bleeding due to aspirin: comparison of two compounds.
Topics: Aspirin; Chromium Radioisotopes; Erythrocytes; Gastrointestinal Hemorrhage; Humans; Melena; Occult B | 1976 |
Letter: Minimizing the incidence of ASA-induced occult gastrointestinal bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 1976 |
[Serum salicylates in gastrointestinal hemorrhage].
Topics: Acute Disease; Adolescent; Adult; Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Hematemesis; H | 1976 |
Effect of prostaglandin 15(R) 15 methyl-E2 methyl ester on aspirin and taurocholic acid-induced gastric mucosal haemorrhage in rats.
Topics: Animals; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Prostaglandins; Rats; Taurochol | 1976 |
Effects of L-glutamine on acetylsalicylic acid-induced gastric lesions in normal and cirrhotic rats.
Topics: Animals; Aspirin; Carbon Tetrachloride Poisoning; Gastrointestinal Hemorrhage; Glutamine; Intestinal | 1975 |
Aspirin and prophylaxis of thromboembolic complications in patients with substitute heart valves.
Topics: Acenocoumarol; Anticoagulants; Aspirin; Blindness; Drug Therapy, Combination; Female; Gastrointestin | 1976 |
Editorial: Less gastric bleeding from aspirin.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Tablets, Enteric-Coated | 1976 |
Gastric devascularization: an alternate approach to the surgical treatment of massive, diffuse hemorrhage from gastritis.
Topics: Adult; Age Factors; Alcoholism; Aspirin; Burns; Child, Preschool; Female; Gastrectomy; Gastritis; Ga | 1976 |
Drug-associated deaths of medical inpatients.
Topics: Adolescent; Adult; Aged; Aspirin; Azathioprine; Drug Therapy; Female; Florida; Gastrointestinal Hemo | 1976 |
Analgesics--the choice.
Topics: Acetaminophen; Aspirin; Gastrointestinal Hemorrhage; Humans; Pain | 1976 |
[The antithrombotic treatment and prevention of recurrence with acetylsalicylic acid in myocardial infarct].
Topics: Animals; Anticoagulants; Aspirin; Dogs; Drug Hypersensitivity; Gastrointestinal Hemorrhage; Humans; | 1976 |
Letter: Gastrotoxic effect of parenteral aspirin.
Topics: Animals; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Infusions, Parenteral; Rats | 1976 |
Editorial: Aspirin and the transmucosal potential difference.
Topics: Animals; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Membrane Potentials; Stomach | 1976 |
Gastrointestinal microbleeding in normal subjects receiving acetylsalicylic acid, placebo, and R-803, a new antiinflammatory agent, in a design balanced for residual effects.
Topics: Anti-Inflammatory Agents; Aspirin; Benzofurans; Chromium Radioisotopes; Feces; Gastrointestinal Hemo | 1976 |
Diagnosis and management of upper gastrointestinal hemorrhage in children.
Topics: Aspirin; Blood Transfusion; Child; Child, Preschool; Esophageal and Gastric Varices; Esophagitis, Pe | 1976 |
Upper gastrointestinal hemorrhage clinical, radiological and endoscopic correlation of 100 consecutive cases.
Topics: Adult; Aged; Aspirin; Duodenal Ulcer; Endoscopy; Esophageal Diseases; Ethanol; Female; Gastritis; Ga | 1976 |
The influence of aspirin on gastrointestinal microbleeding in dogs with gastric ulcers.
Topics: Administration, Oral; Animals; Aspirin; Dogs; Gastrointestinal Hemorrhage; Male; Stomach Ulcer | 1976 |
Gastric ulcer: natural history and treatment.
Topics: Adult; Aspirin; Australia; Boston; Carbenoxolone; Female; Gastrointestinal Hemorrhage; Glycyrrhiza; | 1976 |
Gastric damage by drugs and the role of the mucosal barrier.
Topics: Animals; Aspirin; Dogs; Ethanol; Gastric Mucins; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans | 1976 |
Are all aspirins alike?
Topics: Antacids; Aspirin; Buffers; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Intestinal Absorpti | 1976 |
Effect of aspirin on blood fibrinolysis, coagulation and their correlation to bleeding tendencies.
Topics: Aspirin; Blood Coagulation; Fibrinolysis; Gastrointestinal Hemorrhage; Humans | 1976 |
Interaction between heparin and acetylsalicylic acid on gastric mucosal and skin bleeding in humans.
Topics: Adult; Aspirin; Bleeding Time; Drug Interactions; Female; Gastric Mucosa; Gastrointestinal Hemorrhag | 1992 |
Seasonal fluctuations in acute upper gastrointestinal bleeding: lack of effect of nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Ulcer; Emergencies; Esophagitis; Gastriti | 1992 |
Effects of prior use of non-steroidal anti-inflammatory drugs on renal function and transfusion requirements after upper gastrointestinal haemorrhage.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Transfusion; Creati | 1992 |
Objective evidence of aspirin use in both ulcer and nonulcer upper and lower gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Gastro | 1992 |
Misuse of aspirin for abdominal discomfort.
Topics: Advertising; Aspirin; Contraindications; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer | 1991 |
Hemorrhaging heart patients.
Topics: Aspirin; Gastrointestinal Hemorrhage; Heart Diseases; Humans; Tablets, Enteric-Coated | 1992 |
[Digestive hemorrhage following gastroduodenal ulcers caused by non-steroidal anti-inflammatory agents].
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastrointe | 1991 |
Overt gastrointestinal bleeding in the course of chronic low-dose aspirin administration for secondary prevention of arterial occlusive disease.
Topics: Arterial Occlusive Diseases; Aspirin; Gastrointestinal Hemorrhage; Humans | 1991 |
Occult aspirin intake revealed by a bleeding colonic angiodysplasia.
Topics: Anemia; Aspirin; Colon; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Munchausen Syndrome; | 1991 |
[The duodenum and non-steroidal anti-inflammatory agents].
Topics: Adolescent; Adult; Aged; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Ulcer; | 1990 |
Overt gastrointestinal bleeding in the course of chronic low-dose aspirin administration for secondary prevention of arterial occlusive disease.
Topics: Aged; Arterial Occlusive Diseases; Aspirin; Female; Gastritis; Gastrointestinal Hemorrhage; Humans; | 1990 |
Value of a centralised approach in the management of haematemesis and melaena: experience in a district general hospital.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Femal | 1990 |
Studies of gastric ulcer disease by community-based gastroenterologists.
Topics: Abdominal Pain; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastroin | 1990 |
Rioprostil prevents aspirin-induced fecal blood loss in dogs. Correlation of Hemoquant (Hb) with endoscopic findings.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Dogs; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Gast | 1989 |
Aspirin use and chronic diseases: a cohort study of the elderly.
Topics: Aged; Aged, 80 and over; Aspirin; California; Cataract; Chronic Disease; Cohort Studies; Coronary Di | 1989 |
Ranitidine maintenance treatment of non-steroidal anti-inflammatory drug-induced duodenal ulceration.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Duodenal Ulcer; Du | 1989 |
Fatty acid changes in liver choline and ethanolamine glycerophospholipids in aspirin-treated rats fed linoleate, gamma-linolenate and fish oil.
Topics: Animals; Aspirin; Dietary Fats; Fatty Acids, Unsaturated; Fish Oils; gamma-Linolenic Acid; Gastroint | 1989 |
Acute effects of fever, fasting and aspirin on infant rat gastric mucosa.
Topics: Animals; Aspirin; Fasting; Fever; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Rats; Rats, Inb | 1989 |
[Bleeding of Meckel's diverticulum after ingestion of aspirin].
Topics: Adult; Aspirin; Gastrointestinal Hemorrhage; Humans; Intestine, Small; Male; Meckel Diverticulum | 1989 |
Intragastric capsaicin protects against aspirin-induced lesion formation and bleeding in the rat gastric mucosa.
Topics: Animals; Aspirin; Blood Pressure; Capsaicin; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Ma | 1989 |
Close arterial infusion of calcitonin gene-related peptide into the rat stomach inhibits aspirin- and ethanol-induced hemorrhagic damage.
Topics: Animals; Aspirin; Calcitonin Gene-Related Peptide; Ethanol; Female; Gastric Mucosa; Gastrointestinal | 1989 |
Incidence of NSAID-related, severe gastrointestinal bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; Prospective S | 1987 |
Ulcerations of the colon associated with naproxen and acetylsalicylic acid treatment.
Topics: Aspirin; Back Pain; Colonic Diseases; Colonoscopy; Female; Gastrointestinal Hemorrhage; Humans; Midd | 1986 |
[Upper digestive hemorrhage of iatrogenic cause].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Aspirin; Female; Gastrointestin | 1988 |
Prophylaxis of aspirin-induced gastric mucosal bleeding with ranitidine.
Topics: Adult; Aspirin; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Male; Ranitidine | 1988 |
Protective effect of gamma-linolenic acid on aspirin-induced gastric hemorrhage in rats.
Topics: Animals; Arachidonic Acids; Aspirin; Fatty Acids; Female; gamma-Linolenic Acid; Gastric Mucosa; Gast | 1987 |
Strategies for preventing aspirin-induced gastric bleeding.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cattle; Enprostil; Fatty Acids, Essential; Fatty Acids, | 1986 |
Misoprostol attenuates aspirin-induced changes in potential difference and associated damage in canine gastric mucosa.
Topics: Alprostadil; Animals; Anti-Ulcer Agents; Aspirin; DNA; Dogs; Dose-Response Relationship, Drug; Epith | 1987 |
Gastric mucosal protection by new aryl sulfhydryl drugs.
Topics: Animals; Aspirin; Chronic Disease; Dose-Response Relationship, Drug; Ethanol; Ethylmaleimide; Female | 1988 |
Major upper gastrointestinal tract bleeding. Relation to the use of aspirin and other nonnarcotic analgesics.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Aspirin; Drug Administration Schedule; Female; G | 1988 |
Intragastric accumulation of Evan's blue as a method for assessing aspirin-induced acute gastric mucosal injury in humans.
Topics: Adult; Aspirin; Azo Compounds; Capillary Permeability; DNA; Evans Blue; Female; Gastric Juice; Gastr | 1988 |
Gastric adaptation. Studies in humans during continuous aspirin administration.
Topics: Adaptation, Physiological; Adult; Aspirin; Cell Division; Gastric Mucosa; Gastrointestinal Contents; | 1988 |
Time-course study of gastric damages in rats by anti-inflammatory drugs using a gastroscope and its quantification.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Fenoprofen; Gastric Mucosa; Gastrointesti | 1988 |
[Drug-induced gastrointestinal hemorrhage. It is possible to reduce the occurrence?].
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gas | 1986 |
[Consumption of anti-inflammatory agents is not unusual in patients with acute upper gastrointestinal hemorrhage].
Topics: Acute Disease; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastroint | 1986 |
[Acetylsalicylic acid and gastric hemorrhage].
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 1986 |
Effect of cimetidine on aspirin-induced gastric hemorrhage in dogs.
Topics: Animals; Aspirin; Cimetidine; Dogs; Feces; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Hemo | 1986 |
[Acetylsalicylic acid].
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 1986 |
Piroxicam and gastrointestinal bleeding.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Drug Utilization; Female; Gastrointestinal Hemorrhage; Hosp | 1986 |
Anti-inflammatory drug intake and the risk of ulcer complications.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; | 1986 |
Drug-induced bleeding of gastric leiomyoma.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; | 1987 |
Reinforcement of bias in the medical literature: nonsteroidal anti-inflammatory drugs and the stomach--a case in point.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; Iatrogenic Di | 1987 |
Comparative studies on the gastrointestinal lesions caused by several nonsteroidal anti-inflammatory agents in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Feces; Gastric Muco | 1987 |
Is an acid pH medium required for the protective effect of sucralfate against mucosal injury?
Topics: Animals; Aspirin; Bile Acids and Salts; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; H | 1987 |
Aspirin and gastrointestinal haemorrhage: a methodologic assessment.
Topics: Aspirin; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Random Allocation; Research Desig | 1985 |
Differences in the haemorrhagic toxicity of aspirin between rats and mice.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Gentisates; Hydroxy | 1985 |
Prostaglandin and aspirin.
Topics: Aspirin; Dinoprostone; Gastrointestinal Hemorrhage; Humans; Prostaglandins E; Statistics as Topic | 1985 |
Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103).
Topics: Acetates; Acetic Acid; Aminopyrine; Animals; Anti-Ulcer Agents; Aspirin; Bethanechol Compounds; Cime | 1985 |
Reduction in gastric mucosal hemorrhage and ulceration with chronic high-level dosing of enteric-coated aspirin granules two and four times a day.
Topics: Adolescent; Adult; Aspirin; Drug Administration Schedule; Duodenum; Female; Gastric Mucosa; Gastroin | 1985 |
[Digestive hemorrhage caused by drugs].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Female; Gastrointestinal Hemorrhage; Hum | 1985 |
Gastrointestinal bleeding: a possible association with ibuprofen.
Topics: Acetaminophen; Aminopyrine; Analgesics; Anti-Inflammatory Agents; Aspirin; Benzyl Compounds; Child; | 1972 |
Pain in haemophilia.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemophilia A; Humans; Indomethacin; Male; Pain; Phenylbutazone | 1973 |
Pain in haemophilia.
Topics: Acetaminophen; Analgesics; Aspirin; Codeine; Cryotherapy; Gastrointestinal Hemorrhage; Headache; Hem | 1973 |
Letter: Aspirin and arteriolar responses to noradrenaline.
Topics: Animals; Aspirin; Chemotherapy, Cancer, Regional Perfusion; Femoral Artery; Gastrointestinal Hemorrh | 1974 |
Ascorbic-acid levels in leucocytes of patients with gastrointestinal haemorrhage.
Topics: Adult; Alcoholic Intoxication; Ascorbic Acid; Ascorbic Acid Deficiency; Aspirin; Blood Cell Count; C | 1968 |
Aspirin, vitamin-C deficiency, and gastric haemorrhage.
Topics: Aged; Ascorbic Acid Deficiency; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans | 1968 |
Aspirin, alcohol, and gastric haemorrhage.
Topics: Aspirin; Ethanol; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans | 1969 |
Aspirin, alcohol, and gastric haemorrhage.
Topics: Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Middle Aged; Stomach Diseases; Telangiectasis; | 1969 |
Faecal blood-loss after sodium acetylsalicylate taken with alcohol.
Topics: Aspirin; Drug Synergism; Ethanol; Gastrointestinal Hemorrhage; Hematemesis; Humans; Melena; Occult B | 1969 |
Gastrointestinal bleeding.
Topics: Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged | 1970 |
[The effect of various drugs in clinical use on thrombocyte functions].
Topics: Adolescent; Adult; Aged; Aminobenzoates; Aminocaproates; Arthritis, Rheumatoid; Aspirin; Blood Coagu | 1969 |
Aspirin disease and adverse effects.
Topics: Adult; Aspirin; Asthma; Blood Platelet Disorders; Female; Gastrointestinal Hemorrhage; Humans; Male; | 1971 |
[Abdomino-digestive complications from anticoagulants].
Topics: Abdominal Muscles; Anticoagulants; Aspirin; Drug Synergism; Gastrointestinal Hemorrhage; Hematoma; H | 1973 |
[Duodenal ulcer and accessory pancreatitis. Sever hemorrhage triggered off by contact with aspirin].
Topics: Aspirin; Duodenal Ulcer; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Pan | 1970 |
[The fate of 165 hemorrhagic ulcers treated in a special intensive care unit].
Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Emergencies; Esoph | 1973 |
[Digestive hemorrhages caused by drugs].
Topics: Anti-Inflammatory Agents; Anticoagulants; Aspirin; Drug-Related Side Effects and Adverse Reactions; | 1973 |
Pharmacological actions of a novel O-acetylsalicylic acid composition.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arylsulfonates; Aspirin; Cats; Dogs; Drug E | 1973 |
Aspirin and mucus.
Topics: Animals; Aspirin; Gastric Mucins; Gastric Mucosa; Gastrointestinal Hemorrhage; Hydrogen-Ion Concentr | 1968 |
[Analgesics in dentistry].
Topics: Acetanilides; Agranulocytosis; Analgesics; Anesthesia, Dental; Aspirin; Blood Coagulation; Caffeine; | 1972 |
New salicylates.
Topics: Animals; Arthritis, Rheumatoid; Aspirin; Diatrizoate; Gastrointestinal Hemorrhage; Humans; Platelet | 1972 |
Effect of pharmaceutical formulation on gastrointestinal bleeding from aspirin tablets.
Topics: Administration, Oral; Adult; Antacids; Aspirin; Buffers; Chromium Isotopes; Female; Gastric Acidity | 1972 |
The natural history of duodenal ulceration.
Topics: Aspirin; Duodenal Ulcer; Female; Gastric Acidity Determination; Gastric Juice; Gastrointestinal Hemo | 1972 |
[Undesired collateral effects of salicylates].
Topics: Anemia; Arthritis, Rheumatoid; Aspirin; Blood Coagulation Disorders; Dysautonomia, Familial; Gastroi | 1972 |
Effects of salicylates on the canine stomach: a morphological and histochemical study.
Topics: Administration, Oral; Animals; Aspirin; Autopsy; Autoradiography; Biopsy; Body Weight; Dogs; Epithel | 1972 |
[Acetylsalicylic acid preparations--gastrointestinal hemorrhage].
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 1972 |
[Nosologic borderlines of gastroduodenal ulcerous disease].
Topics: Aspirin; Diagnosis, Differential; Gastritis; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer; Pept | 1972 |
Abnormal aspirin metabolism in patients with cirrhosis and its possible relationship to bleeding in cirrhotics.
Topics: Adult; Animals; Aspirin; Esterases; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Hyd | 1972 |
Acute gastro-intestinal haemorrhage. Prognostic factors on a conservative regime.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aspirin; Australia; Child; Child, Preschool; Du | 1972 |
[Management of upper gastrointestinal bleeding. 2. Views of the specialist in internal medicine].
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Medical History Taking; Methods | 1972 |
[Value of the lymphoblastic transformation test in hemorrhagic gastritis caused by aspirin ingestion].
Topics: Aspirin; Gastritis; Gastrointestinal Hemorrhage; Humans; Lymphocyte Activation; Stomach | 1972 |
Gastric mucosal damage by anti-inflammatory drugs.
Topics: Absorption; Anti-Inflammatory Agents; Aspirin; Diffusion; Gastric Mucins; Gastric Mucosa; Gastritis; | 1972 |
Measurement of gastrointestinal blood loss in the rat: the effect of aspirn, phenylbutazone and seclazone.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Benzoxepins; Carbon Isotopes; Chromium Isotopes; Feces; | 1973 |
[Ulcers of the gastroduodenal tract due to drugs. Apropos of a personal experience].
Topics: Adrenal Cortex Hormones; Adult; Aged; Analgesics; Aspirin; Duodenal Ulcer; Female; Gastrointestinal | 1972 |
Development of aspirin hydrolase in fetal, newborn and adult tissues.
Topics: Abnormalities, Drug-Induced; Adenosine Diphosphate; Age Factors; Animals; Animals, Newborn; Aspirin; | 1973 |
Aspirin-induced gastrointestinal microbleeding in dogs.
Topics: Analysis of Variance; Animals; Aspirin; Body Weight; Dogs; Dose-Response Relationship, Drug; Feces; | 1973 |
[Intragastric acidity determination following administration of Alcacyl B1. A contribution on the etiology of gastrointestinal hemorrhages due to acetylsalicylic acid].
Topics: Aluminum Hydroxide; Aspirin; Calcium; Carbamates; Drug Combinations; Gastric Acidity Determination; | 1972 |
[Gastrointestinal blood loss in various iron deficiency anemias].
Topics: Anemia, Hypochromic; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; Melena | 1973 |
The management of upper gastro-intestinal tract haemorrhage.
Topics: Adolescent; Adult; Aged; Aortic Aneurysm; Aspirin; Carcinoma; Duodenal Ulcer; Esophageal and Gastric | 1973 |
Differential topography of acute erosive gastritis due to trauma or sepsis, ethanol and aspirin.
Topics: Abdominal Injuries; Acute Disease; Aspirin; Bacterial Infections; Ethanol; Gastritis; Gastrointestin | 1973 |
Aspirin-induced haemorrhage in gastric leiomyoma.
Topics: Adult; Aspirin; Gastrointestinal Hemorrhage; Humans; Leiomyoma; Male; Radiography; Stomach Neoplasms | 1973 |
Acute "stress" ulcers of the stomach: a review.
Topics: Acute Disease; Age Factors; Antacids; Aspirin; Bacteria; Gastric Juice; Gastric Mucosa; Gastrointest | 1973 |
Cancer and upper gastrointestinal tract hemorrhage. Benign causes of bleeding demonstrated by endoscopy.
Topics: Acute Disease; Adenocarcinoma; Aspirin; Chronic Disease; Endoscopy; Esophageal and Gastric Varices; | 1973 |
Gastrointestinal blood loss during prolonged aspirin administration.
Topics: Administration, Oral; Adult; Aspirin; Chromium Radioisotopes; Drug Tolerance; Female; Gastrointestin | 1973 |
The gastric mucosal response to acetylsalicylic acid in the ferret. An ultrastructural study.
Topics: Animals; Aspirin; Carnivora; Cytoplasm; Disease Susceptibility; Endoplasmic Reticulum; Epithelial Ce | 1973 |
Epidemiology and course of gastrointestinal haemorrhage in North-east Scotland.
Topics: Adult; Aged; Alcohol Drinking; Aspirin; Blood Group Antigens; Duodenal Ulcer; Female; Gastritis; Gas | 1973 |
Letter: Mechanism of aspirin-induced GI blood loss.
Topics: Aspirin; Blood Platelets; Gastrointestinal Hemorrhage; Humans; Platelet Adhesiveness | 1973 |
[Gastric and duodenal hemorrhage after drug administration].
Topics: Analgesics; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Chloramphenicol; Duodenal Diseases; G | 1973 |
Gastro-intestinal blood loss with sustained release aspirin.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Chromium Radioisotopes; Delayed-Action Prep | 1973 |
Personality factors in analgesic nephropathy.
Topics: Adult; Aged; Analgesics; Aspirin; Creatinine; Extraversion, Psychological; Female; Gastrointestinal | 1974 |
Observations on drug prescribing in rheumatoid arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Drug Prescriptions | 1974 |
Letter: Naproxen (naprosyn) and gastrointestinal haemorrhage.
Topics: Acetanilides; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Blood Transfusion; Female; Gastritis; | 1974 |
Disseminated intravascular coagulation after excision of giant hemangioma.
Topics: Adolescent; Afibrinogenemia; Anemia, Hemolytic, Congenital; Aspirin; Blood Platelet Disorders; Disse | 1974 |
[The effect of acetylsalicylic acid on the mucous membrane of the stomach].
Topics: Animals; Aspirin; Dogs; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Rats; Solubility | 1973 |
Aspirin use in patients with major upper gastrointestinal bleeding and peptic-ulcer disease. A report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center.
Topics: Adult; Aged; Aspirin; Boston; Drug Evaluation; Duodenal Ulcer; Female; Gastrointestinal Hemorrhage; | 1974 |
Editorial: The side effects of aspirin.
Topics: Aspirin; Drug Evaluation; Gastrointestinal Hemorrhage; Humans | 1974 |
Prevention of antiinflammatory drug-induced gastric lesions in rats by Abbott-29590.
Topics: Analgesics; Animals; Aspirin; Dose-Response Relationship, Drug; Drug Interactions; Gastric Juice; Ga | 1974 |
[Gastro-duodenal tolerance of some drugs with analgesic effect. Clinico-endoscopic considerations].
Topics: Analgesics; Anti-Inflammatory Agents; Antimalarials; Aspirin; Digestive System; Duodenal Ulcer; Esop | 1974 |
Pharmacology of a new non-steroidal anti-inflammatory agent 7-chloro-3,3a-dihydro-2-methyl-2H,9H-isoxazolo-(3,2-b)(1,3)-benzoxazin-9-one (W-2395).
Topics: Adjuvants, Immunologic; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoxazi | 1974 |
[Endoscopic diagnosis of acute medication (aspirin) ulcers of the duodenal bulb].
Topics: Acute Disease; Adult; Aspirin; Chronic Disease; Duodenal Ulcer; Endoscopy; Gastrointestinal Hemorrha | 1974 |
[Upper digestive hemorrhages due to gastritis or of unknown cause. (Apropos of 140 cases)].
Topics: Alcoholism; Aspirin; Endoscopy; Esophageal and Gastric Varices; Fiber Optic Technology; Gastrectomy; | 1973 |
Editorial: Aspirin and what else?
Topics: Aspirin; Drug Synergism; Gastrointestinal Hemorrhage; Hemostasis; Humans; Platelet Adhesiveness | 1974 |
Bleeding gastritis induced by long-term release aspirin.
Topics: Acetaminophen; Adult; Aspirin; Delayed-Action Preparations; Drug Evaluation; Female; Gastric Mucosa; | 1974 |
Aspirin--a dangerous drug?
Topics: Aspirin; Asthma; Drug Hypersensitivity; Gastrointestinal Hemorrhage; Humans; Legislation, Drug; Prot | 1974 |
Carbazochrome salicylate and its role in aspirin-induced gastric irritation in rats.
Topics: Animals; Aspirin; Drug Synergism; Gastric Mucosa; Gastrointestinal Hemorrhage; Hemostatics; Male; Me | 1974 |
Interaction of salicylic acid with adenosine and adenosine triphosphate: potential mechanism of intensifying aspirin-induced GI blood loss.
Topics: Adenosine; Adenosine Triphosphate; Aspirin; Chemical Phenomena; Chemistry; Drug Interactions; Gastro | 1974 |
Letter: Aspirin and G-I bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 1974 |
[The connection between upper gastro-intestinal hemorrhage and acetylsalicylic acid].
Topics: Administration, Oral; Adult; Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; Middl | 1974 |
Letter: Timed-release aspirin.
Topics: Aspirin; Delayed-Action Preparations; Gastrointestinal Hemorrhage; Humans | 1974 |
Gastrointestinal blood loss caused by tolmetin, aspirin, and indomethacin.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Benzoates; Chromium Radioisotopes; Diet; Female; Gastroint | 1974 |
Letter: Gastric irritation and bleeding after drug administration.
Topics: Animals; Aspirin; Caffeine; Ethanol; Gastroenteritis; Gastrointestinal Hemorrhage; Intubation, Gastr | 1974 |
Letter: Crushed aspirin tablets.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Powders; Tablets | 1974 |
[Induction of gastrointestinal hemorrhages in the rat by acetylsalicylic acid and acetylsalicylic acid-containing drugs].
Topics: Administration, Oral; Animals; Aspirin; Chromium Radioisotopes; Diarrhea; Drug Combinations; Erythro | 1974 |
[Salicylates and occult hemorrhages in the gastro-intestinal tract].
Topics: Animals; Aspirin; Benzidines; Drug Combinations; Drug Hypersensitivity; Feces; Gastrointestinal Hemo | 1974 |
[Recurrent gastric hemorrhage caused by salicylic acid].
Topics: Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Hematemesis; Humans; Male; Melena | 1974 |
Action of acetylsalicylic acid and glucagon on acid secretion mucosal blood flow, bleeding and net ionic efflux in the fundic pouch of pentagastrin-stimulated dogs.
Topics: Aminopyrine; Animals; Aspirin; Calcium; Chromium Radioisotopes; Dogs; Female; Gastric Juice; Gastric | 1974 |
[Etiopathogenesis of various hemorrhagic conditions in children].
Topics: Adolescent; Aspirin; Child; Drug Hypersensitivity; Female; Food Hypersensitivity; Gastrointestinal H | 1974 |
[Clinical significance of the so-called gastric mucous barrier].
Topics: Animals; Aspirin; Atropine; Dogs; Ethanol; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; H | 1974 |
Comparative studies of the effect of aspirin and sodium salicylate on the frequency of gastrointestinal bleedings.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Aged; Aminopyrine; Arthritis, Rheumatoid; Aspirin; Bip | 1968 |
Survey of haemorrhagic erosive gastritis.
Topics: ABO Blood-Group System; Achlorhydria; Acute Disease; Adult; Aged; Aspirin; Autoantibodies; Female; F | 1968 |
Influence of achlorhydria on aspirin-induced occult gastrointestinal blood loss: studies in Addisonian pernicious anaemia.
Topics: Achlorhydria; Adult; Aged; Anemia, Pernicious; Aspirin; Bone Marrow Examination; Female; Fluorescent | 1970 |
Aspirin--Rosetta Stone of gastrointestinal hemorrhage: a point of view.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Medical History Taking; Prospective Studies | 1968 |
Gastrointestinal disturbances with aspirin.
Topics: Animals; Aspirin; Dogs; Gastrointestinal Hemorrhage; Heartburn; Humans; Tablets, Enteric-Coated | 1965 |
[Death-treatening hemorrhages from the digestive tract following aspirin administration].
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 1965 |
[Nil nocere. Gastrointestinal hemorrhage caused by salicylates?].
Topics: Adult; Aged; Aspirin; Feces; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Occult | 1965 |
Heidenhain pouch bleeding due to oral salicylates.
Topics: Animals; Aspirin; Chromium Isotopes; Dogs; Gastric Mucosa; Gastrointestinal Hemorrhage; Salicylates | 1966 |
Gastric mucosal injury by aspirin.
Topics: Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Stomach Diseases | 1966 |
ABO blood groups in gastric bleeding.
Topics: ABO Blood-Group System; Adult; Aspirin; Blood Group Antigens; Duodenal Ulcer; Female; Gastric Mucosa | 1966 |
Gastro-intestinal bleeding: a comparison of mefenamic acid and aspirin.
Topics: Anti-Inflammatory Agents; Aspirin; Feces; Gastrointestinal Hemorrhage; Humans; Mefenamic Acid; ortho | 1967 |
Relationship between aspirin taking and gastroduodenal haemorrhage.
Topics: Adolescent; Adult; Aged; Aspirin; Child; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle A | 1967 |
Headache nostrums and chronic illness.
Topics: Analgesics; Aspirin; Chronic Disease; Gastrointestinal Hemorrhage; Headache; Kidney Diseases; Monoam | 1966 |
The acute rectal toxicity of acetylsalicylic acid.
Topics: Adrenal Glands; Animals; Aspirin; Ataxia; Body Weight; Brain; Coma; Diarrhea; Diuresis; Dyspnea; Fee | 1966 |
Aspirin and gastric bleeding.
Topics: Acetaminophen; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer | 1967 |
Changing concepts in the surgical management of hemorrhagic gastritis.
Topics: Aspirin; Female; Gastritis; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Pylorus; Vagotom | 1967 |
Aspirin and gastric bleeding.
Topics: Aspirin; Bicarbonates; Gastrointestinal Hemorrhage; Humans; Sodium | 1967 |
[On the problem of the occurrence of occult bleeding following treatment with salicylates. 2].
Topics: Animals; Aspirin; Biphenyl Compounds; Feces; Female; Gastrointestinal Hemorrhage; Guinea Pigs; Helmi | 1966 |
[Treatment with aspirin and sodium salicylate and gastrointestinal hemorrhage].
Topics: Aspirin; Biphenyl Compounds; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Sodium Salicylate | 1967 |
Analgesic habits of 500 veterans: incidence and complications of abuse.
Topics: Adult; Aged; Analgesics; Anemia; Arthritis; Aspirin; Caffeine; Canada; Codeine; Gastrointestinal Hem | 1968 |
[Gastrointestinal bleeding and salicylates. A comparative study between acetylsalicylic acid and salicylsalicylic acid].
Topics: Adult; Aged; Aspirin; Feces; Female; Gastrointestinal Hemorrhage; Humans; Male; Melena; Middle Aged; | 1968 |
Diaryloxazole and diarylthiazolealkanoic acids: two novel series of non-steroidal anti-inflammatory agents.
Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Aspirin; Biological Assay; Carrageenan; Edema; Gastric | 1968 |
[Official decisions on certain drugs].
Topics: Aspirin; Dentistry; Gastrointestinal Hemorrhage; Phenacetin | 1967 |
Lesions associated with gastroduodenal haemorrhage, in relation to aspirin intake.
Topics: Adult; Aged; Aspirin; Duodenal Ulcer; Gastrointestinal Hemorrhage; Gastroscopy; Hematemesis; Humans; | 1968 |
Aspirin and gastrointestinal bleeding.
Topics: Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Humans | 1968 |
[Drug induced gastrointestinal bleeding].
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Prednisone | 1968 |
Evaluation of gastric acid as a factor in drug-induced gastric hemorrhage in the rat.
Topics: Animals; Aspirin; Gastric Juice; Gastrointestinal Hemorrhage; Glycine; Hexoses; Histamine; Phenylbut | 1969 |
Gastric mucosal hemorrhage in dogs. Effects of acid, aspirin, and alcohol.
Topics: Acids; Animals; Aspirin; Bethanechol Compounds; Buffers; Dogs; Ethanol; Gastric Acidity Determinatio | 1969 |
Aspirin and gastrointestinal bleeding.
Topics: Aspirin; Blood Coagulation Tests; DNA; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Hum | 1969 |
Gastrointestinal bleeding and aspirin.
Topics: Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Telangiectasia, Hereditary Hemorrhagic | 1969 |
Net ion flux and histopathologic changes induced by acute gastric dilatation: studies on an in vivo model.
Topics: Animals; Aspirin; Dilatation; Extracellular Space; Gastric Mucosa; Gastrointestinal Hemorrhage; Hydr | 1968 |
Gastrointestinal hemorrhage and aspirin.
Topics: Aspirin; Child, Preschool; Gastrointestinal Hemorrhage; Humans; Male | 1969 |
Aspirin and gastrointestinal bleeding. An opinion.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 1969 |
[Procedure to follow in case of severe hematemesis].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aspirin; Blood Transfusion; Blood Volume Determin | 1969 |
Gastrointestinal haemorrhage gastric ulcer, and aspirin abuse.
Topics: Adult; Age Factors; Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; P | 1969 |
Relationship between pH and absorption of acetylsalicylic acid from the stomach.
Topics: Absorption; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Hydrogen-Ion Concentration | 1969 |
Discussion on clinical trials of the fenamates.
Topics: Analgesia; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Central Nervous System; Flufena | 1966 |
Comparison of flufenamic acid with aspirin and paracetamol in terms of gastrointestinal blood loss.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chromium Isotopes; Fe | 1966 |
Failure of intravenous aspirin to increase gastrointestinal blood loss.
Topics: Adult; Aspirin; Chromium Isotopes; Erythrocytes; Feces; Gastric Juice; Gastrointestinal Hemorrhage; | 1969 |
Aspirin gastritis examined with intragastric photography.
Topics: Acetaminophen; Adult; Antacids; Aspirin; Buffers; Drug Hypersensitivity; Drug Synergism; Female; Gas | 1969 |
Biopharmaceutical aspects of aspirin-induced gastrointestinal blood loss in man.
Topics: Adolescent; Adult; Aspirin; Biopharmaceutics; Buffers; Chromium Isotopes; Drug Compounding; Female; | 1969 |
Gastro-intestinal bleeding: the role of vitamin C.
Topics: Ascorbic Acid Deficiency; Aspirin; Feeding Behavior; Gastrointestinal Hemorrhage; Hernia, Diaphragma | 1969 |
Effect of aspirin upon gastrointestinal blood loss in pernicious anaemia.
Topics: Achlorhydria; Anemia, Pernicious; Aspirin; Chromium Isotopes; Gastric Juice; Gastrointestinal Hemorr | 1969 |
Gastroscopic findings and fecal blood loss following aspirin administration.
Topics: ABO Blood-Group System; Adult; Aspirin; Blood Group Antigens; Chromium Isotopes; Erythrocytes; Feces | 1969 |
[Complications in the gastrointestinal tract during antirheumatic therapy].
Topics: Adult; Aspirin; Female; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Male; Middle | 1968 |
Problems in the management of massive hemorrhage from the esophagogastrointestinal tract.
Topics: Aged; Angiography; Aspirin; Cineradiography; Diverticulum, Colon; Endoscopy; Esophageal and Gastric | 1970 |
[Iatrogenic hemorrhage].
Topics: Anticoagulants; Aspirin; Drug-Related Side Effects and Adverse Reactions; Gastrointestinal Hemorrhag | 1968 |
Gastric absorption and distribution of acetylsalicylic acid and other acidic compounds in the rat.
Topics: Acetates; Acids; Animals; Aspirin; Autoradiography; Barbiturates; Benzoates; Carbon Isotopes; Chroma | 1970 |
Role of occult blood loss in anaemia after partial gastrectomy.
Topics: Adult; Aged; Anemia, Hypochromic; Aspirin; Female; Gastritis; Gastrointestinal Hemorrhage; Hemoglobi | 1970 |
Unusual causes of occult bleeding from the gastrointestinal tract.
Topics: Adolescent; Adult; Aged; Anemia; Aspirin; Child; Diagnosis, Differential; Esophagitis, Peptic; Femal | 1970 |
[Digestive hemorrhage due to drugs (except anticoagulants). 80 cases].
Topics: Adult; Aged; Aspirin; Cortisone; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Phe | 1970 |
Susceptibility to aspirin bleeding.
Topics: Alcohols; Anemia, Hypochromic; Aspirin; Gastric Juice; Gastric Mucosa; Gastrointestinal Hemorrhage; | 1970 |
Comparison of gross and microscopic gastric lesions produced in rats after single doses of aspirin and 2-deoxyglucose.
Topics: Administration, Oral; Animals; Aspirin; Gastric Mucosa; Gastrointestinal Hemorrhage; Hexoses; Hydroc | 1970 |
Gastrointestinal haemorrhage, gastric ulcer and aspirin.
Topics: Acute Disease; Adult; Age Factors; Aged; Aspirin; Australia; Diagnosis, Differential; Female; Gastro | 1970 |
Aspirin and gastrointestinal bleeding.
Topics: Aspirin; Chronic Disease; Female; Gastrointestinal Hemorrhage; Humans; Melena; Stomach Ulcer | 1970 |
[Apropos of 135 cases of massive gastroduodenal hemorrhage (portal hypertension excluded)].
Topics: Adult; Aged; Anticoagulants; Aspirin; Cortisone; Endoscopy; Female; Gastritis; Gastrointestinal Hemo | 1968 |
Susceptibility to aspirin bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Occult Blood | 1970 |
Aspirin and alternatives.
Topics: Adult; Analgesics; Anti-Inflammatory Agents; Aspirin; Fever; Gastrointestinal Hemorrhage; Humans; In | 1970 |
Susceptibility of aspirin bleeding.
Topics: Acute Disease; Aspirin; Gastrointestinal Hemorrhage; Humans | 1970 |
[Acetylsalicylic acid and serious stomach hemorrhage].
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 1969 |
Coagulation defects in undiagnosed recurrent gastrointestinal bleeding.
Topics: Adult; Aged; Aspirin; Blood Coagulation Disorders; Blood Coagulation Factors; Blood Coagulation Test | 1970 |
Susceptibility to aspirin bleeding.
Topics: Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; Substance-Related Disorders | 1970 |
Arthritis, aspirin, and coma.
Topics: Arthritis, Juvenile; Aspirin; Brain Edema; Chemical and Drug Induced Liver Injury; Child, Preschool; | 1970 |
[Aspirin, gastrointestinal hemorrhage and platelets].
Topics: Animals; Aspirin; Blood Platelets; Gastrointestinal Hemorrhage; Hemostasis; Humans; Platelet Adhesiv | 1969 |
A safe aspirin preparation.
Topics: Acetaminophen; Aged; Arthritis; Aspirin; Female; Gastrointestinal Hemorrhage; Hemoglobinometry; Huma | 1970 |
Aspirin-induced occult gastrointestinal blood loss. Local versus systemic effects.
Topics: Administration, Oral; Adult; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Injections, Intra | 1970 |
Investigation of the carrageenin-induced rat paw edema assay and correlation between anti-inflammatory activity and gastric hemorrhage production in the rat.
Topics: Adrenalectomy; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Croton Oil; Edem | 1970 |
[Effects of aspirin and salicylates on the gastric mucosa].
Topics: Administration, Oral; Adolescent; Adult; Aspirin; Edema; Female; Gastric Mucosa; Gastritis; Gastroin | 1970 |
Hemorrhagic gastritis. Importance of associated chronic gastritis.
Topics: Acute Disease; Alcoholism; Aspirin; Atrophy; Biopsy; Chronic Disease; Gastric Mucosa; Gastritis; Gas | 1971 |
Aspirin and gastric hemorrhage.
Topics: Aspirin; Blood Platelet Disorders; Diagnosis, Differential; Gastric Mucosa; Gastritis; Gastrointesti | 1971 |
[Gastroduodenal hemorrhages caused by aspirin].
Topics: Adult; Aspirin; Duodenum; Female; Gastrointestinal Hemorrhage; Humans; Male; Stomach | 1970 |
[Latent gastrointestinal bleeding during treatment with prednisolone and aspirin (study with radioactive chromium)].
Topics: Adult; Aged; Aspirin; Chromium Isotopes; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle A | 1970 |
Drug therapy. XII. Aspirin, what's new?
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans | 1971 |
Assessment of drug-induced occult bleeding.
Topics: Adult; Aged; Aspirin; Chromium Isotopes; Erythrocytes; Female; Gastrointestinal Hemorrhage; Humans; | 1971 |
Comparison of gastric toxicity of acetylsalicylic acid with route of administration in the rat.
Topics: Animals; Aspirin; Disease Models, Animal; Gastric Acidity Determination; Gastric Juice; Gastric Muco | 1971 |
[Our experience with drug-induced digestive hemorrhage and erosive gastritis].
Topics: Adolescent; Adult; Aged; Analgesics; Aspirin; Child; Corticosterone; Female; Gastritis; Gastrointest | 1971 |
New support for an old stand-by.
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Thromboembolism | 1971 |
[Acetylsalicylic acid: an old drug from a current viewpoint].
Topics: Anhydrides; Animals; Antibodies, Anti-Idiotypic; Antibody Formation; Aspirin; Blood Platelets; Blood | 1971 |
Effect of aspirin and related compounds on the fine structure of mouse gastric mucosa.
Topics: Acetates; Administration, Oral; Animals; Aspirin; Benzoates; Carboxylic Acids; Epithelium; Female; G | 1971 |
New method for evaluating topical action of substances on gastric mucosa.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cats; Female; Gastric Juice; Gastric Mucosa; Gastrointes | 1971 |
Mortality following emergency partial gastrectomy for gastro-duodenal haemorrhage.
Topics: Age Factors; Aged; Aspirin; Blood Transfusion; Emergencies; Female; Gastrectomy; Gastrointestinal He | 1971 |
[Salicylate preparations and the risk of gastric bleeding].
Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Stomach | 1971 |
The disappearance of acetylsalicylic acid (ASA) in aqueous solution from the cat stomach and its influence on the transmucosal ion transport in the innervated non-secreting stomach.
Topics: Animals; Aspirin; Cats; Chlorides; Gastric Juice; Gastric Mucosa; Gastrointestinal Hemorrhage; Hydro | 1971 |
Gastric bleeding and aspirin.
Topics: Aged; Aspirin; Gastrointestinal Hemorrhage; Humans; Male | 1971 |
[Digestive disorders from drug origin. I. Gastrointestinal lesions].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticoagulants; Aspirin; C | 1971 |
Aspirin and alcohol in gastrointestinal haemorrhage.
Topics: Aspirin; Drug Synergism; Duodenal Ulcer; Esophageal and Gastric Varices; Ethanol; Female; Gastritis; | 1971 |
Assessment of drug-induced gastric bleeding.
Topics: Anti-Inflammatory Agents; Aspirin; Choline; Chromium Isotopes; Erythrocytes; Feces; Gastrointestinal | 1971 |
Effects of route of administration on the production of gastric hemorrhage in the rat by aspirin and sodium salicylate.
Topics: Administration, Oral; Animals; Aspirin; Colon; Fasting; Gastric Mucosa; Gastrointestinal Hemorrhage; | 1971 |
The use and misuse of aspirin: a contemporary problem.
Topics: Adult; Aged; Analgesics; Anemia, Hypochromic; Aspirin; Blood Coagulation; Blood Platelet Disorders; | 1970 |
[Congenital factor 13 deficiency: severe abdominal hemorrhage after combined antiinflammatory therapy].
Topics: Appendectomy; Appendicitis; Aspirin; Blood Coagulation Disorders; Blood Platelets; Blood Transfusion | 1971 |
[Aspirin and digestive bleeding (new facts in the light of fibrogastroscopy)].
Topics: Aspirin; Fiber Optic Technology; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Optics and Photon | 1971 |
Haemorrhagic diathesis in children caused by acetylsalicylic acid and other analgesics.
Topics: Aminopyrine; Aspirin; Blood Platelet Disorders; Child; Gastrointestinal Hemorrhage; Hemorrhagic Diso | 1971 |
[Digestive hemorrhages due to salicylates].
Topics: Aspirin; Gastrointestinal Hemorrhage; Gastroscopy | 1970 |
Aspirin, platelets, and bleeding.
Topics: Adenine Nucleotides; Animals; Aspirin; Blood Coagulation; Blood Platelets; Gastrointestinal Hemorrha | 1969 |