Page last updated: 2024-10-23

aspirin and Gangrene

aspirin has been researched along with Gangrene in 24 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Gangrene: Death and putrefaction of tissue usually due to a loss of blood supply.

Research Excerpts

ExcerptRelevanceReference
"A patient who had small cell lung cancer complicated by symmetrical peripheral gangrene, secondary to spontaneous platelet aggregation, improved dramatically after starting aspirin treatment."7.68Digital gangrene in small cell lung cancer: response to aspirin treatment. ( Arrowsmith, JE; Bevan, DH; Cummin, AR; Nanson, EM; Woodhead, MA, 1991)
" centers, 231 male diabetic patients who had either a recent amputation for gangrene (N = 207) or active gangrene (N = 24) were randomly assigned to a group which received aspirin (325 mg t."5.05V.A. Cooperative Study on antiplatelet agents in diabetic patients after amputation for gangrene: III. Definitions and review of design and baseline characteristics. ( Abraira, C; Anderson, JW; Bingham, SF; Colwell, JA; Kwaan, HC, 1985)
"To evaluate whether long-term anticoagulation with low-molecular-weight heparin (LMWH) and warfarin is beneficial for treating the inflammation and symptoms associated with TAO."4.02Outcomes of Anticoagulant Therapy with Low-Molecular-Weight Heparin (LMWH) and Warfarin for Thromboangiitis Obliterans (TAO). ( Gao, J; Huang, L; Wang, J, 2021)
"A patient who had small cell lung cancer complicated by symmetrical peripheral gangrene, secondary to spontaneous platelet aggregation, improved dramatically after starting aspirin treatment."3.68Digital gangrene in small cell lung cancer: response to aspirin treatment. ( Arrowsmith, JE; Bevan, DH; Cummin, AR; Nanson, EM; Woodhead, MA, 1991)
"Thirty-five patients with gangrene or pregangrene of the feed associated with palpable peripheral pulses have been treated with the platelet suppressive drugs aspirin and dipyridamole."3.66Gangrene of the toes with palpable peripheral pulses. ( Chatterjee, DK; Greaney, M; Morris-Jones, W; Preston, FE, 1981)
"Erythromelalgia was localized in the forefoot sole and toes in 28, the fingertips in 9, the handpalm in 2."2.39Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia. ( Lindemans, J; Michiels, JJ; van Genderen, PJ; van Vliet, HH, 1996)
"Infants with incomplete and atypical Kawasaki disease are prone to intravenous immunoglobulin treatment failure and are at risk for the development of coronary artery aneurysms."1.34Incomplete and atypical Kawasaki disease in a young infant: severe, recalcitrant disease responsive to infliximab. ( O'connor, MJ; Saulsbury, FT, 2007)
"We report a 1-month-old infant with Kawasaki disease and peripheral gangrene."1.33Infantile Kawasaki disease and peripheral gangrene. ( Durall, AL; Mullett, CJ; Phillips, JR; Weisse, ME, 2006)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199013 (54.17)18.7374
1990's4 (16.67)18.2507
2000's2 (8.33)29.6817
2010's3 (12.50)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Bolaman, AZ1
Yavaşoǧlu, İ1
Gao, J1
Huang, L1
Wang, J1
Nkeck, JR1
Endomba, FTA1
Ndoadoumgue, AL1
Kalbassou, FB1
Misra, DP1
Chowdhury, AC1
Lal, H1
Mohindra, N1
Agarwal, V1
Krishnamurthy, S1
Jagadeesh, A1
Chandrasekaran, V1
Mahadevan, S1
Rajesh, NG1
TUFFANELLI, DL1
DUBOIS, EL1
Durall, AL1
Phillips, JR1
Weisse, ME1
Mullett, CJ1
O'connor, MJ1
Saulsbury, FT1
Heidrich, H1
Branson, HE1
Endo, Y1
Fagin, AR1
Schlutz, M1
Colwell, JA3
Bingham, SF3
Abraira, C2
Anderson, JW2
Kwaan, HC2
Preston, FE3
Chen, WY1
Lee, FN1
Hsieh, BS1
Yen, TS1
Chou, JH1
Morris-Jones, W1
Greaney, M1
Chatterjee, DK1
Johansen, K1
Hansen, ST1
Michiels, JJ1
van Genderen, PJ1
Lindemans, J1
van Vliet, HH1
Tanaka, T1
Takei, M1
Fukuta, Y1
Higashino, R1
Fukuda, Y1
Nomura, Y1
Ito, S1
Tamaki, H1
Kurimoto, T1
Suzuki, Y1
Amblard, P1
Lèques, B1
Seigneurin, D1
Verdaguer, S1
Reymond, JL1
Miller, JJ1
Fries, JF1
Arrowsmith, JE1
Woodhead, MA1
Bevan, DH1
Nanson, EM1
Cummin, AR1
Emmanuel, IG1
Winfield, DA1
Malia, RG1
Fitzgerald, DE1
Butterfield, WJ1

Reviews

4 reviews available for aspirin and Gangrene

ArticleYear
Gangrene in Takayasu's arteritis: a report of two cases and review of literature.
    Rheumatology international, 2016, Volume: 36, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Amputation, Surgical; Anticoagulants; Aspirin; Critical Illness

2016
[Peripheral arterial occlusions. Principles, possibilities and limits of conservative therapy].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1981, Apr-10, Volume: 57, Issue:10

    Topics: Ancrod; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Cardiomyopathies; Dextrans; Digitalis

1981
Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Adult; Aged; Aspirin; Busulfan; Double-Blind Method; Erythromelalgia; Female; Gangrene; Hemorrhage;

1996
VA cooperative study on antiplatelet agents in diabetic patients after amputation for gangrene. IV. Issues in design, interpretation, and analysis.
    Haemostasis, 1986, Volume: 16, Issue:6

    Topics: Amputation, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic;

1986

Trials

3 trials available for aspirin and Gangrene

ArticleYear
V.A. Cooperative Study on antiplatelet agents in diabetic patients after amputation for gangrene: I. Design, methods, and baseline characteristics.
    Controlled clinical trials, 1984, Volume: 5, Issue:2

    Topics: Amputation, Surgical; Aspirin; Clinical Trials as Topic; Diabetic Angiopathies; Dipyridamole; Epopro

1984
VA cooperative study on antiplatelet agents in diabetic patients after amputation for gangrene. IV. Issues in design, interpretation, and analysis.
    Haemostasis, 1986, Volume: 16, Issue:6

    Topics: Amputation, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic;

1986
V.A. Cooperative Study on antiplatelet agents in diabetic patients after amputation for gangrene: III. Definitions and review of design and baseline characteristics.
    Hormone and metabolic research. Supplement series, 1985, Volume: 15

    Topics: Amputation, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic;

1985

Other Studies

18 other studies available for aspirin and Gangrene

ArticleYear
Limb gangrene: The first sign of essential thrombocythemia.
    The Indian journal of medical research, 2020, Volume: 151, Issue:4

    Topics: Aged, 80 and over; Amputation, Surgical; Aspirin; Female; Gangrene; Humans; Hydroxyurea; Leg; Platel

2020
Outcomes of Anticoagulant Therapy with Low-Molecular-Weight Heparin (LMWH) and Warfarin for Thromboangiitis Obliterans (TAO).
    Current vascular pharmacology, 2021, Volume: 19, Issue:6

    Topics: Anticoagulants; Aspirin; C-Reactive Protein; Gangrene; Heparin, Low-Molecular-Weight; Humans; Inflam

2021
Gangrene of All Digits and Toes Attributable to Systemic Lupus Erythematosus With Negative Antiphospholipid Antibodies.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2019, Volume: 25, Issue:6

    Topics: Adult; Amputation, Surgical; Antibodies, Antiphospholipid; Aspirin; Female; Fingers; Follow-Up Studi

2019
Haemolytic uraemic syndrome with peripheral gangrene and Kawasaki disease in a 15-month-old child.
    Paediatrics and international child health, 2017, Volume: 37, Issue:1

    Topics: Abscess; Anti-Inflammatory Agents; Aspirin; Buttocks; Gangrene; Hemolytic-Uremic Syndrome; Humans; I

2017
CUTANEOUS MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUS.
    Archives of dermatology, 1964, Volume: 90

    Topics: Adrenal Cortex Hormones; Alopecia; Anti-Bacterial Agents; Antimalarials; Aspirin; Blister; Drug Erup

1964
Infantile Kawasaki disease and peripheral gangrene.
    The Journal of pediatrics, 2006, Volume: 149, Issue:1

    Topics: Abciximab; Amputation, Surgical; Anti-Bacterial Agents; Antibodies, Monoclonal; Anticoagulants; Anti

2006
Incomplete and atypical Kawasaki disease in a young infant: severe, recalcitrant disease responsive to infliximab.
    Clinical pediatrics, 2007, Volume: 46, Issue:4

    Topics: Acute Disease; Anti-Inflammatory Agents; Antibodies, Monoclonal; Aspirin; Coronary Aneurysm; Gangren

2007
Heritable alpha 2-macroglobulin deficiency in a patient with arterial thrombosis: alpha 2-macroglobulin deficiency Irvine.
    Journal of the National Medical Association, 1984, Volume: 76, Issue:11

    Topics: alpha-Macroglobulins; Arteriosclerosis; Aspirin; Dipyridamole; Female; Gangrene; Humans; Immunoelect

1984
Aspirin, prostaglandins, and peripheral gangrene.
    The American journal of medicine, 1983, Jun-14, Volume: 74, Issue:6A

    Topics: Adult; Aged; Aspirin; Blood Platelets; Female; Gangrene; Humans; Male; Middle Aged; Platelet Aggrega

1983
Studies on platelet aggregation and antiplatelet therapy in blackfoot disease.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1981, Volume: 80, Issue:9

    Topics: Adult; Aged; Aspirin; Dipyridamole; Female; Foot Diseases; Gangrene; Humans; Male; Middle Aged; Plat

1981
Gangrene of the toes with palpable peripheral pulses.
    Annals of surgery, 1981, Volume: 193, Issue:4

    Topics: Aged; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Gangrene; Humans; Ischemia; Male; Mi

1981
Symmetrical peripheral gangrene (purpura fulminans) complicating pneumococcal sepsis.
    American journal of surgery, 1993, Volume: 165, Issue:5

    Topics: Adrenal Cortex Hormones; Amputation, Surgical; Aspirin; Debridement; Dextrans; Dopamine; Fingers; Fo

1993
Arachidonic acid-induced hind limb gangrene: a new experimental rat model of peripheral vascular disease.
    Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:3

    Topics: Animals; Arachidonic Acid; Aspirin; Disease Models, Animal; Disease Progression; Drug Evaluation, Pr

1999
[Cutaneous symptoms of thrombocytemia (author's transl)].
    Annales de dermatologie et de venereologie, 1977, Volume: 104, Issue:2

    Topics: Adult; Aged; Aspirin; Female; Gangrene; Humans; Male; Middle Aged; Skin Diseases; Skin Ulcer; Thromb

1977
Simultaneous vasculitis in a mother and newborn infant.
    The Journal of pediatrics, 1975, Volume: 87, Issue:3

    Topics: Adult; Arthritis; Aspirin; Female; Gangrene; Gentamicins; Heparin; Humans; Infant, Newborn; Infant,

1975
Digital gangrene in small cell lung cancer: response to aspirin treatment.
    Thorax, 1991, Volume: 46, Issue:1

    Topics: Aspirin; Blood Platelet Disorders; Carcinoma, Small Cell; Fingers; Gangrene; Humans; Lung Neoplasms;

1991
Essential thrombocythaemia and peripheral gangrene.
    British medical journal, 1974, Aug-31, Volume: 3, Issue:5930

    Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Cell Count; Collagen; Gangrene; Humans; Male; Middle Ag

1974
A case of increased platelet anti-heparin factor in a patient with Raynaud's phenomena and gangrene, treated by aspirin.
    Angiology, 1969, Volume: 20, Issue:6

    Topics: Aspirin; Blood Platelets; Fingers; Gangrene; Heparin; Humans; Male; Middle Aged; Plethysmography; Ra

1969