Page last updated: 2024-10-23

aspirin and Gallstones

aspirin has been researched along with Gallstones in 6 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Gallstones: Solid crystalline precipitates in the BILIARY TRACT, usually formed in the GALLBLADDER, resulting in the condition of CHOLELITHIASIS. Gallstones, derived from the BILE, consist mainly of calcium, cholesterol, or bilirubin.

Research Excerpts

ExcerptRelevanceReference
" However, the effect of nonsteroidal anti-inflammatory drugs, such as aspirin, on biliary tract cancer has not been well studied."7.73Aspirin use and risk of biliary tract cancer: a population-based study in Shanghai, China. ( Deng, J; Fraumeni, JF; Gao, YT; Han, TQ; Hsing, AW; Liu, E; Rashid, A; Sakoda, LC; Shen, MC; Wang, BS; Zhang, BH, 2005)
" However, the effect of nonsteroidal anti-inflammatory drugs, such as aspirin, on biliary tract cancer has not been well studied."3.73Aspirin use and risk of biliary tract cancer: a population-based study in Shanghai, China. ( Deng, J; Fraumeni, JF; Gao, YT; Han, TQ; Hsing, AW; Liu, E; Rashid, A; Sakoda, LC; Shen, MC; Wang, BS; Zhang, BH, 2005)
"Aspirin, which has been shown to reduce the local production of gall bladder mucins (mucosal or parietal factors of gallstone formation) in animal experimental models, does not appear to reduce the risk of symptomatic gallstones disease when tested alone."2.48Limits and perspective of oral therapy with statins and aspirin for the prevention of symptomatic cholesterol gallstone disease. ( Cariati, A; Piromalli, E, 2012)
"Gallbladder stones (cholecystolithiasis) are the main risk factor for gallbladder cancer (GBC), a lethal biliary malignancy with poor survival rates worldwide."1.56Evaluation of the chemopreventive potentials of ezetimibe and aspirin in a novel mouse model of gallbladder preneoplasia. ( Arrese, M; Bizama, C; Espinoza, JA; Ferreccio, C; García, P; Gómez, N; González, X; Guevara, F; Kalergis, AM; Lobos-González, L; Miquel, JF; Muñoz-Durango, N; Roa, JC; Rosa, L; Saavedra, N; Villegas, J; Wichmann, IA, 2020)
"Gallstones were identified."1.34Can pigment gallstones be induced by biliary stricture and prevented by medicine in Guinea pigs? ( Ling, XF; Xu, Z; Zhang, WH; Zhou, XS, 2007)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Rosa, L1
Lobos-González, L1
Muñoz-Durango, N1
García, P1
Bizama, C1
Gómez, N1
González, X1
Wichmann, IA1
Saavedra, N1
Guevara, F1
Villegas, J1
Arrese, M1
Ferreccio, C1
Kalergis, AM1
Miquel, JF1
Espinoza, JA1
Roa, JC1
Cho, E1
Park, CH1
Jun, CH1
Kim, HS1
Choi, SK1
Rew, JS1
Nie, R1
Luo, N1
Wang, J1
Cariati, A1
Piromalli, E1
Liu, E1
Sakoda, LC1
Gao, YT1
Rashid, A1
Shen, MC1
Wang, BS1
Deng, J1
Han, TQ1
Zhang, BH1
Fraumeni, JF1
Hsing, AW1
Xu, Z1
Ling, XF1
Zhang, WH1
Zhou, XS1

Reviews

1 review available for aspirin and Gallstones

ArticleYear
Limits and perspective of oral therapy with statins and aspirin for the prevention of symptomatic cholesterol gallstone disease.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:9

    Topics: Administration, Oral; Animals; Aspirin; Atherosclerosis; Cardiovascular Agents; Cholecystolithiasis;

2012

Other Studies

5 other studies available for aspirin and Gallstones

ArticleYear
Evaluation of the chemopreventive potentials of ezetimibe and aspirin in a novel mouse model of gallbladder preneoplasia.
    Molecular oncology, 2020, Volume: 14, Issue:11

    Topics: Animals; Aspirin; Chemoprevention; Cholecystolithiasis; Cholesterol; Cholesterol, Dietary; Chronic D

2020
Self-expandable metal stents for the extraction of common bile duct stones in patients receiving dual antiplatelet agents: a pilot study.
    Surgical endoscopy, 2018, Volume: 32, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cholangiopancreatography, Endoscopic Retrograde; Clopidogrel; Comm

2018
Very late drug-eluting stent thrombosis in the perioperative period of endoscopic choledocholithotomy.
    Acta cardiologica, 2009, Volume: 64, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis;

2009
Aspirin use and risk of biliary tract cancer: a population-based study in Shanghai, China.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biliary Tract Neoplasms; Case-Control

2005
Can pigment gallstones be induced by biliary stricture and prevented by medicine in Guinea pigs?
    World journal of gastroenterology, 2007, May-21, Volume: 13, Issue:19

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bilirubin; Calcium; Chenodeoxycholic Acid

2007