Page last updated: 2024-10-23

aspirin and Frostbite

aspirin has been researched along with Frostbite in 9 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Frostbite: Damage to tissues as the result of low environmental temperatures.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of pentoxifylline--a haemorrheologic agent along with aspirin--an analgesic agent was evaluated in the amelioration of the tissue damage due to experimentally induced frostbite in 5 groups (20 each) of rats with body weights ranging between 175 and 200 g."7.70Efficacy of pentoxifylline with aspirin in the treatment of frostbite in rats. ( Chauhan, SK; Purkayastha, SS; Roy, A; Selvamurthy, W; Verma, SS, 1998)
"Frostbite was produced experimentally in all the animals by exposing one of the hind limbs at -12 +/- 1 degree C with wind flow 25-30 lit/min for 30 min in a freezing-machine, with simultaneous recordings of rectal and ambient temperatures."5.31Immediate treatment of frostbite using rapid rewarming in tea decoction followed by combined therapy of pentoxifylline, aspirin & vitamin C. ( Banerjee, PK; Bhaumik, G; Chauhan, SK; Purkayastha, SS; Selvamurthy, W, 2002)
"The efficacy of pentoxifylline--a haemorrheologic agent along with aspirin--an analgesic agent was evaluated in the amelioration of the tissue damage due to experimentally induced frostbite in 5 groups (20 each) of rats with body weights ranging between 175 and 200 g."3.70Efficacy of pentoxifylline with aspirin in the treatment of frostbite in rats. ( Chauhan, SK; Purkayastha, SS; Roy, A; Selvamurthy, W; Verma, SS, 1998)
"Frostbite is a thermal injury caused when tissue is exposed to sub-zero temperatures (in degrees Celsius) long enough for ice crystals to form in the affected tissue."2.66Interventions for frostbite injuries. ( Davis, C; Lorentzen, AK; Penninga, L, 2020)
"Frostbite is most likely to happen in combination with accidents, intoxications or psychiatric emergencies and typically affects smaller, more exposed areas of the body, such as fingers, toes, nose, ears, cheeks and chin."2.52[Management of frostbite in and outside of the doctor's surgery]. ( Durrer, B, 2015)
"Treatment with aspirin 250 mg daily and intravenous iloprost 0."1.62Frostbite and Cold Agglutinin Disease: Coexistence of Two Entities Leading to Poor Clinical Outcomes. ( Andres, E; Cattelan, J; Guerrero-Niño, J; Jannot, X; Ledoux, MP; Lorenzo-Villalba, N; Nasco, E, 2021)
"Frostbite was produced experimentally in all the animals by exposing one of the hind limbs at -12 +/- 1 degree C with wind flow 25-30 lit/min for 30 min in a freezing-machine, with simultaneous recordings of rectal and ambient temperatures."1.31Immediate treatment of frostbite using rapid rewarming in tea decoction followed by combined therapy of pentoxifylline, aspirin & vitamin C. ( Banerjee, PK; Bhaumik, G; Chauhan, SK; Purkayastha, SS; Selvamurthy, W, 2002)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Tam, A1
Lyons, T1
Vennam, S1
Barnes, R1
Imray, C1
Jud, P1
Hafner, F1
Brodmann, M1
Lorentzen, AK1
Davis, C1
Penninga, L1
Lorenzo-Villalba, N1
Andres, E1
Guerrero-Niño, J1
Nasco, E1
Cattelan, J1
Jannot, X1
Ledoux, MP1
Durrer, B1
Cauchy, E1
Cheguillaume, B1
Chetaille, E1
Purkayastha, SS2
Bhaumik, G1
Chauhan, SK2
Banerjee, PK1
Selvamurthy, W2
Bilgiç, S1
Ozkan, H1
Ozenç, S1
Safaz, I1
Yildiz, C1
Roy, A1
Verma, SS1

Reviews

2 reviews available for aspirin and Frostbite

ArticleYear
Interventions for frostbite injuries.
    The Cochrane database of systematic reviews, 2020, 12-20, Volume: 12

    Topics: Amputation, Surgical; Aspirin; Bias; Drug Therapy, Combination; Epoprostenol; Fibrinolytic Agents; F

2020
[Management of frostbite in and outside of the doctor's surgery].
    Therapeutische Umschau. Revue therapeutique, 2015, Volume: 72, Issue:1

    Topics: Aspirin; Finger Injuries; Frostbite; General Practice; Humans; Rewarming; Toes

2015

Trials

1 trial available for aspirin and Frostbite

ArticleYear
A controlled trial of a prostacyclin and rt-PA in the treatment of severe frostbite.
    The New England journal of medicine, 2011, Jan-13, Volume: 364, Issue:2

    Topics: Adult; Aspirin; Combined Modality Therapy; Drug Therapy, Combination; Female; Fibrinolytic Agents; F

2011

Other Studies

6 other studies available for aspirin and Frostbite

ArticleYear
Early Use of Iloprost in Nonfreezing Cold Injury.
    Wilderness & environmental medicine, 2022, Volume: 33, Issue:3

    Topics: Aspirin; Cold Injury; Cold Temperature; Frostbite; Humans; Iloprost; Male; Microcirculation

2022
Frostbite of the hands after paragliding: a chilling experience.
    Lancet (London, England), 2019, 12-21, Volume: 394, Issue:10216

    Topics: Aspirin; Athletic Injuries; Betamethasone; Drug Therapy, Combination; Enoxaparin; Frostbite; Hand In

2019
Frostbite and Cold Agglutinin Disease: Coexistence of Two Entities Leading to Poor Clinical Outcomes.
    Medicina (Kaunas, Lithuania), 2021, Jun-08, Volume: 57, Issue:6

    Topics: Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Aspirin; Female; Frostbite; Humans; Rituximab; Wal

2021
Immediate treatment of frostbite using rapid rewarming in tea decoction followed by combined therapy of pentoxifylline, aspirin & vitamin C.
    The Indian journal of medical research, 2002, Volume: 116

    Topics: Animals; Ascorbic Acid; Aspirin; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Female; Free

2002
Treating frostbite.
    Canadian family physician Medecin de famille canadien, 2008, Volume: 54, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Anticoagulants; Aspirin; Ben

2008
Efficacy of pentoxifylline with aspirin in the treatment of frostbite in rats.
    The Indian journal of medical research, 1998, Volume: 107

    Topics: Animals; Aspirin; Cold Temperature; Drug Therapy, Combination; Female; Frostbite; Male; Necrosis; Pe

1998