Page last updated: 2024-10-23

aspirin and Foramen Ovale, Patent

aspirin has been researched along with Foramen Ovale, Patent in 42 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Foramen Ovale, Patent: A condition in which the FORAMEN OVALE in the ATRIAL SEPTUM fails to close shortly after birth. This results in abnormal communications between the two upper chambers of the heart. An isolated patent ovale foramen without other structural heart defects is usually of no hemodynamic significance.

Research Excerpts

ExcerptRelevanceReference
"In this prospective cohort study, we randomly assigned patients with PFO who had a cryptogenic stroke, in a 1:1 ratio, to dabigatran or aspirin group."9.51Dabigatran versus aspirin for stroke prevention after cryptogenic stroke with patent foramen ovale: A prospective study. ( Cai, D; Chen, S; He, J; Huang, P; Lai, Y; Sun, H; Wu, Q; Zhou, L, 2022)
"NAVIGATE ESUS was a double-blinded, randomised, phase 3 trial done at 459 centres in 31 countries that assessed the efficacy and safety of rivaroxaban versus aspirin for secondary stroke prevention in patients with ESUS."9.27Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial. ( Ameriso, SF; Bangdiwala, S; Berkowitz, SD; Connolly, SJ; Endres, M; Hart, RG; Kasner, SE; Lavados, P; Lindgren, A; Lutsep, H; Messé, SR; Muir, K; Mundl, H; Nedeltechev, K; Olavarria, V; Perera, K; Santo, G; Sharma, M; Shoamanesh, A; Spence, JD; Swaminathan, B; Veltkamp, R, 2018)
"We presented a patient suffered from stroke related to thalidomide therapy."8.84[Brief report: stroke in multiple myeloma patient treated with thalidomide]. ( Hashimoto, Y; Hirano, T; Ito, Y; Mori, A; Uchino, M; Yonemura, K, 2007)
"Main outcomes were stroke recurrence and major bleeding."6.66Aspirin or anticoagulation after cryptogenic stroke with patent foramen ovale: systematic review and meta-analysis of randomized controlled trials. ( Calabresi, P; Cupini, LM; Eusebi, P; Giannandrea, D; Ricci, S; Romoli, M, 2020)
"In this prospective cohort study, we randomly assigned patients with PFO who had a cryptogenic stroke, in a 1:1 ratio, to dabigatran or aspirin group."5.51Dabigatran versus aspirin for stroke prevention after cryptogenic stroke with patent foramen ovale: A prospective study. ( Cai, D; Chen, S; He, J; Huang, P; Lai, Y; Sun, H; Wu, Q; Zhou, L, 2022)
"NAVIGATE ESUS was a double-blinded, randomised, phase 3 trial done at 459 centres in 31 countries that assessed the efficacy and safety of rivaroxaban versus aspirin for secondary stroke prevention in patients with ESUS."5.27Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial. ( Ameriso, SF; Bangdiwala, S; Berkowitz, SD; Connolly, SJ; Endres, M; Hart, RG; Kasner, SE; Lavados, P; Lindgren, A; Lutsep, H; Messé, SR; Muir, K; Mundl, H; Nedeltechev, K; Olavarria, V; Perera, K; Santo, G; Sharma, M; Shoamanesh, A; Spence, JD; Swaminathan, B; Veltkamp, R, 2018)
" I have selected 4 translations in the field of vascular neurology in which I have been involved in different respects: (1) the translation of results from men to women, taking the example of aspirin which, in primary prevention, decreases the risk of myocardial infarction in men and the risk of cerebral infarction in women, the reason for this sex difference being so far unknown; (2) the 'inverse translational research', from bedside to bench, taking the example of the disease we have identified--CADASIL--and showing how the study of one patient and his family led to the identification of a gene, Notch3, so far unknown in humans and to the discovery of its key role in the physiology of vascular smooth muscle cells; (3) the translation from individual case reports to multidisciplinary trials taking the example of hemicraniectomy in malignant cerebral infarction and emphasizing the interest in such rare and severe conditions of pooling and reporting the results of randomized clinical trials before the results of individual trials, and (4) the translation from research to practice, emphasizing not the well-known 'evidence to practice gap' but the slippery slope of 'lack of evidence to overpractice', taking the example of patent foramen ovale closure in migraine."4.84Some translations in vascular neurology. The Johann Jacob Wepfer Award 2008. ( Bousser, MG, 2008)
"We presented a patient suffered from stroke related to thalidomide therapy."4.84[Brief report: stroke in multiple myeloma patient treated with thalidomide]. ( Hashimoto, Y; Hirano, T; Ito, Y; Mori, A; Uchino, M; Yonemura, K, 2007)
"When warfarin was the mainstay of anticoagulation for the prevention of cardioembolic stroke, the paradigm was essentially "we mustn't anticoagulate anyone unless we prove that the stroke was cardioembolic."3.91Anticoagulation in patients with Embolic Stroke of Unknown Source. ( Spence, JD, 2019)
"A cause other than paradoxical embolism was usually apparent in patients with recurrent neurologic events."2.77Closure or medical therapy for cryptogenic stroke with patent foramen ovale. ( Adams, H; Albers, GW; Felberg, R; Furlan, AJ; Herrmann, H; Kar, S; Landzberg, M; Massaro, J; Mauri, L; Raizner, A; Reisman, M; Wechsler, L, 2012)
"Aspirin was administered at 100 mg/d for six months after occlusion."2.75Transcatheter closure of patent foramen ovale with the Spider patent foramen ovale occluder: a prospective, single-center trial. ( Huang, T; Huang, WH; Huang, XS; Huang, YG; Shen, JJ; Xun, ZR; Zhang, CJ, 2010)
"Main outcomes were stroke recurrence and major bleeding."2.66Aspirin or anticoagulation after cryptogenic stroke with patent foramen ovale: systematic review and meta-analysis of randomized controlled trials. ( Calabresi, P; Cupini, LM; Eusebi, P; Giannandrea, D; Ricci, S; Romoli, M, 2020)
"Cryptogenic stroke is one-fourth among cerebral infarction, but most of them could be ascribed to embolic stroke."2.53[ESUS (embolic stroke of undetermined sources)]. ( Kitagawa, K, 2016)
"Aspirin was given as well as percutaneous endovascular PFO closure was performed with no immediate complication."2.47Patent foramen ovale and recurrent transient neurological symptoms: a case report and review of literature. ( Anamnart, C; Poungvarin, N, 2011)
"Stroke is a second cause of mortality worldwide and a leading cause of acquired disability in adults."1.38[Ulcerated plaques of the aorta as a cause of ischaemic stroke]. ( Hoffman, P; Kowalski, M; Michałowska, I; Rybicka, J, 2012)
"Cryptogenic stroke is part of the disease of stress-induced cerebrovascular disease."1.33A new theory of cryptogenic stroke and its relationship to patent foramen ovale; or, the puzzle of the missing extra risk. ( Eggers, AE, 2006)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (28.57)29.6817
2010's24 (57.14)24.3611
2020's6 (14.29)2.80

Authors

AuthorsStudies
Chen, S1
Cai, D1
Lai, Y1
He, J1
Wu, Q1
Huang, P1
Zhou, L1
Sun, H1
Sagris, D1
Georgiopoulos, G1
Perlepe, K1
Pateras, K1
Korompoki, E1
Makaritsis, K1
Vemmos, K1
Milionis, H1
Ntaios, G1
Han, Y1
Zhang, X1
Zhang, F1
Kasner, SE3
Randall, B1
Andersen, G1
Iversen, HK1
Roine, RO1
Sjostrand, C1
Rhodes, JF1
Søndergaard, L1
Romoli, M1
Giannandrea, D1
Eusebi, P1
Cupini, LM1
Ricci, S2
Calabresi, P1
Messé, SR2
Gronseth, GS1
Kent, DM1
Kizer, JR1
Homma, S1
Rosterman, L1
Carroll, JD1
Ishida, K1
Sangha, N1
Diener, HC1
Chutinet, A1
Easton, JD1
Granger, CB1
Kleine, E1
Marquardt, L1
Meyerhoff, J1
Zini, A1
Sacco, RL1
Swaminathan, B1
Lavados, P1
Sharma, M1
Muir, K1
Veltkamp, R1
Ameriso, SF1
Endres, M1
Lutsep, H1
Spence, JD2
Nedeltechev, K1
Perera, K1
Santo, G1
Olavarria, V1
Lindgren, A1
Bangdiwala, S1
Shoamanesh, A1
Berkowitz, SD1
Mundl, H1
Connolly, SJ1
Hart, RG1
Meier, B2
Melis, M1
Toni, D1
Tomizawa, Y1
Tanaka, R1
Sekiguchi, K1
Oji, Y1
Tanaka, Y1
Yamashiro, K1
Hattori, N1
Furlan, AJ2
Anglim, B1
Maher, N1
Cunningham, O1
Mulcahy, D1
Harbison, J1
O'Connell, M1
Polzin, A1
Dannenberg, L1
Sophia Popp, V1
Kelm, M1
Zeus, T1
Kitagawa, K1
Savino, K1
Maiello, M1
Pelliccia, F1
Ambrosio, G1
Palmiero, P1
Stern, S1
Cohen, MJ1
Gilon, D1
Leshno, M1
Brezis, M1
Hudsmith, L1
Thorne, S1
Clift, P1
Krizanic, F1
Sievert, H1
Pfeiffer, D1
Konorza, T1
Ferrari, M1
Figulla, HR1
Bousser, MG1
Sarens, T1
Herroelen, L1
Van Deyk, K1
Budts, W1
Scacciatella, P1
Butera, G1
Amato, G1
Tomassini, F1
Giorgi, M1
Marra, S1
Zhang, CJ1
Huang, YG1
Huang, XS1
Huang, T1
Huang, WH1
Shen, JJ1
Xun, ZR1
Fischer, D2
Haentjes, J1
Klein, G1
Schieffer, B2
Drexler, H2
Meyer, GP2
Schaefer, A2
Bhindi, R1
Ormerod, OJ1
Anamnart, C1
Poungvarin, N1
Mono, ML2
Geister, L1
Galimanis, A1
Jung, S1
Praz, F1
Arnold, M1
Fischer, U1
Wolff, S1
Findling, O1
Windecker, S1
Wahl, A1
Mattle, HP1
Nedeltchev, K2
Kalinczuk, L1
Lubiszewska, B1
Demkow, M1
Arauz, A1
Murillo, L1
Márquez, JM1
Tamayo, A1
Cantú, C1
Roldan, FJ1
Vargas-Barrón, J1
Barinagarrementeria, F1
Ramponi, F1
Wilson, MK1
Vedelago, J1
Bayfield, MS1
Reisman, M1
Massaro, J1
Mauri, L1
Adams, H1
Albers, GW1
Felberg, R1
Herrmann, H1
Kar, S1
Landzberg, M1
Raizner, A1
Wechsler, L1
Rybicka, J1
Kowalski, M1
Michałowska, I1
Hoffman, P1
Giger, JN1
Brannon, CB1
Eggers, AE1
Müller, M1
Paulsen, J1
Hoerauf, H1
Ito, Y2
Mori, A2
Yonemura, K2
Hashimoto, Y2
Hirano, T2
Uchino, M2
Vij, M1
Mowbray, D1
Ponnuthurai, FA1
van Gaal, WJ1
Burchell, A1
Mitchell, A1
Wilson, N1
Ormerod, O1
Fuchs, M1
Jategaonkar, S1
Hornig, B1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Double-blind, Evaluation in Secondary Stroke Prevention Comparing the EfficaCy and Safety of the Oral Thrombin Inhibitor Dabigatran Etexilate (110 mg or 150 mg, Oral b.i.d.) Versus Acetylsalicylic Acid (100 mg Oral q.d.) in Patients With Embol[NCT02239120]Phase 35,390 participants (Actual)Interventional2014-11-27Completed
A Prospective, Multicenter, Randomized Controlled Trial to Evaluate the Safety and Efficacy of the STARFlex® Septal Closure System Versus Best Medical Therapy in Patients With a Stroke and/or Transient Ischemic Attack Due to Presumed Paradoxical Embolism [NCT00201461]Phase 2/Phase 3900 participants (Anticipated)Interventional2003-06-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Adjudicated Composite of Non-fatal Stroke, Non-fatal Myocardial Infarction, or Cardiovascular Death

Adjudicated composite of non-fatal stroke, non-fatal myocardial infarction (MI), or cardiovascular death is a key secondary endpoint. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)4.80
Acetylsalicylic Acid, Aspirin (ASA) 100 mg5.40

Adjudicated Fatal Bleed

Adjudicated fatal bleeding was defined as a bleeding event which the Independent Event Adjudication Committee (IAC) determined as the primary cause of death or contributed directly to death. The annualised event rate represents the average number of events per patient during a 1-year period. Because there were 0 events in one treatment group, the hazard ratio is unable to be calculated. (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)0.00
Acetylsalicylic Acid, Aspirin (ASA) 100 mg0.05

Adjudicated Intracranial Hemorrhage

"Adjudicated intracranial haemorrhage comprised the subtypes of intracerebral bleeds, intraventricular bleeds, subdural bleeds, epidural bleeds, and subarachnoid bleeds. Microbleeds did not qualify as intracranial haemorrhage, except when they were symptomatic.~The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)0.67
Acetylsalicylic Acid, Aspirin (ASA) 100 mg0.63

Adjudicated Ischaemic Stroke

Adjudicated ischaemic stroke is a key secondary endpoint. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)3.97
Acetylsalicylic Acid, Aspirin (ASA) 100 mg4.71

Adjudicated Life-threatening Bleed

"Major bleeds were to be classified as life-threatening if they met one or more of the following criteria: fatal bleed, symptomatic intracranial bleed, reduction in haemoglobin of at least 5 grams/ deciliter (g/dL), transfusion of at least 4 units of packed red blood cells (equivalent to 9 units in Japan), associated with hypotension requiring the use of intravenous inotropic agents, or necessitated surgical intervention.~The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)0.76
Acetylsalicylic Acid, Aspirin (ASA) 100 mg0.91

Adjudicated Recurrent Stroke

Adjudicated recurrent stroke (ischemic, hemorrhagic, or unspecified) is presented. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, approximately 43 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)4.09
Acetylsalicylic Acid, Aspirin (ASA) 100 mg4.80

All-cause Death

All-cause death is presented. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)1.24
Acetylsalicylic Acid, Aspirin (ASA) 100 mg1.28

Any Bleed (Investigator-reported)

"This was the sum of all major and minor bleeds (Minor bleeds were clinical bleeds that did not fulfil the criteria for major bleeds), regardless of severity.~The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)15.21
Acetylsalicylic Acid, Aspirin (ASA) 100 mg11.64

Disabling Stroke

Disabling stroke (modified Rankin Scale greater than or equal to 4, as determined 3 months after recurrent stroke) is presented. The annualised event rate represents the average number of events per patient during a 1-year period. (NCT02239120)
Timeframe: From randomisation until full follow up period, up to 43 months

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)0.55
Acetylsalicylic Acid, Aspirin (ASA) 100 mg0.93

First Major Bleed (Adjudicated)

"First major bleed is primary safety endpoint. Major bleeds were defined according to the International Society of Thrombosis and Haemostasis (ISTH) definition as follows:~Symptomatic bleeding in a critical area or organ, such as intracranial, intraspinal, intraocular, retroperitoneal, intra-articular or pericardial, or intramuscular with compartment syndrome and/or,~Bleeding (which should be overt) associated with a reduction in haemoglobin of at least 2 grams/ decilitre (g/dL) (1.24 millimoles Per Litre (mmol/L)), or leading to transfusion of ≥2 units of blood or packed cells (equivalent to ≥4.5 units in Japan); the haemoglobin drop should be considered to be due to and temporally related to the bleeding event and/or,~Fatal bleed. The annualised event rate represents the average number of events per patient during a 1-year period." (NCT02239120)
Timeframe: Between the first trial medication intake up to 6 days after the last trial medication intake, approximately 42 months.

InterventionAnnualised event rate (%/ year) (Number)
Dabigatran Etexilate 110 or 150 Milligram (mg)1.84
Acetylsalicylic Acid, Aspirin (ASA) 100 mg1.33

Reviews

10 reviews available for aspirin and Foramen Ovale, Patent

ArticleYear
Antithrombotic Treatment in Cryptogenic Stroke Patients With Patent Foramen Ovale: Systematic Review and Meta-Analysis.
    Stroke, 2019, Volume: 50, Issue:11

    Topics: Anticoagulants; Aspirin; Fibrinolytic Agents; Foramen Ovale, Patent; Humans; Ischemic Attack, Transi

2019
Aspirin or anticoagulation after cryptogenic stroke with patent foramen ovale: systematic review and meta-analysis of randomized controlled trials.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020, Volume: 41, Issue:10

    Topics: Anticoagulants; Aspirin; Foramen Ovale, Patent; Humans; Ischemic Stroke; Middle Aged; Randomized Con

2020
Brief history of patent foramen ovale and stroke.
    Stroke, 2015, Volume: 46, Issue:2

    Topics: Aspirin; Endovascular Procedures; Foramen Ovale, Patent; Humans; Randomized Controlled Trials as Top

2015
[ESUS (embolic stroke of undetermined sources)].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:4

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Blood Coagulation Disorders; Clinical Trials as Topic;

2016
Patent foramen ovale and cryptogenic stroke: from studies to clinical practice: Position paper of the Italian Chapter, International Society Cardiovascular Ultrasound.
    International journal of clinical practice, 2016, Volume: 70, Issue:8

    Topics: Anticoagulants; Aspirin; Cardiac Catheterization; Echocardiography; Embolism, Paradoxical; Foramen O

2016
Some translations in vascular neurology. The Johann Jacob Wepfer Award 2008.
    Cerebrovascular diseases (Basel, Switzerland), 2008, Volume: 26, Issue:3

    Topics: Aspirin; Awards and Prizes; Biomedical Research; CADASIL; Cardiovascular Agents; Cardiovascular Dise

2008
Economy class syndrome complicated by stroke: a rare condition due to paradoxical embolism--a case report and review of the literature.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2011, Volume: 12, Issue:8

    Topics: Aircraft; Anticoagulants; Aspirin; Clopidogrel; Echocardiography; Embolism, Paradoxical; Foramen Ova

2011
Patent foramen ovale and recurrent transient neurological symptoms: a case report and review of literature.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2011, Volume: 94 Suppl 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Surgical Procedures; Echocardiography, Tra

2011
[Patent foramen ovale and stroke].
    Fortschritte der Neurologie-Psychiatrie, 2012, Volume: 80, Issue:5

    Topics: Anticoagulants; Aspirin; Fibrinolytic Agents; Foramen Ovale, Patent; Humans; Platelet Aggregation In

2012
[Brief report: stroke in multiple myeloma patient treated with thalidomide].
    Rinsho shinkeigaku = Clinical neurology, 2007, Volume: 47, Issue:9

    Topics: Aged; Anticoagulants; Aspirin; Embolism, Paradoxical; Foramen Ovale, Patent; Humans; Male; Multiple

2007

Trials

9 trials available for aspirin and Foramen Ovale, Patent

ArticleYear
Dabigatran versus aspirin for stroke prevention after cryptogenic stroke with patent foramen ovale: A prospective study.
    Clinical neurology and neurosurgery, 2022, Volume: 215

    Topics: Aspirin; Dabigatran; Foramen Ovale, Patent; Humans; Ischemic Stroke; Prospective Studies; Recurrence

2022
Comparison of Antiplatelet Therapies for Prevention of Patent Foramen Ovale-Associated Stroke.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female; Foramen Ov

2020
Practice advisory update summary: Patent foramen ovale and secondary stroke prevention: Report of the Guideline Subcommittee of the American Academy of Neurology.
    Neurology, 2020, 05-19, Volume: 94, Issue:20

    Topics: Adult; Aspirin; Atrial Fibrillation; Foramen Ovale, Patent; Humans; Platelet Aggregation Inhibitors;

2020
Dabigatran or Aspirin After Embolic Stroke of Undetermined Source in Patients With Patent Foramen Ovale: Results From RE-SPECT ESUS.
    Stroke, 2021, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Anticoagulants; Aspirin; Dabigatran; Double-Blind Method; Embolic Stroke; Embolis

2021
Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial.
    The Lancet. Neurology, 2018, Volume: 17, Issue:12

    Topics: Aged; Aspirin; Cohort Studies; Double-Blind Method; Factor Xa Inhibitors; Female; Foramen Ovale, Pat

2018
Clinical evaluation of a novel occluder device (Occlutech) for percutaneous transcatheter closure of patent foramen ovale (PFO).
    Clinical research in cardiology : official journal of the German Cardiac Society, 2008, Volume: 97, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alloys; Aspirin; Balloon Occlusion; Cardiac Catheterizat

2008
Patent foramen ovale closure and migraine: are we following the wrong pathway?
    Journal of neurology, 2009, Volume: 256, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Catheterization; Cardiac Surgical P

2009
Transcatheter closure of patent foramen ovale with the Spider patent foramen ovale occluder: a prospective, single-center trial.
    Chinese medical journal, 2010, Apr-05, Volume: 123, Issue:7

    Topics: Adolescent; Adult; Aged; Aspirin; Cardiac Catheterization; Echocardiography; Female; Foramen Ovale,

2010
Closure or medical therapy for cryptogenic stroke with patent foramen ovale.
    The New England journal of medicine, 2012, Mar-15, Volume: 366, Issue:11

    Topics: Adolescent; Adult; Anticoagulants; Aspirin; Clopidogrel; Combined Modality Therapy; Drug Therapy, Co

2012

Other Studies

23 other studies available for aspirin and Foramen Ovale, Patent

ArticleYear
Patent foramen ovale closure by using transesophageal echocardiography for cryptogenic stroke: single center experience in 132 consecutive patients.
    Journal of cardiothoracic surgery, 2020, Jan-09, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Aspirin; Cardiac Catheterization; Cardiac Surgical Procedures; Child; Contr

2020
Optimal stroke prevention in patients with patent foramen ovale.
    The Lancet. Neurology, 2018, Volume: 17, Issue:12

    Topics: Aspirin; Foramen Ovale, Patent; Humans; Rivaroxaban; Secondary Prevention; Stroke

2018
Anticoagulation in patients with Embolic Stroke of Unknown Source.
    International journal of stroke : official journal of the International Stroke Society, 2019, Volume: 14, Issue:4

    Topics: Anticoagulants; Aspirin; Embolism, Paradoxical; Foramen Ovale, Patent; Humans; Monitoring, Physiolog

2019
Optimal stroke prevention in patients with PFO.
    The Lancet. Neurology, 2019, Volume: 18, Issue:3

    Topics: Aspirin; Foramen Ovale, Patent; Humans; Recurrence; Rivaroxaban; Stroke

2019
Cerebral infarction in a case of Parry-Romberg syndrome.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2014, Volume: 23, Issue:2

    Topics: Adult; Aspirin; Atorvastatin; Cerebral Infarction; Diffusion Magnetic Resonance Imaging; Facial Hemi

2014
A rare case of cryptogenic stroke with an incidental finding of patent foramen ovale.
    Irish medical journal, 2015, Volume: 108, Issue:3

    Topics: Adult; Aspirin; Brain Infarction; Female; Foramen Ovale, Patent; Humans; Incidental Findings; Magnet

2015
Antiplatelet effects of clopidogrel and aspirin after interventional patent foramen ovale/ atrium septum defect closure.
    Platelets, 2016, Volume: 27, Issue:4

    Topics: Adult; Aged; Aspirin; Blood Platelets; Cardiac Surgical Procedures; Clopidogrel; Comorbidity; Female

2016
Cryptogenic stroke in a patient with a PFO: a decision analysis.
    The American journal of the medical sciences, 2008, Volume: 335, Issue:6

    Topics: Anticoagulants; Aspirin; Cardiac Catheterization; Decision Trees; Foramen Ovale, Patent; Humans; Int

2008
Spontaneous left atrial thrombus during patent foramen ovale closure.
    European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, 2008, Volume: 9, Issue:6

    Topics: Anticoagulants; Aspirin; Atrial Septum; Balloon Occlusion; Drug Therapy, Combination; Echocardiograp

2008
Transcatheter closure of patent foramen ovale (PFO) in patients with paradoxical embolism: procedural and follow-up results after implantation of the Amplatzer®-occluder device.
    Journal of interventional cardiology, 2011, Volume: 24, Issue:1

    Topics: Aspirin; Cardiac Catheterization; Clopidogrel; Echocardiography, Transesophageal; Embolism, Paradoxi

2011
Letter by Bhindi and Ormerod regarding article, "Lack of association between migraine headache and patent foramen ovale: results of a case-control study".
    Circulation, 2010, Dec-14, Volume: 122, Issue:24

    Topics: Aspirin; Case-Control Studies; Foramen Ovale, Patent; Humans; Migraine Disorders

2010
Patent foramen ovale may be causal for the first stroke but unrelated to subsequent ischemic events.
    Stroke, 2011, Volume: 42, Issue:10

    Topics: Adult; Aged; Aspirin; Brain Ischemia; Clopidogrel; Female; Follow-Up Studies; Foramen Ovale, Patent;

2011
Normal chest radiograph and ground glass opacities on a thoracic computed tomographic scan in a patient with diffuse alveolar haemorrhage due to dual antiplatelet therapy prescribed after patent foramen ovale percutaneous device closure.
    European heart journal, 2011, Volume: 32, Issue:23

    Topics: Adult; Aspirin; Clopidogrel; Drug Therapy, Combination; Female; Foramen Ovale, Patent; Hemoptysis; H

2011
Long-term risk of recurrent stroke in young cryptogenic stroke patients with and without patent foramen ovale.
    International journal of stroke : official journal of the International Stroke Society, 2012, Volume: 7, Issue:8

    Topics: Adolescent; Adult; Aspirin; Female; Fibrinolytic Agents; Foramen Ovale, Patent; Humans; Male; Middle

2012
Catastrophic pulmonary and paradoxical embolism.
    ANZ journal of surgery, 2011, Volume: 81, Issue:11

    Topics: Angiography; Aspirin; Cardiac Surgical Procedures; Critical Illness; Echocardiography, Transesophage

2011
[Ulcerated plaques of the aorta as a cause of ischaemic stroke].
    Kardiologia polska, 2012, Volume: 70, Issue:5

    Topics: Acenocoumarol; Aspirin; Echocardiography; Foramen Ovale, Patent; Humans; Hydroxymethylglutaryl-CoA R

2012
African-Americans and strokes: minutes and hours make the difference.
    Journal of National Black Nurses' Association : JNBNA, 2011, Volume: 22, Issue:2

    Topics: Aspirin; Black or African American; Female; Fibrinolytic Agents; Foramen Ovale, Patent; Health Statu

2011
A new theory of cryptogenic stroke and its relationship to patent foramen ovale; or, the puzzle of the missing extra risk.
    Medical hypotheses, 2006, Volume: 67, Issue:5

    Topics: Adult; Aged; Aspirin; Databases, Factual; Foramen Ovale, Patent; Humans; Middle Aged; Recurrence; Ri

2006
[Subtle, temporary, homonymous visual field defect--fatal causes?].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2007, Volume: 104, Issue:9

    Topics: Adult; Anticoagulants; Aspirin; Cerebral Infarction; Fibrinolytic Agents; Foramen Ovale, Patent; Hem

2007
[Late-onset hemorrhagic infarction in patients with patent foramen ovale: reports of two cases].
    Rinsho shinkeigaku = Clinical neurology, 2007, Volume: 47, Issue:9

    Topics: Acute-Phase Reaction; Aged; Aspirin; Cerebral Hemorrhage; Cerebral Infarction; Foramen Ovale, Patent

2007
Pregnancy outcome in patients with patent foramen ovale and cerebral embolism.
    European journal of obstetrics, gynecology, and reproductive biology, 2008, Volume: 140, Issue:1

    Topics: Adult; Anticoagulants; Aspirin; Embolism, Paradoxical; Female; Foramen Ovale, Patent; Heparin, Low-M

2008
Single centre experience with GORE-HELEX septal occluder for closure of PFO.
    Heart, lung & circulation, 2009, Volume: 18, Issue:2

    Topics: Adult; Aspirin; Cardiac Catheterization; Echocardiography; Female; Fibrinolytic Agents; Follow-Up St

2009
Transcatheter closure of patent foramen ovale in patients with paradoxical embolism. Procedural and follow-up results after implantation of the Starflex occluder device with conjunctive intensified anticoagulation regimen.
    Journal of interventional cardiology, 2008, Volume: 21, Issue:2

    Topics: Adult; Anticoagulants; Aspirin; Cardiac Catheterization; Embolism, Paradoxical; Female; Foramen Oval

2008