Page last updated: 2024-10-23

aspirin and Folic Acid Deficiency

aspirin has been researched along with Folic Acid Deficiency in 6 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inoue, F1
Walsh, RJ1
Dallman, PR1
Ma, J1
Stampfer, MJ1
Giovannucci, E1
Artigas, C1
Hunter, DJ1
Fuchs, C1
Willett, WC1
Selhub, J1
Hennekens, CH1
Rozen, R1
Basu, TK1
Nelson, MM1
Forfar, JO1
Alter, HJ1
Zvaifler, NJ1
Rath, CE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Folates in the Care of the Male Infertility[NCT01407432]Phase 3162 participants (Actual)Interventional2011-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for aspirin and Folic Acid Deficiency

ArticleYear
Nutritional anemias: relationship to genetic and pharmacological factors.
    Progress in clinical and biological research, 1981, Volume: 67

    Topics: Adolescent; Adult; Age Factors; Anemia; Anemia, Hypochromic; Aspirin; Black People; Child; Child, Pr

1981
Drug-vitamin interaction.
    International journal for vitamin and nutrition research. Supplement = Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Supplement, 1985, Volume: 27

    Topics: Anticonvulsants; Ascorbic Acid; Ascorbic Acid Deficiency; Aspirin; Drug Interactions; Drug-Related S

1985

Trials

1 trial available for aspirin and Folic Acid Deficiency

ArticleYear
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.
    Cancer research, 1997, Mar-15, Volume: 57, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; beta Carotene; Case-Control Studies; Coca

1997

Other Studies

3 other studies available for aspirin and Folic Acid Deficiency

ArticleYear
Folate supplements and phenytoin-salicylate interaction.
    Neurology, 1983, Volume: 33, Issue:1

    Topics: Adult; Aspirin; Drug Interactions; Folic Acid; Folic Acid Deficiency; Humans; Male; Phenytoin; Seizu

1983
Associations between drugs administered during pregnancy and congenital abnormalities of the fetus.
    British medical journal, 1971, Mar-06, Volume: 1, Issue:5748

    Topics: Abnormalities, Drug-Induced; Adult; Analgesics; Antacids; Antiemetics; Appetite Depressants; Ascorbi

1971
Interrelationship of rheumatoid arthritis, folic acid, and aspirin.
    Blood, 1971, Volume: 38, Issue:4

    Topics: Absorption; Arthritis, Rheumatoid; Aspirin; Dialysis; Erythrocytes; FIGLU Test; Folic Acid; Folic Ac

1971