Page last updated: 2024-10-23

aspirin and Fatty Liver with Encephalopathy

aspirin has been researched along with Fatty Liver with Encephalopathy in 247 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"The risk of Reye syndrome decreases with age, becoming extremely rare by the late teenage years."5.35FPIN's Clinical Inquiries. Aspirin use in children for fever or viral syndromes. ( Beutler, AI; Chesnut, GT; Jamieson, B; Mattingly, JC, 2009)
"During the study Reye's syndrome was not seen."5.29[Use of aspirin for fever by Russian immigrant children]. ( Ben-Noun, L, 1996)
"Aspirin has been the cornerstone of antiplatelet therapy in patients with acute coronary syndromes and is well accepted and recommended by several major healthcare organizations."3.96Aspirin rechallenge in an adult patient previously diagnosed with Reye syndrome. ( Magrum, BG; Pickworth, KK, 2020)
" In 1980 s, the relevance of aspirin for Reye's syndrome became a problem, then acetaminophen came into use for various kinds of cases such as children, pregnant women and the elderly for pain management or alleviation of fever."3.83[Side Effects of Acetaminophen and their Management]. ( Saeki, S, 2016)
" Fever always occurred before their admission and aspirin (n = 12) or acetaminophen (n = 7) was prescribed."3.71[Severe Reye syndrome: report of 14 cases managed in a pediatric intensive care unit over 11 years]. ( Brivet, M; Chevret, L; Debray, D; Devictor, D; Durand, P; Fabre, M; Thabet, F, 2002)
" The examples presented are ampicillin rash in infectious mononucleosis, Reye's syndrome and drug-induced agranulocytosis."3.67The combined effect of viruses and drugs in drug-induced diseases. ( Levy, M, 1984)
"Data collected from the Public Health Service Main Study of Reye's Syndrome and Medications were analyzed to assess the relationship between the development of Reye's syndrome and the dose of aspirin received during the antecedent respiratory or chickenpox illness."3.67Reye's syndrome and aspirin. Evidence for a dose-response effect. ( Gunn, WJ; Hurwitz, ES; Pinsky, PF; Schonberger, LB, 1988)
"The Reye syndrome is a complex disease that remains little-known despite its severity."2.47[The Reye syndrome]. ( Duh, D; Tanret, I, 2011)
"Reye syndrome is an extremely rare but severe and often fatal disease."2.44Aspirin and Reye syndrome: a review of the evidence. ( Schrör, K, 2007)
"Reye's syndrome is a serious, acute encephalopathy that has been linked with aspirin (acetylsalicylic acid) use in children and teenagers <18 years of age."2.43Reye's syndrome: the case for a causal link with aspirin. ( Glasgow, JF, 2006)
"As to the decline of Reye syndrome, recent literature data reveal that this is related to more accurate modern diagnosis of infectious, metabolic or toxic disease, reducing the percentage of idiopathic or true cases of Reye syndrome."2.41Reye syndrome revisited: a descriptive term covering a group of heterogeneous disorders. ( Casteels-Van Daele, M; Eggermont, E; Van Geet, C; Wouters, C, 2000)
"Classic Reye syndrome is now so rare in the USA that when an apparent case is encountered in a child who has not taken aspirin, other diagnoses should be considered."2.41[Reye's syndrome: the death of a syndrome? (Or death by a syndrome?)]. ( Calvani, M, 2000)
"Aspirin has been identified as one factor contributing to the metabolic disorder that occurs."2.40Reye's syndrome: an update. ( Ward, MR, 1997)
" The observation of a dose-response relation between risk of Reye's syndrome and dose of aspirin ingested during the antecedent illness provides further supportive evidence for a causal link between Reye's syndrome and aspirin."2.38Reye's syndrome. ( Hurwitz, ES, 1989)
"Fever and pain are the most common issues in pediatric patient management."2.36Use of antipyretic analgesics in the pediatric patient. ( Gladtke, E, 1983)
"We provided optimal treatment of severe hyperammonemia (>500 µmol/L) and cerebral edema, including high doses of arginine chloride, sodium benzoate, hemodialysis, mild hypothermia, and supportive care."1.62Reye Syndrome with Severe Hyperammonemia and a Good Neurological Outcome. ( Battelino, T; Bratina, N; Groselj, U; Herga, P; Klemenčič, S; Osredkar, D; Pribožič, L; Rajtar Osredkar, S; Repič Lampret, B; Vidmar, I; Žerjav Tanšek, M, 2021)
"Reye syndrome is a rare but a very dangerous emergency that children and teenagers suffer."1.46REYE (RAY'S) SYNDROME: A PROBLEM EVERYONE SHOULD REMEMBER. ( Boyarchuk, O; Chornomydz, A; Chornomydz, I, 2017)
"Reye's syndrome is an acute illness characterized by hepatic encephalopathy and fatty degeneration of the liver."1.38[21-year-old woman with Reye's syndrome after influenza]. ( Böhm, M; Kaplan, BT; Link, A, 2012)
"Twelve cases of Reye's syndrome are presented with different degrees of encephalopathy, hyperammonemia and hypoglycemia; associated to acetyl salicylic acid (ASA) ingestion."1.35Reyes's syndrome, encephalopathy, hyperammonemia and acetyl salicylic acid ingestion in a city hospital of Buenos Aires, Argentina. ( Coll, C; Fernández, MA; Filinger, EJ; Lemberg, A; Perazzo, JC; Romay, S; Rosello, DO, 2009)
"The risk of Reye syndrome decreases with age, becoming extremely rare by the late teenage years."1.35FPIN's Clinical Inquiries. Aspirin use in children for fever or viral syndromes. ( Beutler, AI; Chesnut, GT; Jamieson, B; Mattingly, JC, 2009)
"This report describes a patient with Reye's syndrome and serves as a reminder for health professionals to continue to discourage the use of aspirin for the treatment of viral infections."1.32Reye's syndrome: down but not out. ( Bhutta, AT; Schexnayder, SM; Van Savell, H, 2003)
"An association between Reye's syndrome and the ingestion of aspirin (acetylsalicylic acid) was claimed, although no proof of causation was ever established."1.31Is aspirin a cause of Reye's syndrome? A case against. ( Fiallos, MR; Hanhan, UA; Orlowski, JP, 2002)
"Reye's syndrome was diagnosed on the basis of her clinical course, and the presence of hepatic microvesicular steatosis and characteristic electron microscopic changes in the hepatocyte mitochondria."1.30Co-existence of hepatitis A and adult Reye's syndrome. ( Bain, VG; Duerksen, DR; Jewell, LD; Mason, AL, 1997)
"The decline in Reye's syndrome after the aspirin warnings cannot be explained entirely, as has been proposed, by improved diagnosis of 'Reye-like' inherited metabolic and other disorders: this would not account for the greater decline of the high scoring subgroup which also contained those cases most likely to resemble 'classical' Reye's syndrome and to have received aspirin."1.29The changing clinical pattern of Reye's syndrome 1982-1990. ( Bruce, JC; Glasgow, JF; Hall, SM; Hardie, RM; Mowat, AP; Newton, LH; Stephenson, JB, 1996)
"During the study Reye's syndrome was not seen."1.29[Use of aspirin for fever by Russian immigrant children]. ( Ben-Noun, L, 1996)
"Cases of Reye's syndrome declined both in numbers (from a peak of 79 in 1983/4 to 19 in 1988/9) and in median age."1.28Trends in the incidence of Reye's syndrome and the use of aspirin. ( Banks, JH; Glasgow, JF; Hall, SM; Porter, JD; Robinson, PH, 1990)
"There have been over 3,500 cases of Reye's syndrome reported to the CDC since 1973."1.28Reye's syndrome in an adult. ( Eagel, BA; Krugman, D; Vinoski, B, 1989)
"Like human patients with Reye's syndrome, these rats showed hyperammonemia, compromised fatty acid oxidation, and accumulation of branched chain amino acid oxidation metabolites."1.28Hepatic metabolic alterations in rats treated with low-dose endotoxin and aspirin: an animal model of Reye's syndrome. ( Corkey, BE; Douglas, SD; Kilpatrick, LE; Polin, RA, 1989)
" We challenge these premises and discuss a number of technical errors that underlie Feinstein's writings: he generally ignores the tendency of nondifferential exposure misclassification to dilute associations; he inappropriately interchanges measure of disease occurrence, which leads him to erroneous assertions regarding differences among studies; and he asserts that absence of a dose-response gradient precludes causality, despite the fact that causal effects need not follow a monotonic dose-response curve over the entire range of exposure."1.28Scientific standards of criticism: a reaction to "Scientific standards in epidemiologic studies of the menace of daily life," by A.R. Feinstein. ( Greenland, S; Kelsey, JL; Savitz, DA; Stolley, PD, 1990)
"5 to 5 x 10(4)IU/mL, approximately 1/100 the therapeutic dosage for humans) and interleukin-1 (IL-1) (1."1.28Experimental study on Reye's syndrome: inhibitory effect of interferon alfa on acetylsalicylate-induced injury to rat liver mitochondria. ( Enzan, H; Kurashige, T; Miyahara, M; Takeda, K; Tomoda, T, 1992)
"A 4-year-old girl with juvenile rheumatoid arthritis developed fever, protracted vomiting, disturbance of consciousness and decorticate posture following the administration of salicylate."1.27Simulated Reye's syndrome and salicylate therapy. ( Horikoshi, T; Okada, S; Yamashita, F; Yoshida, I, 1984)
"In Europe Reye's syndrome is a rather rare but often fatal disease affecting children and teenagers."1.27[Reye syndrome--a status review of current concepts of its pathogenesis]. ( Plauth, M, 1984)
"Effects of influenza B infection, aspirin treatment and hyperammonemia on the level of free fatty acids, total lipids and triacylglycerols in serum and liver of an animal model of Reye's syndrome are reported here."1.27Free fatty acids in an animal model of Reye's syndrome. ( Deshmukh, DR; Deshmukh, GD; Radin, NS; Shope, TC, 1983)
"Aspirin remains the cornerstone of treatment for juvenile arthritis, although tolmetin may be more effective in controlling the fever of systemic-onset disease."1.27Treatment of juvenile arthritis. ( Baum, J, 1983)
"Patients with Reye's syndrome who have been given aspirin are said to maintain higher-than-anticipated salicylate concentrations in blood, for longer than expected."1.27Measurement of true salicylate concentrations in serum from patients with Reye's syndrome. ( Capaci, MT; Jabbour, JT; Kang, ES; Schwenzer, K; Todd, TA, 1983)
"Reye's syndrome has been infrequently described in children receiving long-term salicylate therapy."1.27Reye's syndrome associated with long-term aspirin therapy. ( Hendriksen, D; Torretti, D; Williams, RH; Woods, M; Young, RS, 1984)
"The parents of 106 children who had had Reye's syndrome and those of 185 comparison children who had febrile illnesses were interviewed in order to compare preadmission medication exposure rates in the two groups."1.27Preadmission antipyretics in Reye's syndrome. ( Glasgow, JF; Hall, SM; Hancock, P; Plaster, PA, 1988)
"The number of cases of Reye syndrome reported annually to the Centers for Disease Control declined markedly between 1980 and 1985."1.27National patterns of aspirin use and Reye syndrome reporting, United States, 1980 to 1985. ( Arrowsmith, JB; Faich, GA; Kennedy, DL; Kuritsky, JN, 1987)
" In Australia, the pediatric usage of aspirin has been extremely low for the past 25 years (less than 1% of total dosage units sold), with paracetamol (acetaminophen) dominating the pediatric analgesic and antipyretic market."1.27A catch in the Reye. ( Gillis, J; Kilham, HA; Orlowski, JP, 1987)
"The incidence of the Reye syndrome in Spain has been retrospectively reviewed from 1980 to 1984."1.27[Reye's syndrome in Spain, 1980-1984 (A cooperative study: Pediatric Intensive Care Section of the Asociación Española de Pediatría)]. ( Asencio, MJ; Belmonte, JA; Calvo, C; Delgado, A; Doménech, P; Escudero, G; Gómez Calzado, A; Labay, M; Martínez-Gutiérrez, A; Palomeque, A, 1986)
"Patients with Reye's syndrome (RS) whose degree of severity was classified as stage 0 (alert and awake) were compared with patients with a severity classification of stage 1 or greater."1.27Reye's syndrome. An epidemiologic analysis of mild disease. ( Campbell, RJ; Hall, LJ; Halpin, TJ; Holtzhauer, FJ, 1986)
"Adult Reye's syndrome (ARS) is an infrequently diagnosed condition that typically affects patients younger than age 35 years."1.27Reye's syndrome in adults. A case report and review of the literature. ( Geisinger, KR; Gilliam, J; Peters, LJ; Roach, ES; Van Noord, G; Wiener, GJ, 1986)
"The high percentage of patients with Reye's syndrome exposed to salicylates (greater than or equal to 90%) in this and prior studies suggests that, though the reported incidence of Reye's syndrome has declined in recent years, concomitant with a decline in salicylate use among children, a majority of Reye's syndrome cases may be attributable to salicylate use."1.27Public Health Service study of Reye's syndrome and medications. Report of the main study. ( Barrett, MJ; Bregman, D; Burlington, DB; Drage, JS; Gunn, WJ; Hurwitz, ES; Kaslow, RA; Pinsky, P; Quinnan, GV; Schonberger, LB, 1987)
"The incidence of Reye syndrome has been decreasing in Michigan, perhaps as a result of decreased aspirin use among children."1.27Decreasing trends in Reye syndrome and aspirin use in Michigan, 1979 to 1984. ( Hall, WN; McGee, H; Monto, AS; Remington, PL; Rowley, D, 1986)
"The average annual incidence of Reye syndrome reported through national surveillance was lower during 1981 to 1984 than during the previous five surveillance years."1.27Changing epidemiology of Reye syndrome in the United States. ( Barrett, MJ; Hurwitz, ES; Rogers, MF; Schonberger, LB, 1986)
"Seven children with juvenile rheumatoid arthritis had a syndrome characterized by hemorrhage and neurologic, hepatic, hematologic, and metabolic manifestations."1.27Acute hemorrhagic, hepatic, and neurologic manifestations in juvenile rheumatoid arthritis: possible relationship to drugs or infection. ( Griscelli, C; Hadchouel, M; Prieur, AM, 1985)
"Fever was measured with a thermometer in 114 ill children, 103 of whom had at least one measured temperature of 37."1.27Antipyretic use among children during the 1983 influenza season. ( Brandenburg, N; Glezen, WP; Gustafson, TL; Johnson, CC; Taylor, JP, 1985)
"The vomiting of Reye's syndrome is usually persistent, lasting for 24 to 96 hours before the onset of serious brain signs."1.27Management of Reye's syndrome: need for early diagnosis and intravenous treatment of stage I non-comatose cases. ( Partin, JC, 1985)
"A 14-year-old girl in whom Reye syndrome developed during aspirin therapy for an inflammatory disorder proven to be systemic lupus erythematosus is reported."1.27Reye syndrome associated with aspirin therapy for systemic lupus erythematosus. ( Bale, JF; Corbett, AJ; Flanders, DJ; Hansen, JR; McCray, PB, 1985)
"The incidence of RS among children with juvenile rheumatoid arthritis is significantly greater than the incidence of RS among children who do not have juvenile rheumatoid arthritis."1.27Reye syndrome and juvenile rheumatoid arthritis in Michigan. ( Hall, WN; McGee, H; Preston, G; Remington, PL; Sarniak, AP; Shabino, CL, 1985)
"Aspirin is a possible cofactor with influenza B virus in Reye's syndrome."1.27Influenza B virus model of Reye's syndrome in mice: the effect of aspirin. ( Davis, LE; Green, CL; Wallace, JM, 1985)
" In 87% of the cases receiving aspirin, their maximum daily dosage did not exceed recommended levels, but their doses were higher than those of controls receiving aspirin."1.26Reye's syndrome and medication use. ( Campbell, RJ; Correa-Villaseñor, A; Hall, LJ; Halpin, TJ; Holtzhauer, FJ; Hurwitz, ES; Lanese, R; Rice, J, 1982)
"Recent studies of Reye syndrome (RS) patients have suggested aspirin treatment as a possible factor in the etiology of this often fatal childhood disorder."1.26Interactions of aspirin and other potential etiologic factors in an animal model of Reye syndrome. ( Deshmukh, DR; Maassab, HF; Mason, M, 1982)
"The observations suggest that Reye's syndrome may result from an aspirin-induced aberration in the immune response to a viral infection."1.26Reye's syndrome and aspirin use: a possible immunological relationship. ( Bailey, JM; Low, CE; Pupillo, MB, 1982)
"In the epidemiologic setting of influenza B outbreaks, children who have the acute onset of noninflammatory encephalopathy associated with elevated serum transaminase levels, hypoprothrombinemia, and elevated blood ammonia levels should be considered to have Reye's syndrome."1.26Diagnostic criteria for influenza B-associated Reye's syndrome: clinical vs. pathologic criteria. ( Bregman, D; Corey, L; Gregg, MB; Rubin, RJ, 1977)
"A case of hepatotoxicity and encephalopathy (Reye's syndrome?) associated with salicylate therapy is presented and the aetiology of this syndrome is discussed."1.25Acute liver failure and encephalopathy (Reye's syndrome?) during salicylate therapy. ( Koivikko, A; Mäkelä, AL; Sillanpää, M, 1975)

Research

Studies (247)

TimeframeStudies, this research(%)All Research%
pre-1990145 (58.70)18.7374
1990's48 (19.43)18.2507
2000's39 (15.79)29.6817
2010's10 (4.05)24.3611
2020's5 (2.02)2.80

Authors

AuthorsStudies
Pribožič, L1
Žerjav Tanšek, M1
Herga, P1
Osredkar, D1
Rajtar Osredkar, S1
Vidmar, I1
Repič Lampret, B1
Klemenčič, S1
Bratina, N1
Battelino, T1
Groselj, U1
Yang, T1
Wijaya, WA1
Cao, C1
Magrum, BG1
Pickworth, KK1
Mount, M1
Toltzis, P1
Conde-Cardona, G1
Contreras-Puentes, N1
Polo-Martínez, M1
Dinakaran, D1
Sergi, CM1
Chornomydz, I1
Boyarchuk, O1
Chornomydz, A1
Saeki, S1
Selves, A1
Ruiz, S1
Crognier, L1
Conil, JM1
Bonneville, F1
Georges, B1
Dupuy, M1
Fourcade, O1
Geeraerts, T1
Ahrens-Nicklas, RC1
Edmondson, AC1
Ficicioglu, C1
Pugliese, A1
Beltramo, T1
Torre, D1
Lemberg, A1
Fernández, MA1
Coll, C1
Rosello, DO1
Romay, S1
Perazzo, JC1
Filinger, EJ1
Beutler, AI1
Chesnut, GT1
Mattingly, JC1
Jamieson, B1
Johnson, CC2
Ownby, DR1
Tanret, I1
Duh, D1
Bassareo, PP1
Fanos, V1
Iacovidou, N1
Mercuro, G1
Bennett, CL1
Starko, KM1
Thomsen, HS1
Cowper, S1
Sartor, O1
Macdougall, IC1
Qureshi, ZP1
Bookstaver, PB1
Miller, AD1
Norris, LB1
Xirasagar, S1
Trenery, A1
Lopez, I1
Kahn, A1
Murday, A1
Luminari, S1
Cournoyer, D1
Locatelli, F1
Ray, P1
Mattison, DR1
Link, A1
Kaplan, BT1
Böhm, M1
Aronoff, DM1
Macdonald, S1
Bhutta, AT1
Van Savell, H1
Schexnayder, SM1
Deepak, S1
Raj, RS1
Sibi, NS1
Joseph, W1
Thomas, M1
Andres, E1
Chow, EL1
Cherry, JD1
Harrison, R1
McDiarmid, SV1
Bhuta, S1
Waller, P1
Suvarna, R1
Abe, T1
Sakae, M1
Hanaka, S1
Matsumoto, A1
Xia, JX1
Wang, YX1
van Bever, HP1
Quek, SC1
Lim, T1
Pecar, A1
Glasgow, JF9
Fitzgerald, DA1
Schrör, K1
Andresen, BD2
Alexander, MS2
Ng, KJ2
Bianchine, JR2
Hall, SM10
Daugherty, CC1
McAdams, AJ1
Partin, JS1
Tomáśová, H1
Nevoral, J1
Pachl, J1
Kincl, V1
Marmo, E1
Gladtke, E1
Yoshida, I4
Yamashita, F3
Addy, DP1
Berlin, CM1
Okada, S1
Horikoshi, T1
Levy, M1
Cornali, R1
Mazzoni, PL1
Pozzi, A1
D'Amico, E1
Martens, ME1
Lee, CP1
Rarey, KE3
Rush, NL1
Davis, JA2
Deshmukh, DR4
Plauth, M1
Budd, RA1
Rothwell, R1
Kang, ES2
Olson, G1
Jabbour, JT2
Solomon, SS1
Heimberg, M1
Sabesin, S1
Griffith, JF1
Deshmukh, GD1
Shope, TC1
Radin, NS1
Liston, AJ1
Drost, RA1
Young, RS1
Torretti, D1
Williams, RH1
Hendriksen, D1
Woods, M1
Murphy, DH1
Orlowski, JP4
Söderman, P1
Horwitz, RI2
Feinstein, AR2
Harvey, MR1
Brown, RD2
Wilson, JT2
Offerhaus, L1
Burke, BL1
Baum, J1
Brown, AK1
Fikrig, S1
Finberg, L1
Todd, TA1
Capaci, MT1
Schwenzer, K1
Halpin, TJ4
Holtzhauer, FJ3
Campbell, RJ3
Hall, LJ3
Correa-Villaseñor, A2
Lanese, R2
Rice, J2
Hurwitz, ES9
Simmons, VP1
Bailey, JM1
Low, CE1
Pupillo, MB1
Maassab, HF1
Mason, M1
Velásquez Jones, L1
Check, W1
Waldman, RJ1
Hall, WN3
McGee, H3
Van Amburg, G1
Glezen, WP2
Hoekelman, RA1
Mortimer, EA2
Hall, W1
Tonsgard, JH2
Huttenlocher, PR1
Visentin, M1
Bellasio, R1
Tacconi, MT1
Newton, L1
Casteels-Van Daele, M8
Eggermont, E4
Baird, RE1
Foley, C1
Bresee, J1
Schonberger, LB5
Shindell, S1
Khan, AS1
Kent, J1
Maciejewski, CS1
Moore, R2
Yoshino, M1
Watanabe, J1
Lockey, D1
Matthews, AJ1
Smith, TC1
Hardie, RM1
Newton, LH1
Bruce, JC1
Mowat, AP1
Stephenson, JB1
Quillen, TM1
Trost, LC1
Lemasters, JJ1
Ben-Noun, L1
Kutukculer, N1
Yagci, RV1
Duerksen, DR1
Jewell, LD1
Mason, AL1
Bain, VG1
Valencia, AM1
Quevedo, FW1
Quintos, LS1
Ward, MR1
Kauffman, RE2
Bray, PF1
Nunn, J1
Lowry, L1
Lowry, R1
Singh, S1
Monto, AS2
Middleton, B2
Gray, A1
Hill, J1
Hasegawa, O1
Johnson, GM1
Tanasescu, S1
Lévesque, H1
Thuillez, C1
Prior, MJ1
Nelson, EB1
Temple, AR1
Doire, TL1
Van Geet, C3
Wouters, C3
Mizuguchi, M1
Calvani, M1
Willcox, ML1
McGovern, MC2
Stewart, MC2
Caksen, H1
Güler, E1
Alper, M1
Ustünbaş, HB1
Autret-Leca, E2
Jonville-Béra, AP2
Llau, ME2
Bavoux, F2
Saudubray, JM2
Laugier, J2
Devictor, D3
Barbier, P2
Dyer, C2
Hanhan, UA1
Fiallos, MR1
Yamanouchi, H1
Imataka, G1
Langford, NJ1
Thabet, F1
Durand, P1
Chevret, L1
Fabre, M1
Debray, D1
Brivet, M1
Linnemann, CC1
Ueda, K1
Hug, G1
Schaeffer, A1
Clark, A1
Schiff, GM1
Thaler, MM1
Corey, L1
Rubin, RJ1
Bregman, D2
Gregg, MB1
Douglas, RG1
Sillanpää, M1
Mäkelä, AL1
Koivikko, A1
Rosenfeld, RG1
Liebhaber, MI1
Soumerai, SB1
Ross-Degnan, D1
Kahn, JS1
Gutknecht, J1
Davis, DL1
Buffler, P1
Hancock, L1
Henry, DA1
Sanson-Fisher, RW1
Tomoda, T1
Takeda, K1
Kurashige, T1
Enzan, H1
Miyahara, M1
Kundu, RK1
Getz, GS1
Jolliet, P1
Widmann, JJ1
Savitz, DA1
Greenland, S1
Stolley, PD1
Kelsey, JL1
Takayanagi, M1
Kakinuma, H1
Yamamoto, S1
Nakajima, H1
Williams, FM1
Ferner, RE1
Graham, M1
Blain, PG1
Alberti, KG1
Rawlins, MD1
Porter, JD1
Robinson, PH1
Banks, JH1
Dolphin, CT1
Caldwell, J1
Smith, RL1
Lorz, U1
Glötzner, FL1
Fairhurst, H1
Holmes, A1
Davidson, LE1
Kilpatrick-Smith, L1
Hale, DE1
Douglas, SD2
Forsyth, BW1
Acampora, D1
Shapiro, ED1
Viscoli, CM1
Henner, R1
Holabird, NB1
Jones, BA1
Karabelas, AD1
Eagel, BA1
Vinoski, B1
Krugman, D1
Holman, RT1
Danks, DM1
Andreoli, A1
Bonora, G1
Luciani, L1
Perletti, L1
Donaldson, M1
Fleming, P1
Kilpatrick, LE1
Polin, RA1
Corkey, BE1
Kolata, G3
Denny, FW1
Tarlow, M1
Roeser, HP1
Remington, PL4
Sullivan, K1
Marks, JS1
Siegel, J1
Dahl, G1
Nordin, P1
Ghada, A1
Olsson, T1
Maru, F1
Starck, L1
Sullivan, KM1
Guignard, JP1
Gouyon, JB1
Geubelle, F1
Bhandari, B1
Sareen, D1
Mandowara, SL1
Jacklitsch, M1
Leyland, S1
Ikeda, A1
Kuroda, Y1
Kakigi, R1
Oda, K1
Yamamoto, K1
Shibasaki, H1
Caveney, S1
Baral, J1
Pinsky, PF1
Gunn, WJ2
Plaster, PA1
Hancock, P1
Braham, J1
Ghosh, HK1
Hall, RW1
Naess, K1
Roberts, RJ1
Arrowsmith, JB1
Kennedy, DL1
Kuritsky, JN1
Faich, GA1
Rowe, PH1
Gillis, J1
Kilham, HA1
Román, GC1
Munden, PM1
Waagner, D1
Ledbetter, EO1
Palomeque, A1
Doménech, P1
Martínez-Gutiérrez, A1
Asencio, MJ1
Belmonte, JA1
Calvo, C1
Delgado, A1
Escudero, G1
Gómez Calzado, A1
Labay, M1
Pribble, C1
Osborn, L1
Visser, HK1
Morris, LA1
Klimberg, R1
Peters, LJ1
Wiener, GJ1
Gilliam, J1
Van Noord, G1
Geisinger, KR1
Roach, ES1
Yolles, BJ1
Connors, JC1
Grufferman, S1
Feely, J1
Baboolal, R1
Monaghan, H1
Ward, OC1
Mann, RD1
Lunde, PK1
Banco, L1
Barrett, MJ2
Pinsky, P1
Drage, JS1
Kaslow, RA1
Burlington, DB1
Quinnan, GV1
Aagenoes, O1
Gray, JD1
Blaschke, TF1
Peterson, RG1
Rowley, D1
Rahwan, GL1
Rahwan, RG1
Rogers, MF1
Takahashi, M1
Mason, W1
Hadchouel, M1
Prieur, AM1
Griscelli, C1
Taylor, JP1
Gustafson, TL1
Brandenburg, N1
Clark, JH1
Nagamori, K1
Fitzgerald, JF1
Velásquez-Jones, L1
Partin, JC1
Hansen, JR1
McCray, PB1
Bale, JF1
Corbett, AJ1
Flanders, DJ1
Simell, O1
Hollister, JR1
Shabino, CL1
Preston, G1
Sarniak, AP1
Davis, LE1
Green, CL1
Wallace, JM1
Hilty, MD1
Romshe, CA1
Delamater, PV1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of High Omega-3 Fish Intake on Lipid Peroxidation[NCT01183520]30 participants (Actual)Interventional2010-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

32 reviews available for aspirin and Fatty Liver with Encephalopathy

ArticleYear
Co-ingestion of aspirin and acetaminophen promoting fulminant liver failure: A critical review of Reye syndrome in the current perspective at the dawn of the 21st century.
    Clinical and experimental pharmacology & physiology, 2018, Volume: 45, Issue:2

    Topics: Acetaminophen; Aspirin; Child; Drug Interactions; Drug Therapy, Combination; Humans; Liver Failure,

2018
An 8-year-old girl with abdominal pain and mental status changes.
    Pediatric emergency care, 2015, Volume: 31, Issue:6

    Topics: Abdominal Pain; Acute Disease; Ankle Injuries; Arthralgia; Aspirin; Child; Consciousness Disorders;

2015
Reye's and Reye's-like syndromes.
    Cell biochemistry and function, 2008, Volume: 26, Issue:7

    Topics: Aspirin; Humans; Metabolic Diseases; Reye Syndrome

2008
[The Reye syndrome].
    Journal de pharmacie de Belgique, 2011, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Nervous System Diseases; Prognosis;

2011
Antiplatelet therapy in children: why so different from adults'?
    Current pharmaceutical design, 2012, Volume: 18, Issue:21

    Topics: Adult; Age Factors; Aspirin; Blood Platelets; Child Development; Child, Preschool; Dipyridamole; Hum

2012
Linking drugs to obscure illnesses: lessons from pure red cell aplasia, nephrogenic systemic fibrosis, and Reye's syndrome. a report from the Southern Network on Adverse Reactions (SONAR).
    Journal of general internal medicine, 2012, Volume: 27, Issue:12

    Topics: Aspirin; Drug-Related Side Effects and Adverse Reactions; Erythropoietin; Female; Gadolinium; Humans

2012
[Reye syndrome and drug induced encephalopathy].
    Rinsho shinkeigaku = Clinical neurology, 2003, Volume: 43, Issue:11

    Topics: Animals; Aspirin; Brain; Child; Child, Preschool; Cholesterol Esters; Humans; Iatrogenic Disease; In

2003
Reye's syndrome: the case for a causal link with aspirin.
    Drug safety, 2006, Volume: 29, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Reye Syndrome; United Kingdom; Unit

2006
Aspirin and Reye syndrome: a review of the evidence.
    Paediatric drugs, 2007, Volume: 9, Issue:3

    Topics: Aspirin; Child; Energy Metabolism; Humans; Liver; Reye Syndrome

2007
[Untoward side effects of acetylsalicylic acid].
    La Clinica terapeutica, 1984, Nov-15, Volume: 111, Issue:3

    Topics: Adolescent; Adult; Angioedema; Aspirin; Asthma; Child; Child, Preschool; Female; Fetus; Gastrointest

1984
Use of antipyretic analgesics in the pediatric patient.
    The American journal of medicine, 1983, Nov-14, Volume: 75, Issue:5A

    Topics: Acetaminophen; Adolescent; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemic

1983
[Etiological mechanism of Reye's syndrome--from the viewpoint of metabolic disorders].
    Nihon rinsho. Japanese journal of clinical medicine, 1984, Volume: 42, Issue:12

    Topics: Ammonia; Animals; Aspirin; Child; Child, Preschool; Fatty Acids; Female; Humans; Infant; Male; Mitoc

1984
Advances in pediatric pharmacology and toxicology.
    Advances in pediatrics, 1983, Volume: 30

    Topics: Animals; Anti-Bacterial Agents; Aspirin; Attention Deficit Disorder with Hyperactivity; Biological A

1983
Reye's syndrome: an update.
    The Nurse practitioner, 1997, Volume: 22, Issue:12

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Incidence; Nurse Practi

1997
[Neurological complications with analgesics].
    Ryoikibetsu shokogun shirizu, 1999, Issue:27 Pt 2

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebral Hemorrhage; Headache; Humans;

1999
[Pharmacology of aspirin].
    La Revue de medecine interne, 2000, Volume: 21 Suppl 1

    Topics: Adult; Aged; Angina Pectoris; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Br

2000
Reye syndrome revisited: a descriptive term covering a group of heterogeneous disorders.
    European journal of pediatrics, 2000, Volume: 159, Issue:9

    Topics: Aspirin; Child; Humans; Reye Syndrome

2000
[Reye's and Reye's-like syndromes].
    Ryoikibetsu shokogun shirizu, 2000, Issue:30 Pt 5

    Topics: Aspirin; Cytokines; Diagnosis, Differential; Humans; Infant; Influenza, Human; Mitochondria, Liver;

2000
[Reye's syndrome: the death of a syndrome? (Or death by a syndrome?)].
    Recenti progressi in medicina, 2000, Volume: 91, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Diagnosis, Differential; Humans; Reye Syndr

2000
Reye syndrome--insights on causation and prognosis.
    Archives of disease in childhood, 2001, Volume: 85, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Prognosis; Reye Syndrom

2001
[Reye's syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 7

    Topics: Age Factors; Aspirin; Biomarkers; Drug Utilization; Humans; Influenza, Human; Japan; Jaundice; Reye

2001
[Mitochondrial diseases due to drug toxicity].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 4

    Topics: Animals; Antibiotics, Antineoplastic; Aspirin; Humans; Mitochondria; Mitochondrial Diseases; Reye Sy

2002
Metabolic mechanisms in Reye syndrome. End of a Mystery?
    American journal of diseases of children (1960), 1976, Volume: 130, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Aspirin; Brain Diseases; Carbamoyl-Phosphate Synthase

1976
Effects of professional and media warnings about the association between aspirin use in children and Reye's syndrome.
    The Milbank quarterly, 1992, Volume: 70, Issue:1

    Topics: Aspirin; Centers for Disease Control and Prevention, U.S.; Child; Consumer Organizations; Drug Indus

1992
Reye's syndrome and aspirin: a review.
    British journal of clinical practice. Supplement, 1990, Volume: 70

    Topics: Aspirin; Bias; Case-Control Studies; Child; Humans; Incidence; Reye Syndrome; Risk Factors; United K

1990
Progress in Reye syndrome: epidemiology, biochemical mechanisms and animal models.
    Digestive diseases (Basel, Switzerland), 1989, Volume: 7, Issue:3

    Topics: Adolescent; Animals; Aspirin; Child; Child, Preschool; Disease Models, Animal; Endotoxins; Escherich

1989
Reye's syndrome.
    Epidemiologic reviews, 1989, Volume: 11

    Topics: Aspirin; Australia; Humans; Reye Syndrome; United Kingdom; United States

1989
Control of polyunsaturated acids in tissue lipids.
    Journal of the American College of Nutrition, 1986, Volume: 5, Issue:2

    Topics: Acrodermatitis; alpha-Linolenic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Child; Crohn Dis

1986
[Reye's syndrome and aspirin].
    Revue medicale de Liege, 1988, Jan-01, Volume: 43, Issue:1

    Topics: Acetaminophen; Aspirin; Chickenpox; Diagnosis, Differential; Humans; Influenza, Human; Reye Syndrome

1988
Aspirin poisoning.
    Indian pediatrics, 1986, Volume: 23 Suppl

    Topics: Aspirin; Child; Emergencies; Humans; Reye Syndrome; Risk Factors

1986
Reye's syndrome and aspirin: a review.
    Journal of the Royal Society of Medicine, 1986, Volume: 79, Issue:10

    Topics: Aspirin; Child; Humans; Reye Syndrome

1986
Antipyretics and analgesics in children.
    Developmental pharmacology and therapeutics, 1985, Volume: 8, Issue:1

    Topics: Acetaminophen; Acid-Base Equilibrium; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child

1985

Other Studies

215 other studies available for aspirin and Fatty Liver with Encephalopathy

ArticleYear
Reye Syndrome with Severe Hyperammonemia and a Good Neurological Outcome.
    The American journal of case reports, 2021, Oct-11, Volume: 22

    Topics: Aspirin; Brain Edema; Child, Preschool; Humans; Hyperammonemia; Liver Failure, Acute; Male; Reye Syn

2021
Spontaneous regression of a Reye's tumor: A case report.
    Asian journal of surgery, 2023, Volume: 46, Issue:8

    Topics: Aspirin; Fibroma; Humans; Reye Syndrome

2023
Aspirin rechallenge in an adult patient previously diagnosed with Reye syndrome.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2020, Jan-08, Volume: 77, Issue:2

    Topics: Acute Coronary Syndrome; Aspirin; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Reye S

2020
50 Years Ago in The Journal of Pediatrics: Aspirin and Reye Syndrome.
    The Journal of pediatrics, 2020, Volume: 222

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; History, 20th Century; Humans; Pediatrics;

2020
[Remembering Reye's Syndrome in times of COVID-19].
    Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2020, Volume: 37, Issue:5

    Topics: Adult; Aspirin; COVID-19; Humans; Reye Syndrome; SARS-CoV-2

2020
REYE (RAY'S) SYNDROME: A PROBLEM EVERYONE SHOULD REMEMBER.
    Georgian medical news, 2017, Issue:272

    Topics: Adolescent; Antipyretics; Aspirin; Child; Child, Preschool; Humans; Infant; Reye Syndrome

2017
[Side Effects of Acetaminophen and their Management].
    Masui. The Japanese journal of anesthesiology, 2016, Volume: 65, Issue:7

    Topics: Acetaminophen; Aspirin; Chronic Pain; Cyclooxygenase 1; Fever; Humans; Pain Management; Reye Syndrom

2016
[Aspirin and its danger: Reye syndrome in young adult].
    Annales francaises d'anesthesie et de reanimation, 2013, Volume: 32, Issue:11

    Topics: Acyclovir; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Aspirin; Brain Edema; Coma; De

2013
Reyes's syndrome, encephalopathy, hyperammonemia and acetyl salicylic acid ingestion in a city hospital of Buenos Aires, Argentina.
    Current drug safety, 2009, Volume: 4, Issue:1

    Topics: Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Argentina; Aspartate Aminotransferase

2009
FPIN's Clinical Inquiries. Aspirin use in children for fever or viral syndromes.
    American family physician, 2009, Dec-15, Volume: 80, Issue:12

    Topics: Adolescent; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool;

2009
Have the efforts to prevent aspirin-related Reye's syndrome fuelled an increase in asthma?
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2011, Volume: 41, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; H

2011
[21-year-old woman with Reye's syndrome after influenza].
    Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:38

    Topics: Ammonia; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Edema; Diagnosis, Differential; Ele

2012
Aspirin and Reye's syndrome: discovery of aspirin and paracetamol.
    Drug safety, 2002, Volume: 25, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; History,

2002
Adverse drug reaction update.
    Adverse drug reactions and toxicological reviews, 2002, Volume: 21, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bupropion; Chemical and Drug Induced Liver Injury;

2002
Aspirin use to be banned in under 16 year olds.
    BMJ (Clinical research ed.), 2002, Nov-02, Volume: 325, Issue:7371

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Humans; Infan

2002
Reye's syndrome: down but not out.
    Southern medical journal, 2003, Volume: 96, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child, Preschool; Diagnosis, Differential; Fatal O

2003
Reye's syndrome.
    The Journal of the Association of Physicians of India, 2003, Volume: 51

    Topics: Adolescent; Aspirin; Fatal Outcome; Humans; Liver; Male; Reye Syndrome

2003
Labeling for oral and rectal over-the-counter drug products containing aspirin and nonaspirin salicylates; Reye's Syndrome warning. Final rule.
    Federal register, 2003, Apr-17, Volume: 68, Issue:74

    Topics: Administration, Oral; Administration, Rectal; Adolescent; Antidiarrheals; Aspirin; Child; Contraindi

2003
Drug-induced hepatotoxicity.
    The New England journal of medicine, 2003, Nov-13, Volume: 349, Issue:20

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Liver Injury; Child; Dru

2003
Reassessing Reye syndrome.
    Archives of pediatrics & adolescent medicine, 2003, Volume: 157, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Female; Humans; Respiratory Tract Infection

2003
Is aspirin a cause of Reye's syndrome?
    Drug safety, 2004, Volume: 27, Issue:1

    Topics: Aspirin; Humans; Reye Syndrome; United Kingdom

2004
[Oral aspirin caused Reye's syndrome in a child].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2004, Volume: 42, Issue:4

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Edema; Child; Coma; Fe

2004
Aspirin, Reye syndrome, Kawasaki disease, and allergies; a reconsideration of the links.
    Archives of disease in childhood, 2004, Volume: 89, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Hypersensitivity; Humans; Mucocutaneous Lymph

2004
[Acetylsalicylic acid in the 4-year old child with middle ear inflammation].
    Medizinische Monatsschrift fur Pharmazeuten, 2006, Volume: 29, Issue:8

    Topics: Aspirin; Child, Preschool; Humans; Otitis Media; Reye Syndrome

2006
Aspirin and Reye syndrome.
    Paediatric drugs, 2007, Volume: 9, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Drug Labeling

2007
Aspirin and Reye's disease: a reinterpretation.
    Lancet (London, England), 1982, Apr-17, Volume: 1, Issue:8277

    Topics: Aspirin; Child; Drug Interactions; Humans; Methods; Reye Syndrome

1982
The aspirin/Reye's syndrome link.
    Lancet (London, England), 1982, Dec-11, Volume: 2, Issue:8311

    Topics: Aspirin; Humans; Reye Syndrome; Stevens-Johnson Syndrome; Sulfonamides

1982
Aspirin and Reye's syndrome.
    Lancet (London, England), 1983, Mar-12, Volume: 1, Issue:8324

    Topics: Aspirin; Child; Humans; Reye Syndrome

1983
Aspirin and Reye's syndrome.
    Lancet (London, England), 1983, Jul-09, Volume: 2, Issue:8341

    Topics: Acute Disease; Adolescent; Aspirin; Brain Edema; Child; Child, Preschool; Female; Humans; Infant; In

1983
Aspirin esterase activity and Reye's syndrome.
    Lancet (London, England), 1984, Jul-07, Volume: 2, Issue:8393

    Topics: Adult; Aspirin; Carboxylic Ester Hydrolases; Child; Humans; Reye Syndrome

1984
Cold comfort for hot children.
    British medical journal (Clinical research ed.), 1983, Apr-09, Volume: 286, Issue:6372

    Topics: Acetaminophen; Aspirin; Child; Child, Preschool; Fever; Humans; Infant; Reye Syndrome

1983
Reye's syndrome.
    British medical journal (Clinical research ed.), 1983, Jul-16, Volume: 287, Issue:6386

    Topics: Aspirin; Child; Child, Preschool; Humans; Infant; Reye Syndrome; United Kingdom; United States

1983
Simulated Reye's syndrome and salicylate therapy.
    Acta paediatrica Scandinavica, 1984, Volume: 73, Issue:4

    Topics: Arthritis, Juvenile; Aspirin; Child, Preschool; Diagnosis, Differential; Female; Humans; Liver; Micr

1984
The combined effect of viruses and drugs in drug-induced diseases.
    Medical hypotheses, 1984, Volume: 14, Issue:3

    Topics: Agranulocytosis; Ampicillin; Aspirin; Drug Hypersensitivity; Humans; Infectious Mononucleosis; Reye

1984
[Reye's syndrome in a 4-month old infant].
    Minerva pediatrica, 1984, May-15, Volume: 36, Issue:9

    Topics: Aspirin; Chickenpox; Humans; Infant; Influenza, Human; Male; Reye Syndrome

1984
Reye's syndrome: salicylates and mitochondrial functions.
    Biochemical pharmacology, 1984, Sep-15, Volume: 33, Issue:18

    Topics: Animals; Aspirin; Calcium; Humans; Hydroxybutyrates; Mitochondria; Mitochondria, Liver; NAD; Oxidati

1984
Altered auditory brainstem evoked responses in the ferret model for Reye's syndrome.
    International journal of pediatric otorhinolaryngology, 1984, Volume: 7, Issue:3

    Topics: Ammonia; Animals; Aspirin; Audiometry; Audiometry, Evoked Response; Brain Stem; Disease Models, Anim

1984
[Reye syndrome--a status review of current concepts of its pathogenesis].
    Zeitschrift fur Gastroenterologie, 1984, Volume: 22, Issue:7

    Topics: Aflatoxins; Ammonia; Aspirin; Carbamoyl-Phosphate Synthase (Ammonia); Child; Fatty Acids, Nonesterif

1984
Reye's syndrome and aspirin.
    Drug and therapeutics bulletin, 1984, Oct-08, Volume: 22, Issue:20

    Topics: Adolescent; Aspirin; Child; Child, Preschool; Fever; Humans; Infant; Reye Syndrome

1984
Spotting Reye's syndrome while there's still time.
    RN, 1983, Volume: 46, Issue:12

    Topics: Aspirin; Child, Preschool; Critical Care; Female; Humans; Nursing Assessment; Reye Syndrome

1983
Development of encephalopathic features similar to Reye syndrome in rabbits.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:19

    Topics: Acetaminophen; Animals; Aspirin; Disease Models, Animal; Encephalitis; Fatty Acids, Nonesterified; F

1984
Free fatty acids in an animal model of Reye's syndrome.
    Biochimica et biophysica acta, 1983, Sep-20, Volume: 753, Issue:2

    Topics: Ammonia; Animals; Aspirin; Carnivora; Diet; Disease Models, Animal; Fatty Acids, Nonesterified; Ferr

1983
ASA and Reye's syndrome: an update.
    Canadian Medical Association journal, 1983, Oct-01, Volume: 129, Issue:7

    Topics: Adolescent; Aspirin; Child; Humans; Reye Syndrome

1983
[Acetylsalicylic acid and Reye's syndrome].
    Nederlands tijdschrift voor geneeskunde, 1983, Aug-20, Volume: 127, Issue:34

    Topics: Aspirin; Child; Humans; Reye Syndrome

1983
Reye's syndrome associated with long-term aspirin therapy.
    JAMA, 1984, Feb-10, Volume: 251, Issue:6

    Topics: Adolescent; Aspirin; Child, Preschool; Female; Humans; Infant; Reye Syndrome

1984
PHS initiates new study on aspirin-Reye link--but is it really necessary?
    American pharmacy, 1984, Volume: NS24, Issue:3

    Topics: Aspirin; Humans; Reye Syndrome; United States; United States Public Health Service

1984
Aspirin and Reye's syndrome. How strong an association?
    Postgraduate medicine, 1984, Volume: 75, Issue:6

    Topics: Aspirin; Child; Child, Preschool; Diagnosis, Differential; Drug Labeling; Humans; Infant; Research D

1984
[Is there any connection between Reye's syndrome and acetylsalicylic acid?].
    Lakartidningen, 1984, May-16, Volume: 81, Issue:20

    Topics: Aspirin; Child; Child, Preschool; Humans; Infant; Reye Syndrome

1984
Case-control research. Temporal precedence and other problems of the exposure-disease relationship.
    Archives of internal medicine, 1984, Volume: 144, Issue:6

    Topics: Adult; Aspirin; Child; Epidemiologic Methods; Female; Humans; Research Design; Reye Syndrome; Risk;

1984
Aspirin may pose Reye's risk in children with flu, varicella.
    Hospital practice (Office ed.), 1982, Volume: 17, Issue:8

    Topics: Adolescent; Aspirin; Chickenpox; Child; Child, Preschool; Humans; Influenza, Human; Reye Syndrome

1982
Aspirin consumption and severity of Reye's syndrome.
    Pediatrics, 1983, Volume: 71, Issue:2

    Topics: Aspirin; Child; Humans; Reye Syndrome

1983
[Pediatric aspirin and Reye's syndrome: suspected but not yet condemned].
    Nederlands tijdschrift voor geneeskunde, 1983, Jan-08, Volume: 127, Issue:2

    Topics: Adolescent; Aspirin; Child; Child, Preschool; Humans; Reye Syndrome

1983
Aspirin and Reye syndrome--statement challenged.
    Pediatrics, 1983, Volume: 71, Issue:3

    Topics: Aspirin; Child; Humans; Infant; Reye Syndrome

1983
Treatment of juvenile arthritis.
    American family physician, 1983, Volume: 27, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Juvenile; Aspirin; Child;

1983
Aspirin and Reye syndrome.
    The Journal of pediatrics, 1983, Volume: 102, Issue:1

    Topics: Aspirin; Drug Labeling; Humans; Reye Syndrome

1983
Measurement of true salicylate concentrations in serum from patients with Reye's syndrome.
    Clinical chemistry, 1983, Volume: 29, Issue:6

    Topics: Aspirin; Blood Proteins; Child; Chlorides; Chromatography, Thin Layer; False Positive Reactions; Fer

1983
Aspirin and Reye's syndrome.
    JAMA, 1983, Jun-17, Volume: 249, Issue:23

    Topics: Acute Disease; Adolescent; Aspirin; Child; Female; Humans; Infant; Male; Reye Syndrome

1983
Salicylates and Reye's syndrome.
    JAMA, 1983, Sep-16, Volume: 250, Issue:11

    Topics: Aspirin; Humans; Reye Syndrome; Salicylates; Terminology as Topic

1983
Reye's syndrome and aspirin use: a possible immunological relationship.
    Prostaglandins, leukotrienes, and medicine, 1982, Volume: 8, Issue:3

    Topics: Animals; Aspirin; Humans; Immunity; Lymphocytes; Male; Mice; Reye Syndrome; Virus Diseases

1982
Interactions of aspirin and other potential etiologic factors in an animal model of Reye syndrome.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:23

    Topics: Ammonia; Animals; Arginine; Aspartate Aminotransferases; Aspirin; Diet; Disease Models, Animal; Ferr

1982
[Relation between the administration of salicylates in various viral infections and the appearance of Reye's syndrome].
    Boletin medico del Hospital Infantil de Mexico, 1982, Volume: 39, Issue:6

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Fever; Humans; Reye Syndrome; S

1982
Reye's syndrome-aspirin link: a bit stronger.
    JAMA, 1982, Mar-19, Volume: 247, Issue:11

    Topics: Acute Disease; Adolescent; Aspirin; Child; Fever; Humans; Reye Syndrome; Risk

1982
Aspirin as a risk factor in Reye's syndrome.
    JAMA, 1982, Jun-11, Volume: 247, Issue:22

    Topics: Acute Disease; Adolescent; Aspirin; Child; Disease Outbreaks; Fever; Humans; Michigan; Reye Syndrome

1982
Aspirin and Reye syndrome. Committee on Infectious Diseases.
    Pediatrics, 1982, Volume: 69, Issue:6

    Topics: Aspirin; Chickenpox; Child; Epidemiologic Methods; Humans; Influenza, Human; Reye Syndrome; United S

1982
Reye syndrome and aspirin use: the role of prodromal illness severity in the assessment of relative risk.
    Pediatrics, 1982, Volume: 69, Issue:6

    Topics: Aspirin; Child; Epidemiologic Methods; Humans; Research Design; Reye Syndrome; Risk; United States

1982
RS Working Group. Aspirin Foundation of America, Inc. Reye syndrome and salicylates: a spurious association.
    Pediatrics, 1982, Volume: 70, Issue:1

    Topics: Aspirin; Child; Epidemiologic Methods; Humans; Reye Syndrome

1982
Reye's syndrome and medication use.
    JAMA, 1982, Aug-13, Volume: 248, Issue:6

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aspirin; Child; Child, Preschool; Female; Humans; I

1982
Aspirin and Reye's syndrome.
    American journal of diseases of children (1960), 1982, Volume: 136, Issue:11

    Topics: Adolescent; Aspirin; Chickenpox; Child; Humans; Influenza, Human; Reye Syndrome; Virus Diseases

1982
Take two aspirin and call me in the morning. Salicylate use and Reye's syndrome.
    American journal of diseases of children (1960), 1982, Volume: 136, Issue:11

    Topics: Aspirin; Chickenpox; Child; Humans; Influenza, Human; Reye Syndrome; Virus Diseases

1982
Reye syndrome and salicylates.
    International journal of epidemiology, 1982, Volume: 11, Issue:4

    Topics: Aspirin; Chickenpox; Child; Humans; Influenza, Human; Reye Syndrome; Risk

1982
Aspirin products.
    The Medical letter on drugs and therapeutics, 1981, Jul-24, Volume: 23, Issue:15

    Topics: Aspirin; Buffers; Delayed-Action Preparations; Drug Combinations; Humans; Reye Syndrome; Solutions;

1981
Michigan studies of Reye's Syndrome, aspirin, suggest preventive measures available.
    Michigan medicine, 1981, Volume: 80, Issue:26

    Topics: Aspirin; Child; Humans; Michigan; Reye Syndrome

1981
Salicylates and Reye's syndrome.
    Pediatrics, 1981, Volume: 68, Issue:5

    Topics: Aspirin; Child; Humans; Infant; Reye Syndrome

1981
Reye syndrome model in rats: protection against liver abnormalities by L-carnitine and acetyl-L-carnitine.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:2

    Topics: Acetylcarnitine; Acyl Coenzyme A; Animals; Aspirin; Carnitine; Coenzyme A; Disease Models, Animal; K

1995
Reye's syndrome in the British Isles: report for 1990/91 and the first decade of surveillance.
    Communicable disease report. CDR review, 1993, Jan-01, Volume: 3, Issue:1

    Topics: Adolescent; Aspirin; Child; Child, Preschool; Female; Humans; Incidence; Infant; Male; Population Su

1993
Reye's syndrome.
    BMJ (Clinical research ed.), 1994, Nov-26, Volume: 309, Issue:6966

    Topics: Antiemetics; Aspirin; Child; Humans; Reye Syndrome

1994
Reye's syndrome: lessons for family physicians.
    American family physician, 1994, Nov-15, Volume: 50, Issue:7

    Topics: Aspirin; Diagnosis, Differential; Family Practice; Genetic Diseases, Inborn; Humans; Infant; Metabol

1994
Reye's syndrome.
    BMJ (Clinical research ed.), 1994, Aug-06, Volume: 309, Issue:6951

    Topics: Antiemetics; Aspirin; Case-Control Studies; Child; Humans; Reye Syndrome

1994
Reduction of deaths after drug labelling for risk of Reye's syndrome.
    Lancet (London, England), 1993, Jan-09, Volume: 341, Issue:8837

    Topics: Aspirin; Bias; Child; Child, Preschool; Drug Labeling; Humans; Reye Syndrome

1993
Reduction of deaths after drug labelling for risk of Reye's syndrome.
    Lancet (London, England), 1993, Jan-09, Volume: 341, Issue:8837

    Topics: Aspirin; Child; Child, Preschool; Drug Labeling; Humans; Reye Syndrome

1993
Aspirin and Reye's syndrome.
    Lancet (London, England), 1993, Apr-10, Volume: 341, Issue:8850

    Topics: Adolescent; Aspirin; Case-Control Studies; Centers for Disease Control and Prevention, U.S.; Child;

1993
Reye's syndrome.
    BMJ (Clinical research ed.), 1994, Apr-02, Volume: 308, Issue:6933

    Topics: Antiemetics; Aspirin; Child; Child, Preschool; Humans; Reye Syndrome; Risk Factors

1994
The dilemma over foreign-language labeling of over-the-counter drugs.
    The Journal of legal medicine, 1994, Volume: 15, Issue:1

    Topics: Advertising; Aspirin; Drug Labeling; Duty to Warn; Hispanic or Latino; Humans; Infant; Language; Mal

1994
Reye's syndrome 30 years on.
    BMJ (Clinical research ed.), 1993, Oct-16, Volume: 307, Issue:6910

    Topics: Adolescent; Aspirin; Child; Child, Preschool; Humans; Reye Syndrome

1993
Sudden onset of ornithine carbamoyltransferase deficiency after aspirin ingestion.
    Journal of inherited metabolic disease, 1993, Volume: 16, Issue:5

    Topics: Adult; Aspirin; Coma; Humans; Male; Ornithine Carbamoyltransferase Deficiency Disease; Reye Syndrome

1993
Aspirin and breast feeding.
    Anaesthesia and intensive care, 1993, Volume: 21, Issue:2

    Topics: Aspirin; Breast Feeding; Female; Humans; Infant; Reye Syndrome

1993
Reye's syndrome and the use of aspirin.
    Scottish medical journal, 1996, Volume: 41, Issue:1

    Topics: Aspirin; Child; Humans; Reye Syndrome

1996
The changing clinical pattern of Reye's syndrome 1982-1990.
    Archives of disease in childhood, 1996, Volume: 74, Issue:5

    Topics: Aspirin; Child; Child, Preschool; Health Education; Humans; Infant; Reye Syndrome; Severity of Illne

1996
Myth & facts ... about Reye's syndrome.
    Nursing, 1996, Volume: 26, Issue:5

    Topics: Adolescent; Aspirin; Child; Humans; Reye Syndrome; Virus Diseases

1996
The mitochondrial permeability transition: a new pathophysiological mechanism for Reye's syndrome and toxic liver injury.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Animals; Aspirin; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Cyclosporine; Male; Memb

1996
[Use of aspirin for fever by Russian immigrant children].
    Harefuah, 1996, Jun-16, Volume: 130, Issue:12

    Topics: Adolescent; Aspirin; Child; Child, Preschool; Fever; Hepatic Encephalopathy; Humans; Infant; Israel;

1996
Our experience in Reye's syndrome.
    Journal of pediatric gastroenterology and nutrition, 1996, Volume: 23, Issue:3

    Topics: Aspirin; Child; Child, Preschool; Female; Humans; Infant; Male; Reye Syndrome

1996
Co-existence of hepatitis A and adult Reye's syndrome.
    Gut, 1997, Volume: 41, Issue:1

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; DNA, Viral; Female; Hepatitis A; He

1997
Reye's syndrome: not of historical interest only.
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:10

    Topics: Aspirin; Chickenpox; Child, Preschool; Female; Humans; Reye Syndrome

1997
Reye's syndrome and salicylate use, by Karen M. Starko, MD, et al, Pediatrics, 1980;66:859-864; and National patterns of aspirin use and Reye syndrome reporting, United States, 1980 to 1985, by Janet B. Arrowsmith et al, Pediatrics, 1987;79:858-863.
    Pediatrics, 1998, Volume: 102, Issue:1 Pt 2

    Topics: Aspirin; Child; History, 20th Century; Humans; Reye Syndrome; Salicylates

1998
Are we still abusing aspirin?
    Archives of internal medicine, 1998, Nov-23, Volume: 158, Issue:21

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Multiple Organ Failure; Plate

1998
The use of aspirin in children under 12 years old attending a paediatric dentistry department in a dental hospital.
    Health trends, 1994, Volume: 26, Issue:1

    Topics: Aspirin; Child; Child, Preschool; Dental Service, Hospital; England; Humans; Pediatric Dentistry; Re

1994
Aspirin in acute rheumatic fever.
    Indian pediatrics, 1998, Volume: 35, Issue:11

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chickenpox; Child; Humans; Influenz

1998
The disappearance of Reye's syndrome--a public health triumph.
    The New England journal of medicine, 1999, May-06, Volume: 340, Issue:18

    Topics: Aspirin; Child; Diagnosis, Differential; Drug Labeling; Humans; Incidence; Reye Syndrome; Risk Facto

1999
The mechanism of inhibition of beta-oxidation by aspirin metabolites in skin fibroblasts from Reye's syndrome patients and controls.
    Biochimica et biophysica acta, 1999, May-31, Volume: 1454, Issue:1

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Antioxidants; Aspirin; Catalysis; Child; Fibroblasts; Humans; Mito

1999
Whatever happened to Reye's syndrome? Did it ever really exist?
    Critical care medicine, 1999, Volume: 27, Issue:8

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Australia; Biopsy; Child; Child, Presc

1999
Reye's syndrome.
    The New England journal of medicine, 1999, Sep-09, Volume: 341, Issue:11

    Topics: Adolescent; Aspirin; Child; Drug Labeling; Humans; Reye Syndrome

1999
Pediatric ibuprofen use increases while incidence of Reye's syndrome continues to decline.
    Clinical pediatrics, 2000, Volume: 39, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Ibuprofen; Reye Syndrome;

2000
Action stat. Reye's syndrome.
    Nursing, 1999, Volume: 29, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Emergency Nursing; Female; Humans; Influenz

1999
Salicylates, nitric oxide, malaria, and Reye's syndrome.
    Lancet (London, England), 2001, Jun-09, Volume: 357, Issue:9271

    Topics: Aspirin; Cause of Death; Child; Developing Countries; Female; Health Promotion; Humans; Madagascar;

2001
Lesson of the week: Reye's syndrome and aspirin: lest we forget.
    BMJ (Clinical research ed.), 2001, Jun-30, Volume: 322, Issue:7302

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Contraindications; Humans; Infant; Male; Re

2001
A fatal case of Reye syndrome after varicella and ingestion of aspirin.
    The Journal of dermatology, 2001, Volume: 28, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chickenpox; Child, Preschool; Fatal Outcome; Human

2001
Incidence of Reye's syndrome in France: a hospital-based survey.
    Journal of clinical epidemiology, 2001, Volume: 54, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Drug Labeling; France; Ho

2001
Reye's syndrome.
    Lancet (London, England), 2001, Jul-28, Volume: 358, Issue:9278

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Reproducibility of Results; Reye Sy

2001
[Incidence of Reye's syndrome in France].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2001, Volume: 8, Issue:11

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Hospitalized; Child, Pre

2001
Government sued for 11 week delay in warning about aspirin.
    BMJ (Clinical research ed.), 2002, Jan-19, Volume: 324, Issue:7330

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Female; Humans; Jurisprudence; Reye Syndrom

2002
Woman damaged by aspirin loses court claim.
    BMJ (Clinical research ed.), 2002, Feb-23, Volume: 324, Issue:7335

    Topics: Adult; Aspirin; Female; Government; Humans; Malpractice; Reye Syndrome; United Kingdom

2002
Reye's syndrome revisited. Outdated concept of Reye's syndrome was used.
    BMJ (Clinical research ed.), 2002, Mar-02, Volume: 324, Issue:7336

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Diagnosis, Differential; Humans; Reye Syndr

2002
Is aspirin a cause of Reye's syndrome? A case against.
    Drug safety, 2002, Volume: 25, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Incidence; Reye Syndrome; Risk Fact

2002
Aspirin and Reye's syndrome: is the response appropriate?
    Journal of clinical pharmacy and therapeutics, 2002, Volume: 27, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Reye Syndrome; Risk Ass

2002
[Severe Reye syndrome: report of 14 cases managed in a pediatric intensive care unit over 11 years].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2002, Volume: 9, Issue:6

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Edema; Child; Child, Preschoo

2002
Salicylate intoxication and influenza in ferrets.
    Pediatric research, 1979, Volume: 13, Issue:1

    Topics: Animals; Arginase; Argininosuccinate Lyase; Aspartate Aminotransferases; Aspirin; Carbamoyl-Phosphat

1979
Diagnostic criteria for influenza B-associated Reye's syndrome: clinical vs. pathologic criteria.
    Pediatrics, 1977, Volume: 60, Issue:5

    Topics: Acid-Base Imbalance; Ammonia; Aspirin; Humans; Hypoglycemia; Influenza, Human; Liver Function Tests;

1977
Influenza: the disease and its complications.
    Hospital practice, 1976, Volume: 11, Issue:12

    Topics: Amantadine; Aspirin; Bacterial Infections; Bronchitis; Central Nervous System Diseases; Cross Infect

1976
Acute liver failure and encephalopathy (Reye's syndrome?) during salicylate therapy.
    Acta paediatrica Scandinavica, 1975, Volume: 64, Issue:6

    Topics: Acute Disease; Adolescent; Aspirin; Brain Diseases; Chemical and Drug Induced Liver Injury; Female;

1975
Acute encephalopathy in siblings. Reye syndrome vs salicylate intoxication.
    American journal of diseases of children (1960), 1976, Volume: 130, Issue:3

    Topics: Aspirin; Brain; Brain Diseases; Child; Diagnosis, Differential; Female; Humans; Liver; Liver Disease

1976
Aspirin, acetaminophen and proton transport through phospholipid bilayers and mitochondrial membranes.
    Molecular and cellular biochemistry, 1992, Sep-08, Volume: 114, Issue:1-2

    Topics: Acetaminophen; Animals; Anions; Aspirin; Biological Transport; Humans; Hydrogen-Ion Concentration; I

1992
Reduction of deaths after drug labelling for risk of Reye's syndrome.
    Lancet (London, England), 1992, Oct-24, Volume: 340, Issue:8826

    Topics: Adolescent; Aspirin; Centers for Disease Control and Prevention, U.S.; Child; Drug Labeling; Humans;

1992
Ibuprofen safety.
    Pediatrics, 1992, Volume: 90, Issue:1 Pt 1

    Topics: Aspirin; Child; Fever; Humans; Ibuprofen; Reye Syndrome

1992
Aspirin use in children: heeding the warning?
    Australian journal of public health, 1992, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aspirin; Australia; Child; Child, Preschool; Drug Labeling; Female; Humans; Infan

1992
Experimental study on Reye's syndrome: inhibitory effect of interferon alfa on acetylsalicylate-induced injury to rat liver mitochondria.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:8

    Topics: Animals; Aspirin; Cytokines; Interferon-alpha; Male; Microscopy, Electron; Mitochondria, Liver; Oxyg

1992
Reye syndrome or side-effects of anti-emetics?
    European journal of pediatrics, 1991, Volume: 150, Issue:7

    Topics: Antiemetics; Aspirin; Basal Ganglia Diseases; Bias; Child; Cytomegalovirus Infections; Diagnosis, Di

1991
Induction of omega-oxidation of monocarboxylic acids in rats by acetylsalicylic acid.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:6

    Topics: Animals; Aspirin; Dicarboxylic Acids; Fatty Acids; In Vitro Techniques; Liver; Male; Oxidation-Reduc

1991
Reye's syndrome in adult with AIDS.
    Lancet (London, England), 1990, Jun-16, Volume: 335, Issue:8703

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aspirin; Female; Humans; Liver Function Tests; Reye Syndr

1990
Scientific standards of criticism: a reaction to "Scientific standards in epidemiologic studies of the menace of daily life," by A.R. Feinstein.
    Epidemiology (Cambridge, Mass.), 1990, Volume: 1, Issue:1

    Topics: Aspirin; Bias; Causality; Cohort Studies; Decision Making, Organizational; Epidemiologic Methods; Ep

1990
Treatment of viral pharyngitis or flu.
    BMJ (Clinical research ed.), 1990, Nov-17, Volume: 301, Issue:6761

    Topics: Adult; Aspirin; Child; Contraindications; Humans; Influenza, Human; Pharyngitis; Reye Syndrome; Viru

1990
Carnitine metabolism and urinary organic acid excretion in Reye's syndrome and salicylate intoxication.
    Acta paediatrica Japonica : Overseas edition, 1990, Volume: 32, Issue:4

    Topics: Aspirin; Carnitine; Child, Preschool; Dicarboxylic Acids; Fatty Acids; Female; Humans; Infant; Male;

1990
A catch in the Reye is awry.
    Cleveland Clinic journal of medicine, 1990, Volume: 57, Issue:4

    Topics: Adolescent; Age Factors; Aspirin; Australia; Child; Child, Preschool; Disease Outbreaks; Humans; Inf

1990
The metabolic effects of aspirin in fasting and fed subjects: relevance to the aetiology of Reye's syndrome.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:5

    Topics: 3-Hydroxybutyric Acid; Adult; Aspirin; Blood Glucose; Fasting; Food; Humans; Hydroxybutyrates; Lacta

1990
Trends in the incidence of Reye's syndrome and the use of aspirin.
    Archives of disease in childhood, 1990, Volume: 65, Issue:8

    Topics: Acetaminophen; Aspirin; Child; Child, Preschool; Female; Fever; Humans; Incidence; Infant; Male; Rey

1990
Depression of oxidative metabolism of aspirin in mice via an interferon-associated mechanism in relation to Reye's syndrome.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:3

    Topics: Animals; Aspirin; Interferons; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Newcastle diseas

1987
Reye syndrome surveillance--United States, 1987 and 1988.
    MMWR. Morbidity and mortality weekly report, 1989, May-12, Volume: 38, Issue:18

    Topics: Aspirin; Child; Child, Preschool; Diagnosis, Differential; Female; Hospitalization; Humans; Male; Po

1989
[Reye syndrome treated with valproic acid in association with varicella infection].
    Der Nervenarzt, 1989, Volume: 60, Issue:5

    Topics: Adult; Aspirin; Carbamazepine; Chickenpox; Drug Therapy, Combination; Epilepsy; Humans; Male; Reye S

1989
Survey of analgesic use.
    The Journal of the Royal College of General Practitioners, 1989, Volume: 39, Issue:319

    Topics: Aspirin; Health Education; Humans; Reye Syndrome

1989
Reye's syndrome and analgesic choice in dentistry.
    British dental journal, 1989, Nov-25, Volume: 167, Issue:10

    Topics: Acetaminophen; Aspirin; Attitude; Child; Child, Preschool; Female; Health Education; Humans; Infant;

1989
New epidemiologic evidence confirming that bias does not explain the aspirin/Reye's syndrome association.
    JAMA, 1989, May-05, Volume: 261, Issue:17

    Topics: Adolescent; Aspirin; Child; Child, Preschool; Data Collection; Epidemiologic Methods; Female; Hospit

1989
Reye's syndrome in an adult.
    Connecticut medicine, 1989, Volume: 53, Issue:1

    Topics: Adult; Age Factors; Aspirin; Diagnosis, Differential; Humans; Liver; Male; Reye Syndrome; Suicide

1989
Reye's syndrome and aspirin: epidemiological associations and inborn errors of metabolism.
    Lancet (London, England), 1987, Aug-22, Volume: 2, Issue:8556

    Topics: Amino Acid Metabolism, Inborn Errors; Aspirin; Child; Child, Preschool; Diagnosis, Differential; Hum

1987
Reye's syndrome and aspirin.
    Lancet (London, England), 1987, Oct-10, Volume: 2, Issue:8563

    Topics: Aspirin; Child, Preschool; Humans; Infant; Metabolism, Inborn Errors; Reye Syndrome

1987
Reye's syndrome and aspirin.
    Lancet (London, England), 1988, Sep-17, Volume: 2, Issue:8612

    Topics: Aspirin; Child; Diseases in Twins; Humans; Male; Reye Syndrome

1988
Reye's syndrome in children travelling abroad.
    Lancet (London, England), 1988, Nov-05, Volume: 2, Issue:8619

    Topics: Aspirin; Child; Humans; Male; Reye Syndrome; Travel

1988
Hepatic metabolic alterations in rats treated with low-dose endotoxin and aspirin: an animal model of Reye's syndrome.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:1

    Topics: Acyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aspirin; Disease Models, An

1989
Dispute over access to Reye's study data.
    Science (New York, N.Y.), 1985, Oct-18, Volume: 230, Issue:4723

    Topics: Aspirin; Centers for Disease Control and Prevention, U.S.; Child; Federal Government; Humans; Jurisp

1985
Aspirin and Reye syndrome: a saga unfolds.
    North Carolina medical journal, 1985, Volume: 46, Issue:12

    Topics: Adolescent; Aspirin; Centers for Disease Control and Prevention, U.S.; Child; Child, Preschool; Huma

1985
Reye's data to be turned over to company.
    Science (New York, N.Y.), 1986, Jan-10, Volume: 231, Issue:4734

    Topics: Aspirin; Centers for Disease Control and Prevention, U.S.; Child; Federal Government; Humans; Jurisp

1986
Reye's syndrome and aspirin.
    British medical journal (Clinical research ed.), 1986, Jun-14, Volume: 292, Issue:6535

    Topics: Adolescent; Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Humans; Infant; Infant, Newborn;

1986
Aspirin and Reye's syndrome.
    The Queensland nurse, 1986, Volume: 5, Issue:6

    Topics: Adolescent; Aspirin; Child; Humans; Reye Syndrome

1986
Reye syndrome surveillance--United States, 1986.
    MMWR. Morbidity and mortality weekly report, 1987, Oct-23, Volume: 36, Issue:41

    Topics: Adolescent; Adult; Aspirin; Child; Child, Preschool; Female; Humans; Infant; Influenza, Human; Male;

1987
A catch in 'a catch in the Reye'.
    Pediatrics, 1988, Volume: 82, Issue:4

    Topics: Aspirin; Child; Humans; Reye Syndrome; Risk Factors

1988
The changing epidemiology of Reye's syndrome in the United States: further evidence for a public health success.
    JAMA, 1988, Dec-02, Volume: 260, Issue:21

    Topics: Adolescent; Aspirin; Chickenpox; Child; Child, Preschool; Diagnosis, Differential; Humans; Infant; L

1988
Varicella-zoster immunoglobulin for patients with Kawasaki syndrome receiving daily aspirin.
    The Pediatric infectious disease journal, 1988, Volume: 7, Issue:10

    Topics: Aspirin; Chickenpox; Child; Humans; Immune Sera; Immunization, Passive; Mucocutaneous Lymph Node Syn

1988
[Acetylsalicylic acid and Reye's syndrome--is documentation relevant?].
    Lakartidningen, 1988, Oct-19, Volume: 85, Issue:42

    Topics: Aspirin; Child; Child, Preschool; Humans; Reye Syndrome

1988
Reye's syndrome among patients with juvenile rheumatoid arthritis.
    JAMA, 1988, Dec-16, Volume: 260, Issue:23

    Topics: Adolescent; Arthritis, Juvenile; Aspirin; Humans; Ohio; Reye Syndrome; Risk Factors

1988
[Reye's syndrome and salicylates].
    Revue medicale de la Suisse romande, 1988, Volume: 108, Issue:12

    Topics: Acetaminophen; Adolescent; Aspirin; Child; Humans; Reye Syndrome; Salicylates; Virus Diseases

1988
[New benefits of aspirin].
    Esencia Odontologica, 1988, Oct-15, Issue:29

    Topics: Aspirin; Cataract; Humans; Myocardial Infarction; Reye Syndrome

1988
Aspirin anticoagulation for mechanical heart valves and Reye's syndrome.
    The Journal of thoracic and cardiovascular surgery, 1988, Volume: 95, Issue:1

    Topics: Aspirin; Child; Heart Valve Prosthesis; Humans; Reye Syndrome; Thromboembolism

1988
[Reye syndrome in an adult].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1988, Volume: 77, Issue:1

    Topics: Adult; Age Factors; Aspirin; Female; Humans; Injections, Intravenous; Mitochondria, Liver; Reye Synd

1988
Molecular integrity of aspirin in relation to Reye's syndrome.
    The West Virginia medical journal, 1988, Volume: 84, Issue:5

    Topics: Adolescent; Aspirin; Child; Child, Preschool; Humans; Hydrogen-Ion Concentration; Hydrolysis; Infant

1988
Aspirin and Reye syndrome.
    Pediatrics, 1988, Volume: 82, Issue:1

    Topics: Aspirin; Child; Humans; Medical Records; Reye Syndrome

1988
Reye's syndrome and aspirin. Evidence for a dose-response effect.
    JAMA, 1988, Aug-05, Volume: 260, Issue:5

    Topics: Adolescent; Aspirin; Chickenpox; Child; Child, Preschool; Dose-Response Relationship, Drug; Humans;

1988
Reye study criticized.
    Pediatrics, 1988, Volume: 82, Issue:3

    Topics: Aspirin; Australia; Child; Child, Preschool; Humans; Infant; North America; Reye Syndrome

1988
Preadmission antipyretics in Reye's syndrome.
    Archives of disease in childhood, 1988, Volume: 63, Issue:7

    Topics: Acetaminophen; Adolescent; Aspirin; Child; Child, Preschool; Fever; Hospitalization; Humans; Infant;

1988
[Role of aspirin in the etiology of Reye's syndrome].
    Harefuah, 1987, Volume: 113, Issue:7-8

    Topics: Aspirin; Humans; Reye Syndrome

1987
Using aspirin to treat diarrhoea.
    Journal of diarrhoeal diseases research, 1987, Volume: 5, Issue:1

    Topics: Aspirin; Child; Diarrhea; Humans; Reye Syndrome

1987
Aspirin and Reye's syndrome--do parents know?
    The Journal of the Royal College of General Practitioners, 1987, Volume: 37, Issue:303

    Topics: Aspirin; Attitude to Health; Child; Female; Health Education; Humans; Male; Parents; Reye Syndrome

1987
[Acetylsalicylic acid and Reye's syndrome. A possibility in solving the problem?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1987, Feb-20, Volume: 107, Issue:5

    Topics: Aspirin; Humans; Reye Syndrome

1987
Aspirin use and Reye syndrome.
    Pediatrics, 1987, Volume: 79, Issue:6

    Topics: Aspirin; Child; Drug Utilization; Humans; Reye Syndrome; United States

1987
National patterns of aspirin use and Reye syndrome reporting, United States, 1980 to 1985.
    Pediatrics, 1987, Volume: 79, Issue:6

    Topics: Acetaminophen; Adult; Aspirin; Child; Drug Utilization; Humans; Middle Aged; Reye Syndrome; United S

1987
Reye's syndrome and aspirin.
    Journal of the Royal Society of Medicine, 1987, Volume: 80, Issue:5

    Topics: Aspirin; Humans; Reye Syndrome

1987
Leads from the MMWR. Reye syndrome surveillance--United States, 1986.
    JAMA, 1987, Nov-20, Volume: 258, Issue:19

    Topics: Adolescent; Adult; Aspirin; Child; Child, Preschool; Female; Humans; Infant; Influenza, Human; Male;

1987
Reye's syndrome and salicylates.
    JAMA, 1987, Dec-04, Volume: 258, Issue:21

    Topics: Academies and Institutes; Aspirin; Child; Data Collection; Drug Industry; Humans; Reye Syndrome; Uni

1987
A catch in the Reye.
    Pediatrics, 1987, Volume: 80, Issue:5

    Topics: Acetaminophen; Aspirin; Australia; Child; Child, Preschool; Female; Humans; Infant; Male; Retrospect

1987
Reye's syndrome and juvenile rheumatoid arthritis: a case report in Texas.
    Texas medicine, 1987, Volume: 83, Issue:10

    Topics: Arthritis, Juvenile; Aspirin; Child, Preschool; Humans; Male; Reye Syndrome

1987
PHS study finds strong association between aspirin use and Reye's syndrome.
    Clinical pharmacy, 1987, Volume: 6, Issue:7

    Topics: Aspirin; Child; Epidemiologic Methods; Humans; Reye Syndrome

1987
[Reye's syndrome in Spain, 1980-1984 (A cooperative study: Pediatric Intensive Care Section of the Asociación Española de Pediatría)].
    Anales espanoles de pediatria, 1986, Volume: 24, Issue:5

    Topics: Aspirin; Child; Child, Preschool; Humans; Infant; Retrospective Studies; Reye Syndrome; Societies, M

1986
Reye syndrome and aspirin therapy.
    American journal of diseases of children (1960), 1986, Volume: 140, Issue:10

    Topics: Acute Disease; Aspirin; Child; Female; Humans; Reye Syndrome; Rheumatic Fever

1986
[Reye's syndrome in children and the use of acetylsalicylic acid].
    Nederlands tijdschrift voor geneeskunde, 1986, Sep-06, Volume: 130, Issue:36

    Topics: Aspirin; Child; Europe; Humans; Influenza, Human; Reye Syndrome; Smallpox; United States; Virus Dise

1986
Reye's syndrome. An epidemiologic analysis of mild disease.
    American journal of diseases of children (1960), 1986, Volume: 140, Issue:12

    Topics: Acetaminophen; Ammonia; Aspirin; Bilirubin; Female; Humans; Male; Reye Syndrome

1986
A survey of aspirin use and Reye's syndrome awareness among parents.
    American journal of public health, 1986, Volume: 76, Issue:12

    Topics: Adult; Aspirin; Attitude to Health; Chickenpox; Data Collection; Female; Humans; Income; Influenza,

1986
Reye's syndrome in adults. A case report and review of the literature.
    Archives of internal medicine, 1986, Volume: 146, Issue:12

    Topics: Aspirin; Humans; Liver; Microscopy, Electron; Middle Aged; Mitochondria, Liver; Reye Syndrome

1986
Obtaining access to data from government-sponsored medical research.
    The New England journal of medicine, 1986, Dec-25, Volume: 315, Issue:26

    Topics: Aspirin; Confidentiality; Financing, Government; Humans; Jurisprudence; Research Support as Topic; R

1986
Reye's syndrome and aspirin: guilt by association.
    Irish medical journal, 1986, Volume: 79, Issue:10

    Topics: Aspirin; Child; Humans; Reye Syndrome

1986
Reye's syndrome in a boy treated with salicylates for Reiter's disease.
    Irish medical journal, 1986, Volume: 79, Issue:10

    Topics: Arthritis, Reactive; Aspirin; Child; Humans; Male; Reye Syndrome

1986
Reye's syndrome and aspirin.
    The Journal of the Royal College of General Practitioners, 1986, Volume: 36, Issue:290

    Topics: Aspirin; Child; Humans; Pharmacy and Therapeutics Committee; Reye Syndrome; United Kingdom

1986
[Acetylsalicylic acid and Reye's syndrome].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1986, Nov-10, Volume: 106, Issue:31

    Topics: Aspirin; Humans; Reye Syndrome

1986
Use of aspirin and Reye's syndrome.
    American journal of diseases of children (1960), 1987, Volume: 141, Issue:3

    Topics: Acetaminophen; Aspirin; Child; Fever; Humans; Reye Syndrome

1987
Public Health Service study of Reye's syndrome and medications. Report of the main study.
    JAMA, 1987, Apr-10, Volume: 257, Issue:14

    Topics: Adolescent; Aspirin; Child; Child, Preschool; Epidemiologic Methods; Female; Humans; Male; Research

1987
Response of epithelial cells of the choroid plexus in the ferret model for Reye's syndrome.
    Laboratory investigation; a journal of technical methods and pathology, 1987, Volume: 56, Issue:3

    Topics: Animals; Aspirin; Choroid Plexus; Disease Models, Animal; Epithelium; Ferrets; Male; Microscopy, Ele

1987
[Acetylsalicylic acid and Reye's syndrome].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1987, Jan-10, Volume: 107, Issue:1

    Topics: Aspirin; Child; Child, Preschool; Diagnosis, Differential; Humans; Reye Syndrome

1987
Fever: to treat or not to treat.
    Rational drug therapy, 1985, Volume: 19, Issue:12

    Topics: Acetaminophen; Aspirin; Child; Fever; Humans; Ibuprofen; Interleukin-1; Reye Syndrome

1985
Decreasing trends in Reye syndrome and aspirin use in Michigan, 1979 to 1984.
    Pediatrics, 1986, Volume: 77, Issue:1

    Topics: Acetaminophen; Aspirin; Child; Common Cold; Fever; Humans; Michigan; Reye Syndrome

1986
Aspirin and Reye's syndrome: the change in prescribing habits of health professionals.
    Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:2

    Topics: Acetaminophen; Aspirin; Child; Drug Prescriptions; Drug Utilization; Humans; Ohio; Reye Syndrome; Su

1986
Reye's syndrome and salicylates.
    The New England journal of medicine, 1986, Apr-03, Volume: 314, Issue:14

    Topics: Aspirin; Child; Humans; Pilot Projects; Research Design; Reye Syndrome

1986
Changing epidemiology of Reye syndrome in the United States.
    Pediatrics, 1986, Volume: 77, Issue:4

    Topics: Adolescent; Age Factors; Aspirin; Child; Child, Preschool; Humans; Infant; Influenza, Human; Populat

1986
Kawasaki syndrome, Reye syndrome, and aspirin.
    Pediatrics, 1986, Volume: 77, Issue:4

    Topics: Aspirin; Child; Child, Preschool; Humans; Mucocutaneous Lymph Node Syndrome; Reye Syndrome; Risk

1986
Study of Reye's-aspirin link raises concerns.
    Science (New York, N.Y.), 1985, Jan-25, Volume: 227, Issue:4685

    Topics: Adolescent; Aspirin; Chickenpox; Child; Humans; Influenza, Human; Pilot Projects; Reye Syndrome

1985
Acute hemorrhagic, hepatic, and neurologic manifestations in juvenile rheumatoid arthritis: possible relationship to drugs or infection.
    The Journal of pediatrics, 1985, Volume: 106, Issue:4

    Topics: Acute Disease; Arthritis, Juvenile; Aspirin; Bacterial Infections; Child; Child, Preschool; Coma; Di

1985
Antipyretic use among children during the 1983 influenza season.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Aspirin; Chickenpox; Child; Child, Preschool; Female; Fever; Healt

1985
Confirmation of serum salicylate levels in Reye's syndrome: a comparison between the Natelson colorimetric method and high performance liquid chromatography.
    Clinica chimica acta; international journal of clinical chemistry, 1985, Feb-15, Volume: 145, Issue:3

    Topics: Ammonia; Aspirin; Child; Chromatography, High Pressure Liquid; Colorimetry; Humans; Reye Syndrome; S

1985
[Reye's syndrome and the administration of acetylsalicylic acid in children].
    Boletin medico del Hospital Infantil de Mexico, 1985, Volume: 42, Issue:6

    Topics: Aspirin; Child; Fatty Liver; Humans; Liver; Muscles; Reye Syndrome; Virus Diseases

1985
Reye's syndrome in British Columbia.
    Canadian Medical Association journal, 1985, Aug-15, Volume: 133, Issue:4

    Topics: Adolescent; Aspirin; British Columbia; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Inf

1985
The ferret as a model for inner ear research.
    Laboratory animal science, 1985, Volume: 35, Issue:3

    Topics: Animals; Animals, Laboratory; Arginine; Aspirin; Carnivora; Disease Models, Animal; Ear, Inner; Ferr

1985
Management of Reye's syndrome: need for early diagnosis and intravenous treatment of stage I non-comatose cases.
    Pediatric annals, 1985, Volume: 14, Issue:7

    Topics: Aspirin; Chickenpox; Coma; Glucose; Humans; Influenza, Human; Infusions, Parenteral; Reye Syndrome

1985
Reye syndrome associated with aspirin therapy for systemic lupus erythematosus.
    Pediatrics, 1985, Volume: 76, Issue:2

    Topics: Adolescent; Ammonia; Aspartate Aminotransferases; Aspirin; Biopsy, Needle; Electroencephalography; F

1985
[Reye's syndrome--visceral fatty degeneration and encephalopathy].
    Duodecim; laaketieteellinen aikakauskirja, 1985, Volume: 101, Issue:14

    Topics: Aspirin; Brain; Child; Fatty Liver; Humans; Reye Syndrome; Virus Diseases

1985
Aspirin in juvenile rheumatoid arthritis.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:9

    Topics: Arthritis, Juvenile; Aspirin; Humans; Reye Syndrome

1985
Reye syndrome and juvenile rheumatoid arthritis in Michigan.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:9

    Topics: Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Female; Humans; Male; Michigan; Reye Syndrome

1985
Influenza B virus model of Reye's syndrome in mice: the effect of aspirin.
    Annals of neurology, 1985, Volume: 18, Issue:5

    Topics: Animals; Aspartate Aminotransferases; Aspirin; Brain; Disease Models, Animal; Dose-Response Relation

1985
Reye syndrome update.
    FDA drug bulletin, 1985, Volume: 15, Issue:4

    Topics: Aspirin; Health Education; Humans; Reye Syndrome; Salicylates; United States; United States Food and

1985
Reye's syndrome and hyperaminoacidemia.
    The Journal of pediatrics, 1974, Volume: 84, Issue:3

    Topics: Amino Acids; Aspirin; Brain Diseases; Child; Child, Preschool; Diagnosis, Differential; Fatty Liver;

1974