Page last updated: 2024-10-23

aspirin and Facial Pain

aspirin has been researched along with Facial Pain in 13 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Facial Pain: Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.

Research Excerpts

ExcerptRelevanceReference
"Maxillofacial pain is often managed by the use of mild analgesics, such as acetylsalicylic acid and nonsteroidal anti-inflammatory agents."5.27Aspirin-intolerance syndrome. Report of a case. ( Fridrich, HH; Fridrich, KL; Zach, GA, 1986)
"Osteoid osteoma is a benign tumor of bone characterized by pain, usually occurring at night, that shows a dramatic response to aspirin."3.74Osteoid osteoma of the zygoma: report of an unusual case. ( Mintz, S; Velez, I, 2007)
"Patients with chronic facial pain including those with facial arthromyalgia (TMJ dysfunction syndrome) were investigated for evidence of abnormal systemic and intra-articular free radical activity."1.30The role of oxygen free radicals in idiopathic facial pain. ( Aghabeigi, B; Haque, M; Harris, M; Henderson, B; Hodges, SJ; Wasil, M, 1997)
"Maxillofacial pain is often managed by the use of mild analgesics, such as acetylsalicylic acid and nonsteroidal anti-inflammatory agents."1.27Aspirin-intolerance syndrome. Report of a case. ( Fridrich, HH; Fridrich, KL; Zach, GA, 1986)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's6 (46.15)18.2507
2000's3 (23.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Polat, O1
Karaman, AI1
Arias, OR1
Marquez-Orozco, MC1
Mintz, S1
Velez, I1
Preshaw, PM1
Meechan, JG1
Dodd, MD1
Hasegawa, TK1
Matthews, M1
Gage, T1
Ngan, P1
Wilson, S1
Shanfeld, J1
Amini, H1
Aghabeigi, B1
Haque, M1
Wasil, M1
Hodges, SJ1
Henderson, B1
Harris, M1
Sanges, G1
Sampaolo, S1
Di Iorio, G1
List, T1
Helkimo, M1
Andersson, S1
Carlsson, GE1
Clavelou, P1
Pajot, J1
Dallel, R1
Raboisson, P1
Hargreaves, KM1
Troullos, ES1
Dionne, RA1
Fukuda, Y1
Izumikawa, K1
Fridrich, HH1
Zach, GA1
Fridrich, KL1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Photobiomodulation on Pain During Orthodontic Treatment[NCT05361616]50 participants (Anticipated)Interventional2023-04-17Recruiting
Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain of Initial Orthodontic Wire Insertion: a Randomized Controlled Trial[NCT04059172]Early Phase 1375 participants (Anticipated)Interventional2019-12-10Recruiting
Assessment of Preemptive Analgesic Effect of CaldolorĀ® vs. OfirmevĀ® on Third Molar Surgery: A Prospective, Randomized, Double-blinded Clinical Trial[NCT02133326]Phase 267 participants (Actual)Interventional2014-03-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aspirin and Facial Pain

ArticleYear
Pharmacologic rationale for the treatment of acute pain.
    Dental clinics of North America, 1987, Volume: 31, Issue:4

    Topics: Acute Disease; Analgesics; Aspirin; Facial Pain; Humans; Nociceptors; Toothache

1987

Trials

3 trials available for aspirin and Facial Pain

ArticleYear
Pain control during fixed orthodontic appliance therapy.
    The Angle orthodontist, 2005, Volume: 75, Issue:2

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents,

2005
The effect of ibuprofen on the level of discomfort in patients undergoing orthodontic treatment.
    American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 1994, Volume: 106, Issue:1

    Topics: Adolescent; Analysis of Variance; Aspirin; Chi-Square Distribution; Double-Blind Method; Facial Pain

1994
Acupuncture and occlusal splint therapy in the treatment of craniomandibular disorders. Part I. A comparative study.
    Swedish dental journal, 1992, Volume: 16, Issue:4

    Topics: Acetaminophen; Activities of Daily Living; Acupuncture Therapy; Adult; Aged; Aspirin; Craniomandibul

1992

Other Studies

9 other studies available for aspirin and Facial Pain

ArticleYear
Aspirin, acetaminophen, and ibuprofen: their effects on orthodontic tooth movement.
    American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 2006, Volume: 130, Issue:3

    Topics: Acetaminophen; Alveolar Bone Loss; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Anti-Inf

2006
Osteoid osteoma of the zygoma: report of an unusual case.
    Journal of the American Dental Association (1939), 2007, Volume: 138, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Facial Pain; Humans; Male; Middle Aged; Osteoma, O

2007
Self-medication for the control of dental pain: what are our patients taking?
    Dental update, 1994, Volume: 21, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Aspirin; Chi-Square Distribution; Codeine; Consu

1994
What would you do? "The pain is really bad and I need something (Percodan) now.".
    Texas dental journal, 1994, Volume: 111, Issue:3

    Topics: Acute Disease; Analgesics, Opioid; Aspirin; Caffeine; Drug Combinations; Ethics, Dental; Facial Pain

1994
The role of oxygen free radicals in idiopathic facial pain.
    The British journal of oral & maxillofacial surgery, 1997, Volume: 35, Issue:3

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies;

1997
Craniofacial pain followed by scalp necrosis and stroke. An unusual presentation of the primary antiphospholipid syndrome.
    Journal of neurology, 1999, Volume: 246, Issue:2

    Topics: Aged; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Autoimmune D

1999
Application of the formalin test to the study of orofacial pain in the rat.
    Neuroscience letters, 1989, Sep-11, Volume: 103, Issue:3

    Topics: Acetaminophen; Animals; Aspirin; Facial Pain; Formaldehyde; Injections, Intraperitoneal; Injections,

1989
Intravenous aspirin for intractable headache and facial pain.
    Headache, 1988, Volume: 28, Issue:1

    Topics: Adult; Aspirin; Facial Pain; Headache; Humans; Infusions, Intravenous; Middle Aged

1988
Aspirin-intolerance syndrome. Report of a case.
    Oral surgery, oral medicine, and oral pathology, 1986, Volume: 61, Issue:5

    Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Facial Pain; Humans; Male; Nasal Polyps; Syndrome

1986