Page last updated: 2024-10-23

aspirin and Experimental Neoplasms

aspirin has been researched along with Experimental Neoplasms in 48 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Aspirin has been proposed in recent years as a candidate for chemoprevention of adenocarcinoma in patients with Barrett's esophagus."7.80Effect of aspirin treatment on the prevention of esophageal adenocarcinoma in a rat experimental model. ( Cebrián, C; Esquivias, P; García-González, MA; Lanas, A; Morandeira, A; Ortego, J; Piazuelo, E; Santander, S, 2014)
"Luteolin (LUT) has cancer prevention and anti-inflammatory effects."5.42Luteolin supplementation adjacent to aspirin treatment reduced dimethylhydrazine-induced experimental colon carcinogenesis in rats. ( Ahmed, ES; El-Waseef, AM; Osman, NH; Said, UZ, 2015)
" Combination therapy may produce synergic effects with better tumor inhibition as well as lower dosage or side affects."5.31[Effects of combination of octreotide and aspirin on proliferation of human hepatocellular carcinoma]. ( Tang, CW; Tang, LP; Wang, CH, 2002)
" This study investigated the protective role of ASA in azoxymethane (AOM)-initiated and dextran sulfate sodium (DSS)-promoted colitis-associated colon cancer (CAC) and examined the epigenetic effects, particularly on histone 3 lysine 27 acetylation (H3K27ac), underlying the preventive effect of ASA."3.83The epigenetic effects of aspirin: the modification of histone H3 lysine 27 acetylation in the prevention of colon carcinogenesis in azoxymethane- and dextran sulfate sodium-treated CF-1 mice. ( Guo, Y; Huang, MT; Kong, AN; Li, W; Liu, Y; Su, ZY; Zhang, C, 2016)
"Aspirin has been proposed in recent years as a candidate for chemoprevention of adenocarcinoma in patients with Barrett's esophagus."3.80Effect of aspirin treatment on the prevention of esophageal adenocarcinoma in a rat experimental model. ( Cebrián, C; Esquivias, P; García-González, MA; Lanas, A; Morandeira, A; Ortego, J; Piazuelo, E; Santander, S, 2014)
" In this work, we tested the ability of aspirin to activate the AKT survival pathway in methylcholanthrene-induced fibrosarcoma cells (Meth A) transplanted into BALB/c nude mice and the clinical effect of aspirin cotreatment during etoposide (VP-16)-based anticancer therapy."3.73Aspirin reduces the outcome of anticancer therapy in Meth A-bearing mice through activation of AKT-glycogen synthase kinase signaling. ( Acquaviva, AM; Acquaviva, F; Di Matola, T; di Palma, A; Leone, V; Matarese, G; Ricchi, P, 2006)
"The aim of this study is to assess the role of high fibre diet and aspirin on dimethylhydrazine (DMH)-induced colorectal cancer in rats."3.72The effect of aspirin and high fibre diet on colorectal carcinoma: a comparative experimental study. ( Kiskinis, D; Miliaras, D; Miliaras, S; Vrettou, E; Zavitsanakis, A, 2004)
"The growth rate (studied by mean tumor dry weight) and vascularization (studied by microangiography) of two transplantable rat tumors, a 20-methylcholanthrene-induced fibrosarcoma and a hepatoma, were significantly reduced by three prostaglandin synthesis inhibitors, indomethacin, diclofenac-sodium and aspirin, irrespective of whether the drugs were administered early or late during tumor growth."3.66Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat. ( Peterson, HI, 1983)
" The effects of warfarin, aspirin and heparin administration on the early arrest patterns of 125IdUrd-labelled TA3 carcinoma and Gardner lymphosarcoma cells injected intravenously into tumor-bearing mice were examined."3.66Initial tumor cell arrest in animals of defined coagulative status. ( Glaves, D; Weiss, L, 1978)
"In lay terms "cancers follow bleeding", which seems to be true for antithrombotic agents in general."2.52Solid cancers after antiplatelet therapy: Confirmations, controversies, and challenges. ( Cabrera-Fuentes, HA; Cherepanov, V; Kim, MH; Serebruany, VL, 2015)
"UVR promotes skin cancer through multiple mechanisms, including induction of inflammation, oxidative stress, and DNA damage such as 8-oxoguanine and cyclobutane pyrimidine dimers."1.62Aspirin Protects Melanocytes and Keratinocytes against UVB-Induced DNA Damage In Vivo. ( Boucher, KM; Burd, CE; Florell, SR; Grossman, D; Kumar, D; Liu, T; Lum, D; Okwundu, N; Rahman, H; VanBrocklin, MW, 2021)
" In this work, we reported a novel kind of BiOI@CuS nanoparticle to achieve safe and effective therapy of lung cancer by co-loading hydrochloric acid doxorubicin (DOX) and aspirin phenacetin and caffeine (APC)."1.51Construction of DOX/APC co-loaded BiOI@CuS NPs for safe and highly effective CT imaging and chemo-photothermal therapy of lung cancer. ( Cheng, J; He, D; Huang, G; Li, W; Wang, R; Zhang, Y; Zhu, J, 2019)
"However, postsurgical metastasis poses an immense setback in cancer therapy."1.51Minimal dosing of leukocyte targeting TRAIL decreases triple-negative breast cancer metastasis following tumor resection. ( Himmel, LE; Jyotsana, N; King, MR; Yu, F; Zhang, Z, 2019)
"1-Pyrene methanol was utilize to synthesize the anti-inflammatory prodrug pyrene-aspirin (P-aspirin) with a cleavable ester bond and also facilitate loading the prodrug on gold nanorod (AuNR)-encapsulated graphitic nanocapsule (AuNR@G), a photothermal agent, through π-π interactions."1.48Simultaneous Application of Photothermal Therapy and an Anti-inflammatory Prodrug using Pyrene-Aspirin-Loaded Gold Nanorod Graphitic Nanocapsules. ( Chen, L; Chen, Z; Dong, Q; Hu, X; Song, L; Tan, W; Wang, X; Xiao, L; Xu, M; Zhang, L; Zou, Y, 2018)
" The two NSAIDs proved to be safe and efficacious in the experimental model used."1.43Selective inhibition by aspirin and naproxen of mainstream cigarette smoke-induced genotoxicity and lung tumors in female mice. ( Balansky, R; D'Oria, C; De Flora, S; Ganchev, G; Iltcheva, M; La Maestra, S; Micale, RT; Steele, VE, 2016)
"Luteolin (LUT) has cancer prevention and anti-inflammatory effects."1.42Luteolin supplementation adjacent to aspirin treatment reduced dimethylhydrazine-induced experimental colon carcinogenesis in rats. ( Ahmed, ES; El-Waseef, AM; Osman, NH; Said, UZ, 2015)
"NOSH-aspirin is a potent anti-inflammatory, preferentially affecting cancer cells and targets parameters important in determining cellular mass."1.42Utility Of Nitric Oxide And Hydrogen Sulfide-Releasing Chimeras As Anticancer Agents. ( Kashfi, K, 2015)
" We investigated the long-term administration of low dose of aspirin in a model of experimental colon carcinogenesis in rats."1.36Long-term administration of aspirin inhibits tumour formation and triggers anti-neoplastic molecular changes in a pre-clinical model of colon carcinogenesis. ( Bouhadjar, M; Bousserouel, S; Gosse, F; Marescaux, J; Raul, F; Soler, L, 2010)
" Combination therapy may produce synergic effects with better tumor inhibition as well as lower dosage or side affects."1.31[Effects of combination of octreotide and aspirin on proliferation of human hepatocellular carcinoma]. ( Tang, CW; Tang, LP; Wang, CH, 2002)
"Pulmonary metastases with CT26 cells could be inhibited by induction of thrombocytopenia, and reconstituted by infusion of either murine or human platelets."1.27Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo. ( Ambrogio, C; Coller, BS; Karpatkin, S; Pearlstein, E, 1988)
"Indomethacin was able to reduce the levels of prostaglandin E (PGE) in the tumor tissue."1.26Inhibition of murine tumor growth and prostaglandin synthesis by indomethacin. ( Fulton, AM; Levy, JG, 1980)
"Aspirin treatment, 150 mg/kg twice daily, inhibited growth of a transplantable mast-cell ascites tumor (P815) by 39-43% (p less than 0."1.26Alteration of tumor growth by aspirin and indomethacin: studies with two transplantable tumors in mouse. ( Beaven, MA; Hial, V; Horakova, Z; Shaff, FE, 1976)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199024 (50.00)18.7374
1990's4 (8.33)18.2507
2000's5 (10.42)29.6817
2010's14 (29.17)24.3611
2020's1 (2.08)2.80

Authors

AuthorsStudies
Youssif, BGM1
Abdelrahman, MH1
Abdelazeem, AH1
Abdelgawad, MA1
Ibrahim, HM1
Salem, OIA1
Mohamed, MFA1
Treambleau, L1
Bukhari, SNA1
Lu, S1
Obianom, ON1
Ai, Y1
Kumar, VL1
Verma, S1
Das, P1
Zhang, Y1
Wang, R1
Li, W2
Huang, G1
Zhu, J1
Cheng, J1
He, D1
Rahman, H1
Kumar, D1
Liu, T1
Okwundu, N1
Lum, D1
Florell, SR1
Burd, CE1
Boucher, KM1
VanBrocklin, MW1
Grossman, D1
Dong, Q1
Wang, X1
Hu, X1
Xiao, L1
Zhang, L1
Song, L1
Xu, M1
Zou, Y1
Chen, L1
Chen, Z1
Tan, W1
Jyotsana, N1
Zhang, Z1
Himmel, LE1
Yu, F1
King, MR1
Esquivias, P1
Cebrián, C1
Morandeira, A1
Santander, S1
Ortego, J1
García-González, MA1
Lanas, A1
Piazuelo, E1
Osman, NH1
Said, UZ1
El-Waseef, AM1
Ahmed, ES1
Balansky, R1
Ganchev, G1
Iltcheva, M1
Micale, RT1
La Maestra, S1
D'Oria, C1
Steele, VE1
De Flora, S1
Serebruany, VL1
Cherepanov, V1
Cabrera-Fuentes, HA1
Kim, MH1
Gao, M1
Kong, Q1
Hua, H1
Yin, Y1
Wang, J1
Luo, T1
Jiang, Y1
Guo, Y1
Liu, Y1
Zhang, C1
Su, ZY1
Huang, MT1
Kong, AN1
Kashfi, K1
Bousserouel, S1
Gosse, F1
Bouhadjar, M1
Soler, L1
Marescaux, J1
Raul, F1
Tang, CW1
Tang, LP1
Wang, CH1
Bair, WB1
Hart, N1
Einspahr, J1
Liu, G1
Dong, Z1
Alberts, D1
Bowden, GT1
BLANPIN, O1
Miliaras, S1
Miliaras, D1
Vrettou, E1
Zavitsanakis, A1
Kiskinis, D1
di Palma, A1
Matarese, G1
Leone, V1
Di Matola, T1
Acquaviva, F1
Acquaviva, AM1
Ricchi, P1
Kunita, A1
Kashima, TG1
Morishita, Y1
Fukayama, M1
Kato, Y1
Tsuruo, T1
Fujita, N1
Peterson, HI1
Fulton, AM1
Levy, JG1
Chang, TH1
Lee, YC1
Lee, KY1
Sun, CH1
Chang, YP1
Cohen, SM1
Zenser, TV1
Murasaki, G1
Fukushima, S1
Mattammal, MB1
Rapp, NS1
Davis, BB1
Perkins, TM1
Shklar, G1
Hara, Y1
Steiner, M1
Baldini, MG1
Tessitore, L1
Costelli, P1
Baccino, FM1
Barnes, CJ1
Lee, M1
Hardman, WE1
Cameron, IL1
Rioux, N1
Castonguay, A1
Hilgard, P3
Heller, H1
Schmidt, CG1
Glaves, D1
Weiss, L1
Droller, MJ1
Perlmann, P1
Schneider, MU1
Grinwich, KD1
Plescia, OJ1
Thornes, RD1
Pollard, M1
Chang, CF1
Luckert, PH1
Cattan, A1
Pourny, C1
Carpentier, Y1
Cattan, E1
Barouh, M1
Hial, V1
Horakova, Z1
Shaff, FE1
Beaven, MA1
Shparyk, IaV1
Hart, DA1
Karpatkin, S1
Pearlstein, E1
Ambrogio, C1
Coller, BS1
Kolenich, JJ1
Mansour, EG1
Flynn, A1
Gasic, GJ1
Gasic, TB1
Murphy, S1
Wood, S1
Apps, MC1
Cater, DB1
Jaffe, BM1
Frohberg, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Randomized Control Trial of the Effect of Sorafenib Combined With Aspirin in Preventing the Recurrence in High-risk Patients With Hepatocellular Carcinoma[NCT02748304]52 participants (Actual)Interventional2016-04-30Terminated (stopped due to The enrollment of this study was slow. With the approval of lenvatinib in HCC,many patients choose the new drug, so subsequent enrollment may be more difficult.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for aspirin and Experimental Neoplasms

ArticleYear
Solid cancers after antiplatelet therapy: Confirmations, controversies, and challenges.
    Thrombosis and haemostasis, 2015, Nov-25, Volume: 114, Issue:6

    Topics: Adenosine; Animals; Anticarcinogenic Agents; Aspirin; Blood Platelets; Carcinogenicity Tests; Clopid

2015
Anticoagulants in the treatment of cancer.
    European journal of cancer, 1976, Volume: 12, Issue:10

    Topics: Ancrod; Animals; Anticoagulants; Aspirin; Coumarins; Factor XIII; Fibrinolytic Agents; Heparin; Huma

1976
[Indomethacin as a modulator of the activity of natural killer cells (a review of the literature)].
    Vrachebnoe delo, 1990, Issue:8

    Topics: Adjuvants, Immunologic; Animals; Aspirin; Cells, Cultured; Drug Synergism; Humans; Indomethacin; Kil

1990
Prostaglandins and cancer: an update.
    Prostaglandins, 1974, Jun-25, Volume: 6, Issue:6

    Topics: Animals; Aspirin; Bucladesine; Calcium; Carcinoma; Cell Division; Cell Line; Depression, Chemical; H

1974
[Present position of the toxicology of drugs].
    Munchener medizinische Wochenschrift (1950), 1970, Aug-28, Volume: 112, Issue:35

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amantadine; Aminopterin; Animals; Animals, Newbo

1970

Other Studies

43 other studies available for aspirin and Experimental Neoplasms

ArticleYear
Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2-a]indol-1(2H)-ones as potential anticancer agents effecting the reactive oxygen species production.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell Proliferation; Cell Survival; D

2018
Novel cinnamaldehyde-based aspirin derivatives for the treatment of colorectal cancer.
    Bioorganic & medicinal chemistry letters, 2018, 09-15, Volume: 28, Issue:17

    Topics: Acrolein; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Cell Cycle Checkpoints; Cell Line, Tum

2018
Artesunate suppresses inflammation and oxidative stress in a rat model of colorectal cancer.
    Drug development research, 2019, Volume: 80, Issue:8

    Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Anti-Inflammatory Agents; Antineoplastic Agent

2019
Construction of DOX/APC co-loaded BiOI@CuS NPs for safe and highly effective CT imaging and chemo-photothermal therapy of lung cancer.
    Journal of materials chemistry. B, 2019, 12-07, Volume: 7, Issue:45

    Topics: A549 Cells; Animals; Antibiotics, Antineoplastic; Aspirin; Bismuth; Caffeine; Cell Proliferation; Ce

2019
Aspirin Protects Melanocytes and Keratinocytes against UVB-Induced DNA Damage In Vivo.
    The Journal of investigative dermatology, 2021, Volume: 141, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Models, Animal; DNA Damage; Kerat

2021
Simultaneous Application of Photothermal Therapy and an Anti-inflammatory Prodrug using Pyrene-Aspirin-Loaded Gold Nanorod Graphitic Nanocapsules.
    Angewandte Chemie (International ed. in English), 2018, 01-02, Volume: 57, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Combined Modality Therapy; Gold; Graphite; HeLa Cells; H

2018
Minimal dosing of leukocyte targeting TRAIL decreases triple-negative breast cancer metastasis following tumor resection.
    Science advances, 2019, Volume: 5, Issue:7

    Topics: Animals; Apoptosis; Aspirin; Cell Line, Tumor; Cell Proliferation; Curcumin; Dioxolanes; E-Selectin;

2019
Effect of aspirin treatment on the prevention of esophageal adenocarcinoma in a rat experimental model.
    Oncology reports, 2014, Volume: 31, Issue:6

    Topics: Adenocarcinoma; Animals; Aspirin; Barrett Esophagus; Dinoprostone; Disease Models, Animal; Esophagea

2014
Luteolin supplementation adjacent to aspirin treatment reduced dimethylhydrazine-induced experimental colon carcinogenesis in rats.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Aspirin; Carcinoembryonic Ant

2015
Selective inhibition by aspirin and naproxen of mainstream cigarette smoke-induced genotoxicity and lung tumors in female mice.
    Archives of toxicology, 2016, Volume: 90, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Aspirin; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitor

2016
AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin.
    Oncotarget, 2016, Mar-29, Volume: 7, Issue:13

    Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Ag

2016
The epigenetic effects of aspirin: the modification of histone H3 lysine 27 acetylation in the prevention of colon carcinogenesis in azoxymethane- and dextran sulfate sodium-treated CF-1 mice.
    Carcinogenesis, 2016, Volume: 37, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Aspirin; Azoxymethane; Colitis; Colonic Neoplasms; Cyclooxygenase

2016
Utility Of Nitric Oxide And Hydrogen Sulfide-Releasing Chimeras As Anticancer Agents.
    Redox biology, 2015, Volume: 5

    Topics: Animals; Antineoplastic Agents; Aspirin; Disulfides; Humans; MCF-7 Cells; Mice; Neoplasms, Experimen

2015
Long-term administration of aspirin inhibits tumour formation and triggers anti-neoplastic molecular changes in a pre-clinical model of colon carcinogenesis.
    Oncology reports, 2010, Volume: 23, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Azoxymethane; Carc

2010
[Effects of combination of octreotide and aspirin on proliferation of human hepatocellular carcinoma].
    Ai zheng = Aizheng = Chinese journal of cancer, 2002, Volume: 21, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Carcinoma, Hepatocellular; Cell Di

2002
Inhibitory effects of sodium salicylate and acetylsalicylic acid on UVB-induced mouse skin carcinogenesis.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:12

    Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Aspirin; Biopsy, Needle; Cell Transformat

2002
[KAOLIN- AND ACETYLSALICYLIC ACID-INDUCED EDEMA IN THE CANCEROUS RAT].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Oct-05, Volume: 157

    Topics: Aspirin; Drug Hypersensitivity; Edema; Kaolin; Neoplasms; Neoplasms, Experimental; Pharmacology; Rat

1963
The effect of aspirin and high fibre diet on colorectal carcinoma: a comparative experimental study.
    Techniques in coloproctology, 2004, Volume: 8 Suppl 1

    Topics: Animals; Aspirin; Chi-Square Distribution; Colorectal Neoplasms; Dietary Fiber; Dimethylhydrazines;

2004
Aspirin reduces the outcome of anticancer therapy in Meth A-bearing mice through activation of AKT-glycogen synthase kinase signaling.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Aspirin; Etopos

2006
The platelet aggregation-inducing factor aggrus/podoplanin promotes pulmonary metastasis.
    The American journal of pathology, 2007, Volume: 170, Issue:4

    Topics: Animals; Aspirin; Blotting, Western; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Female; Flow

2007
Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat.
    Invasion & metastasis, 1983, Volume: 3, Issue:3

    Topics: Animals; Aspirin; Diclofenac; Fibrosarcoma; Indomethacin; Liver Neoplasms, Experimental; Neoplasm Tr

1983
Inhibition of murine tumor growth and prostaglandin synthesis by indomethacin.
    International journal of cancer, 1980, Nov-15, Volume: 26, Issue:5

    Topics: Animals; Aspirin; Female; Humans; Immunosuppressive Agents; Indomethacin; Mice; Neoplasm Transplanta

1980
Cocarcinogenic action of aspirin on gastric tumors induced by N-nitroso-N-methylnitroguanidine in rats.
    Journal of the National Cancer Institute, 1983, Volume: 70, Issue:6

    Topics: Adenocarcinoma; Animals; Aspirin; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Humans; Male;

1983
Aspirin inhibition of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced lesions of the urinary bladder correlated with inhibition of metabolism by bladder prostaglandin endoperoxide synthetase.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Animals; Aspirin; Biotransformation; Cyclooxygenase Inhibitors; FANFT; Hyperplasia; Male; Neoplasms,

1981
Delay in hamster buccal pouch carcinogenesis by aspirin and indomethacin.
    Oral surgery, oral medicine, and oral pathology, 1982, Volume: 53, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Aspirin; Carcinoma, Squamous Cell;

1982
Characterization of the platelet-aggregating activity of tumor cells.
    Cancer research, 1980, Volume: 40, Issue:4

    Topics: Adenocarcinoma; Adenosine Diphosphate; Animals; Aspirin; Cell Line; Cell Membrane; Growth Substances

1980
Pharmacological interference with tissue hypercatabolism in tumour-bearing rats.
    The Biochemical journal, 1994, Apr-01, Volume: 299 ( Pt 1)

    Topics: Adrenalectomy; Animals; Aspirin; Blood Glucose; Body Weight; Cachexia; Cathepsin D; Cholesterol; End

1994
Aspirin suppresses 1,2-dimethylhydrazine-induced alteration of proliferative parameters in rat colonic crypts.
    Cell proliferation, 1996, Volume: 29, Issue:8

    Topics: 1,2-Dimethylhydrazine; Animals; Aspirin; Cell Division; Dimethylhydrazines; Intestinal Mucosa; Male;

1996
Inhibitors of lipoxygenase: a new class of cancer chemopreventive agents.
    Carcinogenesis, 1998, Volume: 19, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Arachidonic Acid; Aspirin; Body Weight; Carcinogens; Drug Screenin

1998
Anti-inflammatory drugs and tumour growth.
    Lancet (London, England), 1979, Feb-24, Volume: 1, Issue:8113

    Topics: Animals; Aspirin; Bone Neoplasms; Carcinogens; Drug Evaluation; Humans; Indomethacin; Neoplasm Metas

1979
The influence of platelet aggregation inhibitors on metastasis formation in mice (3LL).
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, Aug-30, Volume: 86, Issue:3

    Topics: Animals; Aspirin; Bencyclane; Cyproheptadine; Dipyridamole; Female; Lung Neoplasms; Male; Mice; Mice

1976
Initial tumor cell arrest in animals of defined coagulative status.
    International journal of cancer, 1978, Jun-15, Volume: 21, Issue:6

    Topics: Animals; Anticoagulants; Aspirin; Blood Coagulation; Carcinoma; Heparin; Lymphoma, Non-Hodgkin; Mice

1978
Enhancement of natural and antibody-dependent lymphocyte cytotoxicity by drugs which inhibit prostaglandin production by tumor target cells.
    Cellular immunology, 1978, Volume: 39, Issue:1

    Topics: Antibody-Dependent Cell Cytotoxicity; Aspirin; Cell Line; Cytotoxicity, Immunologic; Dose-Response R

1978
Tumor-mediated immunosuppression: prevention by inhibitors of prostaglandin synthesis.
    Prostaglandins, 1977, Volume: 14, Issue:6

    Topics: Animals; Antibody Formation; Aspirin; Cell Line; Erythrocytes; Flufenamic Acid; Immunosuppression Th

1977
Investigations on prostatic adenocarcinomas in rats.
    Oncology, 1977, Volume: 34, Issue:3

    Topics: Adenocarcinoma; Anesthetics; Animals; Aspirin; Cell Line; Female; Immunotherapy; Indomethacin; Lung

1977
Effect of hemostasis modifiers of the activity of VP 16 213 on Lewis lung carcinoma.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1977, Volume: 27, Issue:5

    Topics: Animals; Aspirin; Etoposide; Hemostasis; Heparin; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm

1977
Alteration of tumor growth by aspirin and indomethacin: studies with two transplantable tumors in mouse.
    European journal of pharmacology, 1976, Volume: 37, Issue:2

    Topics: Animals; Aspirin; Body Weight; Cell Count; Histamine; Histidine Decarboxylase; Indomethacin; Mice; M

1976
Indomethacin induces the suppression of plasma neutral proteinase activity in mice: possible relationship to efficacy as an anti-inflammatory drug and induction of alterations in the immune system.
    Journal of clinical & laboratory immunology, 1986, Volume: 20, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chlorides; Dose-Response Relationship, Dr

1986
Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Humans; Immunologic Techniques; Lung Neop

1988
Haematological effects of aspirin.
    Lancet (London, England), 1972, Sep-30, Volume: 2, Issue:7779

    Topics: Adenocarcinoma; Animals; Aspirin; Heparin; Lung Neoplasms; Mice; Neoplasm Metastasis; Neoplasms, Exp

1972
Anti-metastatic effect of aspirin.
    Lancet (London, England), 1972, Oct-28, Volume: 2, Issue:7783

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Aspirin; Fibrosarcoma; Humans; Mice; Neoplasm Metast

1972
Aspirin and tumour metastasis.
    Lancet (London, England), 1972, Dec-30, Volume: 2, Issue:7792

    Topics: Animals; Aspirin; Blood Platelets; Lung Neoplasms; Neoplasm Metastasis; Neoplasms, Experimental; Rab

1972
Production of histamine-like and prostaglandin-like substances from serum incubated with rat, dog, mouse or human tumours.
    British journal of experimental pathology, 1973, Volume: 54, Issue:2

    Topics: Acetates; Animals; Aspirin; Carcinoma, Hepatocellular; Complement System Proteins; Dogs; Histamine;

1973