aspirin has been researched along with Experimental Mammary Neoplasms in 12 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Efficacy of PA-2 was evaluated in human breast cancer cells in vitro, and in orthotopic and subcutaneous TNBC xenografts in nude mice." | 5.40 | Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stress. ( Alston, N; Cheng, KW; Huang, L; Mackenzie, GG; Ouyang, N; Rigas, B; Sun, Y; Vrankova, K; Wong, CC, 2014) |
| "Efficacy of PA-2 was evaluated in human breast cancer cells in vitro, and in orthotopic and subcutaneous TNBC xenografts in nude mice." | 1.40 | Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stress. ( Alston, N; Cheng, KW; Huang, L; Mackenzie, GG; Ouyang, N; Rigas, B; Sun, Y; Vrankova, K; Wong, CC, 2014) |
| "Both the B16 melanoma and the MMTV carcinoma parental cell lines, which can be classed as intermediate metastatic, aggregated platelets well." | 1.27 | Tumour-cell-induced platelet aggregation: studies with cloned metastatic and non-metastatic variants. ( Crawford, N; Lampugnani, MG, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Santucci-Pereira, J | 1 |
| Pogash, TJ | 1 |
| Patel, A | 1 |
| Hundal, N | 1 |
| Barton, M | 1 |
| Camoirano, A | 1 |
| Micale, RT | 1 |
| La Maestra, S | 1 |
| Balansky, R | 1 |
| De Flora, S | 1 |
| Russo, J | 1 |
| Pan, W | 1 |
| Zhang, X | 1 |
| Gao, P | 1 |
| Li, N | 1 |
| Tang, B | 1 |
| Huang, L | 1 |
| Wong, CC | 1 |
| Mackenzie, GG | 1 |
| Sun, Y | 1 |
| Cheng, KW | 1 |
| Vrankova, K | 1 |
| Alston, N | 1 |
| Ouyang, N | 1 |
| Rigas, B | 1 |
| Girolami, F | 1 |
| Abbadessa, G | 1 |
| Racca, S | 1 |
| Spaccamiglio, A | 1 |
| Piccione, F | 1 |
| Dacasto, M | 1 |
| Carletti, M | 1 |
| Gardini, G | 1 |
| Di Carlo, F | 1 |
| Nebbia, C | 1 |
| Mei, ZR | 1 |
| Zheng, HL | 1 |
| Wu, HP | 1 |
| Zhu, XG | 1 |
| Rosenberg, L | 1 |
| Suzui, N | 2 |
| Sugie, S | 2 |
| Rahman, KM | 1 |
| Ohnishi, M | 1 |
| Yoshimi, N | 1 |
| Wakabayashi, K | 1 |
| Mori, H | 2 |
| Rahman, W | 1 |
| Sansom, OJ | 1 |
| Stark, LA | 1 |
| Dunlop, MG | 1 |
| Clarke, AR | 1 |
| Rao, GA | 1 |
| Abraham, S | 1 |
| Lampugnani, MG | 1 |
| Crawford, N | 1 |
| Gasic, GJ | 1 |
| Gasic, TB | 1 |
| Galanti, N | 1 |
| Johnson, T | 1 |
| Murphy, S | 1 |
12 other studies available for aspirin and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Aspirin abrogates impairment of mammary gland differentiation induced by early in life second-hand smoke in mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinogenesis; Cel | 2018 |
An anti-inflammatory nanoagent for tumor-targeted photothermal therapy.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; Cell | 2019 |
Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stress.
Topics: Acetylation; Animals; Aspirin; Breast Neoplasms; Cell Line, Tumor; ErbB Receptors; Female; Humans; M | 2014 |
Time-dependent acetylsalicylic acid effects on liver CYP1A and antioxidant enzymes in a rat model of 7,12-dimethylbenzanthracene (DMBA)-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Aspirin; Cytochrom | 2008 |
[Inhibitory effects of Aspisol on growth of transplanted breast cancer in C3H mice].
Topics: Animals; Apoptosis; Aspirin; Body Weight; Caspase 3; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Fe | 2006 |
Aspirin and breast cancer: no surprises yet.
Topics: Animals; Antineoplastic Agents; Aspirin; Breast Neoplasms; Drug Utilization; Female; Humans; Mammary | 1996 |
Inhibitory effects of diallyl disulfide or aspirin on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mammary carcinogenesis in rats.
Topics: Administration, Oral; Allyl Compounds; Animals; Anticarcinogenic Agents; Aspirin; Carcinogens; Corn | 1997 |
Chemoprevention of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine-induced mammary carcinogenesis in rats.
Topics: Allyl Compounds; Animals; Anticarcinogenic Agents; Aspirin; Benzoflavones; beta-Naphthoflavone; Carc | 1999 |
Suppression of intestinal and mammary neoplasia by lifetime administration of aspirin in Apc(Min/+) and Apc(Min/+), Msh2(-/-) mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Base Pair Mismatch; Colorectal Neoplasms, | 2001 |
Reduced growth rate of transplantable mammary adenocarcinoma in C3H mice fed eicosa-5,8,11,14-tetraynoic acid.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenocarcinoma; Animals; Arachidonic Acids; Aspirin; Dietary Fats; | 1977 |
Tumour-cell-induced platelet aggregation: studies with cloned metastatic and non-metastatic variants.
Topics: Adenosine Diphosphate; Animals; Aspirin; Cell Line; Creatine Kinase; Heparin; Humans; Mammary Neopla | 1987 |
Platelet-tumor-cell interactions in mice. The role of platelets in the spread of malignant disease.
Topics: Adenocarcinoma; Animals; Aspirin; Blood Cell Count; Blood Platelets; Carcinoma; Cell Survival; Chrom | 1973 |