aspirin has been researched along with Esophagitis, Peptic in 16 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Esophagitis, Peptic: INFLAMMATION of the ESOPHAGUS that is caused by the reflux of GASTRIC JUICE with contents of the STOMACH and DUODENUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Male gender, smoking, alcohol drinking, consumption of coffee, large waist circumference, infrequent medication of antacids, aspirin and NSAIDs, infrequent and mild GERD symptoms were all significantly associated with ED on univariate analysis." | 3.77 | [Clinical characteristics of gastroesophageal reflux disease with esophageal injury in korean: focusing on risk factors]. ( Cho, KB; Jang, BI; Jeon, SW; Jung, JT; Jung, MK; Kim, ES; Kim, EY; Kim, KO; Kim, SK; Kwon, JG; Lee, JH; Lee, SH; Lee, SJ; Park, CK; Park, KS; Seo, HE; Yang, CH, 2011) |
| "05) correlation was found in the following associations: aspirin and multiple gastric ulcers, aspirin and severe erosive gastritis; non-steroidal antiinflammatory drugs and multiple duodenal ulcers, non-steroidal antiinflammatory drugs and mild erosive gastritis." | 3.67 | [Peptic lesions of the upper digestive tract and drugs. Prospective study]. ( Borel, GA; de Peyer, R; Gaillard, C; Loizeau, E, 1984) |
| " Fifteen healthy Japanese volunteers are dosed for 7 days in a 5-way randomly crossover trial: placebo, aspirin 100 mg, rabeprazole 10 mg, and aspirin 100 mg plus rabeprazole 10 mg either once daily or 4 times per day." | 2.75 | Esophageal mucosal injury with low-dose aspirin and its prevention by rabeprazole. ( Furuta, T; Hishida, A; Ikuma, M; Kodaira, C; Nishino, M; Sugimoto, M; Sugimura, H; Tanaka, T; Yamade, M, 2010) |
| "Reflux esophagitis was induced in anesthetized rats by ligating the pylorus and limiting ridge transitional region between the forestomach and the corpus of stomach." | 1.37 | Nitric oxide (NO)-releasing aspirin exhibits a potent esophagoprotection in experimental model of acute reflux esophagitis. Role of nitric oxide and proinflammatory cytokines. ( Brzozowski, T; Konturek, SJ; Kwiecien, S; Mazurkiewicz-Janik, M; Pajdo, R; Pawlik, M; Pawlik, WW; Ptak-Belowska, A; Sliwowski, Z, 2011) |
| "The incidence of esophageal and gastric cancers was high at 5." | 1.36 | Impact of upper gastrointestinal lesions in patients on low-dose aspirin therapy: preliminary study. ( Kawai, T; Watanabe, M; Yamashina, A, 2010) |
| "In total, 230 reflux esophagitis, 224 Barrett's esophagus, and 227 esophageal adenocarcinoma and 260 population controls were recruited." | 1.33 | Nonsteroidal anti-inflammatory drugs and the esophageal inflammation-metaplasia-adenocarcinoma sequence. ( Anderson, LA; Comber, H; Ferguson, HR; Johnston, BT; McGuigan, J; Murphy, SJ; Murray, LJ; Reynolds, JV; Watson, RG, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Masuda, T | 1 |
| Yano, F | 1 |
| Omura, N | 1 |
| Tsuboi, K | 1 |
| Hoshino, M | 1 |
| Yamamoto, SR | 1 |
| Akimoto, S | 1 |
| Kashiwagi, H | 1 |
| Yanaga, K | 1 |
| Sugimoto, M | 1 |
| Nishino, M | 1 |
| Kodaira, C | 1 |
| Yamade, M | 1 |
| Ikuma, M | 1 |
| Tanaka, T | 1 |
| Sugimura, H | 1 |
| Hishida, A | 1 |
| Furuta, T | 1 |
| Kawai, T | 1 |
| Watanabe, M | 1 |
| Yamashina, A | 1 |
| Pawlik, M | 1 |
| Pajdo, R | 1 |
| Kwiecien, S | 1 |
| Ptak-Belowska, A | 1 |
| Sliwowski, Z | 1 |
| Mazurkiewicz-Janik, M | 1 |
| Konturek, SJ | 1 |
| Pawlik, WW | 1 |
| Brzozowski, T | 1 |
| Lee, SJ | 1 |
| Jung, MK | 1 |
| Kim, SK | 1 |
| Jang, BI | 1 |
| Lee, SH | 1 |
| Kim, KO | 1 |
| Kim, ES | 1 |
| Cho, KB | 1 |
| Park, KS | 1 |
| Kim, EY | 1 |
| Jung, JT | 1 |
| Kwon, JG | 1 |
| Lee, JH | 1 |
| Yang, CH | 1 |
| Park, CK | 1 |
| Seo, HE | 1 |
| Jeon, SW | 1 |
| Füessl, HS | 1 |
| Vogt, W | 1 |
| Anderson, LA | 1 |
| Johnston, BT | 1 |
| Watson, RG | 1 |
| Murphy, SJ | 1 |
| Ferguson, HR | 1 |
| Comber, H | 1 |
| McGuigan, J | 1 |
| Reynolds, JV | 1 |
| Murray, LJ | 1 |
| Stiefelhagen, P | 1 |
| Gaillard, C | 1 |
| Borel, GA | 1 |
| de Peyer, R | 1 |
| Loizeau, E | 1 |
| Avidan, B | 1 |
| Sonnenberg, A | 1 |
| Schnell, TG | 1 |
| Sontag, SJ | 1 |
| Smith, VM | 1 |
| Liebman, WM | 1 |
| Holvoet, J | 1 |
| Terriere, L | 1 |
| Van Hee, W | 1 |
| Verbist, L | 1 |
| Fierens, E | 1 |
| Hautekeete, ML | 1 |
| Berman, PM | 1 |
| Kirsner, JB | 1 |
| Stafford, ES | 1 |
| Zuidema, GD | 1 |
| Cameron, JL | 1 |
1 review available for aspirin and Esophagitis, Peptic
| Article | Year |
|---|---|
[Gastroenterology in the elderly].
Topics: Abdominal Pain; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, N | 2005 |
2 trials available for aspirin and Esophagitis, Peptic
| Article | Year |
|---|---|
Esophageal mucosal injury with low-dose aspirin and its prevention by rabeprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Anti-Inflammatory Agents, Non-Steroid | 2010 |
Relation of upper gastrointestinal bleeding to non-steroidal anti-inflammatory drugs and aspirin: a case-control study.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control | 1991 |
13 other studies available for aspirin and Esophagitis, Peptic
| Article | Year |
|---|---|
Effect of Low-Dose Aspirin on Chronic Acid Reflux Esophagitis in Rats.
Topics: Administration, Oral; Animals; Aspirin; Body Weight; Chronic Disease; Dose-Response Relationship, Dr | 2018 |
Impact of upper gastrointestinal lesions in patients on low-dose aspirin therapy: preliminary study.
Topics: Aged; Aspirin; Cardiovascular Agents; Duodenal Ulcer; Endoscopy, Digestive System; Esophageal Neopla | 2010 |
Nitric oxide (NO)-releasing aspirin exhibits a potent esophagoprotection in experimental model of acute reflux esophagitis. Role of nitric oxide and proinflammatory cytokines.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 1; Cyclooxygena | 2011 |
[Clinical characteristics of gastroesophageal reflux disease with esophageal injury in korean: focusing on risk factors].
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Aspiri | 2011 |
[Heartburn without esophagitis. Symptoms more important than the finding?].
Topics: Androstadienes; Antacids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ul | 2003 |
Nonsteroidal anti-inflammatory drugs and the esophageal inflammation-metaplasia-adenocarcinoma sequence.
Topics: Acetaminophen; Adenocarcinoma; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Asp | 2006 |
[Gastroenterology in family practice. Updates for your "stomach patient"].
Topics: Anti-Ulcer Agents; Aspirin; Clopidogrel; Dyspepsia; Esophagitis, Peptic; Family Practice; Heartburn; | 2006 |
[Peptic lesions of the upper digestive tract and drugs. Prospective study].
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Esophagitis, Peptic; Ethanol; Female; Gastritis; Humans; M | 1984 |
Risk factors for erosive reflux esophagitis: a case-control study.
Topics: Adult; Age Distribution; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; C | 2001 |
Association of aspirin ingestion with symptomatic esophageal hiatus hernia.
Topics: Aspirin; Barium Sulfate; Esophagitis, Peptic; Esophagogastric Junction; Esophagus; Gastroesophageal | 1978 |
Diagnosis and management of upper gastrointestinal hemorrhage in children.
Topics: Aspirin; Blood Transfusion; Child; Child, Preschool; Esophageal and Gastric Varices; Esophagitis, Pe | 1976 |
Recognizing and avoiding adverse gastrointestinal effects of drugs.
Topics: Aged; Antacids; Aspirin; Colon; Digestive System; Drug Antagonism; Drug Interactions; Drug-Related S | 1974 |
Unusual causes of occult bleeding from the gastrointestinal tract.
Topics: Adolescent; Adult; Aged; Anemia; Aspirin; Child; Diagnosis, Differential; Esophagitis, Peptic; Femal | 1970 |