Page last updated: 2024-10-23

aspirin and Esophageal and Gastric Varices

aspirin has been researched along with Esophageal and Gastric Varices in 29 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Esophageal and Gastric Varices: Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).

Research Excerpts

ExcerptRelevanceReference
"This retrospective multicenter study provides first data indicating a beneficial effect of aspirin on transplant-free survival after TIPS implantation in patients with refractory ascites."8.12Aspirin improves transplant-free survival after TIPS implantation in patients with refractory ascites: a retrospective multicentre cohort study. ( Bettinger, D; Gu, W; Heinzow, H; Huber, JP; Jansen, C; Köhler, M; Maschmeier, M; Masthoff, M; Meyer, C; Praktiknjo, M; Schindler, P; Schmidt, HH; Schoster, M; Schultheiss, M; Seifert, LL; Seifert, QE; Sturm, L; Trebicka, J; Weller, JF; Wildgruber, M; Wilms, C, 2022)
"This retrospective multicenter study provides first data indicating a beneficial effect of aspirin on transplant-free survival after TIPS implantation in patients with refractory ascites."4.12Aspirin improves transplant-free survival after TIPS implantation in patients with refractory ascites: a retrospective multicentre cohort study. ( Bettinger, D; Gu, W; Heinzow, H; Huber, JP; Jansen, C; Köhler, M; Maschmeier, M; Masthoff, M; Meyer, C; Praktiknjo, M; Schindler, P; Schmidt, HH; Schoster, M; Schultheiss, M; Seifert, LL; Seifert, QE; Sturm, L; Trebicka, J; Weller, JF; Wildgruber, M; Wilms, C, 2022)
"96) as well as history of hematemesis, melena in the past 30 days, positive nasogastric aspirate, prior upper gastrointestinal bleeding or use of aspirin or non-steroidal anti-inflammatory."3.83Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics. ( Camus, M; Dulai, GS; Ghassemi, KA; Jensen, DM; Jutabha, R; Khungar, V; Kovacs, TO; Machicado, GA; Ohning, GV, 2016)
"The aim of this case-control study was to assess the risk of bleeding from esophageal varices associated with aspirin and non-steroidal anti-inflammatory drug consumption."3.69Non-steroidal anti-inflammatory drugs and variceal bleeding: a case-control study. ( Barrioz, T; Beauchant, M; de Lédinghen, V; Foucher, J; Ingrand, P; Mannant, PR; Perault, MC; Silvain, C; Vandel, B, 1996)
" Taking aspirin is exceptional before rupture of esophageal varices."3.65[Clinical aspects and course of drug-induced upper digestive hemorrhage]. ( Benarous, JJ; Frexinos, J; Legrand, G; Pascal, JP; Ribet, A; Suduca, P; Tournut, R, 1976)
"In addition, diverticular bleeding in the elderly was highly associated with intake of Aspirin."1.33[Epidemiology of gastrointestinal bleeding in the elderly]. ( Bertschinger, P; Bühler, H; Geyer, M; Stamenic, I, 2006)
"Acute bleeding from oesophageal varices is a major complication of cirrhosis of the liver."1.30Anti-inflammatory drugs and variceal bleeding: a case-control study. ( Beauchant, M; Becker, MC; Bernard, P; De Lédinghen, V; Fourdan, O; Gourlaouen, A; Heresbach, D; Ingrand, P; Liebaert-Bories, MP; Nousbaum, JB; Ribard, D; Silvain, C, 1999)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199015 (51.72)18.7374
1990's2 (6.90)18.2507
2000's5 (17.24)29.6817
2010's5 (17.24)24.3611
2020's2 (6.90)2.80

Authors

AuthorsStudies
Seifert, LL1
Schindler, P1
Sturm, L1
Gu, W1
Seifert, QE1
Weller, JF1
Jansen, C1
Praktiknjo, M1
Meyer, C1
Schoster, M1
Wilms, C1
Maschmeier, M1
Schmidt, HH1
Masthoff, M1
Köhler, M1
Schultheiss, M1
Huber, JP1
Bettinger, D1
Trebicka, J1
Wildgruber, M1
Heinzow, H1
Singh, J1
Wozniak, A1
Cotler, SJ1
Dhanarajan, A1
Aldrich, D1
Park, D1
Kasia, C1
Schmidt, B1
Scaglione, S1
Shaukat, A1
Waheed, S1
Alexander, E1
Washko, D1
Dawn, B1
Olyaee, M1
Gupta, K1
Kondo, T1
Maruyama, H1
Kiyono, S1
Sekimoto, T1
Shimada, T1
Takahashi, M1
Okugawa, H1
Kobayashi, S1
Yoshizumi, H1
Yokosuka, O1
Bruno, M1
Marengo, A1
Elia, C1
Caronna, S1
Debernardi-Venon, W1
Manfrè, SF1
Musso, A1
Puglisi, F1
Sguazzini, C1
Rizzetto, M1
De Angelis, C1
Camus, M1
Khungar, V1
Jensen, DM1
Ohning, GV1
Kovacs, TO1
Jutabha, R1
Ghassemi, KA1
Machicado, GA1
Dulai, GS1
Biggerstaff, BJ1
Jackson, D1
Chiu, PW1
Ng, EK1
Dworzynski, K1
Pollit, V1
Kelsey, A1
Higgins, B1
Palmer, K1
Di Fiore, F1
Lecleire, S1
Merle, V1
Hervé, S1
Duhamel, C1
Dupas, JL1
Vandewalle, A1
Bental, A1
Gouerou, H1
Le Page, M1
Amouretti, M1
Czernichow, P1
Lerebours, E1
Geyer, M1
Stamenic, I1
Bühler, H1
Bertschinger, P1
Katz, MG1
Shimonov, M1
Elias, S1
Ben Eli, M1
Hauptman, E1
Sasson, L1
Kooiman, AM1
Kootstra, G1
Zwierstra, RP1
de Lédinghen, V2
Mannant, PR1
Foucher, J1
Perault, MC1
Barrioz, T1
Ingrand, P2
Vandel, B1
Silvain, C2
Beauchant, M2
Heresbach, D1
Fourdan, O1
Bernard, P1
Liebaert-Bories, MP1
Nousbaum, JB1
Gourlaouen, A1
Becker, MC1
Ribard, D1
Franco, D1
Durandy, Y1
Deporte, A1
Bismuth, H1
Tournut, R1
Pascal, JP1
Frexinos, J1
Suduca, P1
Legrand, G1
Benarous, JJ1
Ribet, A1
Graham, DY1
Davis, RE1
Liebman, WM1
Conte, M1
Jarrousse, P1
Hegarty, MM1
Grime, RT1
Schofield, PF1
Lightdale, CJ1
Kurtz, RC1
Boyle, CC1
Sherlock, P1
Winawer, SJ1
Lataste, J1
Le Picard, P1
Welch, CE1
Hedberg, S1
Kelner, S1
Ferraz, E1
Wanderley, F1
Benhamou, JP1
Debray, C1
Hamburger, J1
Loygue, J1
Roux, M1
Pequignot, H1
Preston, FW1
Cummins, GM1
Needham, CD1
Kyle, J1
Jones, PF1
Johnston, SJ1
Kerridge, DF1
Ferguson, CC1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sclerotherapy With Polidocanol Foam in the Treatment of First, Second and Third-Grade Hemorrhoidal Disease in Patients With Liver Cirrhosis: A Prospective, Cohort Trial[NCT05807425]Phase 2/Phase 340 participants (Anticipated)Interventional2023-03-31Recruiting
Video Capsule Endoscopy for Lesion Localization and Diagnosis in Patients With Severe Hematochezia[NCT03616041]50 participants (Anticipated)Observational2021-02-10Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for aspirin and Esophageal and Gastric Varices

ArticleYear
Predicting poor outcome from acute upper gastrointestinal hemorrhage.
    Gastroenterology clinics of North America, 2009, Volume: 38, Issue:2

    Topics: Aging; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Endoscopy, Gastrointestinal; Esophageal and

2009
Gastrointestinal hemorrhage. I. General considerations of diagnosis and the rapy.
    Advances in surgery, 1973, Volume: 7

    Topics: Anus Diseases; Aspirin; Biliary Tract Diseases; Blood Coagulation Disorders; Burns; Child; Child, Pr

1973

Other Studies

27 other studies available for aspirin and Esophageal and Gastric Varices

ArticleYear
Aspirin improves transplant-free survival after TIPS implantation in patients with refractory ascites: a retrospective multicentre cohort study.
    Hepatology international, 2022, Volume: 16, Issue:3

    Topics: Ascites; Aspirin; Cohort Studies; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Human

2022
Combined Use of Aspirin and Statin is Associated With a Decreased Incidence of Hepatocellular Carcinoma.
    Journal of clinical gastroenterology, 2022, 04-01, Volume: 56, Issue:4

    Topics: Aspirin; Carcinoma, Hepatocellular; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hum

2022
Etiology of gastrointestinal bleeding in patients on dual antiplatelet therapy.
    Journal of digestive diseases, 2018, Volume: 19, Issue:2

    Topics: Aged; Aspirin; Clopidogrel; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Esophageal and G

2018
Similarities and differences in the clinical features between cardia varices and esophageal varices.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardia; Esophageal

2014
Antiplatelet and anticoagulant drugs management before gastrointestinal endoscopy: do clinicians adhere to current guidelines?
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2015, Volume: 47, Issue:1

    Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Biopsy; Cohort Studies; Colonic Polyps; Colonoscop

2015
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:9

    Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont

2016
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:9

    Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont

2016
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:9

    Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont

2016
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:9

    Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont

2016
The exact distribution of Cochran's heterogeneity statistic in one-way random effects meta-analysis.
    Statistics in medicine, 2008, Dec-20, Volume: 27, Issue:29

    Topics: Aspirin; Biometry; Confidence Intervals; Diuretics; Esophageal and Gastric Varices; Female; Glycerol

2008
Management of acute upper gastrointestinal bleeding: summary of NICE guidance.
    BMJ (Clinical research ed.), 2012, Jun-13, Volume: 344

    Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspir

2012
Changes in characteristics and outcome of acute upper gastrointestinal haemorrhage: a comparison of epidemiology and practices between 1996 and 2000 in a multicentre French study.
    European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; A

2005
[Epidemiology of gastrointestinal bleeding in the elderly].
    Praxis, 2006, May-10, Volume: 95, Issue:19

    Topics: Age Factors; Aged; Aged, 80 and over; Angiodysplasia; Anti-Inflammatory Agents, Non-Steroidal; Aspir

2006
Portal vein thrombosis associated with coronary artery bypass surgery.
    The Journal of cardiovascular surgery, 2008, Volume: 49, Issue:1

    Topics: Aged; Aspirin; Bacteremia; Clopidogrel; Coagulase; Coronary Artery Bypass; Esophageal and Gastric Va

2008
Portal hypertension in children due to thrombosis of the portal vein.
    The Netherlands journal of surgery, 1982, Volume: 34, Issue:3

    Topics: Adolescent; Aspirin; Catheterization; Child; Child, Preschool; Esophageal and Gastric Varices; Femal

1982
Non-steroidal anti-inflammatory drugs and variceal bleeding: a case-control study.
    Journal of hepatology, 1996, Volume: 24, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studi

1996
Anti-inflammatory drugs and variceal bleeding: a case-control study.
    Gut, 1999, Volume: 44, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Esophageal and

1999
Upper gastrointestinal haemorrhage in hepatic cirrhosis: causes and relation to hepatic failure and stress.
    Lancet (London, England), 1977, Jan-29, Volume: 1, Issue:8005

    Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aspirin; Chronic Disease; Esophagea

1977
[Clinical aspects and course of drug-induced upper digestive hemorrhage].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1976, Nov-23, Volume: 52, Issue:40

    Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoag

1976
Acute upper-gastrointestinal hemorrhage. New observations on an old problem.
    The American journal of digestive diseases, 1978, Volume: 23, Issue:1

    Topics: Alcohol Drinking; Aspirin; Duodenal Ulcer; Esophageal and Gastric Varices; Esophagoscopy; Gastritis;

1978
Diagnosis and management of upper gastrointestinal hemorrhage in children.
    Pediatric annals, 1976, Volume: 5, Issue:11

    Topics: Aspirin; Blood Transfusion; Child; Child, Preschool; Esophageal and Gastric Varices; Esophagitis, Pe

1976
[The fate of 165 hemorrhagic ulcers treated in a special intensive care unit].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1973, Feb-14, Volume: 49, Issue:8

    Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Emergencies; Esoph

1973
The management of upper gastro-intestinal tract haemorrhage.
    The British journal of surgery, 1973, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Aged; Aortic Aneurysm; Aspirin; Carcinoma; Duodenal Ulcer; Esophageal and Gastric

1973
Cancer and upper gastrointestinal tract hemorrhage. Benign causes of bleeding demonstrated by endoscopy.
    JAMA, 1973, Oct-08, Volume: 226, Issue:2

    Topics: Acute Disease; Adenocarcinoma; Aspirin; Chronic Disease; Endoscopy; Esophageal and Gastric Varices;

1973
[Upper digestive hemorrhages due to gastritis or of unknown cause. (Apropos of 140 cases)].
    Journal de chirurgie, 1973, Volume: 106, Issue:6

    Topics: Alcoholism; Aspirin; Endoscopy; Esophageal and Gastric Varices; Fiber Optic Technology; Gastrectomy;

1973
[Hematemesis: study on its causation by drugs containing acetylsalicylic acid in schistosomotic portal hypertension].
    Revista da Associacao Medica Brasileira, 1966, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Aspirin; Child; Child, Preschool; Esophageal and Gastric Varices; Female; H

1966
[Procedure to follow in case of severe hematemesis].
    La Presse medicale, 1969, Feb-22, Volume: 77, Issue:10

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aspirin; Blood Transfusion; Blood Volume Determin

1969
Problems in the management of massive hemorrhage from the esophagogastrointestinal tract.
    The Surgical clinics of North America, 1970, Volume: 50, Issue:1

    Topics: Aged; Angiography; Aspirin; Cineradiography; Diverticulum, Colon; Endoscopy; Esophageal and Gastric

1970
Aspirin and alcohol in gastrointestinal haemorrhage.
    Gut, 1971, Volume: 12, Issue:10

    Topics: Aspirin; Drug Synergism; Duodenal Ulcer; Esophageal and Gastric Varices; Ethanol; Female; Gastritis;

1971
Management of portal hypertension in children.
    Surgery, 1968, Volume: 63, Issue:6

    Topics: Aspirin; Child, Preschool; Esophageal and Gastric Varices; Hematemesis; Humans; Hypertension, Portal

1968