aspirin has been researched along with Esophageal Squamous Cell Carcinoma in 8 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Esophageal Squamous Cell Carcinoma: A carcinoma that originates usually from cells on the surface of the middle and lower third of the ESOPHAGUS. Tumor cells exhibit typical squamous morphology and form large polypoid lesions. Mutations in RNF6, LZTS1, TGFBR2, DEC1, and WWOX1 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To review the advances of studies on clinical results of aspirin's chemopreventive effect against esophageal squamous cell carcinoma (ESCC) and evidences for mechanisms of the antitumoural effects of aspirin in experimental research." | 8.90 | Aspirin and esophageal squamous cell carcinoma: bedside to bench. ( Cheng, R; Li, P; Zhang, S, 2014) |
| "To investigate the expression of ATPase family AAA domain-containing protein 2 (ATAD2) and kinesin family member 4A (KIF4A) in esophageal squamous cell carcinoma (ESCC) tissues and their association with clinicopathological features and to explore the role of ATAD2 in regulating KIF4A expression and biological functions in ESCC cells and the effect of aspirin on their expression." | 8.12 | Aspirin Exerts Its Antitumor Effect in Esophageal Squamous Cell Carcinoma by Downregulating the Expression of ATAD2 and KIF4A. ( Liu, C; Liu, H; Ren, Z; Wang, X; Zhang, M; Zhao, J; Zheng, Z, 2022) |
| "To review the advances of studies on clinical results of aspirin's chemopreventive effect against esophageal squamous cell carcinoma (ESCC) and evidences for mechanisms of the antitumoural effects of aspirin in experimental research." | 4.90 | Aspirin and esophageal squamous cell carcinoma: bedside to bench. ( Cheng, R; Li, P; Zhang, S, 2014) |
| "To investigate the expression of ATPase family AAA domain-containing protein 2 (ATAD2) and kinesin family member 4A (KIF4A) in esophageal squamous cell carcinoma (ESCC) tissues and their association with clinicopathological features and to explore the role of ATAD2 in regulating KIF4A expression and biological functions in ESCC cells and the effect of aspirin on their expression." | 4.12 | Aspirin Exerts Its Antitumor Effect in Esophageal Squamous Cell Carcinoma by Downregulating the Expression of ATAD2 and KIF4A. ( Liu, C; Liu, H; Ren, Z; Wang, X; Zhang, M; Zhao, J; Zheng, Z, 2022) |
| "An estimated 335 colorectal cancers, 22 oesophageal adenocarcinomas and 29 oesophageal squamous cell carcinomas (SCC) were potentially prevented due to daily aspirin use." | 3.81 | Cancers prevented in Australia in 2010 through the consumption of aspirin. ( Bain, CJ; Green, AC; Jordan, SJ; Kendall, BJ; Nagle, CM; Neale, RE; Whiteman, DC; Wilson, LF, 2015) |
| "The association of oesophageal cancer with drug use and clinical factors was evaluated." | 1.72 | Chemoprevention of Oesophageal Squamous-Cell Carcinoma and Adenocarcinoma: A Multicentre Retrospective Cohort Study. ( Arai, J; Arai, M; Hasatani, K; Hayakawa, Y; Honda, T; Ikeya, T; Kawahara, T; Kawai, T; Kiyotoki, S; Koike, K; Niikura, R; Nishida, T; Sumiyoshi, T; Suzuki, N; Tsuji, Y; Yamada, A; Yoshida, N, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 6 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arai, J | 1 |
| Niikura, R | 1 |
| Hayakawa, Y | 1 |
| Kawahara, T | 1 |
| Honda, T | 1 |
| Hasatani, K | 1 |
| Yoshida, N | 1 |
| Nishida, T | 1 |
| Sumiyoshi, T | 1 |
| Kiyotoki, S | 1 |
| Ikeya, T | 1 |
| Arai, M | 1 |
| Suzuki, N | 1 |
| Tsuji, Y | 1 |
| Yamada, A | 1 |
| Kawai, T | 1 |
| Koike, K | 1 |
| Jiang, J | 1 |
| Liu, J | 2 |
| Gao, P | 2 |
| Zhang, M | 1 |
| Ren, Z | 1 |
| Wang, X | 2 |
| Liu, C | 1 |
| Zheng, Z | 1 |
| Zhao, J | 1 |
| Liu, H | 1 |
| Song, Y | 1 |
| Zhong, X | 1 |
| Zhou, C | 1 |
| Shi, J | 1 |
| Wu, Z | 1 |
| Guo, Z | 1 |
| Wang, Z | 1 |
| Wu, Y | 1 |
| Xu, F | 1 |
| Zhang, L | 1 |
| Wang, T | 1 |
| Fu, X | 1 |
| Jin, T | 1 |
| Zhang, W | 1 |
| Ye, L | 1 |
| Zou, Z | 1 |
| Zheng, W | 1 |
| Fan, H | 1 |
| Deng, G | 1 |
| Lu, SH | 1 |
| Jiang, W | 1 |
| Yu, X | 1 |
| Li, P | 1 |
| Cheng, R | 1 |
| Zhang, S | 1 |
| Wilson, LF | 1 |
| Green, AC | 1 |
| Kendall, BJ | 1 |
| Jordan, SJ | 1 |
| Nagle, CM | 1 |
| Bain, CJ | 1 |
| Neale, RE | 1 |
| Whiteman, DC | 1 |
2 reviews available for aspirin and Esophageal Squamous Cell Carcinoma
| Article | Year |
|---|---|
Aspirin and Its Potential Preventive Role in Cancer: An Umbrella Review.
Topics: Aspirin; Chemoprevention; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Meta-Ana | 2020 |
Aspirin and esophageal squamous cell carcinoma: bedside to bench.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Squamous Cell; Esophageal Neoplasms; Es | 2014 |
6 other studies available for aspirin and Esophageal Squamous Cell Carcinoma
| Article | Year |
|---|---|
Chemoprevention of Oesophageal Squamous-Cell Carcinoma and Adenocarcinoma: A Multicentre Retrospective Cohort Study.
Topics: Adenocarcinoma; Aspirin; Case-Control Studies; Chemoprevention; Esophageal Neoplasms; Esophageal Squ | 2022 |
Effect of taking aspirin before diagnosis on the prognosis of esophageal squamous cell carcinoma and analysis of prognostic factors.
Topics: Aspirin; Carcinoma, Squamous Cell; Cyclooxygenase 2; Esophageal Neoplasms; Esophageal Squamous Cell | 2022 |
Aspirin Exerts Its Antitumor Effect in Esophageal Squamous Cell Carcinoma by Downregulating the Expression of ATAD2 and KIF4A.
Topics: Aspirin; ATPases Associated with Diverse Cellular Activities; Cell Line, Tumor; Cell Movement; Cell | 2022 |
The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt-PCAF pathway in promotion of esophageal squamous cell carcinoma growth.
Topics: Acetylation; Adaptor Proteins, Signal Transducing; Animals; Aspirin; Cell Line, Tumor; DNA; Esophage | 2020 |
Aspirin enhances the therapeutic efficacy of cisplatin in oesophageal squamous cell carcinoma by inhibition of putative cancer stem cells.
Topics: Animals; Aspirin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Dimethylnitrosamin | 2021 |
Cancers prevented in Australia in 2010 through the consumption of aspirin.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aspirin; Australia; Carcinoma, Squamous Cell; Colore | 2015 |