aspirin has been researched along with Erythema Nodosum in 15 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Erythema Nodosum: An erythematous eruption commonly associated with drug reactions or infection and characterized by inflammatory nodules that are usually tender, multiple, and bilateral. These nodules are located predominantly on the shins with less common occurrence on the thighs and forearms. They undergo characteristic color changes ending in temporary bruise-like areas. This condition usually subsides in 3-6 weeks without scarring or atrophy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six male patients of lepromatous leprosy with erythema nodosum leprosum reaction (ENL) reactions diagnosed clinically and by slit skin smear were treated with aspirin and clofazimine." | 7.83 | A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases. ( Sharma, PK; Singh, DK, 2016) |
| "A patient with chronic erythema nodosum of two years' duration, who did not respond to treatment with aspirin or with phenylbutazone therapy, had a dramatic response and improvement when treated with naproxen." | 7.66 | Control of chronic erythema nodosum with naproxen. ( Lehman, CW, 1980) |
| "Treatment with thalidomide provides an effective alternative to steroid therapy, gives better long-term control and avoids the adverse effects of prolonged steroid therapy." | 6.44 | The role of thalidomide in the management of erythema nodosum leprosum. ( Lockwood, DN; Walker, SL; Waters, MF, 2007) |
| "Six male patients of lepromatous leprosy with erythema nodosum leprosum reaction (ENL) reactions diagnosed clinically and by slit skin smear were treated with aspirin and clofazimine." | 3.83 | A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases. ( Sharma, PK; Singh, DK, 2016) |
| "A patient with chronic erythema nodosum of two years' duration, who did not respond to treatment with aspirin or with phenylbutazone therapy, had a dramatic response and improvement when treated with naproxen." | 3.66 | Control of chronic erythema nodosum with naproxen. ( Lehman, CW, 1980) |
| "Clofazimine treatment was superior to prednisolone (more treatment successes; RR 3." | 2.45 | Interventions for erythema nodosum leprosum. ( Lockwood, DN; Ramirez, J; Richardus, JH; van Brakel, WH; Van Veen, NH, 2009) |
| "Clofazimine treatment was superior to prednisolone (more treatment successes; RR 3." | 2.45 | Interventions for erythema nodosum leprosum. A Cochrane review. ( Lockwood, DN; Ramirez, J; Richardus, JH; Van Brakel, WH; Van Veen, NH, 2009) |
| "Treatment with thalidomide provides an effective alternative to steroid therapy, gives better long-term control and avoids the adverse effects of prolonged steroid therapy." | 2.44 | The role of thalidomide in the management of erythema nodosum leprosum. ( Lockwood, DN; Walker, SL; Waters, MF, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (53.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, PK | 1 |
| Singh, DK | 1 |
| Van Veen, NH | 2 |
| Lockwood, DN | 3 |
| van Brakel, WH | 2 |
| Ramirez, J | 2 |
| Richardus, JH | 2 |
| Zaki, SA | 1 |
| Shanbag, P | 1 |
| Kolyvanos, NU | 1 |
| Nigg, C | 1 |
| Käser, L | 1 |
| Vetter, W | 1 |
| Walker, SL | 1 |
| Waters, MF | 1 |
| Lehman, CW | 1 |
| Buckshee, K | 1 |
| Chadha, S | 1 |
| Förström, L | 1 |
| Winkelmann, RK | 1 |
| Blasetti, P | 1 |
| Kar, HK | 1 |
| Roy, RG | 1 |
| Cabanel, G | 1 |
| Jacquot, F | 1 |
| Phelip, X | 1 |
| Gras, JP | 1 |
| Mouries, D | 1 |
| Gol'dshteĭn, LM | 1 |
| Bakhtalovskiĭ, VB | 1 |
| Karat, AB | 1 |
| Thomas, G | 1 |
| Rao, PS | 1 |
| Reque, PG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study to Evaluate the Efficacy and Safety of Apremilast in Patients of Chronic and Recurrent Erythema Nodosum Leprosum[NCT04822909] | Phase 4 | 10 participants (Actual) | Interventional | 2019-09-15 | Completed | ||
| Methotrexate and Prednisolone Study in Erythema Nodosum Leprosum (MaPS in ENL[NCT03775460] | 550 participants (Anticipated) | Interventional | 2023-01-15 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for aspirin and Erythema Nodosum
| Article | Year |
|---|---|
Interventions for erythema nodosum leprosum.
Topics: Aspirin; Clofazimine; Erythema Nodosum; Humans; Leprostatic Agents; Leprosy, Lepromatous; Prednisolo | 2009 |
Interventions for erythema nodosum leprosum. A Cochrane review.
Topics: Aspirin; Clofazimine; Erythema Nodosum; Humans; Leprostatic Agents; Leprosy, Lepromatous; Prednisolo | 2009 |
The role of thalidomide in the management of erythema nodosum leprosum.
Topics: Aspirin; Controlled Clinical Trials as Topic; Decision Trees; Erythema Nodosum; Humans; Leprostatic | 2007 |
[Therapy of erythema nodosum].
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Erythema No | 1987 |
[Reaction of blast transformation of lymphocytes in dermato-venerology (review of the literature)].
Topics: Animals; Anti-Bacterial Agents; Antibodies; Aspirin; Dermatitis, Atopic; Eczema; Erythema Nodosum; F | 1974 |
2 trials available for aspirin and Erythema Nodosum
| Article | Year |
|---|---|
Comparison of colchicine and aspirin in the treatment of type 2 lepra reaction.
Topics: Adult; Aspirin; Clinical Trials as Topic; Colchicine; Double-Blind Method; Erythema Nodosum; Female; | 1988 |
Indomethacin in the management of erythema nodosum leprosum--a double-blind controlled trial.
Topics: Adolescent; Adult; Aspirin; Chloroquine; Clinical Trials as Topic; Erythema Nodosum; Humans; Indomet | 1969 |
8 other studies available for aspirin and Erythema Nodosum
| Article | Year |
|---|---|
A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clofazimine; Dapsone; Drug Therapy, Combina | 2016 |
Erythema nodosum as the presenting feature of rheumatic heart disease.
Topics: Aspirin; Child; Elbow; Erythema Nodosum; Humans; Knee; Male; Penicillin G Benzathine; Rheumatic Hear | 2011 |
[Erythema nodosum].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diagnosis, Differential; | 2007 |
Control of chronic erythema nodosum with naproxen.
Topics: Adult; Aspirin; Chronic Disease; Erythema Nodosum; Female; Humans; Naproxen; Phenylbutazone | 1980 |
Post tonsillitic erythema nodosum in pregnancy.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Erythema Nodosum; Female; Humans; Pregnancy | 1996 |
Granulomatous panniculitis in erythema nodosum.
Topics: Adult; Aged; Aspirin; Caseins; Erythema Induratum; Erythema Nodosum; Female; Follow-Up Studies; Gran | 1975 |
[Articular forms of sarcoidosis].
Topics: Adrenal Cortex Hormones; Adult; Ankylosis; Arthritis; Aspirin; Erythema Nodosum; Female; Humans; Lym | 1973 |
How I treat erythema nodosum.
Topics: Anti-Bacterial Agents; Aspirin; Erythema Nodosum; Female; Humans; Male; Medical History Taking | 1969 |