Page last updated: 2024-10-23

aspirin and Epithelial Ovarian Cancer

aspirin has been researched along with Epithelial Ovarian Cancer in 10 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Aspirin use was associated with a reduced risk of ovarian cancer (OR = 0."6.50Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium. ( Anton-Culver, H; Bandera, EV; Berchuck, A; Brinton, LA; Chandran, U; Cramer, DW; Doherty, JA; Gayther, SA; Gentry-Maharaj, A; Goode, EL; Goodman, MT; Hogdall, E; Jensen, A; Jordan, SJ; King, MG; Kjær, SK; Lo-Ciganic, WH; Lurie, G; Menon, U; Murphy, MA; Nagle, CM; Ness, RB; Olson, S; Pearce, CL; Pike, MC; Poole, EM; Ramus, SJ; Risch, HA; Rossing, MA; Schildkraut, JM; Terry, KL; Trabert, B; Vitonis, A; Webb, PM; Wentzensen, N; Wu, AH; Ziogas, A, 2014)
"We examined the association between postdiagnosis use of low-dose aspirin and mortality in a nationwide cohort of women with epithelial ovarian cancer between 2000 and 2012."3.88Aspirin use and ovarian cancer mortality in a Danish nationwide cohort study. ( Dehlendorff, C; Friis, S; Kjaer, SK; Verdoodt, F, 2018)
"Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% CIs for associations of aspirin, nonaspirin NSAIDs, and acetaminophen with risk of epithelial ovarian cancer."3.88Association of Analgesic Use With Risk of Ovarian Cancer in the Nurses' Health Studies. ( Barnard, ME; Curhan, GC; Eliassen, AH; Poole, EM; Rosner, BA; Terry, KL; Tworoger, SS, 2018)
"Aspirin use was associated with a reduced risk of ovarian cancer (OR = 0."2.50Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium. ( Anton-Culver, H; Bandera, EV; Berchuck, A; Brinton, LA; Chandran, U; Cramer, DW; Doherty, JA; Gayther, SA; Gentry-Maharaj, A; Goode, EL; Goodman, MT; Hogdall, E; Jensen, A; Jordan, SJ; King, MG; Kjær, SK; Lo-Ciganic, WH; Lurie, G; Menon, U; Murphy, MA; Nagle, CM; Ness, RB; Olson, S; Pearce, CL; Pike, MC; Poole, EM; Ramus, SJ; Risch, HA; Rossing, MA; Schildkraut, JM; Terry, KL; Trabert, B; Vitonis, A; Webb, PM; Wentzensen, N; Wu, AH; Ziogas, A, 2014)
"The findings of this study suggest that genetic susceptibility to ovarian cancer based on currently identified common genetic variants does not appear to modify the protective association between frequent aspirin use and ovarian cancer risk."1.91Association of Frequent Aspirin Use With Ovarian Cancer Risk According to Genetic Susceptibility. ( Anton-Culver, H; Berchuck, A; Doherty, JA; Goodman, MT; Harris, HR; Hurwitz, LM; Jordan, SJ; Menon, U; Modugno, F; Moysich, KB; Pearce, CL; Pharoah, PDP; Ramus, SJ; Schildkraut, JM; Shvetsov, YB; Trabert, B; Tworoger, SS; Webb, PM; Wentzensen, N; Wu, AH; Ziogas, A, 2023)
"The cases were all women in Denmark with epithelial ovarian cancer diagnosed during 2000-2009 (Paper 1) and 2000-2011 (Papers 2 and 3), identified in the Cancer Registry."1.42Drugs with potential chemopreventive properties in relation to epithelial ovarian cancer--a nationwide case-control study. ( Baandrup, L, 2015)
"Aspirin use was associated with a marginally significant reduction in incidence of VTEs within 2 years of diagnosis, HR 0."1.40Statins, aspirin and risk of thromboembolic events in ovarian cancer patients. ( Lavie, O; Leviov, M; Rennert, G; Rennert, HS; Sagi, S; Shai, A, 2014)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (80.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Sinha, BK1
Tokar, EJ1
Bortner, CD1
Hurwitz, LM1
Webb, PM2
Jordan, SJ2
Doherty, JA2
Harris, HR1
Goodman, MT2
Shvetsov, YB1
Modugno, F1
Moysich, KB1
Schildkraut, JM2
Berchuck, A2
Anton-Culver, H2
Ziogas, A2
Menon, U2
Ramus, SJ2
Wu, AH2
Pearce, CL2
Wentzensen, N2
Tworoger, SS3
Pharoah, PDP1
Trabert, B2
Verdoodt, F1
Kjaer, SK1
Dehlendorff, C1
Friis, S1
Merritt, MA1
Rice, MS1
Barnard, ME2
Hankinson, SE1
Matulonis, UA1
Poole, EM3
Curhan, GC1
Eliassen, AH1
Rosner, BA1
Terry, KL2
Tsoref, D1
Panzarella, T1
Oza, A1
Ness, RB1
Lo-Ciganic, WH1
Murphy, MA1
Goode, EL1
Brinton, LA1
Nagle, CM1
Risch, HA1
Rossing, MA1
Lurie, G1
Kjær, SK1
Hogdall, E1
Jensen, A1
Cramer, DW1
Vitonis, A1
Bandera, EV1
Olson, S1
King, MG1
Chandran, U1
Gayther, SA1
Gentry-Maharaj, A1
Pike, MC1
Shai, A1
Rennert, HS1
Rennert, G1
Sagi, S1
Leviov, M1
Lavie, O1
Baandrup, L1
Chiyoda, T1
Hart, PC1
Eckert, MA1
McGregor, SM1
Lastra, RR1
Hamamoto, R1
Nakamura, Y1
Yamada, SD1
Olopade, OI1
Lengyel, E1
Romero, IL1

Reviews

1 review available for aspirin and Epithelial Ovarian Cancer

ArticleYear
Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium.
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Australia;

2014

Other Studies

9 other studies available for aspirin and Epithelial Ovarian Cancer

ArticleYear
Molecular Mechanisms of Cytotoxicity of NCX4040, the Non-Steroidal Anti-Inflammatory NO-Donor, in Human Ovarian Cancer Cells.
    International journal of molecular sciences, 2022, Aug-03, Volume: 23, Issue:15

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, Ovarian Epitheli

2022
Association of Frequent Aspirin Use With Ovarian Cancer Risk According to Genetic Susceptibility.
    JAMA network open, 2023, 02-01, Volume: 6, Issue:2

    Topics: Aged; Aspirin; Carcinoma, Ovarian Epithelial; Female; Genetic Predisposition to Disease; Humans; Log

2023
Aspirin use and ovarian cancer mortality in a Danish nationwide cohort study.
    British journal of cancer, 2018, 02-20, Volume: 118, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Carcinoma, Ovarian Epithelial; Cohort Studies; Denmark; Fem

2018
Pre-diagnosis and post-diagnosis use of common analgesics and ovarian cancer prognosis (NHS/NHSII): a cohort study.
    The Lancet. Oncology, 2018, Volume: 19, Issue:8

    Topics: Acetaminophen; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma,

2018
Association of Analgesic Use With Risk of Ovarian Cancer in the Nurses' Health Studies.
    JAMA oncology, 2018, 12-01, Volume: 4, Issue:12

    Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Ovarian Epithelial;

2018
Aspirin in prevention of ovarian cancer: are we at the tipping point?
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Carcinoma,

2014
Statins, aspirin and risk of thromboembolic events in ovarian cancer patients.
    Gynecologic oncology, 2014, Volume: 133, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Carcinoma, Ovarian Epithelial;

2014
Drugs with potential chemopreventive properties in relation to epithelial ovarian cancer--a nationwide case-control study.
    Danish medical journal, 2015, Volume: 62, Issue:7

    Topics: Academic Dissertations as Topic; Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narc

2015
Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.
    Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:4

    Topics: Aspirin; BRCA1 Protein; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Chemoprevention; Cyclooxyge

2017