Page last updated: 2024-10-23

aspirin and Epithelial Neoplasms

aspirin has been researched along with Epithelial Neoplasms in 11 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Aspirin use was associated with a reduced risk of ovarian cancer (OR = 0."6.50Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium. ( Anton-Culver, H; Bandera, EV; Berchuck, A; Brinton, LA; Chandran, U; Cramer, DW; Doherty, JA; Gayther, SA; Gentry-Maharaj, A; Goode, EL; Goodman, MT; Hogdall, E; Jensen, A; Jordan, SJ; King, MG; Kjær, SK; Lo-Ciganic, WH; Lurie, G; Menon, U; Murphy, MA; Nagle, CM; Ness, RB; Olson, S; Pearce, CL; Pike, MC; Poole, EM; Ramus, SJ; Risch, HA; Rossing, MA; Schildkraut, JM; Terry, KL; Trabert, B; Vitonis, A; Webb, PM; Wentzensen, N; Wu, AH; Ziogas, A, 2014)
"Aspirin use was associated with a reduced risk of ovarian cancer (OR = 0."2.50Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium. ( Anton-Culver, H; Bandera, EV; Berchuck, A; Brinton, LA; Chandran, U; Cramer, DW; Doherty, JA; Gayther, SA; Gentry-Maharaj, A; Goode, EL; Goodman, MT; Hogdall, E; Jensen, A; Jordan, SJ; King, MG; Kjær, SK; Lo-Ciganic, WH; Lurie, G; Menon, U; Murphy, MA; Nagle, CM; Ness, RB; Olson, S; Pearce, CL; Pike, MC; Poole, EM; Ramus, SJ; Risch, HA; Rossing, MA; Schildkraut, JM; Terry, KL; Trabert, B; Vitonis, A; Webb, PM; Wentzensen, N; Wu, AH; Ziogas, A, 2014)
"The cases were all women in Denmark with epithelial ovarian cancer diagnosed during 2000-2009 (Paper 1) and 2000-2011 (Papers 2 and 3), identified in the Cancer Registry."1.42Drugs with potential chemopreventive properties in relation to epithelial ovarian cancer--a nationwide case-control study. ( Baandrup, L, 2015)
"Aspirin use was associated with a marginally significant reduction in incidence of VTEs within 2 years of diagnosis, HR 0."1.40Statins, aspirin and risk of thromboembolic events in ovarian cancer patients. ( Lavie, O; Leviov, M; Rennert, G; Rennert, HS; Sagi, S; Shai, A, 2014)
"Analgesic use may reduce ovarian cancer risk, possibly through antiinflammatory or antigonadotropic effects."1.35Analgesic drug use and risk of epithelial ovarian cancer. ( Cushing-Haugen, KL; Hannibal, CG; Rossing, MA; Wicklund, KG, 2008)
"Variant CYP2C9 genotypes enhanced the protective effect of ibuprofen on the prevention of colorectal cancer, and a dose-response relationship with respect to increasing numbers of variant alleles was seen (P interaction = ."1.33Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention. ( Andersen, K; Curtin, K; Levin, TR; Ma, KN; Samowitz, WS; Slattery, ML; Sweeney, C; Wolff, RK, 2006)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's7 (63.64)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Watari, J1
Tomita, T1
Tozawa, K1
Oshima, T1
Fukui, H1
Miwa, H1
Oliveira, VC1
Constante, SAR1
Polloni, L1
Orsolin, PC1
Silva-Oliveira, RG1
Machado, NM1
de Oliveira-Júnior, RJ1
Nepomuceno, JC1
Tsoref, D1
Panzarella, T1
Oza, A1
Trabert, B1
Ness, RB1
Lo-Ciganic, WH1
Murphy, MA1
Goode, EL1
Poole, EM1
Brinton, LA1
Webb, PM1
Nagle, CM1
Jordan, SJ1
Risch, HA1
Rossing, MA2
Doherty, JA1
Goodman, MT1
Lurie, G1
Kjær, SK1
Hogdall, E1
Jensen, A1
Cramer, DW1
Terry, KL1
Vitonis, A1
Bandera, EV1
Olson, S1
King, MG1
Chandran, U1
Anton-Culver, H1
Ziogas, A1
Menon, U1
Gayther, SA1
Ramus, SJ1
Gentry-Maharaj, A1
Wu, AH1
Pearce, CL1
Pike, MC1
Berchuck, A1
Schildkraut, JM1
Wentzensen, N1
Errico, A1
Shai, A1
Rennert, HS1
Rennert, G1
Sagi, S1
Leviov, M1
Lavie, O1
Baandrup, L1
Chiyoda, T1
Hart, PC1
Eckert, MA1
McGregor, SM1
Lastra, RR1
Hamamoto, R1
Nakamura, Y1
Yamada, SD1
Olopade, OI1
Lengyel, E1
Romero, IL1
Samowitz, WS1
Wolff, RK1
Curtin, K1
Sweeney, C1
Ma, KN1
Andersen, K1
Levin, TR1
Slattery, ML1
Hannibal, CG1
Wicklund, KG1
Cushing-Haugen, KL1
Lornoy, W1
Becaus, I1
Billiouw, JM1
Sierens, L1

Reviews

2 reviews available for aspirin and Epithelial Neoplasms

ArticleYear
Preventing Metachronous Gastric Cancer after the Endoscopic Resection of Gastric Epithelial Neoplasia: Roles of
    Gut and liver, 2020, 05-15, Volume: 14, Issue:3

    Topics: Aspirin; Endoscopic Mucosal Resection; Female; Gastric Mucosa; Gastritis, Atrophic; Helicobacter Inf

2020
Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium.
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Australia;

2014

Other Studies

9 other studies available for aspirin and Epithelial Neoplasms

ArticleYear
Protective effect of aspirin against mitomycin C-induced carcinogenicity, assessed by the test for detection of epithelial tumor clones (warts) in Drosophila melanogaster.
    Drug and chemical toxicology, 2018, Volume: 41, Issue:3

    Topics: Animals; Antioxidants; Apoptosis; Aspirin; Drosophila melanogaster; HeLa Cells; Humans; Mitomycin; N

2018
Aspirin in prevention of ovarian cancer: are we at the tipping point?
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Carcinoma,

2014
Prevention: daily aspirin and chemoprevention.
    Nature reviews. Clinical oncology, 2014, Volume: 11, Issue:4

    Topics: Acetaminophen; Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticar

2014
Statins, aspirin and risk of thromboembolic events in ovarian cancer patients.
    Gynecologic oncology, 2014, Volume: 133, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Carcinoma, Ovarian Epithelial;

2014
Drugs with potential chemopreventive properties in relation to epithelial ovarian cancer--a nationwide case-control study.
    Danish medical journal, 2015, Volume: 62, Issue:7

    Topics: Academic Dissertations as Topic; Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narc

2015
Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.
    Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:4

    Topics: Aspirin; BRCA1 Protein; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Chemoprevention; Cyclooxyge

2017
Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006, Volume: 4, Issue:7

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Case-C

2006
Analgesic drug use and risk of epithelial ovarian cancer.
    American journal of epidemiology, 2008, Jun-15, Volume: 167, Issue:12

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspir

2008
Analgesic nephropathy: clinical features and pathogenesis. Original data on the incidence and prevalence in a single renal unit.
    Acta clinica Belgica, 1998, Volume: 53, Issue:5

    Topics: Adult; Age Factors; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin

1998