Page last updated: 2024-10-23

aspirin and Epistaxis

aspirin has been researched along with Epistaxis in 38 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Epistaxis: Bleeding from the nose.

Research Excerpts

ExcerptRelevanceReference
"Comparing a patient's bleeding symptoms with those of healthy individuals is an important component of the diagnosis of bleeding disorders, but little is known about whether bleeding symptoms in healthy individuals vary by sex, race, ethnicity, age, or aspirin use."7.77Impact of sex, age, race, ethnicity and aspirin use on bleeding symptoms in healthy adults. ( Barbour, EM; Coller, BS; Khalida, C; Khazanov, NA; Levenkova, N; Mauer, AC; Tian, S; Tobin, JN, 2011)
"To quantify the relative risk of epistaxis for patients taking low-dose aspirin or clopidogrel compared to patients taking neither drug."7.75Clopidogrel versus low-dose aspirin as risk factors for epistaxis. ( Molony, NC; Rainsbury, JW, 2009)
"Epistaxis is a risk factor for ICH in middle-aged and elderly people, both independently and combined with the use of aspirin."7.71Use of aspirin, epistaxis, and untreated hypertension as risk factors for primary intracerebral hemorrhage in middle-aged and elderly people. ( Hillbom, M; Juvela, S; Saloheimo, P, 2001)
" A PubMED and Cochrane Library search was performed on 10/03/16 using, but not limited to, the search terms epistaxis, nosebleed, nose bleeding, nasal haemorrhage, nasal bleeding AND each of the following search terms: antithrombotic, anticoagulant, antiplatelet, aspirin, clopidogrel, warfarin, dabigatran, rivaroxaban, apixaban and tranexamic acid."4.93A systematic review of anti-thrombotic therapy in epistaxis. ( Musgrave, KM; Powell, J, 2016)
"Comparing a patient's bleeding symptoms with those of healthy individuals is an important component of the diagnosis of bleeding disorders, but little is known about whether bleeding symptoms in healthy individuals vary by sex, race, ethnicity, age, or aspirin use."3.77Impact of sex, age, race, ethnicity and aspirin use on bleeding symptoms in healthy adults. ( Barbour, EM; Coller, BS; Khalida, C; Khazanov, NA; Levenkova, N; Mauer, AC; Tian, S; Tobin, JN, 2011)
" A 35-year-old lady with ES taking aspirin with clopidogrel for thrombo-prophylaxis presented with massive epistaxis."3.77Massive epistaxis in a patient with Eisenmenger syndrome: illustrating the clot-versus-bleed conundrum. ( Liu, A; Pusalkar, P; Saman, H, 2011)
"To quantify the relative risk of epistaxis for patients taking low-dose aspirin or clopidogrel compared to patients taking neither drug."3.75Clopidogrel versus low-dose aspirin as risk factors for epistaxis. ( Molony, NC; Rainsbury, JW, 2009)
" The patient had been on no anticoagulation for approximately 30 years secondary to recurrent epistaxis occurring two years after starting warfarin therapy postoperatively."3.74Freedom from complications related to dual ball-and-cage mechanical valve prostheses despite thirty years without anticoagulation. ( Hipp, R; Matsumura, ME; Miller, MM, 2008)
" hypertension, aspirin use) with emergency department admission due to epistaxis."3.74Research for bleeding tendency in patients presenting with significant epistaxis. ( Buyukasik, Y; Coşkun, F; Dizdar, O; Kalyoncu, U; Karadag, O; Karakiliç, E; Onal, IK; Ozakin, E, 2007)
"Epistaxis is a risk factor for ICH in middle-aged and elderly people, both independently and combined with the use of aspirin."3.71Use of aspirin, epistaxis, and untreated hypertension as risk factors for primary intracerebral hemorrhage in middle-aged and elderly people. ( Hillbom, M; Juvela, S; Saloheimo, P, 2001)
"Epistaxis is the most common otolaryngological emergency and one-third of epistaxis patients regularly take low-dose acetylsalicylic acid (ASA) for the prevention of cardiovascular disease (CVD)."1.91The pattern of epistaxis recurrence in patients taking prophylactic acetylsalicylic acid (ASA) from a 10 year cohort. ( Hoch, S; Rudhart, S; Stanković, P; Stojković, S; Wilhelm, T, 2023)
"Recurrent epistaxis is a rare presentation of internal carotid artery C4/C5 segment pseudo-aneurysm rupture."1.40Endovascular treatment of internal carotid artery pseudo-aneurysm presenting with epistaxis. A case report. ( Bazina, A; Hucika, Z; Mišmaš, A; Pavliša, G; Poljaković, Z, 2014)
"One out of ten subjects had been treated for epistaxis by a doctor at least once in his life."1.25The frequency of epistaxis in a male population sample. ( Petruson, B; Rudin, R, 1975)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199012 (31.58)18.7374
1990's6 (15.79)18.2507
2000's9 (23.68)29.6817
2010's10 (26.32)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Stanković, P1
Hoch, S1
Rudhart, S1
Stojković, S1
Wilhelm, T1
Bazina, A1
Mišmaš, A1
Hucika, Z1
Pavliša, G1
Poljaković, Z1
Sennesael, AL1
Dogné, JM1
Spinewine, A1
Zhai, X1
Zhang, J1
Hu, Y1
Liu, G1
Stadler, RR1
Kindler, R1
Holzmann, D2
Soyka, MB2
Musgrave, KM1
Powell, J1
Miller, MM1
Hipp, R1
Matsumura, ME1
Bockeria, LA1
Skopin, II1
Kuts, EV1
Shakeel, M1
Trinidade, A1
McCluney, N1
Clive, B1
Rainsbury, JW1
Molony, NC1
Rufibach, K1
Huber, A1
Smith, J1
Siddiq, S1
Dyer, C1
Rainsbury, J1
Kim, D1
Mauer, AC1
Khazanov, NA1
Levenkova, N1
Tian, S1
Barbour, EM1
Khalida, C1
Tobin, JN1
Coller, BS1
Liu, A1
Saman, H1
Pusalkar, P1
von der Weid, NX1
Mansouri Taleghani, B1
Wuillemin, WA1
McErlane, K1
Pence, C1
Brown, NJ1
Berkowitz, RG1
Calder, NJ1
MacDonald, D1
Dizdar, O1
Onal, IK1
Ozakin, E1
Karakiliç, E1
Karadag, O1
Kalyoncu, U1
Coşkun, F1
Buyukasik, Y1
Rosove, MH1
Ho, WG1
Goldfinger, D1
Walker, AM1
Jick, H1
Hart, RG1
Pearce, LA1
Livesey, JR1
Watson, MG1
Kelly, PJ1
Kesteven, PJ1
Olofsson, K1
Dahlqvist, A1
Tay, HL1
Evans, JM1
McMahon, AD1
MacDonald, TM1
Kereiakes, DJ1
Saloheimo, P1
Juvela, S1
Hillbom, M1
Quick, AJ3
Petruson, B2
Rudin, R1
Goldsweig, HG1
Kapusta, M1
Schwartz, J1
McGarry, GU1
Veldhuizen, JA1
de Wolf, JT1
Buiter, CT1
Cats, H1
Carr, ME1
Gabriel, DA1
Diem, E1
Fritsch, P1
Heare, CR1

Reviews

3 reviews available for aspirin and Epistaxis

ArticleYear
A systematic review of anti-thrombotic therapy in epistaxis.
    Rhinology, 2016, 12-01, Volume: 54, Issue:4

    Topics: Anticoagulants; Antifibrinolytic Agents; Aspirin; Clopidogrel; Dabigatran; Disease Management; Epist

2016
Oral blockade of the platelet glycoprotein IIb/IIIa receptor: fact or fancy?
    American heart journal, 1999, Volume: 138, Issue:1 Pt 2

    Topics: Abciximab; Administration, Oral; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Be

1999
Telangiectasia: its relationship to the Minot-von Willebrand syndrome.
    The American journal of the medical sciences, 1967, Volume: 254, Issue:5

    Topics: Adolescent; Adult; Aspirin; Blood Coagulation Tests; Child; Child, Preschool; Epistaxis; Female; Gas

1967

Other Studies

35 other studies available for aspirin and Epistaxis

ArticleYear
The pattern of epistaxis recurrence in patients taking prophylactic acetylsalicylic acid (ASA) from a 10 year cohort.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2023, Volume: 280, Issue:4

    Topics: Anticoagulants; Aspirin; Cardiovascular Diseases; Epistaxis; Humans; Recurrence; Retrospective Studi

2023
Endovascular treatment of internal carotid artery pseudo-aneurysm presenting with epistaxis. A case report.
    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2014, Volume: 20, Issue:6

    Topics: Angiography, Digital Subtraction; Aspirin; Carotid Artery Injuries; Carotid Artery, Internal; Clopid

2014
Optimizing the Safe Use of Direct Oral Anticoagulants in Older Patients: A Teachable Moment.
    JAMA internal medicine, 2015, Volume: 175, Issue:10

    Topics: Acenocoumarol; Administration, Oral; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation

2015
[The characteristics and treatment in patients with epistaxis relevant to long term oral use of aspirin].
    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2015, Volume: 50, Issue:10

    Topics: Administration, Oral; Anticoagulants; Aspirin; Epistaxis; Humans

2015
The long-term fate of epistaxis patients with exposure to antithrombotic medication.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016, Volume: 273, Issue:9

    Topics: Adult; Aspirin; Cohort Studies; Epistaxis; Female; Fibrinolytic Agents; Humans; Long Term Adverse Ef

2016
Freedom from complications related to dual ball-and-cage mechanical valve prostheses despite thirty years without anticoagulation.
    Interactive cardiovascular and thoracic surgery, 2008, Volume: 7, Issue:6

    Topics: Anticoagulants; Aortic Valve; Aspirin; Atrial Fibrillation; Endocarditis, Bacterial; Epistaxis; Hear

2008
eComment: Freedom from complications related to dual ball-and-cage mechanical valve prostheses despite thirty years without anticoagulation.
    Interactive cardiovascular and thoracic surgery, 2008, Volume: 7, Issue:6

    Topics: Anticoagulants; Aortic Valve; Aspirin; Atrial Fibrillation; Endocarditis, Bacterial; Epistaxis; Hear

2008
Complementary and alternative medicine in epistaxis: a point worth considering during the patient's history.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2010, Volume: 17, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation; Complementary Therapies;

2010
Clopidogrel versus low-dose aspirin as risk factors for epistaxis.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2009, Volume: 34, Issue:3

    Topics: Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Epistaxis; Humans; Hypertension; Myocardial

2009
Is severe epistaxis associated with acetylsalicylic acid intake?
    The Laryngoscope, 2010, Volume: 120, Issue:1

    Topics: Aspirin; Cohort Studies; Epistaxis; Female; Follow-Up Studies; Humans; Length of Stay; Male; Prospec

2010
Epistaxis in patients taking oral anticoagulant and antiplatelet medication: prospective cohort study.
    The Journal of laryngology and otology, 2011, Volume: 125, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Drug Therapy, Com

2011
Impact of sex, age, race, ethnicity and aspirin use on bleeding symptoms in healthy adults.
    Journal of thrombosis and haemostasis : JTH, 2011, Volume: 9, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Contusions; Epistaxis; Ethnicity; Female; Hemo

2011
Massive epistaxis in a patient with Eisenmenger syndrome: illustrating the clot-versus-bleed conundrum.
    BMJ case reports, 2011, Aug-04, Volume: 2011

    Topics: Adult; Aspirin; Clopidogrel; Eisenmenger Complex; Epistaxis; Female; Humans; Platelet Aggregation In

2011
Severe nose bleeding after intake of acetylsalicylic acid: von Willebrand disease type 2A. Case 9.
    Hamostaseologie, 2003, Volume: 23, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Diagnosis, Differential; Epistaxis; Fibrino

2003
Epistaxis.
    Nursing, 2004, Volume: 34, Issue:8

    Topics: Aspirin; Catheterization; Emergency Treatment; Epistaxis; Humans; Hypertension; Male; Middle Aged; N

2004
Epistaxis in healthy children requiring hospital admission.
    International journal of pediatric otorhinolaryngology, 2004, Volume: 68, Issue:9

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool

2004
Adverse drug reactions as cause of admission to hospital: admissions to ear, nose, and throat departments were not mentioned.
    BMJ (Clinical research ed.), 2004, Aug-21, Volume: 329, Issue:7463

    Topics: Anticoagulants; Aspirin; Epistaxis; Hospitalization; Humans; Middle Aged; Warfarin

2004
Research for bleeding tendency in patients presenting with significant epistaxis.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2007, Volume: 18, Issue:1

    Topics: Aspirin; Biomarkers; Blood Coagulation Disorders, Inherited; Epistaxis; Family Health; Female; Hemor

2007
Ineffectiveness of aspirin and dipyridamole in the treatment of thrombotic thrombocytopenic purpura.
    Annals of internal medicine, 1982, Volume: 96, Issue:1

    Topics: Adolescent; Adult; Aged; Aspirin; Dipyridamole; Epistaxis; Epoprostenol; Female; Gastrointestinal He

1982
Predictors of bleeding during heparin therapy.
    JAMA, 1980, Sep-12, Volume: 244, Issue:11

    Topics: Adult; Aged; Alcohol Drinking; Aspirin; Dose-Response Relationship, Drug; Epistaxis; Female; Hematom

1980
In vivo antithrombotic effect of aspirin: dose versus nongastrointestinal bleeding.
    Stroke, 1993, Volume: 24, Issue:1

    Topics: Aspirin; Cerebral Hemorrhage; Dose-Response Relationship, Drug; Epistaxis; Humans

1993
Do patients with epistaxis have drug-induced platelet dysfunction?
    Clinical otolaryngology and allied sciences, 1995, Volume: 20, Issue:5

    Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arachidoni

1995
[A study of spontaneous nosebleed. Pharmaceuticals contributed probably in every third case].
    Lakartidningen, 1996, May-01, Volume: 93, Issue:18

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antihypertensive Agents; Aspir

1996
Aspirin, nonsteroidal anti-inflammatory drugs, and epistaxis. A regional record linkage case control study.
    The Annals of otology, rhinology, and laryngology, 1998, Volume: 107, Issue:8

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Case-Con

1998
Use of aspirin, epistaxis, and untreated hypertension as risk factors for primary intracerebral hemorrhage in middle-aged and elderly people.
    Stroke, 2001, Volume: 32, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; Cerebral Hemorrhage; Comorbidity; Epileps

2001
Letter: Trait vs disease.
    JAMA, 1975, Sep-22, Volume: 233, Issue:12

    Topics: Aspirin; Diagnosis, Differential; Drug Tolerance; Epistaxis; Hemorrhagic Disorders; Humans

1975
The frequency of epistaxis in a male population sample.
    Rhinology, 1975, Volume: 13, Issue:3

    Topics: Adult; Age Factors; Aspirin; Common Cold; Epistaxis; Humans; Male; Middle Aged; Stress, Physiologica

1975
Bleeding, salicylates, and prolonged prothrombin time: three case reports and a review of the literature.
    The Journal of rheumatology, 1976, Volume: 3, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Epistaxis; Female; Humans; Hypoprothrombinemias; Malabs

1976
Drug-induced epistaxis?
    Journal of the Royal Society of Medicine, 1990, Volume: 83, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Epistaxis; Female; Humans; Male; Middle Aged

1990
[Epistaxis caused by an acquired thrombocytopathy].
    Nederlands tijdschrift voor geneeskunde, 1989, Mar-25, Volume: 133, Issue:12

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Disorders; Blood Coagulati

1989
Nasal packing with porcine fatty tissue for epistaxis complicated by qualitative platelet disorders.
    The Journal of emergency medicine, 1985, Volume: 3, Issue:6

    Topics: Adipose Tissue; Aged; Animals; Aspirin; Epistaxis; Female; Hemostatic Techniques; Humans; Male; Midd

1985
Epistaxis. A clinical study with special reference to fibrinolysis.
    Acta oto-laryngologica. Supplementum, 1974, Volume: 317

    Topics: Adolescent; Adult; Age Factors; Aged; Anemia; Aspirin; Child; Cyclohexanecarboxylic Acids; Epistaxis

1974
[Salicylate poisoning by percutaneous resorption].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1973, Volume: 24, Issue:12

    Topics: Administration, Topical; Aspirin; Deafness; Epistaxis; Female; Hallucinations; Headache; Humans; Poi

1973
The Minot-von Willebrand syndrome.
    The American journal of the medical sciences, 1967, Volume: 253, Issue:5

    Topics: Adolescent; Adult; Aspirin; Blood Coagulation Tests; Child; Child, Preschool; Diagnosis, Differentia

1967
Management of epistaxis by controlled hypotension.
    The Laryngoscope, 1968, Volume: 78, Issue:11

    Topics: Ascorbic Acid; Aspirin; Epistaxis; Humans; Hypertension; Hypnotics and Sedatives; Hypotension, Contr

1968