aspirin has been researched along with Eosinophilia in 67 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Eosinophilia: Abnormal increase of EOSINOPHILS in the blood, tissues or organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed a double-blind, crossover, placebo-controlled study on the effect of fluticasone propionate (FP) treatment on chronic eosinophilic rhinosinusitis in 15 patients with aspirin-induced asthma (AIA)." | 9.08 | Intranasal fluticasone propionate for chronic eosinophilic rhinitis in patients with aspirin-induced asthma. ( Duplaga, M; Mastalerz, L; Milewski, M; Nizankowska, E; Szczeklik, A, 1997) |
| "Aspirin-exacerbated respiratory disease (AERD) is a phenotype of severe asthma, but its disease course has not been well documented compared with that of aspirin-tolerant asthma (ATA)." | 8.31 | Long-term clinical outcomes of aspirin-exacerbated respiratory disease: Real-world data from an adult asthma cohort. ( Kim, C; Lee, E; Lee, HY; Lee, Y; Park, HS; Park, RW; Woo, SD; You, SC, 2023) |
| " The current report describes a Japanese boy who underwent aspirin treatment for Kawasaki disease, and who subsequently presented with the manifestations of DIHS/DRESS syndrome." | 7.75 | Drug-induced hypersensitivity syndrome: drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome induced by aspirin treatment of Kawasaki disease. ( Fujita, A; Kawakami, T; Muto, S; Soma, Y; Takeuchi, S, 2009) |
| "Data were compared between asthmatic patients who reported exacerbations after aspirin ingestion and those who did not." | 7.73 | Chronic hyperplastic eosinophilic sinusitis as a predictor of aspirin-exacerbated respiratory disease. ( Borish, L; Hunt, J; Mascia, K; Patrie, J; Phillips, CD; Steinke, JW, 2005) |
| "Nasal polyps infiltrated with eosinophils are commonly found in chronic asthmatic patients, more frequently in those with aspirin-intolerant asthma (AIA) than aspirin-tolerant asthma (ATA)." | 7.72 | Specific immunoglobulin E for staphylococcal enterotoxins in nasal polyps from patients with aspirin-intolerant asthma. ( Kim, HJ; Kim, SH; Nahm, DH; Park, HS; Sampson, AP; Suh, CH; Suh, YJ; Yoon, SH, 2004) |
| "This study confirms the importance of eosinophil infiltration in the pathogenesis of severe or recurrent nasal polyps based on allergy and aspirin intolerance." | 7.70 | [Significance of eosinophilic granulocytes in relation to allergy and aspirin intolerance in patients with sinusitis polyposa]. ( Bittinger, F; Gosepath, J; Kaldenbach, T; Klimek, L; Mann, WJ; Schäfer, D, 1999) |
| "Aspirin-induced asthma (AIA) is frequently accompanied by nasal polyps." | 7.70 | Detection of activated eosinophils in nasal polyps of an aspirin-induced asthma patient. ( Ogata, Y; Okinaka, Y; Takahashi, M, 1999) |
| "We describe a case of eosinophilic esophagitis in a 38-year-old man with aspirin-sensitivity asthma which presented as noncardiac chest pain." | 7.69 | Chest pain in an aspirin-sensitive asthmatic patient. Eosinophilic esophagitis causing esophageal dysmotility. ( Elliott, DE; Hempel, SL, 1996) |
| "Asthma, aspirin intolerance and nasal polyps form a triad of aspirin-induced asthma (AIA)." | 7.67 | Aspirin-induced asthma and nasal polyps. ( Harada, T; Irifune, M; Matsunaga, T; Nagano, T; Ogino, S; Okawachi, I, 1986) |
| "Tissue eosinophilia is regulated by chemical attractants and activating substances of various origins and plays a major part in the chronic inflammatory state." | 5.28 | Nonallergic rhinitis with eosinophilia syndrome a precursor of the triad: nasal polyposis, intrinsic asthma, and intolerance to aspirin. ( Guyot, JL; Hsieh, V; Maria, Y; Moneret-Vautrin, DA; Mouton, C; Wayoff, M, 1990) |
| "We performed a double-blind, crossover, placebo-controlled study on the effect of fluticasone propionate (FP) treatment on chronic eosinophilic rhinosinusitis in 15 patients with aspirin-induced asthma (AIA)." | 5.08 | Intranasal fluticasone propionate for chronic eosinophilic rhinitis in patients with aspirin-induced asthma. ( Duplaga, M; Mastalerz, L; Milewski, M; Nizankowska, E; Szczeklik, A, 1997) |
| "A case of asymptomatic eosinophilia in the setting of acetylsalicylic acid (aspirin) use was presented, followed by discussion of the clinical characteristics, diagnosis, and management of drug-induced eosinophilia." | 4.98 | Drug-induced eosinophilia. ( Freeman, A; Rauscher, C, 2018) |
| " However, recently there has been some progress in elucidating the etiology of nasal polyposis, especially regarding tissue eosinophilia as well as the role of aspirin intolerance and eicosanoid mediators." | 4.82 | Current concepts in therapy of chronic rhinosinusitis and nasal polyposis. ( Gosepath, J; Mann, WJ, 2005) |
| "Recent findings supporting mechanisms that promote eosinophilic infiltration are discussed and include the following subcategories: super antigen-induced eosinophilic chronic rhinosinusitis, allergic fungal sinusitis, nonallergic fungal eosinophilic chronic rhinosinusitis, and aspirin-exacerbated eosinophilic chronic rhinosinusitis." | 4.82 | Categorization of eosinophilic chronic rhinosinusitis. ( Ferguson, BJ, 2004) |
| " Association of bronchial asthma, nasal pathology and intolerance to aspirin is a unique syndrome." | 4.75 | Aspirin intolerance--a review. ( Abrishami, MA; Thomas, J, 1977) |
| "Aspirin-exacerbated respiratory disease (AERD) is a phenotype of severe asthma, but its disease course has not been well documented compared with that of aspirin-tolerant asthma (ATA)." | 4.31 | Long-term clinical outcomes of aspirin-exacerbated respiratory disease: Real-world data from an adult asthma cohort. ( Kim, C; Lee, E; Lee, HY; Lee, Y; Park, HS; Park, RW; Woo, SD; You, SC, 2023) |
| "Nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD) asthma is characterized by chronic rhinosinusitis and intolerance of aspirin and other COX1 inhibitors." | 4.02 | Heterogeneity of lower airway inflammation in patients with NSAID-exacerbated respiratory disease. ( Bochenek, G; Gielicz, A; Jakiela, B; Plutecka, H; Przybyszowski, M; Rebane, A; Sladek, K; Soja, J, 2021) |
| " We also demonstrated that hypereosinophilia, asthma, and aspirin intolerance may increase the OR differently in eosinophilic patients." | 3.85 | Prognostic value of nasal cytology and clinical factors in nasal polyps development in patients at risk: can the beginning predict the end? ( Autilio, C; Baroni, S; Battista, M; De Corso, E; De Vita, C; Galli, J; Lucidi, D; Paludetti, G; Romanello, M, 2017) |
| "Aspirin-exacerbated respiratory disease (AERD) is an endotype of severe and eosinophilic adult asthma characterized by chronic rhinosinusitis with nasal polyps and hypersensitivity to aspirin and/or nonsteroidal anti-inflammatory drugs." | 3.81 | Dipeptidyl-peptidase 10 as a genetic biomarker for the aspirin-exacerbated respiratory disease phenotype. ( Choi, H; Kim, SH; Park, HS; Ye, YM; Yoon, MG, 2015) |
| "To demonstrate that quality-of-life outcomes after endoscopic sinus surgery are not compromised in patients with Samter's triad (asthma, nasal polyps, aspirin sensitivity) when compared to patients with eosinophilic chronic rhinosinusitis with nasal polyposis (eCRSwP) who are not aspirin sensitive." | 3.80 | Aspirin sensitivity does not compromise quality-of-life outcomes in patients with Samter's triad. ( Comer, BT; Jang, DW; Kountakis, SE; Lachanas, VA, 2014) |
| " CRSwNP was subdivided into allergic fungal rhinosinusitis (AFRS), aspirin-exacerbated respiratory disease (AERD), and other CRSwNP." | 3.80 | Impact of vitamin D deficiency upon clinical presentation in nasal polyposis. ( Mulligan, JK; Schlosser, RJ; Schmedes, GW; Soler, ZM; Storck, K, 2014) |
| " The in vivo studies on albino mice proved the purified fraction has anti-stress/anti-allergic activity against milk induced leucocytosis/eosinophilia and able to inhibit the aspirin induced gastric ulcers." | 3.80 | In vivo anti-ulcer, anti-stress, anti-allergic, and functional properties of gymnemic acid isolated from Gymnema sylvestre R Br. ( Annamalai, SK; Arun, LB; Arunachalam, AM; Arunachalam, KD; Kumar, KA, 2014) |
| " The current report describes a Japanese boy who underwent aspirin treatment for Kawasaki disease, and who subsequently presented with the manifestations of DIHS/DRESS syndrome." | 3.75 | Drug-induced hypersensitivity syndrome: drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome induced by aspirin treatment of Kawasaki disease. ( Fujita, A; Kawakami, T; Muto, S; Soma, Y; Takeuchi, S, 2009) |
| "Nasal polyps are characterized by eosinophilic infiltration, and frequently coexist with asthma, aspirin intolerance and allergy." | 3.75 | Clinical significance of eosinophilic cationic protein levels in nasal secretions of patients with nasal polyposis. ( Auo, HJ; Joo, YH; Kang, JM; Sun, DI, 2009) |
| " Often it is associated with non allergic rhinitis with eosinophilia syndrome (NARES), nasal polyposis and intolerance to Aspirin and NSAID's." | 3.74 | [Nonallergic diseases of the upper and lower airways]. ( Menz, G; Rothe, T, 2008) |
| "Data were compared between asthmatic patients who reported exacerbations after aspirin ingestion and those who did not." | 3.73 | Chronic hyperplastic eosinophilic sinusitis as a predictor of aspirin-exacerbated respiratory disease. ( Borish, L; Hunt, J; Mascia, K; Patrie, J; Phillips, CD; Steinke, JW, 2005) |
| "2%); A-polyps and bronchial asthma without aspirin intolerance (n = 19-28." | 3.73 | [Nasal polyps is not a homogenous pathology]. ( Arcimowicz, M; Balcerzak, J; Samoliński, BK, 2005) |
| "Nasal polyps infiltrated with eosinophils are commonly found in chronic asthmatic patients, more frequently in those with aspirin-intolerant asthma (AIA) than aspirin-tolerant asthma (ATA)." | 3.72 | Specific immunoglobulin E for staphylococcal enterotoxins in nasal polyps from patients with aspirin-intolerant asthma. ( Kim, HJ; Kim, SH; Nahm, DH; Park, HS; Sampson, AP; Suh, CH; Suh, YJ; Yoon, SH, 2004) |
| "Aspirin-induced asthma (AIA) is frequently accompanied by nasal polyps." | 3.70 | Detection of activated eosinophils in nasal polyps of an aspirin-induced asthma patient. ( Ogata, Y; Okinaka, Y; Takahashi, M, 1999) |
| "This study confirms the importance of eosinophil infiltration in the pathogenesis of severe or recurrent nasal polyps based on allergy and aspirin intolerance." | 3.70 | [Significance of eosinophilic granulocytes in relation to allergy and aspirin intolerance in patients with sinusitis polyposa]. ( Bittinger, F; Gosepath, J; Kaldenbach, T; Klimek, L; Mann, WJ; Schäfer, D, 1999) |
| " As lipoxin A4 (LXA4) and aspirin-triggered 15-epi-LXA4 (ATL) are emerging as endogenous "stop signals" produced in distinct pathologies including some eosinophil-related pulmonary disorders, we evaluated the impact of in situ LXA4/ATL metabolically stable analogues on allergen-induced eosinophilic pleurisy in sensitized rats." | 3.70 | Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking. ( Bandeira-Melo, C; Bozza, PT; Cordeiro, RS; Diaz, BL; Jose, PJ; Martins, MA; Serhan, CN, 2000) |
| "We describe a case of eosinophilic esophagitis in a 38-year-old man with aspirin-sensitivity asthma which presented as noncardiac chest pain." | 3.69 | Chest pain in an aspirin-sensitive asthmatic patient. Eosinophilic esophagitis causing esophageal dysmotility. ( Elliott, DE; Hempel, SL, 1996) |
| "Asthma, aspirin intolerance and nasal polyps form a triad of aspirin-induced asthma (AIA)." | 3.67 | Aspirin-induced asthma and nasal polyps. ( Harada, T; Irifune, M; Matsunaga, T; Nagano, T; Ogino, S; Okawachi, I, 1986) |
| "A 13-year-old boy affected by bursitis of the R knee and nonossifying fibroma of the distal metaphysis of the R femur, was treated in the weeks prior to surgical intervention with water-soluble aspirin tablets to relieve local pain." | 3.66 | Epithelioid granulomata in a nonossifying fibroma. The possible drug-induced mechanism. ( Comelli, A; Cozzutto, C, 1982) |
| "Eosinophilia is frequently, but not exclusively, caused by immunoglobulin (Ig)E-mediated hypersensitivity and is dominated by the associated cytokine milieu of Th2 inflammation." | 2.43 | Differential diagnosis of eosinophilic chronic rhinosinusitis. ( Ferguson, BJ; Sok, JC, 2006) |
| "Tissue eosinophilia was a prominent feature of both allergic and nonallergic CHS/NP and correlated in both subgroups with the density of GM-CSF and IL-3 mRNA+ cells." | 1.29 | Evidence for distinct cytokine expression in allergic versus nonallergic chronic sinusitis. ( Bean, DK; Cunningham, L; Hamid, Q; Hamilos, DL; Leung, DY; Schotman, E; Wood, R; Yasruel, Z, 1995) |
| "Both prednisolone and aspirin were administered with improvement of eosinophilia and partial thrombolysis." | 1.28 | [A case of hypereosinophilic syndrome followed by bronchial asthma, intraventricular thrombus, and duodenitis]. ( Aoi, K; Doi, I; Hiraga, T; Kawakami, Y; Munakata, M; Ohtsuka, Y, 1991) |
| "A 23-year-old male with bronchial asthma developed eosinophilia (eosinophils greater than 2,000/mm3) and was observed at our hospital." | 1.28 | [Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome]. ( Arai, Y; Fukushima, N; Isokane, N; Miyamoto, Y; Sano, Y; Suzuki, N, 1991) |
| "Tissue eosinophilia is regulated by chemical attractants and activating substances of various origins and plays a major part in the chronic inflammatory state." | 1.28 | Nonallergic rhinitis with eosinophilia syndrome a precursor of the triad: nasal polyposis, intrinsic asthma, and intolerance to aspirin. ( Guyot, JL; Hsieh, V; Maria, Y; Moneret-Vautrin, DA; Mouton, C; Wayoff, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (22.39) | 18.7374 |
| 1990's | 9 (13.43) | 18.2507 |
| 2000's | 26 (38.81) | 29.6817 |
| 2010's | 10 (14.93) | 24.3611 |
| 2020's | 7 (10.45) | 2.80 |
| Authors | Studies |
|---|---|
| Bangert, C | 1 |
| Villazala-Merino, S | 1 |
| Fahrenberger, M | 1 |
| Krausgruber, T | 1 |
| Bauer, WM | 1 |
| Stanek, V | 1 |
| Campion, NJ | 1 |
| Bartosik, T | 1 |
| Quint, T | 1 |
| Regelsberger, G | 1 |
| Niederberger-Leppin, V | 1 |
| Bock, C | 1 |
| Schneider, S | 1 |
| Eckl-Dorna, J | 1 |
| Lee, Y | 1 |
| Kim, C | 1 |
| Lee, E | 1 |
| Lee, HY | 1 |
| Woo, SD | 1 |
| You, SC | 1 |
| Park, RW | 1 |
| Park, HS | 4 |
| Vukadinović, T | 1 |
| Vuksanović Božarić, A | 1 |
| Vukomanović Đurđević, B | 1 |
| Radunović, M | 1 |
| Perić, A | 1 |
| McHugh, T | 1 |
| Levin, M | 1 |
| Snidvongs, K | 1 |
| Banglawala, SM | 1 |
| Sommer, DD | 1 |
| Jakiela, B | 1 |
| Soja, J | 1 |
| Sladek, K | 1 |
| Przybyszowski, M | 1 |
| Plutecka, H | 1 |
| Gielicz, A | 1 |
| Rebane, A | 1 |
| Bochenek, G | 1 |
| Badrani, JH | 1 |
| Doherty, TA | 1 |
| Ball, LL | 1 |
| Velasquez, SA | 1 |
| Al Jammal, OM | 1 |
| White, AA | 1 |
| Akuthota, P | 1 |
| De Corso, E | 1 |
| Lucidi, D | 1 |
| Battista, M | 1 |
| Romanello, M | 1 |
| De Vita, C | 1 |
| Baroni, S | 1 |
| Autilio, C | 1 |
| Galli, J | 1 |
| Paludetti, G | 1 |
| Rauscher, C | 1 |
| Freeman, A | 1 |
| Hafrén, L | 1 |
| Pajari, M | 1 |
| Vento, SI | 2 |
| Saarinen, R | 1 |
| Jang, DW | 1 |
| Comer, BT | 1 |
| Lachanas, VA | 1 |
| Kountakis, SE | 1 |
| Schlosser, RJ | 1 |
| Soler, ZM | 1 |
| Schmedes, GW | 1 |
| Storck, K | 1 |
| Mulligan, JK | 1 |
| Arun, LB | 1 |
| Arunachalam, AM | 1 |
| Arunachalam, KD | 1 |
| Annamalai, SK | 1 |
| Kumar, KA | 1 |
| Kim, SH | 2 |
| Choi, H | 1 |
| Yoon, MG | 1 |
| Ye, YM | 1 |
| Liu, T | 1 |
| Garofalo, D | 1 |
| Feng, C | 1 |
| Lai, J | 1 |
| Katz, H | 1 |
| Laidlaw, TM | 1 |
| Boyce, JA | 1 |
| Gitomer, SA | 1 |
| Fountain, CR | 1 |
| Kingdom, TT | 1 |
| Getz, AE | 1 |
| Sillau, SH | 1 |
| Katial, RK | 1 |
| Ramakrishnan, VR | 1 |
| Rothe, T | 1 |
| Menz, G | 1 |
| Wong, CW | 1 |
| Luis, S | 1 |
| Zeng, I | 1 |
| Stewart, RA | 1 |
| Sun, DI | 1 |
| Joo, YH | 1 |
| Auo, HJ | 1 |
| Kang, JM | 1 |
| Kounis, GN | 1 |
| Kounis, SA | 1 |
| Hahalis, G | 1 |
| Kounis, NG | 1 |
| Kawakami, T | 1 |
| Fujita, A | 1 |
| Takeuchi, S | 1 |
| Muto, S | 1 |
| Soma, Y | 1 |
| Szczeklik, A | 4 |
| Wu, CS | 1 |
| Sung, SF | 1 |
| Tong, SH | 1 |
| Ong, CT | 1 |
| Vieth, M | 1 |
| Müller, H | 1 |
| Stolte, M | 1 |
| Füessl, HS | 1 |
| Riccioni, G | 1 |
| Della Vecchia, R | 1 |
| Menna, V | 1 |
| Lambo, MS | 1 |
| Di Ilio, C | 1 |
| D'Orazio, N | 1 |
| Ferguson, BJ | 3 |
| Suh, YJ | 2 |
| Yoon, SH | 1 |
| Sampson, AP | 2 |
| Kim, HJ | 1 |
| Nahm, DH | 1 |
| Suh, CH | 1 |
| Cheng, TI | 1 |
| Cheng, TJ | 1 |
| Chiang, SC | 1 |
| Amrol, D | 1 |
| Murray, JJ | 1 |
| Gosepath, J | 2 |
| Mann, WJ | 2 |
| Mascia, K | 1 |
| Borish, L | 1 |
| Patrie, J | 1 |
| Hunt, J | 1 |
| Phillips, CD | 1 |
| Steinke, JW | 1 |
| Arcimowicz, M | 1 |
| Balcerzak, J | 1 |
| Samoliński, BK | 1 |
| Sok, JC | 2 |
| Adamjee, J | 1 |
| Choi, JH | 1 |
| Penrose, JF | 1 |
| Lam, BK | 1 |
| Austen, KF | 1 |
| Cazaly, AM | 1 |
| Wilson, SJ | 1 |
| Modrzyński, M | 1 |
| Mazurek, H | 1 |
| Zawisza, E | 1 |
| Chanez, P | 1 |
| Vachier, I | 1 |
| Bourdin, A | 1 |
| Halimi, L | 1 |
| Godard, P | 1 |
| Stevenson, DD | 1 |
| Simon, RA | 1 |
| Cozzutto, C | 1 |
| Comelli, A | 1 |
| Cofrancesco, E | 1 |
| Cortellaro, M | 1 |
| Pogliani, E | 1 |
| Boschetti, C | 1 |
| Salvatore, M | 1 |
| Polli, EE | 1 |
| Settipane, GA | 1 |
| Hamilos, DL | 1 |
| Leung, DY | 1 |
| Wood, R | 1 |
| Cunningham, L | 1 |
| Bean, DK | 1 |
| Yasruel, Z | 1 |
| Schotman, E | 1 |
| Hamid, Q | 1 |
| Hempel, SL | 1 |
| Elliott, DE | 1 |
| Mastalerz, L | 1 |
| Milewski, M | 1 |
| Duplaga, M | 1 |
| Nizankowska, E | 1 |
| Ogata, Y | 1 |
| Okinaka, Y | 1 |
| Takahashi, M | 1 |
| Kaldenbach, T | 1 |
| Schäfer, D | 1 |
| Bittinger, F | 1 |
| Klimek, L | 1 |
| Sanak, M | 2 |
| Bandeira-Melo, C | 1 |
| Bozza, PT | 1 |
| Diaz, BL | 1 |
| Cordeiro, RS | 1 |
| Jose, PJ | 1 |
| Martins, MA | 1 |
| Serhan, CN | 1 |
| Ertama, LO | 1 |
| Hytönen, ML | 1 |
| Wolff, CH | 1 |
| Malmberg, CH | 1 |
| Abrishami, MA | 1 |
| Thomas, J | 1 |
| Gillett, DG | 1 |
| Ford, GT | 1 |
| Ohtsuka, Y | 1 |
| Doi, I | 1 |
| Aoi, K | 1 |
| Hiraga, T | 1 |
| Munakata, M | 1 |
| Kawakami, Y | 1 |
| Suzuki, N | 1 |
| Arai, Y | 1 |
| Miyamoto, Y | 1 |
| Isokane, N | 1 |
| Fukushima, N | 1 |
| Sano, Y | 1 |
| Le Quintrec, JL | 1 |
| Bisagni-Faure, A | 1 |
| Grégoir, C | 1 |
| Menkès, CJ | 1 |
| Moneret-Vautrin, DA | 2 |
| Hsieh, V | 2 |
| Wayoff, M | 2 |
| Guyot, JL | 1 |
| Mouton, C | 1 |
| Maria, Y | 2 |
| Jankowski, R | 1 |
| Ng, SC | 1 |
| Lee, MK | 1 |
| Teh, A | 1 |
| Wardlaw, AJ | 1 |
| Kay, AB | 1 |
| Ogino, S | 1 |
| Harada, T | 1 |
| Okawachi, I | 1 |
| Irifune, M | 1 |
| Matsunaga, T | 1 |
| Nagano, T | 1 |
| Gibson, BE | 1 |
| Buchanan, MR | 1 |
| Barr, RD | 1 |
| White, JG | 1 |
| Iurenev, PN | 1 |
| Semenovich, NI | 1 |
| Winckelmann, G | 1 |
| Panush, RS | 1 |
| Franco, AE | 1 |
| Schur, PH | 1 |
| Hyde, JS | 1 |
| Floro, LD | 1 |
| Vithayasai, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Investigation of the Association Between Nasal Polyposis and Extraesophageal Reflux Disease[NCT00215787] | 20 participants (Actual) | Interventional | 2005-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Presence of Laryngopharyngeal reflux was measured by 24 hour pH impedance probe monitor per equipment manufacturer software. Two or more episodes in twenty four hours was considered positive, in accordance with published standards. (NCT00215787)
Timeframe: one year
| Intervention | participants (Number) |
|---|---|
| Lansoprazole | 15 |
17 reviews available for aspirin and Eosinophilia
| Article | Year |
|---|---|
Comorbidities associated with eosinophilic chronic rhinosinusitis: A systematic review and meta-analysis.
Topics: Aspirin; Asthma; Chronic Disease; Comorbidity; Eosinophilia; Humans; Nasal Polyps; Rhinitis; Severit | 2020 |
Cellular interactions in aspirin-exacerbated respiratory disease.
Topics: Aspirin; Asthma, Aspirin-Induced; Basophils; Bronchoconstriction; Cell Communication; Cytokines; Eic | 2021 |
Drug-induced eosinophilia.
Topics: Adult; Allergens; Aspirin; Asymptomatic Diseases; Cardiomyopathies; Drug Hypersensitivity; Eosinophi | 2018 |
Eosinophilia and coronary artery vasospasm.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Vasospasm | 2008 |
Categorization of eosinophilic chronic rhinosinusitis.
Topics: Aspergillosis, Allergic Bronchopulmonary; Aspirin; Child; Chronic Disease; Eosinophilia; Eosinophils | 2004 |
Alternative medical treatment strategies for chronic hyperplastic eosinophilic sinusitis.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Antifungal Agents; Aspirin; Chronic Disease; Eosino | 2005 |
Current concepts in therapy of chronic rhinosinusitis and nasal polyposis.
Topics: Anti-Bacterial Agents; Antifungal Agents; Aspirin; Chronic Disease; Endoscopy; Eosinophilia; Histami | 2005 |
Differential diagnosis of eosinophilic chronic rhinosinusitis.
Topics: Animals; Aspirin; Chronic Disease; Diagnosis, Differential; Eosinophilia; Fungi; Humans; Hypersensit | 2006 |
[Difficult asthma].
Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2006 |
Selection of patients for aspirin desensitization treatment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Desensitization, Immunologic; Drug Hyperse | 2006 |
Differential diagnosis of eosinophilic chronic rhinosinusitis.
Topics: Aspirin; Chronic Disease; Diagnosis, Differential; Eosinophilia; Eosinophils; Humans; Mycoses; Rhini | 2007 |
Genetic mechanisms in aspirin-induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; Eosinophilia; Female; Hum | 2000 |
Genetics of aspirin induced asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Eosinophilia; G | 2000 |
Aspirin intolerance--a review.
Topics: Adolescent; Adult; Age Factors; Aged; Angioedema; Aspirin; Asthma; Blood Coagulation; Child; Child, | 1977 |
Drug-induced lung disease.
Topics: Alveolitis, Extrinsic Allergic; Antineoplastic Agents; Aspirin; Bronchial Spasm; Eosinophilia; Human | 1978 |
The role of the eosinophil in the pathogenesis of asthma.
Topics: Adrenal Cortex Hormones; Antigens, Surface; Aspirin; Asthma; Blood Proteins; Bronchi; Chemotactic Fa | 1987 |
[Blood platelet diseases].
Topics: Adenosine Diphosphate; Afibrinogenemia; Aspirin; Blood Platelet Disorders; Blood Platelets; Diagnosi | 1973 |
2 trials available for aspirin and Eosinophilia
| Article | Year |
|---|---|
[Nasal provocation test with lysine-aspirin in diagnosis of nonallergic rhinitis with eosinophilia].
Topics: Administration, Intranasal; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; D | 2006 |
Intranasal fluticasone propionate for chronic eosinophilic rhinitis in patients with aspirin-induced asthma.
Topics: Administration, Intranasal; Adult; Androstadienes; Anti-Allergic Agents; Aspirin; Asthma; Chronic Di | 1997 |
48 other studies available for aspirin and Eosinophilia
| Article | Year |
|---|---|
Comprehensive Analysis of Nasal Polyps Reveals a More Pronounced Type 2 Transcriptomic Profile of Epithelial Cells and Mast Cells in Aspirin-Exacerbated Respiratory Disease.
Topics: Aspirin; Asthma, Aspirin-Induced; Chronic Disease; Eosinophilia; Epithelial Cells; Humans; Inflammat | 2022 |
Long-term clinical outcomes of aspirin-exacerbated respiratory disease: Real-world data from an adult asthma cohort.
Topics: Aspirin; Asthma; Asthma, Aspirin-Induced; Eosinophilia; Eosinophils; Humans; Sinusitis | 2023 |
Angiogenesis and eosinophilia in the nasal mucosa of patients with different clinical phenotypes of chronic rhinosinusitis.
Topics: Aspirin; Chronic Disease; Cross-Sectional Studies; Eosinophilia; Humans; Nasal Mucosa; Nasal Polyps; | 2023 |
Heterogeneity of lower airway inflammation in patients with NSAID-exacerbated respiratory disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Bronchoalveolar L | 2021 |
Atypical eosinophilic granulomatosis with polyangiitis with spontaneous aspirin reactivity and immunoglobulin E-mediated anaphylaxis.
Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; C-Reactive Protein; CD | 2021 |
Prognostic value of nasal cytology and clinical factors in nasal polyps development in patients at risk: can the beginning predict the end?
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Eosinophilia; Female; Humans; Male; Middle Aged; Nasal Muc | 2017 |
Otitis media with effusion in aspirin-exacerbated respiratory disease patients-A series of 22 cases.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Eosino | 2018 |
Aspirin sensitivity does not compromise quality-of-life outcomes in patients with Samter's triad.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chronic Disease; | 2014 |
Impact of vitamin D deficiency upon clinical presentation in nasal polyposis.
Topics: Age Factors; Allergens; Antigens, Fungal; Aspirin; Black or African American; Cholecalciferol; Chron | 2014 |
In vivo anti-ulcer, anti-stress, anti-allergic, and functional properties of gymnemic acid isolated from Gymnema sylvestre R Br.
Topics: Animals; Anti-Allergic Agents; Anti-Bacterial Agents; Anti-Ulcer Agents; Antioxidants; Aspirin; Chro | 2014 |
Dipeptidyl-peptidase 10 as a genetic biomarker for the aspirin-exacerbated respiratory disease phenotype.
Topics: Adipokines; Adult; Aspirin; Asthma, Aspirin-Induced; Case-Control Studies; Chitinase-3-Like Protein | 2015 |
Platelet-driven leukotriene C4-mediated airway inflammation in mice is aspirin-sensitive and depends on T prostanoid receptors.
Topics: Allergens; Animals; Aspirin; Asthma; Blood Platelets; Bone Marrow Transplantation; Bronchoalveolar L | 2015 |
Clinical Examination of Tissue Eosinophilia in Patients with Chronic Rhinosinusitis and Nasal Polyposis.
Topics: Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Eosinophilia; Female; Humans; Male; Middle | 2016 |
[Nonallergic diseases of the upper and lower airways].
Topics: Aspirin; Asthma; Bronchitis; Diagnosis, Differential; Drug Hypersensitivity; Eosinophilia; Humans; I | 2008 |
Clinical significance of eosinophilic cationic protein levels in nasal secretions of patients with nasal polyposis.
Topics: Adult; Aged; Antimicrobial Cationic Peptides; Aspirin; Asthma; Drug Hypersensitivity; Eosinophilia; | 2009 |
Coronary artery spasm associated with eosinophilia: another manifestation of Kounis syndrome?
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Vasospasm | 2009 |
Drug-induced hypersensitivity syndrome: drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome induced by aspirin treatment of Kawasaki disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child, Preschool; Drug Hypersensitivity; Eosinophi | 2009 |
Anti-interleukin-5 therapy and severe asthma.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aspirin; Asthma; Eosinophilia; Humans; In | 2009 |
Multiple cerebral infarctions related to famotidine-induced eosinophilia.
Topics: Acarbose; Adrenergic alpha-1 Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulc | 2012 |
Can the diagnosis of NSAID-induced or Hp-associated gastric ulceration be predicted from histology?
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Comorbidity; Diagnosis, Differential | 2002 |
[Heartburn without esophagitis. Symptoms more important than the finding?].
Topics: Androstadienes; Antacids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ul | 2003 |
[Antileukotrienes in the therapy of bronchial asthma].
Topics: Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Aspirin; Asthma; Asthma, E | 2003 |
Specific immunoglobulin E for staphylococcal enterotoxins in nasal polyps from patients with aspirin-intolerant asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Enterotoxins; Eosinophi | 2004 |
Association of aspirin with eosinophilia in peripheral blood.
Topics: Aged; Antiparkinson Agents; Aspirin; Eosinophilia; Humans; Levodopa; Male; Parkinson Disease; Platel | 2004 |
Chronic hyperplastic eosinophilic sinusitis as a predictor of aspirin-exacerbated respiratory disease.
Topics: Adult; Aspirin; Asthma; Case-Control Studies; Chronic Disease; Cohort Studies; Drug Hypersensitivity | 2005 |
[Nasal polyps is not a homogenous pathology].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Eosino | 2005 |
Expression of 5-lipoxygenase and cyclooxygenase pathway enzymes in nasal polyps of patients with aspirin-intolerant asthma.
Topics: Adolescent; Adult; Aged; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Cyclooxygenase Inhibitors; Eo | 2006 |
Epithelioid granulomata in a nonossifying fibroma. The possible drug-induced mechanism.
Topics: Adolescent; Aspirin; Bone Diseases; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Femoral Neo | 1982 |
Response to vincristine treatment in a case of idiopathic hypereosinophilic syndrome with multiple clinical manifestations.
Topics: Aspirin; Eosinophilia; Heart Failure; Hepatomegaly; Humans; Hypoproteinemia; Malabsorption Syndromes | 1984 |
Aspirin intolerance presenting as chronic rhinitis.
Topics: Aspirin; Chronic Disease; Diagnosis, Differential; Drug Hypersensitivity; Eosinophilia; Female; Head | 1980 |
Evidence for distinct cytokine expression in allergic versus nonallergic chronic sinusitis.
Topics: Adolescent; Adult; Aspirin; Cell Movement; Cytokines; Drug Hypersensitivity; Eosinophilia; Eosinophi | 1995 |
Chest pain in an aspirin-sensitive asthmatic patient. Eosinophilic esophagitis causing esophageal dysmotility.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chest Pain; Eosinophilia; Esophagea | 1996 |
Detection of activated eosinophils in nasal polyps of an aspirin-induced asthma patient.
Topics: Adrenal Cortex Hormones; Aspirin; Asthma; Biopsy, Needle; Eosinophilia; Eosinophils; Follow-Up Studi | 1999 |
[Significance of eosinophilic granulocytes in relation to allergy and aspirin intolerance in patients with sinusitis polyposa].
Topics: Adult; Aged; Aspirin; Drug Hypersensitivity; Eosinophilia; Eosinophils; Female; Humans; Male; Middle | 1999 |
Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking.
Topics: Allergens; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Mig | 2000 |
Nasal polyposis: clinical course during 20 years.
Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Aspirin; Biopsy; D | 2000 |
[A case of hypereosinophilic syndrome followed by bronchial asthma, intraventricular thrombus, and duodenitis].
Topics: Adult; Aspirin; Asthma; Duodenitis; Eosinophilia; Heart Diseases; Humans; Male; Myocarditis; Prednis | 1991 |
[Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome].
Topics: Adult; Age Factors; Angina Pectoris; Aspirin; Asthma; Churg-Strauss Syndrome; Eosinophilia; Humans; | 1991 |
[Eosinophilic arthritis and intolerance to aspirin (Widal's syndrome)].
Topics: Aged; Arthritis; Aspirin; Drug Hypersensitivity; Eosinophilia; Female; Humans; Syndrome | 1991 |
Nonallergic rhinitis with eosinophilia syndrome a precursor of the triad: nasal polyposis, intrinsic asthma, and intolerance to aspirin.
Topics: Adolescent; Adult; Aspirin; Asthma; Child; Drug Tolerance; Eosinophilia; Female; Humans; Male; Middl | 1990 |
[NARES syndrome. A developing link in the Fernand-Widal triad].
Topics: Adult; Aspirin; Asthma; Autonomic Nervous System Diseases; Eosinophilia; Female; Humans; Male; Middl | 1989 |
Acute organic brain syndrome due to drug-induced eosinophilia.
Topics: Acetaminophen; Aged; Anti-Bacterial Agents; Aspirin; Drugs, Chinese Herbal; Eosinophilia; Humans; Ma | 1989 |
Aspirin-induced asthma and nasal polyps.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Eosinophilia; Female; Humans; Immunoglobulin E; Male; | 1986 |
Primary thrombocythaemia in childhood: symptomatic episodes and their relationship to thromboxane A2, 6-keto-PGE1 and 12-hydroxy-eicosatetraenoic acid production: a case report.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 6-Ketoprostaglandin F1 alpha; Alprostadil; Arachidonate | 1987 |
Lung disease caused by drugs.
Topics: Aspirin; Asthma; Contraceptives, Oral; Drug-Related Side Effects and Adverse Reactions; Eosinophilia | 1969 |
[Desensitization therapy in myocardial infarct].
Topics: Adrenal Glands; Amines; Aminopyrine; Aspirin; Autoimmune Diseases; Desensitization, Immunologic; Dip | 1970 |
Rheumatoid arthritis associated with eosinophilia.
Topics: Aged; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Aspirin; Complement System Proteins; Eosino | 1971 |
Chronic and high risk asthma in children.
Topics: Adolescent; Adrenal Cortex Hormones; Aerosols; Airway Obstruction; Aspergillosis; Aspirin; Asthma; B | 1972 |