Page last updated: 2024-10-23

aspirin and Endocarditis, Bacterial

aspirin has been researched along with Endocarditis, Bacterial in 35 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Endocarditis, Bacterial: Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.

Research Excerpts

ExcerptRelevanceReference
"When myocardial infarction is due to coronary embolism from endocarditic valves standard thrombolysis regimes should be avoided."5.29Acute coronary embolism complicating aortic valve endocarditis treated with streptokinase and aspirin. A case report. ( Connolly, DL; Crowley, JJ; Dardas, PS; Kenny, A; Petch, MC, 1994)
"There was a trend toward excess bleeding in long-term aspirin recipients, compared with placebo recipients (P = ."5.13Effect of long-term aspirin use on embolic events in infective endocarditis. ( Chan, KL; Cujec, B; Dumesnil, JG; Jue, J; Robinson, T; Sanfilippo, AJ; Tam, J; Turek, M; Williams, K, 2008)
"In endocarditis patients already receiving antibiotic treatment, the addition of aspirin does not appear to reduce the risk of embolic events and is likely associated with an increased risk of bleeding."5.10A randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis. ( Chan, KL; Cujec, B; Dumesnil, JG; Jue, J; Moher, D; Robinson, TI; Sanfilippo, AJ; Turek, MA, 2003)
" The patient had been on no anticoagulation for approximately 30 years secondary to recurrent epistaxis occurring two years after starting warfarin therapy postoperatively."3.74Freedom from complications related to dual ball-and-cage mechanical valve prostheses despite thirty years without anticoagulation. ( Hipp, R; Matsumura, ME; Miller, MM, 2008)
"Because thrombus formation at the site of endothelial injury has been thought to be a critical step in the pathogenesis of bacterial endocarditis, the effect of aspirin on experimental valvular thrombosis and bacterial endocarditis in rabbits was evaluated."3.65Effect of aspirin on thrombogenesis and on production of experimental aortic valvular Streptococcus viridans endocarditis in rabbits. ( Carrizosa, J; Levison, ME; Rubin, W; Schick, PK; Tanphaichitra, D, 1977)
"Aspirin did not increase bleeding in SA positive patients."1.72Staphylococcus aureus increases platelet reactivity in patients with infective endocarditis. ( Akhyari, P; Barth, M; Dannenberg, L; Helten, C; Hoffmann, T; Hohlfeld, T; Huhn, R; Kelm, M; Levkau, B; Lichtenberg, A; M'Pembele, R; Mourikis, P; Naguib, D; Petzold, T; Polzin, A; Sixt, S; Zako, S; Zeus, T, 2022)
"Here is a case of a female with patent ductus arteriosus, who was apparently in quite good state of health and gave birth to six offsprings without herself having any problem."1.48Patent Ductus Arteriosus with Infective Vegetations in Grandmultipara. ( Siddiqa, A; Sohail, N, 2018)
"Embolism is a dreaded complication of infective endocarditis (IE)."1.34Impact of prior antiplatelet therapy on risk of embolism in infective endocarditis. ( Anavekar, NS; Baddour, LM; Chandrasekaran, K; Haddad, C; Khandaker, MH; Mirzoyev, Z; Steckelberg, JM; Tleyjeh, IM; Wilson, WR, 2007)
" We sought to determine (i) whether ASA dosage influences the development of vegetations and (ii) whether ASA given with antimicrobial therapy improves the treatment outcome of infective endocarditis."1.29Influence of aspirin on development and treatment of experimental Staphylococcus aureus endocarditis. ( Marangos, MN; Nicolau, DP; Nightingale, CH; Quintiliani, R, 1995)
"When myocardial infarction is due to coronary embolism from endocarditic valves standard thrombolysis regimes should be avoided."1.29Acute coronary embolism complicating aortic valve endocarditis treated with streptokinase and aspirin. A case report. ( Connolly, DL; Crowley, JJ; Dardas, PS; Kenny, A; Petch, MC, 1994)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19905 (14.29)18.7374
1990's9 (25.71)18.2507
2000's11 (31.43)29.6817
2010's7 (20.00)24.3611
2020's3 (8.57)2.80

Authors

AuthorsStudies
Polzin, A1
Dannenberg, L1
M'Pembele, R1
Mourikis, P1
Naguib, D1
Zako, S1
Helten, C1
Petzold, T1
Levkau, B1
Hohlfeld, T1
Barth, M1
Zeus, T1
Sixt, S1
Huhn, R1
Akhyari, P1
Lichtenberg, A1
Kelm, M1
Hoffmann, T1
Madias, JE3
Dahl, A1
Iversen, K1
Fosbol, E1
Chamat, S1
Bruun, NE1
Yang, Y1
Qidwai, U1
Burton, BJL1
Canepa, C1
Cahill, TJ1
Prendergast, BD1
Siddiqa, A1
Sohail, N1
Veloso, TR1
Oechslin, F1
Que, YA1
Moreillon, P1
Entenza, JM1
Mancini, S1
Miller, MM1
Hipp, R1
Matsumura, ME1
Bockeria, LA1
Skopin, II1
Kuts, EV1
Eisen, DP1
Corey, GR1
McBryde, ES1
Fowler, VG1
Miro, JM1
Cabell, CH1
Street, AC1
Paiva, MG1
Ionac, A1
Tan, RS1
Tribouilloy, C1
Pachirat, O1
Jones, SB1
Chipigina, N1
Naber, C1
Pan, A1
Ravasio, V1
Gattringer, R1
Chu, VH1
Bayer, AS2
Caylan, R1
Keske, S1
Durmaz, T1
Keles, T1
Tasyaran, MA1
Child, N1
Anjum, N1
Keohane, SG1
Cooper, HL1
Hayek, E1
Griffin, B1
Meimoun, P1
Mainardi, JL1
Berrebi, A1
Marino, JP1
Waldmann, T1
Carpentier, A1
Chan, KL2
Dumesnil, JG2
Cujec, B2
Sanfilippo, AJ2
Jue, J2
Turek, MA1
Robinson, TI1
Moher, D1
Homma, S1
Grahame-Clarke, C1
STERNE, J1
AUBERTIN, E1
Connolly, DL2
Choudhury, A1
Davis, RC1
Lip, GY1
Anavekar, NS2
Tleyjeh, IM1
Mirzoyev, Z1
Steckelberg, JM1
Haddad, C1
Khandaker, MH1
Wilson, WR1
Chandrasekaran, K1
Baddour, LM1
Tam, J1
Turek, M1
Robinson, T1
Williams, K1
Nicolau, DP3
Marangos, MN1
Nightingale, CH3
Quintiliani, R2
Dardas, PS1
Crowley, JJ1
Kenny, A1
Petch, MC1
Ford, I1
Douglas, CW1
Preston, FE1
Lawless, A1
Hampton, KK1
Freeman, CD1
Coe, CJ1
Maderazo, EG1
Cooper, BW1
Zuckerman, GR1
Tessier, PR1
Kupferwasser, LI1
Yeaman, MR1
Shapiro, SM1
Nast, CC1
Sullam, PM1
Filler, SG1
Levison, ME1
Carrizosa, J1
Tanphaichitra, D1
Schick, PK1
Rubin, W1
Taha, TH1
Durrant, SS1
Mazeika, PK1
Nihoyannopoulos, P1
Oakley, CM1
Constable, P1
Saraiva, LR1
Menge, P1
Rodrigues, R1
de França, NA1
Barros, GS1
Brindeiro Filho, D1
Hasegawa, M1
Tomioka, S1

Reviews

4 reviews available for aspirin and Endocarditis, Bacterial

ArticleYear
A guide to anticoagulation and endocarditis prophylaxis during cutaneous surgery.
    Clinical and experimental dermatology, 2010, Volume: 35, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Anticoagulants; Aspirin; Calcium Ch

2010
Toward reducing embolic complications from endocarditis.
    Journal of the American College of Cardiology, 2003, Sep-03, Volume: 42, Issue:5

    Topics: Aspirin; Embolism; Endocarditis, Bacterial; Humans; Incidence; Platelet Aggregation Inhibitors; Surv

2003
[THE CURRENT TREATMENT OF ACUTE ARTICULAR RHEUMATISM].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1964, Volume: 141

    Topics: Aspirin; Convalescence; Endocarditis; Endocarditis, Bacterial; Humans; Immunotherapy, Active; Penici

1964
An ounce of prevention. Toward preventing gastrointestinal endoscopic complications.
    Gastrointestinal endoscopy clinics of North America, 1996, Volume: 6, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Anticoagulants; Aspirin; Diagnostic

1996

Trials

3 trials available for aspirin and Endocarditis, Bacterial

ArticleYear
A randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis.
    Journal of the American College of Cardiology, 2003, Sep-03, Volume: 42, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Aspirin; Double-Blind Method; Drug Therapy, Combination; Echocardiograp

2003
Effect of long-term aspirin use on embolic events in infective endocarditis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Jan-01, Volume: 46, Issue:1

    Topics: Aged; Aspirin; Embolism; Endocarditis, Bacterial; Female; Hemorrhage; Humans; Male; Middle Aged; Pro

2008
Aspirin to prevent growth of vegetations and cerebral emboli in infective endocarditis.
    Journal of internal medicine, 1992, Volume: 231, Issue:5

    Topics: Adult; Aged; Aspirin; Brain; Echocardiography; Endocarditis, Bacterial; Female; Humans; Intracranial

1992

Other Studies

28 other studies available for aspirin and Endocarditis, Bacterial

ArticleYear
Staphylococcus aureus increases platelet reactivity in patients with infective endocarditis.
    Scientific reports, 2022, 07-28, Volume: 12, Issue:1

    Topics: Aspirin; Coagulase; Cohort Studies; Endocarditis, Bacterial; Humans; Pilot Projects; Platelet Aggreg

2022
Do Aspirin and/or Other Antiplatelet Agents Prevent Infective Endocarditis in Patients With Enterococcus faecalis Bacteremia?
    Journal of the American College of Cardiology, 2019, 11-12, Volume: 74, Issue:19

    Topics: Aspirin; Bacteremia; Endocarditis; Endocarditis, Bacterial; Enterococcus faecalis; Humans; Platelet

2019
Reply: Enterococcus faecalis Infective Endocarditis.
    Journal of the American College of Cardiology, 2019, 11-12, Volume: 74, Issue:19

    Topics: Aspirin; Bacteremia; Endocarditis; Endocarditis, Bacterial; Enterococcus faecalis; Humans; Platelet

2019
Readers' Comments: Aspirin and/or Other Antiplatelet Agents for the Prevention of Infective Endocarditis.
    The American journal of cardiology, 2020, 05-01, Volume: 125, Issue:9

    Topics: Aspirin; Endocarditis, Bacterial; Humans; Platelet Aggregation Inhibitors

2020
Bilateral, vertical supranuclear gaze palsy following unilateral midbrain infarct.
    BMJ case reports, 2020, Nov-04, Volume: 13, Issue:11

    Topics: Aspirin; Atrial Fibrillation; Betacoronavirus; Blindness; Brain Stem Infarctions; Coronavirus Infect

2020
Aspirin for the Prevention of Infective Endocarditis?
    Journal of the American College of Cardiology, 2017, 08-22, Volume: 70, Issue:8

    Topics: Aspirin; Endocarditis; Endocarditis, Bacterial; Humans

2017
Reply: Aspirin for the Prevention of Infective Endocarditis?
    Journal of the American College of Cardiology, 2017, 08-22, Volume: 70, Issue:8

    Topics: Aspirin; Endocarditis; Endocarditis, Bacterial; Humans

2017
Patent Ductus Arteriosus with Infective Vegetations in Grandmultipara.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018, Volume: 28, Issue:9

    Topics: Adult; Aspirin; Ductus Arteriosus, Patent; Echocardiography; Endocarditis, Bacterial; Female; Fever;

2018
Aspirin plus ticlopidine prevented experimental endocarditis due to Enterococcus faecalis and Streptococcus gallolyticus.
    Pathogens and disease, 2015, Volume: 73, Issue:8

    Topics: Animals; Aspirin; Disease Models, Animal; Endocarditis, Bacterial; Enterococcus faecalis; Female; Gr

2015
Freedom from complications related to dual ball-and-cage mechanical valve prostheses despite thirty years without anticoagulation.
    Interactive cardiovascular and thoracic surgery, 2008, Volume: 7, Issue:6

    Topics: Anticoagulants; Aortic Valve; Aspirin; Atrial Fibrillation; Endocarditis, Bacterial; Epistaxis; Hear

2008
eComment: Freedom from complications related to dual ball-and-cage mechanical valve prostheses despite thirty years without anticoagulation.
    Interactive cardiovascular and thoracic surgery, 2008, Volume: 7, Issue:6

    Topics: Anticoagulants; Aortic Valve; Aspirin; Atrial Fibrillation; Endocarditis, Bacterial; Epistaxis; Hear

2008
Reduced valve replacement surgery and complication rate in Staphylococcus aureus endocarditis patients receiving acetyl-salicylic acid.
    The Journal of infection, 2009, Volume: 58, Issue:5

    Topics: Aged; Aspirin; Cohort Studies; Embolism; Endocarditis, Bacterial; Female; Heart Failure; Heart Valve

2009
A case of Brucella endocarditis in association with superficial femoral artery thrombus.
    Tropical doctor, 2009, Volume: 39, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Aspirin; Brucellosis; Echocardiography; Endocarditis, Bacterial; Femor

2009
Mitral valve prolapse: old beliefs yield to new knowledge.
    Cleveland Clinic journal of medicine, 2002, Volume: 69, Issue:11

    Topics: Adrenergic beta-Antagonists; Antibiotic Prophylaxis; Anticoagulants; Arrhythmias, Cardiac; Aspirin;

2002
[Staphylococcus epidermidis infective endocarditis after mitral surgery, successfully treated with aspirin and antibiotics: a case report].
    Annales de cardiologie et d'angeiologie, 2000, Volume: 49, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Aspirin; Endocarditis, Bacterial; Female; Humans; Mitral Valve; Platel

2000
[New method of administration of aspirin in acute articular rheumatism].
    Archives des maladies du coeur et des vaisseaux, 1954, Volume: 47, Issue:3

    Topics: Aspirin; Endocarditis; Endocarditis, Bacterial; Humans; Rheumatic Fever

1954
A randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis.
    Journal of the American College of Cardiology, 2004, Mar-17, Volume: 43, Issue:6

    Topics: Aspirin; Endocarditis, Bacterial; Hemorrhage; Humans; Randomized Controlled Trials as Topic; Thrombo

2004
Impact of prior antiplatelet therapy on risk of embolism in infective endocarditis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, May-01, Volume: 44, Issue:9

    Topics: Aged; Aspirin; Clopidogrel; Dipyridamole; Dose-Response Relationship, Drug; Drug Administration Sche

2007
Influence of aspirin on development and treatment of experimental Staphylococcus aureus endocarditis.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Aorta; Aspirin; Dose-Response Relationship, Drug; Endocarditis, Bact

1995
Acute coronary embolism complicating aortic valve endocarditis treated with streptokinase and aspirin. A case report.
    The Journal of heart valve disease, 1994, Volume: 3, Issue:3

    Topics: Aortic Valve; Aspirin; Embolism; Endocarditis, Bacterial; Gastrointestinal Hemorrhage; Heart Valve D

1994
Mechanisms of platelet aggregation by Streptococcus sanguis, a causative organism in infective endocarditis.
    British journal of haematology, 1993, Volume: 84, Issue:1

    Topics: Agglutination; Aspirin; Blood Platelets; Cells, Cultured; Endocarditis, Bacterial; Humans; Platelet

1993
Reduction of bacterial titers by low-dose aspirin in experimental aortic valve endocarditis.
    Infection and immunity, 1993, Volume: 61, Issue:4

    Topics: Animals; Aortic Valve; Aspirin; Bacterial Adhesion; Endocarditis, Bacterial; Rabbits; Staphylococcus

1993
Beneficial effect of combination antiplatelet therapy on the development of experimental Staphylococcus aureus endocarditis.
    International journal of antimicrobial agents, 1999, Volume: 11, Issue:2

    Topics: Animals; Aspirin; Drug Therapy, Combination; Endocarditis, Bacterial; Female; Platelet Aggregation I

1999
Acetylsalicylic acid reduces vegetation bacterial density, hematogenous bacterial dissemination, and frequency of embolic events in experimental Staphylococcus aureus endocarditis through antiplatelet and antibacterial effects.
    Circulation, 1999, Jun-01, Volume: 99, Issue:21

    Topics: Animals; Anti-Bacterial Agents; Aspirin; Colony Count, Microbial; Embolism; Endocarditis, Bacterial;

1999
Effect of aspirin on thrombogenesis and on production of experimental aortic valvular Streptococcus viridans endocarditis in rabbits.
    Blood, 1977, Volume: 49, Issue:4

    Topics: Animals; Aortic Valve; Aspirin; Endocarditis, Bacterial; Female; Rabbits; Streptococcus; Thrombosis

1977
Treatment of bacterial endocarditis in cattle.
    Journal of the American Veterinary Medical Association, 1991, Aug-01, Volume: 199, Issue:3

    Topics: Animals; Aspirin; Cattle; Cattle Diseases; Endocarditis, Bacterial; Heparin

1991
[Evolutive aspect of the echocardiographic image of the vegetation in tricuspid valve endocarditis cured with clinical treatment. A case report].
    Arquivos brasileiros de cardiologia, 1988, Volume: 51, Issue:5

    Topics: Aspirin; Cefotaxime; Child; Echocardiography; Endocarditis, Bacterial; Gentamicins; Humans; Male; St

1988
[Bacterial endocarditis].
    Naika. Internal medicine, 1971, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Aspirin; Endocarditis, Bacterial; Female; Humans; Male; Middle Aged; Penicillins;

1971