aspirin has been researched along with Encephalitis in 10 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Encephalitis: Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aspirin is a non-steroidal anti-inflammatory drug that is an irreversible inhibitor of both cyclooxygenase (COX)-1 and COX-2, It stimulates endogenous production of anti-inflammatory regulatory 'braking signals', including lipoxins, which dampen the inflammatory response and reduce levels of inflammatory biomarkers, including C-reactive protein, tumor necrosis factor-α and interleukin (IL)--6, but not negative immunoregulatory cytokines, such as IL-4 and IL-10." | 2.49 | Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness. ( Berk, M; Davey, CG; Dean, O; Drexhage, H; Maes, M; McNeil, JJ; Moylan, S; O'Neil, A; Sanna, L, 2013) |
| " We examined the possibility that concurrent blockade of free radicals and prostaglandin E(2) (PGE(2))-mediated inflammation might constitute a safe and effective therapeutic approach to ALS." | 1.38 | Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis. ( Cho, W; Gwag, BJ; Im, DS; Lee, JH; Lee, JK; Lee, YA; Lee, YB; Shin, JH; Springer, JE; Yun, BS, 2012) |
| "Moyamoya disease is a progressive, unilateral, or bilateral carotid artery stenosis of unknown etiology." | 1.35 | Moyamoya disease in an 8-year-old boy presenting with weakness. ( Johnson, LH; Tenney, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berk, M | 1 |
| Dean, O | 1 |
| Drexhage, H | 1 |
| McNeil, JJ | 1 |
| Moylan, S | 1 |
| O'Neil, A | 1 |
| Davey, CG | 1 |
| Sanna, L | 1 |
| Maes, M | 1 |
| Liptai, Z | 1 |
| Ivády, B | 1 |
| Barsi, P | 1 |
| Várallyay, G | 1 |
| Rudas, G | 1 |
| Fogarasi, A | 1 |
| Drochioiu, G | 1 |
| Tudorachi, L | 1 |
| Murariu, M | 1 |
| Tenney, J | 1 |
| Johnson, LH | 1 |
| Leroux, P | 1 |
| Hennebert, C | 1 |
| Catteau, J | 1 |
| Legros, H | 1 |
| Hennebert, O | 1 |
| Laudenbach, V | 1 |
| Marret, S | 1 |
| Wang, F | 1 |
| Zhai, H | 1 |
| Huang, L | 1 |
| Li, H | 1 |
| Xu, Y | 1 |
| Qiao, X | 1 |
| Sun, S | 1 |
| Wu, Y | 1 |
| Shin, JH | 1 |
| Lee, YA | 1 |
| Lee, JK | 1 |
| Lee, YB | 1 |
| Cho, W | 1 |
| Im, DS | 1 |
| Lee, JH | 1 |
| Yun, BS | 1 |
| Springer, JE | 1 |
| Gwag, BJ | 1 |
| Wahner, AD | 1 |
| Bronstein, JM | 1 |
| Bordelon, YM | 1 |
| Ritz, B | 1 |
| Kang, ES | 1 |
| Olson, G | 1 |
| Jabbour, JT | 1 |
| Solomon, SS | 1 |
| Heimberg, M | 1 |
| Sabesin, S | 1 |
| Griffith, JF | 1 |
| Brune, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Salicylic Augmentation in Depression[NCT03152409] | Phase 2 | 74 participants (Anticipated) | Interventional | 2018-11-15 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for aspirin and Encephalitis
| Article | Year |
|---|---|
Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Encephalitis; Humans; Mental Disorders; O | 2013 |
[Analgesics: pharmacologic properties as a basis for rational therapy].
Topics: Acetylcholine; Aminopyrine; Analgesics; Animals; Aspirin; Central Nervous System; Dogs; Encephalitis | 1978 |
8 other studies available for aspirin and Encephalitis
| Article | Year |
|---|---|
Mild encephalitis/encephalopathy with a reversible splenial lesion in children.
Topics: Adolescent; Anti-Inflammatory Agents; Antipyretics; Aspirin; Brain; Brain Edema; Child; Corpus Callo | 2013 |
NOSH aspirin may have a protective role in Alzheimer's disease.
Topics: Alzheimer Disease; Aspirin; Disulfides; Encephalitis; Humans; Models, Biological; Nitrates | 2015 |
Moyamoya disease in an 8-year-old boy presenting with weakness.
Topics: Anti-Inflammatory Agents; Aspirin; Attention Deficit Disorder with Hyperactivity; Brain Ischemia; Ch | 2009 |
Neuroprotective effects vary across nonsteroidal antiinflammatory drugs in a mouse model of developing excitotoxic brain injury.
Topics: Acetaminophen; Adrenal Cortex Hormones; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Ste | 2010 |
Aspirin protects dopaminergic neurons against lipopolysaccharide-induced neurotoxicity in primary midbrain cultures.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Astrocytes; Coculture Techniques; Dopamin | 2012 |
Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Anti-Infl | 2012 |
Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease.
Topics: Age of Onset; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antiparkinson Agents | 2007 |
Development of encephalopathic features similar to Reye syndrome in rabbits.
Topics: Acetaminophen; Animals; Aspirin; Disease Models, Animal; Encephalitis; Fatty Acids, Nonesterified; F | 1984 |