Compounds > aspirin
Page last updated: 2024-10-23

aspirin and Edema

aspirin has been researched along with Edema in 348 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"Thirty patients with osteoarthritis of knees or hips took part in a double-blind randomized 12-week inter-group clinical trial of diflunisal 250 mg to 375 mg twice daily against aspirin 500 mg to 750 mg four times daily using the double-placebo technique."9.04A clinical trial of diflunisal against aspirin in osteoarthritis. ( Grayson, MF, 1978)
" To evaluate the analgesic effects of AC, 4 different pain models including hot plate assay, acetic acid writhing assay, formalin and CFA induced pain models were adopted in this study."8.02Comparison of analgesic activities of aconitine in different mice pain models. ( Chen, J; Deng, J; Feng, Q; Han, J; Huang, Q; Leung, EL; Liu, Z; Lu, L; Qi, X; Wang, D; Wang, Y; Zhang, Y, 2021)
"01) decreased the paw oedema volume and granuloma dry weight as compared to control and it was comparable to that of aspirin and histopathological sections showed a decrease in granulation tissue formation as compared to control."7.88Effect of anti-inflammatory activity of ranolazine in rat model of inflammation. ( Davangeri, R; Hashilkar, NK; Majagi, SI; Naveena, R, 2018)
"According to the GA2LEN recommendations, nasal challenge test with lysine-aspirin should be performed only in patients with severe asthma, because the sensitivity of this test has been lower than in bronchial and oral challenge tests."7.76Evaluation of nasal mucosal swelling and microcirculation throughout nasal and bronchial provocation tests with lysine-aspirin in asthmatics with nasal polyposis. ( Dahlén, B; Ehnhage, A; Juto, JE; Kölbeck, KG; Stjärne, P, 2010)
" However, the role of LXA4 and aspirin (ASA)-triggered lipoxins (ATLs) in inflammatory edema formation remains unclear."7.73Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin. ( Calixto, JB; Henriques, Md; Kassuya, CA; Menezes-de-Lima, O; Nascimento, AF, 2006)
"Aspirin, when compared to placebo and controls, significantly increased muscle interstitial oedema when given orally and intravenously."7.69Aspirin increases tissue oedema after skeletal muscle ischaemia and reperfusion. ( Braithwaite, BD; Earnshaw, JJ; Gelabert, H; Moore, WS; Petrik, PV; Pollen, DN; Quinones-Baldrich, WJ, 1996)
"The relative potencies of PGD2, PGE2 and PGI2 in potentiating bradykinin-induced hyperalgesia and oedema were determined in the paws of aspirin-treated guinea-pigs."7.68Prostaglandin (PG) modulation of bradykinin-induced hyperalgesia and oedema in the guinea-pig paw--effects of PGD2, PGE2 and PGI2. ( Coleman, RA; Head, SA; Poll, CT; Whelan, CJ, 1991)
"The effect of combination NSAID therapy of tilomisole with aspirin or naproxen was studied in rats with carrageenan-induced paw edema and established adjuvant arthritis."7.68Interaction studies of tilomisole, aspirin, and naproxen in acute and chronic inflammation with assessment of gastrointestinal irritancy in the rat. ( Calhoun, W; Carlson, RP; Copenhaver, TW; Datko, LJ; Gilman, SC, 1992)
"The cyclooxygenase inhibitors indomethacin, piroxicam, ibuprofen, naproxen and flurbiprofen failed to block rat paw oedema induced by PAF-acether, whereas aspirin and sodium salicylate were effective."7.67Salicylates inhibit PAF-acether-induced rat paw oedema when cyclooxygenase inhibitors are ineffective. ( Cordeiro, RS; Martins, MA; Silva, PM; Vargaftig, BB, 1986)
"The antiphlogistic activity of meseclazone and its major metabolite, 5-chlorosalicylic acid, have been directly compared to acetylsalicylic acid, phenylbutazone, indomethacin and hydrocortisone in rat paw edema induced by eleven different phlogistic agents."7.66Comparative antiphlogistic activity of meseclazone, 5-chlorosalicylic acid, acetylsalicylic acid, phenylbutazone, indomethacin and hydrocortisone in various rat paw edema models. ( Sofia, RD, 1978)
"Choline was described to potentiate the antinociceptive action of aspirin at small doses in several inflammatory pain models."5.40Synergistic interaction between choline and aspirin against acute inflammation induced by carrageenan and lipopolysaccharide. ( Pan, ZY; Wang, H, 2014)
"Color vision function was measured at baseline in 2,701 patients enrolled in the Early Treatment Diabetic Retinopathy Study, a randomized trial investigating photocoagulation and aspirin in the treatment of diabetic retinopathy."5.09Impaired color vision associated with diabetic retinopathy: Early Treatment Diabetic Retinopathy Study Report No. 15. ( Barton, FB; Bresnick, GH; Fong, DS, 1999)
"Thirty patients with osteoarthritis of knees or hips took part in a double-blind randomized 12-week inter-group clinical trial of diflunisal 250 mg to 375 mg twice daily against aspirin 500 mg to 750 mg four times daily using the double-placebo technique."5.04A clinical trial of diflunisal against aspirin in osteoarthritis. ( Grayson, MF, 1978)
"The results of the VIGOR study that demonstrated an increase in risk of myocardial infarction with rofecoxib, can probably be explained by an anti-thrombotic effect of naproxene, the high dose of rofecoxib used, the type of patients included or the fact that aspirin had been contraindicated."4.82[Renal and cardiovascular effects of non-steroidal anti-inflammatories and selective cox 2 inhibitors]. ( Deray, G, 2004)
" To evaluate the analgesic effects of AC, 4 different pain models including hot plate assay, acetic acid writhing assay, formalin and CFA induced pain models were adopted in this study."4.02Comparison of analgesic activities of aconitine in different mice pain models. ( Chen, J; Deng, J; Feng, Q; Han, J; Huang, Q; Leung, EL; Liu, Z; Lu, L; Qi, X; Wang, D; Wang, Y; Zhang, Y, 2021)
" subterranea (EEVS) was investigated for its gastroprotective effects on aspirin plus pylorus ligation-induced gastric ulcerated rats using an in vivo assay."3.88Protective roles of Vigna subterranea (Bambara nut) in rats with aspirin-induced gastric mucosal injury. ( Balogun, ME; Besong, EE; Djobissie, FSA; Mbamalu, OS; Obimma, JN, 2018)
"01) decreased the paw oedema volume and granuloma dry weight as compared to control and it was comparable to that of aspirin and histopathological sections showed a decrease in granulation tissue formation as compared to control."3.88Effect of anti-inflammatory activity of ranolazine in rat model of inflammation. ( Davangeri, R; Hashilkar, NK; Majagi, SI; Naveena, R, 2018)
" In this study, taking advantage of the transparency of larval zebrafish, Danio rerio, we assessed cardiovascular toxicity of seven known human cardiotoxic drugs (aspirin, clomipramine hydrochloride, cyclophosphamide, nimodipine, quinidine, terfenadine and verapamil hydrochloride) and two non-cardiovascular toxicity drugs (gentamicin sulphate and tetracycline hydrochloride) in zebrafish using six specific phenotypic endpoints: heart rate, heart rhythm, pericardial edema, circulation, hemorrhage and thrombosis."3.80Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish. ( Dong, QX; Gao, JM; He, JH; Huang, CJ; Li, CQ; Xu, YQ; Xuan, YX; Yu, HP; Zhu, JJ, 2014)
" In addition, seven of newly synthesized compounds significantly inhibit xylene-induced ear edema and exhibit comparable or better anti-inflammatory activities than those of diosgenin and aspirin."3.78Synthesis, characterization and biological studies of diosgenyl analogues. ( Du, D; He, Y; Huang, B; Huang, W; Wu, X; Xing, Z; Zhang, R, 2012)
" The anti-inflammatory effect of the CH and HE extracts of the stem bark of Calotropis procera against carrageenan-induced paw oedema and also its gastromucosal protective effect has been studied by using two acute models: aspirin (100 mg/kg, p."3.77Anti-inflammatory and gastromucosal protective effects of Calotropis procera (Asclepiadaceae) stem bark. ( Talele, G; Tour, N, 2011)
" Due to the structural resemblance of DBM to the anti-inflammatory curcumin and an aspirin-like skeleton of DBM derivatives, we tested the anti-inflammatory effects of DBM and its derivatives, 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced tumor promotion as well as TPA- and arachidonic acid-induced mouse ear edema in skin of CD-1 mice."3.77Inhibitory effects of 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, β-diketone structural analogues of curcumin, on chemical-induced tumor promotion and inflammation in mouse skin. ( Ho, CT; Huang, MT; Lin, CC; Liu, Y, 2011)
" Derivatives 4a, 4b and 4c exhibited moderate to good anti-inflammatory and analgesic activity in carrageenan-induced rat paw edema and acetic acid-induced writhing in mice, respectively, with low ulcerogenicity compared with the standard drug indomethacin."3.76Synthesis and pharmacological evaluation of novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives as anti-inflammatory and analgesic agents. ( Gaba, M; Gaba, P; Sharma, V; Singh, D; Singh, S, 2010)
"The present study was undertaken to assess the activity/anti-inflammatory potential of Linum usitatissimum fixed oil against castor oil-induced diarrhoea, turpentine oil-induced joint oedema, formaldehyde and Complete Freund's Adjuvant (CFA)-induced arthritis in Wistar albino rats."3.76Therapeutic effect of Linum usitatissimum (flaxseed/linseed) fixed oil on acute and chronic arthritic models in albino rats. ( Kaithwas, G; Majumdar, DK, 2010)
"According to the GA2LEN recommendations, nasal challenge test with lysine-aspirin should be performed only in patients with severe asthma, because the sensitivity of this test has been lower than in bronchial and oral challenge tests."3.76Evaluation of nasal mucosal swelling and microcirculation throughout nasal and bronchial provocation tests with lysine-aspirin in asthmatics with nasal polyposis. ( Dahlén, B; Ehnhage, A; Juto, JE; Kölbeck, KG; Stjärne, P, 2010)
" Among the 12 prepared compounds, Compounds 3d, e, i and j exhibited significant anti-inflammatory activity in model of acute inflammation such as carrageenan-induced rat edema paw while compounds 3d and e showed considerable activity in model of chronic inflammation such as adjuvant-induced arthritis and were compared with diclofenac (13."3.75Synthesis and pharmacological evaluation of a novel series of 5-(substituted)aryl-3-(3-coumarinyl)-1-phenyl-2-pyrazolines as novel anti-inflammatory and analgesic agents. ( Aragade, P; Khode, S; Maddi, V; Mamledesai, S; Palkar, M; Ronad, PK; Satyanarayana, D; Thippeswamy, AH, 2009)
"6% of 10 ml) induced pain and the effects were also compared to aspirin, morphine and naloxone while formalin induced pain (0."3.75Antinociceptive activity of Amaranthus spinosus in experimental animals. ( Amresh, G; Rao, CV; Singh, S; Zeashan, H, 2009)
" The analgesic activity of the test compounds was determined by phenylbenzoquinone-induced writhing assay and the anti-inflammatory activity was evaluated by the carrageenan-induced rat paw edema model."3.75Synthesis and analgesic and anti-inflammatory activity of 6-phenyl/(4-methylphenyl)-3(2H)-pyridazinon-2-propionamide derivatives. ( Colak, MS; Gökçe, M; Küpeli, E; Sahin, MF, 2009)
"Substituted thiazoles with different structural features were synthesized and screened for their anti-inflammatory activity in acute carrageenin induced rat paw edema model and chronic formalin induced rat paw edema model."3.742-Amino-5-thiazolyl motif: a novel scaffold for designing anti-inflammatory agents of diverse structures. ( Franklin, PX; Nivsarkar, M; Padh, H; Pillai, AD; Rathod, PD; Sudarsanam, V; Vasu, KK; Yerande, S, 2008)
" Twenty-four of newly synthesized compounds significantly inhibited xylene-induced rat ear edema and exhibited comparable or better anti-inflammatory activities than the reference drug aspirin."3.74Toward the development of chemoprevention agents. Part II: Chemo-enzymatic synthesis and anti-inflammatory activities of a new class of 5-amino-2-substitutedphenyl-1,3-dioxacycloalkanes. ( Bi, L; Gu, K; Ju, J; Peng, S; Wang, C; Zhao, M, 2007)
" The products showed anti-inflammatory activities similar to aspirin when tested in the carrageenan-induced paw edema assay in the rat."3.74Searching for new NO-donor aspirin-like molecules: a new class of nitrooxy-acyl derivatives of salicylic acid. ( Biondi, S; Cena, C; Coruzzi, G; Donnola, M; Fruttero, R; Gasco, A; Guaita, E; Lazzarato, L; Marini, E; Morini, G; Ongini, E; Rolando, B, 2008)
" For the anti-inflammatory activity assessment, carrageenan-induced hind paw edema, PGE(2)-induced hind paw edema and 12-O-tetradecanoyl-13-acetate (TPA)-induced mouse ear edema models and for the antinociceptive activity, p-benzoquinone-induced abdominal constriction test were used."3.74Assessment of anti-inflammatory and antinociceptive activities of Daphne pontica L. (Thymelaeaceae). ( Kupeli, E; Tosun, A; Yesilada, E, 2007)
" Model one was based on observed potent inhibitory activity against carrageenan-induced hind paw oedema and the second model used was acetic acid-induced, increased vascular permeability model."3.74Flavonoids with anti-inflammatory and antinociceptive activity from Cistus laurifolius L. leaves through bioassay-guided procedures. ( Küpeli, E; Yesilada, E, 2007)
" The anti-inflammatory activities of these compounds were tested using the xylene-induced mouse ear edema model, from which multiple compounds possessing anti-inflammatory properties which surpass aspirin were identified; these compounds were then compared to establish structure-activity relationships."3.73Stereoselective synthesis and anti-inflammatory activities of 6- and 7-membered dioxacycloalkanes. ( Bi, L; Dolan, C; Gu, K; Kao, MC; Peng, S; Tok, JB; Wang, C; Zhao, M, 2006)
" However, the role of LXA4 and aspirin (ASA)-triggered lipoxins (ATLs) in inflammatory edema formation remains unclear."3.73Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin. ( Calixto, JB; Henriques, Md; Kassuya, CA; Menezes-de-Lima, O; Nascimento, AF, 2006)
"In this study, amide derivatives of [6-(5-methyl-3-phenyl-pyrazole-1-yl)-3(2H)-pyridazinone-2-yl]acetic acid were synthesized and tested for their in vivo analgesic and anti-inflammatory activity by using the p-benzoquinone-induced writhing test and carrageenan-induced hind paw edema model, respectively."3.72Amide derivatives of [6-(5-methyl-3-phenylpyrazole-1-yl)-3(2H)-pyridazinone-2-yl]acetic acids as potential analgesic and anti-inflammatory compounds. ( Akoğlu, C; Banoglu, E; Küpeli, E; Sahin, MF; Unlü, S; Yeşilada, E, 2004)
"In conscious rats celecoxib, indomethacin and acetylsalicylic acid significantly reduced the paw oedema induced by carrageenan."3.72Gastric effects of the selective cyclooxygenase-2 inhibitor, celecoxib, in the rat. ( Coppelli, G; Coruzzi, G; Guaita, E; Spaggiari, S, 2004)
" Furthermore bukittinggine could significantly reduce fever in yeast-induced hyperthermic rats and possessed analgesic activity comparable to that of acetylsalicylic acid when tested in acetic acid-induced writhing response in mice."3.70Anti-inflammatory activity of the alkaloid bukittinggine from Sapium baccatum. ( Arbain, D; Kanjanapothi, D; Panthong, A; Taesotikul, T; Thitiponpunt, Y, 1998)
" Eleven compounds in series I plus one in series II and six in series I plus seven in series II were active in the carrageenan-induced edema and acetic acid-induced writhing assays, respectively."3.69Synthesis and antiinflammatory, analgesic, and antipyretic testing of 4-[1-oxo-(3-substituted aryl)-2-propenyl]-3-phenylsydnones and of 3-[4-[3-(substituted aryl)-1-oxo-2-propenyl]phenyl]sydnones. ( Rao, MN; Satyanarayana, K, 1995)
" Since the non-steroidal anti-inflammatory agents, indomethacin and aspirin, were inactive, cyclooxygenase products are not involved in the anaphylactic reaction in boosted or unboosted mice."3.69Involvement of leukotrienes in allergic inflammation in mice. ( Cordeiro, RS; Vargaftig, BB; Zuany-Amorim, C, 1994)
"Aspirin, when compared to placebo and controls, significantly increased muscle interstitial oedema when given orally and intravenously."3.69Aspirin increases tissue oedema after skeletal muscle ischaemia and reperfusion. ( Braithwaite, BD; Earnshaw, JJ; Gelabert, H; Moore, WS; Petrik, PV; Pollen, DN; Quinones-Baldrich, WJ, 1996)
" Pulmonary thromboembolism-induced Evans blue dye leakage was also reduced significantly by aspirin (5 mg/kg), but PGE1 (170 micrograms/kg) showed a tendency to potentiate the edematogenic response."3.69Anti-inflammatory effects of beraprost sodium, a stable analogue of PGI2, and its mechanisms. ( Annoh, S; Koike, H; Nishio, S; Ueno, Y, 1997)
"The relative potencies of PGD2, PGE2 and PGI2 in potentiating bradykinin-induced hyperalgesia and oedema were determined in the paws of aspirin-treated guinea-pigs."3.68Prostaglandin (PG) modulation of bradykinin-induced hyperalgesia and oedema in the guinea-pig paw--effects of PGD2, PGE2 and PGI2. ( Coleman, RA; Head, SA; Poll, CT; Whelan, CJ, 1991)
"Low-dose Aspirin inhibits thromboxane A2 with minimal effects on prostacyclin and induces clinical improvements in pre-eclampsia."3.68Treatment of severe pre-eclampsia by acetyl salicylic acid. ( Abd-Rabbo, S; Khowessah, M; Shaala, S; Toppozada, M; Zoheir, A, 1991)
" The edematogenic reaction appeared 5 min after the intraplantar injection of ovalbumin, peaked at 30 min after the antigenic challenge, and decreased thereafter."3.68Effect of PAF-acether antagonists on active anaphylactic mouse paw edema. ( Amorim, CZ; Cordeiro, RS; Henriques, MG; Vargaftig, BB; Weg, VB, 1991)
"The effect of combination NSAID therapy of tilomisole with aspirin or naproxen was studied in rats with carrageenan-induced paw edema and established adjuvant arthritis."3.68Interaction studies of tilomisole, aspirin, and naproxen in acute and chronic inflammation with assessment of gastrointestinal irritancy in the rat. ( Calhoun, W; Carlson, RP; Copenhaver, TW; Datko, LJ; Gilman, SC, 1992)
") administered arachidonic acid, the PG precursor, produced a statistically insignificant increase in the inflammatory response, though PG synthesis inhibitors, administered by the same route, markedly attenuated the oedema."3.67Effect of central prostaglandins on carrageenan-induced pedal oedema in rats. ( Bhattacharya, SK; Das, N, 1984)
"Dipyrone blocked carrageenin-induced oedema and hyperalgesia in a dose-dependent manner."3.67Mode of analgesic action of dipyrone: direct antagonism of inflammatory hyperalgesia. ( Ferreira, SH; Lorenzetti, BB, 1985)
"Sequential potentiation of antiinflammatory activity of dexamethasone was obtained by co-administration of diclofenac-Na (and indomethacin), but not of phenylbutazone and, apparently, of acetylsalicylic acid (ASA) in the carrageenin rat paw edema."3.67On steroid-saving drug combinations in carrageenin paw edema and adjuvant arthritis. ( Bekemeier, H; Hirschelmann, R, 1986)
"The cyclooxygenase inhibitors indomethacin, piroxicam, ibuprofen, naproxen and flurbiprofen failed to block rat paw oedema induced by PAF-acether, whereas aspirin and sodium salicylate were effective."3.67Salicylates inhibit PAF-acether-induced rat paw oedema when cyclooxygenase inhibitors are ineffective. ( Cordeiro, RS; Martins, MA; Silva, PM; Vargaftig, BB, 1986)
" The anti-inflammatory properties of FPP028 were evaluated through the carrageenan induced paw edema and the cotton pellet induced granuloma and compared with the activity of indomethacin, phenylbutazone, and isoxicam; as a result, the activity of FPP028 was shown to be similar to that of the latter compounds."3.67Pharmacological activity of FPP028 (2-phenylpyrazolo-4-ethyl-4,7-dihydro [1,5a]pyrimidin-7-one) a new non-steroid anti-inflammatory agent. ( Banchelli, G; Bianchini, F; Ignesti, G; Pecori-Vettori, L; Pirisino, R; Rafanelli, D; Raimondi, L, 1986)
"On the ground of conflicting evidence concerning the interaction of salicylate and aspirin, we investigated the results of such interaction on carrageenin edema of the rat hind paw."3.67Salicylate antagonizes the antiinflammatory action of aspirin in the rat. ( Danon, A; Telias, ID; Zvi, ZB, 1985)
" In carrageenin-induced oedema indoprofen and prednisolone had a synergistic anti-inflammatory effect, and indoprofen and acetylsalicylic acid showed an additive effect."3.66Preclinical studies on indoprofen, a new non-steroidal analgesic-antiinflammatory agent. ( Buttinoni, A; Tommasini, R, 1981)
" Injected in the paw of the rat, polymorphonuclear leucocytes do not increase the oedematogen action of bradykinin, but increase the action of lambda carrageenan."3.66[Interaction of polymorphonuclear leukocytes, bradykinin and carragenin. Transference reaction in the rat]. ( Damas, J; Lismonde, M; Remacle-Volon, G, 1982)
"The effects of aspirin, salicylic acid and gentisic acid on the paw swellings in the arachidonic acid-potentiated and in the conventional carrageenan-induced oedema tests as well as on the content of prostaglandin-like activity and leucocyte migration in the exudate of inert implanted sponges in the rat have been studied."3.66Aspirin, salicylate and prostaglandins. ( Ford-Hutchinson, AW; Slack, JA; Smith, MJ; Walker, JR, 1979)
"Effects of ketoprofen, indomethacin, phenylbutazone and acetylsalicylic acid on edema and on in vivo and in vitro synthesis of PGE1, PGE2 and PGF2 alpha in response to carrageenin were studied in rats."3.66Studies on the effects of anti-inflammatory action of benzoyl-hydrotropic acid (ketoprofen) and other drugs, with special reference to prostaglandin synthesis. ( Kawamoto, H; Komatsu, H; Kubota, T; Yamada, T, 1979)
"The antiphlogistic activity of meseclazone and its major metabolite, 5-chlorosalicylic acid, have been directly compared to acetylsalicylic acid, phenylbutazone, indomethacin and hydrocortisone in rat paw edema induced by eleven different phlogistic agents."3.66Comparative antiphlogistic activity of meseclazone, 5-chlorosalicylic acid, acetylsalicylic acid, phenylbutazone, indomethacin and hydrocortisone in various rat paw edema models. ( Sofia, RD, 1978)
" None of the newly reported compounds exhibited activity equal to that of aspirin in the carrageenin-induced rat foot edema assay."3.65Synthesis and antiinflammatory properties of N-substituted 4,5-dioxopyrrolidine-3-carboxanilides. ( Kadin, SB, 1976)
" In a rat paw edema test for anti-inflammatory activity naproxen was 55 times more active than aspirin."3.65Chemistry and pharmacology of naproxen. ( Dorfman, RI, 1975)
"2-Carboxyaryl-substituted dihydrobenz[e]indoles, tetrahydroindoles, and tetrahydrobenzofurans have been synthesized as structural analogues of fendosal, a new antiinflammatory agent, and tested in the carrageenan-induced rat paw edema assay."3.65Synthesis of carboxyarylindoles and benzofurans as nonsteroidal antiinflammatory agents. ( Effland, RC, 1977)
"Nabumetone is an appropriate choice of nonsteroidal anti-inflammatory drug for the treatment of sports injury."2.66Nabumetone in the treatment of skin and soft tissue injury. ( Jenner, PN, 1987)
"In a double-blind crossover study acetylsalicylic acid (ASA) in low (2 g daily) or high (4 g daily) dosage was tested against placebo in two groups of 20 patients who each underwent identical oral surgical procedures on two separate occasions."2.65The effects of acetylsalicylic acid on swelling, pain and other events after surgery. ( Skjelbred, P, 1984)
"Kawasaki disease is an acute systemic vasculitis of childhood."2.50Retropharyngeal involvement in Kawasaki disease--a report of four patients with retropharyngeal edema verified by magnetic resonance imaging. ( Kajosaari, L; Klockars, T; Nieminen, T; Puhakka, L; Saat, R; Salo, E, 2014)
"This is a report on two cases of Kawasaki disease showing facial palsy with indurative oedema during their clinical course, and also a clinical review of the ten previously reported cases of facial palsy complicating Kawasaki disease."2.37Facial palsy in Kawasaki disease. Report of two cases and a review. ( Fukushige, J; Hattori, T; Nanri, T; Tasaki, H; Tokugawa, K; Ueda, K, 1987)
"Aspirin-like drugs inhibit the biosynthesis of prostaglandins in all tissues and species so far studied."2.35The mode of action of aspirin and similar compounds. ( Vane, JR, 1976)
"No thrombosis was detected."1.48Long-haul flights, edema, and thrombotic events: prevention with stockings and Pycnogenol® supplementation (LONFLIT Registry Study). ( Belcaro, G; Cornelli, U; Cotellese, R; Dugall, M; Feragalli, B; Hosoi, M, 2018)
"Aspirin 100 mg/kg was used as a positive control."1.48Methanolic Extract of Leathery Murdah, Terminalia coriacea (Roxb.) Wight and Arn. Leaves Exhibits Anti-Inflammatory Activity in Acute and Chronic Models. ( Al-Sanea, MM; Gamal Mahmoud, M; Khatoon, N; Rahman, HU; Safwan Ali Khan, M, 2018)
"extract is traditionally used for the treatment of inflammation, bronchopneumonia, feverish pains, and breast cancer."1.48The new plant Parinari kerstingii Engl.: Toxicity studies and anti-inflammatory properties. ( Alolga, RN; Hanson, C; Linus, LO; Liu, Q; Lu, YT; Njokuocha, RC; Qi, LW; Shi, N; Wang, SL, 2018)
"The patient was treated for presumptive peritonsillar abscess."1.48Acute peritonsillar swelling: a unique presentation for Kawasaki disease in adolescence. ( Connell, JT; Park, JH, 2018)
"Immunological TRALI was tested in mice exhibiting severe thrombocytopenia or platelet dysfunction."1.43Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse. ( de la Salle, H; El Mdawar, MB; Gachet, C; Hechler, B; Heim, V; Magnenat, S; Maître, B, 2016)
"We report a 3-year-old girl with Kawasaki disease who presented with retropharyngeal edema and shock syndrome."1.40Unusual manifestations of Kawasaki disease with retropharyngeal edema and shock syndrome in a Taiwanese child. ( Chen, CK; Chu, SH; Fang, LC; Jim, WT; Kao, YH; Liu, LC; Peng, CC; Shyur, SD, 2014)
"Choline was described to potentiate the antinociceptive action of aspirin at small doses in several inflammatory pain models."1.40Synergistic interaction between choline and aspirin against acute inflammation induced by carrageenan and lipopolysaccharide. ( Pan, ZY; Wang, H, 2014)
" The serial dosages were used in vivo: the low dosage, the medium dosage and the high dosage."1.39Anti-inflammatory effects of essential oil in Echinacea purpurea L. ( Hu, F; Jiang, L; Tai, Y; Xie, Z; Yang, X; Yu, D; Yuan, Y, 2013)
"The inflammation is one of the initial parameter for most of the disorders occurring in the body."1.37Differential inhibitory potencies of alcoholic extract of different parts of Dryopteris chrysocoma on inflammation in mice and rats. ( Ahmad, M; Jahan, N; Mohammad, N; Rehman, AB; Ullah, O, 2011)
"To discover analgesics for treating chronic pain 17 novel Schiff's bases, N,N'-(Z-allylidene-1,3-diyl)bisamino acid methyl esters were prepared from 1,1,3,3,-tetramethoxypropane and amino acid methyl esters."1.36A class of novel Schiff's bases: Synthesis, therapeutic action for chronic pain, anti-inflammation and 3D QSAR analysis. ( Li, C; Peng, L; Peng, S; Wu, J; Wu, Y; Zhao, M; Zheng, M; Zhou, Y, 2010)
"The aspirin prodrug ( 23) was a 2."1.35Second-generation aspirin and indomethacin prodrugs possessing an O(2)-(acetoxymethyl)-1-(2-carboxypyrrolidin-1-yl)diazenium-1,2-diolate nitric oxide donor moiety: design, synthesis, biological evaluation, and nitric oxide release studies. ( Chen, QH; Citro, ML; Keefer, LK; Knaus, EE; Velázquez, CA, 2008)
"Acute inflammation was induced by subplantar injection of 0."1.33New xanthone derivatives as potent anti-inflammatory agents. ( Czarnecki, R; Czekaj, T; Librowski, T; Marona, H, 2005)
"Decompression sickness is an uncommon but serious risk associated with flying and SCUBA diving with potential for significant morbidity and mortality."1.31Cases from the aerospace medicine residents' teaching file. Decompression sickness. ( Taylor, GN, 2000)
" The results of the pharmacokinetic analyses from blood and urinary data indicated no significant differences in the disposition of ASA between CuD and CuS rats."1.29Pharmacokinetics and pharmacodynamics in copper deficiency. I. Antiinflammatory activity of aspirin. ( Bacolod, M; Dawson, C; Gonzales, C; Kishore, V; Lopez-Anaya, A, 1994)
"The steroids in vernal keratoconjunctivitis (VKC) are not always effective and may result in glaucoma."1.28Evaluation of combined systemic aspirin and cromolyn sodium in intractable vernal catarrh. ( Chaudhary, KP, 1990)
"Pretreatment with diphenhydramine or methysergide significantly reduced trimucase-induced paw swelling, while aspirin had no effect."1.28Comparison of kinin-forming and amidolytic activities of four trimucases, oedema-producing and kinin-releasing enzymes, from Trimeresurus mucrosquamatus venom. ( Hsu, MF; Teng, CM; Wang, JP, 1992)
"aspirin were additive."1.27Therapeutic and adjunctive applications of an imidazoline anti-inflammatory agent. ( Holsapple, MP; Nichols, DE; Trizzino, J; Yim, GK, 1983)
"025-16 micrograms/paw) were followed by a bell-shaped dose-response curve for oedema."1.27Interactions between local inflammatory and systemic haematological effects of PAF-acether in the rat. ( Castro, HC; Cordeiro, RS; Lima, MC; Martins, MA; Neto, F; Silva, PM; Vargaftig, BB, 1987)
"4."1.26Blockade of the inflammatory effects of platelet-activating factor by cyclo-oxygenase inhibitors. ( Ferreira, SH; Vargaftig, BB, 1981)
" These results suggest that Y-8004 may make feasible a reduction in dosage or a withdrawal of the steroid prescription."1.26[Pharmacological studies of 2-(5H-(1)benzopyrano[2,3-b]pyridin-7-yl)propionic acid (Y-8004). (3) Its interaction with anti-inflammatory agents]. ( Foto, K; Imayoshi, T; Kadobe, Y; Maruyama, Y, 1977)
" This dosage of aspirin does not affect the hypotensive activity of arachidonic acid nor the oedematous properties of carrageenan in the rat."1.26[Role of platelets in arterial hypotension induced by arachidonic acid and in carrageenan induced edema in the rat]. ( Damas, J; Volon, G, 1979)
"Butibufen was within the potency range of ibuprofen as an antipyretic and analgesic agent and greater than that of acetylsalicylic acid."1.26Some aspects of the pharmacology of butibufen, a non-steroidal anti-inflammatory agent. ( Aparicio, L, 1977)
" The very shallow dose-response curves for flurbiprofen compared with acetylsalicylic acid, especially in the mouse and the rat test systems, are not due to an unreliable or abnormal absorption, which suggests that in these species the mode of action of flurbiprofen is not identical with that of acetylsalicylic acid."1.25Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent. ( Adams, SS; McCullough, KF; Nicholson, JS, 1975)
" Phenylbutazone, aspirin and indomethacin were all well absorbed after oral administration, and the resultant plasma drug concentrations were closely similar to those produced when the drugs were administered intraperitoneally."1.25Factors influencing the inhibitory action of anti-inflammatory drugs on carrageenin induced oedema. ( Green, AY; Green, D; Murray, PA; Wilson, AB, 1971)

Research

Studies (348)

TimeframeStudies, this research(%)All Research%
pre-1990172 (49.43)18.7374
1990's37 (10.63)18.2507
2000's66 (18.97)29.6817
2010's66 (18.97)24.3611
2020's7 (2.01)2.80

Authors

AuthorsStudies
Clark, RL1
Pessolano, AA1
Witzel, B1
Lanza, T1
Shen, TY2
Van Arman, CG1
Risley, EA2
Jones, H1
Fordice, MW1
Greenwald, RB1
Hannah, J1
Jacobs, A1
Ruyle, WV1
Walford, GL1
Paris, GY3
Garmaise, DL2
Cimon, DG2
Swett, L2
Carter, GW4
Young, P2
Effland, RC1
O'Rourke, M1
Lang, SA1
cohen, E1
Brannigan, LH1
Hodge, RB1
Field, L1
Kadin, SB1
Anderson, VB1
Agnew, MN1
Allen, RC1
Wilker, JC1
Lassman, HB1
Novick, WJ1
Safak, C2
Erdogan, H2
Palaska, E2
Sunal, R1
Duru, S2
Muchowski, JM1
Galeazzi, E1
Greenhouse, R1
Guzmán, A1
Peréz, V1
Ackerman, N1
Ballaron, SA1
Rovito, JR1
Tomolonis, AJ2
Young, JM1
Lazer, ES1
Matteo, MR1
Possanza, GJ1
Toja, E1
Selva, D4
Schiatti, P4
Bruno, O2
Brullo, C2
Ranise, A1
Schenone, S1
Bondavalli, F1
Barocelli, E3
Ballabeni, V3
Chiavarini, M1
Tognolini, M2
Impicciatore, M1
Lolli, ML3
Cena, C4
Medana, C1
Lazzarato, L5
Morini, G5
Coruzzi, G5
Manarini, S1
Fruttero, R5
Gasco, A5
Rao, PN1
Chen, QH2
Knaus, EE7
Zheng, X1
Oda, H1
Takamatsu, K1
Sugimoto, Y1
Tai, A1
Akaho, E1
Ali, HI1
Oshiki, T1
Kakuta, H1
Sasaki, K1
Venu, TD2
Shashikanth, S2
Khanum, SA3
Naveen, S1
Firdouse, A2
Sridhar, MA1
Shashidhara Prasad, J1
Franklin, PX1
Pillai, AD1
Rathod, PD1
Yerande, S1
Nivsarkar, M1
Padh, H1
Vasu, KK1
Sudarsanam, V1
Gu, K3
Bi, L6
Zhao, M4
Wang, C3
Ju, J2
Peng, S4
Salgin-Gökşen, U1
Gökhan-Kelekçi, N2
Göktaş, O2
Köysal, Y1
Kiliç, E1
Işik, S1
Aktay, G2
Ozalp, M1
Yabanoğlu, S1
Küpeli, E8
Salgin, U1
Ozgen, O1
Uçar, G1
Yeşilada, E6
Kendi, E1
Yeşilada, A1
Bilgin, AA1
Sharma, M1
Ray, SM2
Donnola, M2
Rolando, B3
Marini, E3
Guaita, E4
Biondi, S1
Ongini, E1
Velázquez, CA2
Citro, ML1
Keefer, LK2
Chowdhury, MA4
Chen, H1
Abdellatif, KR5
Dong, Y4
Petruk, KC1
Manuprasad, BK1
Mohamed, R1
Vishwanth, BS1
Khanum, NF1
Shashikanth, M1
Das, D2
Suresh, MR2
el-Gazzar, AB1
Hafez, HN1
Nawwar, GA1
Khode, S1
Maddi, V1
Aragade, P1
Palkar, M1
Ronad, PK1
Mamledesai, S1
Thippeswamy, AH1
Satyanarayana, D1
Jayashankar, B1
Lokanath Rai, KM1
Baskaran, N1
Sathish, HS1
Yu, G1
Velázquez, C2
Gökçe, M2
Utku, S1
Aytaç, SP1
Tozkoparan, B2
Kaynak, FB1
Unüvar, S1
Gaba, M1
Singh, D1
Singh, S2
Sharma, V1
Gaba, P1
Zhou, Y1
Wu, Y1
Li, C1
Wu, J1
Zheng, M1
Peng, L1
Khan, KM1
Ambreen, N1
Mughal, UR1
Jalil, S1
Perveen, S1
Choudhary, MI1
Bi, W3
Bi, Y3
Xue, P2
Zhang, Y4
Gao, X3
Wang, Z1
Li, M2
Baudy-Floc'h, M1
Ngerebara, N1
Li, X1
Gibson, KM2
Guglielmo, S1
Tan, CM1
Chen, GS1
Chen, CS1
Chang, PT1
Chern, JW1
Jain, S1
Tran, S1
El Gendy, MA1
Kashfi, K2
Jurasz, P1
Velázquez-Martínez, CA1
Rocca, M1
Fossa, P1
Cichero, E1
Flammini, L2
Giorgio, C2
Saccani, F1
Domenichini, G1
Zeng, L2
Zhang, J3
Huang, B1
Du, D1
Zhang, R1
Wu, X1
Xing, Z1
He, Y1
Huang, W1
Jadhav, SY1
Shirame, SP1
Kulkarni, SD1
Patil, SB1
Pasale, SK1
Bhosale, RB1
Haseena banu, B1
Prasad, KV1
Bharathi, K1
Palkar, MB1
Singhai, AS1
Ronad, PM1
Vishwanathswamy, AH1
Boreddy, TS1
Veerapur, VP1
Shaikh, MS1
Rane, RA1
Karpoormath, R1
Di Braccio, M1
Grossi, G1
Alfei, S1
Bertoni, S1
Xu, G1
Gao, P1
Zhang, M1
Li, H1
Yan, X2
Bammert, CE1
Legalley, TD2
Michael Gibson, K1
Wang, JX1
Harris, J1
Shchegol'kov, EV1
Shchur, IV1
Burgart, YV1
Saloutin, VI1
Trefilova, AN1
Ljushina, GA1
Solodnikov, SY1
Markova, LN1
Maslova, VV1
Krasnykh, OP1
Borisevich, SS1
Khursan, SL1
Li, J1
Li, D1
Xu, Y1
Guo, Z1
Liu, X1
Yang, H1
Wu, L2
Wang, L1
Jan, MS1
Ahmad, S1
Hussain, F1
Ahmad, A1
Mahmood, F2
Rashid, U1
Abid, OU1
Ullah, F1
Ayaz, M2
Sadiq, A1
Rahman, K1
Ali, G1
Khan, R1
Khan, I1
Ali, I1
Mosa, OF1
Ahmed, A1
Nawaz, A1
Murthy, HCA1
Zhang, N1
Liu, Z2
Luo, H1
Wu, W1
Nie, K1
Cai, L1
Tan, S1
Chen, X1
Huang, Y1
Liu, J1
Lv, M1
Zhang, X1
Fan, Y1
Lin, Y1
Ye, S1
Liu, Y2
Xu, J1
Orieke, D1
Ohaeri, OC1
Ijeh, II1
Ijioma, SN1
Yellamaty, V1
Steele, RW1
Lal, S1
Hashmi, J1
Gallerani, M1
Pala, M1
Fabbian, F1
De Giorgi, A1
Deng, J1
Han, J1
Chen, J1
Huang, Q1
Wang, Y1
Qi, X1
Leung, EL1
Wang, D1
Feng, Q1
Lu, L1
Sun, Q1
Yang, Y1
Poddighe, D1
Rahmani, MR1
Shamsizadeh, A1
Moghadam-Ahmadi, A1
Kaeidi, A1
Allahtavakoli, M1
Belcaro, G1
Cornelli, U1
Dugall, M1
Hosoi, M1
Cotellese, R1
Feragalli, B1
Safwan Ali Khan, M1
Khatoon, N1
Al-Sanea, MM1
Gamal Mahmoud, M1
Rahman, HU1
Linus, LO1
Wang, SL1
Shi, N1
Hanson, C1
Lu, YT1
Alolga, RN1
Liu, Q1
Njokuocha, RC1
Qi, LW1
Murashko, TO1
Simirnov, IV1
Bondarev, AA1
Ivanov, AA1
Postnikov, PS1
Nemtsev, AO1
Udut, VV1
DeFilippis, EM1
Tsao, AL1
Loscalzo, J1
Connell, JT1
Park, JH1
Balogun, ME1
Besong, EE1
Obimma, JN1
Mbamalu, OS1
Djobissie, FSA1
Naveena, R1
Hashilkar, NK1
Davangeri, R1
Majagi, SI1
Yonezawa, Y1
Kihara, T1
Ibi, K1
Senshu, M1
Nejishima, H1
Takeda, Y1
Imai, K1
Ogawa, H1
Yu, D1
Yuan, Y1
Jiang, L1
Tai, Y1
Yang, X1
Hu, F1
Xie, Z1
Kotake, D1
Hirasawa, N1
Jacob, JN2
Badyal, DK2
Bala, S2
Toloue, M1
Joseph, S1
Pozzoli, C1
Zuo, J1
Du, L1
Liu, B1
Zhu, W1
Jin, Y1
Pan, ZY1
Wang, H1
Puhakka, L1
Saat, R1
Klockars, T1
Kajosaari, L1
Salo, E1
Nieminen, T1
Raju, GS1
Moghal, MM1
Hossain, MS1
Hassan, MM1
Billah, MM1
Ahamed, SK1
Rana, SM1
Sauer, S1
Goltz, JP1
Gassenmaier, T1
Kunz, AS1
Bley, TA1
Klein, D1
Petritsch, B1
Taher, YA1
Samud, AM1
El-Taher, FE1
ben-Hussin, G1
Elmezogi, JS1
Al-Mehdawi, BF1
Salem, HA1
Wang, J1
Wang, JA1
Jiang, YX1
Zhou, PP1
Wang, HH1
Han, YM1
Woo, SU1
Choi, MS1
Park, YN1
Kim, SH1
Yim, H1
Yoo, HH1
Khan, SA1
Chatterjee, SS1
Kumar, V2
Hechler, B1
Maître, B1
Magnenat, S1
Heim, V1
El Mdawar, MB1
Gachet, C1
de la Salle, H1
Subramanian, B1
Kuo, F1
Ada, E1
Kotyla, T1
Wilson, T1
Yoganathan, S1
Nicolosi, R1
Zakaria, ZA1
Kumar, GH1
Mat Jais, AM1
Sulaiman, MR1
Somchit, MN1
Langley, EW1
Kirse, DK1
Barnes, CE1
Covitz, W1
Shetty, AK1
Alagarsamy, V3
Shankar, D2
Solomon, VR1
Sheorey, RV1
Parthiban, P2
Zeashan, H1
Amresh, G1
Rao, CV1
Colak, MS1
Sahin, MF2
Wait, SD1
Abla, AA1
Killory, BD1
Starke, RM1
Spetzler, RF1
Nakaji, P1
Kaithwas, G1
Majumdar, DK1
Ehnhage, A1
Kölbeck, KG1
Juto, JE1
Dahlén, B1
Stjärne, P1
Ghannoum, JE1
Odingo, NA1
Provost, N1
Chattopadhyay, M1
Pruski, A1
Nia, KV1
Conte, FP1
Menezes-de-Lima, O2
Verri, WA1
Cunha, FQ1
Penido, C1
Henriques, MG2
Chavan, MJ1
Wakte, PS1
Shinde, DB1
Tour, N1
Talele, G1
Khan, S1
Mehmood, MH1
Ali, AN1
Ahmed, FS1
Dar, A1
Gilani, AH1
Flores-Santana, W1
Moody, T1
Chen, W1
Gorczynski, MJ1
Shoman, ME1
Thetford, A1
Mitchell, JB1
Cherukuri, MK1
King, SB1
Wink, DA1
Lin, CC1
Ho, CT1
Huang, MT1
Chatter, R1
Othman, RB1
Rabhi, S1
Kladi, M1
Tarhouni, S1
Vagias, C1
Roussis, V1
Guizani-Tabbane, L1
Kharrat, R1
Ahmad, M2
Jahan, N1
Rehman, AB1
Ullah, O1
Mohammad, N1
Kaur, J1
Bhardwaj, A1
Huang, Z1
Batalova, TA1
Dorovskich, VA1
Kurochkina, GI1
Grachev, MK1
Plastinin, ML1
Sergievich, AA1
Fang, LC1
Shyur, SD1
Peng, CC1
Jim, WT1
Chu, SH1
Kao, YH1
Chen, CK1
Liu, LC1
Tang, SY1
Sivakumar, M1
Ng, AM1
Shridharan, P1
Besada, E1
Nossent, JC1
Zhu, JJ1
Xu, YQ1
He, JH1
Yu, HP1
Huang, CJ1
Gao, JM1
Dong, QX1
Xuan, YX1
Li, CQ1
McElroy, SP1
Megson, IL1
Adzu, B1
Amos, S1
Kapu, SD1
Gamaniel, KS1
Srivastava, RM1
de Almeida Lima, A1
Viana, OS1
da Costa Silva, MJ1
Catanho, MT1
de Morais, JO1
Ghate, M1
Manohar, D1
Kulkarni, V1
Shobha, R1
Kattimani, SY1
Jakubkiene, V1
Burbuliene, MM1
Mekuskiene, G1
Udrenaite, E3
Gaidelis, P2
Vainilavicius, P1
Unlü, S3
Baytas, SN1
Muniappan, M1
Sundararaj, T1
WAGNER-JAUREGG, T2
JAHN, U2
VOGIN, EE1
ROSSI, GV1
WINTER, CA1
NUSS, GW1
GILFOIL, TM1
KLAVINS, I1
GRUMBACH, L1
LISIN, N1
LECLERCQ, R1
BLANPIN, O1
ARRIGONI-MARTELLI, E4
CONTI, I1
CREPAX, P1
SILVESTRINI, B1
CHRISTENSSON, B1
GUSTAFSON, A1
WESTLING, H1
BRUUN, E1
BROWN, DM1
ROBSON, RD1
DELBARRE, F1
BUU-HOUI, NP1
JACQUIGNON, P1
BROUILHET, H1
KAHAN, A1
MARTY, M1
CARMINATI, GM1
Remes, V1
Helenius, I1
Kazemekaite, M1
Talaikyte, Z1
Labanauskas, L2
Staniulyte, Z1
Palaima, A1
Banoglu, E1
Akoğlu, C1
LA BELLE, A1
TORNABEN, JA1
Gökhan, N1
Ertan, M1
Deray, G1
Coppelli, G1
Spaggiari, S1
Karmakar, S1
Muhuri, DC1
Dasgupta, SC1
Nagchaudhuri, AK1
Gomes, A1
Vodegel, RM1
Kardaun, SH1
Librowski, T1
Czarnecki, R1
Czekaj, T1
Marona, H1
Yu, Y1
Cheng, Y1
Fan, J1
Chen, XS1
Klein-Szanto, A1
Fitzgerald, GA1
Funk, CD1
Dolan, C1
Kao, MC1
Tok, JB1
Abdel-Rahman, HM1
Hussein, MA1
Kassuya, CA1
Nascimento, AF1
Henriques, Md1
Calixto, JB2
Murugan, M1
Siddiqui, AA1
Rajesh, R1
Turchin, I1
Barankin, B1
Fuentes, V1
de Frutos, C1
de Barrio, M1
Barranco, R1
Herrero, T1
Tornero, P1
Zhang, B1
Li, JB1
Zhang, DM1
Ding, Y1
Du, GH1
Stillman, MJ1
Stillman, MT1
Dhanabal, K1
Anjana, G1
Deepa, G1
Murugesan, B1
Rajkumar, S1
Beevi, AJ1
Yuan, SH1
Wang, CX1
Li, JP1
Liang, ZM1
Yuan, Z1
Tosun, A1
Wilson, HD1
Toepfer, VE1
Senapati, AK1
Wilson, JR1
Fuchs, PN1
Jori, A1
Bernardi, D1
Glenn, EM2
Bowman, BJ1
Kooyers, W1
Koslowske, T1
Myers, ML1
Bekemeier, H3
Leuschner, G1
Schmollack, W2
Starr, MS1
West, GB1
Grupe, R1
Rösner, G1
Denk, J1
Göres, E1
Bhattacharya, SK2
Das, N1
Lismonde, M1
Damas, J2
Remacle-Volon, G1
Skjelbred, P1
Cantrill, HL1
Lisciani, R1
Fattorusso, E1
Surano, V1
Cozzolino, S1
Giannattasio, M1
Sorrentino, L1
Böhme, HR1
Schottke, C1
Thiel, J1
Lück, U1
van Kolfschoten, AA1
Hagelen, F1
van Noordwijk, J1
Vargaftig, BB5
Ferreira, SH3
Buttinoni, A1
Tommasini, R1
Holsapple, MP1
Trizzino, J1
Nichols, DE1
Yim, GK1
Young, PR3
Swett, LR1
Aonuma, S1
Kohama, Y1
Komiyama, Y1
Fujimoto, S1
García Rafanell, J1
Bellés, L1
Sánchez, MS1
Forn, J1
Bluth, R1
Rice, TA1
Fritz, ME1
Giambonini, S1
Jenni, R1
D'Apuzzo, V1
Tsurumi, K3
Kyuki, K1
Fujimura, H3
Sugishita, E1
Amagaya, S1
Ogihara, Y1
Tsurufuji, S1
Sugio, K1
Takemasa, F1
Yoshizawa, S1
Teixeira, OH1
Martin, L1
Carpenter, BF1
Sellers, FJ1
Rainsford, KD3
Whitehouse, MW3
Wirth, PW1
Watson, ES1
ElSohly, M1
Turner, CE1
Murphy, JC1
Lopez-Anaya, A1
Dawson, C1
Gonzales, C1
Bacolod, M1
Kishore, V2
Ozkanli, F1
Pilli, G1
Demirdamar, R1
Gümüşel, B1
Isakson, P1
Seibert, K1
Masferrer, J1
Salvemini, D1
Lee, L1
Needleman, P1
Satyanarayana, K1
Rao, MN1
Saeed, SA2
Simjee, RU2
Rahman, NN1
Zuany-Amorim, C1
Cordeiro, RS4
Ahmad, F1
Khan, RA1
Rasheed, S1
Dauksas, V1
Kuliesius, V1
Valencia, E1
Feria, M1
Díaz, JG1
González, A1
Bermejo, J1
Farnaz, S1
Malik, A1
Galzigna, L1
Licit, L1
De Pieri, GF1
Bonora, GM1
Signor, A1
Yokota, K1
Yamamoto, N1
Morimoto, Y1
Yamashita, A1
Oda, M1
Braithwaite, BD1
Petrik, PV1
Moore, WS1
Gelabert, H1
Pollen, DN1
Earnshaw, JJ1
Quinones-Baldrich, WJ1
Khaksa, G1
Zolfaghari, ME1
Dehpour, AR1
Samadian, T1
Lariviere, WR1
Melzack, R1
Ueno, Y1
Koike, H1
Annoh, S1
Nishio, S1
Martínez-Vázquez, M1
Ramírez Apan, TO1
Lastra, AL1
Bye, R1
Panthong, A1
Kanjanapothi, D1
Thitiponpunt, Y1
Taesotikul, T1
Arbain, D1
Alaoui, K1
Lagorce, JF1
Cherrah, Y1
Hassar, M1
Amarouch, H1
Roquebert, J1
Takeuchi, K1
Suzuki, K1
Yamamoto, H1
Araki, H1
Mizoguchi, H1
Ukawa, H1
Fong, DS1
Barton, FB1
Bresnick, GH1
al-Swayeh, OA1
Clifford, RH1
del Soldato, P1
Moore, PK1
Cechinel-Filho, V1
Vaz, ZR1
Zunino, L1
Yunes, RA1
Taylor, GN1
Singh, PN1
Hollingsworth, SJ1
Dialysis, M1
Barker, SG1
Boyle, E1
Freeman, PC1
Goudie, AC1
Mangan, FR1
Thomson, M1
Bonta, IL1
Bult, H1
Vincent, JE1
Zijlstra, FJ1
Sofia, RD5
Diamantis, W2
Ludwig, BJ1
Volon, G1
Lorenzetti, BB2
Corrêa, FM1
Grayson, MF1
Moncada, S1
Vane, JR3
Kubota, T1
Komatsu, H1
Kawamoto, H1
Yamada, T1
Smith, MJ1
Ford-Hutchinson, AW1
Walker, JR1
Slack, JA1
Tarzia, G1
Panzone, G1
Maruyama, Y2
Imayoshi, T1
Foto, K1
Kadobe, Y1
Harrop-Griffiths, H1
Petricevic, M1
Wanek, K1
Denko, CW1
Wiseman, EH4
Chang, YH2
Hobbs, DC1
Ziel, R1
Krupp, P1
Sveen, K1
Gilhuus-Moe, O1
Jacker, HJ2
Aparicio, L1
Meacock, SC1
Kitchen, EA1
Nelson, PH1
Bartsch, GA1
Untch, KG1
Fried, JH1
Adams, SS1
McCullough, KF1
Nicholson, JS1
Weischer, CH1
Salem, H1
Dunn, BJ1
Loux, JJ1
Peterfalvi, M1
Deraedt, R1
Benzoni, J1
Chifflot, L1
Fournex, R1
Kambayashi, Y1
Mizushima, Y1
Dorfman, RI1
Fregnan, GB2
Subissi, A1
Torsello, AL2
Giri, SN1
Rice, S1
Bacchetti, P1
Niemegeers, CJ1
Awouters, F1
Lenaerts, FM1
Janssen, PA1
Teng, CM2
Hsu, MF1
Wang, JP2
Calhoun, W1
Gilman, SC1
Datko, LJ1
Copenhaver, TW1
Carlson, RP1
Matsuda, R1
Tanihata, S1
Perretti, M1
Mugridge, KG1
Wallace, JL1
Parente, L1
Amorim, CZ1
Weg, VB1
Toppozada, M2
Darwish, EA1
Osman, YF1
Abd-Rabbo, MS1
Spyriounis, DM1
Rekka, E1
Demopoulos, VJ1
Kourounakis, PN1
Khowessah, M1
Shaala, S1
Abd-Rabbo, S1
Zoheir, A1
Whelan, CJ1
Head, SA1
Poll, CT1
Coleman, RA1
Bravo, L1
Escolar, G1
Navarro, C1
Fontarnau, R1
Bulbena, O1
Chaudhary, KP1
Roy, A1
Lahiri, SC1
Gallardo, F1
Carstens, M1
Ayarza, M1
Abignente, E1
Arena, F1
Luraschi, E1
De Caprariss, P1
Marmo, E1
Vitagliano, S1
Donnoli, D1
Hirschelmann, R1
Silva, PM2
Martins, MA2
Mburu, DN1
Mbugua, SW1
Skoglund, LA1
Lökken, P1
Jenner, PN1
Hattori, T1
Tokugawa, K1
Fukushige, J1
Tasaki, H1
Nanri, T1
Ueda, K1
Pirisino, R1
Bianchini, F1
Banchelli, G1
Ignesti, G1
Raimondi, L1
Pecori-Vettori, L1
Rafanelli, D1
Castro, HC1
Neto, F1
Lima, MC1
Telias, ID1
Zvi, ZB1
Danon, A1
Puig Parellada, P1
Killackey, JJ1
Killackey, BA1
Philp, RB1
Soschin, D1
Leyden, JJ1
Poisson, M1
Ralambosoa, C1
Blehaut, H1
Astoin, J1
Wilhelmi, G1
Menassé-Gdynia, R1
Garcia Leme, J1
Hamamura, L1
Leite, MP1
Rocha e Silva, M1
Fontaine, L1
Grand, M1
Quentin, Y1
Merle, S1
Dixon, JR1
Mountain, JT1
Tsuji, H1
Aizawa, Y1
Iwasaki, M1
Goldberg, AS1
Mueller, EC1
Eigen, E1
Desalva, SJ1
Mörsdorf, K1
Anspach, K1
Alphin, RS1
Mielens, ZE1
Drobeck, HP1
Rozitis, J1
Sansone, VJ1
Kobayashi, S1
Takagi, H1
Bhalla, TN1
Tangri, KK1
Takagi, K1
Takayanagi, I1
Kayaoka, S1
Hirai, T1
Lee, EB1
Rosenthale, ME1
Begany, AJ1
Dervinis, A1
Malis, JL1
Shriver, DA1
Datko, SL1
Gluckman, MI1
Sobański, H1
Krupinńska, J1
Gryglewski, RJ1
Dodge, PW2
Kimura, ET2
Brunet, S1
Go, K1
Hiramatsu, Y1
Tamura, Y1
Lerner, LJ1
Diena, A1
Sardi, A1
Maffii, G1
Flower, R1
Gryglewski, R1
Herbaczyńska-Cedro, K1
Watillon, M1
Robe-Vanwijck, A1
Gordon, R1
Kletzkin, M1
Berger, FM1
Edelson, J1
Singer, H1
Douglas, JF1
Nalepa, SD2
Vassar, HB2
Knobloch, LC1
Roszkowski, AP2
Rooks, W1
Tomolonis, A1
Miller, L1
Pelczarska, AB1
van der Molen, HR1
Töth, LM1
Vinegar, R3
Truax, JF1
Selph, JL1
Rassaert, CL1
Richter, RS1
Martin, J1
DiPasquale, G2
Harakal, JJ1
Rassaert, C1
Richter, R1
Welaj, P1
Tripp, L1
Kosersky, DS1
Dewey, WL1
Harris, LS1
Puig-Parellada, P1
García-Gasulla, G1
Puig-Muset, P1
Nozaki, M1
Hayashi, M1
Nakano, K1
Lambelin, G1
Roba, J1
Gillet, C1
Buu-Hoï, NP1
Fischer, J1
Rohloff, N1
Sweit, LR1
Langford, FD1
Holmes, PA1
Emele, JF1
Dolbeare, FA1
Martlage, KA1
Tanaka, K1
Iizuka, Y1
Restelli, A1
Rooks, WH1
Miller, LM1
Lombardino, JG2
Riesterer, L1
Majer, H1
Jaques, R1
Swingle, KF2
Hamilton, RR1
Harrington, JK1
Kvam, DC2
Walz, DT2
Dolan, MM1
DiMartino, MJ1
Yankell, SL1
Friedman, H1
Di Rosa, M1
Papadimitriou, JM1
Willoughby, DA1
Lexomboon, U1
Goth, A1
Finkelstein, RA1
Samter, M1
Beers, RF1
Brown, K1
Cavalla, JF1
Green, D2
Wilson, AB2
Di Martino, MJ1
Griffin, CL1
Misher, A1
Faggioli, F1
Gasbarrini, G1
Scondotto, G1
Mattei, M1
Zanetti, A1
Atkinson, DC1
Boura, AL1
Hicks, R1
Liu, CT1
Grant, TJ1
Jaques, LW1
Aberg, G1
Larsson, KS1
Nakamura, H1
Kadokawa, T1
Nakatsuji, K1
Nakamura, K1
Nakanishi, M1
Imamura, H1
Green, AY1
Murray, PA1
Chang, YC1
Malone, MH1
Barron, DI1
Copley, AR1
Vallance, DK1
Pepper, H1
Piliero, SJ1
Colombo, C1
Schreiber, W1
Hugo, R1
Sancilio, LF1
Pircio, AW1
Groskinsky, EJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)[NCT02409680]11,976 participants (Actual)Interventional2016-03-23Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Fetal Outcome 1 - Incidence of Early Preterm Delivery (<34 Weeks)

- Early preterm delivery (<34 weeks) (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm189
Placebo Arm230

Fetal Outcome 2 - Incidence of Actual Birth Weight <2500g

- Birth weight <2500g (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm1078
Placebo Arm1153

Fetal Outcome 3 - Incidence of Actual Birth Weight <1500g

- Birth weight <1500g (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm78
Placebo Arm101

Fetal Outcome 4 - Incidence of Fetal Loss

- Incidence of Fetal Loss (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm303
Placebo Arm353

Fetal Outcome 5 - Incidence of Spontaneous Abortion

- Incidence of Spontaneous Abortion (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm134
Placebo Arm152

Fetal Outcome 6 - Incidence of All Stillbirth

- Incidence of All stillbirth (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm141
Placebo Arm166

Fetal Outcome 7 - Incidence of Medical Termination of Pregnancy

- Incidence of Medical Termination of Pregnancy (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm42
Placebo Arm30

Incidence of Hypertensive Disorders of Pregnancy

- Hypertensive disorders of pregnancy is defined by the characterization of evidence of a hypertensive disorder, including either preeclampsia or eclampsia occurring during the pregnancy. (NCT02409680)
Timeframe: Evidence of hypertensive disorder during the pregnancy (prior to delivery/birth)

InterventionParticipants (Count of Participants)
Intervention Arm352
Placebo Arm325

Incidence of Perinatal Mortality

- Incidence of Perinatal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm264
Placebo Arm309

Incidence of Preterm Birth

The primary outcome of this study is incidence of preterm birth, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks. This will be determined based on actual date of delivery in comparison to the projected estimated due date (EDD), independent of whether or not the preterm delivery is indicated or spontaneous. (NCT02409680)
Timeframe: At delivery

InterventionParticipants (Count of Participants)
Intervention Arm668
Placebo Arm754

Incidence of Small for Gestational Age (SGA)

- Small for gestational age (SGA) as defined by the INTERGROWTH-21st standard (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm1506
Placebo Arm1564

Maternal Outcome 1 - Incidence of Vaginal Bleeding

- Vaginal bleeding (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm214
Placebo Arm246

Maternal Outcome 2 - Incidence of Antepartum Hemorrhage

- Antepartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm26
Placebo Arm25

Maternal Outcome 3 - Incidence of Postpartum Hemorrhage

- Postpartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm54
Placebo Arm43

Maternal Outcome 4 - Incidence of Maternal Mortality

- Incidence of Maternal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm9
Placebo Arm12

Maternal Outcome 5 - Incidence of Late Abortion

- Incidence of Late Abortion (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm23
Placebo Arm30

Maternal Outcome 6 - Change in Maternal Hemoglobin

Hemoglobin < 7.0 gm/dl at 26-30 weeks gestation or a drop of 3.5+ gm/dl from screening to 26-30 weeks gestation (NCT02409680)
Timeframe: At enrollment, 4 weeks post enrollment, and 26-30 weeks GA.

InterventionParticipants (Count of Participants)
Intervention Arm290
Placebo Arm333

Maternal Outcome 7 - Incidence of Preterm, Preeclampsia

Early preterm delivery (<34 weeks) and hypertensive disorders (i.e.: preeclampsia) (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery

InterventionParticipants (Count of Participants)
Intervention Arm8
Placebo Arm21

Reviews

11 reviews available for aspirin and Edema

ArticleYear
Gallbladder Hydrops Associated With Kawasaki Disease: A Case Report and Literature Review.
    Clinical pediatrics, 2018, Volume: 57, Issue:3

    Topics: Aspirin; Child; Edema; Follow-Up Studies; Gallbladder Diseases; Humans; Immunoglobulins, Intravenous

2018
Retropharyngeal involvement in Kawasaki disease--a report of four patients with retropharyngeal edema verified by magnetic resonance imaging.
    International journal of pediatric otorhinolaryngology, 2014, Volume: 78, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Edema; Humans; Immunoglob

2014
Ultrasonographic resolution of the vessel wall oedema with modest clinical improvement in a large-vessel vasculitis patient treated with tocilizumab.
    Clinical rheumatology, 2012, Volume: 31, Issue:8

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Aspirin; Biopsy;

2012
[Renal and cardiovascular effects of non-steroidal anti-inflammatories and selective cox 2 inhibitors].
    Presse medicale (Paris, France : 1983), 2004, Apr-10, Volume: 33, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relations

2004
Appropriate use of NSAIDs: considering cardiovascular risk in the elderly.
    Geriatrics, 2007, Volume: 62, Issue:3

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2 In

2007
The diabetic retinopathy study and the early treatment diabetic retinopathy study.
    International ophthalmology clinics, 1984,Winter, Volume: 24, Issue:4

    Topics: Adult; Aspirin; Clinical Trials as Topic; Diabetic Retinopathy; Edema; Follow-Up Studies; Humans; La

1984
Discovery of a better aspirin.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Carra

1995
Mode of action of aspirin-like drugs.
    Advances in internal medicine, 1979, Volume: 24

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Chemical Phenomena; Chemistry;

1979
The mode of action of aspirin and similar compounds.
    The Journal of allergy and clinical immunology, 1976, Volume: 58, Issue:6

    Topics: Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Bronchi; Dermatitis, Atopic; Drug Hypersensiti

1976
Facial palsy in Kawasaki disease. Report of two cases and a review.
    European journal of pediatrics, 1987, Volume: 146, Issue:6

    Topics: Aspirin; Edema; Facial Paralysis; Female; Humans; Infant; Mucocutaneous Lymph Node Syndrome

1987
Pharmacological properties of naproxen.
    Scandinavian journal of rheumatology. Supplement, 1973, Volume: 2

    Topics: Administration, Oral; Administration, Topical; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory A

1973

Trials

13 trials available for aspirin and Edema

ArticleYear
Unilateral conjunctival chemosis as a unique symptom of nonsteroidal anti-inflammatory drug intolerance.
    Journal of investigational allergology & clinical immunology, 2007, Volume: 17, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Conjunctival Diseases; Dipyrone; Edema; Humans; Ma

2007
The effects of acetylsalicylic acid on swelling, pain and other events after surgery.
    British journal of clinical pharmacology, 1984, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Aspirin; Body Temperature; Clinical Trials as Topic; Double-Blind Method; Edema;

1984
The diabetic retinopathy study and the early treatment diabetic retinopathy study.
    International ophthalmology clinics, 1984,Winter, Volume: 24, Issue:4

    Topics: Adult; Aspirin; Clinical Trials as Topic; Diabetic Retinopathy; Edema; Follow-Up Studies; Humans; La

1984
[Anti-edematous pharmacotherapy in ambulatory oral surgery].
    Stomatologie der DDR, 1984, Volume: 34, Issue:8

    Topics: Adolescent; Adult; Ascorbic Acid; Aspirin; Edema; Humans; Mouth; Phenylbutazone; Postoperative Compl

1984
The early treatment diabetic retinopathy study.
    Transactions - Pennsylvania Academy of Ophthalmology and Otolaryngology, 1982,Spring, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Diabetic Retinopathy; Edema; Fluorescein

1982
Impaired color vision associated with diabetic retinopathy: Early Treatment Diabetic Retinopathy Study Report No. 15.
    American journal of ophthalmology, 1999, Volume: 128, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Aspirin; Color; Color Perception; Diabetic Retinopathy; Discriminati

1999
"Long haul" flight and deep vein thrombosis: a model to help investigate the benefit of aspirin and below-knee compression stockings.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2001, Volume: 22, Issue:5

    Topics: Adult; Aerospace Medicine; Aspirin; Bandages; Edema; Female; Humans; Leg; Male; Platelet Aggregation

2001
A clinical trial of diflunisal against aspirin in osteoarthritis.
    Rheumatology and rehabilitation, 1978, Volume: 17, Issue:4

    Topics: Abdomen; Aspirin; Clinical Trials as Topic; Dizziness; Double-Blind Method; Drug Administration Sche

1978
Paracetamol/codeine in relieving pain following removal of impacted mandibular third molars.
    International journal of oral surgery, 1975, Volume: 4, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Aspirin; Codeine; Drug Therapy, Combination; Edema; Female; Humans

1975
Low dose acetyl salicylic acid in severe preeclampsia.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1991, Volume: 35, Issue:4

    Topics: Albuminuria; Aspirin; Blood Pressure; Edema; Female; Humans; Pre-Eclampsia; Pregnancy

1991
Analgesic and antiinflammatory effects of glucamethacin (a nonsteroidal antiinflammatory analgesic) after the removal of impacted third molars.
    Oral surgery, oral medicine, and oral pathology, 1990, Volume: 69, Issue:2

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chi-Square Distribution; Double

1990
Nabumetone in the treatment of skin and soft tissue injury.
    The American journal of medicine, 1987, Oct-30, Volume: 83, Issue:4B

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butano

1987
Naproxen (Naprosyn) and ketoprofen (Orudis).
    Drug and therapeutics bulletin, 1974, Mar-29, Volume: 12, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzophenones; Clinical Trials as

1974

Other Studies

325 other studies available for aspirin and Edema

ArticleYear
2-(Substituted phenyl)oxazolo[4,5-b]pyridines and 2-(substituted phenyl)oxazolo[5,4-b]pyridines as nonacidic antiinflammatory agents.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1978
Synthesis and analgesic-antiinflammatory activity of some 4- and 5-substituted heteroarylsalicylic acids.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry, Physical; Dogs; Ede

1978
Glycerides as prodrugs. 1. Synthesis and antiinflammatory activity of 1,3-bis(alkanoyl)-2-(O-acetylsalicyloyl)glycerides (aspirin triglycerides).
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Do

1979
Synthesis of carboxyarylindoles and benzofurans as nonsteroidal antiinflammatory agents.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Benzofurans; Edema; Indoles; Male; Rats; Structure-Activity Relat

1977
3-Aryl-as-triazines as potential antiinflammatory agents.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Edema; Rats; Triazines

1977
Biologically oriented organic sulfur chemistry. 14. Antiinflammatory properties of some aryl sulfides, sulfoxides, and sulfones.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Edema; Erythema; Female; Male; Mice; Rats; Structure-Activity Rel

1976
Synthesis and antiinflammatory properties of N-substituted 4,5-dioxopyrrolidine-3-carboxanilides.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:1

    Topics: Anilides; Animals; Anti-Inflammatory Agents; Aspirin; Edema; Pyrrolidines; Rats

1976
Carboxyarylindoles as nonsteroidal antiinflammatory agents.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Indoles; Male; Rats; Structure-Activity Relat

1976
Synthesis of 3-(2-pyridylethyl)benzoxazolinone derivatives: potent analgesic and antiinflammatory compounds inhibiting prostaglandin E2.
    Journal of medicinal chemistry, 1992, Apr-03, Volume: 35, Issue:7

    Topics: Analgesia; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; A

1992
Synthesis and antiinflammatory and analgesic activity of 5-aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-ca rboxyl ic acids and 1-methyl-4-(methylthio)-5-aroylpyrrole-2-acetic acids.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Acetates; Analgesia; Animals; Aspirin; Benzoquinones; Carboxylic Acids; Carrageenan; Chemical Phenom

1989
Benzimidazole derivatives with atypical antiinflammatory activity.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Benzimidazoles

1987
3-Alkyl-2-aryl-3H-naphth[1,2-d]imidazoles, a novel class of nonacidic antiinflammatory agents.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Drug Evaluation, Preclini

1984
Glycerides as prodrugs. 2. 1,3-Dialkanoyl-2-(2-methyl-4-oxo-1,3-benzodioxan-2-yl)glycerides (cyclic aspirin triglycerides) as antiinflammatory agents.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Male; Rats; Salicylates; Stomach Ulc

1980
Synthesis and pharmacological evaluation of 2,5-cycloamino-5H-[1]benzopyrano[4,3-d]pyrimidines endowed with in vitro antiplatelet activity.
    Bioorganic & medicinal chemistry letters, 2001, Jun-04, Volume: 11, Issue:11

    Topics: Adenosine Diphosphate; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Benzopyrans;

2001
A new class of ibuprofen derivatives with reduced gastrotoxicity.
    Journal of medicinal chemistry, 2001, Oct-11, Volume: 44, Issue:21

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclic N-Oxides; Edema; Gastric Mucos

2001
Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Journal of medicinal chemistry, 2006, Mar-09, Volume: 49, Issue:5

    Topics: Administration, Oral; Alkynes; Analgesics; Animals; Arachidonate 15-Lipoxygenase; Carrageenan; Cyclo

2006
Analgesic agents without gastric damage: design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selective inhibitors.
    Bioorganic & medicinal chemistry, 2007, Jan-15, Volume: 15, Issue:2

    Topics: Analgesics; Anilides; Animals; Benzenesulfonates; Carrageenan; Colorimetry; Crystallography, X-Ray;

2007
Synthesis and crystallographic analysis of benzophenone derivatives--the potential anti-inflammatory agents.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Carrageenan; Crystallography, X-Ray

2007
2-Amino-5-thiazolyl motif: a novel scaffold for designing anti-inflammatory agents of diverse structures.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chronic Disease; Cyclooxygenase Inhib

2008
Toward the development of chemoprevention agents. Part 1: Design, synthesis, and anti-inflammatory activities of a new class of 2,5-disubstituted-dioxacycloalkanes.
    Bioorganic & medicinal chemistry, 2007, Jul-15, Volume: 15, Issue:14

    Topics: Animals; Anti-Inflammatory Agents; Bleeding Time; Chemoprevention; Cycloparaffins; Drug Design; Edem

2007
1-Acylthiosemicarbazides, 1,2,4-triazole-5(4H)-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones: synthesis, analgesic-anti-inflammatory and antimicrobial activities.
    Bioorganic & medicinal chemistry, 2007, Sep-01, Volume: 15, Issue:17

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Benzoxazoles; Crystallography,

2007
Toward the development of chemoprevention agents. Part II: Chemo-enzymatic synthesis and anti-inflammatory activities of a new class of 5-amino-2-substitutedphenyl-1,3-dioxacycloalkanes.
    Bioorganic & medicinal chemistry, 2007, Sep-15, Volume: 15, Issue:18

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Bleeding Time; Cell Membrane Permeability; Chemopreventi

2007
A new therapeutic approach in Alzheimer disease: some novel pyrazole derivatives as dual MAO-B inhibitors and antiinflammatory analgesics.
    Bioorganic & medicinal chemistry, 2007, Sep-01, Volume: 15, Issue:17

    Topics: Alzheimer Disease; Analgesics; Animals; Anti-Inflammatory Agents; Edema; Hindlimb; Hydrogen Bonding;

2007
Aromatic amide derivatives of 5,6-dimethoxy-2,3-dihydro-1H-inden(-1-yl)acetic acid as anti-inflammatory agents free of ulcerogenic liability.
    Bioorganic & medicinal chemistry letters, 2007, Dec-15, Volume: 17, Issue:24

    Topics: Acetates; Amides; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Carrageenan; Cytochrome

2007
Searching for new NO-donor aspirin-like molecules: a new class of nitrooxy-acyl derivatives of salicylic acid.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aspirin; Carrageenan; Drug Evalua

2008
Second-generation aspirin and indomethacin prodrugs possessing an O(2)-(acetoxymethyl)-1-(2-carboxypyrrolidin-1-yl)diazenium-1,2-diolate nitric oxide donor moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azo Compounds; Carr

2008
Synthesis and biological evaluation of 1-(benzenesulfonamido)-2-[5-(N-hydroxypyridin-2(1H)-one)]acetylene regioisomers: a novel class of 5-lipoxygenase inhibitors.
    Bioorganic & medicinal chemistry letters, 2008, Jul-15, Volume: 18, Issue:14

    Topics: Acetylene; Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Chemistry, Pharmaceutical

2008
Synthesis and anti-inflammatory activity of 2-(2-aroylaroxy)-4,6-dimethoxy pyrimidines.
    Bioorganic & medicinal chemistry letters, 2008, Aug-01, Volume: 18, Issue:15

    Topics: Algorithms; Animals; Animals, Inbred Strains; Anti-Inflammatory Agents, Non-Steroidal; Disease Model

2008
Synthesis and anti-inflammatory activity of 2-aryloxy methyl oxazolines.
    Bioorganic & medicinal chemistry letters, 2008, Aug-15, Volume: 18, Issue:16

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Chemistry, Pharmaceutical; Drug Design; Edema; Ethan

2008
Synthesis of new 4-[2-(4-methyl(amino)sulfonylphenyl)-5-trifluoromethyl-2H-pyrazol-3-yl]-1,2,3,6-tetrahydropyridines: a search for novel nitric oxide donor anti-inflammatory agents.
    Bioorganic & medicinal chemistry, 2008, Oct-01, Volume: 16, Issue:19

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Celecoxib; Edema; Inflammation; Nitric Oxid

2008
Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Bioorganic & medicinal chemistry letters, 2008, Dec-01, Volume: 18, Issue:23

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Celecoxib; Cy

2008
New acyclic nucleosides analogues as potential analgesic, anti-inflammatory, anti-oxidant and anti-microbial derived from pyrimido[4,5-b]quinolines.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Bacteria; Carrag

2009
Synthesis and pharmacological evaluation of a novel series of 5-(substituted)aryl-3-(3-coumarinyl)-1-phenyl-2-pyrazolines as novel anti-inflammatory and analgesic agents.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Design; Edema; Female; Male; Mic

2009
Synthesis and pharmacological evaluation of 1,3,4-oxadiazole bearing bis(heterocycle) derivatives as anti-inflammatory and analgesic agents.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:10

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Edema; Female; Male; Mice; Molecular Structure; Oxadi

2009
Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies.
    Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14

    Topics: Animals; Anti-Inflammatory Agents; Azo Compounds; Cyclooxygenase Inhibitors; Edema; Foot; Humans; Ni

2009
Synthesis and analgesic and anti-inflammatory activities 6-substituted-3(2H)-pyridazinone-2-acetyl-2-(p-substituted/nonsubstituted benzal)hydrazone derivatives.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:9

    Topics: Abdominal Pain; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Hydrazones; Inf

2009
Synthesis of 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as novel analgesic/anti-inflammatory compounds.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Edema; Female; Male; Mice;

2009
Synthesis and pharmacological evaluation of novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives as anti-inflammatory and analgesic agents.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzimidazoles; Carrageenan; Edema; Male; Mice; Rats;

2010
A class of novel Schiff's bases: Synthesis, therapeutic action for chronic pain, anti-inflammation and 3D QSAR analysis.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Chronic Disease; Disease Models, Animal; Ea

2010
3-Formylchromones: potential antiinflammatory agents.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chromones; Cyclooxygenase Inhibitors;

2010
Novel β-carboline-tripeptide conjugates attenuate mesenteric ischemia/reperfusion injury in the rat.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbolines; Crystallography, X-Ray; Dose-Response

2011
Searching for new NO-donor aspirin-like molecules: Furoxanylacyl derivatives of salicylic acid and related furazans.
    Bioorganic & medicinal chemistry, 2011, Oct-01, Volume: 19, Issue:19

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Collagen; Cyclooxygenase 1; Cyclooxygenase 2; Disease Mo

2011
Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors.
    Bioorganic & medicinal chemistry, 2011, Nov-01, Volume: 19, Issue:21

    Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Cyclooxygenase 2; Cyclooxygenase 2 I

2011
Nitric oxide release is not required to decrease the ulcerogenic profile of nonsteroidal anti-inflammatory drugs.
    Journal of medicinal chemistry, 2012, Jan-26, Volume: 55, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Cyclooxygenase 1; Cyclooxy

2012
Synthesis of new 5,6-dihydrobenzo[h]quinazoline 2,4-diamino substituted and antiplatelet/antiphlogistic activities evaluation.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Dose-Response Relationshi

2012
Design, synthesis, and evaluation of a novel class of 2,3-disubstituted-tetrahydro-β-carboline derivatives.
    Bioorganic & medicinal chemistry letters, 2012, Jun-01, Volume: 22, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Carbolines; Drug Design; Edema; Glucosamine; Mice; Tryptophan; Xy

2012
Synthesis, characterization and biological studies of diosgenyl analogues.
    Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dios

2012
PEG mediated synthesis and pharmacological evaluation of some fluoro substituted pyrazoline derivatives as antiinflammatory and analgesic agents.
    Bioorganic & medicinal chemistry letters, 2013, May-01, Volume: 23, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Edema; Fluorine; Polyethylene Glycols; Pyrazoles; Rat

2013
Synthesis and biological evaluation of N-dehydrodipeptidyl-N,N'-dicyclohexylurea analogs.
    European journal of medicinal chemistry, 2014, May-06, Volume: 78

    Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; An

2014
Synthesis, pharmacological screening and in silico studies of new class of Diclofenac analogues as a promising anti-inflammatory agents.
    Bioorganic & medicinal chemistry, 2014, May-15, Volume: 22, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Computer Simulation; Cyclooxygenase 1

2014
1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10H-
    European journal of medicinal chemistry, 2014, Oct-30, Volume: 86

    Topics: Amides; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cells, Cultured;

2014
Design, synthesis and evaluation of a novel class of glucosamine mimetic peptides containing 1,3-dioxane.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: Animals; Anti-Inflammatory Agents; Dioxanes; Drug Design; Edema; Glucosamine; Male; Mice; Mice, Inbr

2015
Anti-inflammatory, analgesic and antioxidant activities of novel kyotorphin-nitroxide hybrid molecules.
    Bioorganic & medicinal chemistry letters, 2016, Apr-15, Volume: 26, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Dose-Response Relationsh

2016
Pharmacological protection of mitochondrial function mitigates acute limb ischemia/reperfusion injury.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Animals; Anti-Inflammatory Agents; Curcumin; Cytochromes c; Disease Models, Animal; Edema; Enzyme-Li

2016
Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation.
    Bioorganic & medicinal chemistry, 2017, 01-01, Volume: 25, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase Inhib

2017
Design, synthesis, biological evaluation, and molecular docking of chalcone derivatives as anti-inflammatory agents.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Chalcone; Cyclooxygenase 2; Drug Design; Edema; In

2017
Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents.
    European journal of medicinal chemistry, 2020, Jan-15, Volume: 186

    Topics: Albumins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Carrageenan

2020
Analagesic and Anti-Inflammatory Potentials of a Less Ulcerogenic Thiadiazinethione Derivative in Animal Models: Biochemical and Histochemical Correlates.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Car

2022
FM0807 decelerates experimental arthritis progression by inhibiting inflammatory responses and joint destruction via modulating NF-κB and MAPK pathways.
    Bioscience reports, 2019, 09-30, Volume: 39, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Curcumin; Disease Progression;

2019
Gastrointestinal and uterine smooth muscles relaxant and anti-inflammatory effects of corchorus olitorius leaf extract in laboratory animal models.
    Journal of ethnopharmacology, 2020, Jan-30, Volume: 247

    Topics: Abortion, Spontaneous; Animals; Anti-Inflammatory Agents; Antidiarrheals; Aspirin; Corchorus; Diarrh

2020
Kawasaki Disease Presenting as Hydrops of the Gallbladder.
    Clinical pediatrics, 2020, Volume: 59, Issue:4-5

    Topics: Aspirin; Diagnosis, Differential; Diagnostic Imaging; Edema; Female; Gallbladder Diseases; Humans; I

2020
A Rare Finding of Upper Limb Deep Venous Thrombosis in a Patient with COVID-19.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:6

    Topics: Anticoagulants; Arm; Aspirin; Betacoronavirus; Coronavirus Infections; COVID-19; Edema; Enoxaparin;

2020
Acute cholestasis as uncommon onset of Kawasaki disease: a case report.
    BMC gastroenterology, 2020, Oct-28, Volume: 20, Issue:1

    Topics: Adult; Aspirin; Child; Child, Preschool; Cholestasis; Edema; Fever; Humans; Male; Mucocutaneous Lymp

2020
Comparison of analgesic activities of aconitine in different mice pain models.
    PloS one, 2021, Volume: 16, Issue:4

    Topics: Acetic Acid; Aconitine; Analgesics; Animals; Aspirin; Disease Models, Animal; Edema; Female; Formald

2021
Complete Kawasaki disease (KD) with peculiar skin manifestations.
    BMJ case reports, 2017, Oct-09, Volume: 2017

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cheilitis; Conjunctival Diseases; Edema; Female; F

2017
Monoacylglycerol lipase inhibitor, JZL-184, confers neuroprotection in the mice middle cerebral artery occlusion model of stroke.
    Life sciences, 2018, Apr-01, Volume: 198

    Topics: Animals; Aspirin; Behavior, Animal; Benzodioxoles; Brain; Brain Edema; Brain Ischemia; Disease Model

2018
Long-haul flights, edema, and thrombotic events: prevention with stockings and Pycnogenol® supplementation (LONFLIT Registry Study).
    Minerva cardioangiologica, 2018, Volume: 66, Issue:2

    Topics: Adult; Aircraft; Aspirin; Edema; Female; Flavonoids; Humans; Male; Middle Aged; Plant Extracts; Plat

2018
Methanolic Extract of Leathery Murdah, Terminalia coriacea (Roxb.) Wight and Arn. Leaves Exhibits Anti-Inflammatory Activity in Acute and Chronic Models.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2018, Volume: 27, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Disease Models, Animal; Dose-Response Relationship, Drug

2018
The new plant Parinari kerstingii Engl.: Toxicity studies and anti-inflammatory properties.
    Journal of ethnopharmacology, 2018, Jun-28, Volume: 220

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Chrysobalanaceae; Disease Models, Animal; D

2018
ANTI-INFLAMMATORY ACTIVITY OF SODIUM SALT OF 4-(O-β-D-GLUCOPYRANOSYLOXY)BENZOIC ACID.
    Eksperimental'naia i klinicheskaia farmakologiia, 2016, Volume: 79, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Drug Administration Schedule

2016
Dyspnea and Edema in a Woman With Antiphospholipid Syndrome.
    JAMA cardiology, 2018, 11-01, Volume: 3, Issue:11

    Topics: Antiphospholipid Syndrome; Aspirin; Dyspnea; Echocardiography; Edema; Female; Fluoroscopy; Heart Fai

2018
Acute peritonsillar swelling: a unique presentation for Kawasaki disease in adolescence.
    BMJ case reports, 2018, Jul-24, Volume: 2018

    Topics: Adolescent; Airway Obstruction; Aspirin; Diagnosis, Differential; Drug Therapy, Combination; Edema;

2018
Protective roles of Vigna subterranea (Bambara nut) in rats with aspirin-induced gastric mucosal injury.
    Journal of integrative medicine, 2018, Volume: 16, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Edema; Gastric Mucosa; Gastrointestinal Agents; G

2018
Effect of anti-inflammatory activity of ranolazine in rat model of inflammation.
    The Indian journal of medical research, 2018, Volume: 148, Issue:6

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Edema; Granul

2018
Olive-Derived Hydroxytyrosol Shows Anti-inflammatory Effect without Gastric Damage in Rats.
    Biological & pharmaceutical bulletin, 2019, Volume: 42, Issue:7

    Topics: Animals; Aspirin; Carrageenan; Celecoxib; Cyclooxygenase 2 Inhibitors; Dinoprostone; Edema; Gastric

2019
Anti-inflammatory effects of essential oil in Echinacea purpurea L.
    Pakistan journal of pharmaceutical sciences, 2013, Volume: 26, Issue:2

    Topics: Albumins; Animals; Anti-Inflammatory Agents; Aspirin; Cotton Fiber; Disease Models, Animal; Distilla

2013
Activation of a retinoic acid receptor pathway by thiazolidinediones induces production of vascular endothelial growth factor/vascular permeability factor in OP9 adipocytes.
    European journal of pharmacology, 2013, May-05, Volume: 707, Issue:1-3

    Topics: Adipocytes; Animals; Aspirin; Capillary Permeability; Cell Differentiation; Cells, Cultured; Chroman

2013
Evaluation of the in vivo anti-inflammatory and analgesic and in vitro anti-cancer activities of curcumin and its derivatives.
    Natural product communications, 2013, Volume: 8, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Cell Line; Cell Line, Tumor; Curcumin; Edema

2013
Water-soluble nitric-oxide-releasing acetylsalicylic acid (ASA) prodrugs.
    ChemMedChem, 2013, Volume: 8, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Edema; Humans; Male; Molecular Structure;

2013
Transdermal enhancement effect and mechanism of iontophoresis for non-steroidal anti-inflammatory drugs.
    International journal of pharmaceutics, 2014, May-15, Volume: 466, Issue:1-2

    Topics: 1-Octanol; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Car

2014
Synergistic interaction between choline and aspirin against acute inflammation induced by carrageenan and lipopolysaccharide.
    International immunopharmacology, 2014, Volume: 20, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Choline; Cytokines; Drug Synergism; Edema;

2014
Assessment of pharmacological activities of two medicinal plant of Bangladesh: Launaea sarmentosa and Aegialitis rotundifolia roxb in the management of pain, pyrexia and inflammation.
    Biological research, 2014, Oct-28, Volume: 47

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Aspirin; Asteraceae; Ban

2014
Partial segmental thrombosis of the corpus cavernosum (PSTCC) diagnosed by contrast-enhanced ultrasound: a case report.
    BMC urology, 2014, Dec-17, Volume: 14

    Topics: Adult; Anticoagulants; Aspirin; Contrast Media; Edema; Enoxaparin; Humans; Male; Pain; Penile Diseas

2014
Experimental evaluation of anti-inflammatory, antinociceptive and antipyretic activities of clove oil in mice.
    The Libyan journal of medicine, 2015, Volume: 10, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Aspirin; Clove Oil; Disease Models, Ani

2015
[The mechanism of anthocyanin to anti-inflammatory and analgesic frnm Ligustrum fruit].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2015, Volume: 31, Issue:5

    Topics: Analgesics; Animals; Anthocyanins; Anti-Inflammatory Agents; Antioxidants; Aspirin; Dinoprostone; Ed

2015
Antiinflammatory and analgesic effects of Eurycoma longifolia extracts.
    Archives of pharmacal research, 2016, Volume: 39, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Cells, Cultured; Cyclooxygenase 2; Diclofena

2016
Low dose aspirin like analgesic and anti-inflammatory activities of mono-hydroxybenzoic acids in stressed rodents.
    Life sciences, 2016, Mar-01, Volume: 148

    Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Edema; Hot Temperature

2016
Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse.
    Journal of thrombosis and haemostasis : JTH, 2016, Volume: 14, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Blood Transfusion; Clopidogrel; Diphtheri

2016
Enhancement of anti-inflammatory property of aspirin in mice by a nano-emulsion preparation.
    International immunopharmacology, 2008, Volume: 8, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Croton Oil; Disease Models, Animal; Drug

2008
Antinociceptive, antiinflammatory and antipyretic properties of Channa striatus fillet aqueous and lipid-based extracts in rats.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:5

    Topics: Amino Acids; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Aspiri

2008
Retropharyngeal edema: an unusual manifestation of Kawasaki disease.
    The Journal of emergency medicine, 2010, Volume: 39, Issue:2

    Topics: Anti-Inflammatory Agents; Aspirin; Child, Preschool; Edema; Humans; Immunoglobulins, Intravenous; Im

2010
Synthesis and pharmacological evaluation of 3-cyclohexyl-2-substituted hydrazino-3H-quinazolin-4-ones as analgesic and anti-inflammatory agents.
    Acta pharmaceutica (Zagreb, Croatia), 2009, Volume: 59, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Diclofenac; Disease Models, Animal; Edema; F

2009
Antinociceptive activity of Amaranthus spinosus in experimental animals.
    Journal of ethnopharmacology, 2009, Apr-21, Volume: 122, Issue:3

    Topics: Acetic Acid; Amaranthus; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carr

2009
Synthesis and analgesic and anti-inflammatory activity of 6-phenyl/(4-methylphenyl)-3(2H)-pyridazinon-2-propionamide derivatives.
    Arzneimittel-Forschung, 2009, Volume: 59, Issue:7

    Topics: Amides; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoqu

2009
Safety of carotid endarterectomy while on clopidogrel (Plavix). Clinical article.
    Journal of neurosurgery, 2010, Volume: 113, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Clopidogrel; Cohort Studies; Edema; E

2010
Therapeutic effect of Linum usitatissimum (flaxseed/linseed) fixed oil on acute and chronic arthritic models in albino rats.
    Inflammopharmacology, 2010, Volume: 18, Issue:3

    Topics: Acute Disease; Alanine Transaminase; Albinism; Animals; Arthritis, Experimental; Aspartate Aminotran

2010
Evaluation of nasal mucosal swelling and microcirculation throughout nasal and bronchial provocation tests with lysine-aspirin in asthmatics with nasal polyposis.
    Rhinology, 2010, Volume: 48, Issue:2

    Topics: Adult; Allergens; Aspirin; Asthma; Bronchial Provocation Tests; Edema; Female; Humans; Laser-Doppler

2010
Clinico-pathologic conference: case 6.
    Head and neck pathology, 2009, Volume: 3, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Carcinoma, Squamous Cell;

2009
Comparison between 3-Nitrooxyphenyl acetylsalicylate (NO-ASA) and O2-(acetylsalicyloxymethyl)-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (NONO-ASA) as safe anti-inflammatory, analgesic, antipyretic, antioxidant prodrugs.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Antipyretics; Aspirin; Dinoprostone;

2010
Lipoxin A(4) attenuates zymosan-induced arthritis by modulating endothelin-1 and its effects.
    British journal of pharmacology, 2010, Volume: 161, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Edema; Endothelin-1; Gene Expre

2010
Analgesic and anti-inflammatory activities of 18-acetoxy-ent-kaur-16-ene from Annona squamosa L. bark.
    Inflammopharmacology, 2011, Volume: 19, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Annona; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diterpen

2011
Anti-inflammatory and gastromucosal protective effects of Calotropis procera (Asclepiadaceae) stem bark.
    Journal of natural medicines, 2011, Volume: 65, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Calotropis; Carrageenan; Chromatography, High Pressure L

2011
Studies on anti-inflammatory and analgesic activities of betel nut in rodents.
    Journal of ethnopharmacology, 2011, Jun-01, Volume: 135, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Areca; Aspirin; Behavior, Animal; Biphe

2011
Nitroxide derivatives of non-steroidal anti-inflammatory drugs exert anti-inflammatory and superoxide dismutase scavenging properties in A459 cells.
    British journal of pharmacology, 2012, Volume: 165, Issue:4b

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Carrageenan; Cell Line, Tum

2012
Inhibitory effects of 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, β-diketone structural analogues of curcumin, on chemical-induced tumor promotion and inflammation in mouse skin.
    Food & function, 2011, Volume: 2, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Aspirin; Carc

2011
In vivo and in vitro anti-inflammatory activity of neorogioltriol, a new diterpene extracted from the red algae Laurencia glandulifera.
    Marine drugs, 2011, Volume: 9, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Cell

2011
Differential inhibitory potencies of alcoholic extract of different parts of Dryopteris chrysocoma on inflammation in mice and rats.
    Pakistan journal of pharmaceutical sciences, 2011, Volume: 24, Issue:4

    Topics: Animals; Aspirin; Carrageenan; Dryopteris; Edema; Ethanol; Female; Formaldehyde; Inflammation; Male;

2011
Aspirin analogues as dual cyclooxygenase-2/5-lipoxygenase inhibitors: synthesis, nitric oxide release, molecular modeling, and biological evaluation as anti-inflammatory agents.
    ChemMedChem, 2012, Jan-02, Volume: 7, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyclooxygenase 2 Inhibitors; Edema; Humans; Lipoxygenase

2012
Biological activity of some derivatives of β-cyclodextrin.
    Bulletin of experimental biology and medicine, 2011, Volume: 151, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; beta-Cyclodextrins; Edema; Ibuprofen; Mice; Molecular St

2011
Unusual manifestations of Kawasaki disease with retropharyngeal edema and shock syndrome in a Taiwanese child.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2014, Volume: 47, Issue:2

    Topics: Aspirin; Cervix Uteri; Child, Preschool; Edema; Exanthema; Female; Fever; Humans; Immunoglobulins, I

2014
Anti-inflammatory and analgesic activity of novel oral aspirin-loaded nanoemulsion and nano multiple emulsion formulations generated using ultrasound cavitation.
    International journal of pharmaceutics, 2012, Jul-01, Volume: 430, Issue:1-2

    Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Behavior,

2012
Evaluation of the in vivo anti-inflammatory and analgesic activity of a highly water-soluble aspirin conjugate.
    Basic & clinical pharmacology & toxicology, 2013, Volume: 112, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Disease Models, Animal; Dose

2013
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cardiotoxins; Clomipramine; Cyclophosphamide; Disease

2014
Antiinflammatory, gastrosparing, and antiplatelet properties of new NO-donor esters of aspirin.
    Journal of medicinal chemistry, 2003, Feb-27, Volume: 46, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Edema; Esters; Gastric Mucosa; Humans; Hy

2003
Anti-inflammatory and anti-nociceptive effects of Sphaeranthus senegalensis.
    Journal of ethnopharmacology, 2003, Volume: 84, Issue:2-3

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asteraceae; Edema;

2003
Antiinflammatory property of 3-aryl-5-(n-propyl)-1,2,4-oxadiazoles and antimicrobial property of 3-aryl-5-(n-propyl)-4,5-dihydro-1,2,4-oxadiazoles: their syntheses and spectroscopic studies.
    Bioorganic & medicinal chemistry, 2003, Apr-17, Volume: 11, Issue:8

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacillus subtilis;

2003
Synthesis of vanillin ethers from 4-(bromomethyl) coumarins as anti-inflammatory agents.
    European journal of medicinal chemistry, 2003, Volume: 38, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzaldehydes; Carrageenan; Coumarins; Ed

2003
Synthesis and anti-inflammatory activity of 5-(6-methyl-2-substituted 4-pyrimidinyloxymethyl)-1,3,4-oxadiazole-2-thiones and their 3-morpholinomethyl derivatives.
    Farmaco (Societa chimica italiana : 1989), 2003, Volume: 58, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bentonite; Carrageenan; Edema; Female; Hi

2003
Studies on novel 7-acyl-5-chloro-2-oxo-3H-benzoxazole derivatives as potential analgesic and anti-inflammatory agents.
    Archiv der Pharmazie, 2003, Volume: 336, Issue:6-7

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoxazoles; Capillary Perme

2003
Antiinflammatory and antiulcer activities of Bambusa arundinacea.
    Journal of ethnopharmacology, 2003, Volume: 88, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Bambusa; Carrageenan;

2003
[Rat paw edema and its relationship to other inflammatory test substances. (Comparison of phenylbutazone with 2-aminoquinoxaline)].
    Helvetica physiologica et pharmacologica acta, 1963, Volume: 21

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Aspirin; Edema; Kaolin; Phenylbutazone;

1963
RADIOMETRIC QUANTITATION OF THE INHIBITION OF 5-HYDROXYTRYPTAMINE- INDUCED EDEMA IN MICE.
    Archives internationales de pharmacodynamie et de therapie, 1963, Jul-01, Volume: 144

    Topics: Animals; Ascorbic Acid; Aspirin; Cyproheptadine; Edema; Flavonoids; Inflammation; Mice; Phenylbutazo

1963
ANTI-INFLAMMATORY AND ANTIPYRETIC ACTIVITIES OF INDOMETHACIN, 1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 141

    Topics: Acetates; Adrenalectomy; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents

1963
EFFECTS OF ACETYLSALICYLIC ACID ON THE EDEMA AND HYPERESTHESIA OF THE EXPERIMENTALLY INFLAMED RAT'S PAW.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 142

    Topics: Aspirin; Edema; Hyperesthesia; Inflammation; Leg; Pharmacology; Rats; Research; Saccharomyces

1963
[ATTEMPTED INHIBITION OF BRADYKININ-INDUCED EDEMA IN RATS].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Dec-15, Volume: 157

    Topics: Adrenocorticotropic Hormone; Aldosterone; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Ascorb

1963
[KAOLIN- AND ACETYLSALICYLIC ACID-INDUCED EDEMA IN THE CANCEROUS RAT].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Oct-05, Volume: 157

    Topics: Aspirin; Drug Hypersensitivity; Edema; Kaolin; Neoplasms; Neoplasms, Experimental; Pharmacology; Rat

1963
ANTIINFLAMMATORY POTENCY OF 2-(BETA-CHLOROETHYL)-2,3-DIHYDRO-4-OXO-6-AMINO-(BENZ-1,3-OXAZINE) HCL(A350), PHENYLBUTAZONE AND ACETYLSALICYLIC ACID IN CARRAGEENIN-INDUCED EDEMA.
    Medicina experimentalis : International journal of experimental medicine, 1964, Volume: 10

    Topics: Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Inflammation; Leg; Oxazines; Pharmacology; Ph

1964
EXPERIMENTAL EVALUATION IN LABORATORY ANIMALS OF ANTI-INFLAMMATORY ANALGESIC DRUGS.
    Archives italiennes de biologie, 1963, Oct-05, Volume: 101

    Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Animals; Animals, Laboratory; Anti-Inflammatory A

1963
THE EFFECT OF SALURETICS ON PULSE RATE, BLOOD PRESSURE AND ELECTROCARDIOGRAM DURING EXERCISE IN NORMAL SUBJECTS.
    Acta medica Scandinavica, 1964, Volume: 175

    Topics: Aspirin; Biomedical Research; Blood; Blood Pressure; Blood Pressure Determination; Chlorides; Chlort

1964
[DRUG ALLERGY IN PATIENTS SUFFERING FROM ALLERGIC DISEASES WITH IMMEDIATE REACTION].
    Acta allergologica, 1964, Volume: 19

    Topics: Anaphylaxis; Anti-Bacterial Agents; Aspirin; Asthma; Barbiturates; Codeine; Drug Eruptions; Drug Hyp

1964
EFFECT OF ANTI-INFLAMMATORY AGENTS ON CAPILLARY PERMEABILITY AND OEDEMA FORMATION.
    Nature, 1964, May-23, Volume: 202

    Topics: Ammonium Compounds; Animals; Anti-Inflammatory Agents; Aspirin; Capillary Permeability; Chlorpromazi

1964
[NON-STEROID ANTI-INFLAMMATORY AGENTS. I. DERIVATIVES OF 4- AND 5-AMINOSALICYLIC ACIDS].
    Medicina experimentalis : International journal of experimental medicine, 1964, Volume: 11

    Topics: 4-Aminobenzoic Acid; Aminopyrine; Aminosalicylic Acid; Aminosalicylic Acids; Analgesics; Analgesics,

1964
[COMPARATIVE ANTIPHLOGISTIC ACTIVITY OF DERIVATIVES OF ANTIMALARIALS].
    Archivio italiano di scienze farmacologiche, 1963, Volume: 13

    Topics: Aminopyrine; Anti-Inflammatory Agents; Antimalarials; Aspirin; Edema; Inflammation; Mice; Pharmacolo

1963
[Sudden edema and pain in the knee].
    Duodecim; laaketieteellinen aikakauskirja, 2003, Volume: 119, Issue:17

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Artery Disease; Drug Interactio

2003
Anti-inflammatory action of sulfoaryl 3,3-disubstituted triazenes in rat experimental edema models.
    Die Pharmazie, 2003, Volume: 58, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bentonite; Carrageenan; Chemical Phenomen

2003
Amide derivatives of [6-(5-methyl-3-phenylpyrazole-1-yl)-3(2H)-pyridazinone-2-yl]acetic acids as potential analgesic and anti-inflammatory compounds.
    Archiv der Pharmazie, 2004, Volume: 337, Issue:1

    Topics: Acetates; Administration, Oral; Amides; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal

2004
Effects of various analgesics on inflammatory edema resulting from silver nitrate injection.
    Science (New York, N.Y.), 1951, Aug-17, Volume: 114, Issue:2955

    Topics: Analgesics; Aspirin; Edema; Humans; Inflammation; Injections; Silver Nitrate

1951
Synthesis, characterization and antiinflammatory-analgesic properties of 6-(alpha-amino-4-chlorobenzyl)thiazolo [3,2-b]-1,2,4-triazol-5-ols.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:1

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Capillary Per

2004
Gastric effects of the selective cyclooxygenase-2 inhibitor, celecoxib, in the rat.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:4

    Topics: Animals; Aspirin; Carrageenan; Celecoxib; Consciousness; Cyclooxygenase Inhibitors; Edema; Gastric M

2004
Isolation of a haemorrhagic protein toxin (SA-HT) from the Indian venomous butterfish (Scatophagus argus, Linn) sting extract.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:5

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non

2004
[Periorbital swelling caused by carbasalate calcium].
    Nederlands tijdschrift voor geneeskunde, 2004, Jul-31, Volume: 148, Issue:31

    Topics: Aspirin; Diagnosis, Differential; Edema; Eyelid Diseases; Eyelids; Humans; Male; Middle Aged; Platel

2004
New xanthone derivatives as potent anti-inflammatory agents.
    Medicina (Kaunas, Lithuania), 2005, Volume: 41, Issue:1

    Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrage

2005
Differential impact of prostaglandin H synthase 1 knockdown on platelets and parturition.
    The Journal of clinical investigation, 2005, Volume: 115, Issue:4

    Topics: Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cyclooxygenase 1; Edema; Estradiol; Female; Hum

2005
Stereoselective synthesis and anti-inflammatory activities of 6- and 7-membered dioxacycloalkanes.
    Bioorganic & medicinal chemistry, 2006, Mar-01, Volume: 14, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cycloparaffins; Ear Diseases; Edema; Mice

2006
Synthesis of beta-hydroxypropanoic acid derivatives as potential anti-inflammatory, analgesic and antimicrobial agents.
    Archiv der Pharmazie, 2006, Volume: 339, Issue:7

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antifungal Agents; Aspergillus

2006
Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin.
    Prostaglandins & other lipid mediators, 2006, Volume: 80, Issue:3-4

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bradykinin; Carrageenan; D

2006
Synthesis and pharmacological evaluation of some 3-(4-methylphenyl)-2-substituted amino-3H-quinazolin-4-ones as analgesic and anti-inflammatory agents.
    Archiv der Pharmazie, 2007, Volume: 340, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Diclofenac; Disease Models, Ani

2007
Dermacase. Chronic venous insufficiency.
    Canadian family physician Medecin de famille canadien, 2006, Volume: 52, Issue:10

    Topics: Aged; Aspirin; Chronic Disease; Edema; Fibrinolytic Agents; Humans; Leg; Male; Stockings, Compressio

2006
Analgesic and anti-inflammatory activities of a fraction rich in gaultherin isolated from Gaultheria yunnanensis (FRANCH.) REHDER.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Croton

2007
Synthesis and pharmacological investigation of novel 3-(3-methylphenyl)-2-substituted amino-3H-quinazolin-4-ones as analgesic and anti-inflammatory agents.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Diclofenac; Disease Models, Ani

2007
Flavonoids with anti-inflammatory and antinociceptive activity from Cistus laurifolius L. leaves through bioassay-guided procedures.
    Journal of ethnopharmacology, 2007, Jul-25, Volume: 112, Issue:3

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Biological Assay; Carrageenan;

2007
[Experimental research on anti-inflammatory effects of Fu' an oral liquid].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2007, Volume: 30, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capillary Permeabil

2007
Triterpenoid saponins and anti-inflammatory activity of Codonopsis lanceolata.
    Die Pharmazie, 2007, Volume: 62, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carbohydrate Sequence; Carrageenan; Codonopsis; Edema; H

2007
Assessment of anti-inflammatory and antinociceptive activities of Daphne pontica L. (Thymelaeaceae).
    Journal of ethnopharmacology, 2007, Sep-05, Volume: 113, Issue:2

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzoquinones; Carrageenan; Colic;

2007
Hyperbaric oxygen treatment is comparable to acetylsalicylic acid treatment in an animal model of arthritis.
    The journal of pain, 2007, Volume: 8, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Behavior, Animal; Carrageenan;

2007
Presence of a general irritation and inhibition of a local inflammation.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 14, Issue:5

    Topics: Acetates; Animals; Aspirin; Blood; Carrageenan; Coloring Agents; Edema; Female; Formaldehyde; Hypert

1966
The pharmacology of 2,3-bis-(p-methoxyphenyl)-indole (indoxole).
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:1

    Topics: Adrenalectomy; Anaphylaxis; Animals; Arthritis; Arthritis, Rheumatoid; Aspirin; Barbiturates; Edema;

1967
[Antipyretic, antiedematous and analgetic effects of damascenin in comparison with acetylsalicylic acid and phenylbutazone].
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 168, Issue:1

    Topics: Alkaloids; Animals; Aspirin; Behavior, Animal; Body Temperature; Edema; Formaldehyde; Furosemide; Gu

1967
Bradykinin and oedema formation in heated paws of rats.
    British journal of pharmacology and chemotherapy, 1967, Volume: 31, Issue:1

    Topics: Animals; Aspirin; Bradykinin; Edema; Flufenamic Acid; Guinea Pigs; Histamine Release; Hot Temperatur

1967
Comparison of the action of antiphlogistics, anti-anaphylactics and antihistaminics in the carrageenin- & immunologically-induced inflammation model in the rat and in passive cutaneous anaphylaxis.
    Agents and actions. Supplements, 1982, Volume: 10

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Disease Models, Animal; Edema; Female; Hist

1982
Effect of central prostaglandins on carrageenan-induced pedal oedema in rats.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:11

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Carrageenan; Diclofenac; Dinoprost; Dinoprost

1984
[Interaction of polymorphonuclear leukocytes, bradykinin and carragenin. Transference reaction in the rat].
    Archives internationales de physiologie et de biochimie, 1982, Volume: 90, Issue:3

    Topics: Animals; Aspirin; Bradykinin; Carrageenan; Drug Synergism; Edema; Indomethacin; Neutrophils; Phospho

1982
Anti-inflammatory activity of Eryngium maritimum L. rhizome extracts in intact rats.
    Journal of ethnopharmacology, 1984, Volume: 12, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Female; Foot; Granuloma; Hydrocortis

1984
Butyl hydroxy toluene antagonizes the gastric toxicity but not the pharmacological activity of acetylsalicylic acid in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 325, Issue:3

    Topics: Analgesia; Animals; Aspirin; Butylated Hydroxytoluene; Carrageenan; Edema; Fever; Male; Rats; Rats,

1984
Blockade of the inflammatory effects of platelet-activating factor by cyclo-oxygenase inhibitors.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1981, Volume: 14, Issue:2-3

    Topics: Animals; Aspirin; Carrageenan; Cyclooxygenase Inhibitors; Edema; Hyperalgesia; Indomethacin; Lysopho

1981
Preclinical studies on indoprofen, a new non-steroidal analgesic-antiinflammatory agent.
    European journal of rheumatology and inflammation, 1981, Volume: 4, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Do

1981
Therapeutic and adjunctive applications of an imidazoline anti-inflammatory agent.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Aspirin; Carrageenan; Clonidine; Drug Therapy,

1983
Pharmacological studies in the rat with [2-(1,3-didecanoyloxy)-propyl]2-acetyloxybenzoate (A-45474): an aspirin pro-drug with negligible gastric irritation.
    Agents and actions, 1980, Volume: 10, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; As

1980
Gastric ulcerogenic and biological activities of N-3'a-propyphenazonyl-2-acetoxybenzamide.
    Chemical & pharmaceutical bulletin, 1980, Volume: 28, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine;

1980
[Pharmacological and biochemical study of a new non-narcotic analgesic: fosfosal (UR-1521)].
    Archivos de farmacologia y toxicologia, 1981, Volume: 7, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capillary Permeability; Cattle; Edema; Fe

1981
[Comparison of the effect of 3-amino-4-mercapto-6-methylpyridazine with various antiphlogistic agents in rat models of inflammation].
    Die Pharmazie, 1982, Volume: 37, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Di

1982
[The mucocutaneous lymph node syndrome (Kawasaki syndrome). A case with gallbladder hydrops and coronary artery aneurysm].
    Schweizerische medizinische Wochenschrift, 1981, Apr-18, Volume: 111, Issue:16

    Topics: Aneurysm; Aspirin; Child, Preschool; Coronary Disease; Edema; Erythromycin; Exanthema; Gallbladder D

1981
Interaction of indomethacin and aspirin or mepirizole in rats as shown by gastrointestinal ulcerogenic and anti-inflammatory activities.
    Journal of pharmacobio-dynamics, 1980, Volume: 3, Issue:12

    Topics: Animals; Aspirin; Biological Transport; Charcoal; Drug Interactions; Edema; Epirizole; Indomethacin;

1980
Anti-inflammatory testing methods: comparative evaluation of mice and rats.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Cyproheptadine; Edema; Female;

1981
Blockade by antiglucocorticoids, actinomycin D and cycloheximide of anti-inflammatory action of dexamethasone against bradykinin.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 212, Issue:2

    Topics: Androstenedione; Animals; Aspirin; Bradykinin; Cell Membrane Permeability; Cycloheximide; Dactinomyc

1980
Kawasaki disease, or mucocutaneous lymph node syndrome: report of seven cases in North America.
    Canadian Medical Association journal, 1980, May-10, Volume: 122, Issue:9

    Topics: Aspirin; Child; Child, Preschool; Coronary Disease; Diagnosis, Differential; Edema; Female; Gallblad

1980
Biochemical gastroprotection from acute ulceration induced by aspirin and related drugs.
    Biochemical pharmacology, 1980, May-01, Volume: 29, Issue:9

    Topics: Amino Acids; Animals; Aspirin; Buffers; Carrageenan; Edema; Female; Glucose; Male; Rats; Stomach Ulc

1980
Anti-inflammatory properties of cannabichromene.
    Life sciences, 1980, Jun-09, Volume: 26, Issue:23

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Benzopyrans; Cannabinoids; Edema; Erythrocyte Membrane;

1980
Pharmacokinetics and pharmacodynamics in copper deficiency. I. Antiinflammatory activity of aspirin.
    Biological trace element research, 1994, Volume: 40, Issue:2

    Topics: Analysis of Variance; Animals; Aspirin; Carboxylic Ester Hydrolases; Chromatography, High Pressure L

1994
3-substituted piperazinomethyl benzoxazolinones. Analgesic and anti-inflammatory compounds inhibiting prostaglandin E2.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoxazoles; Carrageenan; Edema; Female;

1995
Synthesis and antiinflammatory, analgesic, and antipyretic testing of 4-[1-oxo-(3-substituted aryl)-2-propenyl]-3-phenylsydnones and of 3-[4-[3-(substituted aryl)-1-oxo-2-propenyl]phenyl]sydnones.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; As

1995
Dual inhibition of platelet-activating factor and arachidonic acid metabolism by ajmaline and effect on carrageenan-induced rat paw oedema.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:8

    Topics: Ajmaline; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Carbon Radioisotopes; Carrageenan; Ed

1993
Involvement of leukotrienes in allergic inflammation in mice.
    European journal of pharmacology, 1994, May-23, Volume: 257, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; A

1994
Preliminary screening of methanolic extracts of Celastrus paniculatus and Tecomella undulata for analgesic and anti-inflammatory activities.
    Journal of ethnopharmacology, 1994, Volume: 42, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Edema; Female; Male; Methanol; Mice; Plant E

1994
Synthesis and anti-inflammatory properties of 1,2-dialkoxy-4-(3-dimethylaminopropionyl)benzenes and their 5-halogeno derivatives.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Edema; Foot Inju

1994
Antinociceptive, anti-inflammatory and antipyretic effects of lapidin, a bicyclic sesquiterpene.
    Planta medica, 1994, Volume: 60, Issue:5

    Topics: Analgesics; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-S

1994
Triterpenes and B-sitosterol from piper betle: isolation, antiplatelet and anti-inflammatory effects.
    Biochemical Society transactions, 1993, Volume: 21, Issue:4

    Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Areca; As

1993
Synthesis and some properties of two salsalate derivatives.
    Farmaco (Societa chimica italiana : 1989), 1993, Volume: 48, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Antitussive Agents; Aspirin; Chromat

1993
Effect of KBT-3022, a new diphenylthiazole derivative, on platelet functions.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:9

    Topics: Adenosine Diphosphate; Administration, Oral; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Co

1995
Aspirin increases tissue oedema after skeletal muscle ischaemia and reperfusion.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 1996, Volume: 12, Issue:1

    Topics: Administration, Oral; Animals; Aspirin; Cell Movement; Disease Models, Animal; Edema; Hindlimb; Infu

1996
Anti-inflammatory and anti-nociceptive activity of disodium glycyrrhetinic acid hemiphthalate.
    Planta medica, 1996, Volume: 62, Issue:4

    Topics: Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Edema;

1996
The bee venom test: a new tonic-pain test.
    Pain, 1996, Volume: 66, Issue:2-3

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Aspirin; Bee Venoms; Behavior, Animal; Edema;

1996
Anti-inflammatory effects of beraprost sodium, a stable analogue of PGI2, and its mechanisms.
    Prostaglandins, 1997, Volume: 53, Issue:4

    Topics: Alprostadil; Animals; Anti-Inflammatory Agents; Aspirin; Cell Membrane Permeability; Collagen; Dose-

1997
A comparative study of the analgesic and anti-inflammatory activities of pectolinarin isolated from Cirsium subcoriaceum and linarin isolated from Buddleia cordata.
    Planta medica, 1998, Volume: 64, Issue:2

    Topics: Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromon

1998
Anti-inflammatory activity of the alkaloid bukittinggine from Sapium baccatum.
    Planta medica, 1998, Volume: 64, Issue:6

    Topics: Abdominal Muscles; Acetic Acid; Alkaloids; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agen

1998
[Analgesic and anti-inflammatory activity of saponins of Argania spinoza].
    Annales pharmaceutiques francaises, 1998, Volume: 56, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Edema; Indomethacin; Mice; Pa

1998
Cyclooxygenase-2 selective and nitric oxide-releasing nonsteroidal anti-inflammatory drugs and gastric mucosal responses.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1998, Volume: 49, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Cyclooxygenase 2; Dinoprosto

1998
A comparison of the anti-inflammatory and anti-nociceptive activity of nitroaspirin and aspirin.
    British journal of pharmacology, 2000, Volume: 129, Issue:2

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ca

2000
Antinociceptive and anti-oedematogenic properties of astilbin, taxifolin and some related compounds.
    Arzneimittel-Forschung, 2000, Volume: 50, Issue:3

    Topics: Acetaminophen; Acetates; Analgesics; Analgesics, Non-Narcotic; Animals; Aspirin; Edema; Flavonoids;

2000
Cases from the aerospace medicine residents' teaching file. Decompression sickness.
    Aviation, space, and environmental medicine, 2000, Volume: 71, Issue:12

    Topics: Adult; Aerospace Medicine; Aspirin; Decompression Sickness; Diagnosis, Differential; Diving; Edema;

2000
Anti-inflammatory and analgesic activity of Indian Hypericum perforatum L.
    Indian journal of experimental biology, 2001, Volume: 39, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Edema; Female; Granuloma, For

2001
Gastric mucus effusion elicited by oral copper compounds: potential anti-ulcer activity.
    Experientia, 1976, Sep-15, Volume: 32, Issue:9

    Topics: Administration, Oral; Animals; Aspirin; Copper; Edema; Female; Foot; Gastric Mucosa; Hindlimb; Hydro

1976
The role of copper in preventing gastrointestinal damage by acidic anti-inflammatory drugs.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:12

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chelating Agents; Copper; Edema

1976
Acute anti-inflammatory effects of aspirin and dexamethasone in rats deprived of endogenous prostaglandin precursors.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Dexamethasone; Diet; Edema; Fatty Acids; Fa

1977
Pharmacological properties of 2,3-dihydro-9H-isoxazolo [3,2-b] quinazolin-9-one (W-2429. Part 1: Analgesic, antipyretic and antiedema activity.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:4

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthriti

1977
[Role of platelets in arterial hypotension induced by arachidonic acid and in carrageenan induced edema in the rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1979, Volume: 173, Issue:4

    Topics: Arachidonic Acids; Aspirin; Blood Platelets; Carrageenan; Edema; Hypotension; Kinetics; Malondialdeh

1979
Central and peripheral antialgesic action of aspirin-like drugs.
    European journal of pharmacology, 1978, Dec-15, Volume: 53, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Drug Interaction

1978
Studies on the effects of anti-inflammatory action of benzoyl-hydrotropic acid (ketoprofen) and other drugs, with special reference to prostaglandin synthesis.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 237, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Foot; Indomethacin; Ketoprofen; Male

1979
Aspirin, salicylate and prostaglandins.
    Agents and actions, 1979, Volume: 9, Issue:5-6

    Topics: Animals; Arachidonic Acids; Aspirin; Carrageenan; Edema; Exudates and Transudates; Female; Gentisate

1979
Synthesis and anti-inflammatory properties of some pyrrolo(1H,3H)[3,4-d]pyrimidin-2-ones and pyrrolo(1H,6H)[3,4-d]pyrimidin-2-ones.
    Il Farmaco; edizione scientifica, 1979, Volume: 34, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Edema; Female; Indomethacin; Ma

1979
[Pharmacological studies of 2-(5H-(1)benzopyrano[2,3-b]pyridin-7-yl)propionic acid (Y-8004). (3) Its interaction with anti-inflammatory agents].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Dose-Response Relationship, Dru

1977
Environmental stress and aspirin.
    Proceedings of the Royal Society of Medicine, 1977, Volume: 70 Suppl 7

    Topics: Adult; Aspirin; Edema; Erythema; Humans; Prostaglandins; Stress, Physiological

1977
Comparative antiphlogistic activity of meseclazone, 5-chlorosalicylic acid, acetylsalicylic acid, phenylbutazone, indomethacin and hydrocortisone in various rat paw edema models.
    Pharmacology, 1978, Volume: 16, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Benzoxazines; Drug Evaluation, Preclinical; Edema; Hydro

1978
A new mechanical method for measuring rat paw edema.
    Pharmacology, 1978, Volume: 16, Issue:3

    Topics: Animals; Aspirin; Carrageenan; Disease Models, Animal; Edema; Male; Methods; Rats

1978
Interaction of sudoxicam and aspirin in animals and man.
    Clinical pharmacology and therapeutics, 1975, Volume: 18, Issue:4

    Topics: Animals; Arthritis, Rheumatoid; Aspirin; Depression, Chemical; Drug Interactions; Edema; Half-Life;

1975
The significance of inhibition of prostaglandin synthesis in the selection of non-steroidal anti-inflammatory agents.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Analgesia; Animals; Anti-Inflammatory Agents; Aspirin; Body Temperature; Cyclooxygenase Inhibitors;

1975
Non-steroid anti-inflammatory drugs: combined assay for anti-edemic potency and gastric ulcerogenesis in the same animal.
    Life sciences, 1977, Aug-01, Volume: 21, Issue:3

    Topics: Acacia; Adjuvants, Pharmaceutic; Animals; Aspartic Acid; Aspirin; Carrageenan; Diclofenac; Drug Eval

1977
[Characterization of the sodium nucleinate-edema of the rat paw].
    Die Pharmazie, 1977, Jun-06, Volume: 32, Issue:6

    Topics: Animals; Aspirin; Dextrans; Disease Models, Animal; Edema; Escin; Nucleic Acids; Ovalbumin; Phenylbu

1977
Some aspects of the pharmacology of butibufen, a non-steroidal anti-inflammatory agent.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 227, Issue:1

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Edema; Gr

1977
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration.
    Agents and actions, 1976, Volume: 6, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen

1976
Synthesis and antiinflammatory activity of some 1,6-methano[10]annuleneacetic acids.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:6

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bridg

1975
Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:11

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Cap

1975
[Experimental studies on the possibility of influencing mast cells in experimental carrageenin-induced rat paw edema. Histological study on the effects of some non-steroidal anti-inflammatory agents (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Cell Count; Edema; Indometha

1976
Conjunctival temperature: a measure of ocular decongestant and anti-inflammatory activity.
    Annals of ophthalmology, 1975, Volume: 7, Issue:6

    Topics: Administration, Oral; Administration, Topical; Animals; Antazoline; Anti-Inflammatory Agents; Aspiri

1975
Floctafenine, a new non-narcotic analgesic.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 216, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Dextropropoxyphene; D

1975
Anti-inflammatory action of an s-triazine derivative in rats.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:2

    Topics: Administration, Topical; Adrenalectomy; Aniline Compounds; Animals; Anti-Inflammatory Agents; Arthri

1975
Chemistry and pharmacology of naproxen.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:2A

    Topics: Administration, Oral; Adrenalectomy; Animals; Aspirin; Carrageenan; Drug Evaluation, Preclinical; Ed

1975
Biological properties of a new non-steroidal anti-inflammatory drug: etoclofene.
    Il Farmaco; edizione scientifica, 1975, Volume: 30, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Edema; Female; Guinea Pigs; Indom

1975
Characteristic features of actinomycin D-induced paw inflammation of the rat.
    Experimental and molecular pathology, 1975, Volume: 23, Issue:3

    Topics: Acid Phosphatase; Animals; Aspirin; Capillary Permeability; Dactinomycin; Dose-Response Relationship

1975
The activity of suprofen on nystatin-induced paw oedema in rats.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dose-Response Relationship, Drug; Drug Evaluation, Precl

1975
Comparison of kinin-forming and amidolytic activities of four trimucases, oedema-producing and kinin-releasing enzymes, from Trimeresurus mucrosquamatus venom.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:4

    Topics: Amides; Animals; Aspirin; Crotalid Venoms; Diphenhydramine; Edema; Ileum; Kinins; Methysergide; Musc

1992
Interaction studies of tilomisole, aspirin, and naproxen in acute and chronic inflammation with assessment of gastrointestinal irritancy in the rat.
    Agents and actions, 1992, Volume: 36, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Benzimidazoles;

1992
[Suppressive effect of sialic acid on the prostaglandin E2-mediated edema in carrageenin-induced inflammation of rat hind paws].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 99, Issue:5

    Topics: Animals; Aspirin; Carrageenan; Dinoprostone; Edema; Guinea Pigs; Injections, Subcutaneous; Male; N-A

1992
Reduction of aspirin-induced gastric damage in rats by interleukin-1 beta: possible involvement of endogenous corticosteroids.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:3

    Topics: Adrenalectomy; Animals; Aspirin; Dexamethasone; Dinoprostone; Edema; Epoprostenol; Gastric Acid; Gas

1992
Effect of PAF-acether antagonists on active anaphylactic mouse paw edema.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; A

1991
Effects of anti-inflammatory drugs on rat hind-paw swelling caused by phospholipase A2 from Naja naja atra venom.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal

1991
Cu(II) complex of an estradiol derivative with potent anti-inflammatory properties.
    Archiv der Pharmazie, 1991, Volume: 324, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Copper; Edema; Estradiol; Male; Organometal

1991
Treatment of severe pre-eclampsia by acetyl salicylic acid.
    Asia-Oceania journal of obstetrics and gynaecology, 1991, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Albuminuria; Aspirin; Blood Pressure; Body Temperature; Edema; Female; Humans; Hy

1991
Prostaglandin (PG) modulation of bradykinin-induced hyperalgesia and oedema in the guinea-pig paw--effects of PGD2, PGE2 and PGI2.
    Agents and actions. Supplements, 1991, Volume: 32

    Topics: Animals; Aspirin; Bradykinin; Dinoprostone; Edema; Epoprostenol; Female; Guinea Pigs; Pain; Prostagl

1991
Effect of zinc acexamate on gastric lesions induced by aspirin: a morphological study.
    European journal of pharmacology, 1990, Nov-06, Volume: 190, Issue:1-2

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Anti-Ulcer Agents; Aspirin; Carrageenan; Chromatography,

1990
Evaluation of combined systemic aspirin and cromolyn sodium in intractable vernal catarrh.
    Annals of ophthalmology, 1990, Volume: 22, Issue:8

    Topics: Adolescent; Adult; Aspirin; Chi-Square Distribution; Child; Conjunctivitis, Allergic; Cromolyn Sodiu

1990
Studies on non-steroidal anti-inflammatory and related biological activities of 5-(indan-1'-yl)tetrazoles and their intermediates.
    Indian journal of physiology and pharmacology, 1990, Volume: 34, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Carrageenan; Ede

1990
Research on heterocyclic compounds. XXVI. Antiinflammatory and related activities of some 2-phenylimidazo[1,2-b]pyridazines.
    Research communications in chemical pathology and pharmacology, 1990, Volume: 67, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Carrageenan;

1990
Mode of analgesic action of dipyrone: direct antagonism of inflammatory hyperalgesia.
    European journal of pharmacology, 1985, Aug-27, Volume: 114, Issue:3

    Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Bucladesine; Carrageenan; Dinoprostone; Di

1985
On steroid-saving drug combinations in carrageenin paw edema and adjuvant arthritis.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:10

    Topics: Animals; Arthritis; Arthritis, Experimental; Aspirin; Carrageenan; Cyclooxygenase Inhibitors; Dexame

1986
Salicylates inhibit PAF-acether-induced rat paw oedema when cyclooxygenase inhibitors are ineffective.
    Prostaglandins, 1986, Volume: 32, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Aspirin; Cyclooxygenas

1986
Effects of paracetamol and acetylsalicylic acid on the post-operative course after experimental orthopaedic surgery in dogs.
    Journal of veterinary pharmacology and therapeutics, 1988, Volume: 11, Issue:2

    Topics: Acetaminophen; Animals; Aspirin; Dogs; Edema; Female; Forelimb; Inflammation; Male; Pain, Postoperat

1988
Antiinflammatory activities of copper-aspirinate and aspirin in adjuvant arthritic rats.
    Research communications in chemical pathology and pharmacology, 1988, Volume: 60, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experi

1988
Pharmacological activity of FPP028 (2-phenylpyrazolo-4-ethyl-4,7-dihydro [1,5a]pyrimidin-7-one) a new non-steroid anti-inflammatory agent.
    Pharmacological research communications, 1986, Volume: 18, Issue:3

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin;

1986
Interactions between local inflammatory and systemic haematological effects of PAF-acether in the rat.
    European journal of pharmacology, 1987, Apr-29, Volume: 136, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Edema; Indomethacin; Inflammation; Male;

1987
Salicylate antagonizes the antiinflammatory action of aspirin in the rat.
    Prostaglandins, leukotrienes, and medicine, 1985, Volume: 20, Issue:1

    Topics: Animals; Aspirin; Carrageenan; Drug Antagonism; Edema; Kinetics; Male; Rats; Salicylates; Salicylic

1985
Analgesic, anti-inflammatory and oxy-radical scavenger activity of imidazole and imidazole derivatives.
    International journal of tissue reactions, 1985, Volume: 7, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Edema; Gastritis

1985
The effects of some benzoic acid derivatives on polymorphonuclear leukocyte accumulation in vivo.
    International journal of immunopharmacology, 1985, Volume: 7, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Benzoates; Edema; Epoprostenol; Male; Neutrophils; Rats;

1985
Sorbic acid-induced erythema and edema.
    Journal of the American Academy of Dermatology, 1986, Volume: 14, Issue:2 Pt 1

    Topics: Administration, Topical; Anti-Inflammatory Agents; Aspirin; Betamethasone Valerate; Capsaicin; Cosme

1986
Comparison of the concentration-effect relationship of a local antiinflammatory agent and oral acetylsalicylic acid: the value of local application.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:10

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Dose-Response Relationship, Dru

1985
Gastric mucosal damage induced by non-steroid anti-inflammatory agents in rats of different ages.
    Pharmacology, 1972, Volume: 8, Issue:4

    Topics: Age Factors; Animals; Anti-Inflammatory Agents; Aspirin; Body Weight; Dose-Response Relationship, Dr

1972
Pharmacological analysis of the acute inflammatory process induced in the rat's paw by local injection of carrageenin and by heating.
    British journal of pharmacology, 1973, Volume: 48, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Burns; Carrageenan; Edema; Histamine H1 Antagonists; Ind

1973
[Comparative anti-inflammatory action of anticoagulant substances. Mode of action of phenylindanedione].
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1965, Volume: 13, Issue:3

    Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Carrageenan; Coumarins;

1965
Role of histamine and related substances in development of tolerance to edemagenic gases.
    Toxicology and applied pharmacology, 1965, Volume: 7, Issue:5

    Topics: Animals; Aspirin; Chemical Phenomena; Chemistry; Drug Tolerance; Edema; Female; Histamine; Histamine

1965
[Anti-inflammatory principle synthesized by a strain of Serratia sp].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1969, May-20, Volume: 65, Issue:3

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Bromelains; Carrageenan; Chymotrypsin; Ed

1969
The role of fibrin in the inflammatory response to carrageenin.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 159, Issue:1

    Topics: Animals; Aspirin; Blood Coagulation; Carrageenan; Edema; Fibrin; Fibrinolysin; Heparin; Indenes; Mal

1968
[Relationship between the inhibition of ATPase activity and inflammatory edema by nonsteroid anti-inflammatory drugs. Approach to the screening test in vitro of nonsteroid anti-inflammatory drugs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1970, Jul-20, Volume: 66, Issue:4

    Topics: Acetanilides; Adenosine Triphosphatases; Aminocaproates; Aminopyrine; Aminosalicylic Acids; Animals;

1970
Isolation of the anti-inflammatory principles from Achillea millefolium (Compositae).
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:8

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents; Aspirin; Chromatography; Colorimetry

1969
[Efficacy of different antiphlogistic agents with respect to carrageenan-inflammation, compared with other models of inflammation].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:1

    Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; D

1971
Pharmacological actions of a novel O-acetylsalicylic acid composition.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:12

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arylsulfonates; Aspirin; Cats; Dogs; Drug E

1973
Interaction of aspirin with nonsteroidal anti-inflammatory drugs in rats.
    The Journal of pharmacy and pharmacology, 1968, Volume: 20, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Drug Antagonism; Edema; Indomethacin; Male;

1968
Pharmacological studies of a new antiinflammatory compound, 2-phenyl-6-dimethylamino-6H-cycloheptoxazole.
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:10

    Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Carrageenan; Chloro

1968
The time course of the carrageenan-induced oedema of the paw of the rat.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:9

    Topics: Animals; Aprotinin; Aspirin; Carrageenan; Edema; Foot; Histamine H1 Antagonists; Lysergic Acid Dieth

1970
[Pharmacological studies on clonixin. 1. Anti-inflammatory and analgesic actions and effects on the gastrointestinal tract].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 46, Issue:5

    Topics: Acetylcholine; Aminopyrine; Analgesics; Aniline Compounds; Animals; Anti-Inflammatory Agents; Aspiri

1971
Anti-inflammatory properties of 4,5-diphenyl-2-oxazolepropionic acid (oxaprozin).
    Agents and actions, 1974, Volume: 4, Issue:3

    Topics: Airway Obstruction; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; B

1974
Carrageenin hyperthermia in rats.
    Experientia, 1974, Nov-15, Volume: 30, Issue:11

    Topics: Animals; Aspirin; Body Temperature; Carrageenan; Dose-Response Relationship, Drug; Edema; Female; Fe

1974
Experimental antiinflammatory and analgesic studies with 3-trifluoromethyl-s-triazolo (3,4-a)-isoquinoline.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:2

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Digestive System; Edema

1974
Local anti-inflammatory properties of etoclofene. A new fenamate derivative.
    Pharmacology, 1974, Volume: 11, Issue:4

    Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Benzyl Co

1974
[Pharmacological study of phthalazino-(2,3-b)-phthalazine-5 (14H), 12(7H)-dione (L-5418)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:3

    Topics: Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Barbiturates; Blood Co

1974
Antiinflammatory activity and other pharmacological properties of phthalazino(2,3-b)phthalazine-5,12(7H, 14H)-dione (Diftalone).
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Pressure; Diuresis; Drug Ev

1974
Effects of anti-inflammatory drugs on prostaglandin biosynthesis.
    Nature: New biology, 1972, Jul-26, Volume: 238, Issue:82

    Topics: Acetaminophen; Aldosterone; Animals; Anti-Inflammatory Agents; Aspirin; Azathioprine; Benzoates; Bio

1972
[Harmful effects of common drugs on the visual apparatus. Minor analgesics, antipyretics, nonsteroid anti-inflammatory and antirheumatic drugs].
    Bulletin de la Societe belge d'ophtalmologie, 1972, Volume: 160, Issue:1

    Topics: Analgesics; Anti-Inflammatory Agents; Antimalarials; Aspirin; Color Vision Defects; Corneal Opacity;

1972
Pharmacology of a new non-steroidal anti-inflammatory agent 7-chloro-3,3a-dihydro-2-methyl-2H,9H-isoxazolo-(3,2-b)(1,3)-benzoxazin-9-one (W-2395).
    European journal of pharmacology, 1974, Volume: 26, Issue:1

    Topics: Adjuvants, Immunologic; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoxazi

1974
Comparative anti-phlogistic activity of delta 9-tetrahydrocannabinol, hydrocortisone and aspirin in various rat paw edema models.
    Life sciences, 1974, Jul-15, Volume: 15, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dronabinol; Edema; Hydrocortisone; Male; Rats; Rats, Inb

1974
[Release of edemas in the rat paw due to sodium nucleinate and their modification by antiphlorgistic agents].
    Die Pharmazie, 1972, Volume: 27, Issue:12

    Topics: Animals; Aspirin; Disease Models, Animal; Edema; Escherichia coli; Forelimb; Prednisolone; Pyrogens;

1972
Clinical and therapeutical problems concerning postthrombotic indurations.
    Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 52

    Topics: Ascorbic Acid; Aspirin; Atrophy; Auscultation; Cellulitis; Drug Combinations; Edema; Humans; Leg Ulc

1972
Some quantitative temporal characteristics of carrageenin-induced pleurisy in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 143, Issue:3

    Topics: Animals; Aspirin; Carrageenan; Cyproheptadine; Edema; Exudates and Transudates; Injections; Leukocyt

1973
Effect of steroidal and nonsteroidal anti-inflammatory compounds in a milkweed-sap-induced rat pedal edema.
    Steroids and lipids research, 1973, Volume: 4, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Biological Assay; Chlorpromazine; Cyproheptadine; Dexame

1973
Anti-edema and analgesic properties of delta9-tetrahydrocannabinol (THC).
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:3

    Topics: Abdomen; Acetates; Adjuvants, Immunologic; Adrenal Glands; Adrenalectomy; Analgesics; Animals; Anti-

1973
Influence of prostaglandins (Pg) E2 and F2 on the inflammatory process.
    Prostaglandins, 1973, Volume: 3, Issue:6

    Topics: Animals; Arthritis; Aspirin; Carrageenan; Croton Oil; Edema; Foot; Granuloma; Hindlimb; Hydrocortiso

1973
Antipyretic, analgesic and anti-inflammatory effects of delta 9-tetrahydrocannabinol in the rat.
    European journal of pharmacology, 1973, Volume: 24, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Body Temperature; Cannabis; Carrageenan; Dos

1973
Pharmacological properties of imidazole. I. Analgesic and anti-inflammatory actions.
    Pharmacology, 1973, Volume: 10, Issue:3

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Arthritis; Aspirin; Brad

1973
[Pharmacological studies on N-benzoyl-N'-phenyl-2,6-diaminobenzoic acid (F-1). 1. Anti-inflammatory action].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:5

    Topics: Adrenal Glands; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis; Ascorbic Acid; Aspirin; B

1973
Pharmacology of a new analgesic, antipyretic, and anti-inflammatory agent, 4-allyloxy-3-chlorophenylacetic acid.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:5

    Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carrageenan; Codeine

1970
[Cytostatic antiphlogistics. II. Antimicrobial activity range and comparison in the Oedipus test].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agen

1970
Antiarthritic and antiinflammatory effects of certain prostaglandins.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:1

    Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Blood Sedimentation; Body Wei

1972
Anti-inflammatory and other properties of 2,3-dihydrol-1-H-pyridino-(2,3- b) (1,4)-thiazine-2-one; ABBott-29590.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 196, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Dogs; Edema; Fever; Gastric Mucos

1972
Objective method for evaluation of analgesic-anti-inflammatory activity.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Edema; Evaluation Studies as Topic; Female;

1972
Some anti-inflammatory properties of ascorbic acid.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Ascorbic Acid; Aspirin; Carrageenan; Disease Models, A

1972
[Anti-inflammatory effect of bimetopyrol. I. Suppressive effect on acute inflammation].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1972, Volume: 92, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyproheptadine; Edema; Erythema; Fever; Flufenamic Acid;

1972
Release of lysosomal enzymes in experimental inflammations: effects of anti-inflammatory drugs.
    European journal of pharmacology, 1972, Volume: 19, Issue:2

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; C

1972
The influence of anti-inflammatory and immunosuppressant drugs on Nystatin induced oedema.
    Pharmacology, 1971, Volume: 5, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Arthritis; Aspirin; Azathioprine; Ch

1971
Anti-inflammatory and analgetic properties of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen).
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:1

    Topics: Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Fe

1971
Antiinflammatory 3,4-dihydro-2-alkyl-3-oxo-2H-1,2-benzothiazine-4-carboxamide 1,1-dioxides.
    Journal of medicinal chemistry, 1971, Volume: 14, Issue:10

    Topics: Administration, Oral; Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Drug Interactions;

1971
On the paw edema induced by subcutaneous injection of minute glass particles in the rat.
    Agents and actions, 1971, Volume: 2, Issue:1

    Topics: Administration, Oral; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Edema; Extremities; G

1971
3-Benzoyldifluoromethanesulfonanilide, sodium salt (diflumidone sodium, MBR 4164-8): a new anti-inflammatory agent.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 189, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoates; Car

1971
Effects of topical hydrocortisone and acetylsalicylic acid on the primary lesion of adjuvant-induced arthritis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 137, Issue:4

    Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin

1971
A histopathological and pharmacological analysis of the mode of action of nonsteroidal anti-inflammatory drugs.
    The Journal of pathology, 1971, Volume: 105, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Bone Marrow; Carrageenan; Edema; Indomethacin; Leukocyte

1971
Applications of the mouse foot edema test in evaluation of anti-cholera drugs.
    Research communications in chemical pathology and pharmacology, 1971, Volume: 2, Issue:2

    Topics: Animals; Anti-Infective Agents; Aspirin; Chloramphenicol; Cholera; Cycloheximide; Dactinomycin; Diur

1971
Concerning the nature of intolerance to aspirin.
    The Journal of allergy, 1967, Volume: 40, Issue:5

    Topics: Aminopyrine; Antipyrine; Aspirin; Asthma; Chemoreceptor Cells; Drug Hypersensitivity; Edema; Histami

1967
Diaryloxazole and diarylthiazolealkanoic acids: two novel series of non-steroidal anti-inflammatory agents.
    Nature, 1968, Jul-13, Volume: 219, Issue:5150

    Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Aspirin; Biological Assay; Carrageenan; Edema; Gastric

1968
Investigation of the carrageenin-induced rat paw edema assay and correlation between anti-inflammatory activity and gastric hemorrhage production in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 185, Issue:2

    Topics: Adrenalectomy; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Croton Oil; Edem

1970
[Effects of aspirin and salicylates on the gastric mucosa].
    Giornale di clinica medica, 1970, Volume: 51, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Aspirin; Edema; Female; Gastric Mucosa; Gastritis; Gastroin

1970
Observations on the pharmacological properties of inflammatory exudate.
    European journal of pharmacology, 1969, Volume: 8, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Calcium; Carrageenan; Ede

1969
Effect of aspirin on strength-duration curve of the traumatized muscle in cats.
    The Journal of trauma, 1970, Volume: 10, Issue:1

    Topics: Animals; Aspirin; Cats; Edema; Muscle Contraction; Muscle Denervation; Muscles

1970
Interactions of anti-inflammatory drugs in carrageenan-induced foot edema of the rat.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 172, Issue:2

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Female; Foot Diseases; Hyd

1970
Pharmacological properties of some antirheumatic salicylates.
    Acta pharmacologica et toxicologica, 1970, Volume: 28, Issue:4

    Topics: Animals; Aspirin; Edema; Female; Gastric Mucosa; Guinea Pigs; Rats; Salicylates; Sulfates; Sulfur Is

1970
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. I. Anti-inflammatory, analgesic and anti-pyretic activity.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Capill

1970
Pharmacological investigations of 2-amino-3-ethoxy-carbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Body Temperature; Bradykinin; C

1970
Factors influencing the inhibitory action of anti-inflammatory drugs on carrageenin induced oedema.
    British journal of pharmacology, 1971, Volume: 41, Issue:1

    Topics: Administration, Oral; Animals; Aspirin; Carrageenan; Edema; Female; Hindlimb; Humidity; Indomethacin

1971
Anti-inflammatory and liver sulfhydryl content-altering effects of certain nonsteroids in the rat.
    Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:3

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Chlorpromazine; Cyproheptadine;

1971
[Ethoxose edema of the rat paw and its influencing by acetylsalicylic acid, damascenine, phenylbutazone and salicylamide].
    Acta biologica et medica Germanica, 1967, Volume: 18, Issue:2

    Topics: Analgesics; Animals; Aspirin; Edema; Injections, Intraperitoneal; Methylcellulose; Phenylbutazone; R

1967
Quantitative studies concerning kaolin edema formation in rats.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 161, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Biological Assay; Edema; Hydrocortisone; Kaolin; Male; P

1968
Anti-inflammatory and related properties of 4-(p-biphenylyl)-3-hydroxybutyric acid.
    British journal of pharmacology and chemotherapy, 1968, Volume: 33, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Biphenyl Compounds; Blood Pressure; Bronchial

1968
Antiinflammatory 2-aryl-1,3-indandiones.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Blood Coagulation; Carrageenan; Chemical

1968
Primary erythermalgia. Report of a patient treated with methysergide maleate.
    JAMA, 1968, Mar-18, Volume: 203, Issue:12

    Topics: Aspirin; Caffeine; Codeine; Edema; Erythromelalgia; Female; Humans; Maleates; Methysergide; Middle A

1968
Action of antiinflammatory drugs on the lysozyme activity and "turbidity" of serum from rats with adjuvant arthritis or endocrine deficiency.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 165, Issue:2

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Blood Proteins; Edema; Freund'

1969
Biphasic development of carrageenin edema in rats.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 166, Issue:1

    Topics: Animals; Aspirin; Body Temperature; Carrageenan; Edema; Foot; Hydrocortisone; Indomethacin; Male; Ph

1969
Evans blue-carrageenan pleural effusion as a model for the assay of nonsteroidal antirheumatic drugs.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carrageenan; Chloroquine; Coloring Agents; Ed

1969
Radiometric measurement of paw temperature changes associated with local inflammation.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 154, Issue:1

    Topics: Animals; Aspirin; Body Temperature; Chlorpheniramine; Edema; Inflammation; Radiometry; Rats; Yeasts

1966