aspirin has been researched along with Ectopic Ossification in 14 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of this study is to examine if aspirin (ASA), when used as venous thromboembolism (VTE) prophylaxis, influenced the rate of HO formation following TJA." | 8.02 | Low-Dose Aspirin Administered for Venous Thromboembolism Prophylaxis Reduces the Incidence of Heterotopic Ossification in Total Joint Arthroplasty. ( Chisari, E; Clarkson, S; Parvizi, J; Sherman, MB; Van Nest, DS, 2021) |
| " The purpose of this study is to examine if aspirin (ASA), when used as venous thromboembolism (VTE) prophylaxis, influenced the rate of HO formation following TJA." | 4.02 | Low-Dose Aspirin Administered for Venous Thromboembolism Prophylaxis Reduces the Incidence of Heterotopic Ossification in Total Joint Arthroplasty. ( Chisari, E; Clarkson, S; Parvizi, J; Sherman, MB; Van Nest, DS, 2021) |
| " Of the fifty-eight patients who had received aspirin throughout their course in the hospital, two (3 per cent) had severe ectopic ossification (grade III or IV8)." | 3.68 | Effect of aspirin on heterotopic ossification after total hip arthroplasty in men who have osteoarthrosis. ( Pagnani, MJ; Pellicci, PM; Salvati, EA, 1991) |
| "The role of aspirin in the prevention of heterotopic ossification (HO) following total hip arthroplasty (THA) has been debated." | 1.36 | Heterotopic ossification is less after THA in patients who receive aspirin compared to coumadin. ( Cohn, RM; Cornell, CN; Della Valle, AG, 2010) |
| "Aspirin treatment was instituted the night before surgery and continued for two weeks, except in 13 patients (7%) who had to stop treatment because of gastrointestinal symptoms." | 1.28 | The use of aspirin to prevent heterotopic ossification after total hip arthroplasty. A preliminary report. ( Cantor, R; Freiberg, AA; Freiberg, RA, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, J | 1 |
| Gao, J | 1 |
| Chen, J | 1 |
| Hou, J | 1 |
| Liu, M | 1 |
| Dang, Y | 1 |
| Lin, H | 1 |
| Van Nest, DS | 1 |
| Clarkson, S | 1 |
| Chisari, E | 1 |
| Sherman, MB | 1 |
| Parvizi, J | 1 |
| White, PB | 1 |
| Ramkumar, PN | 1 |
| Meftah, M | 1 |
| Ghazi, N | 1 |
| Ranawat, AS | 1 |
| Ranawat, CS | 1 |
| Bek, D | 1 |
| Beksaç, B | 1 |
| Della Valle, AG | 2 |
| Sculco, TP | 1 |
| Salvati, EA | 2 |
| Cohn, RM | 1 |
| Cornell, CN | 1 |
| Nunley, RM | 1 |
| Zhu, J | 1 |
| Clohisy, JC | 1 |
| Barrack, RL | 1 |
| Eyb, R | 1 |
| Knahr, K | 1 |
| Knelles, D | 2 |
| Barthel, T | 2 |
| Karrer, A | 1 |
| Kraus, U | 1 |
| Eulert, J | 2 |
| Kölbl, O | 1 |
| Neal, BC | 1 |
| Rodgers, A | 1 |
| Gray, H | 1 |
| Clark, T | 1 |
| Beaumont, DD | 1 |
| House, T | 1 |
| Douglas, JE | 1 |
| Reid, IR | 1 |
| MacMahon, SW | 1 |
| Kjaersgaard-Andersen, P | 1 |
| Ritter, MA | 1 |
| Freiberg, AA | 1 |
| Cantor, R | 1 |
| Freiberg, RA | 1 |
| Pagnani, MJ | 1 |
| Pellicci, PM | 1 |
| Lazansky, MG | 1 |
1 review available for aspirin and Ectopic Ossification
| Article | Year |
|---|---|
Incidence of Heterotopic Ossification Following a Multimodal Pain Protocol in Total Hip Arthroplasty With the Posterior Approach.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, | 2018 |
4 trials available for aspirin and Ectopic Ossification
| Article | Year |
|---|---|
The effect of prophylaxis for thrombosis on heterotopic ossification following total hip joint replacement.
Topics: Aspirin; Heparin; Hip Prosthesis; Humans; Ossification, Heterotopic; Oxyphenbutazone; Thrombosis | 1983 |
Prevention of heterotopic ossification after total hip replacement. A prospective, randomised study using acetylsalicylic acid, indomethacin and fractional or single-dose irradiation.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Hip Prosthesis; Humans; Indomethacin | 1997 |
[Heterotopic ossifications].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthrography; Arthroplasty, Replacement, Hip; Aspirin | 1997 |
No effect of low-dose aspirin for the prevention of heterotopic bone formation after total hip replacement: a randomized trial of 2,649 patients.
Topics: Activities of Daily Living; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement | 2000 |
9 other studies available for aspirin and Ectopic Ossification
| Article | Year |
|---|---|
Berberine and aspirin prevent traumatic heterotopic ossification by inhibition of BMP signalling pathway and osteogenic differentiation.
Topics: AMP-Activated Protein Kinases; Animals; Aspirin; Berberine; Cell Differentiation; Mice; Ossification | 2023 |
Low-Dose Aspirin Administered for Venous Thromboembolism Prophylaxis Reduces the Incidence of Heterotopic Ossification in Total Joint Arthroplasty.
Topics: Arthroplasty, Replacement, Hip; Aspirin; Humans; Incidence; Ossification, Heterotopic; Risk Factors; | 2021 |
Aspirin decreases the prevalence and severity of heterotopic ossification after 1-stage bilateral total hip arthroplasty for osteoarthrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Arthroplasty, Replacement, Hip; Aspir | 2009 |
Heterotopic ossification is less after THA in patients who receive aspirin compared to coumadin.
Topics: Aged; Arthroplasty, Replacement, Hip; Aspirin; Chi-Square Distribution; Elective Surgical Procedures | 2010 |
Aspirin decreases heterotopic ossification after hip resurfacing.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Aspirin; Female; Follow-Up | 2011 |
Short-term treatment with nonsteroidal antiinflammatory medications to prevent heterotopic bone formation after total hip arthroplasty. A preliminary report.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Hip Prosthesis; Humans; Indomethacin; Male; Middle Aged; Os | 1992 |
The use of aspirin to prevent heterotopic ossification after total hip arthroplasty. A preliminary report.
Topics: Aspirin; Female; Hip Prosthesis; Humans; Male; Ossification, Heterotopic; Retrospective Studies | 1991 |
Effect of aspirin on heterotopic ossification after total hip arthroplasty in men who have osteoarthrosis.
Topics: Aged; Aged, 80 and over; Aspirin; Hip Prosthesis; Humans; Length of Stay; Male; Middle Aged; Ossific | 1991 |
Complications revisited. The debit side of total hip replacement.
Topics: Anti-Bacterial Agents; Arthritis, Rheumatoid; Arthroplasty; Aspirin; Bone Cements; Dextrans; Female; | 1973 |