aspirin has been researched along with EHS Tumor in 11 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The growth rate (studied by mean tumor dry weight) and vascularization (studied by microangiography) of two transplantable rat tumors, a 20-methylcholanthrene-induced fibrosarcoma and a hepatoma, were significantly reduced by three prostaglandin synthesis inhibitors, indomethacin, diclofenac-sodium and aspirin, irrespective of whether the drugs were administered early or late during tumor growth." | 3.66 | Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat. ( Peterson, HI, 1983) |
| "The growth of a 3-methylcholanthrene-induced fibrosarcoma of C3H mice was inhibited by aspirin and indomethacin." | 3.66 | Mechanism of inhibition of tumour growth by aspirin and indomethacin. ( Astoin, M; Castes, M; Lynch, NR; Salomon, JC, 1978) |
| "Aspirin is a salicylate drug that is widely used, and recently it has been shown to influence the development of various types of cancers." | 1.39 | Impact of acetylsalicylic acid on tumor angiogenesis and lymphangiogenesis through inhibition of VEGF signaling in a murine sarcoma model. ( Jia, Q; Wang, Z; Wu, L; Zhang, W; Zhang, X; Zhang, Y, 2013) |
| "An increase of extrapulmonary metastases was used as a measure of increased redistribution of tumor cells from lungs to other organs." | 1.26 | Influence of aspirin and/or anabolic steroid (nandrolone decanoate) on experimental metastasis formation. ( Boeryd, B; Kanclerz, A; Zbytniewski, Z, 1981) |
| "aspirin were given daily." | 1.26 | Prostaglandin-mediated hypercalcemia in transitional cell carcinoma of the bladder. ( Gavrell, GJ; Kaplan, RA; Le Blanc, GA; McKay, HA; Meehan, WL, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, X | 1 |
| Wang, Z | 2 |
| Zhang, Y | 1 |
| Jia, Q | 1 |
| Wu, L | 1 |
| Zhang, W | 1 |
| Peterson, HI | 1 |
| Grignani, G | 2 |
| Almasio, P | 1 |
| Pacchiarini, L | 2 |
| Ricetti, MM | 1 |
| Serra, L | 2 |
| Gamba, G | 2 |
| Gorini, M | 1 |
| Zbytniewski, Z | 1 |
| Kanclerz, A | 1 |
| Boeryd, B | 1 |
| Carmel, RJ | 1 |
| Brown, JM | 1 |
| Seifter, E | 1 |
| Rettura, G | 1 |
| Levenson, SM | 1 |
| Appleman, M | 1 |
| Seifter, J | 1 |
| Lynch, NR | 1 |
| Castes, M | 1 |
| Astoin, M | 1 |
| Salomon, JC | 1 |
| McKay, HA | 1 |
| Gavrell, GJ | 1 |
| Meehan, WL | 1 |
| Kaplan, RA | 1 |
| Le Blanc, GA | 1 |
| Tashjian, AH | 1 |
| Voelkel, EF | 1 |
| Goldhaber, P | 1 |
| Levine, L | 1 |
| Hochschild, R | 1 |
11 other studies available for aspirin and EHS Tumor
| Article | Year |
|---|---|
Impact of acetylsalicylic acid on tumor angiogenesis and lymphangiogenesis through inhibition of VEGF signaling in a murine sarcoma model.
Topics: Animals; Aspirin; Fluorouracil; Lymphangiogenesis; Lymphatic Vessels; Male; Mice; Neovascularization | 2013 |
Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat.
Topics: Animals; Aspirin; Diclofenac; Fibrosarcoma; Indomethacin; Liver Neoplasms, Experimental; Neoplasm Tr | 1983 |
Interactions between neoplastic cells with different metastasizing capacity and platelet function.
Topics: Adenosine Diphosphate; Adult; Animals; Aspirin; Blood Platelets; Cell Line; Cells, Cultured; Culture | 1983 |
[In vitro effect of culture fluids from neoplastic tissues on platelet aggregation. II. Experimental tumors].
Topics: Adenosine Diphosphate; Adult; Animals; Aspirin; Culture Media; Female; Humans; Male; Mice; Platelet | 1982 |
Influence of aspirin and/or anabolic steroid (nandrolone decanoate) on experimental metastasis formation.
Topics: Animals; Aspirin; Drug Interactions; Mice; Nandrolone; Neoplasm Metastasis; Platelet Aggregation; Sa | 1981 |
The effect of cyclophosphamide and other drugs on the incidence of pulmonary metastases in mice.
Topics: Age Factors; Animals; Antineoplastic Agents; Aspirin; Cyclophosphamide; Dactinomycin; Dose-Response | 1977 |
Aspirin inhibits a murine viral infection.
Topics: Adrenocorticotropic Hormone; Animals; Antiviral Agents; Aspirin; Male; Mice; Mice, Inbred CBA; Molon | 1975 |
Mechanism of inhibition of tumour growth by aspirin and indomethacin.
Topics: Animals; Antibodies, Neoplasm; Aspirin; Female; Fibrosarcoma; Hemolytic Plaque Technique; Immunosupp | 1978 |
Prostaglandin-mediated hypercalcemia in transitional cell carcinoma of the bladder.
Topics: Animals; Aspirin; Calcium; Carcinoma, Transitional Cell; Chemical Phenomena; Chemistry; Female; Fibr | 1978 |
Prostaglandins, calcium metabolism and cancer.
Topics: Animals; Aspirin; Bone and Bones; Bone Resorption; Calcium; Calcium Radioisotopes; Cells, Cultured; | 1974 |
Effects of various additives on in vitro survival time of mouse macrophages.
Topics: Animals; Antioxidants; Aspirin; Cell Membrane; Cell Survival; Cells, Cultured; Cresols; Culture Medi | 1973 |