aspirin has been researched along with Dysplastic Nevus Syndrome, Hereditary in 3 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of aspirin on melanoma are unclear, with studies reporting conflicting results." | 9.51 | Effect of Aspirin on Melanoma Incidence in Older Persons: Extended Follow-up of a Large Randomized Double-blind Placebo-controlled Trial. ( Adler, NR; Chan, AT; Gibbs, P; Haydon, A; Mar, VJ; McLean, C; Orchard, SG; Rodriguez, LM; Wolfe, R; Woods, RL; Yan, MK, 2022) |
| "The association between hypertension and melanoma is unclear, and previous analyses of data from the ASPirin in Reducing Events in the Elderly (ASPREE) study demonstrated a reduced number of invasive melanoma events amongst aspirin-exposed hypertensive individuals." | 8.12 | Association between hypertension and cutaneous melanoma, and the effect of aspirin: extended follow-up of a large randomised controlled trial. ( Adler, NR; Chan, AT; Gibbs, P; Haydon, A; Mar, VJ; McLean, C; Orchard, SG; Rodríguez, LM; Wolfe, R; Woods, RL; Yan, MK, 2022) |
| "The effects of aspirin on melanoma are unclear, with studies reporting conflicting results." | 5.51 | Effect of Aspirin on Melanoma Incidence in Older Persons: Extended Follow-up of a Large Randomized Double-blind Placebo-controlled Trial. ( Adler, NR; Chan, AT; Gibbs, P; Haydon, A; Mar, VJ; McLean, C; Orchard, SG; Rodriguez, LM; Wolfe, R; Woods, RL; Yan, MK, 2022) |
| "The association between hypertension and melanoma is unclear, and previous analyses of data from the ASPirin in Reducing Events in the Elderly (ASPREE) study demonstrated a reduced number of invasive melanoma events amongst aspirin-exposed hypertensive individuals." | 4.12 | Association between hypertension and cutaneous melanoma, and the effect of aspirin: extended follow-up of a large randomised controlled trial. ( Adler, NR; Chan, AT; Gibbs, P; Haydon, A; Mar, VJ; McLean, C; Orchard, SG; Rodríguez, LM; Wolfe, R; Woods, RL; Yan, MK, 2022) |
| " In a cross-sectional study of 787 patients with newly diagnosed clinical stage IB or II melanoma, we estimated odds ratios for the association of proinflammatory factors (high body mass index, diabetes, cardiovascular disease, hypertension, and smoking) or the use of anti-inflammatory medications (statins, aspirin, corticosteroids, and nonsteroidal anti-inflammatory drugs), with ulcerated primary melanoma using regression models and subgroup analyses to control for melanoma thickness and mitotic rate." | 3.85 | Associations of Statins and Diabetes with Diagnosis of Ulcerated Cutaneous Melanoma. ( Green, AC; Hughes, MCB; Khosrotehrani, K; Malt, M; Smith, D; Smithers, BM; van der Pols, JC; von Schuckmann, LA, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Yan, MK | 2 |
| Orchard, SG | 2 |
| Adler, NR | 2 |
| Wolfe, R | 2 |
| McLean, C | 2 |
| Rodriguez, LM | 2 |
| Woods, RL | 2 |
| Gibbs, P | 2 |
| Chan, AT | 2 |
| Haydon, A | 2 |
| Mar, VJ | 2 |
| von Schuckmann, LA | 1 |
| Smith, D | 1 |
| Hughes, MCB | 1 |
| Malt, M | 1 |
| van der Pols, JC | 1 |
| Khosrotehrani, K | 1 |
| Smithers, BM | 1 |
| Green, AC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Aspirin in Reducing Events in the Elderly[NCT01038583] | 19,114 participants (Actual) | Observational | 2010-01-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for aspirin and Dysplastic Nevus Syndrome, Hereditary
| Article | Year |
|---|---|
Effect of Aspirin on Melanoma Incidence in Older Persons: Extended Follow-up of a Large Randomized Double-blind Placebo-controlled Trial.
Topics: Aged; Aspirin; Double-Blind Method; Female; Follow-Up Studies; Humans; Incidence; Male; Melanoma; Me | 2022 |
2 other studies available for aspirin and Dysplastic Nevus Syndrome, Hereditary
| Article | Year |
|---|---|
Association between hypertension and cutaneous melanoma, and the effect of aspirin: extended follow-up of a large randomised controlled trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Follow-Up Studies; Humans; Melanoma; Melanom | 2022 |
Associations of Statins and Diabetes with Diagnosis of Ulcerated Cutaneous Melanoma.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Sectio | 2017 |