Page last updated: 2024-10-23

aspirin and Dysmenorrhea

aspirin has been researched along with Dysmenorrhea in 46 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Dysmenorrhea: Painful menstruation.

Research Excerpts

ExcerptRelevanceReference
"Reports on the efficacy of flurbiprofen for dysmenorrhea conflict."9.05Flurbiprofen in dysmenorrhea. ( DeLia, JE; Emery, MG; Scott, JR; Taylor, RH, 1982)
"We compared fenoprofen calcium, 200 mg; fenoprofen calcium, 400 mg; aspirin, 650 mg; and a placebo in 85 women for the relief of primary dysmenorrhea in a double-blind, clinical trial."9.05Efficacy of fenoprofen in the treatment of primary dysmenorrhea. ( Burt, RA; Caldwell, BV; Kaul, AF; Naftolin, F; Osathanondh, R; Scavone, JM; Sokoloff, BJ; White, RM, 1985)
"In a double-blind, crossover study of 32 women with primary dysmenorrhea, the analgesic efficacy of naproxen sodium was compared to that of aspirin and placebo."7.66Naproxen sodium, aspirin, and placebo in primary dysmenorrhea. Reduction of pain and blood levels of prostaglandin F2-alpha metabolite. ( Dubin, NH; Ghodgaonkar, RB; Henzl, MR; Hoffman, S; Jones, GS; Rosenwaks, Z, 1981)
"Flurbiprofen was also rated superior to aspirin and placebo in the degree of pain relief."6.66Flurbiprofen for the treatment of primary dysmenorrhea. ( Shapiro, SS, 1986)
" The intended dosage was 2 tablets every 4 hours as necessary for relief of menstrual pain."6.64Ibuprofen therapy for dysmenorrhea. ( Bolognese, RJ; Corson, SL, 1978)
"Piroxicam, a NSAID with a proved analgesic and antiphlogistic efficacy, largely used in rheumatic-orthopedic pathologies, has an antalgic action also in extra-rheumatic pathologies, such as postoperative and dental pain and primary dysmenorrhea."6.16[Piroxicam in analgesia]. ( della Pepa, C; Eandi, M; Rubinetto, MP, 1991)
" As for efficacy outcomes, all the included analgesics except aspirin were more effective than placebo in treating dysmenorrhea [naproxen (OR 3."5.05Efficacy and safety of over-the-counter analgesics for primary dysmenorrhea: A network meta-analysis. ( Chen, Y; Hao, C; Nie, W; Wang, L; Xu, P; Yin, Y, 2020)
"1 In a double-blind crossover study, flurbiprofen produced marked relief of pain which was significantly more than with aspirin and placebo in patients suffering from primary dysmenorrhoea."5.05Flurbiprofen in the treatment of primary dysmenorrhoea. ( Gupta, KC; Krishna, UR; Kulkarni, VN; Mandlekar, A; Naik, S; Sheth, UK, 1980)
"Reports on the efficacy of flurbiprofen for dysmenorrhea conflict."5.05Flurbiprofen in dysmenorrhea. ( DeLia, JE; Emery, MG; Scott, JR; Taylor, RH, 1982)
"We compared fenoprofen calcium, 200 mg; fenoprofen calcium, 400 mg; aspirin, 650 mg; and a placebo in 85 women for the relief of primary dysmenorrhea in a double-blind, clinical trial."5.05Efficacy of fenoprofen in the treatment of primary dysmenorrhea. ( Burt, RA; Caldwell, BV; Kaul, AF; Naftolin, F; Osathanondh, R; Scavone, JM; Sokoloff, BJ; White, RM, 1985)
"Two commonly taken over-the-counter analgesics, aspirin and acetaminophen, were compared for: effect on total menstrual loss, effect on total days of menstruation, and effect in reduction of pain due to headaches and/or menstrual cramps."3.67Do aspirin and acetaminophen affect total menstrual loss? ( Agna, MA; Pendergrass, PB; Ream, LJ; Scott, JN, 1984)
"In a double-blind, crossover study of 32 women with primary dysmenorrhea, the analgesic efficacy of naproxen sodium was compared to that of aspirin and placebo."3.66Naproxen sodium, aspirin, and placebo in primary dysmenorrhea. Reduction of pain and blood levels of prostaglandin F2-alpha metabolite. ( Dubin, NH; Ghodgaonkar, RB; Henzl, MR; Hoffman, S; Jones, GS; Rosenwaks, Z, 1981)
"Flurbiprofen was also rated superior to aspirin and placebo in the degree of pain relief."2.66Flurbiprofen for the treatment of primary dysmenorrhea. ( Shapiro, SS, 1986)
"Indomethacin treatment raised the incidence of psychic complaints over those with ASA or placebo (P."2.65Prostaglandin biosynthesis inhibitors and endometriosis. ( Kauppila, A; Puolakka, J; Ylikorkala, O, 1979)
"Indomethacin proved to be a valuable agent, and significantly better than aspirin in the treatment of dysmenorrhoea."2.64Indomethacin in the treatment of primary dysmenorrhoea. ( Kajanoja, P, 1978)
" The intended dosage was 2 tablets every 4 hours as necessary for relief of menstrual pain."2.64Ibuprofen therapy for dysmenorrhea. ( Bolognese, RJ; Corson, SL, 1978)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199035 (76.09)18.7374
1990's4 (8.70)18.2507
2000's4 (8.70)29.6817
2010's2 (4.35)24.3611
2020's1 (2.17)2.80

Authors

AuthorsStudies
Nie, W1
Xu, P1
Hao, C1
Chen, Y1
Yin, Y1
Wang, L1
Espín López, L1
Carrillo Verdejo, E1
González Javier, F1
Ordoñana Martín, JR1
Gómez-Amor, J1
Latthe, PM1
Champaneria, R1
Khan, KS1
CHAMBLIN, WD1
CORBIT, JD1
SNIVELY, SA1
VITSE, M1
WARNER, RS1
SCALZERLE, V1
Proctor, M3
Farquhar, C3
Proctor, ML1
Farquhar, CM1
Kraus, I1
Horský, A1
Presl, J1
Hrádek, D1
Petr, J1
Kümmel, M1
Uzel, R1
Chan, WY1
Pendergrass, PB1
Ream, LJ1
Scott, JN1
Agna, MA1
Mishell, DR1
Fisher, HW1
Haynes, PJ1
Jones, GS2
Smith, RP1
Alvin, PE1
Litt, IF2
Krishna, UR1
Naik, S1
Mandlekar, A1
Gupta, KC1
Kulkarni, VN1
Sheth, UK1
Pogmore, JR1
Filshie, GM1
DeLia, JE1
Emery, MG1
Taylor, RH1
Scott, JR1
Klein, JR1
Rosenberg, A1
Udall, L1
Rosenwaks, Z1
Henzl, MR1
Dubin, NH1
Ghodgaonkar, RB1
Hoffman, S1
Lee, SG1
Matsuyoshi, N1
Ohta, K1
Horiguchi, Y1
Imamura, S1
Zhang, WY1
Li Wan Po, A1
Pedrón-Nuevo, N1
González-Unzaga, LN1
De Celis-Carrillo, R1
Reynoso-Isla, M1
de la Torre-Romeral, L1
Kajanoja, P1
Corson, SL1
Bolognese, RJ1
Janbu, T2
Løkken, P3
Nesheim, BI2
Gould, CH1
Nesheim, B1
Kauppila, A1
Puolakka, J1
Ylikorkala, O1
Shangold, MM1
Aksel, S1
Schomberg, DW1
Hammond, CB1
Eandi, M1
della Pepa, C1
Rubinetto, MP1
Zahradnik, HP1
Breckwoldt, M1
Gookin, KS1
Griffis, KR1
McGehee, RP1
Wiser, WL1
Morrison, JC1
Shapiro, SS1
Lundström, V1
Osathanondh, R1
Caldwell, BV1
Kaul, AF1
Sokoloff, BJ1
White, RM1
Scavone, JM1
Burt, RA1
Naftolin, F1
Nathan, LA1
Kemp, JH1
Götz, HG1
Ogden, JA1
Wade, ME1
Anderson, G1
Davis, CD1
Sproule, BC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Premedication Hyoscine-N-butylbromide Before Hysterosalpingography for Diagnosis of Proximal Tubal Obstruction in Infertile Women : A Randomized Double-Blind Controlled Trial[NCT02618785]146 participants (Actual)Interventional2016-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for aspirin and Dysmenorrhea

ArticleYear
Efficacy and safety of over-the-counter analgesics for primary dysmenorrhea: A network meta-analysis.
    Medicine, 2020, Volume: 99, Issue:19

    Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Dysmeno

2020
Dysmenorrhoea.
    BMJ clinical evidence, 2011, Feb-21, Volume: 2011

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Denervation; Dysme

2011
Dysmenorrhoea.
    Clinical evidence, 2003, Issue:9

    Topics: Acetaminophen; Acupuncture Therapy; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Contraceptives

2003
Dysmenorrhoea.
    Clinical evidence, 2003, Issue:10

    Topics: Acetaminophen; Acupuncture Therapy; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Contraceptives

2003
Dysmenorrhoea.
    Clinical evidence, 2004, Issue:12

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drugs, Chinese Herbal; Dysmenorrhea

2004
Dysmenorrhoea.
    Clinical evidence, 2006, Issue:15

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drugs, Chinese Herbal; Dysmenorrhea

2006
Prostaglandins and nonsteroidal antiinflammatory drugs in dysmenorrhea.
    Annual review of pharmacology and toxicology, 1983, Volume: 23

    Topics: Anti-Inflammatory Agents; Aspirin; Contraceptives, Oral; Dysmenorrhea; Female; Humans; Ibuprofen; In

1983
Current status of the etiology and management of dysmenorrhea in adolescence.
    Pediatrics, 1982, Volume: 70, Issue:4

    Topics: Adolescent; Aspirin; Contraceptives, Oral; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Humans;

1982
Efficacy of minor analgesics in primary dysmenorrhoea: a systematic review.
    British journal of obstetrics and gynaecology, 1998, Volume: 105, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, No

1998
[Piroxicam in analgesia].
    La Clinica terapeutica, 1991, Jan-31, Volume: 136, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Tolerance; Dysmenorrhea; Female; Humans; Pain

1991
[Anti-dysmenorrhea drugs. 17].
    Pharmazeutische Praxis, 1967, Volume: 9

    Topics: Aminopyrine; Amphetamine; Analgesics; Aspirin; Atropa belladonna; Codeine; Dysmenorrhea; Ergot Alkal

1967

Trials

15 trials available for aspirin and Dysmenorrhea

ArticleYear
Flurbiprofen in the treatment of primary dysmenorrhoea.
    British journal of clinical pharmacology, 1980, Volume: 9, Issue:6

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Flu

1980
Flurbiprofen in the management of dysmenorrhoea.
    British journal of obstetrics and gynaecology, 1980, Volume: 87, Issue:4

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Flu

1980
Flurbiprofen in dysmenorrhea.
    Clinical pharmacology and therapeutics, 1982, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aspirin; Drug Evaluation; Dysmenorrhea; Female; Flurbiprofen; Humans; Propionates

1982
The effect of aspirin on dysmenorrhea in adolescents.
    The Journal of pediatrics, 1981, Volume: 98, Issue:6

    Topics: Adolescent; Aspirin; Dysmenorrhea; Female; Humans; Prostaglandin Antagonists

1981
Indomethacin in the treatment of primary dysmenorrhoea.
    Archiv fur Gynakologie, 1978, Feb-22, Volume: 225, Issue:1

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Hum

1978
Ibuprofen therapy for dysmenorrhea.
    The Journal of reproductive medicine, 1978, Volume: 20, Issue:5

    Topics: Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Dysmenorrhea; Female

1978
Effect of acetylsalicylic acid, paracetamol, and placebo on pain and blood loss in dysmenorrhoeic women.
    European journal of clinical pharmacology, 1978, Dec-18, Volume: 14, Issue:6

    Topics: Acetaminophen; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female;

1978
Effect of acetylsalicylic acid, paracetamol and placebo on pain and blood loss in dysmenorrheic women.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1979, Volume: 87

    Topics: Acetaminophen; Adult; Aspirin; Blood Specimen Collection; Blood Volume; Clinical Trials as Topic; Do

1979
Dydrogesterone in teenage dysmenorrhoea. A multicentre trial in general practice.
    The Practitioner, 1979, Volume: 222, Issue:1331

    Topics: Adolescent; Aspirin; Clinical Trials as Topic; Double-Blind Method; Dydrogesterone; Dysmenorrhea; Fa

1979
Prostaglandin biosynthesis inhibitors and endometriosis.
    Prostaglandins, 1979, Volume: 18, Issue:4

    Topics: Aspirin; Double-Blind Method; Dysmenorrhea; Endometriosis; Female; Humans; Indomethacin; ortho-Amino

1979
[Piroxicam in analgesia].
    La Clinica terapeutica, 1991, Jan-31, Volume: 136, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Tolerance; Dysmenorrhea; Female; Humans; Pain

1991
Flurbiprofen for the treatment of primary dysmenorrhea.
    The American journal of medicine, 1986, Mar-24, Volume: 80, Issue:3A

    Topics: Adolescent; Adult; Aspirin; Dinoprost; Dysmenorrhea; Female; Flurbiprofen; Humans; Middle Aged; Pain

1986
Efficacy of fenoprofen in the treatment of primary dysmenorrhea.
    The Journal of reproductive medicine, 1985, Volume: 30, Issue:12

    Topics: Adolescent; Adult; Analgesics; Aspirin; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea;

1985
"Buscopan" in spasmodic dysmenorrhoea.
    Current medical research and opinion, 1972, Volume: 1, Issue:1

    Topics: Administration, Oral; Aspirin; Bromine; Clinical Trials as Topic; Dysmenorrhea; Female; Humans; Plac

1972
Treatment of dysmenorrhea. A comparative double blind study.
    American journal of obstetrics and gynecology, 1970, Mar-15, Volume: 106, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Amphetamine; Analgesics; Aspirin; Barbiturates; Clinical Trials as

1970

Other Studies

21 other studies available for aspirin and Dysmenorrhea

ArticleYear
Incidence of anovulatory menstrual cycles among dysmenorrheic and non-non-dysmenorrheic [corrected] women: effects on symptomatology and mood.
    Psicothema, 2010, Volume: 22, Issue:4

    Topics: Adolescent; Affect; Amenorrhea; Anovulation; Aspirin; Body Temperature; Comorbidity; Dizziness; Dysm

2010
Chlorpromazine and chlorpromazine combinations in the treatment of dysmenorrhea.
    American journal of obstetrics and gynecology, 1957, Volume: 74, Issue:2

    Topics: Amphetamine; Amphetamines; Aspirin; Chlorpromazine; Codeine; Dysmenorrhea; Female; Humans; Phenaceti

1957
EVALUATION OF DRUG THERAPY IN DYSMENORRHEA OF COLLEGE WOMEN.
    Western medicine; the medical journal of the west, 1963, Volume: 4

    Topics: Alkaloids; Amphetamine; Amphetamines; Aspirin; Atropa belladonna; Barbiturates; Dysmenorrhea; Female

1963
[CLINICAL EXPERIMENTATION WITH TH-2152 IN GYNECOLOGY AND OBSTETRICS].
    Gazette medicale de France, 1964, Jun-10, Volume: 71

    Topics: Analgesia; Aspirin; Bicarbonates; Biomedical Research; Dysmenorrhea; Female; Gynecology; Headache; H

1964
THE EFFECTS OF THERAPY WITH A NONDEPRESSANT ANALGESIC COMBINATION.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Arthritis; Aspirin; Biomedical Research; Caffein

1964
[RESULTS OF USE OF PSYCHOPHARMACOLOGIC DRUGS IN THE TREATMENT OF DYSMENORRHEA].
    Minerva ginecologica, 1964, Sep-15, Volume: 16

    Topics: Aspirin; Biomedical Research; Drug Therapy; Dysmenorrhea; Female; Humans; Iproniazid; Psychopharmaco

1964
[Combined treatment of idiopathic dysmenorrhoea by acetylsalicylic acid and guaiphenezine (author's transl)].
    Ceskoslovenska gynekologie, 1981, Volume: 46, Issue:8

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Aspirin; Drug Combinations; Dysmenorrhea; Female; Guaifenesi

1981
Do aspirin and acetaminophen affect total menstrual loss?
    Gynecologic and obstetric investigation, 1984, Volume: 18, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Double-Blind Method; Dysmenorrhea; Female; He

1984
Menorrhagia. A symposium.
    The Journal of reproductive medicine, 1984, Volume: 29, Issue:10 Suppl

    Topics: Adolescent; Adult; Aminocaproates; Anti-Inflammatory Agents; Antifibrinolytic Agents; Aspirin; Blood

1984
Naproxen sodium, aspirin, and placebo in primary dysmenorrhea. Reduction of pain and blood levels of prostaglandin F2-alpha metabolite.
    American journal of obstetrics and gynecology, 1981, Jul-01, Volume: 140, Issue:5

    Topics: Activities of Daily Living; Adolescent; Adult; Aspirin; Dinoprost; Double-Blind Method; Drug Evaluat

1981
Drug eruption due to Bufferin showing erythema exsudativum multiforme with a photo-recall-like phenomenon.
    European journal of dermatology : EJD, 1998, Volume: 8, Issue:4

    Topics: Adult; Aspirin; Biopsy, Needle; Dermatitis, Photoallergic; Diagnosis, Differential; Drug Eruptions;

1998
[Incidence of dysmenorrhea and associated symptoms in women aged 12-24 years].
    Ginecologia y obstetricia de Mexico, 1998, Volume: 66

    Topics: Adolescent; Adult; Age Factors; Aspirin; Child; Dysmenorrhea; Female; Humans; Incidence; Mefenamic A

1998
[Antagonist of prostaglandin synthesis in the treatment of dysmenorrhea].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1979, Jun-10, Volume: 99, Issue:16

    Topics: Aspirin; Dysmenorrhea; Female; Humans; Indomethacin; Naproxen; Prostaglandin Antagonists

1979
Drugs for dysmenorrhea.
    The Medical letter on drugs and therapeutics, 1979, Oct-05, Volume: 21, Issue:20

    Topics: Acetaminophen; Aspirin; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Nalbu

1979
[Use of "mild" analgesics: More based on occasions and tradition then on rational bases?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1979, Aug-10, Volume: 99, Issue:22

    Topics: Analgesics; Aspirin; Drug Utilization; Dysmenorrhea; Female; Humans; Pain, Postoperative

1979
Plasma prostaglandin F 2-alpha levels in dysmenorrehic women.
    Fertility and sterility, 1976, Volume: 27, Issue:10

    Topics: Adult; Aspirin; Dysmenorrhea; Female; Humans; Luteinizing Hormone; Menstruation; Progestins; Prostag

1976
[Drug therapy of dysmenorrhea].
    Der Gynakologe, 1988, Volume: 21, Issue:1

    Topics: Adrenergic beta-Agonists; Adult; Aspirin; Calcium Channel Blockers; Contraceptives, Oral; Dysmenorrh

1988
The treatment of primary dysmenorrhea with flurbiprofen.
    Journal of the Mississippi State Medical Association, 1988, Volume: 29, Issue:4

    Topics: Adult; Aspirin; Dysmenorrhea; Female; Flurbiprofen; Humans; Propionates

1988
[Treatment of dysmenorrhea].
    Nordisk medicin, 1986, Volume: 101, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aspirin; Dysmenorrhea; Female; Humans; Indomethacin

1986
Dysmenorrhea and pre-menstrual tension in adolescents.
    IMJ. Illinois medical journal, 1967, Volume: 131, Issue:2

    Topics: Adolescent; Aspirin; Caffeine; Dysmenorrhea; Female; Humans; Orphenadrine; Phenacetin; Premenstrual

1967
"Fiorinal" in the treatment of tension headache and other painful states associated with nervous tension.
    The Medical journal of Australia, 1968, Feb-17, Volume: 1, Issue:7

    Topics: Adolescent; Adult; Analgesics; Aspirin; Barbiturates; Caffeine; Dysmenorrhea; Female; Headache; Huma

1968