Page last updated: 2024-10-23

aspirin and Dry Eye Syndromes

aspirin has been researched along with Dry Eye Syndromes in 4 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Dry Eye Syndromes: Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effects of acetylsalicylic acid (aspirin) on tear film parameters and dry eye disease."7.88The Effect of Low-Dose Aspirin on Dry Eye Parameters and Ocular Surface Disease Index Questionnaire. ( Ayhan, E; Ermiş, SS; Gürbüzer, T; Kurt, H; Şahin, G; Sarı, E; Tıskaoğlu, NS; Yazıcı, A, 2018)
"To evaluate the effects of acetylsalicylic acid (aspirin) on tear film parameters and dry eye disease."3.88The Effect of Low-Dose Aspirin on Dry Eye Parameters and Ocular Surface Disease Index Questionnaire. ( Ayhan, E; Ermiş, SS; Gürbüzer, T; Kurt, H; Şahin, G; Sarı, E; Tıskaoğlu, NS; Yazıcı, A, 2018)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yazıcı, A1
Sarı, E1
Ayhan, E1
Şahin, G1
Tıskaoğlu, NS1
Gürbüzer, T1
Kurt, H1
Ermiş, SS1
Tong, L1
Wong, TY1
Kroshinsky, D1
Stone, JH1
Bloch, DB1
Sepehr, A1
Schaumberg, DA1
Sullivan, DA1
Buring, JE1
Dana, MR1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Breathing Exercises and Meditation on Health-Related Quality of Life in Dry Eye Disease Patients: A Pilot Study[NCT03345381]70 participants (Anticipated)Interventional2019-07-01Not yet recruiting
Women's Health Study of Low-dose Aspirin and Vitamin E in Apparently Healthy Women[NCT00000479]Phase 339,876 participants (Actual)Interventional1992-09-30Completed
Automated Morphological Analysis of Meibomian Glands[NCT04052841]180 participants (Anticipated)Interventional2020-10-12Recruiting
Automatic Self Transcending Meditation (ASTM) Plus Treatment As Usual (TAU) Versus TAU Alone in Patients With Dry Eye Disease (DED): a Single Blind Randomized Controlled Longitudinal Study[NCT03087006]256 participants (Anticipated)Interventional2018-07-01Not yet recruiting
Study on the Effectiveness of Eye-drops Containing Cross-linked Hyaluronic Acid and Coenzyme Q10 in the Treatment of Patients With Mild to Moderate Dry Eye[NCT03074344]40 participants (Actual)Interventional2016-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Cancer, Excluding Nonmelanoma Skin Cancer

(NCT00000479)
Timeframe: Average follow-up 10.1 years

,,,
Interventionparticipants (Number)
Total invasive cancerCancer death
Aspirin + Vitamin E716152
Aspirin Only722132
Both Placebos706143
Vitamin E Only721156

Number of Participants With Major Cardiovascular Events (a Combined Endpoint of Nonfatal Myocardial Infarction, Nonfatal Stroke, and Total Cardiovascular Death)

(NCT00000479)
Timeframe: Average follow-up 10.1 years

,,,
InterventionParticipants (Number)
Major cardiovascular eventStrokeMyocardial infarctionCardiovascular death
Aspirin + Vitamin E23210810254
Aspirin Only2451139666
Both Placebos2721339974
Vitamin E Only2501339452

Trials

1 trial available for aspirin and Dry Eye Syndromes

ArticleYear
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003
Prevalence of dry eye syndrome among US women.
    American journal of ophthalmology, 2003, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Dry Eye Syndrome

2003

Other Studies

3 other studies available for aspirin and Dry Eye Syndromes

ArticleYear
The Effect of Low-Dose Aspirin on Dry Eye Parameters and Ocular Surface Disease Index Questionnaire.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2018, Volume: 34, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Corneal Diseases; Cross-Sectional Studies; Dose-Re

2018
Aspirin and dry eye?
    Ophthalmology, 2009, Volume: 116, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspir

2009
Case records of the Massachusetts General Hospital. Case 5-2009. A 47-year-old woman with a rash and numbness and pain in the legs.
    The New England journal of medicine, 2009, Feb-12, Volume: 360, Issue:7

    Topics: Antibodies, Antinuclear; Antirheumatic Agents; Aspirin; Biopsy; Diagnosis, Differential; Dry Eye Syn

2009