aspirin has been researched along with Diabetic Retinopathy in 83 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Early Treatment Diabetic Retinopathy Study (ETDRS), a multicenter randomized clinical trial, was designed to assess the effect of photocoagulation and aspirin on 3711 patients with mild to severe nonproliferative or early proliferative diabetic retinopathy." | 9.08 | Effects of aspirin on vitreous/preretinal hemorrhage in patients with diabetes mellitus. Early Treatment Diabetic Retinopathy Study report no. 20. ( Chew, EY; Ferris, FL; Klein, ML; Murphy, RP; Remaley, NA, 1995) |
| "The Early Treatment Diabetic Retinopathy Study (ETDRS), conducted at 22 clinical centers during the period 1980 to 1989, collected baseline data on C-peptide levels after ingestion of Sustacal in 582 patients with diabetes mellitus, prior to enrollment in the trial." | 9.07 | C-peptide and the classification of diabetes mellitus patients in the Early Treatment Diabetic Retinopathy Study. Report number 6. The ETDRS Research Group. ( Ewart, R; Kumar, D; Miller, D; Prior, MJ; Prout, T, 1993) |
| "Aspirin treatment did not alter the course of diabetic retinopathy in patients enrolled in the Early Treatment Diabetic Retinopathy Study (ETDRS)." | 9.07 | Effects of aspirin treatment on diabetic retinopathy. ETDRS report number 8. Early Treatment Diabetic Retinopathy Study Research Group. ( , 1991) |
| "The Early Treatment Diabetic Retinopathy Study, a randomized clinical trial supported by the National Eye Institute, was designed to assess the effect of photocoagulation and aspirin in 3711 patients with mild to severe nonproliferative or early proliferative diabetic retinopathy." | 9.07 | Aspirin effects on the development of cataracts in patients with diabetes mellitus. Early treatment diabetic retinopathy study report 16. ( Barton, FB; Burton, TC; Chew, EY; Ferris, FL; Remaley, NA; Williams, GA, 1992) |
| "This report presents information on the effects of aspirin on mortality, the occurrence of cardiovascular events, and the incidence of kidney disease in the patients enrolled in the Early Treatment Diabetic Retinopathy Study (ETDRS)." | 9.07 | Aspirin effects on mortality and morbidity in patients with diabetes mellitus. Early Treatment Diabetic Retinopathy Study report 14. ETDRS Investigators. ( , 1992) |
| " Gradings of baseline stereoscopic fluorescein angiograms of these eyes were used to examine relationships of angiographic characteristics with each other, with retinopathy severity level and macular edema status graded from color photographs, and with risk of progression from nonproliferative to proliferative retinopathy during 1 to 5 years of follow-up." | 9.07 | Fluorescein angiographic risk factors for progression of diabetic retinopathy. ETDRS report number 13. Early Treatment Diabetic Retinopathy Study Research Group. ( , 1991) |
| ", aspirin alone (330 mg 3 times daily) or in combination with dipyridamole (75 mg 3 times daily), was tested versus placebo in 475 patients with early diabetic retinopathy." | 9.06 | Effect of aspirin alone and aspirin plus dipyridamole in early diabetic retinopathy. A multicenter randomized controlled clinical trial. The DAMAD Study Group. ( , 1989) |
| "A description is given of the ophthalmological protocol of the DAMAD (aspirin and dipyridamole + Aspirin) controlled clinical trial in diabetic retinopathy." | 9.05 | [Controlled clinical trial of the effect of aspirin and aspirin + dipyridamole on the development of diabetic retinopathy. II. Ophthalmologic protocol]. ( , 1982) |
| " There have been both concerns that aspirin use might worsen diabetic retinopathy, as well as hopes that aspirin might be beneficial in treating it." | 8.81 | Aspirin in diabetic retinopathy. A systematic review. ( Bergerhoff, K; Clar, C; Richter, B, 2002) |
| "To determine the association between aspirin use and diabetic retinopathy (DR) among persons with diabetes, in a population-based, cross-sectional study." | 7.85 | Is aspirin associated with diabetic retinopathy? The Singapore Epidemiology of Eye Disease (SEED) study. ( Cheng, CY; Cheung, N; Cheung, YB; Chua, J; Mitchell, P; Shi, Y; Tan, G; Tham, YC; Wang, JJ; Wong, TY, 2017) |
| "The diabetic retinopathy is the leading cause of blindness in patients aged 20-65 years." | 5.35 | The effect of aspirin on hemorheological parameters of patients with diabetic retinopathy. ( Gaal, V; Juricskay, I; Kesmarky, G; Koltai, K; Toth, A; Vekasi, J, 2008) |
| "The ETDRS was a randomized trial investigating retinal photocoagulation and oral aspirin in diabetic retinopathy." | 5.11 | Classification of Farnsworth-Munsell 100-hue test results in the early treatment diabetic retinopathy study. ( Barton, FB; Fong, DS; Knatterud, GL, 2004) |
| "Follow-up study of the 214 surviving patients enrolled originally at the Johns Hopkins Clinical Center for the Early Treatment Diabetic Retinopathy Study (ETDRS), which was a clinical trial designed to evaluate the role of laser photocoagulation and aspirin treatment in patients with diabetic retinopathy." | 5.10 | The long-term effects of laser photocoagulation treatment in patients with diabetic retinopathy: the early treatment diabetic retinopathy follow-up study. ( Agrón, E; Chew, EY; Csaky, KG; Ferris, FL; Murphy, RP; Reed, GF; Schachat, AP; Thompson, DJ, 2003) |
| "A multicenter randomized clinical trial designed to assess the effect of photocoagulation and aspirin in patients with mild to severe nonproliferative or early proliferative diabetic retinopathy and/or macular edema." | 5.09 | Results after lens extraction in patients with diabetic retinopathy: early treatment diabetic retinopathy study report number 25. ( Benson, WE; Burton, TC; Chew, EY; Csaky, K; Ferris, FL; Lindley, AA; Remaley, NA; Williams, GA, 1999) |
| "Color vision function was measured at baseline in 2,701 patients enrolled in the Early Treatment Diabetic Retinopathy Study, a randomized trial investigating photocoagulation and aspirin in the treatment of diabetic retinopathy." | 5.09 | Impaired color vision associated with diabetic retinopathy: Early Treatment Diabetic Retinopathy Study Report No. 15. ( Barton, FB; Bresnick, GH; Fong, DS, 1999) |
| "The ETDRS was a randomized clinical trial investigating photocoagulation and aspirin in 3,711 persons with mild to severe nonproliferative or early proliferative diabetic retinopathy." | 5.09 | Causes of severe visual loss in the early treatment diabetic retinopathy study: ETDRS report no. 24. Early Treatment Diabetic Retinopathy Study Research Group. ( Chew, EY; Davis, MD; Ferris, FL; Fong, DS, 1999) |
| "A total of 109 eyes (in 96 persons) with SRF, defined as a mound or sheet of gray to white tissue beneath the retina at or near the center of the macula, were identified during the Early Treatment Diabetic Retinopathy Study, which is a randomized clinical trial of photocoagulation and aspirin treatment in patients with mild to severe nonproliferative or early proliferative diabetic retinopathy." | 5.08 | Subretinal fibrosis in diabetic macular edema. ETDRS report 23. Early Treatment Diabetic Retinopathy Study Research Group. ( Davis, MD; Ferris, FL; Fong, DS; Hubbard, LD; Myers, F; Segal, PP, 1997) |
| "The Early Treatment Diabetic Retinopathy Study (ETDRS), a multicenter randomized clinical trial, was designed to assess the effect of photocoagulation and aspirin on 3711 patients with mild to severe nonproliferative or early proliferative diabetic retinopathy." | 5.08 | Effects of aspirin on vitreous/preretinal hemorrhage in patients with diabetes mellitus. Early Treatment Diabetic Retinopathy Study report no. 20. ( Chew, EY; Ferris, FL; Klein, ML; Murphy, RP; Remaley, NA, 1995) |
| "This report presents information on the effects of aspirin on mortality, the occurrence of cardiovascular events, and the incidence of kidney disease in the patients enrolled in the Early Treatment Diabetic Retinopathy Study (ETDRS)." | 5.07 | Aspirin effects on mortality and morbidity in patients with diabetes mellitus. Early Treatment Diabetic Retinopathy Study report 14. ETDRS Investigators. ( , 1992) |
| "The Early Treatment Diabetic Retinopathy Study (ETDRS), conducted at 22 clinical centers during the period 1980 to 1989, collected baseline data on C-peptide levels after ingestion of Sustacal in 582 patients with diabetes mellitus, prior to enrollment in the trial." | 5.07 | C-peptide and the classification of diabetes mellitus patients in the Early Treatment Diabetic Retinopathy Study. Report number 6. The ETDRS Research Group. ( Ewart, R; Kumar, D; Miller, D; Prior, MJ; Prout, T, 1993) |
| "The Early Treatment Diabetic Retinopathy Study, a randomized clinical trial supported by the National Eye Institute, was designed to assess the effect of photocoagulation and aspirin in 3711 patients with mild to severe nonproliferative or early proliferative diabetic retinopathy." | 5.07 | Aspirin effects on the development of cataracts in patients with diabetes mellitus. Early treatment diabetic retinopathy study report 16. ( Barton, FB; Burton, TC; Chew, EY; Ferris, FL; Remaley, NA; Williams, GA, 1992) |
| "The Early Treatment Diabetic Retinopathy Study (ETDRS), a multicenter collaborative clinical trial supported by the National Eye Institute, was designed to assess whether argon laser photocoagulation or aspirin treatment can reduce the risk of visual loss or slow the progression of diabetic retinopathy in patients with mild-to-severe nonproliferative or early proliferative diabetic retinopathy." | 5.07 | Early Treatment Diabetic Retinopathy Study design and baseline patient characteristics. ETDRS report number 7. ( , 1991) |
| "Aspirin treatment did not alter the course of diabetic retinopathy in patients enrolled in the Early Treatment Diabetic Retinopathy Study (ETDRS)." | 5.07 | Effects of aspirin treatment on diabetic retinopathy. ETDRS report number 8. Early Treatment Diabetic Retinopathy Study Research Group. ( , 1991) |
| " Gradings of baseline stereoscopic fluorescein angiograms of these eyes were used to examine relationships of angiographic characteristics with each other, with retinopathy severity level and macular edema status graded from color photographs, and with risk of progression from nonproliferative to proliferative retinopathy during 1 to 5 years of follow-up." | 5.07 | Fluorescein angiographic risk factors for progression of diabetic retinopathy. ETDRS report number 13. Early Treatment Diabetic Retinopathy Study Research Group. ( , 1991) |
| ", aspirin alone (330 mg 3 times daily) or in combination with dipyridamole (75 mg 3 times daily), was tested versus placebo in 475 patients with early diabetic retinopathy." | 5.06 | Effect of aspirin alone and aspirin plus dipyridamole in early diabetic retinopathy. A multicenter randomized controlled clinical trial. The DAMAD Study Group. ( , 1989) |
| "Aspirin is recommended as cardiovascular disease prevention in patients with diabetes mellitus." | 4.84 | [Low-dose aspirin in patients with diabete melitus: risks and benefits regarding macro and microvascular complications]. ( Camargo, EG; Gross, JL; Lavinsky, J; Silveiro, SP; Weinert, LS, 2007) |
| " Increased leptin, dysregulation of adipocyte proteins, increased insulin resistance and C-reactive protein may be factors involved in the increased incidence of cardiovascular morbidity and mortality directly related to obesity." | 4.83 | Stroke prevention in diabetes and obesity. ( Govindarajan, G; Kurukulasuriya, LR; Sowers, J, 2006) |
| " This adherence was concerned particularly with co-medication in patients diagnosed with hypertension, aspirin prescription in elderly patients and the achievement of target lipid levels following the prescription of statins." | 3.79 | Sex-specific-differences in cardiometabolic risk in type 1 diabetes: a cross-sectional study. ( Hintersteiner, J; Johnson, J; Kamyar, MR; Kautzky, A; Kautzky-Willer, A; Lemmens-Gruber, R; Saukel, J; Stich, K, 2013) |
| "It has been previously reported that aspirin inhibited the development of diabetic retinopathy in diabetic animals, raising the possibility that anti-inflammatory drugs may have beneficial effects on diabetic retinopathy." | 3.74 | Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy. ( Hatala, DA; Howell, SJ; Huang, K; Kern, TS; Zheng, L, 2007) |
| "A nonselective inhibitor of cyclooxygenase (COX; high-dose aspirin) and a relatively selective inhibitor of inducible nitric oxide synthase (iNOS; aminoguanidine) have been found to inhibit development of diabetic retinopathy in animals, raising a possibility that NOS and COX play important roles in the development of retinopathy." | 3.72 | Interaction between NO and COX pathways in retinal cells exposed to elevated glucose and retina of diabetic rats. ( Du, Y; Kern, TS; Sarthy, VP, 2004) |
| "Observational data from the Early Treatment Diabetic Retinopathy Study." | 2.68 | Association of elevated serum lipid levels with retinal hard exudate in diabetic retinopathy. Early Treatment Diabetic Retinopathy Study (ETDRS) Report 22. ( Chantry, K; Chew, EY; Ferris, FL; Hoogwerf, BJ; Klein, ML; Miller, D; Murphy, RP; Remaley, NA, 1996) |
| "Accommodative amplitudes in Early Treatment Diabetic Retinopathy Study patients were lower than normal accommodative amplitudes." | 2.68 | Accommodative amplitudes in the Early Treatment Diabetic Retinopathy Study. ( Benson, WE; Braun, CI; Chew, EY; Ferris, FL; Remaley, NA, 1995) |
| "Pentosidine levels were significantly correlated with severity of retinopathy and neuropathy, but not nephropathy." | 2.68 | Effects of aspirin or basic amino acids on collagen cross-links and complications in NIDDM. ( Blanco, MC; Camejo, M; Contreras, I; Giansante, E; Gonzalez, F; Lopez, T; Martinez, N; Molina, M; Postalian, S; Reiser, KM; Sanchez, MR; Suarez, N, 1997) |
| "The Early Treatment Diabetic Retinopathy Study (ETDRS) enrolled 3711 patients with mild-to-severe nonproliferative or early proliferative diabetic retinopathy in both eyes." | 2.67 | Pars plana vitrectomy in the Early Treatment Diabetic Retinopathy Study. ETDRS report number 17. The Early Treatment Diabetic Retinopathy Study Research Group. ( Barton, FB; Chew, EY; Ferris, FL; Flynn, HW; Remaley, NA; Simons, BD, 1992) |
| "In the Early Treatment Diabetic Retinopathy Study, a randomized clinical trial sponsored by the National Eye Institute, one eye of each patient was assigned to early photocoagulation and the other to deferral of photocoagulation (i." | 2.67 | Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group. ( , 1991) |
| " Platelet survival in 27 insulin-dependent diabetic patients with severe retinopathy was studied in a double-blind cross-over trial using placebo, aspirin (990 mg/day) and a combination of dipyridamole (225 mg/day) with aspirin at two dosage levels (330 mg and 990 mg/day)." | 2.65 | Aspirin, dipyridamole and platelet survival in patients with diabetes mellitus. ( McNicol, GP; Paton, RC; Tindall, H, 1982) |
| "Careful counseling of women with diabetic nephropathy before pregnancy with estimation of the risk for the mother and fetus is important." | 2.48 | Obstetric nephrology: pregnancy in women with diabetic nephropathy--the role of antihypertensive treatment. ( Clausen, P; Damm, P; Feldt-Rasmussen, B; Mathiesen, ER; Ringholm, L, 2012) |
| "The diabetic retinopathy is the leading cause of blindness in patients aged 20-65 years." | 1.35 | The effect of aspirin on hemorheological parameters of patients with diabetic retinopathy. ( Gaal, V; Juricskay, I; Kesmarky, G; Koltai, K; Toth, A; Vekasi, J, 2008) |
| "An example from the Early Treatment Diabetic Retinopathy Study (ETDRS) is given." | 1.33 | Simultaneous group sequential analysis of rank-based and weighted Kaplan-Meier tests for paired censored survival data. ( Andrei, AC; Murray, S, 2005) |
| "Dyslipidemia is associated with macular exudates and vision loss." | 1.32 | Preventing diabetic retinopathy through control of systemic factors. ( Fong, D; Jain, A; Sarraf, D, 2003) |
| "During follow-up 56 recurrences occurred, making a total of 110 episodes of vitreous haemorrhage in 79 eyes of 54 patients." | 1.32 | Does cardiovascular therapy affect the onset and recurrence of preretinal and vitreous haemorrhage in diabetic eye disease? ( Banerjee, S; Denniston, AK; Dodson, PM; Gibson, JM, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (27.71) | 18.7374 |
| 1990's | 30 (36.14) | 18.2507 |
| 2000's | 22 (26.51) | 29.6817 |
| 2010's | 6 (7.23) | 24.3611 |
| 2020's | 2 (2.41) | 2.80 |
| Authors | Studies |
|---|---|
| Pafundi, PC | 1 |
| Galiero, R | 1 |
| Caturano, A | 1 |
| Acierno, C | 1 |
| de Sio, C | 1 |
| Vetrano, E | 1 |
| Nevola, R | 1 |
| Gelso, A | 1 |
| Bono, V | 1 |
| Costagliola, C | 1 |
| Marfella, R | 1 |
| Sardu, C | 1 |
| Rinaldi, L | 1 |
| Salvatore, T | 1 |
| Adinolfi, LE | 1 |
| Sasso, FC | 1 |
| Shi, Y | 1 |
| Tham, YC | 1 |
| Cheung, N | 1 |
| Chua, J | 1 |
| Tan, G | 1 |
| Mitchell, P | 1 |
| Wang, JJ | 1 |
| Cheung, YB | 1 |
| Cheng, CY | 1 |
| Wong, TY | 1 |
| Egan, AM | 1 |
| Brassill, MJ | 1 |
| Brosnan, E | 1 |
| Carmody, L | 1 |
| Clarke, H | 1 |
| Coogan Kelly, C | 1 |
| Culliney, L | 1 |
| Durkan, M | 1 |
| Fenlon, M | 1 |
| Ferry, P | 1 |
| Hanlon, G | 1 |
| Higgins, T | 1 |
| Hoashi, S | 1 |
| Khamis, A | 1 |
| Kinsley, B | 1 |
| Kinsley, T | 1 |
| Kirwan, B | 1 |
| Liew, A | 1 |
| McGurk, C | 1 |
| McHugh, C | 1 |
| Murphy, MS | 1 |
| Murphy, P | 1 |
| O'Halloran, D | 1 |
| O'Mahony, L | 1 |
| O'Sullivan, E | 1 |
| Nolan, M | 1 |
| Peter, M | 1 |
| Roberts, G | 1 |
| Smyth, A | 1 |
| Todd, M | 1 |
| Tuthill, A | 1 |
| Wan Mahmood, WA | 1 |
| Yousif, O | 1 |
| P Dunne, F | 1 |
| Kautzky-Willer, A | 1 |
| Stich, K | 1 |
| Hintersteiner, J | 1 |
| Kautzky, A | 1 |
| Kamyar, MR | 1 |
| Saukel, J | 1 |
| Johnson, J | 1 |
| Lemmens-Gruber, R | 1 |
| Gerhardinger, C | 2 |
| Dagher, Z | 2 |
| Sebastiani, P | 1 |
| Park, YS | 1 |
| Lorenzi, M | 2 |
| Brown, JS | 1 |
| Mahmoud, TH | 1 |
| De La Cruz, JP | 1 |
| Jebrouni, N | 1 |
| López-Villodres, JA | 1 |
| Muñoz-Marín, J | 1 |
| Guerrero, A | 2 |
| González-Correa, JA | 1 |
| Mathiesen, ER | 1 |
| Ringholm, L | 1 |
| Feldt-Rasmussen, B | 1 |
| Clausen, P | 1 |
| Damm, P | 1 |
| Bergerhoff, K | 1 |
| Clar, C | 1 |
| Richter, B | 1 |
| Fong, DS | 6 |
| Aiello, L | 2 |
| Gardner, TW | 2 |
| King, GL | 2 |
| Blankenship, G | 2 |
| Cavallerano, JD | 2 |
| Ferris, FL | 12 |
| Klein, R | 3 |
| Brown, AF | 1 |
| Mangione, CM | 1 |
| Saliba, D | 1 |
| Sarkisian, CA | 1 |
| Chew, EY | 10 |
| Csaky, KG | 1 |
| Murphy, RP | 4 |
| Agrón, E | 1 |
| Thompson, DJ | 1 |
| Reed, GF | 1 |
| Schachat, AP | 2 |
| Kohner, EM | 2 |
| Jain, A | 1 |
| Sarraf, D | 1 |
| Fong, D | 1 |
| Banerjee, S | 1 |
| Denniston, AK | 1 |
| Gibson, JM | 1 |
| Dodson, PM | 1 |
| Barton, FB | 4 |
| Knatterud, GL | 2 |
| Du, Y | 1 |
| Sarthy, VP | 1 |
| Kern, TS | 3 |
| Leal, EC | 1 |
| Santiago, AR | 1 |
| Ambrósio, AF | 1 |
| Andrei, AC | 1 |
| Murray, S | 1 |
| Sun, W | 1 |
| Hoehn, T | 1 |
| Kurukulasuriya, LR | 1 |
| Govindarajan, G | 1 |
| Sowers, J | 1 |
| Zheng, L | 1 |
| Howell, SJ | 1 |
| Hatala, DA | 1 |
| Huang, K | 1 |
| Camargo, EG | 1 |
| Gross, JL | 1 |
| Weinert, LS | 1 |
| Lavinsky, J | 1 |
| Silveiro, SP | 1 |
| Vekasi, J | 1 |
| Koltai, K | 1 |
| Gaal, V | 1 |
| Toth, A | 1 |
| Juricskay, I | 1 |
| Kesmarky, G | 1 |
| Valone, J | 1 |
| Waitzman, MB | 2 |
| Cornelius, LM | 1 |
| Evatt, BL | 1 |
| Kaplan, H | 1 |
| Cornelius, L | 1 |
| Evatt, B | 1 |
| Hunt, B | 1 |
| Cantrill, HL | 1 |
| Saldan, IR | 1 |
| Webster, J | 1 |
| Lewis, PJ | 1 |
| MacDermot, J | 1 |
| Hensby, CN | 1 |
| Porta, M | 1 |
| Tindall, H | 2 |
| Paton, RC | 2 |
| McNicol, GP | 2 |
| Rice, TA | 1 |
| Khosla, PK | 1 |
| Seth, V | 1 |
| Tiwari, HK | 1 |
| Saraya, AK | 1 |
| Zabel-Langhennig, R | 1 |
| Ruttmann, B | 1 |
| Schiele, I | 1 |
| Schäfer, W | 1 |
| Aisch, W | 1 |
| Zuzel, M | 1 |
| Moriarty, KT | 1 |
| Klein, ML | 2 |
| Remaley, NA | 6 |
| Patrono, C | 1 |
| Daví, G | 1 |
| Prior, MJ | 1 |
| Prout, T | 1 |
| Miller, D | 2 |
| Ewart, R | 1 |
| Kumar, D | 1 |
| Homberg, M | 1 |
| Tschöpe, D | 1 |
| Greber, H | 1 |
| Hackländer, T | 1 |
| Schwippert, B | 1 |
| Gries, FA | 1 |
| Mödder, U | 1 |
| Braun, CI | 1 |
| Benson, WE | 2 |
| Chantry, K | 1 |
| Hoogwerf, BJ | 1 |
| Feke, GT | 2 |
| Yoshida, A | 1 |
| Ogasawara, H | 1 |
| Konno, S | 1 |
| Goger, DG | 1 |
| Buzney, SM | 1 |
| McMeel, JW | 2 |
| Ferris, F | 1 |
| Contreras, I | 1 |
| Reiser, KM | 1 |
| Martinez, N | 1 |
| Giansante, E | 1 |
| Lopez, T | 1 |
| Suarez, N | 1 |
| Postalian, S | 1 |
| Molina, M | 1 |
| Gonzalez, F | 1 |
| Sanchez, MR | 1 |
| Camejo, M | 1 |
| Blanco, MC | 1 |
| Segal, PP | 1 |
| Myers, F | 1 |
| Hubbard, LD | 1 |
| Davis, MD | 3 |
| Fisher, MR | 1 |
| Gangnon, RE | 1 |
| Barton, F | 1 |
| Aiello, LM | 1 |
| Arango, JL | 1 |
| Pavan, PR | 1 |
| Lewis, L | 1 |
| Moss, SE | 1 |
| Klein, BE | 1 |
| Bresnick, GH | 1 |
| Lindley, AA | 1 |
| Burton, TC | 2 |
| Csaky, K | 1 |
| Williams, GA | 2 |
| Ong, HT | 1 |
| Engerman, RL | 1 |
| De La Cruz, P | 1 |
| Paniego, J | 1 |
| Arranz, I | 1 |
| Moreno, A | 1 |
| Sánchez De La Cuesta, F | 1 |
| Joussen, AM | 1 |
| Poulaki, V | 1 |
| Mitsiades, N | 1 |
| Kirchhof, B | 1 |
| Koizumi, K | 1 |
| Döhmen, S | 1 |
| Adamis, AP | 1 |
| Matsuo, T | 1 |
| Ohoki, Y | 1 |
| Colwell, JA | 2 |
| Halushka, PV | 1 |
| Sarji, K | 1 |
| Levine, J | 1 |
| Sagel, J | 1 |
| Nair, RM | 1 |
| Flynn, HW | 1 |
| Simons, BD | 1 |
| Ai, E | 1 |
| Patz, A | 2 |
| Smith, RE | 1 |
| Matsuyama, S | 1 |
| Finkelstein, D | 1 |
| Fine, SL | 1 |
| Tagawa, H | 1 |
| DiMinno, G | 1 |
| Silver, MJ | 1 |
| Cerbone, AM | 1 |
| Riccardi, G | 1 |
| Rivellese, A | 1 |
| Mancini, M | 1 |
| Amado, JA | 1 |
| Suárez, M | 1 |
| Richard, C | 1 |
| Sedano, MC | 1 |
| Hussey, HH | 1 |
| Kwaan, HC | 1 |
| Cruz, S | 1 |
| Suwanwela, N | 1 |
| Dobbie, JG | 1 |
| Powell, ED | 1 |
| Field, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Pulsatile IV Insulin Delivery on Diabetic Retinopathy[NCT00287651] | Phase 2/Phase 3 | 150 participants (Actual) | Interventional | 2005-11-30 | Terminated (stopped due to Administrative) | ||
| Identifying and Overcoming Barriers to Diabetes Management in the Elderly: An Intervention Study[NCT01480804] | 48 participants (Actual) | Interventional | 2006-11-30 | Completed | |||
| Identifying and Overcoming Barriers to Diabetes Management in the Elderly: A Cost-effective Intervention Study[NCT01486290] | 52 participants (Actual) | Interventional | 2007-07-31 | Completed | |||
| Testing the Effectiveness of Different Messaging Approaches to Increase Doctor Visits to Confirm or Exclude a Diagnosis of Prediabetes or Diabetes Amongst Individuals With Risk Factors for Diabetes: A Randomised, Controlled Trial[NCT05755555] | 5,000 participants (Actual) | Interventional | 2022-08-04 | Active, not recruiting | |||
| [NCT00000151] | Phase 3 | 0 participants | Interventional | 1979-12-31 | Completed | ||
| Aqueous Biomarker Levels in Diabetic Retinopathy and Diabetic Macular Edema[NCT05333055] | 150 participants (Anticipated) | Observational | 2022-04-11 | Not yet recruiting | |||
| Long-Term Efficacy and Safety of Intravitreal Aflibercept Injections for the Treatment of Diabetic Retinopathy for Subjects Who Completed the 2-Year PANORAMA Trial[NCT04708145] | Phase 4 | 150 participants (Anticipated) | Interventional | 2021-06-01 | Active, not recruiting | ||
| Intravitreal Aflibercept for Retinal Non-Perfusion in Proliferative Diabetic Retinopathy[NCT02863354] | Phase 2 | 43 participants (Actual) | Interventional | 2016-08-31 | Completed | ||
| Intravitreal Aflibercept as Indicated by Real-Time Objective Imaging to Achieve Diabetic Retinopathy Improvement[NCT03531294] | Phase 2 | 40 participants (Actual) | Interventional | 2018-05-23 | Completed | ||
| Slow-Release Dexamethasone in Reducing Proliferative Vitreoretinopathy After Vitreotomy in Proliferative Diabetic Retinopathy[NCT05415826] | 30 participants (Anticipated) | Interventional | 2022-06-15 | Not yet recruiting | |||
| A Randomized Clinical Trial of Intravitreal dexamethasOne Versus Bevacizumab in Aboriginal and Torres Strait Islander patientS With Diabetic Macular Oedema (The OASIS Study)[NCT04619303] | Phase 4 | 59 participants (Actual) | Interventional | 2017-02-07 | Completed | ||
| Early Laser Treatment for Diabetic Eye Disease in China: The PEARL Pilot Randomized Trial[NCT02956759] | 200 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | |||
| Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye[NCT01348672] | 381 participants (Anticipated) | Observational | 2012-03-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in area of retinal capillary non-perfusion outside of the macula from baseline to week 52 and week 100. (NCT02863354)
Timeframe: 52 weeks and 100 weeks
| Intervention | mm^2 (Mean) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | 240.472 | 387.204 |
| Q4WKS | 182.467 | 342.651 |
Change in area of retinal capillary non-perfusion within the macula compared to baseline, as assessed by ultrawide-field fluorescein angiogram from baseline to week 52 and week 100. (NCT02863354)
Timeframe: 52 weeks and 100 weeks
| Intervention | mm^2 (Mean) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | 0.217 | 0.940 |
| Q4WKS | 0.048 | 2.627 |
Change in area of total retinal capillary non-perfusion, as assessed by the central reading center, at week 52 and week 100 compared to baseline. (NCT02863354)
Timeframe: 52 weeks and 100 weeks
| Intervention | mm^2 (Mean) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | 66.752 | 245.694 |
| Q4WKS | -11.994 | 141.317 |
Mean change in Early Treatment of Diabetic Retinopathy Study Best Corrected Visual Acuity (ETDRS-BCVA) from baseline to week 52 and week 100. (NCT02863354)
Timeframe: 52 weeks and 100 weeks
| Intervention | ETDRS letters (Mean) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | 4.53 | 8.88 |
| Q4WKS | 4.26 | 4.06 |
Changes in self reported visual function utilizing the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25) from baseline to week 52 and week 100. The NEI VFQ is a validated measure of patient-reported visual function measured on a scale from 0 (worst function) to 100 (best function). (NCT02863354)
Timeframe: 52 weeks and 100 weeks
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | 2.23 | 8.82 |
| Q4WKS | 6.27 | 8.91 |
Mean change in central subfield thickness (CST) from baseline to week 52 and week 100 (NCT02863354)
Timeframe: 52 weeks and 100 weeks
| Intervention | micrometers (Mean) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | -20.813 | -23.313 |
| Q4WKS | -32.947 | -35.059 |
• Assess the safety and tolerability of IAI for the treatment of proliferative diabetic retinopathy by evaluating the incidence and severity of ocular and systemic adverse events through week 52 and week 100. (NCT02863354)
Timeframe: 52 and 100 weeks
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | 0 | 0 |
| Q4WKS | 0 | 0 |
Percentage of subjects treated with PRP or vitrectomy for progression of PDR from baseline to week 52 and week 100. (NCT02863354)
Timeframe: 52 Weeks and 100 Weeks
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | 0 | 0 |
| Q4WKS | 0 | 0 |
Percentage of subjects, at week 52 and week 100, who develop center-involving diabetic macular edema who did not have center-involving diabetic macular edema at baseline (NCT02863354)
Timeframe: 52 Weeks and 100 Weeks
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | 0 | 0 |
| Q4WKS | 0 | 0 |
Percentage of subjects who develop vitreous hemorrhage from baseline to week 52 and week 100. (NCT02863354)
Timeframe: 52 Weeks and 100 Weeks
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | 1 | 1 |
| Q4WKS | 2 | 4 |
Percentage of subjects with increased neovascularization from baseline to week 52 and week 100. (NCT02863354)
Timeframe: 52 Weeks and 100 Weeks
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | 0 | 0 |
| Q4WKS | 1 | 0 |
Percentage of subjects with neovascularization regression (reduced area of neovascularization) as measured by the central image reading center from baseline to week 52 and week 100. (NCT02863354)
Timeframe: 52 Weeks and 100 Weeks
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Week 52 | Week 100 | |
| Q12WKS | 18 | 15 |
| Q4WKS | 17 | 17 |
11 reviews available for aspirin and Diabetic Retinopathy
| Article | Year |
|---|---|
Obstetric nephrology: pregnancy in women with diabetic nephropathy--the role of antihypertensive treatment.
Topics: Albuminuria; Antihypertensive Agents; Aspirin; Counseling; Diabetes Mellitus, Type 1; Diabetes Melli | 2012 |
Aspirin in diabetic retinopathy. A systematic review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetic Retinopathy; Humans; Randomized Controlle | 2002 |
Old and new drug targets in diabetic retinopathy: from biochemical changes to inflammation and neurodegeneration.
Topics: Aldehyde Reductase; Animals; Antioxidants; Aspirin; Blood-Retinal Barrier; Diabetic Retinopathy; Gly | 2005 |
Stroke prevention in diabetes and obesity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atrial Fibrillation; Blood Glucose; Cardiovascular | 2006 |
[Low-dose aspirin in patients with diabete melitus: risks and benefits regarding macro and microvascular complications].
Topics: Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Angiopathies | 2007 |
Proliferative diabetic retinopathy and patient age: presentation, prognosis, and management.
Topics: Adolescent; Adult; Age Factors; Anticoagulants; Aspirin; Diabetes Mellitus, Type 1; Diabetic Retinop | 1984 |
The diabetic retinopathy study and the early treatment diabetic retinopathy study.
Topics: Adult; Aspirin; Clinical Trials as Topic; Diabetic Retinopathy; Edema; Follow-Up Studies; Humans; La | 1984 |
Antiplatelet agents in the prevention of diabetic vascular complications.
Topics: Aspirin; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Hum | 1993 |
Diabetic retinopathy treatment trials: a review.
Topics: Aspirin; Cyclooxygenase Inhibitors; Diabetic Retinopathy; Humans; Laser Coagulation; Randomized Cont | 1998 |
Diabetic retinopathy and lipid abnormalities.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Diabetic Retinopathy; Ex | 1997 |
Current management of diabetic retinopathy.
Topics: Aspirin; Diabetic Retinopathy; Humans; Laser Coagulation; Middle Aged; United States | 1992 |
29 trials available for aspirin and Diabetic Retinopathy
| Article | Year |
|---|---|
The long-term effects of laser photocoagulation treatment in patients with diabetic retinopathy: the early treatment diabetic retinopathy follow-up study.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cataract; Diabetic Retinopathy; Femal | 2003 |
Classification of Farnsworth-Munsell 100-hue test results in the early treatment diabetic retinopathy study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cluster Analysis; Color Perception Tests; C | 2004 |
The diabetic retinopathy study and the early treatment diabetic retinopathy study.
Topics: Adult; Aspirin; Clinical Trials as Topic; Diabetic Retinopathy; Edema; Follow-Up Studies; Humans; La | 1984 |
[Controlled clinical trial of the effect of aspirin and aspirin + dipyridamole on the development of diabetic retinopathy. II. Ophthalmologic protocol].
Topics: Aspirin; Clinical Trials as Topic; Diabetic Retinopathy; Dipyridamole; Drug Therapy, Combination; Fl | 1982 |
Aspirin, dipyridamole and platelet survival in patients with diabetes mellitus.
Topics: Adult; Aged; Aspirin; Blood Platelets; Cell Survival; Clinical Trials as Topic; Diabetic Retinopathy | 1982 |
[Controlled clinical trial of the effect of aspirin and aspirin + dipyridamole on the development of diabetic retinopathy. I. General protocol. From the DAMAD Study Group (author's transl)].
Topics: Adolescent; Adult; Aged; Aspirin; Blood Platelets; Clinical Trials as Topic; Diabetic Retinopathy; D | 1982 |
The early treatment diabetic retinopathy study.
Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Diabetic Retinopathy; Edema; Fluorescein | 1982 |
[5-year controlled therapy study on the prevention of diabetic angiopathy with the platelet-function inhibitor acetylsalicylic acid].
Topics: Adult; Arterial Occlusive Diseases; Aspirin; Brain Ischemia; Coronary Disease; Diabetic Angiopathies | 1982 |
Effects of aspirin on vitreous/preretinal hemorrhage in patients with diabetes mellitus. Early Treatment Diabetic Retinopathy Study report no. 20.
Topics: Adult; Aspirin; Diabetes Complications; Diabetic Retinopathy; Follow-Up Studies; Humans; Laser Coagu | 1995 |
C-peptide and the classification of diabetes mellitus patients in the Early Treatment Diabetic Retinopathy Study. Report number 6. The ETDRS Research Group.
Topics: Adult; Aspirin; C-Peptide; Combined Modality Therapy; Diabetes Mellitus; Diabetic Retinopathy; Discr | 1993 |
Accommodative amplitudes in the Early Treatment Diabetic Retinopathy Study.
Topics: Accommodation, Ocular; Adolescent; Adult; Age Factors; Aspirin; Diabetes Mellitus, Type 1; Diabetes | 1995 |
Association of elevated serum lipid levels with retinal hard exudate in diabetic retinopathy. Early Treatment Diabetic Retinopathy Study (ETDRS) Report 22.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Blood-Retinal Barrier; Capillary Permeability; Diabetes Co | 1996 |
Retinal blood flow increases following short-term aspirin usage in type I diabetics with no or minimal retinopathy.
Topics: Adult; Aspirin; Blood Flow Velocity; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetic Retinop | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Early photocoagulation in patients with either type I or type II diabetes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1996 |
Effects of aspirin or basic amino acids on collagen cross-links and complications in NIDDM.
Topics: Analysis of Variance; Arginine; Aspirin; Biopsy; Blood Glucose; Collagen; Cross-Linking Reagents; Cy | 1997 |
Subretinal fibrosis in diabetic macular edema. ETDRS report 23. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetic Retinopathy; Exudates and Transudates; Fi | 1997 |
Risk factors for high-risk proliferative diabetic retinopathy and severe visual loss: Early Treatment Diabetic Retinopathy Study Report #18.
Topics: Adolescent; Adult; Aged; Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neu | 1998 |
Causes of severe visual loss in the early treatment diabetic retinopathy study: ETDRS report no. 24. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Aspirin; Blindness; Diabetic Retinopathy; Female; Humans; Laser Coagulation; Male; Middle Aged; Reti | 1999 |
Diabetic retinopathy study results reveal combination therapy beneficial.
Topics: Aspirin; Combined Modality Therapy; Diabetes Complications; Diabetic Retinopathy; Humans; Light Coag | 1990 |
Impaired color vision associated with diabetic retinopathy: Early Treatment Diabetic Retinopathy Study Report No. 15.
Topics: Adolescent; Adult; Aged; Aging; Aspirin; Color; Color Perception; Diabetic Retinopathy; Discriminati | 1999 |
Results after lens extraction in patients with diabetic retinopathy: early treatment diabetic retinopathy study report number 25.
Topics: Aspirin; Cataract; Cataract Extraction; Diabetic Retinopathy; Disease Progression; Female; Humans; L | 1999 |
Pars plana vitrectomy in the Early Treatment Diabetic Retinopathy Study. ETDRS report number 17. The Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adult; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Humans; Laser Coagulation; Male; Mi | 1992 |
Aspirin effects on mortality and morbidity in patients with diabetes mellitus. Early Treatment Diabetic Retinopathy Study report 14. ETDRS Investigators.
Topics: Adolescent; Adult; Aged; Aspirin; Cerebrovascular Disorders; Diabetes Mellitus; Diabetic Retinopathy | 1992 |
Aspirin effects on the development of cataracts in patients with diabetes mellitus. Early treatment diabetic retinopathy study report 16.
Topics: Adult; Aspirin; Cataract; Diabetes Complications; Diabetic Retinopathy; Female; Follow-Up Studies; H | 1992 |
Early Treatment Diabetic Retinopathy Study design and baseline patient characteristics. ETDRS report number 7.
Topics: Adolescent; Adult; Aged; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Humans; Light Coa | 1991 |
Effects of aspirin treatment on diabetic retinopathy. ETDRS report number 8. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Humans; Life Tabl | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aneurysm; Aspirin; Diabetic Retinopathy; Female; Follow-Up Studies; Fundus | 1991 |
Fluorescein angiographic risk factors for progression of diabetic retinopathy. ETDRS report number 13. Early Treatment Diabetic Retinopathy Study Research Group.
Topics: Adolescent; Adult; Aged; Aspirin; Diabetic Retinopathy; Female; Fluorescein; Fluorescein Angiography | 1991 |
Effect of aspirin alone and aspirin plus dipyridamole in early diabetic retinopathy. A multicenter randomized controlled clinical trial. The DAMAD Study Group.
Topics: Adult; Aspirin; Blood Pressure; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellit | 1989 |
44 other studies available for aspirin and Diabetic Retinopathy
| Article | Year |
|---|---|
Aspirin in a diabetic retinopathy setting: Insights from NO BLIND study.
Topics: Aged; Aspirin; Cardiovascular Agents; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mel | 2020 |
Recommendations on the Clinical Use of Compound Danshen Dripping Pills.
Topics: Angina Pectoris; Aspirin; Camphanes; Clopidogrel; Coronary Disease; Diabetes Mellitus; Diabetic Neph | 2017 |
Is aspirin associated with diabetic retinopathy? The Singapore Epidemiology of Eye Disease (SEED) study.
Topics: Aspirin; Diabetic Retinopathy; Female; Humans; Male; Middle Aged; Regression Analysis; Singapore | 2017 |
An Irish National Diabetes in Pregnancy Audit: aiming for best outcomes for women with diabetes.
Topics: Abortion, Spontaneous; Adult; Aspirin; Cesarean Section; Clinical Audit; Delivery of Health Care; De | 2020 |
Sex-specific-differences in cardiometabolic risk in type 1 diabetes: a cross-sectional study.
Topics: Adult; Aspirin; Blood Pressure; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Complicat | 2013 |
The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy.
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Gene Expression Profiling; | 2009 |
Anticoagulation and clinically significant postoperative vitreous hemorrhage in diabetic vitrectomy.
Topics: Anticoagulants; Aspirin; Clopidogrel; Diabetic Retinopathy; Female; Humans; Incidence; Intraoperativ | 2011 |
Effects of terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, on retinal vascularity in diabetic rats.
Topics: Animals; Aspirin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Epoprostenol; Lipid Peroxid | 2012 |
Diabetic retinopathy.
Topics: Aspirin; Blood Pressure; Diabetic Retinopathy; Humans; Laser Coagulation; Quality Assurance, Health | 2003 |
Guidelines for improving the care of the older person with diabetes mellitus.
Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M | 2003 |
Guidelines for improving the care of the older person with diabetes mellitus.
Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M | 2003 |
Guidelines for improving the care of the older person with diabetes mellitus.
Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M | 2003 |
Guidelines for improving the care of the older person with diabetes mellitus.
Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M | 2003 |
Aspirin for diabetic retinopathy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetic Retinopathy; Humans; Platelet Aggregation | 2003 |
Preventing diabetic retinopathy through control of systemic factors.
Topics: Anticoagulants; Aspirin; Diabetic Angiopathies; Diabetic Retinopathy; Disease Progression; Female; G | 2003 |
Retinopathy in diabetes.
Topics: Aspirin; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans; Laser C | 2004 |
Does cardiovascular therapy affect the onset and recurrence of preretinal and vitreous haemorrhage in diabetic eye disease?
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular Agents; Cardiovascula | 2004 |
Interaction between NO and COX pathways in retinal cells exposed to elevated glucose and retina of diabetic rats.
Topics: Animals; Aspirin; Blotting, Western; Cattle; Cell Death; Cells, Cultured; Cyclooxygenase 2; Diabetes | 2004 |
Simultaneous group sequential analysis of rank-based and weighted Kaplan-Meier tests for paired censored survival data.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Computer Simulation; Data Interpretation, Statisti | 2005 |
Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effects.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blood Platelets; Clopidogrel; | 2005 |
Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Death; Diabete | 2007 |
The effect of aspirin on hemorheological parameters of patients with diabetic retinopathy.
Topics: Adult; Aged; Aspirin; Blood Viscosity; Diabetic Retinopathy; Erythrocyte Aggregation; Female; Fibrin | 2008 |
Treatment of canine spontaneous diabetes mellitus with aspirin.
Topics: Animals; Aspirin; Cyclic AMP; Cyclic GMP; Diabetes Mellitus; Diabetic Retinopathy; Disease Models, A | 1980 |
Aspirin and prostacyclin treatment of diabetic dogs.
Topics: Animals; Aspirin; Cyclic AMP; Diabetes Mellitus; Diabetic Retinopathy; Dog Diseases; Dogs; Epoproste | 1983 |
[Use of disaggregants in treating diabetic retinopathy].
Topics: Ascorbic Acid; Aspirin; Calcium Dobesilate; Diabetic Angiopathies; Diabetic Retinopathy; Dipyridamol | 1984 |
Forearm ischaemia as a test of prostacyclin production: studies in normal subjects and in patients with diabetes mellitus.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Glucose; Diabetic Retinopathy; Forearm; Gas Chro | 1981 |
Effect of aspirin on platelet aggregation in diabetes mellitus.
Topics: Arachidonic Acids; Aspirin; Collagen; Diabetes Mellitus; Diabetic Retinopathy; Humans; Middle Aged; | 1982 |
Platelet life-span in diabetics with and without retinopathy.
Topics: Adult; Aspirin; Blood Glucose; Blood Platelets; Cell Survival; Diabetes Complications; Diabetes Mell | 1981 |
Thrombolysis in patients with diabetes. Prophylaxis with aspirin should be considered.
Topics: Aspirin; Cardiovascular Diseases; Contraindications; Diabetic Retinopathy; Humans; Myocardial Infarc | 1995 |
[Optic neuropathy in type-1 diabetes and acetylsalicylic acid-refractory thrombocyte activation].
Topics: Adult; Aspirin; Chronic Disease; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Neuropa | 1993 |
The 14-year incidence of lower-extremity amputations in a diabetic population. The Wisconsin Epidemiologic Study of Diabetic Retinopathy.
Topics: Adolescent; Adult; Age Factors; Age of Onset; Aged; Amputation, Surgical; Aspirin; Blood Pressure; D | 1999 |
Aspirin in diabetes: beware of retinopathy.
Topics: Aspirin; Contraindications; Diabetic Angiopathies; Diabetic Retinopathy; Humans; Platelet Aggregatio | 2000 |
Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin.
Topics: Albumins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Blood Glucose; Diabet | 2001 |
Effect of aspirin on prostanoids and nitric oxide production in streptozotocin-diabetic rats with ischemic retinopathy.
Topics: Administration, Oral; Animals; Aorta; Aspirin; Diabetes Mellitus, Experimental; Diabetic Retinopathy | 2002 |
Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood-Retinal Barrier; Cell Adhesion; Cyc | 2002 |
[Significance of two concentrations of adenosine diphosphate inducing platelet aggregation in patients with diabetes mellitus (author's transl)].
Topics: Adenosine Diphosphate; Adult; Aged; Aging; Aspirin; Diabetes Mellitus; Diabetic Retinopathy; Female; | 1978 |
Altered platelet function in diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Cyclooxygenase | 1976 |
Can aspirin be used safely for patients with proliferative diabetic retinopathy?
Topics: Aspirin; Contraindications; Diabetic Retinopathy; Humans; Laser Therapy; Retinal Diseases; Vitreous | 1992 |
The ETDRS and Diabetes 2000.
Topics: Aspirin; Diabetic Retinopathy; Humans; Light Coagulation; Prognosis | 1991 |
[Prevention and early treatment of diabetic retinopathy].
Topics: Aspirin; Diabetic Retinopathy; Humans; Light Coagulation; Platelet Aggregation Inhibitors | 1990 |
The role of fluorescein angiography in national collaborative studies.
Topics: Aspirin; Choroid; Clinical Trials as Topic; Diabetic Retinopathy; Fluorescein Angiography; Forecasti | 1986 |
[Retinal circulatory changes in diabetic retinopathy].
Topics: Adult; Aspirin; Diabetic Retinopathy; Female; Humans; Light Coagulation; Male; Regional Blood Flow; | 1988 |
Platelet fibrinogen binding in diabetes mellitus. Differences between binding to platelets from nonretinopathic and retinopathic diabetic patients.
Topics: Adolescent; Adult; Apyrase; Aspirin; Blood Platelets; Diabetes Mellitus, Type 1; Diabetic Retinopath | 1986 |
Influence of acetylsalicylic acid on bleeding time and serum thromboxane B2 in diabetes mellitus type I.
Topics: Adolescent; Adult; Aspirin; Bleeding Time; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; | 1985 |
Editorial: Aspirin and diabetic retinopathy.
Topics: Aspirin; Diabetes Mellitus; Diabetic Retinopathy; Humans; Platelet Adhesiveness; Time Factors | 1974 |
Increased platelet aggregation in diabetes mellitus.
Topics: Adenosine Diphosphate; Aspirin; Blood Chemical Analysis; Blood Proteins; Creatinine; Diabetes Mellit | 1972 |
Studies on salicylates and complement in diabetes.
Topics: Adolescent; Adult; Aspirin; Complement System Proteins; Diabetes Mellitus; Diabetic Retinopathy; Fem | 1966 |