aspirin has been researched along with Diabetes Mellitus in 451 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
Excerpt | Relevance | Reference |
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"Irrespective of the presence of DM, CKD, and their combination, ticagrelor monotherapy reduced the risk of bleeding without a significant increase in ischaemic events compared with ticagrelor plus aspirin." | 9.51 | Ticagrelor monotherapy after PCI in patients with concomitant diabetes mellitus and chronic kidney disease: TWILIGHT DM-CKD. ( Angiolillo, DJ; Baber, U; Briguori, C; Cao, D; Cohen, DJ; Collier, T; Dangas, G; Dehghani, P; Dudek, D; Escaned, J; Gibson, M; Gil, R; Huber, K; Kaul, U; Kornowski, R; Krucoff, MW; Kunadian, V; Mehran, R; Mehta, S; Moliterno, DJ; Nicolas, J; Ohman, EM; Pivato, CA; Pocock, S; Sardella, G; Sartori, S; Sharma, SK; Shlofmitz, R; Weisz, G; Witzenbichler, B; Zhang, Z, 2022) |
"Aspirin does not have a large proportional effect on the risk of dementia." | 9.51 | Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial. ( Armitage, J; Barton, J; Bowman, L; Buck, G; Collins, R; Haynes, R; Mafham, M; Offer, A; Parish, S; Stevens, W; Wallendszus, K, 2022) |
"We sought to compare the biological efficacy of aspirin given once a day versus aspirin divided twice per day in a population of diabetic patients with non-ST elevation acute coronary syndrome (NSTE-ACS) as assessed by the thrombin generation test." | 9.41 | ImpaCt of aspirin regimen on THrombin generation in diabEtic patients with acute coronary syndrome: CARTHaGE-ACS trial. ( Addad, F; Baccouche, H; Bennour, E; Boussofara, A; Halima, AB; Kachboura, S; Kammoun, I; Kasbaoui, S; Laroussi, L; Marrakchi, S; Romdhane, NB; Triki, H; Zied, EH, 2021) |
"Compared with ticagrelor plus aspirin, the effect of ticagrelor monotherapy in reducing the risk of clinically relevant bleeding without any increase in ischemic events was consistent among patients with or without DM undergoing PCI." | 9.34 | Ticagrelor With or Without Aspirin in High-Risk Patients With Diabetes Mellitus Undergoing Percutaneous Coronary Intervention. ( Angiolillo, DJ; Baber, U; Briguori, C; Chandiramani, R; Cohen, DJ; Collier, T; Dangas, G; Dudek, D; Escaned, J; Gibson, CM; Huber, K; Kaul, U; Kornowski, R; Kunadian, V; Mehran, R; Mehta, SR; Oldroyd, KG; Pocock, S; Sardella, G; Sartori, S; Sharma, S; Shlofmitz, RA; Weisz, G; Witzenbichler, B; Ya-Ling, H, 2020) |
"In RE-DUAL PCI, 2,725 patients with atrial fibrillation (993 with diabetes) who had undergone PCI were assigned to warfarin triple therapy (warfarin, clopidogrel or ticagrelor, and aspirin) or dabigatran dual therapy (dabigatran 110 mg or 150 mg twice daily and clopidogrel or ticagrelor)." | 9.30 | Dabigatran Dual Therapy Versus Warfarin Triple Therapy Post-PCI in Patients With Atrial Fibrillation and Diabetes. ( Bhatt, DL; Cannon, CP; Hohnloser, SH; Kimura, T; Lip, GYH; Maeng, M; Miede, C; Nordaby, M; Oldgren, J; Steg, PG; Ten Berg, JM, 2019) |
" Aspirin use reduces the risk of occlusive vascular events but increases the risk of bleeding; the balance of benefits and hazards for the prevention of first cardiovascular events in patients with diabetes is unclear." | 9.27 | Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus. ( Adler, A; Armitage, J; Aung, T; Baigent, C; Barton, J; Bodansky, J; Bowman, L; Buck, G; Chen, F; Collins, R; Cox, J; Farmer, A; Haynes, R; Lay, M; Mafham, M; McPherson, R; Murawska, A; Murphy, K; Neil, A; Parish, S; Peto, R; Sammons, E; Simpson, D; Stevens, W; Wallendszus, K; Waters, E; Young, A, 2018) |
"There is a lack of evidence for pre-eclampsia prophylaxis with aspirin in women with pre-existing diabetes mellitus (DM)." | 9.22 | Aspirin for the prevention of pre-eclampsia in women with pre-existing diabetes: Systematic review. ( Alahakoon, TI; Cheung, NW; Haider, R; Jesudason, S; Lee, VW; Nolan, CJ; Padmanabhan, S; Peek, M; Simmons, D; Zen, M, 2022) |
"The role of aspirin in primary prevention of cardiovascular diseases (CVD) has been extensively evaluated; however, the results provided over the years have been controversial." | 9.22 | Aspirin for Primary Prevention of Cardiovascular Diseases: "WALTZ" with the Evidence. ( Dimitriadis, K; Lazarou, E; Soulaidopoulos, S; Tsioufis, K; Tsioufis, P, 2022) |
"A total of 14 464 patients (age, 60-85 years) with hypertension, dyslipidemia, and diabetes mellitus participated and were randomized into 2 treatment groups: 100 mg of aspirin or no aspirin." | 9.22 | Aspirin for Stroke Prevention in Elderly Patients With Vascular Risk Factors: Japanese Primary Prevention Project. ( Ando, K; Ikeda, Y; Ishizuka, N; Matsumoto, M; Minematsu, K; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Yamazaki, T; Yokoyama, K, 2016) |
"The goal of this study was to analyze the impact of dabigatran plasma concentrations, patient demographics, and aspirin (ASA) use on frequencies of ischemic strokes/systemic emboli and major bleeds in atrial fibrillation patients." | 9.19 | The effect of dabigatran plasma concentrations and patient characteristics on the frequency of ischemic stroke and major bleeding in atrial fibrillation patients: the RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy). ( Connolly, SJ; Eikelboom, JW; Ezekowitz, MD; Haertter, S; Lehr, T; Nehmiz, G; Reilly, PA; Wallentin, L; Wang, S; Yusuf, S, 2014) |
"Cilostazol increases circulating EPCs and decreases small-dense LDL in diabetic patients with cerebral ischemia." | 9.15 | Comparison of the effect of cilostazol with aspirin on circulating endothelial progenitor cells and small-dense LDL cholesterol in diabetic patients with cerebral ischemia: a randomized controlled pilot trial. ( Emoto, M; Fukumoto, S; Inaba, M; Koyama, H; Mima, Y; Nishizawa, Y; Shoji, T; Tanaka, S; Ueno, H, 2011) |
"The aim of this pilot study was to compare the effect of two different regimens of aspirin dosage on platelet of coronary artery disease (CAD) diabetic patients." | 9.14 | Antiplatelet effect of once- or twice-daily aspirin dosage in stable coronary artery disease patients with diabetes. ( Abderazek, F; Addad, F; Chakroun, T; Chouchene, S; Dridi, Z; Elalamy, I; Gamra, H; Gerotziafas, GT; Hassine, M; Hatmi, M, 2010) |
"We sought to evaluate the impact of cilostazol on neointimal hyperplasia after drug-eluting stent (DES) implantation in patients with diabetes mellitus (DM)." | 9.13 | Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Im ( Cho, YH; Choi, SW; Chun, KJ; Hong, MK; Kim, HS; Kim, JH; Kim, YH; Ko, JK; Lee, CW; Lee, JH; Lee, NH; Lee, SW; Park, DW; Park, JH; Park, SJ; Park, SW; Seong, IW; Yun, SC, 2008) |
"In this analysis, we aimed to compare the efficacy and safety of dual therapy (DT) with a non-vitamin K oral anticoagulant (NOAC) and an adenosine diphosphate receptor antagonist (P2Y12 inhibitor) vs triple therapy (TT) with aspirin, a P2Y12 inhibitor and a vitamin K antagonist for the treatment of diabetes mellitus (DM) patients with co-existing atrial fibrillation (AF) following percutaneous coronary intervention (PCI)." | 9.12 | Dual therapy with an oral non-vitamin K antagonist and a P2Y12 inhibitor vs triple therapy with aspirin, a P2Y12 inhibitor and a vitamin K antagonist for the treatment of diabetes mellitus patients with co-existing atrial fibrillation following percutaneo ( Wang, Q; Yang, K, 2021) |
"The Early Treatment Diabetic Retinopathy Study (ETDRS), conducted at 22 clinical centers during the period 1980 to 1989, collected baseline data on C-peptide levels after ingestion of Sustacal in 582 patients with diabetes mellitus, prior to enrollment in the trial." | 9.07 | C-peptide and the classification of diabetes mellitus patients in the Early Treatment Diabetic Retinopathy Study. Report number 6. The ETDRS Research Group. ( Ewart, R; Kumar, D; Miller, D; Prior, MJ; Prout, T, 1993) |
"This report presents information on the effects of aspirin on mortality, the occurrence of cardiovascular events, and the incidence of kidney disease in the patients enrolled in the Early Treatment Diabetic Retinopathy Study (ETDRS)." | 9.07 | Aspirin effects on mortality and morbidity in patients with diabetes mellitus. Early Treatment Diabetic Retinopathy Study report 14. ETDRS Investigators. ( , 1992) |
"To review the clinical evidence of the effect of aspirin as primary prevention for patients with diabetes mellitus and in healthy elderly." | 9.05 | Role of Aspirin for Primary Prevention in Persons with Diabetes Mellitus and in the Elderly. ( Baliga, RR; Patel, NJ, 2020) |
"The safety and efficacy of aspirin for the primary prevention of cardiovascular disease in patients with diabetes mellitus remains controversial." | 9.05 | Aspirin for primary prevention of cardiovascular outcomes in diabetes mellitus: An updated systematic review and meta-analysis. ( Ali, F; Kaluski, E; Khan, MU; Khan, SU; Krasuski, RA; Lone, AN; Mookadam, F; Shahzeb Khan, M; Talluri, S; Ul Abideen Asad, Z, 2020) |
"The role for aspirin in cardiovascular primary prevention remains controversial, with potential benefits limited by an increased bleeding risk." | 9.01 | Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. ( Roddick, AJ; Zheng, SL, 2019) |
"The benefits of aspirin therapy in reducing the subsequent risk of myocardial infarction, stroke and death is well documented in individuals with cardiovascular disease including those with diabetes mellitus (DM)." | 8.85 | Aspirin therapy and primary prevention of cardiovascular disease in diabetes mellitus. ( Soran, H; Williams, S; Younis, N, 2009) |
"The study pooled individual data from 2580 participants with nonvalvular AF who were prescribed aspirin in a multicenter trial (Atrial Fibrillation, Aspirin, Anticoagulation I study [AFASAK-1], AFASAK-2, European Atrial Fibrillation Trial, Primary Prevention of Arterial Thromboembolism in patients with nonrheumatic Atrial Fibrillation in primary care study, and Stroke Prevention and Atrial Fibrillation [SPAF]-III high risk or SPAF-III low risk)." | 8.82 | Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin. ( Boode, BS; Gage, BF; Hart, RG; Koudstaal, PJ; Pearce, L; Petersen, P; van Walraven, C, 2004) |
"The alterations in the metabolism of arachidonic acid to prostaglandin I2 (prostacyclin), a vasodilator antiaggregatory substance, and thromboxane A2, a vasoconstrictor proaggregatory substance, in diabetes mellitus are reviewed in this article." | 8.77 | Insulin and arachidonic acid metabolism in diabetes mellitus. ( Colwell, JA; Halushka, PV; Mayfield, R, 1985) |
"This study aimed to evaluate whether there is an association between the US Preventive Services Taskforce aspirin guideline hypertensive disorders of pregnancy and the rates of hypertensive disorders of pregnancy and preterm birth in individuals with pregestational diabetes mellitus." | 8.31 | Hypertensive disorders of pregnancy pre- and postaspirin guideline publication in individuals with pregestational diabetes mellitus. ( Allshouse, AA; Bruno, AM; Metz, TD; Theilen, LH, 2023) |
"To investigate the association between low-dose aspirin use for primary prevention and self-reported kidney stones prevalence in the 40-79 years old population." | 8.31 | Association of low-dose aspirin use for primary prevention with self-reported kidney stones prevalence: a cross-sectional study. ( Chen, Y; Huang, F; Li, Y; Yang, M, 2023) |
"Current guidelines recommend low-dose aspirin for preeclampsia prophylaxis in all women with pregestational (type one and type two) diabetes mellitus." | 8.12 | Associations between aspirin prophylaxis and fetal growth and preeclampsia in women with pregestational diabetes. ( Graham, DF; Shrestha Khatri, N; White, SW, 2022) |
"Patients with diabetes and no obstructive coronary artery disease (CAD) as assessed by coronary angiography (CAG) are frequently treated with aspirin and statins." | 8.12 | Statin but not aspirin treatment is associated with reduced cardiovascular risk in patients with diabetes without obstructive coronary artery disease: a cohort study from the Western Denmark Heart Registry. ( Bøtker, HE; Heide-Jørgensen, U; Maeng, M; Olesen, KKW; Sørensen, HT; Thim, T; Thomsen, RW, 2022) |
"Ticagrelor plus aspirin could reduce the risks of major adverse cardiac events in diabetic patients with stable coronary artery disease (SCD), and yet it also increases bleeding risk." | 8.02 | Cost-utility of ticagrelor plus aspirin in diabetic patients with stable coronary artery disease. ( Shi, L; Wu, B, 2021) |
"Aspirin is routinely prescribed in high-risk pregnancies to prevent pre-eclampsia; however, there is a paucity of data in women with pre-existing diabetes." | 8.02 | Aspirin and pre-eclampsia prevention in women with pre-existing diabetes: a retrospective study. ( Athayde, N; Cheung, NW; Inglis, E; Lah, S; Lee, V; Padmanabhan, S, 2021) |
"Whether or not the use of metformin decreases the risk of gastric adenocarcinoma is unclear." | 7.91 | Metformin use and risk of gastric adenocarcinoma in a Swedish population-based cohort study. ( Lagergren, J; Santoni, G; Xie, SH; Zheng, J, 2019) |
"High plasma level of HbA1c is involved in enhanced platelet aggregability in acute atherothrombotic stroke patients, and prestroke administration of aspirin may be beneficial to clinical outcomes." | 7.91 | Collagen-Induced Platelet Aggregates, Diabetes, and Aspirin Therapy Predict Clinical Outcomes in Acute Ischemic Stroke. ( Hagii, J; Harima, K; Honda, S; Kitajima, M; Metoki, H; Mikami, K; Osanai, T; Tomisawa, T; Urushizaka, M; Yasujima, M, 2019) |
"Our findings suggest that a cumulative aspirin dosage of more than 88,900 mg daily was associated with a reduced risk of breast cancer in women with diabetes." | 7.85 | Low-Dose Aspirin Reduces Breast Cancer Risk in Women with Diabetes: A Nationwide Retrospective Cohort Study in Taiwan. ( Chiou, JY; Huang, CN; Kornelius, E; Lai, YR; Lo, SC; Peng, CH; Yang, YS, 2017) |
"Seventy patients with stable coronary artery disease, supplemented with aspirin, participated in this pilot study." | 7.85 | MMP-2, MMP-9, and TIMP-4 and Response to Aspirin in Diabetic and Nondiabetic Patients with Stable Coronary Artery Disease: A Pilot Study. ( Bil-Lula, I; Gąsior, M; Kaczmarski, J; Kuliczkowski, W; Mysiak, A; Negrusz-Kawecka, M; Radomski, M; Urbaniak, J, 2017) |
"The combined use of aspirin and oral anticoagulant therapy in patients with atrial fibrillation (AF) and stable coronary artery disease (CAD) has been questioned due to an increased risk of major bleeding with little to no benefit in preventing ischemic events." | 7.85 | Combined aspirin and anticoagulant therapy in patients with atrial fibrillation. ( Eckman, MH; So, CH, 2017) |
" Diabetes mellitus and current smoker status were independent factors related to reactivity to clopidogrel." | 7.83 | Influence of Diabetes Mellitus and Cigarette Smoking on Variability of the Clopidogrel-Induced Antiplatelet Effect and Efficacy of Active Management of the Target P2Y12 Reaction Unit Range in Patients Undergoing Neurointerventional Procedures. ( Hironaka, Y; Kichikawa, K; Motoyama, Y; Nakagawa, I; Nakase, H; Park, HS; Takayama, K; Wada, T; Yokoyama, S, 2016) |
"To evaluate the efficacy and safety of aspirin usage for coronary heart disease (CHD) primary prevention in patients with dyslipidemia." | 7.83 | Effects of low-dose aspirin in subjects with dyslipidemia. ( Chen, J; Lou, G; Xia, Y, 2016) |
"To evaluate whether aspirin can reduce the risk of colorectal cancer in people with diabetes." | 7.81 | Can aspirin reduce the risk of colorectal cancer in people with diabetes? A population-based cohort study. ( Lai, MS; Lin, CC; Shau, WY, 2015) |
"The US Preventive Services Task Force recommends aspirin use for men aged 45 to 79, when the potential benefit of preventing myocardial infarctions outweighs the potential harm of gastrointestinal hemorrhage." | 7.81 | Aspirin Use for the Primary Prevention of Myocardial Infarction Among Men in North Carolina, 2013. ( Fleming, E; Perry, GS; Tchwenko, S, 2015) |
"Use of warfarin, low GCS score, opening to ventricle, older age, accompanying diabetes, and/or hypertension were worse prognostic factors." | 7.80 | Intracranial hemorrhages related with warfarin use and comparison of warfarin and acetylsalicylic acid. ( Beckmann, Y; Ciftçi, Y; Seçil, Y; Tokuçoğlu, F, 2014) |
"Long-term administration of low-dose aspirin (LDA) is associated with a greater risk of adverse events, including gastroduodenal ulcers." | 7.79 | Low-dose aspirin-associated upper gastric and duodenal ulcers in Japanese patients with no previous history of peptic ulcers. ( Funaki, Y; Iida, A; Ito, Y; Kasugai, K; Kawamura, N; Mizuno, M; Ogasawara, N; Sasaki, M, 2013) |
"The widespread use of aspirin-driven vascular prevention strategies does not impede the occurrence of first and recurrent ischemic strokes in numerous subjects." | 7.78 | Ischemic stroke in patients receiving aspirin. ( Ameriso, S; Ameriso, SF; Povedano, GP; Pujol Lereis, VA, 2012) |
"Exploration of atherogenic diet-induced diabetes mellitus and the evaluation of antidiabetic potential of aspirin were carried out in this study." | 7.77 | The effect of aspirin on atherogenic diet-induced diabetes mellitus. ( Kumar, A; Parmar, HS; Sethi, A, 2011) |
"There have been no randomized trials of cardioprotective therapy after acute myocardial infarction in patients with chronic kidney disease who should be largely eligible for aspirin (acetylsalicylic acid; ASA) and beta-blockers (BB) as a base of therapy." | 7.71 | Benefits of aspirin and beta-blockade after myocardial infarction in patients with chronic kidney disease. ( Borzak, S; Garg, M; Hudson, MP; Manley, HJ; McCullough, PA; Sandberg, KR, 2002) |
"The results of two large independent studies involving a combined total of 776 patients treated in hospital with a discharge diagnosis of acute myocardial infarction and 13,898 patients with other discharge diagnoses showed a negative association between regular aspirin intake and non-fatal myocardial infarction." | 7.65 | Regular aspirin intake and acute myocardial infarction. ( , 1974) |
" However, the effects of EV-077 on pharmacodynamic (PD) profiles in patients with DM and coronary artery disease (CAD) while on antiplatelet therapy is poorly explored and represented the aim of this in vitro pilot investigation." | 6.79 | Pharmacodynamic effects of EV-077 in patients with diabetes mellitus and coronary artery disease on aspirin or clopidogrel monotherapy: results of an in vitro pilot investigation. ( Angiolillo, DJ; Bender, N; Darlington, A; Desai, B; Franchi, F; Muñiz-Lozano, A; Patel, R; Rollini, F; Sakariassen, KS; Tello-Montoliu, A; Wilson, RE, 2014) |
"Cilostazol is a platelet inhibitor which when added to aspirin and clopidogrel has shown to reduce the risk of recurrent ischaemic events without an increase in bleeding." | 6.76 | Impact of adjunctive cilostazol therapy on platelet function profiles in patients with and without diabetes mellitus on aspirin and clopidogrel therapy. ( Angiolillo, DJ; Bass, TA; Box, LC; Capodanno, D; Capranzano, P; Charlton, RK; Darlington, A; Desai, B; Dharmashankar, K; Ferreiro, JL; Guzman, LA; Sumner, S; Ueno, M; Zenni, M, 2011) |
"In this prospective, open-label, multi-centre, 2 × 2 factorial, randomized, controlled study, 1,800 patients with diabetes mellitus and multi-vessel disease (inclusion criteria similar to FREEDOM trial) with indication for coronary revascularization will be randomly assigned to Supraflex Cruz or Xience stents and also to ticagrelor- or prasugrel- based antiplatelet strategies." | 5.69 | Rationale and design of the TUXEDO-2 India study: Ultra-Thin strUt Supraflex Cruz versus XiencE in a Diabetic pOpulation with multi-vessel disease-2. ( Abhaichand, R; Agrawal, DK; Arambam, P; Bangalore, S; Banker, D; Chandra, S; Garg, R; Kaul, U; Khan, A; Koduganti, SC; Mody, R; Moorthy, N; Parida, AK; Reddy, KMK; Sarma, PR; Sharma, R; Sinha, SK, 2023) |
"Irrespective of the presence of DM, CKD, and their combination, ticagrelor monotherapy reduced the risk of bleeding without a significant increase in ischaemic events compared with ticagrelor plus aspirin." | 5.51 | Ticagrelor monotherapy after PCI in patients with concomitant diabetes mellitus and chronic kidney disease: TWILIGHT DM-CKD. ( Angiolillo, DJ; Baber, U; Briguori, C; Cao, D; Cohen, DJ; Collier, T; Dangas, G; Dehghani, P; Dudek, D; Escaned, J; Gibson, M; Gil, R; Huber, K; Kaul, U; Kornowski, R; Krucoff, MW; Kunadian, V; Mehran, R; Mehta, S; Moliterno, DJ; Nicolas, J; Ohman, EM; Pivato, CA; Pocock, S; Sardella, G; Sartori, S; Sharma, SK; Shlofmitz, R; Weisz, G; Witzenbichler, B; Zhang, Z, 2022) |
"Aspirin does not have a large proportional effect on the risk of dementia." | 5.51 | Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial. ( Armitage, J; Barton, J; Bowman, L; Buck, G; Collins, R; Haynes, R; Mafham, M; Offer, A; Parish, S; Stevens, W; Wallendszus, K, 2022) |
"Diabetes mellitus has been associated with a substantially increased risk of both first and recurrent atherothrombotic events, which makes aspirin therapy of potential value in these subjects." | 5.43 | Aspirin for Primary Cardiovascular Risk Prevention and Beyond in Diabetes Mellitus. ( Angiolillo, DJ; Capodanno, D, 2016) |
"Evidence regarding using acetylsalicylic acid (aspirin) for the prevention of cardiovascular (CV) events in patients with diabetes mellitus (DM) is inconsistent." | 5.41 | Acetylsalicylic Acid (Aspirin) for Primary Prevention of Cardiovascular Events in Patients with Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ( Cheema, AN; Eckstein, J; Lam, A; Liu, S, 2023) |
"We sought to compare the biological efficacy of aspirin given once a day versus aspirin divided twice per day in a population of diabetic patients with non-ST elevation acute coronary syndrome (NSTE-ACS) as assessed by the thrombin generation test." | 5.41 | ImpaCt of aspirin regimen on THrombin generation in diabEtic patients with acute coronary syndrome: CARTHaGE-ACS trial. ( Addad, F; Baccouche, H; Bennour, E; Boussofara, A; Halima, AB; Kachboura, S; Kammoun, I; Kasbaoui, S; Laroussi, L; Marrakchi, S; Romdhane, NB; Triki, H; Zied, EH, 2021) |
"5 mg rivaroxaban twice daily and 100 mg aspirin once daily compared with 100 mg aspirin once daily reduces major adverse cardiovascular (CV) events in patients with chronic coronary artery disease (CAD) or peripheral artery disease (PAD)." | 5.41 | Mortality Benefit of Rivaroxaban Plus Aspirin in Patients With Chronic Coronary or Peripheral Artery Disease. ( Anand, SS; Avezum, A; Berkowitz, SD; Bhatt, DL; Bosch, J; Branch, KRH; Connolly, SJ; Dagenais, GR; Eikelboom, JW; Félix, C; Fox, KAA; Guzik, TJ; Hart, RG; Maggioni, AP; Muehlhofer, E; Sharma, M; Shestakovska, O; Yusuf, S, 2021) |
"Diabetes mellitus is an independent predictor of adverse clinical events after drug-eluting stent implantation." | 5.39 | Clinical efficacy and safety of biodegradable polymer-based sirolimus-eluting stents in patients with diabetes mellitus insight from the 4-year results of the create study. ( Chen, X; Han, Y; Jiang, T; Jing, Q; Li, Y; Liu, H; Ma, Y; Wang, G; Wang, S; Wang, X; Yan, G; Yang, L; Zhang, L; Zhu, G, 2013) |
"5 mg twice daily) plus aspirin (100 mg daily) versus placebo plus aspirin in patients with diabetes mellitus versus without diabetes mellitus in preventing major vascular events." | 5.34 | Role of Combination Antiplatelet and Anticoagulation Therapy in Diabetes Mellitus and Cardiovascular Disease: Insights From the COMPASS Trial. ( Anand, SS; Avezum, A; Berkowitz, SD; Bhatt, DL; Bosch, J; Branch, KRH; Connolly, SJ; Diaz, R; Eikelboom, JW; Fox, KAA; Lewis, BS; Maggioni, AP; Probstfield, J; Ryden, L; Shestakovska, O; Steg, PG; Szarek, M; Verma, S; Widimský, P; Yusuf, S, 2020) |
"Compared with ticagrelor plus aspirin, the effect of ticagrelor monotherapy in reducing the risk of clinically relevant bleeding without any increase in ischemic events was consistent among patients with or without DM undergoing PCI." | 5.34 | Ticagrelor With or Without Aspirin in High-Risk Patients With Diabetes Mellitus Undergoing Percutaneous Coronary Intervention. ( Angiolillo, DJ; Baber, U; Briguori, C; Chandiramani, R; Cohen, DJ; Collier, T; Dangas, G; Dudek, D; Escaned, J; Gibson, CM; Huber, K; Kaul, U; Kornowski, R; Kunadian, V; Mehran, R; Mehta, SR; Oldroyd, KG; Pocock, S; Sardella, G; Sartori, S; Sharma, S; Shlofmitz, RA; Weisz, G; Witzenbichler, B; Ya-Ling, H, 2020) |
"Aspirin non-response was defined as: 1) slope steeper than 12%/min in AA-aggregations, and 2) by closure time shorter than 170 s in PFA-100." | 5.33 | Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients. ( Backman, JT; Kankuri, E; Karhunen, PJ; Lassila, R; Lepäntalo, A; Mikkelsson, J; Reséndiz, JC; Viiri, L, 2006) |
"In RE-DUAL PCI, 2,725 patients with atrial fibrillation (993 with diabetes) who had undergone PCI were assigned to warfarin triple therapy (warfarin, clopidogrel or ticagrelor, and aspirin) or dabigatran dual therapy (dabigatran 110 mg or 150 mg twice daily and clopidogrel or ticagrelor)." | 5.30 | Dabigatran Dual Therapy Versus Warfarin Triple Therapy Post-PCI in Patients With Atrial Fibrillation and Diabetes. ( Bhatt, DL; Cannon, CP; Hohnloser, SH; Kimura, T; Lip, GYH; Maeng, M; Miede, C; Nordaby, M; Oldgren, J; Steg, PG; Ten Berg, JM, 2019) |
" Aspirin use reduces the risk of occlusive vascular events but increases the risk of bleeding; the balance of benefits and hazards for the prevention of first cardiovascular events in patients with diabetes is unclear." | 5.27 | Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus. ( Adler, A; Armitage, J; Aung, T; Baigent, C; Barton, J; Bodansky, J; Bowman, L; Buck, G; Chen, F; Collins, R; Cox, J; Farmer, A; Haynes, R; Lay, M; Mafham, M; McPherson, R; Murawska, A; Murphy, K; Neil, A; Parish, S; Peto, R; Sammons, E; Simpson, D; Stevens, W; Wallendszus, K; Waters, E; Young, A, 2018) |
" One-step extraction of UTXB2 with an octadecylsilyl-silica column was sufficient as pretreatment for TXB2 radioimmunoassay because recovery of UTXB2 was good, the eluate was parallel with the dose-response curve, and the value coincided with that obtained by the conventional method." | 5.27 | Increased thromboxane B2 excretion in diabetes mellitus. ( Inaba, M; Ishii, J; Katayama, S; Kawazu, S; Maruno, Y; Omoto, A, 1987) |
" In the uncommon occurrence of asthma and diabetes in the same patient, insulin dosage should be considered as a factor in all such asthmatics who do not respond well to conventional therapy." | 5.26 | Diabetes mellitus and insulin in an aspirin sensitive asthmatic. ( Caplin, I, 1976) |
"There is a lack of evidence for pre-eclampsia prophylaxis with aspirin in women with pre-existing diabetes mellitus (DM)." | 5.22 | Aspirin for the prevention of pre-eclampsia in women with pre-existing diabetes: Systematic review. ( Alahakoon, TI; Cheung, NW; Haider, R; Jesudason, S; Lee, VW; Nolan, CJ; Padmanabhan, S; Peek, M; Simmons, D; Zen, M, 2022) |
"The role of aspirin in primary prevention of cardiovascular diseases (CVD) has been extensively evaluated; however, the results provided over the years have been controversial." | 5.22 | Aspirin for Primary Prevention of Cardiovascular Diseases: "WALTZ" with the Evidence. ( Dimitriadis, K; Lazarou, E; Soulaidopoulos, S; Tsioufis, K; Tsioufis, P, 2022) |
" The prediction rule assigned 1 point each for myocardial infarction at presentation, prior myocardial infarction or PCI, diabetes, stent diameter less than 3 mm, smoking, and paclitaxel-eluting stent; 2 points each for history of congestive heart failure/low ejection fraction and vein graft intervention; -1 point for age 65 to younger than 75 years; and -2 points for age 75 years or older." | 5.22 | Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention. ( Apruzzese, PK; Camenzind, E; Cohen, DJ; Cutlip, DE; Gershlick, AH; Kereiakes, DJ; Massaro, JM; Mauri, L; Normand, SL; Rinaldi, MJ; Secemsky, EA; Song, Y; Spertus, JA; Steg, PG; Wijns, W; Yeh, RW, 2016) |
"A total of 14 464 patients (age, 60-85 years) with hypertension, dyslipidemia, and diabetes mellitus participated and were randomized into 2 treatment groups: 100 mg of aspirin or no aspirin." | 5.22 | Aspirin for Stroke Prevention in Elderly Patients With Vascular Risk Factors: Japanese Primary Prevention Project. ( Ando, K; Ikeda, Y; Ishizuka, N; Matsumoto, M; Minematsu, K; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Yamazaki, T; Yokoyama, K, 2016) |
"The goal of this study was to analyze the impact of dabigatran plasma concentrations, patient demographics, and aspirin (ASA) use on frequencies of ischemic strokes/systemic emboli and major bleeds in atrial fibrillation patients." | 5.19 | The effect of dabigatran plasma concentrations and patient characteristics on the frequency of ischemic stroke and major bleeding in atrial fibrillation patients: the RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy). ( Connolly, SJ; Eikelboom, JW; Ezekowitz, MD; Haertter, S; Lehr, T; Nehmiz, G; Reilly, PA; Wallentin, L; Wang, S; Yusuf, S, 2014) |
"Once-daily, low-dose aspirin did not significantly reduce the risk of the composite outcome of cardiovascular death, nonfatal stroke, and nonfatal myocardial infarction among Japanese patients 60 years or older with atherosclerotic risk factors." | 5.19 | Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial. ( Ando, K; Ikeda, Y; Ishizuka, N; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Yamazaki, T; Yokoyama, K, 2014) |
"Cilostazol increases circulating EPCs and decreases small-dense LDL in diabetic patients with cerebral ischemia." | 5.15 | Comparison of the effect of cilostazol with aspirin on circulating endothelial progenitor cells and small-dense LDL cholesterol in diabetic patients with cerebral ischemia: a randomized controlled pilot trial. ( Emoto, M; Fukumoto, S; Inaba, M; Koyama, H; Mima, Y; Nishizawa, Y; Shoji, T; Tanaka, S; Ueno, H, 2011) |
"The Japanese Primary Prevention Project (JPPP) is a multicenter, open-label, randomized, parallel-group trial that is evaluating primary prevention with low-dose aspirin in Japanese patients aged 60 to 85 years with hypertension, dyslipidemia, or diabetes mellitus." | 5.14 | Rationale, design, and baseline data of the Japanese Primary Prevention Project (JPPP)-a randomized, open-label, controlled trial of aspirin versus no aspirin in patients with multiple risk factors for vascular events. ( Ando, K; Goto, Y; Ikeda, Y; Ishizuka, N; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Yamada, N; Yamazaki, T; Yokoyama, K, 2010) |
"The aim of this pilot study was to compare the effect of two different regimens of aspirin dosage on platelet of coronary artery disease (CAD) diabetic patients." | 5.14 | Antiplatelet effect of once- or twice-daily aspirin dosage in stable coronary artery disease patients with diabetes. ( Abderazek, F; Addad, F; Chakroun, T; Chouchene, S; Dridi, Z; Elalamy, I; Gamra, H; Gerotziafas, GT; Hassine, M; Hatmi, M, 2010) |
"We sought to evaluate the impact of cilostazol on neointimal hyperplasia after drug-eluting stent (DES) implantation in patients with diabetes mellitus (DM)." | 5.13 | Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Im ( Cho, YH; Choi, SW; Chun, KJ; Hong, MK; Kim, HS; Kim, JH; Kim, YH; Ko, JK; Lee, CW; Lee, JH; Lee, NH; Lee, SW; Park, DW; Park, JH; Park, SJ; Park, SW; Seong, IW; Yun, SC, 2008) |
"In this analysis, we aimed to compare the efficacy and safety of dual therapy (DT) with a non-vitamin K oral anticoagulant (NOAC) and an adenosine diphosphate receptor antagonist (P2Y12 inhibitor) vs triple therapy (TT) with aspirin, a P2Y12 inhibitor and a vitamin K antagonist for the treatment of diabetes mellitus (DM) patients with co-existing atrial fibrillation (AF) following percutaneous coronary intervention (PCI)." | 5.12 | Dual therapy with an oral non-vitamin K antagonist and a P2Y12 inhibitor vs triple therapy with aspirin, a P2Y12 inhibitor and a vitamin K antagonist for the treatment of diabetes mellitus patients with co-existing atrial fibrillation following percutaneo ( Wang, Q; Yang, K, 2021) |
"0001) after adjustment for age, aspirin use, smoking, physical activity, body mass index, and history of angina, hypertension, and high cholesterol." | 5.09 | Alcohol consumption and risk of coronary heart disease by diabetes status. ( Ajani, UA; Buring, JE; Gaziano, JM; Hennekens, CH; Liu, S; Lotufo, PA; Manson, JE, 2000) |
"The Early Treatment Diabetic Retinopathy Study (ETDRS), conducted at 22 clinical centers during the period 1980 to 1989, collected baseline data on C-peptide levels after ingestion of Sustacal in 582 patients with diabetes mellitus, prior to enrollment in the trial." | 5.07 | C-peptide and the classification of diabetes mellitus patients in the Early Treatment Diabetic Retinopathy Study. Report number 6. The ETDRS Research Group. ( Ewart, R; Kumar, D; Miller, D; Prior, MJ; Prout, T, 1993) |
"This report presents information on the effects of aspirin on mortality, the occurrence of cardiovascular events, and the incidence of kidney disease in the patients enrolled in the Early Treatment Diabetic Retinopathy Study (ETDRS)." | 5.07 | Aspirin effects on mortality and morbidity in patients with diabetes mellitus. Early Treatment Diabetic Retinopathy Study report 14. ETDRS Investigators. ( , 1992) |
"To review the clinical evidence of the effect of aspirin as primary prevention for patients with diabetes mellitus and in healthy elderly." | 5.05 | Role of Aspirin for Primary Prevention in Persons with Diabetes Mellitus and in the Elderly. ( Baliga, RR; Patel, NJ, 2020) |
"The safety and efficacy of aspirin for the primary prevention of cardiovascular disease in patients with diabetes mellitus remains controversial." | 5.05 | Aspirin for primary prevention of cardiovascular outcomes in diabetes mellitus: An updated systematic review and meta-analysis. ( Ali, F; Kaluski, E; Khan, MU; Khan, SU; Krasuski, RA; Lone, AN; Mookadam, F; Shahzeb Khan, M; Talluri, S; Ul Abideen Asad, Z, 2020) |
"The blocking effects of aspirin, chlorpheniramine, and cimetidine were tested against the flush provoked by alcohol in twenty-four chlorpropamide-treated patients with non-insulin-dependent diabetes mellitus." | 5.05 | Blockade of chlorpropamide alcohol flush by aspirin. ( Jefferys, DB; Keen, H; Strakosch, CR, 1980) |
"The role for aspirin in cardiovascular primary prevention remains controversial, with potential benefits limited by an increased bleeding risk." | 5.01 | Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis. ( Roddick, AJ; Zheng, SL, 2019) |
"Aspirin reduces the risk of nonfatal myocardial infarction and stroke, and the risk of colorectal cancer." | 4.95 | Aspirin for Primary Prevention. ( Owens, DK; Richman, IB, 2017) |
"A literature search was conducted using the terms cardiovascular disease, aspirin, diabetes mellitus to identify trials of patients with diabetes who received aspirin for primary prevention of CVD." | 4.93 | Aspirin for primary prevention of cardiovascular disease in patients with diabetes: A meta-analysis. ( Berlie, HD; Garwood, CL; Kokoska, LA; Wilhelm, SM, 2016) |
"Clinical trials investigating the role of aspirin in primary prevention have led to an adjustment in the indication for aspirin in metabolic syndrome patients at intermediate risk of a cardiovascular event." | 4.86 | A practical approach to the metabolic syndrome: review of current concepts and management. ( Blaha, MJ; Blumenthal, RS; Defilippis, AP; Tota-Maharaj, R, 2010) |
"The benefits of aspirin therapy in reducing the subsequent risk of myocardial infarction, stroke and death is well documented in individuals with cardiovascular disease including those with diabetes mellitus (DM)." | 4.85 | Aspirin therapy and primary prevention of cardiovascular disease in diabetes mellitus. ( Soran, H; Williams, S; Younis, N, 2009) |
" We used the search terms metabolic syndrome, abdominal obesity, waist circumference, insulin resistance, cardiovascular disease, prediabetes, diabetes, treatment, prevention, aspirin, hypertension, cholesterol, atherogenic dyslipidemia, lifestyle therapy, diet, and exercise." | 4.84 | A practical "ABCDE" approach to the metabolic syndrome. ( Bansal, S; Blaha, MJ; Blumenthal, RS; Defilippis, AP; Golden, SH; Rouf, R, 2008) |
"Aspirin is recommended as cardiovascular disease prevention in patients with diabetes mellitus." | 4.84 | [Low-dose aspirin in patients with diabete melitus: risks and benefits regarding macro and microvascular complications]. ( Camargo, EG; Gross, JL; Lavinsky, J; Silveiro, SP; Weinert, LS, 2007) |
" Increased leptin, dysregulation of adipocyte proteins, increased insulin resistance and C-reactive protein may be factors involved in the increased incidence of cardiovascular morbidity and mortality directly related to obesity." | 4.83 | Stroke prevention in diabetes and obesity. ( Govindarajan, G; Kurukulasuriya, LR; Sowers, J, 2006) |
"The study pooled individual data from 2580 participants with nonvalvular AF who were prescribed aspirin in a multicenter trial (Atrial Fibrillation, Aspirin, Anticoagulation I study [AFASAK-1], AFASAK-2, European Atrial Fibrillation Trial, Primary Prevention of Arterial Thromboembolism in patients with nonrheumatic Atrial Fibrillation in primary care study, and Stroke Prevention and Atrial Fibrillation [SPAF]-III high risk or SPAF-III low risk)." | 4.82 | Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin. ( Boode, BS; Gage, BF; Hart, RG; Koudstaal, PJ; Pearce, L; Petersen, P; van Walraven, C, 2004) |
" Aspirin is one of the most prescribed treatments in the prevention of cardiovascular diseases." | 4.82 | [Should we treat all diabetic patients with aspirin in primary prevention?]. ( De Moerloose, P; Philippe, J; Righetti, A, 2005) |
"The alterations in the metabolism of arachidonic acid to prostaglandin I2 (prostacyclin), a vasodilator antiaggregatory substance, and thromboxane A2, a vasoconstrictor proaggregatory substance, in diabetes mellitus are reviewed in this article." | 4.77 | Insulin and arachidonic acid metabolism in diabetes mellitus. ( Colwell, JA; Halushka, PV; Mayfield, R, 1985) |
"This study aimed to evaluate whether there is an association between the US Preventive Services Taskforce aspirin guideline hypertensive disorders of pregnancy and the rates of hypertensive disorders of pregnancy and preterm birth in individuals with pregestational diabetes mellitus." | 4.31 | Hypertensive disorders of pregnancy pre- and postaspirin guideline publication in individuals with pregestational diabetes mellitus. ( Allshouse, AA; Bruno, AM; Metz, TD; Theilen, LH, 2023) |
"To investigate the association between low-dose aspirin use for primary prevention and self-reported kidney stones prevalence in the 40-79 years old population." | 4.31 | Association of low-dose aspirin use for primary prevention with self-reported kidney stones prevalence: a cross-sectional study. ( Chen, Y; Huang, F; Li, Y; Yang, M, 2023) |
"Among Chinese minor stroke/transient ischemic attack population, the efficacy of clopidogrel-aspirin therapy was decreased in patients with higher ABCD-GENE score." | 4.12 | Application of Age, Body Mass Index, Chronic Kidney Disease, Diabetes, and Genotyping Score for Efficacy of Clopidogrel: Secondary Analysis of the CHANCE Trial. ( Chen, Z; Dai, L; Li, H; Meng, X; Pan, Y; Wang, Y; Xu, J; Yan, H, 2022) |
"Current guidelines recommend low-dose aspirin for preeclampsia prophylaxis in all women with pregestational (type one and type two) diabetes mellitus." | 4.12 | Associations between aspirin prophylaxis and fetal growth and preeclampsia in women with pregestational diabetes. ( Graham, DF; Shrestha Khatri, N; White, SW, 2022) |
"Patients with diabetes and no obstructive coronary artery disease (CAD) as assessed by coronary angiography (CAG) are frequently treated with aspirin and statins." | 4.12 | Statin but not aspirin treatment is associated with reduced cardiovascular risk in patients with diabetes without obstructive coronary artery disease: a cohort study from the Western Denmark Heart Registry. ( Bøtker, HE; Heide-Jørgensen, U; Maeng, M; Olesen, KKW; Sørensen, HT; Thim, T; Thomsen, RW, 2022) |
"Ticagrelor plus aspirin could reduce the risks of major adverse cardiac events in diabetic patients with stable coronary artery disease (SCD), and yet it also increases bleeding risk." | 4.02 | Cost-utility of ticagrelor plus aspirin in diabetic patients with stable coronary artery disease. ( Shi, L; Wu, B, 2021) |
"Acetylsalicylic acid (aspirin) is commonly used for primary and secondary prevention of cardiovascular diseases." | 4.02 | The use of aspirin for primary prevention of cardiovascular disease is associated with a lower likelihood of COVID-19 infection. ( Avramovich, E; Frenkel-Morgenstern, M; Golan-Cohen, A; Gorohovski, A; Green, I; Magen, E; Merzon, E; Vinker, S, 2021) |
"Aspirin is routinely prescribed in high-risk pregnancies to prevent pre-eclampsia; however, there is a paucity of data in women with pre-existing diabetes." | 4.02 | Aspirin and pre-eclampsia prevention in women with pre-existing diabetes: a retrospective study. ( Athayde, N; Cheung, NW; Inglis, E; Lah, S; Lee, V; Padmanabhan, S, 2021) |
"The present study concluded that long-term dual antiplatelet therapy including clopidogrel and aspirin could decrease the risks of all-cause death, myocardial infarction." | 4.02 | Treatment Outcomes of Clopidogrel in Patients With ACS and Diabetes Undergoing PCI-Analysis of Beijing Municipal Medical Insurance Database. ( Guo, L; Man, F; Pan, Q; Wang, W; Wang, X; Zhang, J; Zhang, L, 2021) |
"This study aimed to determine the effect of preoperative aspirin administration on early and long-term clinical outcomes in patients suffering from diabetes mellitus (DM) undergoing coronary artery bypass grafting (CABG)." | 3.96 | Impact of Preoperative Aspirin on Long-Term Outcomes in Diabetic Patients Following Coronary Artery Bypass Grafting: a Propensity Score Matched Study. ( Aboul-Hassan, SS; Cichon, R; Lipowski, A; Marczak, J; Moskal, L; Nawotka, M; Peksa, M; Sá, MPBO; Stanislawski, R; Stankowski, T, 2020) |
"Whether or not the use of metformin decreases the risk of gastric adenocarcinoma is unclear." | 3.91 | Metformin use and risk of gastric adenocarcinoma in a Swedish population-based cohort study. ( Lagergren, J; Santoni, G; Xie, SH; Zheng, J, 2019) |
"We examined whether the efficacy of low-dose acetylsalicylic acid (aspirin) for primary prevention of cardiovascular events is influenced by blood pressure (BP) using data from patients aged 60-85 years with hypertension, dyslipidemia, and/or diabetes, but without cardiovascular disease of the Japanese Primary Prevention Project." | 3.91 | Influence of blood pressure on the effects of low-dose asprin in elderly patients with multiple atherosclerotic risks. ( Ando, K; Ikeda, Y; Ishizuka, N; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Uemura, Y; Yamazaki, T; Yokoyama, K, 2019) |
" In diabetic patients treated with DAPT (ASA + clopidogrel or ticagrelor) platelet reactivity was assessed at 30-90 days post-discharge for an acute coronary syndrome or elective PCI." | 3.91 | Impact of aging on platelet reactivity in diabetic patients receiving dual antiplatelet therapy. ( Carriero, A; De Luca, G; Kedhi, E; Nardin, M; Pergolini, P; Rolla, R; Suryapranata, H; Tonon, F; Verdoia, M, 2019) |
"High plasma level of HbA1c is involved in enhanced platelet aggregability in acute atherothrombotic stroke patients, and prestroke administration of aspirin may be beneficial to clinical outcomes." | 3.91 | Collagen-Induced Platelet Aggregates, Diabetes, and Aspirin Therapy Predict Clinical Outcomes in Acute Ischemic Stroke. ( Hagii, J; Harima, K; Honda, S; Kitajima, M; Metoki, H; Mikami, K; Osanai, T; Tomisawa, T; Urushizaka, M; Yasujima, M, 2019) |
"Among diabetic patients receiving dual antiplatelet therapy for an acute coronary syndrome or elective percutaneous coronary intervention, severe vitamin D deficiency is associated with a higher ADP-mediated platelet reactivity and rate of HRPR, and especially for new ADP-antagonists over clopidogrel." | 3.91 | Vitamin D levels and platelet reactivity in diabetic patients receiving dual antiplatelet therapy. ( Carriero, A; De Luca, G; Kedhi, E; Marcolongo, M; Nardin, M; Negro, F; Pergolini, P; Rolla, R; Suryapranata, H; Verdoia, M, 2019) |
" Recommendations address diagnosis and treatment of cardiovascular risk factors (hypertension and dyslipidemia), aspirin use, screening for and treatment of coronary heart disease, and lifestyle interventions." | 3.88 | Cardiovascular Disease and Risk Management: Review of the American Diabetes Association Standards of Medical Care in Diabetes 2018. ( Chamberlain, JJ; Johnson, EL; Leal, S; Peterson, L; Rhinehart, AS; Shubrook, JH, 2018) |
"Our findings suggest that a cumulative aspirin dosage of more than 88,900 mg daily was associated with a reduced risk of breast cancer in women with diabetes." | 3.85 | Low-Dose Aspirin Reduces Breast Cancer Risk in Women with Diabetes: A Nationwide Retrospective Cohort Study in Taiwan. ( Chiou, JY; Huang, CN; Kornelius, E; Lai, YR; Lo, SC; Peng, CH; Yang, YS, 2017) |
"Seventy patients with stable coronary artery disease, supplemented with aspirin, participated in this pilot study." | 3.85 | MMP-2, MMP-9, and TIMP-4 and Response to Aspirin in Diabetic and Nondiabetic Patients with Stable Coronary Artery Disease: A Pilot Study. ( Bil-Lula, I; Gąsior, M; Kaczmarski, J; Kuliczkowski, W; Mysiak, A; Negrusz-Kawecka, M; Radomski, M; Urbaniak, J, 2017) |
" In a cross-sectional study of 787 patients with newly diagnosed clinical stage IB or II melanoma, we estimated odds ratios for the association of proinflammatory factors (high body mass index, diabetes, cardiovascular disease, hypertension, and smoking) or the use of anti-inflammatory medications (statins, aspirin, corticosteroids, and nonsteroidal anti-inflammatory drugs), with ulcerated primary melanoma using regression models and subgroup analyses to control for melanoma thickness and mitotic rate." | 3.85 | Associations of Statins and Diabetes with Diagnosis of Ulcerated Cutaneous Melanoma. ( Green, AC; Hughes, MCB; Khosrotehrani, K; Malt, M; Smith, D; Smithers, BM; van der Pols, JC; von Schuckmann, LA, 2017) |
"The combined use of aspirin and oral anticoagulant therapy in patients with atrial fibrillation (AF) and stable coronary artery disease (CAD) has been questioned due to an increased risk of major bleeding with little to no benefit in preventing ischemic events." | 3.85 | Combined aspirin and anticoagulant therapy in patients with atrial fibrillation. ( Eckman, MH; So, CH, 2017) |
" Diabetes mellitus and current smoker status were independent factors related to reactivity to clopidogrel." | 3.83 | Influence of Diabetes Mellitus and Cigarette Smoking on Variability of the Clopidogrel-Induced Antiplatelet Effect and Efficacy of Active Management of the Target P2Y12 Reaction Unit Range in Patients Undergoing Neurointerventional Procedures. ( Hironaka, Y; Kichikawa, K; Motoyama, Y; Nakagawa, I; Nakase, H; Park, HS; Takayama, K; Wada, T; Yokoyama, S, 2016) |
" In patients treated with ASA (100-160 mg) and clopidogrel (75 mg daily) or ticagrelor (90 mg twice a day) platelet reactivity and the reticulated platelets fraction (immature platelets fraction, IPF) were assessed at 30-90 days post-discharge for an acute coronary syndrome or elective PCI." | 3.83 | Impact of diabetes on immature platelets fraction and its relationship with platelet reactivity in patients receiving dual antiplatelet therapy. ( Barbieri, L; Bellomo, G; De Luca, G; Marino, P; Nardin, M; Pergolini, P; Rolla, R; Schaffer, A; Suryapranata, H; Verdoia, M, 2016) |
"Dual-antiplatelet therapy with aspirin and clopidogrel after percutaneous coronary intervention reduces the risk for coronary thrombotic events (CTEs) at the expense of increasing risk for major bleeding (MB)." | 3.83 | Coronary Thrombosis and Major Bleeding After PCI With Drug-Eluting Stents: Risk Scores From PARIS. ( Ariti, C; Baber, U; Chieffo, A; Cohen, DJ; Colombo, A; Dangas, G; Gibson, CM; Giustino, G; Henry, TD; Kini, AS; Kirtane, AJ; Krucoff, MW; Litherland, C; Mehran, R; Moliterno, DJ; Pocock, S; Sartori, S; Steg, PG; Stone, GW; Weisz, G; Witzenbichler, B, 2016) |
"To evaluate the efficacy and safety of aspirin usage for coronary heart disease (CHD) primary prevention in patients with dyslipidemia." | 3.83 | Effects of low-dose aspirin in subjects with dyslipidemia. ( Chen, J; Lou, G; Xia, Y, 2016) |
"To evaluate whether aspirin can reduce the risk of colorectal cancer in people with diabetes." | 3.81 | Can aspirin reduce the risk of colorectal cancer in people with diabetes? A population-based cohort study. ( Lai, MS; Lin, CC; Shau, WY, 2015) |
"Low-dose aspirin has been hypothesized as being a potential host modulatory agent for periodontitis treatment." | 3.81 | Association between low-dose aspirin and periodontal disease: results from the continuous national health and nutrition examination survey (NHANES) 2011-2012. ( Demmer, RT; Ioannou, AL; Kotsakis, GA; Michalowicz, BS; Thai, A, 2015) |
"The US Preventive Services Task Force recommends aspirin use for men aged 45 to 79, when the potential benefit of preventing myocardial infarctions outweighs the potential harm of gastrointestinal hemorrhage." | 3.81 | Aspirin Use for the Primary Prevention of Myocardial Infarction Among Men in North Carolina, 2013. ( Fleming, E; Perry, GS; Tchwenko, S, 2015) |
"Use of warfarin, low GCS score, opening to ventricle, older age, accompanying diabetes, and/or hypertension were worse prognostic factors." | 3.80 | Intracranial hemorrhages related with warfarin use and comparison of warfarin and acetylsalicylic acid. ( Beckmann, Y; Ciftçi, Y; Seçil, Y; Tokuçoğlu, F, 2014) |
" In addition, patients in the 6 am to 2 pm subgroup were more likely older, white race, and male, with higher rates of home aspirin use and lower rates of obesity." | 3.79 | Relation between time of symptom onset of ST-segment elevation myocardial infarction and patient baseline characteristics: from the National Cardiovascular Data Registry. ( Antman, EM; Cannon, CP; Foody, JM; Giugliano, RP; Li, S; Mogabgab, O; Sabatine, MS; Wang, TY; Wiviott, SD, 2013) |
"Long-term administration of low-dose aspirin (LDA) is associated with a greater risk of adverse events, including gastroduodenal ulcers." | 3.79 | Low-dose aspirin-associated upper gastric and duodenal ulcers in Japanese patients with no previous history of peptic ulcers. ( Funaki, Y; Iida, A; Ito, Y; Kasugai, K; Kawamura, N; Mizuno, M; Ogasawara, N; Sasaki, M, 2013) |
"Diabetes mellitus (DM) is associated with increased platelet activation and reduced platelet inhibition by clopidogrel." | 3.79 | Inhibition of platelet aggregation by prostaglandin E1 (PGE1) in diabetic patients during therapy with clopidogrel and aspirin. ( Desta, Z; Flockhart, DA; Jin, Y; Kovacs, R; Kreutz, RP; Kreutz, Y; Miao, J; Nystrom, P, 2013) |
"The widespread use of aspirin-driven vascular prevention strategies does not impede the occurrence of first and recurrent ischemic strokes in numerous subjects." | 3.78 | Ischemic stroke in patients receiving aspirin. ( Ameriso, S; Ameriso, SF; Povedano, GP; Pujol Lereis, VA, 2012) |
"The proper use of statins and aspirin decrease the risk of coronary heart disease (CHD) among patients with diabetes (DM) and hyperlipidemia." | 3.78 | Utilization of statins and aspirin among patients with diabetes and hyperlipidemia: Taiwan, 1998-2006. ( Chen, YJ; Hwu, CM; Li, CY; Lin, YC; Peng, WC; Yang, CC, 2012) |
"Exploration of atherogenic diet-induced diabetes mellitus and the evaluation of antidiabetic potential of aspirin were carried out in this study." | 3.77 | The effect of aspirin on atherogenic diet-induced diabetes mellitus. ( Kumar, A; Parmar, HS; Sethi, A, 2011) |
"We sought to assess the impact of renal function on platelet reactivity in patients with diabetes mellitus (DM) and coronary artery disease on aspirin and clopidogrel therapy." | 3.76 | Impact of chronic kidney disease on platelet function profiles in diabetes mellitus patients with coronary artery disease taking dual antiplatelet therapy. ( Alfonso, F; Angiolillo, DJ; Bass, TA; Bernardo, E; Capodanno, D; Fernandez-Ortiz, A; Ferreiro, JL; Jimenez-Quevedo, P; Macaya, C; Sabaté, M; Ueno, M; Vivas, D, 2010) |
"Treatment with aspirin is underused for PP in patients with diabetes mellitus in Primary Care." | 3.74 | Use of aspirin for primary and secondary prevention of cardiovascular disease in diabetic patients in an ambulatory care setting in Spain. ( Fernández-de-Bobadilla, J; Frías-Garrido, X; Navarro-Artieda, R; Rejas-Gutiérrez, J; Ruiz-Riera, R; Sicras-Mainar, A, 2007) |
"There have been no randomized trials of cardioprotective therapy after acute myocardial infarction in patients with chronic kidney disease who should be largely eligible for aspirin (acetylsalicylic acid; ASA) and beta-blockers (BB) as a base of therapy." | 3.71 | Benefits of aspirin and beta-blockade after myocardial infarction in patients with chronic kidney disease. ( Borzak, S; Garg, M; Hudson, MP; Manley, HJ; McCullough, PA; Sandberg, KR, 2002) |
"Elderly men are more likely than elderly women to receive aspirin and ticlopidine and equally like to receive warfarin after a stroke." | 3.70 | Sex differences and similarities in the management and outcome of stroke patients. ( Austin, PC; Holroyd-Leduc, JM; Kapral, MK; Tu, JV, 2000) |
"(1) Aspirin reduces the risk of myocardial infarction in men over 40 with no history of cardiovascular disease, and in hypertensive patients of both sexes over that age." | 3.70 | Antiplatelet drugs in cardiovascular prevention: coronary events and stroke: primary prevention. ( , 2000) |
"The results of two large independent studies involving a combined total of 776 patients treated in hospital with a discharge diagnosis of acute myocardial infarction and 13,898 patients with other discharge diagnoses showed a negative association between regular aspirin intake and non-fatal myocardial infarction." | 3.65 | Regular aspirin intake and acute myocardial infarction. ( , 1974) |
"Proteinuria was independently associated with the incidence of primary cardiovascular events in diabetic patients." | 2.94 | Proteinuria is independently associated with the incidence of primary cardiovascular events in diabetic patients. ( Jinnouchi, H; Masuda, I; Matsumoto, C; Morimoto, T; Nakayama, M; Ogawa, H; Okada, S; Saito, Y; Soejima, H; Waki, M, 2020) |
"Aspirin treatment may have reduced CVEs within a high CVE risk elderly population subgroup." | 2.90 | Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in Elderly Japanese Patients with Atherosclerotic Risk Factors: Subanalysis of a Randomized Clinical Trial (JPPP-70). ( Ando, K; Goto, Y; Ikeda, Y; Ishizuka, N; Murata, M; Oikawa, S; Shimada, K; Sugawara, M; Teramoto, T; Uchiyama, S; Uemura, Y; Yamazaki, T; Yokoyama, K, 2019) |
"The protective effect of statin against gastric cancer was also significant in patients with diabetes mellitus." | 2.82 | Aspirin, metformin, and statin use on the risk of gastric cancer: A nationwide population-based cohort study in Korea with systematic review and meta-analysis. ( Bang, CS; Kim, HH; Kim, J; Kim, JY; Kim, TJ; Lee, KJ; Park, CH; Seo, SI; Shin, WG; You, SC, 2022) |
" Previous pharmacokinetic and pharmacodynamic studies have suggested that the aspirin formulation (enteric-coated) and dosing schedule (once daily) studied in randomized trials for primary prevention of CV events defining contemporary clinical practice may not leverage the full potential of the drug, particularly in patients with diabetes." | 2.82 | Aspirin for Primary Cardiovascular Prevention in Patients with Diabetes: Uncertainties and Opportunities. ( Bloom, S; Del Bianco-Rondeau, M; Lordkipanidzé, M; Marquis-Gravel, G; Rabasa-Lhoret, R; Robert-Halabi, M; Tardif, JC, 2022) |
" However, the effects of EV-077 on pharmacodynamic (PD) profiles in patients with DM and coronary artery disease (CAD) while on antiplatelet therapy is poorly explored and represented the aim of this in vitro pilot investigation." | 2.79 | Pharmacodynamic effects of EV-077 in patients with diabetes mellitus and coronary artery disease on aspirin or clopidogrel monotherapy: results of an in vitro pilot investigation. ( Angiolillo, DJ; Bender, N; Darlington, A; Desai, B; Franchi, F; Muñiz-Lozano, A; Patel, R; Rollini, F; Sakariassen, KS; Tello-Montoliu, A; Wilson, RE, 2014) |
"Cilostazol is a platelet inhibitor which when added to aspirin and clopidogrel has shown to reduce the risk of recurrent ischaemic events without an increase in bleeding." | 2.76 | Impact of adjunctive cilostazol therapy on platelet function profiles in patients with and without diabetes mellitus on aspirin and clopidogrel therapy. ( Angiolillo, DJ; Bass, TA; Box, LC; Capodanno, D; Capranzano, P; Charlton, RK; Darlington, A; Desai, B; Dharmashankar, K; Ferreiro, JL; Guzman, LA; Sumner, S; Ueno, M; Zenni, M, 2011) |
"Eptifibatide was not associated with an increase in intracranial hemorrhage, and no significant effect on nonhemorrhagic stroke was observed." | 2.69 | Stroke in patients with acute coronary syndromes: incidence and outcomes in the platelet glycoprotein IIb/IIIa in unstable angina. Receptor suppression using integrilin therapy (PURSUIT) trial. The PURSUIT Investigators. ( Alberts, MJ; Berdan, LG; Califf, RM; Deckers, J; Graffagnino, C; Granger, CB; Harrington, RA; Laskowitz, DT; Lincoff, AM; MacAulay, CM; Mahaffey, KW; Miller, JM; Simoons, ML; Sloan, MA; Topol, EJ, 1999) |
"Observational data from the Early Treatment Diabetic Retinopathy Study." | 2.68 | Association of elevated serum lipid levels with retinal hard exudate in diabetic retinopathy. Early Treatment Diabetic Retinopathy Study (ETDRS) Report 22. ( Chantry, K; Chew, EY; Ferris, FL; Hoogwerf, BJ; Klein, ML; Miller, D; Murphy, RP; Remaley, NA, 1996) |
" Further dosage adjustments are made in accordance with a set protocol." | 2.67 | The Hypertension Optimal Treatment (HOT) Study--patient characteristics: randomization, risk profiles, and early blood pressure results. ( Hansson, L; Zanchetti, A, 1994) |
"Aspirin has potential benefits in cardiovascular primary prevention in diabetes." | 2.61 | Aspirin has potential benefits for primary prevention of cardiovascular outcomes in diabetes: updated literature-based and individual participant data meta-analyses of randomized controlled trials. ( Buring, JE; Gaziano, JM; Khunti, K; Kunutsor, SK; Roncaglioni, MC; Seidu, S; Sesso, HD, 2019) |
"Aspirin was associated with reductions in major cardiovascular events (risk ratio, 0." | 2.50 | Aspirin for primary prevention of cardiovascular events: meta-analysis of randomized controlled trials and subgroup analysis by sex and diabetes status. ( Bao, W; Chen, S; Hu, FB; Liu, L; Rong, Y; Shan, Z; Xie, M; Yang, W; Yu, X; Zhang, Y, 2014) |
"Aspirin use was associated with a significantly lower risk of mortality (RR: 0." | 2.47 | Effect of aspirin dose on mortality and cardiovascular events in people with diabetes: a meta-analysis. ( Chambers, T; Gamble, JM; Mereu, L; Simpson, SH, 2011) |
"Diabetes mellitus is commonly associated with both microvascular and macrovascular complications (coronary artery disease, cerebrovascular events, severe peripheral vascular disease, nephropathy and retinopathy)." | 2.45 | Diabetes, vascular complications and antiplatelet therapy: open problems. ( Cerbone, AM; Coppola, A; Di Minno, G; Macarone-Palmieri, N; Rivellese, AA; Saldalamacchia, G, 2009) |
"Diabetes mellitus is a well-recognized risk-factor for coronary artery disease." | 2.43 | [Coronary heart disease in patients with diabetes mellitus]. ( Nakayama, M; Ogawa, H, 2006) |
"Management of hypertension in diabetic nephropathy is challenging and generally requires a minimum of three different and complementary antihypertensive agents to achieve the recently recommended blood pressure (BP) goal of <130/80 mm Hg in order to reduce cardiovascular (CV) risk and preserve kidney function." | 2.42 | Diabetes and chronic kidney disease: tragedy and challenge. ( Bakris, GL; Chua, DY, 2004) |
"Diabetes mellitus is another CHD risk factor which is stronger in women than in men, and CHD death rates are 3-7 times greater among diabetic than nondiabetic women." | 2.40 | Risk factors for coronary heart disease in women. ( Hennekens, CH, 1998) |
"Aspirin treatment again has similar benefits to those in non-diabetic subjects, and should be administered at presentation." | 2.40 | Managing the diabetic patient with acute myocardial infarction. ( Yudkin, JS, 1998) |
"001) in a dose-response fashion, and these associations were prominent among participants with a metformin cumulative defined daily dose of 547." | 1.62 | The Associations of Aspirin, Statins, and Metformin With Lung Cancer Risk and Related Mortality: A Time-Dependent Analysis of Population-Based Nationally Representative Data. ( Cho, JH; Cho, M; Jeong, SM; Kang, J; Kim, J; Shin, DW, 2021) |
"Objectives A "potential drug-drug interaction" (pDDI) is the possibility one drug has to alter the effects of another when both are administered simultaneously." | 1.56 | Potential drug-drug interactions in ICU patients: a retrospective study. ( Ali, I; Bazzar, A; Hussein, N; Sahhar, E, 2020) |
"Aspirin is an effective, low cost option to reduce cardiovascular events." | 1.51 | Aspirin Use for Cardiovascular Disease Prevention in an African American Population: Prevalence and Associations with Health Behavior Beliefs. ( Duval, S; Eder, M; Jones, C; Luepker, RV; Misialek, JR; Oldenburg, NC; Van't Hof, JR, 2019) |
"The aims of this study are to find the prevalence of potential drug-drug interactions (DDIs) in patients with Hemodialysis and identify factors associated with these interactions if present." | 1.43 | Evaluation of potential drug- drug interactions among Palestinian hemodialysis patients. ( Abu-Ghazaleh, D; Al-Ramahi, R; Bsharat, A; Raddad, AR; Rashed, AO; Shehab, O; Yasin, E, 2016) |
"Diabetes mellitus has been associated with a substantially increased risk of both first and recurrent atherothrombotic events, which makes aspirin therapy of potential value in these subjects." | 1.43 | Aspirin for Primary Cardiovascular Risk Prevention and Beyond in Diabetes Mellitus. ( Angiolillo, DJ; Capodanno, D, 2016) |
"Diabetes mellitus is an independent predictor of adverse clinical events after drug-eluting stent implantation." | 1.39 | Clinical efficacy and safety of biodegradable polymer-based sirolimus-eluting stents in patients with diabetes mellitus insight from the 4-year results of the create study. ( Chen, X; Han, Y; Jiang, T; Jing, Q; Li, Y; Liu, H; Ma, Y; Wang, G; Wang, S; Wang, X; Yan, G; Yang, L; Zhang, L; Zhu, G, 2013) |
"Medical records of 659 patients treated for myocardial infarction at the 1st Department of Internal Medicine-Cardiology of Borsod-Abaúj-Zemplén County Hospital and University Hospital were analyzed." | 1.39 | Pharmaceutical care for patients with acute myocardial infarction in Hungary. ( Argay, M; Dormaeva, I; Hankó, B; Koós, I; Meskó, A; Takács, I; Zelkó, R, 2013) |
"Diabetes mellitus is associated with platelet hyperactivity, which leads to increased morbidity and mortality from cardiovascular disease." | 1.37 | Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane. ( Capone, M; Di Febbo, C; Evangelista, V; Fava, C; Gleim, S; Hwa, J; Levantesi, G; Martin, K; Minuz, P; Patrignani, P; Porreca, E; Rade, J; Stitham, J; Tacconelli, S; Tang, WH; Wen, L, 2011) |
"The TRUE registry demonstrated that SES in the treatment of bare-metal stent ISR is efficacious (5% of target lesion revascularization [TLR]) and safe (stent thrombosis <1%) at 9 months." | 1.36 | Long-term effectiveness and safety of sirolimus stent implantation for coronary in-stent restenosis results of the TRUE (Tuscany Registry of sirolimus for unselected in-stent restenosis) registry at 4 years. ( Angioli, P; Bolognese, L; Carrera, A; Ducci, K; Falsini, G; Fineschi, M; Gori, T; Grotti, S; Liistro, F; Pierli, C, 2010) |
"Aspirin use was reported in 50% of patients: 68." | 1.36 | Aspirin use in elderly women receiving medication therapy management services. ( Cooke, CE; Lee, HY; Tong, YP; Xing, S, 2010) |
"Age and left bundle branch block were strong negative predictors for early reperfusion therapy in patients with prior antithrombotic treatment." | 1.35 | Impact of chronic antithrombotic therapy on hospital course of patients with acute myocardial infarction. ( Bauer, T; Bestehorn, K; Gitt, A; Jünger, C; Koeth, O; Senges, J; Towae, F; Zahn, R; Zeymer, U, 2009) |
" We assessed the cumulative incidence of major adverse cardiac events (death, acute myocardial infarction, and target-vessel revascularization) and angiographic stent thrombosis during 2-year follow-up." | 1.34 | Long-term safety and efficacy of drug-eluting stents: two-year results of the REAL (REgistro AngiopLastiche dell'Emilia Romagna) multicenter registry. ( Aurier, E; Benassi, A; Cremonesi, A; Grilli, R; Guastaroba, P; Magnavacchi, P; Manari, A; Maresta, A; Marzocchi, A; Percoco, G; Piovaccari, G; Saia, F; Varani, E, 2007) |
"Aspirin use was significantly lower among the study participants (23%) compared to the reported national prevalence of aspirin intake (64%)." | 1.34 | Health issues in the Arab American community. The use of glucose-lowering agents and aspirin among Arab Americans with diabetes. ( Berlie, HD; Hammad, A; Jaber, LA, 2007) |
"The progress of leukoaraiosis is greatly inhibited by long-term correction of platelet hyper-aggregability." | 1.33 | Progress of leukoaraiosis is inhibited by correction of platelet hyper-aggregability. ( Fujita, S; Fukushima, K; Kawaguchi, T; Uehara, T, 2005) |
"Aspirin non-response was defined as: 1) slope steeper than 12%/min in AA-aggregations, and 2) by closure time shorter than 170 s in PFA-100." | 1.33 | Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients. ( Backman, JT; Kankuri, E; Karhunen, PJ; Lassila, R; Lepäntalo, A; Mikkelsson, J; Reséndiz, JC; Viiri, L, 2006) |
"Diabetes mellitus is a major public health problem in the United States." | 1.33 | Increased cardiovascular risk associated with diabetes in Dallas County. ( Das, SR; de Lemos, JA; Dobbins, RL; McGuire, DK; Stanek, HG; Vaeth, PA, 2006) |
"People with diabetes mellitus have higher risk of cardiovascular morbidity and mortality from thrombo-vascular complications than non-diabetics and it is recommended that they should use acetylsalicylic acid (ASA) as anitiplatelet agent regularly." | 1.33 | Acetylsalicylic acid (ASA) use among Polish adults with diabetes mellitus. ( Drzewoski, J; Liniarski, M; Olszewski, A; Sawer-Szewczyk, J; Stepień, A, 2005) |
"Diabetes Mellitus is a chronic disease frequently associated to ischemic heart disease and both disease require continuing medical care, aggressive treatment of other risk factors, educational programs for self management of disease to prevent acute complication." | 1.32 | [Recommendations for cardiovascular rehabilitation in diabetes mellitus]. ( Biorci, ML; Camerini, A; Chieffo, C; Comaschi, M; Faglia, E; Fattirolli, F; Gattone, M; Giorda, C; Griffo, R; Mannucci, E, 2003) |
" A dose-response relationship was evident between incident opacities and increased levels of glycosylated hemoglobin at baseline, with the highest risk of cortical (RR = 3." | 1.32 | Risk factors for incident cortical and posterior subcapsular lens opacities in the Barbados Eye Studies. ( Hennis, A; Leske, MC; Nemesure, B; Wu, SY, 2004) |
"Unstable angina was defined as transient S-T segment changes without significant increases in CK and CK-MB." | 1.31 | Prior aspirin use in unstable angina patients with modified plasma inflammatory markers and endothelial nitric oxide synthase in neutrophils. ( de Andres, R; Farré, J; García-Méndez, A; Gómez, J; López-Farré, A; Mateos-Cáreres, PJ; Rico, L; Romero, J; Sánchez de Miguel, L, 2002) |
"Aspirin was used regularly by 37% of those with CVD and by 13% of those with risk factors only Adjusted odds of regular aspirin use were significantly greater for individuals with CVD than for those with one CVD risk factor (odds ratio [OR] = 4." | 1.31 | Aspirin use among adults with diabetes: estimates from the Third National Health and Nutrition Examination Survey. ( Fagot-Campagna, A; Narayan, KM; Rolka, DB, 2001) |
"The value of treatment of hyperlipidemia in reducing the incidence of a first stroke remains to be demonstrated." | 1.28 | Ischemic stroke. How to keep the first one from happening. ( Bundlie, SR, 1991) |
"Patients with transient ischemic attacks (TIA) were previously shown to have high plasma values of thiobarbituric acid-reactive substances (TBA-RS)." | 1.28 | Blood lipid peroxides in TIA: relation to platelet function and metabolic profile. ( Alessandri, C; Balsano, F; Caliendo, C; Censi, C; Germani, M; Ghiselli, A; Servi, M; Violi, F, 1989) |
" One-step extraction of UTXB2 with an octadecylsilyl-silica column was sufficient as pretreatment for TXB2 radioimmunoassay because recovery of UTXB2 was good, the eluate was parallel with the dose-response curve, and the value coincided with that obtained by the conventional method." | 1.27 | Increased thromboxane B2 excretion in diabetes mellitus. ( Inaba, M; Ishii, J; Katayama, S; Kawazu, S; Maruno, Y; Omoto, A, 1987) |
"Human diabetes mellitus is characterized by impaired insulin response to intravenous glucose." | 1.26 | Impaired insulin secretion in human diabetes mellitus. II. A possible role for prostaglandins. ( Coppola, L; Giugliano, D; Misso, L; Sgamboto, S; Torella, R, 1981) |
" Nine of 14 diabetics received a dosage of 1." | 1.26 | Effect of acetylsalicylic acid on blood glucose and glucose regulatory hormones in mild diabetes. ( Ikeda, M; Imura, H; Ishida, H; Nakahara, H; Nishi, S; Seino, Y; Takemura, J; Usami, M, 1982) |
"Diclofenac (Voltarol) has no effect on carbohydrate metabolism, insulin levels or tolbutamide metabolism, nor does it enhance the effect of tolbutamide, biguanide or glibenclamide." | 1.26 | Diclofenac sodium (Voltarol): drug interactions and special studies. ( Fowler, PD, 1979) |
" In the uncommon occurrence of asthma and diabetes in the same patient, insulin dosage should be considered as a factor in all such asthmatics who do not respond well to conventional therapy." | 1.26 | Diabetes mellitus and insulin in an aspirin sensitive asthmatic. ( Caplin, I, 1976) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 89 (19.73) | 18.7374 |
1990's | 31 (6.87) | 18.2507 |
2000's | 110 (24.39) | 29.6817 |
2010's | 144 (31.93) | 24.3611 |
2020's | 77 (17.07) | 2.80 |
Authors | Studies |
---|---|
Zhang, HB | 1 |
Zhang, YA | 1 |
Wu, GZ | 1 |
Zhou, JP | 1 |
Huang, WL | 1 |
Hu, XW | 1 |
Kow, CS | 1 |
Ramachandram, DS | 1 |
Hasan, SS | 1 |
Altınay, L | 1 |
Çetin, E | 1 |
Tantry, US | 1 |
Gurbel, PA | 1 |
Dai, L | 1 |
Xu, J | 1 |
Yan, H | 1 |
Chen, Z | 1 |
Pan, Y | 1 |
Meng, X | 1 |
Li, H | 2 |
Wang, Y | 1 |
Shrestha Khatri, N | 1 |
White, SW | 1 |
Graham, DF | 1 |
Zen, M | 1 |
Haider, R | 1 |
Simmons, D | 1 |
Peek, M | 1 |
Nolan, CJ | 1 |
Padmanabhan, S | 2 |
Jesudason, S | 1 |
Alahakoon, TI | 1 |
Cheung, NW | 2 |
Lee, VW | 1 |
Harper, C | 2 |
Mafham, M | 7 |
Herrington, W | 2 |
Staplin, N | 2 |
Stevens, W | 6 |
Wallendszus, K | 5 |
Haynes, R | 7 |
Landray, MJ | 2 |
Parish, S | 6 |
Bowman, L | 8 |
Armitage, J | 8 |
Seo, SI | 1 |
Park, CH | 1 |
Kim, TJ | 1 |
Bang, CS | 1 |
Kim, JY | 1 |
Lee, KJ | 1 |
Kim, J | 2 |
Kim, HH | 1 |
You, SC | 1 |
Shin, WG | 1 |
Masson, W | 1 |
Barbagelata, L | 1 |
Lavalle-Cobo, A | 1 |
Lobo, M | 1 |
Masson, G | 1 |
Nogueira, JP | 1 |
Vergès, B | 1 |
Del Bianco-Rondeau, M | 1 |
Robert-Halabi, M | 1 |
Bloom, S | 1 |
Rabasa-Lhoret, R | 1 |
Tardif, JC | 1 |
Lordkipanidzé, M | 1 |
Marquis-Gravel, G | 1 |
Cavallari, I | 3 |
Patti, G | 1 |
Maddaloni, E | 2 |
Veneziano, F | 2 |
Mangiacapra, F | 2 |
Ricottini, E | 2 |
Buzzetti, R | 1 |
Ussia, GP | 2 |
Grigioni, F | 2 |
Dehghani, P | 1 |
Cao, D | 1 |
Baber, U | 5 |
Nicolas, J | 1 |
Sartori, S | 4 |
Pivato, CA | 1 |
Zhang, Z | 1 |
Dangas, G | 4 |
Angiolillo, DJ | 12 |
Briguori, C | 2 |
Cohen, DJ | 6 |
Collier, T | 2 |
Dudek, D | 2 |
Gibson, M | 2 |
Gil, R | 1 |
Huber, K | 2 |
Kaul, U | 3 |
Kornowski, R | 2 |
Krucoff, MW | 3 |
Kunadian, V | 2 |
Mehta, S | 1 |
Moliterno, DJ | 3 |
Ohman, EM | 1 |
Escaned, J | 4 |
Sardella, G | 2 |
Sharma, SK | 1 |
Shlofmitz, R | 1 |
Weisz, G | 4 |
Witzenbichler, B | 4 |
Pocock, S | 4 |
Mehran, R | 5 |
Offer, A | 1 |
Barton, J | 4 |
Buck, G | 5 |
Collins, R | 5 |
Kristensen, SD | 2 |
Olesen, KKW | 3 |
Maeng, M | 4 |
Seng Bong Ing, N | 1 |
Amoud, R | 1 |
Gamble, JM | 2 |
Alsabbagh, MW | 1 |
Wang, M | 1 |
Yu, H | 1 |
Li, Z | 1 |
Gong, D | 1 |
Liu, X | 2 |
Mihaljevic, MZ | 1 |
Petricevic, M | 1 |
Konosic, S | 1 |
Svetina, L | 1 |
Urlic, M | 1 |
Starcevic, Z | 1 |
Krzelj, K | 1 |
Milosevic, M | 1 |
Kalamar, V | 1 |
Gasparovic, H | 1 |
Biocina, B | 1 |
Dimitriadis, K | 1 |
Lazarou, E | 1 |
Tsioufis, P | 1 |
Soulaidopoulos, S | 1 |
Tsioufis, K | 1 |
Tasdemiroglu, Y | 1 |
Gourdie, RG | 1 |
He, JQ | 1 |
Nobile, E | 1 |
De Filippis, A | 1 |
Galli, M | 1 |
Rollini, F | 2 |
Been, L | 1 |
Zenni, MM | 1 |
Franchi, F | 2 |
Park, IB | 3 |
Seo, HJ | 3 |
Dai, Y | 1 |
Xu, R | 1 |
Wu, G | 1 |
Yin, Z | 1 |
Zhang, H | 1 |
Chen, W | 1 |
Yang, YS | 2 |
Kornelius, E | 2 |
Lo, SC | 2 |
Wang, YH | 1 |
Huang, CN | 2 |
Caldeira, D | 2 |
Alves, M | 2 |
Ferreira, JJ | 2 |
Pinto, FJ | 2 |
Bruno, AM | 1 |
Allshouse, AA | 1 |
Metz, TD | 1 |
Theilen, LH | 1 |
Liu, S | 2 |
Eckstein, J | 1 |
Lam, A | 1 |
Cheema, AN | 1 |
Arambam, P | 1 |
Sinha, SK | 1 |
Abhaichand, R | 1 |
Parida, AK | 1 |
Banker, D | 1 |
Mody, R | 1 |
Khan, A | 1 |
Sharma, R | 2 |
Moorthy, N | 1 |
Chandra, S | 1 |
Koduganti, SC | 1 |
Garg, R | 1 |
Sarma, PR | 1 |
Agrawal, DK | 1 |
Reddy, KMK | 1 |
Bangalore, S | 2 |
Aung, T | 5 |
Clark, S | 1 |
Hill, MR | 1 |
Kristensen, AMD | 1 |
Pareek, M | 1 |
Kragholm, KH | 1 |
Torp-Pedersen, C | 1 |
McEvoy, JW | 1 |
Prescott, EB | 1 |
Rhee, TM | 1 |
Bae, JW | 1 |
Park, KW | 1 |
Rha, SW | 1 |
Kang, J | 2 |
Lee, H | 1 |
Yang, HM | 1 |
Kwak, SH | 1 |
Chae, IH | 2 |
Shin, WY | 1 |
Kim, DK | 1 |
Oh, JH | 1 |
Jeong, MH | 1 |
Kim, YH | 2 |
Lee, NH | 2 |
Hur, SH | 1 |
Yoon, J | 1 |
Han, JK | 1 |
Shin, ES | 1 |
Koo, BK | 1 |
Kim, HS | 3 |
Pugliese, NR | 1 |
Taddei, S | 1 |
Zhou, Z | 1 |
Curtis, AJ | 1 |
Owen, A | 1 |
Wolfe, R | 1 |
Murray, AM | 1 |
Tonkin, AM | 1 |
Ernst, ME | 1 |
Orchard, SG | 1 |
Zhu, C | 1 |
Carr, PR | 1 |
Reid, CM | 1 |
Espinoza, SE | 1 |
Shah, RC | 1 |
Woods, RL | 1 |
Ryan, J | 1 |
McNeil, JJ | 1 |
Nelson, MR | 1 |
Zoungas, S | 1 |
Verma, SK | 1 |
Kalra, S | 1 |
Chunawala, ZS | 1 |
Caughey, MC | 1 |
Bhatt, DL | 10 |
Hendrickson, M | 1 |
Arora, S | 1 |
Erwin, JP | 1 |
Levisay, JP | 1 |
Rosenberg, JR | 1 |
Ricciardi, MJ | 1 |
Blankstein, R | 1 |
Matsushita, K | 1 |
Smith, S | 1 |
Qamar, A | 1 |
Yang, M | 1 |
Li, Y | 3 |
Chen, Y | 1 |
Huang, F | 1 |
Schrör, K | 2 |
Storey, RF | 1 |
Verheugt, FWA | 1 |
Roshandel, G | 1 |
Khoshnia, M | 1 |
Poustchi, H | 1 |
Hemming, K | 1 |
Kamangar, F | 1 |
Gharavi, A | 1 |
Ostovaneh, MR | 1 |
Nateghi, A | 1 |
Majed, M | 1 |
Navabakhsh, B | 1 |
Merat, S | 1 |
Pourshams, A | 1 |
Nalini, M | 1 |
Malekzadeh, F | 1 |
Sadeghi, M | 1 |
Mohammadifard, N | 1 |
Sarrafzadegan, N | 1 |
Naemi-Tabiei, M | 1 |
Fazel, A | 1 |
Brennan, P | 1 |
Etemadi, A | 1 |
Boffetta, P | 1 |
Thomas, N | 1 |
Marshall, T | 1 |
Cheng, KK | 1 |
Malekzadeh, R | 1 |
Rosenberg, K | 1 |
Soejima, H | 1 |
Ogawa, H | 2 |
Morimoto, T | 1 |
Okada, S | 1 |
Matsumoto, C | 1 |
Nakayama, M | 2 |
Masuda, I | 1 |
Jinnouchi, H | 1 |
Waki, M | 1 |
Saito, Y | 1 |
Zheng, J | 1 |
Xie, SH | 1 |
Santoni, G | 1 |
Lagergren, J | 1 |
Grant, PJ | 1 |
Cosentino, F | 1 |
Bressi, E | 1 |
Colaiori, I | 1 |
Capuano, M | 1 |
Viscusi, MM | 1 |
Spoto, S | 1 |
Barbato, E | 1 |
Di Sciascio, G | 1 |
Mafham, MM | 1 |
Bowman, LJ | 1 |
Haynes, RJ | 1 |
Armitage, JM | 1 |
David, C | 1 |
Costa, J | 1 |
Steg, PG | 7 |
Hohnloser, SH | 1 |
Nordaby, M | 1 |
Miede, C | 1 |
Kimura, T | 1 |
Lip, GYH | 1 |
Oldgren, J | 1 |
Ten Berg, JM | 1 |
Cannon, CP | 4 |
Verdoia, M | 5 |
Pergolini, P | 5 |
Nardin, M | 5 |
Rolla, R | 5 |
Negro, F | 2 |
Gioscia, R | 1 |
Fierro, N | 1 |
Saghir Afifeh, AM | 1 |
Viglione, F | 1 |
Suryapranata, H | 5 |
De Luca, G | 5 |
Sagar, RC | 1 |
Naseem, KM | 1 |
Ajjan, RA | 2 |
Eikelboom, JW | 4 |
Connolly, SJ | 3 |
Anand, SS | 3 |
Verma, S | 1 |
Branch, KRH | 2 |
Probstfield, J | 1 |
Bosch, J | 2 |
Shestakovska, O | 2 |
Szarek, M | 1 |
Maggioni, AP | 2 |
Widimský, P | 1 |
Avezum, A | 3 |
Diaz, R | 1 |
Lewis, BS | 1 |
Berkowitz, SD | 3 |
Fox, KAA | 4 |
Ryden, L | 1 |
Yusuf, S | 4 |
Mehta, SR | 1 |
Gibson, CM | 2 |
Chandiramani, R | 1 |
Oldroyd, KG | 1 |
Ya-Ling, H | 1 |
Sharma, S | 1 |
Shlofmitz, RA | 1 |
Clemens, KK | 1 |
Woodward, M | 1 |
Neal, B | 1 |
Zinman, B | 1 |
Shufelt, CL | 1 |
Manson, JE | 2 |
Serruys, PW | 1 |
Takahashi, K | 1 |
Chichareon, P | 1 |
Onuma, Y | 1 |
Patel, NJ | 1 |
Baliga, RR | 1 |
Wu, B | 1 |
Shi, L | 1 |
Ali, I | 1 |
Bazzar, A | 1 |
Hussein, N | 1 |
Sahhar, E | 1 |
Colak, B | 1 |
Orhan, A | 1 |
Ece, I | 1 |
Yormaz, S | 1 |
Yilmaz, H | 1 |
Sahin, M | 1 |
Boussofara, A | 1 |
Laroussi, L | 1 |
Baccouche, H | 1 |
Bennour, E | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Study of Cardiovascular Events iN Diabetes - A Randomized 2x2 Factorial Study of Aspirin Versus Placebo, and of Omega-3 Fatty Acid Supplementation Versus Placebo, for Primary Prevention of Cardiovascular Events in People With Diabetes[NCT00135226] | Phase 4 | 15,480 participants (Actual) | Interventional | 2005-03-31 | Active, not recruiting | ||
A head-to Head Comparison of the Pharmacodynamic Effects of Prasugrel Compared With Ticagrelor in Patients With Coronary Artery Disease[NCT01852175] | 110 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
Polypill Strategy for Evidence-Based Management of Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention in an Underserved Patient Population[NCT05514938] | Phase 2 | 60 participants (Anticipated) | Interventional | 2022-11-30 | Recruiting | ||
Effectiveness of Polypill for Primary Prevention of Cardiovascular Disease (PolyPars): Study Design and Rationale for a Pragmatic Cluster Randomized Controlled Trial[NCT03459560] | Phase 3 | 4,415 participants (Actual) | Interventional | 2015-12-20 | Active, not recruiting | ||
Fixed-dose Combination Therapy (PolyPill) in Primary and Secondary Prevention of Cardiovascular Disease in Middle-aged and Elderly Iranians[NCT01271985] | Phase 3 | 8,410 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
Polipill and RiscOMeter to Prevent StrOke and CogniTive ImpairmEnt in Primary Health Care[NCT05155137] | Phase 3 | 12,268 participants (Anticipated) | Interventional | 2021-12-20 | Recruiting | ||
A Randomized Controlled Trial of Rivaroxaban for the Prevention of Major Cardiovascular Events in Patients With Coronary or Peripheral Artery Disease (COMPASS - Cardiovascular OutcoMes for People Using Anticoagulation StrategieS).[NCT01776424] | Phase 3 | 27,395 participants (Actual) | Interventional | 2013-02-28 | Completed | ||
Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention[NCT02270242] | Phase 4 | 9,006 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
Performance du TiVi Pour évaluer la réactivité Microcirculatoire de la Peau à l'Application d'un Courant Galvanique, Effet de l'Aspirine[NCT03357367] | 830 participants (Actual) | Interventional | 2018-02-08 | Completed | |||
Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation: Multicenter Randomized Clinical Trial[NCT05283356] | Phase 4 | 1,206 participants (Anticipated) | Interventional | 2022-01-21 | Recruiting | ||
The Impact of Meal Timing on Neurovascular Control in Adults[NCT04133701] | 34 participants (Actual) | Interventional | 2022-02-02 | Completed | |||
Efficacy and Safety of Clopidogrel for Primary Prevention in Patients With Subclinical Coronary Atherosclerosis Identified on Imaging[NCT05845489] | Phase 4 | 9,930 participants (Anticipated) | Interventional | 2023-03-09 | Recruiting | ||
Aspirin Discontinuation After Left Atrial Appendage Occlusion in Atrial Fibrillation[NCT03821883] | 1,120 participants (Anticipated) | Interventional | 2020-06-01 | Recruiting | |||
Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II[NCT05702463] | Phase 1 | 30 participants (Anticipated) | Interventional | 2023-06-13 | Recruiting | ||
Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes: APPEASED Study Phase 1[NCT05105919] | Early Phase 1 | 50 participants (Anticipated) | Interventional | 2021-08-26 | Recruiting | ||
Study of the Effect of Eicosapentaenoic Acid (EPA) on Markers of Atherothrombosis in Patients With Type-2 Diabetes[NCT06129526] | Phase 4 | 450 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | ||
Japanese Primary Prevention Project With Aspirin in the Elderly With One or More Risk Factors of Vascular Events: JPPP[NCT00225849] | Phase 4 | 10,000 participants | Interventional | 2005-03-31 | Recruiting | ||
Randomized Evaluation of Long Term Anticoagulant Therapy (RE-LY) Comparing the Efficacy and Safety of Two Blinded Doses of Dabigatran Etexilate With Open Label Warfarin for the Prevention of Stroke and Systemic Embolism in Patients With Non-valvular Atria[NCT00262600] | Phase 3 | 18,113 participants (Actual) | Interventional | 2005-12-31 | Completed | ||
A Monitor System for the Safety of Dabigatran Anticoagulation Treatment in Nonvalvular Atrial Fibrillation[NCT02414035] | 1,496 participants (Actual) | Observational | 2015-03-22 | Completed | |||
A Multi-center, Randomized, Double-blind and Placebo-controlled Clinical Research of 2200 Cases in Improving Curative Effect of Secondary Prevention for Patients With Ischemic Stroke Through Syndrome Differentiation of TCM[NCT02334969] | Phase 4 | 2,200 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
The Impact of Aspirin Dose Modification on the Innate Immune Response - Will Lower Dose Aspirin Therapy Reduce the Response to Endotoxin[NCT03869268] | Phase 4 | 72 participants (Actual) | Interventional | 2019-04-24 | Completed | ||
Aspirin Withdrawal and Clinical Outcome in Patients With Moderate to High Cardiovascular Risk But Without Cardiovascular Disease[NCT03757156] | 4,118 participants (Anticipated) | Interventional | 2019-03-31 | Not yet recruiting | |||
A Multicenter Randomized Trial Evaluating the Efficacy of Sarpogrelate on Ischemic Heart Disease After Drug-eluting Stent Implantation in Patients With Diabetes Mellitus or Renal Impairment[NCT02294643] | Phase 3 | 220 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
Dissemination of CVD Risk Factor Treatment Among Diabetic Patients in Safety Net Clinics[NCT02299791] | 4,856 participants (Actual) | Interventional | 2010-09-30 | Completed | |||
Adaptation of an eHealth (Web-application) Platform for Delivery of a Sedentary Behavior Intervention Among Prostate Cancer Patients[NCT03740035] | 4 participants (Actual) | Observational | 2018-08-13 | Terminated (stopped due to Pl left institution) | |||
A Prospective, Multi-center, Randomized, Double-blind Trial to Assess the Effectiveness and Safety of 12 Versus 30 Months of Dual Antiplatelet Therapy in Subjects Undergoing Percutaneous Coronary Intervention With Either Drug-eluting Stent or Bare Metal S[NCT00977938] | Phase 4 | 25,682 participants (Actual) | Interventional | 2009-10-31 | Completed | ||
Personalization of Long-Term Antiplatelet Therapy Using a Novel Combined Demographic/Pharmacogenomic Strategy - The RAPID EXTEND Randomized Study[NCT03729401] | Phase 4 | 390 participants (Anticipated) | Interventional | 2019-08-22 | Suspended (stopped due to Testing supplies unavailable.) | ||
Randomized 2x2 Factorial Trial Comparing the Cre8 Amphilimus-sirolimus Eluting Stent vs. the Synergy Everolimus-eluting Stent and a Personalized vs. Standard Duration of Dual Antiplatelet Therapy in All-comers Patients Undergoing Percutaneous Coronary Int[NCT04135989] | Phase 4 | 2,106 participants (Anticipated) | Interventional | 2020-01-01 | Active, not recruiting | ||
Patterns of Non-Adherence to Dual Anti-Platelet Regimen In Stented Patients: An Observational Single-Arm Study (The PARIS Registry)[NCT00998127] | 5,031 participants (Actual) | Observational | 2009-06-30 | Completed | |||
The Role of Multiple Electrode Aggregometry in Detection of Clopidogrel Resistance in Diabetic Patients With Coronary Artery Disease and Prediction of Clinical Outcomes. A Comparative-method, Non Interventional, Single Center Study.[NCT01991093] | 280 participants (Actual) | Observational | 2014-06-30 | Completed | |||
Platelet Reactivity in Patients With Chronic Kidney Disease Receiving Adjunctive Cilostazol Compared to a High-maintenance Dose of Clopidogrel[NCT01328470] | Phase 4 | 85 participants (Actual) | Interventional | 2009-09-30 | Completed | ||
Effects of Pioglitazone on Platelet Function[NCT00861341] | Phase 2 | 40 participants (Actual) | Interventional | 2008-12-31 | Completed | ||
Multi-Center Registry Trial of EXCEL Biodegradable Polymer Drug-Eluting Stent[NCT00331578] | Phase 4 | 2,077 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
Identifying and Overcoming Barriers to Diabetes Management in the Elderly: An Intervention Study[NCT01480804] | 48 participants (Actual) | Interventional | 2006-11-30 | Completed | |||
Identifying and Overcoming Barriers to Diabetes Management in the Elderly: A Cost-effective Intervention Study[NCT01486290] | 52 participants (Actual) | Interventional | 2007-07-31 | Completed | |||
A Randomized, Open-label, Active-controlled, Parallel-group Study to Investigate the Platelet Inhibition of Ticagrelor Versus Clopidogrel in Patients With Stable Coronary Artery Disease and Type 2 Diabetes Mellitus After Recent Elective Percutaneous Coron[NCT02748330] | Phase 4 | 40 participants (Actual) | Interventional | 2016-06-30 | Completed | ||
SEA-SIDE: Sirolimus Versus Everolimus-eluting Stent Randomized Assessment in Bifurcated Lesions and Clinical SIgnificance of Residual siDE-branch Stenosis[NCT00697372] | Phase 4 | 150 participants (Actual) | Interventional | 2007-09-30 | Completed | ||
Prospective Randomized Study of the Paclitaxel-Coated Balloon Catheter in Bifurcated Coronary Lesions / BABILON Study (Paclitaxel-Coated Balloon in Bifurcated Lesions)[NCT01278186] | Phase 4 | 190 participants (Anticipated) | Interventional | 2010-06-30 | Active, not recruiting | ||
Prospective, Randomized, Single-Center Evaluation of the Cypher™ Sirolimus Eluting Coronary Stent System in the Treatment of Bifurcated Coronary Lesions[NCT00288535] | Phase 4 | 200 participants (Anticipated) | Interventional | 2005-03-31 | Recruiting | ||
Study of Lipid Core Plaque Shift at Sites of Native Coronary Artery Bifurcation[NCT00905671] | Phase 4 | 20 participants (Actual) | Interventional | 2009-06-30 | Completed | ||
Z-SEA-SIDE: Sirolimus Versus Everolimus Versus Zotarolimus-eluting Stent Assessment in Bifurcated Lesions and Clinical SIgnificance of Residual siDE-branch Stenosis[NCT01200693] | Phase 4 | 80 participants (Actual) | Interventional | 2008-11-30 | Completed | ||
Approaches to Chronic Occlusions With Sirolimus Stents-Cypher (ACROSS-Cypher) Total Occlusion Study of Coronary Arteries 4 Trial[NCT00378612] | Phase 3 | 200 participants (Actual) | Interventional | 2005-06-30 | Completed | ||
Can the Lambre Device Occlude IRRegular And Large Appendages in Patients With Non-Valvular AF: The CORRAL-AF Study[NCT04684212] | 2,931 participants (Anticipated) | Interventional | 2023-12-01 | Not yet recruiting | |||
Comparison of Platelet Inhibitory Effect With Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction Patients According to CYP2C19 Polymorphism[NCT00915733] | Phase 4 | 80 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
[NCT00000151] | Phase 3 | 0 participants | Interventional | 1979-12-31 | Completed | ||
THE OMEGA-SPM-DOSE and OMEGA-SPM-PAD: Specialized Pro-Resolving Mediators in Patients With Peripheral Artery Disease[NCT02719665] | 30 participants (Actual) | Interventional | 2016-03-31 | Completed | |||
Arterial Imaging of Inflammation and Resolution After Endovascular Surgery[NCT03590769] | Phase 1 | 9 participants (Actual) | Interventional | 2017-06-01 | Completed | ||
Do Innovative Strategies Complement Medical Management to Reduce Cardiovascular Risk Factors Following Coronary Artery Bypass Graft Surgery?[NCT00462436] | Phase 2 | 35 participants (Anticipated) | Interventional | 2007-02-28 | Completed | ||
Procedure and In-hospital Outcome of Patients Under 40 Years Old Undergoing Primary Percutaneous Coronary Intervention for Acute ST Elevated Myocardial Infarction in Assiut University[NCT03266328] | 117 participants (Anticipated) | Observational | 2017-09-01 | Not yet recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"Secondary efficacy assessments of aspirin involve intention-to-treat comparisons during the scheduled treatment period among all randomized participants on the first occurrence of:~Any incident gastrointestinal (GI) tract cancer (i.e. any GI cancer excluding pancreas and hepatobiliary), overall and after exclusion of the first three years of follow-up." (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 157 |
Placebo Aspirin | 158 |
"Secondary efficacy assessments involve intention-to-treat comparisons among all randomized participants of allocation to aspirin versus placebo and, separately, of omega-3 versus placebo on the first occurrence of the expanded vascular endpoint of SVE or revascularization (including coronary and non-coronary revascularizations)." (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 833 |
Placebo Aspirin | 936 |
Omega-3 | 882 |
Placebo Omega-3 | 887 |
"Incidence of fatal or non-fatal cancers. Any cancer excludes non-fatal non-melanoma skin cancer and non-fatal recurrence of a cancer that had occurred before randomization.~A single participant may have had multiple cancers." (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 897 |
Placebo Aspirin | 887 |
Omega-3 | 894 |
Placebo Omega-3 | 890 |
Includes fatal and non-fatal events. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Omega-3 | 166 |
Placebo Omega-3 | 135 |
Includes fatal and non-fatal cancers. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 97 |
Placebo Aspirin | 96 |
Omega-3 | 103 |
Placebo Omega-3 | 90 |
Includes fatal and non-fatal renal, bladder, prostate, gynaecological and other GU cancers (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 332 |
Placebo Aspirin | 294 |
Omega-3 | 323 |
Placebo Omega-3 | 303 |
Includes fatal and non-fatal cancers. Includes leukaemia and lymphoma. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 88 |
Placebo Aspirin | 86 |
Omega-3 | 94 |
Placebo Omega-3 | 80 |
Includes fatal and non-fatal melanomas. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 50 |
Placebo Aspirin | 59 |
Omega-3 | 55 |
Placebo Omega-3 | 54 |
Includes fatal and non-fatal events, excludes atrial fibrillation. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Omega-3 | 83 |
Placebo Omega-3 | 99 |
Includes fatal and non-fatal cancers not included elsewhere (where the type of cancer is known). (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 25 |
Placebo Aspirin | 30 |
Omega-3 | 23 |
Placebo Omega-3 | 32 |
Includes fatal and non-fatal cancers. Excludes cancers reported in the gastrointestinal tract category (see secondary outcome measure #4), and includes hepatobiliary and pancreatic cancers. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 87 |
Placebo Aspirin | 82 |
Includes fatal and non-fatal cancers. Includes lung and larynx cancer. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 101 |
Placebo Aspirin | 103 |
Omega-3 | 104 |
Placebo Omega-3 | 100 |
Includes fatal and non-fatal cancers of unknown type. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 26 |
Placebo Aspirin | 31 |
Omega-3 | 25 |
Placebo Omega-3 | 32 |
Fatal 'All stroke' events include deaths from: Haemorrhagic stroke (Intracerebral haemorrhage; Subarachnoid haemorrhage); Non-haemorrhagic stroke (Cerebral infarction; Stroke not specified as haemorrhage or infarction). (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 38 |
Placebo Aspirin | 34 |
Omega-3 | 35 |
Placebo Omega-3 | 37 |
'All-cause mortality' includes all recorded deaths. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 748 |
Placebo Aspirin | 792 |
Omega-3 | 752 |
Placebo Omega-3 | 788 |
Fatal 'Cancer' events include any death attributed to cancer. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 309 |
Placebo Aspirin | 315 |
Omega-3 | 305 |
Placebo Omega-3 | 319 |
Fatal 'Coronary' events include deaths from: Acute MI and other CHD (unspecified Acute ischaemic heart disease; Atherosclerotic heart disease; Ischaemic cardiomyopathy; unspecified Chronic ischaemic heart disease). (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 105 |
Placebo Aspirin | 122 |
Omega-3 | 100 |
Placebo Omega-3 | 127 |
Fatal 'External cause' events include deaths from: Injury; Fracture; Self harm; and Medical and surgical complications (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 18 |
Placebo Aspirin | 21 |
Omega-3 | 17 |
Placebo Omega-3 | 22 |
Fatal 'Other medical' events include deaths from: Non-vascular medical causes (excluding cancer and respiratory, including Fatal GI bleed or perforation); and deaths from Renal disease and Diabetes. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 126 |
Placebo Aspirin | 157 |
Omega-3 | 158 |
Placebo Omega-3 | 125 |
Fatal 'Other vascular' events include deaths from: Heart failure (excluding ischaemic cardiomyopathy); Other vascular death (excluding stroke; and Cardiac death (excluding CHD). (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 67 |
Placebo Aspirin | 70 |
Omega-3 | 61 |
Placebo Omega-3 | 76 |
Fatal 'Respiratory' events include any death attributed to respiratory causes. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 82 |
Placebo Aspirin | 69 |
Omega-3 | 73 |
Placebo Omega-3 | 78 |
Any death for which the cause is not known. (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 3 |
Placebo Aspirin | 4 |
Omega-3 | 3 |
Placebo Omega-3 | 4 |
"The primary safety assessments involve intention-to-treat comparisons among all randomized patients of allocation to aspirin versus placebo on the first occurrence of any major bleed, defined as:~any confirmed intracranial hemorrhage (including intracerebral, subarachnoid, subdural or any other intracranial hemorrhage); or~sight-threatening eye bleeding; or~any other serious bleeding episode." (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 314 |
Placebo Aspirin | 245 |
"The primary efficacy assessments involve intention-to-treat comparisons among all randomized participants of allocation to aspirin versus placebo and, separately, of omega-3 fatty acids versus placebo on the first occurrence of any Serious Vascular Event (SVE), defined as:~non-fatal myocardial infarction; or~non-fatal stroke (excluding confirmed intracranial hemorrhage) or TIA; or~vascular death excluding confirmed intracranial hemorrhage (defined as International Classification of Diseases 10th revision [ICD-10] I00-52 or I63-99, i.e. excluding subarachnoid hemorrhage [I60], intracerebral hemorrhage [I61], and other non-traumatic intracranial hemorrhage [I62])." (NCT00135226)
Timeframe: Randomized treatment phase during a mean of 7.4 years
Intervention | Participants (Count of Participants) |
---|---|
Aspirin | 658 |
Placebo Aspirin | 743 |
Omega-3 | 689 |
Placebo Omega-3 | 712 |
The primary end-point of the study was the comparison in the platelet reactivity index (PRI%) determined by vasodilator-stimulated phosphoprotein (VASP) at 1 week between prasugrel and ticagrelor. (NCT01852175)
Timeframe: 1 week
Intervention | PRI% (Least Squares Mean) |
---|---|
Prasugrel | 32.1 |
Ticagrelor | 32.6 |
A secondary outcome was the comparison between groups of platelet reactivity index (PRI) measured by vasodilator-stimulated phosphoprotein (VASP) at 2 hours after loading dose. (NCT01852175)
Timeframe: 2 hours
Intervention | PRI% (Least Squares Mean) |
---|---|
Prasugrel | 13.4 |
Ticagrelor | 15.6 |
A secondary outcome was the comparison between groups of platelet reactivity index (PRI) measured by vasodilator-stimulated phosphoprotein (VASP) at 24 hours after loading dose. (NCT01852175)
Timeframe: 24 hours
Intervention | PRI% (Least Squares Mean) |
---|---|
Prasugrel | 14.2 |
Ticagrelor | 26.4 |
Count of participants and time from randomization to death by all cause were evaluated. Hazard ratios were calculated and reported as statistical analysis. (NCT01776424)
Timeframe: For each participants, death by any cause after randomization up until the global rivaroxaban/aspirin outcomes cut-off date (06 FEB 2017) was considered. The mean time in follow-up until that date was 702 days.
Intervention | Participants (Count of Participants) |
---|---|
Rivaroxaban 2.5mg + Aspirin 100mg | 313 |
Rivaroxaban 5mg + Aspirin Placebo | 366 |
Rivaroxaban Placebo + Aspirin 100mg | 378 |
Count of participants from COMPASS LTOLE initiation visit to death by all cause were evaluated. LTOLE: long-term open-lable extension (NCT01776424)
Timeframe: For each participants, death by any cause after COMPASS LTOLE initiation visit up until the the last LTOLE part contact date was considered. The mean time in follow-up until that date was 428 days.
Intervention | Participants (Count of Participants) |
---|---|
LTOLE Part: Rivaroxaban 2.5mg + Aspirin 100mg | 282 |
Count of participants and time from randomization to the first occurrence of MI, ischemic stroke, ALI, or CV death were evaluated. Hazard ratios were calculated and reported as statistical analysis. (NCT01776424)
Timeframe: For each participant, the first occurrence of MI, ischemic stroke, ALI, or CV death after randomization up until the global rivaroxaban/aspirin outcomes cut-off date (06 FEB 2017) was considered. The mean time in follow-up until that date was 702 days.
Intervention | Participants (Count of Participants) |
---|---|
Rivaroxaban 2.5mg + Aspirin 100mg | 389 |
Rivaroxaban 5mg + Aspirin Placebo | 453 |
Rivaroxaban Placebo + Aspirin 100mg | 516 |
Count of participants and time from randomization to the first occurrence of MI, ischemic stroke, ALI, or CHD death were evaluated. Hazard ratios were calculated and reported as statistical analysis. (NCT01776424)
Timeframe: For each participant, the first occurrence of MI, ALI, or CHD death after randomization up until the global rivaroxaban/aspirin outcomes cut-off date (06 FEB 2017) was considered. The mean time in follow-up until that date was 702 days.
Intervention | Participants (Count of Participants) |
---|---|
Rivaroxaban 2.5mg + Aspirin 100mg | 329 |
Rivaroxaban 5mg + Aspirin Placebo | 397 |
Rivaroxaban Placebo + Aspirin 100mg | 450 |
Count of participants and time from randomization to the first occurrence of the composite primary efficacy outcome, MI, stroke, or CV death were evaluated. Hazard ratios were calculated and reported as statistical analysis. (NCT01776424)
Timeframe: For each participant, the first occurrence of the composite primary efficacy outcome after randomization up until the global rivaroxaban/aspirin outcomes cut-off date (06 FEB 2017) was considered. The mean time in follow-up until that date was 702 days.
Intervention | Participants (Count of Participants) |
---|---|
Rivaroxaban 2.5mg + Aspirin 100mg | 379 |
Rivaroxaban 5mg + Aspirin Placebo | 448 |
Rivaroxaban Placebo + Aspirin 100mg | 496 |
Count of participants from COMPASS LTOLE initiation visit to the first occurrence of the composite primary efficacy outcome, MI, stroke, or CV death were evaluated. LTOLE: long-term open-lable extension (NCT01776424)
Timeframe: For each participant, the first occurrence of the composite primary efficacy outcome after from COMPASS LTOLE initiation visit up until last LTOLE part contact date was considered. The mean time in follow-up was 428 days.
Intervention | Participants (Count of Participants) |
---|---|
LTOLE Part: Rivaroxaban 2.5mg + Aspirin 100mg | 353 |
"Modified ISTH major bleeding is defined as: i) Fatal bleeding, or ii) Symptomatic bleeding in a critical area or organ, such as intraarticular, intracranial, intramuscular with compartment syndrome, intraocular, intraspinal, liver, pancreas, pericardial, respiratory, retroperitoneal, adrenal gland or kidney; or bleeding into the surgical site requiring reoperation, or iii) Bleeding leading to hospitalization (major bleeding also includes presentation to an acute care facility with discharge on the same day).~Count of participants and time from randomization to the first occurrence of the primary safety outcome major bleeding were evaluated. Hazard ratios were calculated and reported as statistical analysis." (NCT01776424)
Timeframe: For each participant, the first occurrence of modified ISTH major bleeding after randomization up until the global rivaroxaban/aspirin outcomes cut-off date (06 FEB 2017) was considered. The mean time in follow-up until that date was 702 days.
Intervention | Participants (Count of Participants) |
---|---|
Rivaroxaban 2.5mg + Aspirin 100mg | 288 |
Rivaroxaban 5mg + Aspirin Placebo | 255 |
Rivaroxaban Placebo + Aspirin 100mg | 170 |
"Modified ISTH major bleeding is defined as: i) Fatal bleeding, or ii) Symptomatic bleeding in a critical area or organ, such as intraarticular, intracranial, intramuscular with compartment syndrome, intraocular, intraspinal, liver, pancreas, pericardial, respiratory, retroperitoneal, adrenal gland or kidney; or bleeding into the surgical site requiring reoperation, or iii) Bleeding leading to hospitalization (major bleeding also includes presentation to an acute care facility with discharge on the same day).~Count of participants from COMPASS LTOLE initiation visit to the first occurrence of the primary safety outcome major bleeding was evaluated. LTOLE: long-term open-lable extension" (NCT01776424)
Timeframe: For each participant, the first occurrence of modified ISTH major bleeding from COMPASS LTOLE initiation visit up until 2 days after the last treatment in LTOLE part was considered. The mean time in follow-up was 421 days.
Intervention | Participants (Count of Participants) |
---|---|
LTOLE Part: Rivaroxaban 2.5mg + Aspirin 100mg | 138 |
Number of participants with first occurrence of clinically relevant bleeding episode, defined as Bleeding Academic Research Consortium (BARC) Types 2, 3 or 5 bleeding. BARC bleeding types range from 0 (no bleeding) to 5 (fatal bleeding). (NCT02270242)
Timeframe: 12 months after randomization
Intervention | Participants (Count of Participants) |
---|---|
Placebo + Ticagrelor | 141 |
Aspirin + Ticagrelor | 250 |
Number of participants with first occurrence of confirmed all-cause death, non-fatal myocardial infarction or stroke. (NCT02270242)
Timeframe: 12 months after randomization
Intervention | Participants (Count of Participants) |
---|---|
Placebo + Ticagrelor | 135 |
Aspirin + Ticagrelor | 137 |
Number of subjects with abnormal liver function test (LFT), i.e., ALT/AST>3xULN and total bilirubin > 2 x ULN (NCT00262600)
Timeframe: 36 months
Intervention | participants (Number) |
---|---|
Dabigatran 110 mg | 11 |
Dabigatran 150 mg | 14 |
Warfarin | 21 |
Time to first occurrence of stroke or systemic embolic event. Yearly event rate (%) = number of subjects with event / subject-years * 100. Subject years = sum(date of study termination - date of randomization + 1) of all randomized subjects / 365.25 (NCT00262600)
Timeframe: 36 months
Intervention | yearly event rate (percentage) (Number) |
---|---|
Dabigatran 110 mg | 1.54 |
Dabigatran 150 mg | 1.11 |
Warfarin | 1.71 |
Time to first occurrence of stroke, SEE or all cause death. Yearly event rate (%) = number of subjects with event / subject-years * 100. Subject years = sum(date of study termination - date of randomization + 1) of all randomized subjects / 365.25 (NCT00262600)
Timeframe: 36 months
Intervention | yearly event rate (percentage) (Number) |
---|---|
Dabigatran 110 mg | 4.85 |
Dabigatran 150 mg | 4.32 |
Warfarin | 5.20 |
Time to first occurrence of stroke, systemic embolic event, pulmonary embolism, myocardial infarction including silent myocardial infarction or vascular death. Yearly event rate (%) = number of subjects with event / subject-years * 100. Subject years = sum(date of study termination - date of randomization + 1) of all randomized subjects / 365.25 (NCT00262600)
Timeframe: 36 months
Intervention | yearly event rate (percentage) (Number) |
---|---|
Dabigatran 110 mg | 4.26 |
Dabigatran 150 mg | 3.68 |
Warfarin | 4.35 |
"Yearly event rate of bleeds. Yearly event rate (%) = number of subjects with event / subject-years * 100. Subject years = sum(date of study termination - date of randomization + 1) of all randomized subjects / 365.25~Major bleeds are adjudicated, whereas minor bleeds are investigator reported." (NCT00262600)
Timeframe: 36 months
Intervention | yearly event rate (percentage) (Number) | |
---|---|---|
Major bleeds | Minor bleeds | |
Dabigatran 110 mg | 2.99 | 13.16 |
Dabigatran 150 mg | 3.55 | 14.85 |
Warfarin | 3.81 | 16.37 |
Patients with clinical relevant abnormalities for intracerebral hemorrhage, other intracranial hemorrhage (ICH) (NCT00262600)
Timeframe: 36 months
Intervention | yearly event rate (percentage)] (Number) | |
---|---|---|
intracerebral hemorrhage | intracranial hemorrhage (ICH) | |
Dabigatran 110 mg | 0.12 | 0.23 |
Dabigatran 150 mg | 0.10 | 0.32 |
Warfarin | 0.38 | 0.76 |
Number of patients indicated for ACE/ARB and statin who had an active prescription for both, as a proportion of patients indicated for ACE/ARB and statin. (NCT02299791)
Timeframe: Percent of clinic patients prescribed guideline-concordant cardioprotective medications, as of the 1st day of each month, from up to 36 months
Intervention | Participants (Count of Participants) |
---|---|
Early Intervention | 1279 |
Late Implementation | 1318 |
Secondary powered endpoint (NCT00977938)
Timeframe: 33 months (0-33 months post-index procedure)
Intervention | percentage of patients (Number) |
---|---|
Propensity-matched DES | 1.70 |
Propensity-matched BMS | 2.61 |
ST was assessed according to the Academic Research Consortium (ARC) definitions. (NCT00977938)
Timeframe: 18 months (12-30 months post-index procedure)
Intervention | percentage of patients (KM estimate) (Number) |
---|---|
BMS 30-month DAPT | 0.50 |
BMS 12-month DAPT | 1.11 |
ST was assessed according to the Academic Research Consortium (ARC) definitions. (NCT00977938)
Timeframe: 21 months (12-33 months post-index procedure)
Intervention | percentage of patients (KM estimate) (Number) |
---|---|
BMS 30-month DAPT | 0.50 |
BMS 12-month DAPT | 1.11 |
ST was assessed according to the Academic Research Consortium (ARC) definitions. (NCT00977938)
Timeframe: 21 months (12-33 months post-index procedure)
Intervention | percentage of patients (KM estimate) (Number) |
---|---|
DES 30-month DAPT | 0.69 |
DES 12-month DAPT | 1.45 |
The coprimary efficacy endpoints were the cumulative incidence of MACCE and the cumulative incidence of definite or probable ST within randomized DES ITT patients between 12 and 30 months post procedure. ST was assessed according to the Academic Research Consortium (ARC) definitions. (NCT00977938)
Timeframe: 18 months (12-30 months post-index procedure)
Intervention | percentage of patients (KM estimate) (Number) |
---|---|
DES 30-month DAPT | 0.40 |
DES 12-month DAPT | 1.35 |
Bleeding was assessed according to the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Arteries (GUSTO) criteria. (NCT00977938)
Timeframe: 18 months (12-30 months post-index procedure)
Intervention | percentage of patients (Number) |
---|---|
BMS 30-month DAPT | 2.03 |
BMS 12-month DAPT | 0.90 |
Bleeding was assessed according to the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Arteries (GUSTO) criteria. (NCT00977938)
Timeframe: 21 months (12-33 months post-index procedure)
Intervention | percentage of patients (Number) |
---|---|
BMS 30-month DAPT | 2.09 |
BMS 12-month DAPT | 1.05 |
Bleeding was assessed according to the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Arteries (GUSTO) criteria. (NCT00977938)
Timeframe: 21 months (12-33 months post-index procedure)
Intervention | percentage of patients (Number) |
---|---|
DES 30-month DAPT | 2.74 |
DES 12-month DAPT | 1.88 |
The primary safety endpoint was moderate or severe bleeding within randomized DES ITT patients between 12 and 30 months post procedure. Bleeding was assessed according to the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Arteries (GUSTO) criteria. (NCT00977938)
Timeframe: 18 months (12-30 months post-index procedure)
Intervention | percentage of patients (Number) |
---|---|
DES 30-month DAPT | 2.53 |
DES 12-month DAPT | 1.57 |
Secondary powered endpoint (NCT00977938)
Timeframe: 33 months (0-33 months post-index procedure)
Intervention | percentage of patients (Number) |
---|---|
Propensity-matched DES | 11.37 |
Propensity-matched BMS | 13.24 |
(NCT00977938)
Timeframe: 18 months (12-30 months post-index procedure)
Intervention | percentage of patients (KM estimate) (Number) |
---|---|
BMS 30-month DAPT | 4.04 |
BMS 12-month DAPT | 4.69 |
(NCT00977938)
Timeframe: 21 months (12-33 months post-index procedure)
Intervention | percentage of patients (KM estimate) (Number) |
---|---|
BMS 30-month DAPT | 4.68 |
BMS 12-month DAPT | 5.48 |
(NCT00977938)
Timeframe: 21 months (12-33 months post-index procedure)
Intervention | percentage of patients (KM estimate) (Number) |
---|---|
DES 30-month DAPT | 5.62 |
DES 12-month DAPT | 6.49 |
The coprimary efficacy endpoints were the cumulative incidence of MACCE and the cumulative incidence of ARC definite or probable stent thrombosis within randomized DES ITT patients between 12 and 30 months post procedure. (NCT00977938)
Timeframe: 18 months (12-30 months post-index procedure)
Intervention | percentage of patients (KM estimate) (Number) |
---|---|
DES 30-month DAPT | 4.34 |
DES 12-month DAPT | 5.92 |
Platelet aggregation was performed by the turbidimetric method of Born with simultaneous measurement of ATP release using a Chrono-log Lumi-Aggregometer with AGGRO/LINK for Windows Software version 5.1.6. Platelet rich plasma was placed in a silicone-coated cuvette with constant stirring at 1200 rpm using a siliconized stir bar for measurement of aggregation and ATP release. Aggregation was initiated using arachidonic acid (0.5 mM). At each time point the results are shown for maximum percent aggregation with arachidonic acid for all subjects. Sample 1 was obtained at baseline (BL). Sample 2 was drawn on the same day after ingestion of a single dose of 30 mg of pioglitazone. Sample 3 was obtained 6-9 days later after the subject had ingested a single 81 mg dose of aspirin (ASA), and sample 4 was drawn later that day after ingestion of 30 mg of pioglitazone. (NCT00861341)
Timeframe: at baseline and days 6-9
Intervention | maximum percentage aggregation (Mean) | |||
---|---|---|---|---|
Sample 1 | Sample 2 | Sample 3 | Sample 4 | |
Pioglitazone With or Without 81mg Aspirin | 80 | 90 | 60 | 29 |
Platelet aggregation was performed by the turbidimetric method of Born with simultaneous measurement of ATP release using a Chrono-log Lumi-Aggregometer with AGGRO/LINK for Windows Software version 5.1.6. Platelet rich plasma was placed in a silicone-coated cuvette with constant stirring at 1200 rpm using a siliconized stir bar for measurement of aggregation and ATP release. Aggregation was initiated using collagen (2ug.mL). At each time point the results are shown for maximum percent aggregation with collagen for all subjects. Sample 1 was obtained at baseline (BL). Sample 2 was drawn on the same day after ingestion of a single dose of 30 mg of pioglitazone. Sample 3 was obtained 6-9 days later after the subject had ingested a single 81 mg dose of aspirin (ASA), and sample 4 was drawn later that day after ingestion of 30 mg of pioglitazone. (NCT00861341)
Timeframe: baseline and day 6-9
Intervention | maximum percentage aggregation (Mean) | |||
---|---|---|---|---|
Sample 1 | Sample 2 | Sample 3 | Sample 4 | |
Pioglitazone With or Without 81mg Aspirin | 89 | 93 | 83 | 78 |
99 reviews available for aspirin and Diabetes Mellitus
Article | Year |
---|---|
Is meta-analysis the optimal method to decide the duration of antiplatelet therapy in diabetic patients treated with drug‑eluting stenting?
Topics: Aspirin; Diabetes Mellitus; Humans; Pharmaceutical Preparations; Platelet Aggregation Inhibitors; St | 2021 |
Aspirin for the prevention of pre-eclampsia in women with pre-existing diabetes: Systematic review.
Topics: Aspirin; Diabetes Mellitus; Female; Humans; Pre-Eclampsia; Pregnancy | 2022 |
Aspirin, metformin, and statin use on the risk of gastric cancer: A nationwide population-based cohort study in Korea with systematic review and meta-analysis.
Topics: Aspirin; Cohort Studies; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; | 2022 |
Low-doses aspirin in the primary prevention of cardiovascular disease in patients with diabetes: Meta-analysis stratified by baseline cardiovascular risk.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Heart Disease Risk Factors; Humans; Primary Pre | 2022 |
Aspirin for Primary Cardiovascular Prevention in Patients with Diabetes: Uncertainties and Opportunities.
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Diabetes Mellitus; Humans; Platelet Aggregation I | 2022 |
Benefits and Risks Associated with Low-Dose Aspirin Use for the Primary Prevention of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Randomized Control Trials and Trial Sequential Analysis.
Topics: Aged; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Gastrointestinal Hemorrhage; Humans; Intr | 2022 |
Aspirin for Primary Prevention of Cardiovascular Diseases: "WALTZ" with the Evidence.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Primary Prevention; Risk Factors | 2022 |
In vivo degradation forms, anti-degradation strategies, and clinical applications of therapeutic peptides in non-infectious chronic diseases.
Topics: Amino Acids; Aspirin; Diabetes Mellitus; Humans; Insulins; Noncommunicable Diseases; Peptides; Polye | 2022 |
Questions and answers on the use of aspirin for primary prevention of cardiovascular disease in diabetes.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Primary Prevention; Risk Assessment | 2022 |
Acetylsalicylic Acid (Aspirin) for Primary Prevention of Cardiovascular Events in Patients with Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Hemorrhage; Humans; Myocardial Infarction; Prim | 2023 |
Aspirin and Primary Prevention in Patients with Diabetes-A Critical Evaluation of Available Randomized Trials and Meta-Analyses.
Topics: Anticoagulants; Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Diabetes Complications; D | 2019 |
Streamlined mail-based methods for large randomised trials: lessons learnt from the ASCEND study.
Topics: Animals; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Fatty Acids, Omega-3; Female; Humans; | 2020 |
Aspirin in the primary prevention of cardiovascular disease on diabetic patients: Systematic review and meta-analysis.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors; Primar | 2020 |
Antiplatelet therapies in diabetes.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus; Humans; Platelet Aggregation Inhib | 2020 |
Sex Disparities in Cardiovascular Outcome Trials of Populations With Diabetes: A Systematic Review and Meta-analysis.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Dis | 2020 |
Role of Aspirin for Primary Prevention in Persons with Diabetes Mellitus and in the Elderly.
Topics: Aged; Aspirin; Cardiovascular Diseases; Case-Control Studies; Diabetes Complications; Diabetes Melli | 2020 |
The Use of Aspirin in Contemporary Primary Prevention of Atherosclerotic Cardiovascular Diseases Revisited: The Increasing Need and Call for a Personalized Therapeutic Approach.
Topics: Aspirin; Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitus; Dose-Response Relationship, Dr | 2021 |
Dual therapy with an oral non-vitamin K antagonist and a P2Y12 inhibitor vs triple therapy with aspirin, a P2Y12 inhibitor and a vitamin K antagonist for the treatment of diabetes mellitus patients with co-existing atrial fibrillation following percutaneo
Topics: 4-Hydroxycoumarins; Aged; Aspirin; Atrial Fibrillation; Diabetes Mellitus; Diabetic Cardiomyopathies | 2021 |
Aspirin for Primary Prevention.
Topics: Age Factors; Aspirin; Cardiovascular Diseases; Colorectal Neoplasms; Diabetes Mellitus; Gastrointest | 2017 |
The pathogenesis and available prevention options in patients with diabetic thrombophilia.
Topics: Aspirin; Blood Coagulation; Diabetes Mellitus; Fibrinolysis; Humans; Hypoglycemic Agents; Thrombophi | 2018 |
[Importance of acetylsalicylic acid in primary prevention : ASCEND, ARRIVE and ASPREE as well as a meta-analysis by Rothwell et al.]
Topics: Aspirin; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors; Primary Prevention | 2019 |
Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Female; Hemorrhage; Hum | 2019 |
Aspirin for primary prevention of cardiovascular outcomes in diabetes mellitus: An updated systematic review and meta-analysis.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Humans; Platelet Aggrega | 2020 |
Topics: Aspirin; Cardiovascular Diseases; Cause of Death; Diabetes Mellitus; Humans; Platelet Aggregation In | 2019 |
Aspirin has potential benefits for primary prevention of cardiovascular outcomes in diabetes: updated literature-based and individual participant data meta-analyses of randomized controlled trials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Agents; Cardiovascular Diseases; | 2019 |
An aspirin a day? Clinical utility of aspirin therapy for the primary prevention of cardiovascular disease.
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Hemorrhage; Humans; Practice Guide | 2019 |
Dual antiplatelet therapy in patients with diabetes mellitus: special considerations.
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Diabetes Mellitus; Diabetic Angiopat | 2013 |
Review of guidelines on primary prevention of cardiovascular disease with aspirin: how much evidence is needed to turn a tanker?
Topics: Aspirin; Cardiology; Cardiovascular Agents; Cardiovascular Diseases; Diabetes Mellitus; Evidence-Bas | 2014 |
[Prevention of atherosclerosis in children--the role of statins and aspirin].
Topics: Adult; Aspirin; Atherosclerosis; Child; Comorbidity; Diabetes Mellitus; Dyslipidemias; Humans; Hydro | 2013 |
Factors influencing the decline in stroke mortality: a statement from the American Heart Association/American Stroke Association.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Air Pollution; American Heart Association; | 2014 |
Aspirin for primary prevention of cardiovascular events: meta-analysis of randomized controlled trials and subgroup analysis by sex and diabetes status.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Male; Placebos; Publication Bia | 2014 |
Cardiovascular Effects of Androgen Deprivation Therapy for the Treatment of Prostate Cancer: ABCDE Steps to Reduce Cardiovascular Disease in Patients With Prostate Cancer.
Topics: Aged; Androgen Antagonists; Aspirin; Blood Pressure; Cardiovascular Diseases; Cholesterol; Diabetes | 2016 |
Repositioning of Drugs in Cardiometabolic Disorders: Importance and Current Scenario.
Topics: Allopurinol; Aspirin; Bromocriptine; Cardiovascular Diseases; Clonidine; Colesevelam Hydrochloride; | 2016 |
The effectiveness of antioxidant therapy in aspirin resistance, diabetes population for prevention of thrombosis.
Topics: Antioxidants; Aspirin; Blood Platelets; Diabetes Mellitus; Humans; Thrombosis; Treatment Outcome | 2016 |
Aspirin for primary prevention of cardiovascular disease in patients with diabetes: A meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Diabetes Complications; D | 2016 |
Aspirin resistance: disparities and clinical implications.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Coronary Artery Bypass; Diabetes Mellitus; | 2008 |
A practical "ABCDE" approach to the metabolic syndrome.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Diet Therapy; Early Diagnosis; Evidence-Based M | 2008 |
Resistance to aspirin and thienopyridines in diabetes mellitus and metabolic syndrome.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Drug Resistance; Humans; Metabolic Syndrome; Pl | 2008 |
Diabetes, vascular complications and antiplatelet therapy: open problems.
Topics: Aspirin; Clopidogrel; Diabetes Mellitus; Diabetic Angiopathies; Drug Interactions; Drug Resistance; | 2009 |
Antiplatelet therapy in diabetes: efficacy and limitations of current treatment strategies and future directions.
Topics: Aspirin; Clopidogrel; Diabetes Mellitus; Diabetic Angiopathies; Drug Resistance; Humans; Platelet Ac | 2009 |
Diabetes and acute coronary syndromes.
Topics: Acute Coronary Syndrome; Anticoagulants; Aspirin; Blood Glucose; Clopidogrel; Diabetes Mellitus; Dia | 2009 |
Aspirin and clopidogrel: efficacy and resistance in diabetes mellitus.
Topics: Aspirin; Clopidogrel; Diabetes Mellitus; Drug Resistance; Endothelium, Vascular; Humans; Ischemia; O | 2009 |
Aspirin therapy and primary prevention of cardiovascular disease in diabetes mellitus.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Female; Fibrinolytic Age | 2009 |
Use of aspirin among diabetics in the primary prevention of cardiovascular disease: need for reliable randomized evidence and astute clinical judgment.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Judgment; Male; Primary Prevent | 2009 |
Diabetes and the platelet: toward new therapeutic paradigms for diabetic atherothrombosis.
Topics: Acute Coronary Syndrome; Apoptosis; Aspirin; Blood Platelets; Clopidogrel; Diabetes Complications; D | 2010 |
A practical approach to the metabolic syndrome: review of current concepts and management.
Topics: Aspirin; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metabolic Syndro | 2010 |
Updated recommendations on daily aspirin use in patients with diabetes.
Topics: Aspirin; Coronary Disease; Cyclooxygenase Inhibitors; Diabetes Mellitus; Dose-Response Relationship, | 2010 |
Prevention of stroke following transient ischemic attack.
Topics: Anticoagulants; Antihypertensive Agents; Aspirin; Atrial Fibrillation; Brain; Carotid Stenosis; Clin | 2011 |
Effect of aspirin dose on mortality and cardiovascular events in people with diabetes: a meta-analysis.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors; Primar | 2011 |
Quality of care in diabetes: understanding the guidelines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Glucose; Clinical Trials as Topic; Diabetes | 2002 |
[Treatment of coronary insufficiency in diabetics: Part 2: acute coronary insufficiency].
Topics: Acute Disease; Adrenergic beta-Antagonists; Angina, Unstable; Angioplasty, Balloon, Coronary; Angiot | 1999 |
[Antiaggregation: aspirin].
Topics: Administration, Oral; Adult; Age Factors; Aged; Anticoagulants; Aspirin; Cardiovascular Diseases; Di | 2003 |
Current concepts of cardiovascular diseases in diabetes mellitus.
Topics: Aspirin; Cardiovascular Diseases; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus | 2003 |
[Primary and secondary prevention of coronary artery disease].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Aspir | 2003 |
The platelet in diabetes: focus on prevention of ischemic events.
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Humans; | 2003 |
Diabetes and chronic kidney disease: tragedy and challenge.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Blood Glucose; Calcium Channel Blocke | 2004 |
Prevention of cardiovascular disease: an evidence-based clinical aid 2004.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiova | 2004 |
Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Cohort Studie | 2004 |
Use of aspirin to reduce risks of cardiovascular disease in patients with diabetes: clinical and research challenges.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors | 2004 |
Comparative benefits of clopidogrel and aspirin in high-risk patient populations: lessons from the CAPRIE and CURE studies.
Topics: Angina, Unstable; Aspirin; Clopidogrel; Comorbidity; Diabetes Mellitus; Humans; Hypercholesterolemia | 2004 |
[Cardiovascular risk in diabetes--diagnostic and therapeutic aspects].
Topics: Abciximab; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Mon | 2004 |
Multidimensional pharmacologic strategies for diabetes.
Topics: Adult; Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspir | 2005 |
[Should we treat all diabetic patients with aspirin in primary prevention?].
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors; Primar | 2005 |
Exercise rehabilitation in heart disease: the real "polypill" for primary and secondary prevention.
Topics: Aspirin; Chronic Disease; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Exercise; | 2005 |
[Management of hypertension in patients with diabetes].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non | 2006 |
Stroke prevention in diabetes and obesity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atrial Fibrillation; Blood Glucose; Cardiovascular | 2006 |
Protection against glycation and similar post-translational modifications of proteins.
Topics: Aspirin; Carbohydrates; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; | 2006 |
[Coronary heart disease in patients with diabetes mellitus].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Biomarke | 2006 |
Antiplatelet therapy for primary prevention in diabetes.
Topics: Aspirin; Clinical Trials as Topic; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Diab | 2006 |
[Low-dose aspirin in patients with diabete melitus: risks and benefits regarding macro and microvascular complications].
Topics: Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Angiopathies | 2007 |
Independent predictors of stroke in patients with atrial fibrillation: a systematic review.
Topics: Age Factors; Aged; Aged, 80 and over; Aspirin; Atrial Fibrillation; Case-Control Studies; Cohort Stu | 2007 |
Quality indicators for the care of diabetes mellitus in vulnerable elders.
Topics: Aged; Aspirin; Diabetes Complications; Diabetes Mellitus; Evidence-Based Medicine; Frail Elderly; Gl | 2007 |
[Use of aspirin in diabetic patients].
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Male; Platelet Aggregation Inhi | 2007 |
The role of aspirin in cardiovascular prevention: implications of aspirin resistance.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Drug Resistance; Heart Failure; Humans; Hyperte | 2008 |
Chemistry, measurement, and clinical significance of platelet specific proteins.
Topics: Aspirin; Beta-Globulins; beta-Thromboglobulin; Blood Coagulation; Blood Coagulation Factors; Blood P | 1982 |
Platelets, prostaglandins and thrombotic disorders.
Topics: Arachidonic Acids; Arteriosclerosis; Aspirin; Blood Platelets; Calcium; Coronary Disease; Cyclic AMP | 1981 |
Studies on the biological balance between thromboxanes and prostacyclins in relation to the platelet-vessel wall interaction.
Topics: Adolescent; Adult; Aged; Aspirin; Bleeding Time; Blood Platelets; Blood Vessels; Child; Diabetes Mel | 1982 |
Prostaglandins, glucose homeostasis, and diabetes mellitus.
Topics: Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Blood Glucose; Diabetes Mellitus; Glucagon; Ho | 1983 |
Platelet function in diabetes mellitus.
Topics: Animals; Arteriosclerosis; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Diabetes Mellitus; D | 1980 |
[Arachidonic acid metabolism and platelet function in diabetics (author's transl)].
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Diabetes Mellitus; Epoprostenol; Humans; Imid | 1981 |
Prostaglandins and the alpha-cell.
Topics: Albuterol; Animals; Arginine; Aspirin; Blood Glucose; Diabetes Mellitus; Furosemide; Glucagon; Guine | 1981 |
Antiplatelet agents in the prevention of diabetic vascular complications.
Topics: Aspirin; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Hum | 1993 |
How can we best prolong life? Benefits of coronary risk factor reduction in non-diabetic and diabetic subjects.
Topics: Adult; Aspirin; Blood Pressure; Coronary Disease; Diabetes Mellitus; England; Humans; Hypercholester | 1993 |
Optimal management of chronic leg ulcers in the elderly.
Topics: Administration, Oral; Aged; Aging; Arterial Occlusive Diseases; Aspirin; Bandages; Combined Modality | 1997 |
Aspirin therapy in diabetes.
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Humans | 1997 |
[Intervention in risk factors and protection of target organs].
Topics: Alcohol Drinking; Aspirin; Cerebrovascular Disorders; Diabetes Complications; Diabetes Mellitus; Est | 1997 |
Risk factors for coronary heart disease in women.
Topics: Aged; Antioxidants; Aspirin; Cholesterol; Contraceptives, Oral; Coronary Disease; Diabetes Mellitus; | 1998 |
North of England evidence based guideline development project: guideline on the use of aspirin as secondary prophylaxis for vascular disease in primary care. North of England Aspirin Guideline Development Group.
Topics: Angina Pectoris; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Consumer Product Safet | 1998 |
Managing the diabetic patient with acute myocardial infarction.
Topics: Aspirin; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Humans; Myocardial Infarction; Ri | 1998 |
How to improve the cardiac prognosis for diabetes.
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitor | 1999 |
Diabetes and myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aspirin; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Huma | 1999 |
[Treatment of diabetic patients with ischaemic heart disease].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Diabetes Complicatio | 2000 |
Other drug treatments: the evidence.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspi | 2000 |
[Platelet aggregation inhibitors in diabetes mellitus].
Topics: Aspirin; Diabetes Mellitus; Diabetic Angiopathies; Humans; Platelet Aggregation; Platelet Aggregatio | 1999 |
Treatment for the procoagulant state in type 2 diabetes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Disorders; Blood Platelets; Diab | 2001 |
[Acetylsalicylic acid in primary prevention of cardiovascular events; literature study].
Topics: Aged; Aged, 80 and over; Arteriosclerosis; Aspirin; Diabetes Mellitus; Humans; Hyperlipidemias; Hype | 2002 |
Cardiovascular risk reduction in renal transplantation. Strategies for success.
Topics: Arteriosclerosis; Aspirin; Cardiovascular Agents; Cardiovascular Diseases; Comorbidity; Cost-Benefit | 2002 |
VA cooperative study on antiplatelet agents in diabetic patients after amputation for gangrene. IV. Issues in design, interpretation, and analysis.
Topics: Amputation, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; | 1986 |
Insulin and arachidonic acid metabolism in diabetes mellitus.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Aspirin; Blood Platelets; Diabe | 1985 |
62 trials available for aspirin and Diabetes Mellitus
Article | Year |
---|---|
Comparison of the Accuracy and Completeness of Records of Serious Vascular Events in Routinely Collected Data vs Clinical Trial-Adjudicated Direct Follow-up Data in the UK: Secondary Analysis of the ASCEND Randomized Clinical Trial.
Topics: Anticoagulants; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Fatty Acids, Omega-3; Female; H | 2021 |
Ticagrelor monotherapy after PCI in patients with concomitant diabetes mellitus and chronic kidney disease: TWILIGHT DM-CKD.
Topics: Aspirin; Diabetes Mellitus; Drug Therapy, Combination; Hemorrhage; Humans; Myocardial Infarction; Pe | 2022 |
Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial.
Topics: Aspirin; Cognition; Cognitive Dysfunction; Dementia; Diabetes Mellitus; Humans | 2022 |
Impact of diabetes mellitus on the pharmacodynamic effects of prasugrel and ticagrelor after switching from clopidogrel in patients with coronary artery disease.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Di | 2022 |
Rationale and design of the TUXEDO-2 India study: Ultra-Thin strUt Supraflex Cruz versus XiencE in a Diabetic pOpulation with multi-vessel disease-2.
Topics: Aspirin; Coronary Artery Disease; Diabetes Mellitus; Everolimus; Humans; Myocardial Infarction; Perc | 2023 |
Effect of low-dose aspirin on urinary 11-dehydro-thromboxane B2 in the ASCEND (A Study of Cardiovascular Events iN Diabetes) randomized controlled trial.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Thromboxane B2 | 2023 |
Aspirin vs Clopidogrel for Long-term Maintenance After Coronary Stenting in Patients With Diabetes: A Post Hoc Analysis of the HOST-EXAM Trial.
Topics: Aspirin; Clopidogrel; Diabetes Mellitus; Drug Therapy, Combination; Female; Hemorrhage; Humans; Male | 2023 |
Reliability of major bleeding events in UK routine data versus clinical trial adjudicated follow-up data.
Topics: Aspirin; Diabetes Mellitus; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Reproduc | 2023 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur | 2019 |
Proteinuria is independently associated with the incidence of primary cardiovascular events in diabetic patients.
Topics: Aged; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Female; Fibrinolytic Agents; Humans; Inci | 2020 |
Dabigatran Dual Therapy Versus Warfarin Triple Therapy Post-PCI in Patients With Atrial Fibrillation and Diabetes.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clopido | 2019 |
Role of Combination Antiplatelet and Anticoagulation Therapy in Diabetes Mellitus and Cardiovascular Disease: Insights From the COMPASS Trial.
Topics: Aged; Anticoagulants; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; Drug | 2020 |
Ticagrelor With or Without Aspirin in High-Risk Patients With Diabetes Mellitus Undergoing Percutaneous Coronary Intervention.
Topics: Aspirin; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Hemorrhage; Humans; Perc | 2020 |
ImpaCt of aspirin regimen on THrombin generation in diabEtic patients with acute coronary syndrome: CARTHaGE-ACS trial.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aspirin; Diabetes Mellitus; Drug Administra | 2021 |
Eligibility for Low-Dose Rivaroxaban Based on the COMPASS Trial: Insights from the Veterans Affairs Healthcare System.
Topics: Age Factors; Aged; Aged, 80 and over; Aspirin; Atherosclerosis; Budgets; Cardiovascular Diseases; Ci | 2021 |
Rivaroxaban and Aspirin in Patients With Symptomatic Lower Extremity Peripheral Artery Disease: A Subanalysis of the COMPASS Randomized Clinical Trial.
Topics: Aged; Amputation, Surgical; Aspirin; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus; Double | 2021 |
Current-Induced Vasodilation Specifically Detects, and Correlates With the Time Since, Last Aspirin Intake: An Interventional Study of 830 Patients.
Topics: Age Factors; Aged; Aged, 80 and over; Aspirin; Body Mass Index; Diabetes Mellitus; Female; Heart Dis | 2021 |
Impact of Comorbidities and Antiplatelet Regimen on Platelet Reactivity Levels in Patients Undergoing Transcatheter Aortic Valve Implantation.
Topics: Aged; Aged, 80 and over; Anemia; Aortic Valve Stenosis; Aspirin; Blood Platelets; Clopidogrel; Comor | 2021 |
Mortality Benefit of Rivaroxaban Plus Aspirin in Patients With Chronic Coronary or Peripheral Artery Disease.
Topics: Aged; Aspirin; Coronary Artery Disease; Diabetes Mellitus; Drug Therapy, Combination; Factor Xa Inhi | 2021 |
Dual antiplatelet therapy in patients with diabetes and acute coronary syndromes managed without revascularization.
Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Diabetes Mellitus; Dose-Response Relationship, | 2017 |
ASCEND: A Study of Cardiovascular Events iN Diabetes: Characteristics of a randomized trial of aspirin and of omega-3 fatty acid supplementation in 15,480 people with diabetes.
Topics: Aged; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug Ad | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus | 2018 |
Effects of n-3 Fatty Acid Supplements in Diabetes Mellitus.
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Dietary Su | 2018 |
Effects of n-3 Fatty Acid Supplements in Diabetes Mellitus.
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Dietary Su | 2018 |
Effects of n-3 Fatty Acid Supplements in Diabetes Mellitus.
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Dietary Su | 2018 |
Effects of n-3 Fatty Acid Supplements in Diabetes Mellitus.
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Dietary Su | 2018 |
A high glucose level is associated with decreased aspirin-mediated acetylation of platelet cyclooxygenase (COX)-1 at serine 529: A pilot study.
Topics: Acetylation; Adult; Aspirin; Blood Glucose; Blood Platelets; Cyclooxygenase 1; Diabetes Mellitus; Fe | 2019 |
Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in Elderly Japanese Patients with Atherosclerotic Risk Factors: Subanalysis of a Randomized Clinical Trial (JPPP-70).
Topics: Aged; Asian People; Aspirin; Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitus; Dyslipidem | 2019 |
Pharmacodynamic effects of EV-077 in patients with diabetes mellitus and coronary artery disease on aspirin or clopidogrel monotherapy: results of an in vitro pilot investigation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery D | 2014 |
The effect of dabigatran plasma concentrations and patient characteristics on the frequency of ischemic stroke and major bleeding in atrial fibrillation patients: the RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy).
Topics: Age Factors; Aged; Antithrombins; Aspirin; Atrial Fibrillation; Benzimidazoles; Dabigatran; Diabetes | 2014 |
The effect of dabigatran plasma concentrations and patient characteristics on the frequency of ischemic stroke and major bleeding in atrial fibrillation patients: the RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy).
Topics: Age Factors; Aged; Antithrombins; Aspirin; Atrial Fibrillation; Benzimidazoles; Dabigatran; Diabetes | 2014 |
The effect of dabigatran plasma concentrations and patient characteristics on the frequency of ischemic stroke and major bleeding in atrial fibrillation patients: the RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy).
Topics: Age Factors; Aged; Antithrombins; Aspirin; Atrial Fibrillation; Benzimidazoles; Dabigatran; Diabetes | 2014 |
The effect of dabigatran plasma concentrations and patient characteristics on the frequency of ischemic stroke and major bleeding in atrial fibrillation patients: the RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy).
Topics: Age Factors; Aged; Antithrombins; Aspirin; Atrial Fibrillation; Benzimidazoles; Dabigatran; Diabetes | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; D | 2014 |
Study design of the influence of SErotonin inhibition on patients with RENAl impairment or diabetes undergoing drug-eluting stent implantation (SERENADE) study: A multicenter, open-label, prospective, randomized study.
Topics: Aspirin; Clopidogrel; Coronary Angiography; Coronary Restenosis; Diabetes Mellitus; Drug Therapy, Co | 2015 |
Feasibility and impact of implementing a private care system's diabetes quality improvement intervention in the safety net: a cluster-randomized trial.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular Agents; C | 2015 |
Diabetes Mellitus and Prevention of Late Myocardial Infarction After Coronary Stenting in the Randomized Dual Antiplatelet Therapy Study.
Topics: Aged; Aspirin; Diabetes Mellitus; Drug Therapy, Combination; Drug-Eluting Stents; Female; Humans; Ma | 2016 |
Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.
Topics: Age Factors; Aged; Antineoplastic Agents, Phytogenic; Aspirin; Diabetes Mellitus; Drug-Eluting Stent | 2016 |
Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.
Topics: Age Factors; Aged; Antineoplastic Agents, Phytogenic; Aspirin; Diabetes Mellitus; Drug-Eluting Stent | 2016 |
Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.
Topics: Age Factors; Aged; Antineoplastic Agents, Phytogenic; Aspirin; Diabetes Mellitus; Drug-Eluting Stent | 2016 |
Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.
Topics: Age Factors; Aged; Antineoplastic Agents, Phytogenic; Aspirin; Diabetes Mellitus; Drug-Eluting Stent | 2016 |
Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.
Topics: Age Factors; Aged; Antineoplastic Agents, Phytogenic; Aspirin; Diabetes Mellitus; Drug-Eluting Stent | 2016 |
Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.
Topics: Age Factors; Aged; Antineoplastic Agents, Phytogenic; Aspirin; Diabetes Mellitus; Drug-Eluting Stent | 2016 |
Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.
Topics: Age Factors; Aged; Antineoplastic Agents, Phytogenic; Aspirin; Diabetes Mellitus; Drug-Eluting Stent | 2016 |
Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.
Topics: Age Factors; Aged; Antineoplastic Agents, Phytogenic; Aspirin; Diabetes Mellitus; Drug-Eluting Stent | 2016 |
Development and Validation of a Prediction Rule for Benefit and Harm of Dual Antiplatelet Therapy Beyond 1 Year After Percutaneous Coronary Intervention.
Topics: Age Factors; Aged; Antineoplastic Agents, Phytogenic; Aspirin; Diabetes Mellitus; Drug-Eluting Stent | 2016 |
Aspirin for Stroke Prevention in Elderly Patients With Vascular Risk Factors: Japanese Primary Prevention Project.
Topics: Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Comorbidity; Diabetes Mellitus; Dyslipidemias; Fem | 2016 |
Cost-effective recruitment methods for a large randomised trial in people with diabetes: A Study of Cardiovascular Events iN Diabetes (ASCEND).
Topics: Aspirin; Cardiovascular Diseases; Consent Forms; Cost-Benefit Analysis; Diabetes Mellitus; Dietary S | 2016 |
Randomized Angiographic and Intravascular Ultrasound Comparison of Dual-Antiplatelet Therapy vs Triple-Antiplatelet Therapy to Reduce Neointimal Tissue Proliferation in Diabetic Patients.
Topics: Aspirin; Cilostazol; Clopidogrel; Comorbidity; Coronary Angiography; Coronary Artery Disease; Corona | 2017 |
Rationale, design, and baseline data of the Japanese Primary Prevention Project (JPPP)-a randomized, open-label, controlled trial of aspirin versus no aspirin in patients with multiple risk factors for vascular events.
Topics: Aged; Aged, 80 and over; Asian People; Aspirin; Cohort Studies; Diabetes Mellitus; Dose-Response Rel | 2010 |
Antiplatelet effect of once- or twice-daily aspirin dosage in stable coronary artery disease patients with diabetes.
Topics: Adult; Aged; Aspirin; Blood Platelets; Chemoprevention; Coronary Artery Disease; Diabetes Mellitus; | 2010 |
Impact of adjunctive cilostazol therapy on platelet function profiles in patients with and without diabetes mellitus on aspirin and clopidogrel therapy.
Topics: Aged; Aspirin; Blood Platelets; Chemotherapy, Adjuvant; Cilostazol; Clopidogrel; Cross-Over Studies; | 2011 |
Comparison of the effect of cilostazol with aspirin on circulating endothelial progenitor cells and small-dense LDL cholesterol in diabetic patients with cerebral ischemia: a randomized controlled pilot trial.
Topics: Aged; Aspirin; Brain Ischemia; Cholesterol, LDL; Cilostazol; Diabetes Mellitus; Endothelium, Vascula | 2011 |
Genetic determinants of platelet reactivity during acetylsalicylic acid therapy in diabetic patients: evaluation of 27 polymorphisms within candidate genes.
Topics: Aged; Aspirin; Blood Platelets; Diabetes Mellitus; Female; Genotype; Humans; Male; Middle Aged; Muta | 2011 |
Pioglitazone inhibits platelet function and potentiates the effects of aspirin: a prospective observation study.
Topics: Aspirin; Blood Platelets; Case-Control Studies; Diabetes Mellitus; Drug Synergism; Female; Humans; H | 2012 |
Clinical features and racial/ethnic differences among the 3020 participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial.
Topics: Aged; Antihypertensive Agents; Aspirin; Black or African American; Blood Pressure; Chi-Square Distri | 2013 |
Cardiovascular therapy, diagnostic procedures, and control of risk factors in patients with diabetes or coronary artery disease in Poland: the Kardia‑Pol registry.
Topics: Aged; Aged, 80 and over; Aspirin; Comorbidity; Coronary Artery Disease; Diabetes Mellitus; Female; H | 2012 |
Randomized controlled trial of symptomatic middle cerebral artery stenosis: endovascular versus medical therapy in a Chinese population.
Topics: Adult; Aged; Angioplasty; Asian People; Aspirin; Clopidogrel; Diabetes Mellitus; Drug Therapy, Combi | 2012 |
Assessment of the Siksika chronic disease nephropathy-prevention clinic.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Bl | 2013 |
Amplified benefit of clopidogrel versus aspirin in patients with diabetes mellitus.
Topics: Aged; Aspirin; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Endpoi | 2002 |
Effectiveness of clopidogrel versus aspirin in preventing acute myocardial infarction in patients with symptomatic atherothrombosis (CAPRIE trial).
Topics: Age Factors; Aged; Aspirin; Clopidogrel; Creatinine; Diabetes Mellitus; Female; Humans; Male; Massac | 2002 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Topics: Aged; Anticoagulants; Aspirin; Catheterization; Clopidogrel; Combined Modality Therapy; Comorbidity; | 2004 |
Patient-directed intervention versus clinician reminders alone to improve aspirin use in diabetes: a cluster randomized trial.
Topics: Aged; Aspirin; Diabetes Mellitus; Evidence-Based Medicine; Female; Humans; Interviews as Topic; Male | 2008 |
Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Im
Topics: Aged; Aspirin; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Artery Disease; Coronary Rest | 2008 |
Blockade of chlorpropamide alcohol flush by aspirin.
Topics: Aspirin; Blood Vessels; Body Temperature; Chlorpheniramine; Chlorpropamide; Cimetidine; Diabetes Mel | 1980 |
Study to begin on whether aspirin can delay senile cataract formation.
Topics: Aged; Aspirin; Cataract; Clinical Trials as Topic; Diabetes Mellitus; Dose-Response Relationship, Dr | 1980 |
The Hypertension Optimal Treatment (HOT) Study--patient characteristics: randomization, risk profiles, and early blood pressure results.
Topics: Adrenergic beta-Antagonists; Age Distribution; Aged; Aged, 80 and over; Angiotensin-Converting Enzym | 1994 |
C-peptide and the classification of diabetes mellitus patients in the Early Treatment Diabetic Retinopathy Study. Report number 6. The ETDRS Research Group.
Topics: Adult; Aspirin; C-Peptide; Combined Modality Therapy; Diabetes Mellitus; Diabetic Retinopathy; Discr | 1993 |
Association of elevated serum lipid levels with retinal hard exudate in diabetic retinopathy. Early Treatment Diabetic Retinopathy Study (ETDRS) Report 22.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Blood-Retinal Barrier; Capillary Permeability; Diabetes Co | 1996 |
Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Arteriosclerosis; Aspirin; beta Carotene; Body Mass In | 1998 |
Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Arteriosclerosis; Aspirin; beta Carotene; Body Mass In | 1998 |
Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Arteriosclerosis; Aspirin; beta Carotene; Body Mass In | 1998 |
Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Arteriosclerosis; Aspirin; beta Carotene; Body Mass In | 1998 |
Stroke in patients with acute coronary syndromes: incidence and outcomes in the platelet glycoprotein IIb/IIIa in unstable angina. Receptor suppression using integrilin therapy (PURSUIT) trial. The PURSUIT Investigators.
Topics: Acute Disease; Age Factors; Aged; Angina, Unstable; Aspirin; Brain Damage, Chronic; Cerebral Hemorrh | 1999 |
Alcohol consumption and risk of coronary heart disease by diabetes status.
Topics: Alcohol Drinking; Aspirin; beta Carotene; Cardiovascular Diseases; Coronary Disease; Diabetes Mellit | 2000 |
Aspirin stimulates insulin and glucagon secretion and increases glucose tolerance in normal and diabetic subjects.
Topics: Adult; Aged; Aspirin; Blood Glucose; Diabetes Mellitus; Glucagon; Glucose; Humans; Ibuprofen; Insuli | 1978 |
Aspirin effects on mortality and morbidity in patients with diabetes mellitus. Early Treatment Diabetic Retinopathy Study report 14. ETDRS Investigators.
Topics: Adolescent; Adult; Aged; Aspirin; Cerebrovascular Disorders; Diabetes Mellitus; Diabetic Retinopathy | 1992 |
European stroke prevention study: effectiveness of antiplatelet therapy in diabetic patients in secondary prevention of stroke.
Topics: Aged; Aspirin; Cerebrovascular Disorders; Diabetes Complications; Diabetes Mellitus; Dipyridamole; D | 1992 |
VA cooperative study on antiplatelet agents in diabetic patients after amputation for gangrene. IV. Issues in design, interpretation, and analysis.
Topics: Amputation, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; | 1986 |
291 other studies available for aspirin and Diabetes Mellitus
Article | Year |
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Synthesis and biological evaluation of sulfonylurea and thiourea derivatives substituted with benzenesulfonamide groups as potential hypoglycemic agents.
Topics: Adipocytes; Animals; Benzenesulfonamides; Biological Transport; Chemistry, Pharmaceutical; Diabetes | 2009 |
Use of aspirin for primary prevention in patients with diabetes during the COVID-19 pandemic.
Topics: Aspirin; Cardiovascular Diseases; COVID-19; Diabetes Mellitus; Humans; Pandemics; Platelet Aggregati | 2022 |
The comparison between the effects of aspirin and clopidogrel monotherapy on postoperative bleeding in diabetic patients after off-pump coronary artery bypass surgery.
Topics: Aspirin; Clopidogrel; Coronary Artery Bypass, Off-Pump; Diabetes Mellitus; Humans; Platelet Aggregat | 2021 |
Application of Age, Body Mass Index, Chronic Kidney Disease, Diabetes, and Genotyping Score for Efficacy of Clopidogrel: Secondary Analysis of the CHANCE Trial.
Topics: Age Factors; Aged; Aspirin; Body Mass Index; Cerebrovascular Disorders; Clopidogrel; Cytochrome P-45 | 2022 |
Associations between aspirin prophylaxis and fetal growth and preeclampsia in women with pregestational diabetes.
Topics: Analgesics; Aspirin; Diabetes Mellitus; Female; Fetal Development; Humans; Pre-Eclampsia; Pregnancy; | 2022 |
Association Between Platelet Reactivity and Long-Term Bleeding Complications After Percutaneous Coronary Intervention According to Diabetes Status.
Topics: Aspirin; Clopidogrel; Diabetes Mellitus; Hemorrhage; Humans; Percutaneous Coronary Intervention; Pla | 2022 |
The end of aspirin for dementia prevention in diabetes?
Topics: Aspirin; Cardiovascular Diseases; Cognition; Dementia; Diabetes Mellitus; Humans; Platelet Aggregati | 2022 |
Trends and Determinants of Self-reported Aspirin Use Among Patients With Diabetes Stratified by Presence and Risk of Cardiovascular Diseases: A Repeated Pan-Canadian Cross-sectional Study.
Topics: Aspirin; Canada; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus; Humans; Platel | 2022 |
The Association between Glycosylated Hemoglobin Level and Platelets Reactivity in Patients with Diabetes Mellitus Undergoing Elective Coronary Artery Bypass Grafting.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Coronary Artery Bypass; Diabetes Mellitus; Glycated | 2023 |
Association between first-step analgesic use and cancer in patients with diabetes.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Female; Humans; Mal | 2023 |
Association between first-step analgesic use and cancer in patients with diabetes.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Female; Humans; Mal | 2023 |
Association between first-step analgesic use and cancer in patients with diabetes.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Female; Humans; Mal | 2023 |
Association between first-step analgesic use and cancer in patients with diabetes.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Female; Humans; Mal | 2023 |
Association between first-step analgesic use and cancer in patients with diabetes.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Female; Humans; Mal | 2023 |
Association between first-step analgesic use and cancer in patients with diabetes.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Female; Humans; Mal | 2023 |
Association between first-step analgesic use and cancer in patients with diabetes.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Female; Humans; Mal | 2023 |
Association between first-step analgesic use and cancer in patients with diabetes.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Female; Humans; Mal | 2023 |
Association between first-step analgesic use and cancer in patients with diabetes.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Female; Humans; Mal | 2023 |
Aspirin Suppresses Hepatic Glucagon Signaling Through Decreasing Production of Thromboxane A2.
Topics: Aspirin; Diabetes Mellitus; Glucagon; Gluconeogenesis; Glucose; Humans; Hyperglycemia; Hypoglycemic | 2023 |
Aspirin and Risk of Specific Breast Cancer Subtype in Women with Diabetes.
Topics: Aspirin; Breast Neoplasms; Diabetes Mellitus; Female; Hormones; Humans; Middle Aged; Retrospective S | 2023 |
Aspirin in diabetic patients at primary prevention: insights of the VITAL cohort.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Hypertension; Male; Retrospective Studi | 2023 |
Hypertensive disorders of pregnancy pre- and postaspirin guideline publication in individuals with pregestational diabetes mellitus.
Topics: Aspirin; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hypertension, Pregnancy-Induced | 2023 |
Temporal trends in low-dose aspirin therapy for primary prevention of cardiovascular disease in European adults with and without diabetes.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Europe; Female; | 2023 |
Low-dose aspirin therapy for primary prevention of cardiovascular disease: where are we at?
Topics: Adult; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors; | 2023 |
Prediabetes, diabetes and loss of disability-free survival in a community-based older cohort: a post-hoc analysis of the ASPirin in Reducing Events in the Elderly trial.
Topics: Aged; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Prediabetic State; Prognosis | 2023 |
The Diabetic Platelets.
Topics: Aspirin; Blood Platelets; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose; Humans; Platelet Ag | 2023 |
Mortality in Patients Hospitalized With Acute Myocardial Infarction Without Standard Modifiable Risk Factors: The ARIC Study Community Surveillance.
Topics: Aspirin; Diabetes Mellitus; Hospitalization; Humans; Myocardial Infarction; Prognosis; Risk Factors | 2023 |
Association of low-dose aspirin use for primary prevention with self-reported kidney stones prevalence: a cross-sectional study.
Topics: Adult; Aged; Aspirin; Cross-Sectional Studies; Diabetes Mellitus; Humans; Hypertension; Kidney Calcu | 2023 |
Risks May Outweigh Benefits Of Aspirin Use in Diabetes.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors; Risk F | 2019 |
Metformin use and risk of gastric adenocarcinoma in a Swedish population-based cohort study.
Topics: Adenocarcinoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Fe | 2019 |
The 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: New features and the ‘Ten Commandments’ of the 2019 Guidelines are discussed by Professor Peter J. Grant and Professor Francesco Cosen
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Blood Pressure; Cardiovascular Diseases; Cholesterol, | 2019 |
Interaction Between Diabetes Mellitus and Platelet Reactivity in Determining Long-Term Outcomes Following Percutaneous Coronary Intervention.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Diabetes Mellitus; Drug Re | 2020 |
Gender Differences in Platelet Reactivity in Diabetic Patients Receiving Dual Antiplatelet Therapy.
Topics: Adenosine; Aftercare; Aspirin; Blood Platelets; Diabetes Mellitus; Drug Therapy, Combination; Female | 2020 |
Aspirin for primary prevention of cardiovascular disease in women.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Female; Hemorrh | 2020 |
Twilight, the Dawn of a New Era of Aspirin-Free PCI?
Topics: Aspirin; Diabetes Mellitus; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibit | 2020 |
Cost-utility of ticagrelor plus aspirin in diabetic patients with stable coronary artery disease.
Topics: Aspirin; Brain Ischemia; Coronary Artery Disease; Diabetes Mellitus; Humans; Percutaneous Coronary I | 2021 |
Potential drug-drug interactions in ICU patients: a retrospective study.
Topics: Aspirin; Diabetes Mellitus; Drug Interactions; Enoxaparin; Hospitalization; Humans; Hypertension; In | 2020 |
Comparison of the effects of cilostazol and aspirin on wound healing in patients with diabetic foot ulcer and peripheral artery disease.
Topics: Aspirin; Cilostazol; Diabetes Mellitus; Diabetic Foot; Humans; Peripheral Arterial Disease; Retrospe | 2020 |
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Topics: Aspirin; Diabetes Mellitus; Humans; Percutaneous Coronary Intervention; Purinergic P2Y Receptor Anta | 2020 |
Reply: P2Y
Topics: Aspirin; Diabetes Mellitus; Humans; Percutaneous Coronary Intervention; Purinergic P2Y Receptor Anta | 2020 |
The Associations of Aspirin, Statins, and Metformin With Lung Cancer Risk and Related Mortality: A Time-Dependent Analysis of Population-Based Nationally Representative Data.
Topics: Aspirin; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung Neoplasms; | 2021 |
Co-morbid risk factors and NSAID use among white and black Americans that predicts overall survival from diagnosed colon cancer.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Black or African American; Cohort Studies; | 2020 |
The impact of patient-centered medical home certification on quality of care for patients with diabetes.
Topics: Age Factors; Aged; Aspirin; Blood Pressure; Certification; Cholesterol; Diabetes Mellitus; Electroni | 2021 |
Benefits and Risks of Prolonged Duration Dual Antiplatelet Therapy (Clopidogrel and Aspirin) After Percutaneous Coronary Intervention in High-Risk Patients With Diabetes Mellitus.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus; Dual | 2021 |
Impact of Preoperative Aspirin on Long-Term Outcomes in Diabetic Patients Following Coronary Artery Bypass Grafting: a Propensity Score Matched Study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Artery Bypass; Coronary Artery Disease; D | 2020 |
The use of aspirin for primary prevention of cardiovascular disease is associated with a lower likelihood of COVID-19 infection.
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; COVID-19; COVID-19 Drug Treatment; Diabetes Mellitus; | 2021 |
Aspirin and pre-eclampsia prevention in women with pre-existing diabetes: a retrospective study.
Topics: Aspirin; Diabetes Mellitus; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Retrospective Studie | 2021 |
Outcomes of Individuals With and Without Heart Failure Presenting With Acute Coronary Syndrome.
Topics: Acute Coronary Syndrome; Aged; Angina, Unstable; Aspirin; Case-Control Studies; Clopidogrel; Diabete | 2021 |
Decreased in-hospital mortality associated with aspirin administration in hospitalized patients due to severe COVID-19.
Topics: Adenosine Monophosphate; Adult; Aged; Alanine; Antiviral Agents; Aspirin; Blood Platelets; Coronary | 2021 |
Benefits of Ticagrelor Plus Aspirin According to Diabetes-Related Factors: A Complex Equation.
Topics: Aspirin; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagon | 2021 |
Statin but not aspirin treatment is associated with reduced cardiovascular risk in patients with diabetes without obstructive coronary artery disease: a cohort study from the Western Denmark Heart Registry.
Topics: Aspirin; Brain Ischemia; Cardiovascular Diseases; Cohort Studies; Coronary Artery Disease; Denmark; | 2022 |
Long-term continuous use of proton-pump inhibitors is associated with renal function decline in patients without acute kidney injury.
Topics: Acute Kidney Injury; Aged; Angiotensin Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal | 2021 |
Daily Low-Dose Aspirin, Diabetes, and Age-Still Looking for a Balance.
Topics: Aspirin; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors | 2021 |
Treatment Outcomes of Clopidogrel in Patients With ACS and Diabetes Undergoing PCI-Analysis of Beijing Municipal Medical Insurance Database.
Topics: Acute Coronary Syndrome; Angina, Unstable; Aspirin; Beijing; Clopidogrel; Databases, Factual; Diabet | 2021 |
Incidence, Patterns, and Associations Between Dual-Antiplatelet Therapy Cessation and Risk for Adverse Events Among Patients With and Without Diabetes Mellitus Receiving Drug-Eluting Stents: Results From the PARIS Registry.
Topics: Aged; Aspirin; Coronary Artery Disease; Coronary Thrombosis; Diabetes Mellitus; Drug Administration | 2017 |
Recommendations on the Clinical Use of Compound Danshen Dripping Pills.
Topics: Angina Pectoris; Aspirin; Camphanes; Clopidogrel; Coronary Disease; Diabetes Mellitus; Diabetic Neph | 2017 |
Prevention of Cardiovascular Events in Patients With Diabetes: How Beneficial Is Dual Antiplatelet Therapy?
Topics: Aspirin; Belgium; Clopidogrel; Diabetes Mellitus; Drug Therapy, Combination; Humans; Myocardial Infa | 2017 |
Low-Dose Aspirin Reduces Breast Cancer Risk in Women with Diabetes: A Nationwide Retrospective Cohort Study in Taiwan.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Breast Neoplasms; Cardiovascular Dise | 2017 |
Patients With Diabetes Without Significant Angiographic Coronary Artery Disease Have the Same Risk of Myocardial Infarction as Patients Without Diabetes in a Real-World Population Receiving Appropriate Prophylactic Treatment.
Topics: Aged; Aspirin; Cohort Studies; Comorbidity; Coronary Angiography; Coronary Artery Disease; Denmark; | 2017 |
Relevance of Indications for CABG in Evaluating the Effect of Dual Antiplatelet Therapy.
Topics: Aspirin; Coronary Artery Bypass; Diabetes Mellitus; Freedom; Humans; Platelet Aggregation Inhibitors | 2017 |
MMP-2, MMP-9, and TIMP-4 and Response to Aspirin in Diabetic and Nondiabetic Patients with Stable Coronary Artery Disease: A Pilot Study.
Topics: Aspirin; Blood Platelets; Coronary Artery Disease; Diabetes Mellitus; Female; Humans; Male; Matrix M | 2017 |
Associations of Statins and Diabetes with Diagnosis of Ulcerated Cutaneous Melanoma.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Sectio | 2017 |
Does Aspirin Decrease Risk of Specific Breast Cancer Subtype in Women with Diabetes?
Topics: Aspirin; Breast Neoplasms; Diabetes Mellitus; Female; Humans; Risk; Risk Factors | 2017 |
False increase of glycated hemoglobin due to aspirin interference in Tosoh G8 analyzer.
Topics: Aspirin; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus; False Positive Reac | 2018 |
Cardiovascular Disease and Risk Management: Review of the American Diabetes Association Standards of Medical Care in Diabetes 2018.
Topics: Adult; Antihypertensive Agents; Aspirin; Blood Pressure Monitoring, Ambulatory; Coronary Disease; Di | 2018 |
Aspirin for primary prevention of CVD: a matter of balance.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Primary Prevention | 2018 |
Primary vascular prevention: The end of the road for aspirin?
Topics: Aspirin; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Angiopathies; Evidence-Based Medicine | 2018 |
Aspirin for primary prevention of cardiovascular disease events in diabetes: the balancing act?
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Primary Prevention | 2018 |
In diabetes with no CVD, aspirin reduced serious vascular events but increased major bleeding at 7.4 years.
Topics: Aspirin; Diabetes Mellitus; Hemorrhage; Humans; Primary Prevention | 2018 |
Aspirin for primary prevention of cardiovascular disease in diabetes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans | 2019 |
What have we learned about using aspirin for primary prevention from the ASCEND and ARRIVE trials?
Topics: Aspirin; Cardiovascular Agents; Cardiovascular Diseases; Clinical Decision-Making; Diabetes Mellitus | 2019 |
Aspirin in people with diabetes: Time to clean up the prescription list?
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Primary Prevention; Risk Assessment | 2019 |
Association of Long-term Use of Low-Dose Aspirin as Chemoprevention With Risk of Lung Cancer.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Dis | 2019 |
Aspirin Use for Cardiovascular Disease Prevention in an African American Population: Prevalence and Associations with Health Behavior Beliefs.
Topics: Aged; Aspirin; Black or African American; Cardiovascular Diseases; Diabetes Mellitus; Female; Health | 2019 |
A precision medicine approach for the primary prevention of cardiovascular events in diabetic patients.
Topics: Aspirin; Cardiovascular Diseases; Cardiovascular System; Diabetes Mellitus; Humans; Precision Medici | 2019 |
Do Statins Have a Positive Impact on Patients with Coronary Microvascular Dysfunction on Long-Term Clinical Outcome? A Large Retrospective Cohort Study.
Topics: Aged; Aspirin; Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus; Drug-Related Side E | 2019 |
Influence of blood pressure on the effects of low-dose asprin in elderly patients with multiple atherosclerotic risks.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Pressure; Diabetes Mellitus; Dyslipidemias; Female; Hemorrha | 2019 |
Impact of aging on platelet reactivity in diabetic patients receiving dual antiplatelet therapy.
Topics: Acute Coronary Syndrome; Age Factors; Aged; Aged, 80 and over; Aging; Aspirin; Clopidogrel; Diabetes | 2019 |
Secondary prevention advices after cardiovascular index event: From drug prescription to risk factors control in real world practice.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Blood Pressure; Cardiovascular Diseases; | 2019 |
Collagen-Induced Platelet Aggregates, Diabetes, and Aspirin Therapy Predict Clinical Outcomes in Acute Ischemic Stroke.
Topics: Aged; Aged, 80 and over; Aspirin; Biomarkers; Blood Platelets; Brain Ischemia; Comorbidity; Cross-Se | 2019 |
Vitamin D levels and platelet reactivity in diabetic patients receiving dual antiplatelet therapy.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Aspirin; Biomarkers; Clopidogrel; Diabetes Mellitu | 2019 |
Challenging the FDA black box warning for high aspirin dose with ticagrelor in patients with diabetes.
Topics: Adenosine; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Abnormalities; Diabetes | 2013 |
Evidenced-based antithrombotic therapy for acute coronary syndromes.
Topics: Adenosine; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Drug Labeling; Human | 2013 |
Relation between time of symptom onset of ST-segment elevation myocardial infarction and patient baseline characteristics: from the National Cardiovascular Data Registry.
Topics: Adrenergic beta-Antagonists; Age Distribution; Aged; Angiotensin Receptor Antagonists; Aspirin; Card | 2013 |
Intracranial hemorrhages related with warfarin use and comparison of warfarin and acetylsalicylic acid.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Coagulation; | 2014 |
Primary non-variceal upper gastrointestinal bleeding in NSAID and low-dose aspirin users: development and validation of risk scores for either medication in two large Dutch cohorts.
Topics: Adolescent; Adult; Age Factors; Aged; Anemia; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulant | 2014 |
Antihyperglycemic and antinociceptive activity evaluation of 'khoyer' prepared from boiling the wood of Acacia catechu in water.
Topics: Acacia; Acetic Acid; Analgesics; Animals; Aspirin; Bangladesh; Behavior, Animal; Blood Glucose; Diab | 2013 |
Low-dose aspirin-associated upper gastric and duodenal ulcers in Japanese patients with no previous history of peptic ulcers.
Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; Asian People; Aspirin; Diabetes Complications; Diabetes | 2013 |
Decade-long trends in the characteristics, management and hospital outcomes of diabetic patients with ST-segment elevation myocardial infarction.
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Angiotensin Receptor Antagonists; Angiotensin-Conver | 2014 |
Low-dose aspirin for prevention of cardiovascular disease in patients with chronic kidney disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aspirin; Atherosclerosis; Cardiovascular Diseases; Diabete | 2014 |
[The clinical analysis of atrial fibrillation of 1 310 in patients in Urumqi of China].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Atrial Fibrillation; China; Comor | 2014 |
Age-related prevalence of diabetes mellitus, cardiovascular disease and anticoagulation therapy use in a urolithiasis population and their effect on outcomes: the Clinical Research Office of the Endourological Society Ureteroscopy Global Study.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cardiovascula | 2015 |
Can aspirin reduce the risk of colorectal cancer in people with diabetes? A population-based cohort study.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Colorectal Neoplasms; | 2015 |
Assessing Diabetes Care Disparities with Ambulatory Care Quality Measures.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Aspirin; Cholesterol, LDL; Diabetes Mellitus; Electronic H | 2015 |
Association between low-dose aspirin and periodontal disease: results from the continuous national health and nutrition examination survey (NHANES) 2011-2012.
Topics: Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Sectional Studies; Diabe | 2015 |
Aspirin Has a Protective Effect Against Adverse Outcomes in Patients with Nonvariceal Upper Gastrointestinal Bleeding.
Topics: Adult; Aged; Aging; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Female; Fibrinolytic Agents | 2015 |
Risk factor burden and control at the time of admission in patients with acute myocardial infarction: Results from the NCDR.
Topics: Aged; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Dyslipidemias; Female; Guideline Adherenc | 2015 |
Are metformin, statin and aspirin use still associated with overall mortality among colorectal cancer patients with diabetes if adjusted for one another?
Topics: Aged; Aged, 80 and over; Aspirin; Colorectal Neoplasms; Diabetes Complications; Diabetes Mellitus; F | 2015 |
Clopidogrel response variability is associated with endothelial dysfunction in coronary artery disease patients receiving dual antiplatelet therapy.
Topics: Activation, Metabolic; Aged; Aspirin; Brachial Artery; Clopidogrel; Coronary Disease; Cytochrome P-4 | 2015 |
Influence of Diabetes Mellitus and Cigarette Smoking on Variability of the Clopidogrel-Induced Antiplatelet Effect and Efficacy of Active Management of the Target P2Y12 Reaction Unit Range in Patients Undergoing Neurointerventional Procedures.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Carotid Stenosis; Cilostazol; Clopidogrel; Dia | 2016 |
Aspirin Use for the Primary Prevention of Myocardial Infarction Among Men in North Carolina, 2013.
Topics: Aged; Aspirin; Behavioral Risk Factor Surveillance System; Diabetes Mellitus; Humans; Hypercholester | 2015 |
Aspirin in the prevention of cardiovascular events in patients with diabetes.
Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Diabetes Complications; Diabetes Mellitus; Drug Admin | 2016 |
Impact of diabetes on immature platelets fraction and its relationship with platelet reactivity in patients receiving dual antiplatelet therapy.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Clopidogrel; Diabetes Mellitus; Drug Therapy, Combinati | 2016 |
Prevalence and Prognosis of High-risk Myocardial Infarction Patient Candidates to Extended Antiplatelet Therapy.
Topics: Adenosine; Age Factors; Aged; Aged, 80 and over; Aspirin; Diabetes Mellitus; Drug Therapy, Combinati | 2016 |
Coronary Thrombosis and Major Bleeding After PCI With Drug-Eluting Stents: Risk Scores From PARIS.
Topics: Acute Coronary Syndrome; Age Factors; Aged; Anemia; Aspirin; Body Mass Index; Clopidogrel; Cohort St | 2016 |
Diabetes mellitus, glucose control parameters and platelet reactivity in ticagrelor treated patients.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Blood Glucose; Blood Platelets; Diabetes Complica | 2016 |
Topics: Aspirin; Atherosclerosis; Brazil; Cardiovascular Diseases; Coronary Artery Disease; Diabetes Mellitu | 2014 |
Association of Low-Dose Aspirin and Survival of Women With Endometrial Cancer.
Topics: Adenocarcinoma; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Comorbidity; Diabetes Mellit | 2016 |
Effects of low-dose aspirin in subjects with dyslipidemia.
Topics: Adult; Aspirin; C-Reactive Protein; Cholesterol, LDL; Convalescence; Coronary Angiography; Coronary | 2016 |
Evaluation of potential drug- drug interactions among Palestinian hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Arabs; Aspirin; Calcium Carbonate; Comorbidity; Diabetes | 2016 |
Combined aspirin and anticoagulant therapy in patients with atrial fibrillation.
Topics: Academic Medical Centers; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Coronary Artery Diseas | 2017 |
In vitro glycation of bovine liver catalase by glucose and fructose and antigycation effects of aspirin: a spectroscopic study.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catalase; Cattle; Diabetes Mellitus; Fruc | 2017 |
Aspirin for Primary Cardiovascular Risk Prevention and Beyond in Diabetes Mellitus.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Risk Factors | 2016 |
Decade-Long Trends (2001 to 2011) in the Use of Evidence-Based Medical Therapies at the Time of Hospital Discharge for Patients Surviving Acute Myocardial Infarction.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme I | 2016 |
Optimal duration of dual antiplatelet therapy after stent implantation in patients with or without diabetes.
Topics: Aspirin; Diabetes Mellitus; Drug Therapy, Combination; Drug-Eluting Stents; Humans; Platelet Aggrega | 2016 |
Review: In adults with diabetes, aspirin does not prevent CV events compared with placebo.
Topics: Adult; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors | 2016 |
Bleeding risk following percutaneous coronary intervention in patients with diabetes prescribed dual anti-platelet therapy.
Topics: Aged; Aspirin; Comorbidity; Coronary Artery Disease; Diabetes Mellitus; Drug Therapy, Combination; D | 2016 |
Adding CABG to the Dual Antiplatelet Salad.
Topics: Aspirin; Coronary Artery Bypass; Diabetes Mellitus; Freedom; Humans; Platelet Aggregation Inhibitors | 2017 |
Long-Term Comparative Outcomes of Patients With Peripheral Artery Disease With and Without Concomitant Coronary Artery Disease.
Topics: Adrenergic beta-Antagonists; Aged; Aspirin; California; Coronary Artery Disease; Diabetes Mellitus; | 2017 |
Baseline platelet activity and response after clopidogrel in 257 diabetics among 822 patients with coronary artery disease.
Topics: Aged; Aspirin; Baltimore; Biomarkers; Clopidogrel; Coronary Artery Disease; Diabetes Mellitus; Femal | 2008 |
Biochemical evaluation of the antiplatelet effect of aspirin in patients at different levels of cardiovascular risk.
Topics: Aged; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Female | 2008 |
Primary prevention of cardiovascular events in diabetes: is there a role for aspirin?
Topics: Antioxidants; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Humans; Pe | 2009 |
[Factors that influence the implementation of the guidelines for aspirin use by diabetic patients in Israel].
Topics: Adult; Aspirin; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Female; Guidelines | 2008 |
Patient characteristics associated with the choice of triple antithrombotic therapy in acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aged; Anemia; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Atri | 2009 |
Platelet-bound P-selectin expression in patients with coronary artery disease: impact on clinical presentation and myocardial necrosis, and effect of diabetes mellitus and anti-platelet medication.
Topics: Acute Coronary Syndrome; Angina Pectoris; Aspirin; Biomarkers; Blood Platelets; Clopidogrel; Coronar | 2010 |
[Diabetes and a low dose of aspirin].
Topics: Aspirin; Diabetes Mellitus; Diabetic Angiopathies; Humans | 2009 |
Another look at the results of the JUPITER trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Body Mass Index; C-Reactive Prot | 2009 |
Impact of chronic antithrombotic therapy on hospital course of patients with acute myocardial infarction.
Topics: Age Factors; Aged; Anticoagulants; Aspirin; Bundle-Branch Block; Coumarins; Diabetes Mellitus; Femal | 2009 |
Long-term effectiveness and safety of sirolimus stent implantation for coronary in-stent restenosis results of the TRUE (Tuscany Registry of sirolimus for unselected in-stent restenosis) registry at 4 years.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Agents; Clopidogrel; Coronary Restenosis; Coronary | 2010 |
Impact of chronic kidney disease on platelet function profiles in diabetes mellitus patients with coronary artery disease taking dual antiplatelet therapy.
Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Cross-Sectional Studies; Diabe | 2010 |
[Evaluation and improvement in the prescribing of anti-platelet drugs in diabetic patients].
Topics: Adult; Aspirin; Diabetes Mellitus; Drug Prescriptions; Female; Humans; Male; Platelet Aggregation In | 2011 |
Aspirin for primary prevention of cardiovascular events in people with diabetes: a position statement of the American Diabetes Association, a scientific statement of the American Heart Association, and an expert consensus document of the American College
Topics: American Heart Association; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Melli | 2010 |
Aspirin use in elderly women receiving medication therapy management services.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Comorbidity; Contraindications; Diabetes | 2010 |
The effect of aspirin on atherogenic diet-induced diabetes mellitus.
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Glucose; Cholestero | 2011 |
Clinical data extraction and feedback in general practice: a case study from Australian primary care.
Topics: Aspirin; Australia; Coronary Disease; Diabetes Mellitus; Glycated Hemoglobin; Humans; Hydroxymethylg | 2010 |
Antiplatelet therapy for every diabetic person?
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors; Random | 2011 |
Ischemic stroke in patients receiving aspirin.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Argentina; Aspirin; Brain Ischemia; Chi-Square Dis | 2012 |
Comparison of characteristics, management practices, and outcomes of patients between the global registry and the gulf registry of acute coronary events.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Angiotensin Receptor Antagonists; Aspiri | 2011 |
Aspirin for CV prevention -- for which patients?
Topics: Aged; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Drug Resistance; Female; Fibrinolytic Age | 2011 |
Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane.
Topics: Adult; Aged; Aged, 80 and over; Aldehyde Reductase; Aspirin; Blood Glucose; Case-Control Studies; Co | 2011 |
Potential implications of coronary artery calcium testing for guiding aspirin use among asymptomatic individuals with diabetes.
Topics: Adult; Aged; Aspirin; Calcinosis; Coronary Artery Disease; Diabetes Mellitus; Female; Humans; Male; | 2012 |
Inhibition of platelet aggregation by prostaglandin E1 (PGE1) in diabetic patients during therapy with clopidogrel and aspirin.
Topics: Adenosine Diphosphate; Aged; Alprostadil; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel; Cytoc | 2013 |
The prevalence, risk factors and prognosis of aspirin resistance in elderly male patients with cardiovascular disease.
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Drug Resistance; Human | 2012 |
Association of aspirin use with major bleeding in patients with and without diabetes.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Case-Control Studies; Cohort Studi | 2012 |
Hemorrhagic complications associated with aspirin: an underestimated hazard in clinical practice?
Topics: Aspirin; Diabetes Mellitus; Female; Gastrointestinal Hemorrhage; Humans; Intracranial Hemorrhages; M | 2012 |
Diabetes: Does aspirin increase the risk of major bleeds?
Topics: Aspirin; Diabetes Mellitus; Hemorrhage; Humans; Platelet Aggregation Inhibitors; Risk Assessment | 2012 |
Clinical efficacy and safety of biodegradable polymer-based sirolimus-eluting stents in patients with diabetes mellitus insight from the 4-year results of the create study.
Topics: Absorbable Implants; Aged; Aspirin; Cardiovascular Agents; Chi-Square Distribution; Clopidogrel; Cor | 2013 |
Benefits and risks of aspirin use.
Topics: Aspirin; Diabetes Mellitus; Female; Gastrointestinal Hemorrhage; Humans; Intracranial Hemorrhages; M | 2012 |
Benefits and risks of aspirin use.
Topics: Aspirin; Diabetes Mellitus; Female; Gastrointestinal Hemorrhage; Humans; Intracranial Hemorrhages; M | 2012 |
Utilization of statins and aspirin among patients with diabetes and hyperlipidemia: Taiwan, 1998-2006.
Topics: Adult; Aged; Aspirin; Coronary Disease; Diabetes Mellitus; Drug Utilization; Female; Humans; Hydroxy | 2012 |
Pharmacologic treatment in dialysis patients hospitalized for cardiovascular reasons: do we follow the guidelines?
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting E | 2013 |
Pharmaceutical care for patients with acute myocardial infarction in Hungary.
Topics: Acute Disease; Adult; Aged; Aspirin; Clopidogrel; Comorbidity; Diabetes Mellitus; Drug Therapy, Comb | 2013 |
Unmet needs of diabetic patients.
Topics: Aspirin; Cardiovascular Diseases; Cholesterol, LDL; Diabetes Mellitus; Health Services Needs and Dem | 2012 |
Benefits of aspirin and beta-blockade after myocardial infarction in patients with chronic kidney disease.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Dis | 2002 |
Aspirin therapy in diabetes.
Topics: Aspirin; Diabetes Mellitus; Diabetic Angiopathies; Humans; Meta-Analysis as Topic; Quality Assurance | 2003 |
Prior aspirin use in unstable angina patients with modified plasma inflammatory markers and endothelial nitric oxide synthase in neutrophils.
Topics: Aged; Angina, Unstable; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Case-Control S | 2002 |
Aspirin and diabetes: inhibition of amylin aggregation by nonsteroidal anti-inflammatory drugs.
Topics: Amyloid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Circular Dichroism; Congo Red; Cyclooxyge | 2003 |
Smoking and the risk of hemorrhagic stroke in men.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; beta Carotene; Body Mass Ind | 2003 |
Guidelines for improving the care of the older person with diabetes mellitus.
Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M | 2003 |
Guidelines for improving the care of the older person with diabetes mellitus.
Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M | 2003 |
Guidelines for improving the care of the older person with diabetes mellitus.
Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M | 2003 |
Guidelines for improving the care of the older person with diabetes mellitus.
Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M | 2003 |
Clopidogrel and percutaneous coronary interventions.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Diabetes Mellitus; Drug Administration Schedul | 2003 |
[Use of anti-aggregant drugs in primary and secondary cardiovascular prevention in diabetics in town and country in the León area].
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Primary Health Care; Primary Prevention | 2003 |
Income-related differences in the use of evidence-based therapies in older persons with diabetes mellitus in for-profit managed care.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cohort Studies; Data Collection; Diabetes M | 2003 |
Aspirin and diabetes mellitus.
Topics: Aspirin; Diabetes Mellitus; Humans; Medical Records; Rheumatic Diseases | 1957 |
ASPIRIN and diabetes.
Topics: Aspirin; Diabetes Mellitus; Humans | 1958 |
Dinitrophenol and diabetes mellitus: a comparison with salicylate.
Topics: Aspirin; Diabetes Mellitus; Dinitrophenols; Humans; Nitrophenols; Salicylates | 1958 |
The insulin equivalence of salicylate.
Topics: Aspirin; Diabetes Mellitus; Humans; Insulin; Salicylates | 1959 |
[Acetylsalicylic acid therapy of diabetes mellitus].
Topics: Aspirin; Diabetes Mellitus; Humans | 1958 |
Reappraisal of the hypoglycemic action of acetylsalicylate.
Topics: Aspirin; Blood Glucose; Diabetes Mellitus; Humans; Hypoglycemic Agents | 1959 |
[HYPOGLYCEMIC ACTION OF ACETYLSALICYLIC ACID IN DIABETES IN OLD AGE].
Topics: Aspirin; Diabetes Mellitus; Geriatrics; Humans; Hypoglycemic Agents | 1963 |
[ASPIRIN AND DIABETES. NEW FINDINGS ON THE BLOOD SUGAR DECREASING EFFECTS OF SALICYL PREPARATIONS].
Topics: Aspirin; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; England; Humans; Pancreatic Dise | 1963 |
A SIMPLIFIED VIEW OF FLUID THERAPY.
Topics: Acidosis; Adrenal Insufficiency; Aspirin; Calcium; Child; Cystic Fibrosis; Dehydration; Diabetes Mel | 1964 |
ACUTE RENAL FAILURE FOLLOWING ACETOPHENETIDIN INGESTION.
Topics: Acidosis; Acute Kidney Injury; Aspirin; Caffeine; Diabetes Mellitus; Diabetic Ketoacidosis; Diagnosi | 1964 |
LONG-TERM TREATMENT OF A PATIENT WITH RHEUMATOID ARTHRITIS.
Topics: Arthritis, Rheumatoid; Aspirin; Braces; Casts, Surgical; Contracture; Diabetes Mellitus; Drug Therap | 1964 |
INHIBITION OF THE MOBILIZATION OF FREE FATTY ACIDS FROM ADIPOSE TISSUE IN DIABETES. II. EFFECT OF NICOTINIC ACID AND ACETYLSALICYLATE ON BLOOD GLUCOSE IN HUMAN DIABETICS.
Topics: Adipose Tissue; Aspirin; Blood Glucose; Diabetes Mellitus; Fatty Acids; Fatty Acids, Nonesterified; | 1965 |
Cardiology Patient Page. C-reactive protein: a simple test to help predict risk of heart attack and stroke.
Topics: Age Factors; Aspirin; C-Reactive Protein; Cholesterol; Diabetes Mellitus; Female; Heart Diseases; Hu | 2003 |
Decisional attributes of patients with diabetes: the aspirin choice.
Topics: Adult; Aged; Aspirin; Attitude to Health; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes | 2003 |
Aspirin therapy in diabetes.
Topics: Aspirin; Diabetes Mellitus; Diabetic Angiopathies; Female; Humans; Male; Platelet Aggregation Inhibi | 2004 |
[Acetylsalicylic acid consumption in patients with diabetes mellitus].
Topics: Adult; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Female; Humans; M | 2004 |
[Underutilization of acetylsalicylic acid of cardiovascular prevention in patients with diabetes mellitus].
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Humans; Platelet Aggrega | 2004 |
Effect of aspirin upon glycosuria of the partially depancreatized rat.
Topics: Animals; Aspirin; Diabetes Mellitus; Glycosuria; Rats | 1950 |
[Cardiovascular risk stratification in general practice].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Blood Pressure; Cholesterol; Coronar | 2004 |
[Recommendations for cardiovascular rehabilitation in diabetes mellitus].
Topics: Adrenergic beta-Antagonists; Angina, Unstable; Angioplasty, Balloon; Aspirin; Blood Glucose; Cardiov | 2003 |
Risk factors for incident cortical and posterior subcapsular lens opacities in the Barbados Eye Studies.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Barbados; Black People; Cataract; Cohort Studies; Diabetes | 2004 |
Aspirin resistance in diabetic patients.
Topics: Aspirin; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug Resistance; Humans; Platelet Aggregation | 2004 |
Consensus statement for the prevention of vascular disease.
Topics: Aged; Aspirin; Atrial Fibrillation; Australia; Diabetes Complications; Diabetes Mellitus; Family Pra | 2004 |
Soluble CD40 ligand, soluble P-selectin, interleukin-6, and tissue factor in diabetes mellitus: relationships to cardiovascular disease and risk factor intervention.
Topics: Aged; Aspirin; Biomarkers; Blood Coagulation; Cardiovascular Diseases; CD40 Ligand; Cohort Studies; | 2004 |
Preventing recurrent events long term after coronary artery bypass graft: suboptimal use of medications in a population study.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Aspirin; | 2004 |
[Aspirin use in patients with diabetes mellitus].
Topics: Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Female; Humans; Male; P | 2004 |
[Aspirin use in patients with diabetes mellitus].
Topics: Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Humans; Platelet Aggreg | 2004 |
[Aspirin use in patients with diabetes mellitus].
Topics: Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitu | 2004 |
[Aspirin use in patients with diabetes mellitus].
Topics: Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitu | 2004 |
Explaining the increase in coronary heart disease mortality in Beijing between 1984 and 1999.
Topics: Adult; Aged; Antihypertensive Agents; Aspirin; Cardiovascular Agents; China; Coronary Disease; Devel | 2004 |
Sub-optimal drug treatment of diabetes and cardiovascular risk in diabetic patients in Turkey. A countrywide survey.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihyperte | 2004 |
Predictors of cognitive dysfunction in patients with systemic lupus erythematosus.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antiphospholipid; Aspirin; Autoant | 2005 |
Cardiovascular risk in patients with type 2 diabetes.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Arteriosclerosis; Aspirin; Ca | 2005 |
[Prophylaxis of stroke].
Topics: Age Factors; Aged; Angioplasty, Balloon; Anticoagulants; Antihypertensive Agents; Aspirin; Atrial Fi | 2005 |
Aspirin prophylaxis in diabetes mellitus.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Humans; Treatment Outcome | 2005 |
Progress of leukoaraiosis is inhibited by correction of platelet hyper-aggregability.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Brain; Dementia, Va | 2005 |
A new definition of aspirin non-responsiveness by platelet function analyzer-100 and its predictors.
Topics: Aspirin; Coronary Artery Disease; Diabetes Mellitus; Diet; Drug Resistance; Female; Humans; Male; Mi | 2006 |
Is aspirin effective in diabetic patients? Yes.
Topics: Aspirin; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Humans; Treatment Outcome | 2005 |
Is aspirin effective in diabetic patients? No.
Topics: Aspirin; Diabetes Complications; Diabetes Mellitus; Hemorrhage; Humans; Risk Assessment; Treatment F | 2005 |
Influence of aspirin resistance on platelet function profiles in patients on long-term aspirin and clopidogrel after percutaneous coronary intervention.
Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Collagen Type I; | 2006 |
Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients.
Topics: Adult; Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Coronary Artery Disease; Cyclooxygenase 1 | 2006 |
Clopidogrel withdrawal is associated with proinflammatory and prothrombotic effects in patients with diabetes and coronary artery disease.
Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus; Fema | 2006 |
[Postoperative antithrombotic treatment in diabetic patients].
Topics: Anticoagulants; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Artery Disease; Diabetes Mell | 2006 |
Increased cardiovascular risk associated with diabetes in Dallas County.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Blood Glucose; Calcium; Cardiovascular Dis | 2006 |
Acetylsalicylic acid (ASA) use among Polish adults with diabetes mellitus.
Topics: Adult; Aspirin; Cardiovascular Diseases; Causality; Comorbidity; Diabetes Complications; Diabetes Me | 2005 |
Increased basal platelet activity, plasma adiponectin levels, and diabetes mellitus are associated with poor platelet responsiveness to in vitro effect of aspirin.
Topics: Adiponectin; Adult; Aspirin; Blood Platelets; Diabetes Mellitus; Drug Resistance; Humans; In Vitro T | 2007 |
Evaluation of the uses of aspirin, statins and ACEIs/ARBs in a diabetes outpatient population in southern Thailand.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cross-Sectional S | 2007 |
Iron status and the use of non-steroidal anti-inflammatory drugs in hemodialysis patients.
Topics: Aged; Anemia, Iron-Deficiency; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; | 2007 |
Long-term safety and efficacy of drug-eluting stents: two-year results of the REAL (REgistro AngiopLastiche dell'Emilia Romagna) multicenter registry.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Combined Modality Therapy; Coronary Angi | 2007 |
Use of aspirin for primary and secondary prevention of cardiovascular disease in diabetic patients in an ambulatory care setting in Spain.
Topics: Aged; Ambulatory Care; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Female; Follow-Up Studie | 2007 |
Health issues in the Arab American community. The use of glucose-lowering agents and aspirin among Arab Americans with diabetes.
Topics: Aged; Arabs; Aspirin; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Int | 2007 |
4 ways to save your heart.
Topics: Aspirin; Blood Glucose; Blood Pressure; Diabetes Mellitus; Diabetic Angiopathies; Heart; Humans; Lip | 2008 |
[Antiplatelet treatment after acute and chronic ischemic heart and brain events is insufficient according to recommendations].
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angina, Unstable; Aspirin; | 2008 |
[Behavior of alpha-ketoacids after certain hypoglycemic agents].
Topics: Animals; Aspirin; Biguanides; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Insulin; Keto | 1967 |
Acetylsalicyclic acid in diabetes.
Topics: Aspirin; Diabetes Mellitus; Humans; Insulin; Insulin Secretion; Lysine; Prostaglandins E | 1981 |
Secondary prevention of coronary heart disease.
Topics: Adrenergic beta-Antagonists; Anticoagulants; Aspirin; Coronary Disease; Diabetes Mellitus; Feeding B | 1984 |
Treatment of canine spontaneous diabetes mellitus with aspirin.
Topics: Animals; Aspirin; Cyclic AMP; Cyclic GMP; Diabetes Mellitus; Diabetic Retinopathy; Disease Models, A | 1980 |
Maturity-onset diabetes mellitus--toward a physiological appropriate management.
Topics: Amino Acids; Aspirin; Carnitine; Chromium; Diabetes Mellitus; Dietary Fats; Dietary Fiber; Fasting; | 1981 |
Aspirin and prostacyclin treatment of diabetic dogs.
Topics: Animals; Aspirin; Cyclic AMP; Diabetes Mellitus; Diabetic Retinopathy; Dog Diseases; Dogs; Epoproste | 1983 |
Increased secretion of insulin but unchanged secretion of growth hormone in hyperglycaemic type II diabetics treated with acetyl-salicylic acid.
Topics: Aged; Arginine; Aspirin; Blood Glucose; Diabetes Mellitus; Growth Hormone; Humans; Insulin; Insulin | 1983 |
[Treatment of diabetes by oral administration of hypoglycemic agents].
Topics: Administration, Oral; Aspirin; Diabetes Mellitus; Drug Therapy, Combination; Humans; Hypoglycemic Ag | 1984 |
Urinary excretion of 2,3-dinor-thromboxane B2 in man under normal conditions, following drugs and during some pathological conditions.
Topics: Acetaminophen; Adult; Amino Acid Metabolism, Inborn Errors; Aspirin; Circadian Rhythm; Diabetes Mell | 1984 |
[Effect of the single administration of acetylsalicylic acid and dipyridamole on microcirculation in patients with diabetes mellitus].
Topics: Adolescent; Adult; Aged; Aspirin; Diabetes Mellitus; Dipyridamole; Female; Humans; Male; Microcircul | 1983 |
Enhanced in vivo platelet activation in diabetes mellitus.
Topics: Adult; Aged; Aging; Aspirin; Blood Platelets; Calcium Channel Blockers; Cardiovascular Diseases; Dia | 1982 |
Platelet adhesion to collagen in normal and von Willebrand's disease subjects.
Topics: Animals; Aspirin; Blood Platelets; Collagen; Diabetes Mellitus; Dipyridamole; Factor VIII; Humans; K | 1980 |
Impaired insulin secretion in human diabetes mellitus. II. A possible role for prostaglandins.
Topics: Adult; Arginine; Aspirin; Blood Glucose; Diabetes Mellitus; Female; Glucose; Humans; Insulin; Insuli | 1981 |
Availability of endothelial von Willebrand factor and platelet function in diabetic patients infused with a vasopressin analogue.
Topics: Adenosine Diphosphate; Adult; Antigens; Arginine Vasopressin; Aspirin; Blood Coagulation Factors; De | 1982 |
Clinical trials and statistical verdicts: probable grounds for appeal.
Topics: Aspirin; Clinical Trials as Topic; Coronary Disease; Diabetes Mellitus; Humans; Jurisprudence; Lung | 1983 |
Platelet factor 4 levels in patients with coronary artery disease.
Topics: Acute Disease; Adult; Aged; Aspirin; Blood Coagulation Factors; Coronary Artery Bypass; Coronary Dis | 1981 |
Acute effects of acetylsalicylic acid on blood glucose and insulin in non-insulin dependent diabetes.
Topics: Aspirin; Blood Glucose; Diabetes Mellitus; Female; Glipizide; Humans; Insulin; Male | 1980 |
Atherosclerosis in diabetes mellitus.
Topics: Arteriosclerosis; Aspirin; Blood Platelets; Diabetes Complications; Diabetes Mellitus; Epoprostenol; | 1981 |
The effect of acetylsalicylic acid on plasma glucose and the response of glucose regulatory hormones to intravenous glucose and arginine in insulin treated diabetics and normal subjects.
Topics: Adult; Aged; Arginine; Aspirin; Blood Glucose; C-Peptide; Diabetes Mellitus; Female; Glucagon; Gluco | 1981 |
A role for endogenous prostaglandins in defective glucose potentiation of nonglucose insulin secretagogues in diabetics.
Topics: Adult; Aged; Arginine; Aspirin; Blood Glucose; Diabetes Mellitus; Glucose; Humans; Insulin; Insulin | 1981 |
Effect of acetylsalicylic acid on blood glucose and glucose regulatory hormones in mild diabetes.
Topics: Adult; Aged; Aspirin; Blood Glucose; Diabetes Mellitus; Female; Gastric Inhibitory Polypeptide; Gast | 1982 |
Secondary prevention in myocardial infarction survivors.
Topics: Anticoagulants; Aspirin; Diabetes Mellitus; Diet, Reducing; Humans; Hypertension; Lipids; Myocardial | 1982 |
[Several methods of treatment of diabetes mellitus and its complications].
Topics: Acid-Base Equilibrium; Adult; Aspirin; Blood Viscosity; Diabetes Mellitus; Diabetic Angiopathies; Di | 1982 |
Effect of aspirin on platelet aggregation in diabetes mellitus.
Topics: Arachidonic Acids; Aspirin; Collagen; Diabetes Mellitus; Diabetic Retinopathy; Humans; Middle Aged; | 1982 |
[Diamicron and micristin in the complex treatment of diabetes mellitus].
Topics: Adult; Aspirin; Cellulose; Crystallization; Diabetes Mellitus; Drug Therapy, Combination; Gliclazide | 1982 |
Effects of acetylsalicylic acid on plasma glucose, free fatty acid, betahydroxybutyrate, glucagon and C-peptide responses to salbutamol in insulin-dependent diabetic subjects.
Topics: Adult; Albuterol; Aspirin; Blood Glucose; C-Peptide; Diabetes Mellitus; Fatty Acids, Nonesterified; | 1981 |
Platelet life-span in diabetics with and without retinopathy.
Topics: Adult; Aspirin; Blood Glucose; Blood Platelets; Cell Survival; Diabetes Complications; Diabetes Mell | 1981 |
Which diabetic patients should be taking aspirin?
Topics: Aspirin; Diabetes Mellitus; Diabetic Angiopathies; Humans; Platelet Aggregation Inhibitors; Risk Fac | 1995 |
Chromatographic evaluation of minor hemoglobins: clinical significance of hemoglobin A1d, comparison with hemoglobin A1c, and possible interferences.
Topics: Aspirin; Chromatography, Affinity; Chromatography, High Pressure Liquid; Diabetes Mellitus; Erythroc | 1995 |
Glycation-induced inactivation of malate dehydrogenase protection by aspirin and a lens molecular chaperone, alpha-crystallin.
Topics: Animals; Aspirin; Carbohydrates; Cataract; Crystallins; Diabetes Complications; Diabetes Mellitus; G | 1996 |
Presence and treatment of vascular risk factors in patients with vascular cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspirin; Cognition Disorders; Dementia; Diabetes Complic | 1997 |
Secular trends in stroke mortality in African Americans: the role of urbanization, diabetes and obesity.
Topics: Adult; Aged; Aspirin; Black People; Cerebrovascular Disorders; Diabetes Mellitus; Female; Fibrinolyt | 1997 |
[Should one prescribe aspirin for all diabetics?].
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Humans; Platelet Aggrega | 1997 |
Management of patients with diabetes after heart attack: a population-based study of 1982 patients from a heart disease register.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Austral | 1998 |
Augmented platelet aggregation as predictor of reocclusion after thrombolysis in acute myocardial infarction.
Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Anticoagulants; Antithrombin III; Aspirin; Co | 1998 |
Comparison of secondary prevention measures after myocardial infarction in subjects with and without diabetes mellitus.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Blood Glucose; | 1999 |
Aspirin and risk of hemorrhagic stroke.
Topics: Aspirin; Cerebral Hemorrhage; Diabetes Mellitus; Humans; Platelet Aggregation Inhibitors; Risk | 1999 |
Meeting report of the ASPET-Ray Fuller Symposium: insulin resistance in diabetes and hypertension: syndrome X and beyond.
Topics: Aspirin; Cardiovascular Diseases; Cholesterol, HDL; Diabetes Complications; Diabetes Mellitus; Endot | 2000 |
Sex differences and similarities in the management and outcome of stroke patients.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Cohort Studies; Comorbidity; | 2000 |
Antiplatelet drugs in cardiovascular prevention: coronary events and stroke: primary prevention.
Topics: Aspirin; Carotid Stenosis; Cost-Benefit Analysis; Diabetes Mellitus; Digestive System; Female; Human | 2000 |
Aspirin use among adults with diabetes: estimates from the Third National Health and Nutrition Examination Survey.
Topics: Adult; Albuminuria; Angina Pectoris; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabe | 2001 |
Treatment of cardiac risk factors in diabetic patients: How well do we follow the guidelines?
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Blood Pressure | 2001 |
Acute myocardial infarction in the young--The University of Michigan experience.
Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Anticoagulants; Aspirin; Coronary Artery B | 2002 |
Aspirin therapy in diabetes.
Topics: Aspirin; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Humans; Platelet Aggre | 2000 |
Aspirin use and counseling about aspirin among patients with diabetes.
Topics: Aged; Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Angiopathies; Female; Health Kno | 2002 |
Methods for detection of hypersensitive platelets. Philadelphia, June 1977.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Coagulation Tests; Blood Platelets; Cardiovascular | 1978 |
Classification of platelet aggregation patterns with two ADP solutions (the double-ADP method) and its clinical application to diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Aged; Aging; Aspirin; Blood Glucose; Cholesterol; Diabetes Mellitus; D | 1977 |
Diclofenac sodium (Voltarol): drug interactions and special studies.
Topics: Adult; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Blood Coagulation Factors; Blood Glucose; | 1979 |
Acetylsalicylic acid augments insulin and C-peptide responses to arginine in diabetes mellitus.
Topics: Adult; Arginine; Aspirin; Blood Glucose; C-Peptide; Diabetes Mellitus; Female; Humans; Insulin; Insu | 1979 |
Reduced fibrinogen survival in diabetes mellitus. A reversible phenomenon.
Topics: Adult; Aged; Aspirin; Chromatography, DEAE-Cellulose; Chromatography, Gel; Diabetes Mellitus; Dipyri | 1979 |
Platelet survival in diabetes mellitus using an aspirin-labelling technique.
Topics: Adolescent; Adult; Aged; Aspirin; Blood Platelets; Cell Survival; Diabetes Mellitus; Female; Humans; | 1979 |
Dietary prevention of atherosclerosis: new aspects.
Topics: Animals; Arteriosclerosis; Aspirin; Cholesterol, Dietary; Diabetes Mellitus; Diet; Heart; Hypertensi | 1979 |
[The electrophoretic mobility of platelets. Short review of the literature and contribution with personal experience (author's transl)].
Topics: Adolescent; Adult; Aspirin; Blood Coagulation; Blood Platelets; Contraceptives, Oral; Diabetes Melli | 1978 |
[Which anti-inflammatory and which analgesic agents should one select for diabetics?].
Topics: Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Diabetes Complications; Diabet | 1978 |
[Significance of two concentrations of adenosine diphosphate inducing platelet aggregation in patients with diabetes mellitus (author's transl)].
Topics: Adenosine Diphosphate; Adult; Aged; Aging; Aspirin; Diabetes Mellitus; Diabetic Retinopathy; Female; | 1978 |
Altered platelet function in diabetes mellitus.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Cyclooxygenase | 1976 |
Induced bleeding changes with aspirin in various tolerant and intolerant patient groups.
Topics: Aspirin; Blood Coagulation Tests; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Diabetes Melli | 1975 |
Increased platelet aggregation in early diabetus mellitus.
Topics: Adenosine Diphosphate; Administration, Oral; Aspirin; Collagen; Diabetes Mellitus; Diabetic Angiopat | 1975 |
Diabetes mellitus and insulin in an aspirin sensitive asthmatic.
Topics: Aspirin; Asthma; Azo Compounds; Benzenesulfonates; Coloring Agents; Diabetes Complications; Diabetes | 1976 |
[Cardiovascular risk factors and restenosis after PTCA].
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Combined Modality Therapy; Coronary Angiography; Coro | 1992 |
Ischemic stroke. How to keep the first one from happening.
Topics: Aspirin; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hyperlipidemias; Hypertension; I | 1991 |
Non-enzymatic glycosylation of keratin from the stratum corneum of the diabetic foot.
Topics: Adult; Aged; Aspirin; Diabetes Mellitus; Epidermis; Foot; Glucose; Glycated Hemoglobin; Humans; In V | 1985 |
[Determination of human sensitivity to the antiaggregation action of acetylsalicylic acid].
Topics: Arteriosclerosis; Aspirin; Diabetes Mellitus; Humans; Methods; Myocardial Infarction; Platelet Aggre | 1986 |
Blood lipid peroxides in TIA: relation to platelet function and metabolic profile.
Topics: Administration, Oral; Aged; Arteriosclerosis; Aspirin; Blood Glucose; Blood Platelets; Coronary Dise | 1989 |
In vivo measurement of thromboxane B2 and 6-keto-prostaglandin F1 alpha in humans in response to a standardized vascular injury and the influence of aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Bleeding Time; Diabetes Mellitus; Dose-Response Relati | 1989 |
[Study of plasma beta thromboglobulin level induced by heparin in diabetic patients].
Topics: Adult; Aged; Aspirin; beta-Thromboglobulin; Diabetes Mellitus; Diabetic Angiopathies; Female; Hepari | 1988 |
Pathways responsible for platelet hypersensitivity in rats with diabetes. I. Streptozocin-induced diabetes.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Colla | 1986 |
Trial of repeated low-dose aspirin in diabetic angiopathy.
Topics: Adenosine Triphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collag | 1986 |
Plasma thromboxane and prostacyclin metabolite ratio in atherosclerosis and diabetes mellitus.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arteriosclerosis; Aspirin; Diabetes Mellitus; Epoprostenol; Fem | 1987 |
[Acylpyrin and glucose homeostasis in diabetes mellitus].
Topics: Adult; Aged; Aspirin; Diabetes Mellitus; Glucose; Homeostasis; Humans; Middle Aged; Receptor, Insuli | 1988 |
[Effect of acetylsalicylic acid on thrombocyte function in patients with diabetes mellitus (review of the literature)].
Topics: Aspirin; Blood Platelets; Diabetes Mellitus; Diabetic Angiopathies; Humans | 1987 |
Non-enzymatic acetylation of proteins by aspirin as protection against the secondary complications of diabetes mellitus.
Topics: Acetylation; Aspirin; Diabetes Complications; Diabetes Mellitus; Glycosylation; Humans; In Vitro Tec | 1986 |
Increased thromboxane B2 excretion in diabetes mellitus.
Topics: Adult; Aspirin; Blood Platelets; Diabetes Mellitus; Female; Glomerular Filtration Rate; Humans; Kidn | 1987 |
The effects on lipids, blood viscosity and platelet aggregation of combined use of niceritrol (Perycit) and a low dose of acetylsalicylic acid.
Topics: Adult; Aged; Arteriosclerosis; Aspirin; Blood Viscosity; Diabetes Mellitus; Female; Fibrinogen; Huma | 1985 |
[Arachidonic acids].
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Diabetes Mellitus; Humans; Methods; Myeloproliferative | 1985 |
Treatment of atherosclerosis and thrombosis with aspirin.
Topics: Adult; Age Factors; Animals; Arteriosclerosis; Aspirin; Blood Platelets; Coronary Disease; Diabetes | 1972 |
The effect of variation of lipolysis after nicotinic acid and acetylsalicylate on blood concentrations of 3-hydroxybutyrate and acetoacetate in starving subjects.
Topics: Acetoacetates; Adolescent; Adult; Aspirin; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterif | 1970 |
The effect of some drugs on oxalic acid excretion in urine.
Topics: Ascorbic Acid; Aspirin; Asthma; Calcium; Citrates; Coronary Disease; Depression, Chemical; Diabetes | 1970 |
Editorial: Aspirin and diabetic retinopathy.
Topics: Aspirin; Diabetes Mellitus; Diabetic Retinopathy; Humans; Platelet Adhesiveness; Time Factors | 1974 |
Regular aspirin intake and acute myocardial infarction.
Topics: Adult; Age Factors; Aged; Arthritis; Aspirin; Diabetes Mellitus; Female; Humans; Hypertension; Male; | 1974 |
Cystitis emphysematosa.
Topics: Adult; Aspirin; Cephalexin; Cystitis; Cystoscopy; Diabetes Complications; Diabetes Mellitus; Diet, D | 1974 |
Increased platelet aggregation in diabetes mellitus.
Topics: Adenosine Diphosphate; Aspirin; Blood Chemical Analysis; Blood Proteins; Creatinine; Diabetes Mellit | 1972 |
Inhibition of glucose oxidase paper tests by reducing metabolites.
Topics: Adult; Alkaptonuria; Aspirin; Diabetes Complications; Diabetes Mellitus; Dihydroxyphenylalanine; Fal | 1970 |
Studies on salicylates and complement in diabetes.
Topics: Adolescent; Adult; Aspirin; Complement System Proteins; Diabetes Mellitus; Diabetic Retinopathy; Fem | 1966 |