aspirin has been researched along with Dementia, Vascular in 19 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Dementia, Vascular: An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
| Excerpt | Relevance | Reference |
|---|---|---|
| "CSHA-1 participants with vascular dementia performed worse in copying pentagons and writing subtests of modified Mini-Mental State Examination test than participants with probable Alzheimer's disease." | 5.43 | Simple Neuropsychological Tests May Identify Participants in Whom Aspirin Use Is Associated With Lower Dementia Incidence: The Canadian Study of Health and Aging. ( Hachinski, V; Oveisgharan, S, 2016) |
| "Aspirin given as a platelet antiaggregant has been shown to be effective for secondary prevention both in cardiology (myocardial infarction, uncontrolled angina pectoris, coronary bypass, etc." | 4.79 | [From heart to brain and from brain to heart: impact of an anticoagulant treatment with aspirin in secondary prevention]. ( Chollet, F, 1994) |
| "Recent data indicate that patients with vascular dementia (VaD) show a cholinergic deficit." | 2.71 | Rivastigmine superior to aspirin plus nimodipine in subcortical vascular dementia: an open, 16-month, comparative study. ( Antonello, RM; Bava, A; Cazzato, G; Griggio, S; Moretti, R; Torre, P; Ukmar, M, 2004) |
| "As part of a multicenter treatment trial of vascular dementia, this method was then used to analyze MR films in 13 patients with vascular dementia who all had an MR study at baseline and at 1 year." | 2.68 | Volumetric measurement of multifocal brain lesions. Implications for treatment trials of vascular dementia and multiple sclerosis. ( Broderick, JP; Dhawan, AP; Gaskill, M; Khoury, J; Narayan, S, 1996) |
| "However, unlike stroke, treatment of hyperlipidemia with statin class drugs or treatment of blood clotting abnormalities with acetylsalicylic acid do not appear to have an effect on VaD incidence or progression." | 2.48 | Pharmacological prevention and treatment of vascular dementia: approaches and perspectives. ( Baskys, A; Cheng, JX, 2012) |
| "Vascular dementia is one of the most frequently occurring dementia syndromes." | 2.42 | [Vascular dementia]. ( de Leeuw, FE; van Gijn, J, 2004) |
| "For patients with a diagnosis of vascular dementia there is evidence that aspirin is widely prescribed - in one study, completed by geriatricians and psychiatrists in the UK, 80% of patients with cognitive impairment (with vascular risk factors) were prescribed aspirin." | 2.41 | Aspirin for vascular dementia. ( Orrell, M; Rands, G; Spector, A; Williams, PS, 2000) |
| "For patients with a diagnosis of vascular dementia there is evidence that aspirin is widely prescribed - in one study, completed by geriatricians and psychiatrists in the UK, 80% of patients with cognitive impairment (with vascular risk factors) were prescribed aspirin." | 2.41 | Aspirin for vascular dementia. ( Orrel, M; Rands, G; Spector, A; Williams, PS, 2000) |
| "CSHA-1 participants with vascular dementia performed worse in copying pentagons and writing subtests of modified Mini-Mental State Examination test than participants with probable Alzheimer's disease." | 1.43 | Simple Neuropsychological Tests May Identify Participants in Whom Aspirin Use Is Associated With Lower Dementia Incidence: The Canadian Study of Health and Aging. ( Hachinski, V; Oveisgharan, S, 2016) |
| "The progress of leukoaraiosis is greatly inhibited by long-term correction of platelet hyper-aggregability." | 1.33 | Progress of leukoaraiosis is inhibited by correction of platelet hyper-aggregability. ( Fujita, S; Fukushima, K; Kawaguchi, T; Uehara, T, 2005) |
| "Aspirin was associated with a trend towards increased time to institutionalization (39 vs 22 months, p < 0." | 1.32 | Does aspirin affect outcome in vascular dementia? A retrospective case-notes analysis. ( Devine, ME; Rands, G, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Knopman, DS | 1 |
| Petersen, RC | 1 |
| Servello, A | 1 |
| Andreozzi, P | 1 |
| Bechini, F | 1 |
| De Angelis, R | 1 |
| Pontecorvo, ML | 1 |
| Vulcano, A | 1 |
| Cerra, E | 1 |
| Vigliotta, MT | 1 |
| Artini, M | 1 |
| Selan, L | 1 |
| Ettorre, E | 1 |
| Patrono, C | 2 |
| Oveisgharan, S | 1 |
| Hachinski, V | 2 |
| Cox, M | 1 |
| Bisangwa, S | 1 |
| Herpich, F | 1 |
| Crudele, A | 1 |
| Pineda, C | 1 |
| Baskys, A | 1 |
| Cheng, JX | 1 |
| Devine, ME | 1 |
| Rands, G | 3 |
| Nelson, M | 1 |
| Reid, C | 1 |
| Beilin, L | 1 |
| Donnan, G | 1 |
| Johnston, C | 1 |
| Krum, H | 1 |
| Storey, E | 1 |
| Tonkin, A | 1 |
| McNeil, J | 1 |
| Moretti, R | 1 |
| Torre, P | 1 |
| Antonello, RM | 1 |
| Cazzato, G | 1 |
| Griggio, S | 1 |
| Ukmar, M | 1 |
| Bava, A | 1 |
| de Leeuw, FE | 1 |
| van Gijn, J | 1 |
| Fujita, S | 1 |
| Kawaguchi, T | 1 |
| Uehara, T | 1 |
| Fukushima, K | 1 |
| Hillemacher, T | 1 |
| Bleich, S | 1 |
| Wiltfang, J | 1 |
| Weber, M | 1 |
| Kornhuber, J | 1 |
| Frieling, H | 1 |
| Tozer, R | 1 |
| Hastie, IR | 1 |
| Chollet, F | 1 |
| Broderick, JP | 1 |
| Narayan, S | 1 |
| Gaskill, M | 1 |
| Dhawan, AP | 1 |
| Khoury, J | 1 |
| Molnar, FJ | 1 |
| Man-Son-Hing, M | 1 |
| St John, P | 1 |
| Brymer, C | 1 |
| Rockwood, K | 1 |
| van Kooten, F | 1 |
| Ciabattoni, G | 1 |
| Koudstaal, PJ | 1 |
| Grobbee, DE | 1 |
| Kluft, C | 1 |
| Williams, PS | 2 |
| Spector, A | 2 |
| Orrell, M | 1 |
| Orrel, M | 1 |
6 reviews available for aspirin and Dementia, Vascular
| Article | Year |
|---|---|
The Multifaceted Clinical Readouts of Platelet Inhibition by Low-Dose Aspirin.
Topics: Aspirin; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Dementia, Vascular; Human | 2015 |
Pharmacological prevention and treatment of vascular dementia: approaches and perspectives.
Topics: Alzheimer Disease; Antihypertensive Agents; Aspirin; Cholinesterase Inhibitors; Cognition; Dementia, | 2012 |
[Vascular dementia].
Topics: Aged; Aged, 80 and over; Arteriosclerosis; Aspirin; Cyclooxygenase Inhibitors; Dementia, Vascular; F | 2004 |
[From heart to brain and from brain to heart: impact of an anticoagulant treatment with aspirin in secondary prevention].
Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Dementia, Vascular; Humans; Ischemic Attack, Transient | 1994 |
Aspirin for vascular dementia.
Topics: Aspirin; Cognition Disorders; Dementia, Vascular; Humans | 2000 |
Aspirin for vascular dementia.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cognition Disorders; Dementia, Vascular; Humans; R | 2000 |
4 trials available for aspirin and Dementia, Vascular
| Article | Year |
|---|---|
Rationale for a trial of low-dose aspirin for the primary prevention of major adverse cardiovascular events and vascular dementia in the elderly: Aspirin in Reducing Events in the Elderly (ASPREE).
Topics: Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Dementia, Vascular; Double-Blind Method; | 2003 |
Rivastigmine superior to aspirin plus nimodipine in subcortical vascular dementia: an open, 16-month, comparative study.
Topics: Aged; Aged, 80 and over; Aspirin; Carbamates; Cholinesterase Inhibitors; Cognition Disorders; Dement | 2004 |
Volumetric measurement of multifocal brain lesions. Implications for treatment trials of vascular dementia and multiple sclerosis.
Topics: Aspirin; Brain; Brain Ischemia; Dementia, Vascular; Double-Blind Method; Female; Humans; Magnetic Re | 1996 |
Increased thromboxane biosynthesis is associated with poststroke dementia.
Topics: Aged; Aspirin; Biomarkers; Blood Platelets; Brain Ischemia; Cerebral Hemorrhage; Chronic Disease; Co | 1999 |
9 other studies available for aspirin and Dementia, Vascular
| Article | Year |
|---|---|
The quest for dementia prevention does not include an aspirin a day.
Topics: Aspirin; Cognitive Dysfunction; Dementia, Vascular; Humans | 2020 |
[Effect of AChE and BuChE inhibition by rivastigmin in a group of old-old elderly patients with cerebrovascular impairment (SIVD type)].
Topics: Acetylcholinesterase; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; But | 2014 |
Simple Neuropsychological Tests May Identify Participants in Whom Aspirin Use Is Associated With Lower Dementia Incidence: The Canadian Study of Health and Aging.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Aspirin; Canada; Cyclooxygenase Inhibitors; Demen | 2016 |
Fluid levels in the bleeding brain: a marker for coagulopathy and hematoma expansion.
Topics: Aged; Aphasia, Broca; Aspirin; Confusion; Dementia, Vascular; Humans; Intracranial Hemorrhages; Male | 2017 |
Does aspirin affect outcome in vascular dementia? A retrospective case-notes analysis.
Topics: Age of Onset; Aged; Aspirin; Dementia, Vascular; Female; Hospitalization; Humans; Male; Platelet Agg | 2003 |
Progress of leukoaraiosis is inhibited by correction of platelet hyper-aggregability.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Brain; Dementia, Va | 2005 |
Should aspirin be discontinued for diagnostic lumbar puncture?
Topics: Aspirin; Contraindications; Dementia, Vascular; Humans; Platelet Aggregation Inhibitors; Risk Assess | 2006 |
Stroke prevention.
Topics: Aged; Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Dementia, Vascular; Humans; Hypertens | 1995 |
Subcortical vascular dementia: survey of treatment patterns and research considerations.
Topics: Aspirin; Canada; Cerebral Cortex; Data Collection; Dementia, Vascular; Geriatrics; Humans; Neurology | 1998 |