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aspirin and Deficiency of Glucose-6-Phosphate Dehydrogenase

aspirin has been researched along with Deficiency of Glucose-6-Phosphate Dehydrogenase in 38 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"The use of aspirin, as part of a dual antiplatelet therapy regimen, is an established standard following coronary stenting in patients suffering from acute coronary syndrome (ACS)."8.95Aspirin safety in glucose-6-phosphate dehydrogenase deficiency patients with acute coronary syndrome undergoing percutaneous coronary intervention. ( Al Hout, AR; Feghaly, J; Mercieca Balbi, M, 2017)
"Patients with ischemic stroke receiving aspirin (100 mg/day) for three months were recruited for a multicenter, prospective, cohort study."8.02Safety and efficacy of low-dose aspirin in ischemic stroke patients with different G6PD conditions. ( Chen, Y; Deng, W; Huang, W; Jiang, H; Li, J; Liang, Z; Liu, Q; Ou, Z; Ouyang, F; Wu, Z; Xing, S; Zeng, J; Zhang, Y, 2021)
"In total, 279 patients (40 G6PD-deficient and 239 G6PD-normal) with acute ischemic stroke treated with aspirin 100 mg/day from a cohort study were examined."8.02Association between aspirin-induced hemoglobin decline and outcome after acute ischemic stroke in G6PD-deficient patients. ( Chen, Y; Deng, W; Huang, W; Li, J; Liang, Z; Ou, Z; Ouyang, F; Xing, S; Yu, J; Zeng, J; Zhang, Y, 2021)
"Aspirin is an important drug in acute coronary syndromes (ACS) and percutaneous coronary interventions (PCI)."7.81Antiplatelet and invasive treatment in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency and acute coronary syndrome. The safety of aspirin. ( Kafkas, NV; Liakos, CI; Mouzarou, AG, 2015)
"The use of aspirin, as part of a dual antiplatelet therapy regimen, is an established standard following coronary stenting in patients suffering from acute coronary syndrome (ACS)."4.95Aspirin safety in glucose-6-phosphate dehydrogenase deficiency patients with acute coronary syndrome undergoing percutaneous coronary intervention. ( Al Hout, AR; Feghaly, J; Mercieca Balbi, M, 2017)
"Patients with ischemic stroke receiving aspirin (100 mg/day) for three months were recruited for a multicenter, prospective, cohort study."4.02Safety and efficacy of low-dose aspirin in ischemic stroke patients with different G6PD conditions. ( Chen, Y; Deng, W; Huang, W; Jiang, H; Li, J; Liang, Z; Liu, Q; Ou, Z; Ouyang, F; Wu, Z; Xing, S; Zeng, J; Zhang, Y, 2021)
"In total, 279 patients (40 G6PD-deficient and 239 G6PD-normal) with acute ischemic stroke treated with aspirin 100 mg/day from a cohort study were examined."4.02Association between aspirin-induced hemoglobin decline and outcome after acute ischemic stroke in G6PD-deficient patients. ( Chen, Y; Deng, W; Huang, W; Li, J; Liang, Z; Ou, Z; Ouyang, F; Xing, S; Yu, J; Zeng, J; Zhang, Y, 2021)
"Aspirin is an important drug in acute coronary syndromes (ACS) and percutaneous coronary interventions (PCI)."3.81Antiplatelet and invasive treatment in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency and acute coronary syndrome. The safety of aspirin. ( Kafkas, NV; Liakos, CI; Mouzarou, AG, 2015)
"Forty-four patients with Mediterranean-type glucose-6-phosphate dehydrogenase (G-6-PD) deficiency receiving long-term, low-dose aspirin were monitored over three months for evidence of hemolysis."3.68Long-term, low-dose aspirin is safe in glucose-6-phosphate dehydrogenase deficiency. ( Shalev, O, 1991)
"Twenty hemolytic accidents due to G6PD deficiency in Algeria are reported: 13 cases of favism, 2 cases of neonatal jaundice, one drug accident (aspirin), 4 of unknown cause."3.65[Hemolytic anemia caused by glucose-6-phosphate dehydrogenase deficiency. Aprpos of 20 cases from 1969 to 1974]. ( Benabadji, M; Benamani, M; Benmoussa, M; Kaid, DA; Mérad, F; Messerschmitt, J, 1977)
"G6PD deficiency is typically asymptomatic and many CVD patients with this enzyme defect start to take long-term aspirin therapy without G6PD activity examination; however, no consensus on the safety of aspirin in this population has been reached."2.72Aspirin Therapy in Cardiovascular Disease with Glucose-6-Phosphate Dehydrogenase Deficiency, Safe or Not? ( Chen, C; Chen, J; Chen, Y; Jiang, Z; Li, J; Li, P; Liang, J; Ou, Z; Ouyang, F; Wei, J; Zeng, J, 2021)
"Eleven of these children developed acute renal insufficiency."1.28Drug-induced haemolysis and renal failure in children with glucose-6-phosphate dehydrogenase deficiency in Afghanistan. ( Choudhry, VP; Fazel, I; Ghafary, A; Ghani, R; Qureshi, MA; Zaher, M, 1990)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199027 (71.05)18.7374
1990's3 (7.89)18.2507
2000's0 (0.00)29.6817
2010's4 (10.53)24.3611
2020's4 (10.53)2.80

Authors

AuthorsStudies
Sanna, GD1
Deriu, S1
Uras, M1
Murgia, A1
Talanas, G1
Moccia, E1
Corda, G1
Mura, E1
Saba, PS1
Parodi, G1
Chen, Y3
Li, J3
Ou, Z3
Zhang, Y2
Liang, Z2
Deng, W2
Huang, W2
Wu, Z1
Jiang, H1
Liu, Q1
Ouyang, F3
Xing, S2
Zeng, J3
Liang, J1
Jiang, Z1
Chen, C1
Li, P1
Chen, J1
Wei, J1
Yu, J1
Feghaly, J1
Al Hout, AR1
Mercieca Balbi, M1
Amekoudi, EY1
Sabi, KA1
Noto Kadou Kaza, B1
Kafkas, NV1
Liakos, CI1
Mouzarou, AG1
Pappas, C1
Ntai, K1
Parissis, JT1
Anastasiou-Nana, M1
SZEINBERG, A1
KELLERMANN, J1
ADAM, A1
SHEBA, C1
RAMOT, B1
PRANKERD, TA1
HARLEY, JD1
Seeler, RA1
Luken, JA1
Colonna, P1
Pazzi, A1
Accardo, G1
Aleotti, A1
Saletti, G1
Ali, NA1
al-Naama, LM1
Khalid, LO1
Kaid, DA1
Benmoussa, M1
Mérad, F1
Benamani, M1
Benabadji, M1
Messerschmitt, J1
Serup, J1
Chan, TK1
Todd, D1
Tso, SC1
Glader, BE2
Phadke, MA1
Kate, SL1
Sainami, GS1
Mutalik, GS1
Phadke, MV1
Baxi, AJ1
Choudhry, VP1
Ghafary, A1
Zaher, M1
Qureshi, MA1
Fazel, I1
Ghani, R1
Shalev, O1
Meloni, T1
Forteleoni, G1
Ogana, A1
Franca, V1
Owa, JA1
Smirnov, AN1
Pochedly, C1
Ente, G1
Dube, B1
Chawla, SC1
Vaish, SK1
Somani, PN1
Srivastava, PK1
Onadeko, BO1
Bademosi, O1
Brown, CB1
McMillan, JM1
Bateman, CJ1
Cattell, WR1
Ahmed, I1
Olowe, O1
Kovalev, IuR1
Erman, LV1
George, JN1
Miller, DR1
Weed, RI1
Shahidi, NT2
Westring, DW2
Baumes, RM1
Pisciotta, AV1

Reviews

3 reviews available for aspirin and Deficiency of Glucose-6-Phosphate Dehydrogenase

ArticleYear
Aspirin Therapy in Cardiovascular Disease with Glucose-6-Phosphate Dehydrogenase Deficiency, Safe or Not?
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2021, Volume: 21, Issue:4

    Topics: Aspirin; Cardiovascular Diseases; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Hemolysis;

2021
Aspirin safety in glucose-6-phosphate dehydrogenase deficiency patients with acute coronary syndrome undergoing percutaneous coronary intervention.
    BMJ case reports, 2017, Oct-09, Volume: 2017

    Topics: Acute Coronary Syndrome; Aspirin; Female; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Huma

2017
Adverse hematologic effects of drugs.
    Pediatric clinics of North America, 1972, Volume: 19, Issue:4

    Topics: Anemia, Hemolytic; Anemia, Macrocytic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents

1972

Other Studies

35 other studies available for aspirin and Deficiency of Glucose-6-Phosphate Dehydrogenase

ArticleYear
Aspirin adherence in subjects with glucose-6-phosphate-dehydrogenase deficiency having an acute coronary syndrome.
    European heart journal. Cardiovascular pharmacotherapy, 2021, 05-23, Volume: 7, Issue:3

    Topics: Acute Coronary Syndrome; Aspirin; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase Deficiency; Hu

2021
Safety and efficacy of low-dose aspirin in ischemic stroke patients with different G6PD conditions.
    International journal of stroke : official journal of the International Stroke Society, 2021, Volume: 16, Issue:4

    Topics: Aspirin; Brain Ischemia; Cohort Studies; Drug Therapy, Combination; Glucosephosphate Dehydrogenase;

2021
Association between aspirin-induced hemoglobin decline and outcome after acute ischemic stroke in G6PD-deficient patients.
    CNS neuroscience & therapeutics, 2021, Volume: 27, Issue:10

    Topics: Aged; Anemia; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Endpoint Determinati

2021
[Profound anemia, hemoglobinuria ... where to stop in the etiological investigation?].
    Nephrologie & therapeutique, 2014, Volume: 10, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Anemia, Hemolytic; Aspirin; Blackwater Fever; Erythrocyte Transfusi

2014
Antiplatelet and invasive treatment in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency and acute coronary syndrome. The safety of aspirin.
    Journal of clinical pharmacy and therapeutics, 2015, Volume: 40, Issue:3

    Topics: Acute Coronary Syndrome; Adenosine; Aged; Aspirin; Drug Therapy, Combination; Drug-Eluting Stents; G

2015
Dual anti-platelet therapy in patients with G6PD deficiency after percutaneous coronary intervention.
    International journal of cardiology, 2013, May-10, Volume: 165, Issue:2

    Topics: Aged; Aspirin; Drug Therapy, Combination; Glucosephosphate Dehydrogenase Deficiency; Humans; Male; P

2013
Haemolytic jaundice following aspirin administration to a patient with a deficiency of glucose-6-phosphate dehydrogenase in erythrocytes.
    Acta haematologica, 1960, Volume: 23

    Topics: Anemia, Hemolytic; Aspirin; Erythrocytes; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydroge

1960
ENZYMES AND DRUG SENSITIVITY. GLUCOSE 6-PHOSPHATE DEHYDROGENASE DEFICIENCY.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Acetanilides; Aminopyrine; Aminosalicylic Acid; Aminosalicylic Acids; Anemia, Hemolytic; Antimalaria

1964
GROSS CONGENITAL MALFORMATIONS IN SIBLINGS OF CHILDREN WITH GLUCOSE-6-PHOSPHATE DEHYDROGENASE-DEFICIENT ERYTHROCYTES.
    Australasian annals of medicine, 1964, Volume: 13

    Topics: Abnormalities, Drug-Induced; Aspirin; Congenital Abnormalities; Erythrocytes; Glucosephosphate Dehyd

1964
Hemolysis in ARF in a G6PD-deficient patient: case 2.
    Pediatric cardiology, 1984, Volume: 5, Issue:4

    Topics: Aspirin; Child; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Male; Rheumatic Fever

1984
Aspirin and glucose-6-phosphate dehydrogenase deficiency.
    British medical journal (Clinical research ed.), 1981, Oct-31, Volume: 283, Issue:6300

    Topics: Aspirin; Child; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Male

1981
[Scanning electron microscopic study of the morphological changes induced by acetylsalicylic acid in therapeutic doses in the red blood cells of a patient with a very severe G6PD deficiency and clinical manifestations of favism].
    Giornale di clinica medica, 1980, Volume: 61, Issue:6

    Topics: Aspirin; Erythrocytes; Favism; Glucosephosphate Dehydrogenase Deficiency; Humans; In Vitro Technique

1980
Haemolytic potential of three chemotherapeutic agents and aspirin in glucose-6-phosphate dehydrogenase deficiency.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 1999, Volume: 5, Issue:3

    Topics: Anti-Bacterial Agents; Antimalarials; Aspirin; Case-Control Studies; Chloramphenicol; Drug Evaluatio

1999
[Hemolytic anemia caused by glucose-6-phosphate dehydrogenase deficiency. Aprpos of 20 cases from 1969 to 1974].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1977, Apr-23, Volume: 53, Issue:16

    Topics: Adolescent; Anemia, Hemolytic; Aspirin; Child; Child, Preschool; Favism; Glucosephosphate Dehydrogen

1977
[Erythrocyte glucose-6-phosphate dehydrogenase deficiency. Review and report of a case].
    Ugeskrift for laeger, 1977, Oct-31, Volume: 139, Issue:44

    Topics: Adult; Anemia, Hemolytic; Antipyrine; Aspirin; Erythrocytes; Glucosephosphate Dehydrogenase; Glucose

1977
Drug-induced haemolysis in glucose-6-phosphate dehydrogenase deficiency.
    British medical journal, 1976, Nov-20, Volume: 2, Issue:6046

    Topics: Aspirin; Cell Survival; China; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Male; N

1976
Evaluation of the hemolytic role of aspirin in glucose-6-phosphate dehydrogenase deficiency.
    The Journal of pediatrics, 1976, Volume: 89, Issue:6

    Topics: Aspirin; Bilirubin; Child; Erythrocytes; Female; Gentisates; Glucosephosphate Dehydrogenase Deficien

1976
Hyperhaemolytic and vascular occlusive crises in sickle cell disease. A case report with brief review of literature.
    The Journal of the Association of Physicians of India, 1975, Volume: 23, Issue:1

    Topics: Anemia, Hemolytic; Anemia, Sickle Cell; Aspirin; Child; Glucosephosphate Dehydrogenase Deficiency; H

1975
Salicylate-induced injury of pyruvate-kinase-deficient erythrocytes.
    The New England journal of medicine, 1976, Apr-22, Volume: 294, Issue:17

    Topics: Adenosine Triphosphate; Anemia, Hemolytic; Aspirin; Erythrocytes; Glucose; Glucosephosphate Dehydrog

1976
Drug-induced haemolysis and renal failure in children with glucose-6-phosphate dehydrogenase deficiency in Afghanistan.
    Annals of tropical paediatrics, 1990, Volume: 10, Issue:4

    Topics: Acute Kidney Injury; Adolescent; Afghanistan; Antimalarials; Aspirin; Child; Child, Preschool; Chlor

1990
Long-term, low-dose aspirin is safe in glucose-6-phosphate dehydrogenase deficiency.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:10

    Topics: Adult; Aspirin; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Male; Middle Aged; Saf

1991
Aspirin-induced acute haemolytic anaemia in glucose-6-phosphate dehydrogenase-deficient children with systemic arthritis.
    Acta haematologica, 1989, Volume: 81, Issue:4

    Topics: Anemia, Hemolytic; Arthritis; Aspirin; Child, Preschool; Glucosephosphate Dehydrogenase Deficiency;

1989
Relationship between exposure to icterogenic agents, glucose-6-phosphate dehydrogenase deficiency and neonatal jaundice in Nigeria.
    Acta paediatrica Scandinavica, 1989, Volume: 78, Issue:6

    Topics: Aspirin; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Infant; Infant, Newborn; Jaundic

1989
[Acute drug-induced hemolytic anemia].
    Fel'dsher i akusherka, 1989, Volume: 54, Issue:10

    Topics: Acute Disease; Adult; Anemia, Hemolytic; Aspirin; Diagnosis, Differential; Female; Glucosephosphate

1989
Consumption coagulopathy following haemolytic crisis in glucose-6-phosphate dehydrogenase deficient subjects.
    The Journal of the Association of Physicians of India, 1972, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Aspirin; Disseminated Intravascular Coagulation; Glucosephosphate Dehydrogenase D

1972
Glucose-6-phosphate dehydrogenase deficiency and intravascular haemolysis.
    Irish journal of medical science, 1974, Volume: 143, Issue:4

    Topics: Adolescent; Adult; Anemia, Hemolytic; Aspirin; Dapsone; Female; Glucosephosphate Dehydrogenase Defic

1974
Acute renal failure following analgesic overdose in G6PD deficiency.
    British journal of urology, 1972, Volume: 44, Issue:2

    Topics: Acute Disease; Acute Kidney Injury; Adult; Anemia, Hemolytic; Anemia, Sideroblastic; Aspirin; Biopsy

1972
Haemoglobinuria in Nigerian children.
    The African journal of medical sciences, 1971, Volume: 2, Issue:2

    Topics: Acetaminophen; Aspirin; Autopsy; Brain; Caffeine; Child; Child, Preschool; Coombs Test; Diagnosis, D

1971
[Genesis of drug-induced hemolytic jaundice].
    Voprosy okhrany materinstva i detstva, 1971, Volume: 16, Issue:6

    Topics: Adolescent; Aminopyrine; Anemia, Hemolytic; Aspirin; Child; Female; Glucosephosphate Dehydrogenase;

1971
Heinz body hemolytic anemias.
    New York state journal of medicine, 1970, Oct-15, Volume: 70, Issue:20

    Topics: Anemia, Hemolytic; Aspirin; Child; Female; Glucosephosphate Dehydrogenase Deficiency; Heinz Bodies;

1970
Acetylsalicylic acid--induced hemolysis and its mechanism.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:7

    Topics: Adolescent; Anemia, Hemolytic; Aspirin; Child; Erythrocyte Aging; Erythrocytes; Gentisates; Glucosep

1970
[Blood donors. Importance of systematic detection of GPD (glucosephosphate-6-dehydrogenase) deficiency].
    Maroc medical, 1970, Volume: 50, Issue:541

    Topics: Ascorbic Acid; Aspirin; Blood Donors; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans;

1970
Drug-induced hemolysis: biochemical considerations.
    Birth defects original article series, 1970, Volume: 6, Issue:2

    Topics: Acetanilides; Anemia, Hemolytic; Aspirin; Biotransformation; Erythrocytes; Glucosephosphate Dehydrog

1970
Hemolytic anemia complicating viral hepatitis and G-6-PD deficiency.
    JAMA, 1969, Jun-30, Volume: 208, Issue:13

    Topics: Anemia, Hemolytic; Anemia, Hemolytic, Congenital; Aspirin; Glucosephosphate Dehydrogenase Deficiency

1969
Anemia, cataracts, and seizures in patient with glucose-6-phosphate dehydrogenase deficiency.
    Archives of internal medicine, 1966, Volume: 118, Issue:4

    Topics: Anemia, Hemolytic, Congenital Nonspherocytic; Aspirin; Cataract; Chromium Isotopes; Electrophoresis;

1966