aspirin has been researched along with Debility in 8 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic inflammation may lead to frailty, however the potential for anti-inflammatory medications such as aspirin to prevent frailty is unknown." | 5.41 | Association Between Long-Term Aspirin Use and Frailty in Men: The Physicians' Health Study. ( Djousse, L; Driver, JA; Dufour, AB; Gaziano, JM; Orkaby, AR; Sesso, HD; Travison, TG; Yang, L, 2021) |
| "Frailty is associated with chronic inflammation, which may be modified by aspirin." | 3.11 | The Effect of Low-Dose Aspirin on Frailty Phenotype and Frailty Index in Community-Dwelling Older Adults in the ASPirin in Reducing Events in the Elderly Study. ( Chan, A; Ekram, ARMS; Ernst, ME; Espinoza, SE; Fitzgerald, SM; Lockery, JE; McNeil, JJ; Murray, AM; Nelson, MR; Newman, AB; Orchard, SG; Polekhina, G; Reid, CM; Ryan, J; Shah, RC; Stocks, NP; Storey, E; Trevaks, R; Ward, SA; Wolfe, R; Woods, RL, 2022) |
| "Frailty is a state of heightened vulnerability and susceptibility to physiologic stressors that increases with age." | 3.11 | Validation of a Deficit-Accumulation Frailty Index in the ASPirin in Reducing Events in the Elderly Study and Its Predictive Capacity for Disability-Free Survival. ( Beilin, LJ; Ekram, ARMS; Ernst, ME; Espinoza, S; Fitzgerald, S; McNeil, JJ; Murray, AM; Newman, AB; Orchard, SG; Ryan, J; Shah, RC; Ward, SA; Williamson, JD; Wolfe, R; Woods, RL, 2022) |
| "Frailty and sarcopenia have been extensively studied in heart failure (HF) patients, but their coexistence is unknown." | 1.91 | Associations of medicine use and ejection fraction with the coexistence of frailty and sarcopenia in a sample of heart failure outpatients: a cross-sectional study. ( Aguiar, MJV; Amaral, TF; Azevedo, LF; Borges, N; Fernandes, L; Fernandes, M; Martins, S; Moreira, E; Silva-Cardoso, J; Sousa-Santos, AR; Valdiviesso, R, 2023) |
| "In multivariable Cox frailty regression, the adjusted risk of any adverse event through the 45-day follow-up visit were significantly lower for discharge on warfarin alone (HR: 0." | 1.72 | Antithrombotic Therapy After Left Atrial Appendage Occlusion in Patients With Atrial Fibrillation. ( Curtis, JP; Daimee, UA; Doshi, SK; Du, C; Freeman, JV; Friedman, DJ; Gibson, D; Goldsweig, AM; Higgins, AY; Masoudi, FA; Minges, KE; Pereira, L; Price, MJ; Reddy, VY; Varosy, PD; Wang, Y, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 8 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Espinoza, SE | 1 |
| Woods, RL | 3 |
| Ekram, ARMS | 2 |
| Ernst, ME | 3 |
| Polekhina, G | 1 |
| Wolfe, R | 3 |
| Shah, RC | 2 |
| Ward, SA | 2 |
| Storey, E | 1 |
| Nelson, MR | 1 |
| Reid, CM | 1 |
| Lockery, JE | 1 |
| Orchard, SG | 2 |
| Trevaks, R | 1 |
| Fitzgerald, SM | 1 |
| Stocks, NP | 1 |
| Chan, A | 1 |
| McNeil, JJ | 3 |
| Murray, AM | 2 |
| Newman, AB | 2 |
| Ryan, J | 3 |
| Montgomery, S | 1 |
| Miedema, MD | 1 |
| Dodson, JA | 1 |
| Freeman, JV | 1 |
| Higgins, AY | 1 |
| Wang, Y | 1 |
| Du, C | 1 |
| Friedman, DJ | 1 |
| Daimee, UA | 1 |
| Minges, KE | 1 |
| Pereira, L | 1 |
| Goldsweig, AM | 1 |
| Price, MJ | 1 |
| Reddy, VY | 1 |
| Gibson, D | 1 |
| Doshi, SK | 1 |
| Varosy, PD | 1 |
| Masoudi, FA | 1 |
| Curtis, JP | 2 |
| Walker, RG | 1 |
| Bongetti, E | 1 |
| Polkinghorne, KR | 1 |
| Espinoza, S | 2 |
| Murray, A | 1 |
| Faridi, KF | 1 |
| Strom, JB | 1 |
| Kundi, H | 1 |
| Butala, NM | 1 |
| Gao, Q | 1 |
| Song, Y | 1 |
| Zheng, L | 1 |
| Tamez, H | 1 |
| Shen, C | 1 |
| Secemsky, EA | 1 |
| Yeh, RW | 1 |
| Valdiviesso, R | 1 |
| Amaral, TF | 1 |
| Moreira, E | 1 |
| Sousa-Santos, AR | 1 |
| Fernandes, M | 1 |
| Aguiar, MJV | 1 |
| Martins, S | 1 |
| Azevedo, LF | 1 |
| Fernandes, L | 1 |
| Silva-Cardoso, J | 1 |
| Borges, N | 1 |
| Orkaby, AR | 1 |
| Yang, L | 1 |
| Dufour, AB | 1 |
| Travison, TG | 1 |
| Sesso, HD | 1 |
| Driver, JA | 1 |
| Djousse, L | 1 |
| Gaziano, JM | 1 |
| Fitzgerald, S | 1 |
| Beilin, LJ | 1 |
| Williamson, JD | 1 |
1 review available for aspirin and Debility
| Article | Year |
|---|---|
Aspirin and statin therapy for primary prevention of cardiovascular disease in older adults.
Topics: Aged; Aspirin; Cardiovascular Diseases; Frailty; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibit | 2022 |
4 trials available for aspirin and Debility
| Article | Year |
|---|---|
The Effect of Low-Dose Aspirin on Frailty Phenotype and Frailty Index in Community-Dwelling Older Adults in the ASPirin in Reducing Events in the Elderly Study.
Topics: Aged; Aspirin; Disabled Persons; Frail Elderly; Frailty; Humans; Independent Living; Phenotype; Unit | 2022 |
Association Between Claims-Defined Frailty and Outcomes Following 30 Versus 12 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention: Findings From the EXTEND-DAPT Study.
Topics: Aged; Aspirin; Child, Preschool; Drug Therapy, Combination; Frailty; Hemorrhage; Humans; Medicare; P | 2023 |
Association Between Long-Term Aspirin Use and Frailty in Men: The Physicians' Health Study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Frailty; Humans; Inflamma | 2021 |
Validation of a Deficit-Accumulation Frailty Index in the ASPirin in Reducing Events in the Elderly Study and Its Predictive Capacity for Disability-Free Survival.
Topics: Aged; Aged, 80 and over; Aspirin; Dementia; Disabled Persons; Female; Frail Elderly; Frailty; Geriat | 2022 |
3 other studies available for aspirin and Debility
| Article | Year |
|---|---|
Antithrombotic Therapy After Left Atrial Appendage Occlusion in Patients With Atrial Fibrillation.
Topics: Anticoagulants; Aspirin; Atrial Appendage; Atrial Fibrillation; Fibrinolytic Agents; Frailty; Humans | 2022 |
The association of frailty with chronic kidney disease in older adults using the ASPirin in reducing events in the elderly cohort.
Topics: Aged; Albuminuria; Aspirin; Cross-Sectional Studies; Frailty; Glomerular Filtration Rate; Humans; Re | 2023 |
Associations of medicine use and ejection fraction with the coexistence of frailty and sarcopenia in a sample of heart failure outpatients: a cross-sectional study.
Topics: Aged; Anticoagulants; Antidepressive Agents; Aspirin; Cross-Sectional Studies; Female; Frailty; Hear | 2023 |