Page last updated: 2024-10-23

aspirin and Deafness

aspirin has been researched along with Deafness in 24 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Deafness: A general term for the complete loss of the ability to hear from both ears.

Research Excerpts

ExcerptRelevanceReference
" Almost half of the patients taking aspirin were unable to tolerate the drug in adequate dosage for six months."6.64Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin. ( Balme, HW; Berry, H; Hart, FD; Huskisson, EC; Scott, J; Wojtulewski, JA, 1974)
" Known side effects of aspirin-tinnitus, deafness, and gastrointestinal disturbance-were more efficiently shown and symptoms not included in the check list were more likely to be reported when a check list was not used."5.04Measurement of side effects of drugs. ( Huskisson, EC; Wojtulewski, JA, 1974)
" Almost half of the patients taking aspirin were unable to tolerate the drug in adequate dosage for six months."2.64Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin. ( Balme, HW; Berry, H; Hart, FD; Huskisson, EC; Scott, J; Wojtulewski, JA, 1974)
"Susac's syndrome is an extremely rare clinical manifestation characterized by the triad of fluctuating sensorineural hearing loss, sudden visual loss and encephalopathy."2.41[Susac syndrome as a cause of sensorineural hearing loss]. ( Albaladejo Devis, I; Cubillana Herrero, JD; Jiménez Cervantes-Nicolás, JA; Minguez Merlos, N; Rodríguez González-Herrero, B; Soler Valcárcel, A, 2002)
"Aspirin ototoxicity has been studied on guinea pigs by shiver-audiometry and histological investigation of the cochlear duct."1.25Aspirin ototoxicity in the guinea pig. ( Crifò, S, 1975)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199022 (91.67)18.7374
1990's0 (0.00)18.2507
2000's2 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cubillana Herrero, JD1
Soler Valcárcel, A1
Albaladejo Devis, I1
Rodríguez González-Herrero, B1
Minguez Merlos, N1
Jiménez Cervantes-Nicolás, JA1
KAPUR, YP1
MCCABE, PA1
DEY, FL1
Murakami, T1
Nakayasu, H1
Doi, M1
Fukada, Y1
Hayashi, M1
Suzuki, T1
Takeuchi, Y1
Nakashima, K1
Tugwell, P1
Hart, L1
Kraag, G1
Park, A1
Dok, C1
Bianchi, F1
Goldsmith, C1
Buchanan, WW1
Johnsen, NJ1
Elberling, C1
Porter, J1
Jick, H1
Mukherjee, DK1
Mukherjee, K1
Miller, RR1
Crifò, S3
Di Feliciantonio, D1
Di Francesco, G2
Sidoli, A2
Wright, R1
Difeliciantonio, D1
Falò, S1
Jongkees, LB1
Huskisson, EC2
Wojtulewski, JA2
Berry, H1
Scott, J1
Hart, FD1
Balme, HW1
Horton, EW1
Jones, RL1
Marr, CG1
Diem, E1
Fritsch, P1
Pomare, EW1
Treadwell, BL1
Myers, EN1
Bernstein, JM1
Fisch, L1
Poulsen, J1
Jarvis, JF1
Gignoux, M1
Martin, H1
Cajgfinger, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of a Cold Water Immersion (CWI) on Pain in People With Gouty Arthritis: A Community Based Randomized Controlled Trial[NCT04587544]76 participants (Actual)Interventional2019-07-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aspirin and Deafness

ArticleYear
[Susac syndrome as a cause of sensorineural hearing loss].
    Acta otorrinolaringologica espanola, 2002, Volume: 53, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Aspirin; Cerebral Infarction; Cochlea; Combined Modality Therapy; D

2002

Trials

3 trials available for aspirin and Deafness

ArticleYear
Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin.
    British medical journal, 1974, Feb-02, Volume: 1, Issue:5900

    Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Body Temperature; Clinical Trials as Topic; Deafness;

1974
Measurement of side effects of drugs.
    British medical journal, 1974, Jun-29, Volume: 2, Issue:5921

    Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Deafness; Drug-Related Side Effects and Adverse React

1974
Sustained release aspirin.
    The New Zealand medical journal, 1971, Volume: 73, Issue:466

    Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Deafness; Delayed-Action Preparations; Female; Human

1971

Other Studies

20 other studies available for aspirin and Deafness

ArticleYear
OTOTOXICITY OF ACETYLSALICYLIC ACID.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1965, Volume: 81

    Topics: Adolescent; Aspirin; Audiometry; Deafness; Diagnosis, Differential; Drug Hypersensitivity; Humans; L

1965
THE EFFECT OF ASPIRIN UPON AUDITORY SENSITIVITY.
    The Annals of otology, rhinology, and laryngology, 1965, Volume: 74

    Topics: Aspirin; Audiometry; Cochlea; Deafness; Hearing Tests; Humans; Pharmacology; Tinnitus; Toxicology

1965
Anterior and posterior inferior cerebellar artery infarction with sudden deafness and vertigo.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2006, Volume: 13, Issue:10

    Topics: Acute Disease; Antipyrine; Aspirin; Basilar Artery; Brain Infarction; Cerebellar Diseases; Cerebellu

2006
Controlled trial of clinical utility of serum salicylate monitoring in rheumatoid arthritis.
    The Journal of rheumatology, 1984, Volume: 11, Issue:4

    Topics: Arthritis, Rheumatoid; Aspirin; Deafness; Double-Blind Method; Drug Administration Schedule; Evaluat

1984
Evoked acoustic emissions from the human ear. I. Equipment and response parameters.
    Scandinavian audiology, 1982, Volume: 11, Issue:1

    Topics: Acoustic Stimulation; Adult; Aspirin; Auditory Threshold; Cochlea; Deafness; Ear; Ear Canal; Evoked

1982
Drug-induced anaphylaxis, convulsions, deafness, and extrapyramidal symptoms.
    Lancet (London, England), 1977, Mar-12, Volume: 1, Issue:8011

    Topics: Anaphylaxis; Anti-Bacterial Agents; Aspirin; Basal Ganglia Diseases; Deafness; Drug-Related Side Eff

1977
Ototoxicity of commonly used pharmaceutical preparations.
    Nigerian medical journal : journal of the Nigeria Medical Association, 1979, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Ampicillin; Antihypertensive Agents; Antineoplastic Agents; Aspirin; Child; Chlor

1979
Deafness due to plain and long-acting aspirin tablets.
    Journal of clinical pharmacology, 1978, Volume: 18, Issue:10

    Topics: Aged; Aspirin; Deafness; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Salicylates

1978
Aspirin ototoxicity in the guinea pig.
    ORL; journal for oto-rhino-laryngology and its related specialties, 1975, Volume: 37, Issue:1

    Topics: Animals; Aspirin; Audiometry; Deafness; Differential Threshold; Dose-Response Relationship, Drug; Ea

1975
[Research on the chronic audio-toxicity of aspirin in the guinea pig].
    Bollettino della Societa italiana di biologia sperimentale, 1974, Feb-15, Volume: 50, Issue:3

    Topics: Animals; Aspirin; Audiometry; Chronic Disease; Deafness; Ear; Guinea Pigs; Hearing; Labyrinth Diseas

1974
[Research on the acute audio-toxicity of aspirin in the guinea pig].
    Bollettino della Societa italiana di biologia sperimentale, 1974, Feb-15, Volume: 50, Issue:3

    Topics: Animals; Aspirin; Audiometry; Cochlea; Cochlear Nerve; Deafness; Ear; Ear, Inner; Guinea Pigs; Heari

1974
[Deafness as a result of the use of drugs].
    Nederlands tijdschrift voor geneeskunde, 1974, Nov-02, Volume: 118, Issue:44

    Topics: Anti-Bacterial Agents; Aspirin; Deafness; Drug-Related Side Effects and Adverse Reactions; Ethacryni

1974
Effects of aspirin on prostaglandin and fructose levels in human semen.
    Journal of reproduction and fertility, 1973, Volume: 33, Issue:3

    Topics: Adult; Aspirin; Deafness; Factor Analysis, Statistical; Fructose; Humans; Male; Nausea; Prostaglandi

1973
Drug-induced deafness.
    JAMA, 1973, Apr-23, Volume: 224, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Aspirin; Deafness; Drug-Related Side Effects and Adverse Reactions; Et

1973
[Salicylate poisoning by percutaneous resorption].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1973, Volume: 24, Issue:12

    Topics: Administration, Topical; Aspirin; Deafness; Epistaxis; Female; Hallucinations; Headache; Humans; Poi

1973
Salicylate ototoxicity; a clinical and experimental study.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1965, Volume: 82, Issue:5

    Topics: Adolescent; Adult; Aged; Animals; Arthritis, Rheumatoid; Aspirin; Audiometry; Cochlea; Deafness; Hap

1965
The selective and differential vulnerability of the auditory system. In: Sensorineural hearing loss.
    Ciba Foundation symposium, 1970

    Topics: Aspirin; Auditory Pathways; Central Nervous System; Cochlea; Deafness; Diseases in Twins; Ear; Facia

1970
[Ototoxic effect of readily soluble acetylsalicylic acid].
    Ugeskrift for laeger, 1970, Dec-17, Volume: 132, Issue:51

    Topics: Adolescent; Adult; Aspirin; Audiometry; Child; Deafness; Female; Humans; Male; Time Factors

1970
A case of unilateral permanent deafness following acetylsalicylic acid.
    The Journal of laryngology and otology, 1966, Volume: 80, Issue:3

    Topics: Adult; Aspirin; Audiometry; Deafness; Female; Humans

1966
[Cochleo-vestibular complications after attempted suicide with aspirin].
    Journal francais d'oto-rhino-laryngologie et chirurgie maxillo-faciale, 1966, Volume: 15, Issue:6

    Topics: Adolescent; Aspirin; Deafness; Female; Humans; Labyrinth Diseases; Suicide

1966