aspirin has been researched along with Deafness, Transitory in 28 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A sudden hearing loss in a woman on aspirin has uncovered a frequently neglected toxicological parameter." | 7.75 | Hearing loss in a woman on aspirin: the silent pharmacokinetic parameter. ( Koren, G, 2009) |
| "Several authors have investigated the interaction of noise and aspirin in hearing loss, with conflicting results." | 7.67 | Combined effects of aspirin and noise in causing permanent hearing loss. ( Anderson, T; Carson, SS; Prazma, J; Pulver, SH, 1989) |
| " A statistically significant increase in the threshold for 2 kHz was found 1 to 72 hr after dosing but not for 4, 8 and 10 kHz." | 5.30 | Frequency selectivity on aspirin-induced hearing loss in rats with auditory stimulus-induced conditioned suppression. ( Kurata, K; Nishida, N; Sato, S; Suzuki, T; Tokuriki, M; Tsukuda, R, 1997) |
| "Aspirin is known to produce a reversible loss of hearing that can be as great as 40 dB, depending upon the dose and the individual subject." | 5.27 | Aspirin can potentiate the temporary hearing loss induced by intense sounds. ( McFadden, D; Plattsmier, HS, 1983) |
| " Hearing loss was associated with valproic acid and low-dose acetylsalicylic acid exposure during pregnancy." | 3.88 | In utero drug exposure and hearing impairment in 2-year-old children A case-control study using the EFEMERIS database. ( Araujo, M; Benevent, J; Damase-Michel, C; Durrieu, G; Foch, C; Lacroix, I; Montastruc, JL; Weckel, A, 2018) |
| " Aspirin (salicylate) ototoxicity can cause reversible hearing loss and reduces otoacoustic emission generation in the cochlea." | 3.77 | Effects of aspirin on distortion product fine structure: interpreted by the two-source model for distortion product otoacoustic emissions generation. ( Long, GR; Rao, A, 2011) |
| "A sudden hearing loss in a woman on aspirin has uncovered a frequently neglected toxicological parameter." | 3.75 | Hearing loss in a woman on aspirin: the silent pharmacokinetic parameter. ( Koren, G, 2009) |
| " The patient had been treated for chronic heart failure and prescribed 100 mg/day of acetylsalicylic acid (aspirin) for its antiplatelet effect." | 3.75 | Detection of presumed hemorrhage in the ampullar endolymph of the semicircular canal: a case report. ( Ishihara, S; Iwano, S; Naganawa, S; Nakashima, T; Sone, M, 2009) |
| "Several authors have investigated the interaction of noise and aspirin in hearing loss, with conflicting results." | 3.67 | Combined effects of aspirin and noise in causing permanent hearing loss. ( Anderson, T; Carson, SS; Prazma, J; Pulver, SH, 1989) |
| "Aspirin has been shown to minimise gentamicin-induced ototoxicity." | 2.84 | COAST (Cisplatin ototoxicity attenuated by aspirin trial): A phase II double-blind, randomised controlled trial to establish if aspirin reduces cisplatin induced hearing-loss. ( Abab, J; Bayne, M; Chester, J; Crabb, SJ; Davies, J; Ellis, M; Galanopoulou, A; Geldart, T; Hartley, A; Huddart, R; Joffe, JK; King, E; Lamb, C; Lineton, B; Maishman, T; Martin, K; Moody, R; Nutting, C; Ottensmeier, C; Popat, S; Ratcliffe, I; Stanton, L; Thomas, G; Thornton, R, 2017) |
| "This article reviews recent advances in the protection from the adverse auditory or vestibular side effects associated with antibacterial treatment with aminoglycoside antibiotics." | 2.44 | Aspirin attenuates gentamicin ototoxicity: from the laboratory to the clinic. ( Chen, Y; Huang, WG; Qiu, JH; Schacht, J; Sha, SH; Wang, JL; Zha, DJ, 2007) |
| " Among the documented adverse effects of aspirin is the potential for ototoxicity." | 2.38 | Ototoxicity associated with salicylates. A brief review. ( Brien, JA, 1993) |
| " A statistically significant increase in the threshold for 2 kHz was found 1 to 72 hr after dosing but not for 4, 8 and 10 kHz." | 1.30 | Frequency selectivity on aspirin-induced hearing loss in rats with auditory stimulus-induced conditioned suppression. ( Kurata, K; Nishida, N; Sato, S; Suzuki, T; Tokuriki, M; Tsukuda, R, 1997) |
| "Aspirin is known to produce a reversible loss of hearing that can be as great as 40 dB, depending upon the dose and the individual subject." | 1.27 | Aspirin can potentiate the temporary hearing loss induced by intense sounds. ( McFadden, D; Plattsmier, HS, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (14.29) | 18.7374 |
| 1990's | 2 (7.14) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 12 (42.86) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Sheng, Y | 1 |
| Yang, C | 1 |
| Curhan, S | 1 |
| Curhan, G | 1 |
| Wang, M | 2 |
| Crabb, SJ | 1 |
| Martin, K | 1 |
| Abab, J | 1 |
| Ratcliffe, I | 1 |
| Thornton, R | 1 |
| Lineton, B | 1 |
| Ellis, M | 1 |
| Moody, R | 1 |
| Stanton, L | 1 |
| Galanopoulou, A | 1 |
| Maishman, T | 1 |
| Geldart, T | 1 |
| Bayne, M | 1 |
| Davies, J | 1 |
| Lamb, C | 1 |
| Popat, S | 1 |
| Joffe, JK | 1 |
| Nutting, C | 1 |
| Chester, J | 1 |
| Hartley, A | 1 |
| Thomas, G | 1 |
| Ottensmeier, C | 1 |
| Huddart, R | 1 |
| King, E | 1 |
| Foch, C | 1 |
| Araujo, M | 1 |
| Weckel, A | 1 |
| Damase-Michel, C | 1 |
| Montastruc, JL | 1 |
| Benevent, J | 1 |
| Durrieu, G | 1 |
| Lacroix, I | 1 |
| Cuffel, C | 1 |
| Guyot, JP | 1 |
| Blake, DM | 1 |
| Vazquez, A | 1 |
| Tomovic, S | 1 |
| Jyung, RW | 1 |
| Kandathil, CK | 1 |
| Cunnane, ME | 1 |
| McKenna, MJ | 1 |
| Curtin, HD | 1 |
| Stankovic, KM | 2 |
| Lin, BM | 1 |
| Curhan, SG | 2 |
| Eavey, R | 2 |
| Curhan, GC | 2 |
| Koren, G | 1 |
| Behnoud, F | 2 |
| Davoudpur, K | 1 |
| Goodarzi, MT | 1 |
| Dörr, J | 1 |
| Radbruch, H | 1 |
| Bock, M | 1 |
| Wuerfel, J | 1 |
| Brüggemann, A | 1 |
| Wandinger, KP | 1 |
| Zeise, D | 1 |
| Pfueller, CF | 1 |
| Zipp, F | 1 |
| Paul, F | 1 |
| Naganawa, S | 1 |
| Ishihara, S | 1 |
| Iwano, S | 1 |
| Sone, M | 1 |
| Nakashima, T | 1 |
| Komaroff, AL | 1 |
| Naeem, M | 1 |
| Rahimnajjad, NA | 1 |
| Rao, A | 1 |
| Long, GR | 1 |
| Leschziner, G | 1 |
| Connor, S | 1 |
| Wroe, SJ | 1 |
| Ferner, RE | 1 |
| Shargorodsky, J | 1 |
| Usami, S | 1 |
| Wecker, H | 1 |
| Laubert, A | 1 |
| Parazzini, M | 1 |
| Hall, AJ | 1 |
| Lutman, ME | 1 |
| Kapadia, S | 1 |
| Sha, SH | 2 |
| Qiu, JH | 2 |
| Schacht, J | 2 |
| Chen, Y | 1 |
| Huang, WG | 1 |
| Zha, DJ | 1 |
| Wang, JL | 1 |
| Kleffner, I | 1 |
| Ringelstein, EB | 1 |
| Stupp, N | 1 |
| Niederstadt, TU | 1 |
| Young, P | 1 |
| McFadden, D | 2 |
| Plattsmier, HS | 2 |
| Pasanen, EG | 1 |
| Brien, JA | 1 |
| Kurata, K | 1 |
| Nishida, N | 1 |
| Tsukuda, R | 1 |
| Suzuki, T | 1 |
| Sato, S | 1 |
| Tokuriki, M | 1 |
| Oudot, J | 1 |
| Pignat, JC | 1 |
| Martin, H | 1 |
| Carson, SS | 1 |
| Prazma, J | 1 |
| Pulver, SH | 1 |
| Anderson, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Investigation of Relevant Biomarkers in Patients With Susac Syndrome[NCT01273792] | 30 participants (Anticipated) | Observational | 2010-05-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for aspirin and Deafness, Transitory
| Article | Year |
|---|---|
Aspirin attenuates gentamicin ototoxicity: from the laboratory to the clinic.
Topics: Animals; Anti-Bacterial Agents; Aspirin; Cochlea; Gentamicins; Hearing Loss; Humans; Randomized Cont | 2007 |
Ototoxicity associated with salicylates. A brief review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Hearing Loss; Humans; Salicylates; Tinnitus | 1993 |
3 trials available for aspirin and Deafness, Transitory
| Article | Year |
|---|---|
COAST (Cisplatin ototoxicity attenuated by aspirin trial): A phase II double-blind, randomised controlled trial to establish if aspirin reduces cisplatin induced hearing-loss.
Topics: Adult; Aged; Antineoplastic Agents; Aspirin; Audiometry, Pure-Tone; Cisplatin; Cytoprotection; Doubl | 2017 |
Can aspirin protect or at least attenuate gentamicin ototoxicity in humans?
Topics: Anti-Bacterial Agents; Aspirin; Double-Blind Method; Female; Gentamicins; Hearing Loss; Humans; Male | 2009 |
Aspirin to prevent gentamicin-induced hearing loss.
Topics: Adult; Anti-Bacterial Agents; Antioxidants; Aspirin; Cyclooxygenase Inhibitors; Double-Blind Method; | 2006 |
23 other studies available for aspirin and Deafness, Transitory
| Article | Year |
|---|---|
Analytical methods for correlated data arising from multicenter hearing studies.
Topics: Aspirin; Hearing; Hearing Loss; Humans | 2022 |
In utero drug exposure and hearing impairment in 2-year-old children A case-control study using the EFEMERIS database.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Case-Control Studies; Child, Pres | 2018 |
[Aspirin ototoxicity: a rare situation today].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Overdose; Ear, Inner; Female; Hearing Loss; H | 2013 |
Otologic manifestation of Samter triad.
Topics: Aspirin; Asthma, Aspirin-Induced; Female; Hearing Loss; Humans; Middle Aged; Nasal Polyps; Otitis Me | 2014 |
Correlation Between Aspirin Intake and Reduced Growth of Human Vestibular Schwannoma: Volumetric Analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Hearing Loss; Humans; Magnetic Resonance I | 2016 |
Duration of Analgesic Use and Risk of Hearing Loss in Women.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dos | 2017 |
Hearing loss in a woman on aspirin: the silent pharmacokinetic parameter.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Progression; Female; Hearing Loss; | 2009 |
Encephalopathy, visual disturbance and hearing loss-recognizing the symptoms of Susac syndrome.
Topics: Aspirin; Auditory Perceptual Disorders; Brain; Cerebral Angiography; Diagnosis, Differential; Diseas | 2009 |
Detection of presumed hemorrhage in the ampullar endolymph of the semicircular canal: a case report.
Topics: Aspirin; Chronic Disease; Contrast Media; Endolymph; Female; Functional Laterality; Gadolinium DTPA; | 2009 |
By the way, doctor. I am 85 and have taken an 81-mg aspirin each day for decades for heart attack prevention. Recently, I noticed these words on the label: "Stop using if you get ringing in your ears or loss of hearing." Should I be worried?
Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Dru | 2010 |
Can aspirin protect or at least attenuate gentamicin ototoxicity in humans?
Topics: Anti-Bacterial Agents; Aspirin; Female; Gentamicins; Hearing Loss; Humans; Male | 2010 |
Effects of aspirin on distortion product fine structure: interpreted by the two-source model for distortion product otoacoustic emissions generation.
Topics: Acoustic Stimulation; Adult; Aspirin; Audiometry; Auditory Threshold; Cochlea; Fourier Analysis; Hea | 2011 |
An unusual case of hearing loss in a patient with neurofibromatosis type 1.
Topics: Age of Onset; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Audiometry, Pure-Tone; Cerebral Angi | 2012 |
Analgesic use and the risk of hearing loss in women.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dr | 2012 |
[Hearing loss].
Topics: Aminoglycosides; Anti-Bacterial Agents; Antineoplastic Agents; Aspirin; Cisplatin; Hearing Loss; Hum | 2012 |
[Reversible hearing loss in acute salicylate intoxication].
Topics: Adaptation, Physiological; Adult; Aspirin; Drug Overdose; Hearing Loss; Humans; Male; Otoacoustic Em | 2004 |
Effect of aspirin on phase gradient of 2F1-F2 distortion product otoacoustic emissions.
Topics: Acoustic Stimulation; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cochlea; Dose-Respons | 2005 |
Neurological picture. Susac's syndrome: effective combination of immunosuppression and antiplatelet treatment.
Topics: Adolescent; Aspirin; Brain Diseases; Corpus Callosum; Female; Glucocorticoids; Hearing Loss; Humans; | 2006 |
Aspirin-induced hearing loss as a model of sensorineural hearing loss.
Topics: Adult; Aspirin; Hearing Loss; Hearing Loss, Sensorineural; Humans; Male; Models, Biological | 1984 |
Aspirin can potentiate the temporary hearing loss induced by intense sounds.
Topics: Adult; Aspirin; Auditory Fatigue; Dose-Response Relationship, Drug; Hearing Loss; Humans; Male; Nois | 1983 |
Frequency selectivity on aspirin-induced hearing loss in rats with auditory stimulus-induced conditioned suppression.
Topics: Acoustic Stimulation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Auditory Threshold; | 1997 |
[Acute aspirin poisoning and deafness. Apropos of 10 cases].
Topics: Acute Disease; Adolescent; Adult; Aspirin; Female; Hearing Loss; Hearing Loss, Bilateral; Humans; Ma | 1979 |
Combined effects of aspirin and noise in causing permanent hearing loss.
Topics: Animals; Aspirin; Drug Synergism; Evoked Potentials, Auditory; Female; Hair Cells, Auditory; Hearing | 1989 |