aspirin has been researched along with Cystic Fibrosis in 18 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An episode of severe small intestinal hemorrhage occurred in a cystic fibrosis patient having pancreatic insufficiency and receiving timed-release aspirin therapy for disabling hypertrophic pulmonary osteoarthropathy." | 3.66 | Possible hazard of timed-release aspirin in a patient with pancreatic insufficiency. ( Davis, PB; di Sant'Agnese, PA; Hubbard, VS, 1979) |
| "Rhinosinusitis is among the most common infectious complications of humoral immunodeficiency, which is not uncommon in patients with refractory CRS." | 2.46 | Rhinosinusitis and comorbidities. ( Brooks, EG; Ryan, MW, 2010) |
| "Rhinosinusitis is among the most common infectious complications of humoral immunodeficiency, and humoral immunodeficiency is not uncommon in patients with refractory chronic rhinosinusitis." | 2.44 | Diseases associated with chronic rhinosinusitis: what is the significance? ( Ryan, MW, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (66.67) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ryan, MW | 2 |
| Brooks, EG | 1 |
| Wu, YZ | 1 |
| Abolhassani, M | 1 |
| Ollero, M | 1 |
| Dif, F | 1 |
| Uozumi, N | 1 |
| Lagranderie, M | 1 |
| Shimizu, T | 1 |
| Chignard, M | 1 |
| Touqui, L | 1 |
| BARNESS, LA | 2 |
| YOUNG, LN | 2 |
| Wladislavosky-Waserman, P | 1 |
| Kern, EB | 1 |
| Holley, KE | 1 |
| Eisenbrey, AB | 1 |
| Gleich, GJ | 1 |
| Noritake, DT | 1 |
| Hen, J | 1 |
| Leo, L | 1 |
| Dolan, TF | 1 |
| Davì, G | 1 |
| Iapichino, L | 1 |
| Balsamo, V | 1 |
| Ganci, A | 1 |
| Giammarresi, C | 1 |
| Patrignani, P | 1 |
| Patrono, C | 1 |
| Groutas, WC | 1 |
| Huang, H | 1 |
| Venkataraman, R | 1 |
| Houser-Archield, N | 1 |
| Epp, JB | 1 |
| Hubbard, VS | 1 |
| Davis, PB | 1 |
| di Sant'Agnese, PA | 1 |
| Wayoff, M | 1 |
| Simon, C | 1 |
| Gazel, P | 1 |
| Athreya, BH | 1 |
| Borns, P | 1 |
| Rosenlund, ML | 1 |
| Sola, JE | 1 |
| Stone, MM | 1 |
| Wise, B | 1 |
| Colombani, PM | 1 |
| Holman, RT | 1 |
| Phillips, BM | 1 |
| David, TJ | 1 |
| Caplin, I | 2 |
| Haynes, JT | 2 |
| Spahn, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of High Omega-3 Fish Intake on Lipid Peroxidation[NCT01183520] | 30 participants (Actual) | Interventional | 2010-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for aspirin and Cystic Fibrosis
| Article | Year |
|---|---|
Rhinosinusitis and comorbidities.
Topics: Anti-Bacterial Agents; Aspirin; Cystic Fibrosis; Humans; Hypersensitivity; Immunity, Humoral; Immuno | 2010 |
Diseases associated with chronic rhinosinusitis: what is the significance?
Topics: Aspirin; Chronic Disease; Cystic Fibrosis; Humans; Hypersensitivity; Immunocompromised Host; Inciden | 2008 |
Control of polyunsaturated acids in tissue lipids.
Topics: Acrodermatitis; alpha-Linolenic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Child; Crohn Dis | 1986 |
Pathogenesis and management of arthropathy in cystic fibrosis.
Topics: Adolescent; Adult; Aspirin; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Joint Diseases | 1986 |
14 other studies available for aspirin and Cystic Fibrosis
| Article | Year |
|---|---|
Cytosolic phospholipase A2alpha mediates Pseudomonas aeruginosa LPS-induced airway constriction of CFTR -/- mice.
Topics: Administration, Intranasal; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Bronchoalveolar L | 2010 |
A SIMPLIFIED VIEW OF FLUID THERAPY.
Topics: Acidosis; Adrenal Insufficiency; Aspirin; Calcium; Child; Cystic Fibrosis; Dehydration; Diabetes Mel | 1964 |
A SIMPLIFIED VIEW OF FLUID THERAPY.
Topics: Acidosis; Adrenal Insufficiency; Anuria; Aspirin; Body Weight; Burns; Calcium; Child; Cystic Fibrosi | 1964 |
Epithelial damage in nasal polyps.
Topics: Adult; Aspirin; Asthma; Cystic Fibrosis; Drug Hypersensitivity; Epithelium; Female; Humans; Male; Mi | 1984 |
The influence of aspirin on lung function in cystic fibrosis.
Topics: Adolescent; Adult; Aspirin; Child; Cystic Fibrosis; Drug Tolerance; Female; Humans; Lung; Male; Resp | 1982 |
Thromboxane biosynthesis and pulmonary function in cystic fibrosis.
Topics: Adolescent; Adult; Aspirin; Blood Platelets; Case-Control Studies; Child; Cystic Fibrosis; Female; G | 1995 |
Dual-action inhibitors of proteolytic enzymes: potential therapeutic agents for cystic fibrosis and related ailments.
Topics: Amino Acid Sequence; Aspirin; Cystic Fibrosis; Drug Design; Humans; In Vitro Techniques; Ketoprofen; | 1993 |
Possible hazard of timed-release aspirin in a patient with pancreatic insufficiency.
Topics: Adult; Aspirin; Cystic Fibrosis; Delayed-Action Preparations; Gastrointestinal Hemorrhage; Humans; I | 1979 |
[Deforming, recurrent nasal polyposis in the adult].
Topics: Adrenal Cortex Hormones; Adult; Aspirin; Asthma; Child; Cystic Fibrosis; Drug Hypersensitivity; Huma | 1979 |
Cystic fibrosis and hypertrophic osteoarthropathy in children. Report of three cases.
Topics: Adolescent; Aspirin; Child; Chronic Disease; Cystic Fibrosis; Female; Humans; Joint Diseases; Male; | 1975 |
Atypical thrombotic and septic complications of totally implantable venous access devices in patients with cystic fibrosis.
Topics: Adolescent; Adult; Aspirin; Catheterization, Central Venous; Catheters, Indwelling; Child; Child, Pr | 1992 |
Nasal polyps.
Topics: Aspirin; Asthma; Child, Preschool; Cystic Fibrosis; Drug Hypersensitivity; Female; Humans; Male; Nas | 1973 |
Possible genetic links between cystic fibrosis of the pancreas and aspirin sensitive asthma.
Topics: Amino Acids; Animals; Aspirin; Asthma; Binding Sites; Cystic Fibrosis; Drug Hypersensitivity; Hetero | 1973 |
Are nasal polyps an allergic phenomenon?
Topics: Aspirin; Asthma; Cystic Fibrosis; Dermatitis, Atopic; Drug Hypersensitivity; Female; Humans; Hyperse | 1971 |