aspirin has been researched along with Complication, Intraoperative in 64 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "ᅟ: We investigated the occurrence of bleeding complications in patients who underwent skin tumor surgery and compared it between Aspirin users and a placebo control group." | 9.22 | Aspirin use and bleeding volume in skin cancer patients undergoing surgery: a randomized controlled trial. ( Atri, A; Engheta, A; Hadadi Abianeh, S; Sanatkarfar, M, 2016) |
| "The aim of this study was to evaluate whether an intraoperative bronchospasm is more frequent in sinus surgery than in non-sinus surgery, whether its appearance after application of a non-steroidal anti-inflammatory drug (NSAID) is an indicator of an aspirin intolerance syndrome, and whether its appearance can be interpreted as an aspirin provocation test." | 7.73 | [Intraoperative bronchospasm during paranasal sinus surgery -- indicator of aspirin intolerance syndrome?]. ( Blidaru, N; Keck, T; Polzehl, D; Rockemann, M; Rozsasi, A; Santak, B, 2006) |
| "Aspirin and nonsteroidal antiinflammatory drugs (NSAIDs) inhibit platelet cyclooxygenase activity, resulting in altered platelet function and thus potentially enhanced bleeding." | 7.69 | Effect of aspirin and nonsteroidal antiinflammatory drug therapy on bleeding complications in dermatologic surgical patients. ( Lawrence, C; Sakuntabhai, A; Tiling-Grosse, S, 1994) |
| "Aspirin was not significantly associated with bleeding complications during or after surgery (p = 0." | 5.42 | A case-control study to assess aspirin as a risk factor of bleeding in rhegmatogenous retinal detachment surgery. ( Albaladejo, P; Aptel, F; Bernheim, D; Brillat, E; Chiquet, C; Palombi, K; Quesada, JL; Romanet, JP; Rouberol, F, 2015) |
| "Tranexamic acid reduces the risk of bleeding among patients undergoing cardiac surgery, but it is unclear whether this leads to improved outcomes." | 5.24 | Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery. ( Bussières, JS; Byrne, K; Chan, MT; Cooper, DJ; Forbes, A; Jayarajah, M; Landoni, G; Marasco, S; McGuinness, S; McNeil, J; Myles, PS; Painter, T; Silbert, B; Smith, JA; Wallace, S, 2017) |
| "ᅟ: We investigated the occurrence of bleeding complications in patients who underwent skin tumor surgery and compared it between Aspirin users and a placebo control group." | 5.22 | Aspirin use and bleeding volume in skin cancer patients undergoing surgery: a randomized controlled trial. ( Atri, A; Engheta, A; Hadadi Abianeh, S; Sanatkarfar, M, 2016) |
| " New data obtained from the Aspirin and Carotid Endarterectomy (ACE) Trial suggest that low-dose aspirin is superior to high-dose aspirin therapy in reducing rates of perioperative stroke and death." | 4.80 | Antiplatelet agents, carotid endarterectomy, and perioperative complications. ( Johnston, KC; Worrall, BB, 2000) |
| "We therefore examined the rate of all perioperative hemorrhages and separately the rate of only severe bleedings during vitrectomy, scleral buckling with or without drainage of subretinal fluid (SRD), or combined procedures due to retinal detachment in patients undergoing different types of perioperative anticoagulation including acetylsalicylic acetate (ASA), clopidogrel, heparin, low molecular weight heparin, and phenprocoumon." | 3.96 | Risk of perioperative bleeding complications in rhegmatogenous retinal detachment surgery: a retrospective single-center study. ( Affeldt, J; Bemme, S; Bertelmann, T; Callizo, J; Feltgen, N; Hoerauf, H; Khattab, MH; Lauermann, P; Pfeiffer, S; Striebe, NA, 2020) |
| "The aim of this study was to evaluate whether an intraoperative bronchospasm is more frequent in sinus surgery than in non-sinus surgery, whether its appearance after application of a non-steroidal anti-inflammatory drug (NSAID) is an indicator of an aspirin intolerance syndrome, and whether its appearance can be interpreted as an aspirin provocation test." | 3.73 | [Intraoperative bronchospasm during paranasal sinus surgery -- indicator of aspirin intolerance syndrome?]. ( Blidaru, N; Keck, T; Polzehl, D; Rockemann, M; Rozsasi, A; Santak, B, 2006) |
| "Aspirin and nonsteroidal antiinflammatory drugs (NSAIDs) inhibit platelet cyclooxygenase activity, resulting in altered platelet function and thus potentially enhanced bleeding." | 3.69 | Effect of aspirin and nonsteroidal antiinflammatory drug therapy on bleeding complications in dermatologic surgical patients. ( Lawrence, C; Sakuntabhai, A; Tiling-Grosse, S, 1994) |
| "Essential thrombocythemia is a chronic myeloproliferative neoplasm characterized by sustained thrombocytosis, bone marrow megakaryocytic hyperplasia and an increased risk of thrombosis and hemorrhage." | 2.49 | [Treatment of essential thrombocythemia]. ( Alvarez-Larrán, A; Besses, C; Cervantes, F, 2013) |
| "Aspirin was not significantly associated with bleeding complications during or after surgery (p = 0." | 1.42 | A case-control study to assess aspirin as a risk factor of bleeding in rhegmatogenous retinal detachment surgery. ( Albaladejo, P; Aptel, F; Bernheim, D; Brillat, E; Chiquet, C; Palombi, K; Quesada, JL; Romanet, JP; Rouberol, F, 2015) |
| "Two hundred and sixty-one cerebral aneurysms were treated in 247 patients by endovascular coil embolization from January 2001 to September 2004." | 1.33 | Intravenous administration of acetylsalicylic acid during endovascular treatment of cerebral aneurysms reduces the rate of thromboembolic events. ( Buhk, JH; Fiehler, J; Goebell, E; Grzyska, U; Kucinski, T; Ries, T; Zeumer, H, 2006) |
| "The aspirin-treated group received an average of 0." | 1.32 | Aspirin therapy and bleeding during proximal femoral fracture surgery. ( Anekstein, Y; Halperin, N; Mirovsky, Y; Tamir, E, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (7.81) | 18.7374 |
| 1990's | 8 (12.50) | 18.2507 |
| 2000's | 31 (48.44) | 29.6817 |
| 2010's | 18 (28.13) | 24.3611 |
| 2020's | 2 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Bemme, S | 1 |
| Lauermann, P | 1 |
| Striebe, NA | 1 |
| Khattab, MH | 1 |
| Affeldt, J | 1 |
| Callizo, J | 1 |
| Bertelmann, T | 1 |
| Pfeiffer, S | 1 |
| Hoerauf, H | 1 |
| Feltgen, N | 1 |
| Vavuranakis, MA | 1 |
| Kalantzis, C | 1 |
| Voudris, V | 1 |
| Kosmas, E | 1 |
| Kalogeras, K | 1 |
| Katsianos, E | 1 |
| Oikonomou, E | 1 |
| Siasos, G | 1 |
| Aznaouridis, K | 1 |
| Toutouzas, K | 1 |
| Stasinopoulou, M | 1 |
| Tountopoulou, A | 1 |
| Bei, E | 1 |
| Moldovan, CM | 1 |
| Vrachatis, D | 1 |
| Iakovou, I | 1 |
| Papaioannou, TG | 1 |
| Tousoulis, D | 1 |
| Leucker, TM | 1 |
| Vavuranakis, M | 1 |
| Oimatsu, Y | 1 |
| Kaikita, K | 1 |
| Ishii, M | 1 |
| Mitsuse, T | 1 |
| Ito, M | 1 |
| Arima, Y | 1 |
| Sueta, D | 1 |
| Takahashi, A | 1 |
| Iwashita, S | 1 |
| Yamamoto, E | 1 |
| Kojima, S | 1 |
| Hokimoto, S | 1 |
| Tsujita, K | 1 |
| Prader, R | 1 |
| De Broca, B | 1 |
| Chevallier, D | 1 |
| Amiel, J | 1 |
| Durand, M | 1 |
| Alvarez-Larrán, A | 1 |
| Cervantes, F | 1 |
| Besses, C | 1 |
| Fujikawa, T | 1 |
| Noda, T | 1 |
| Tada, S | 1 |
| Tanaka, A | 1 |
| Callender, RA | 1 |
| Mukalel, J | 1 |
| Altamirano, AV | 1 |
| Pivalizza, EG | 1 |
| Cattano, D | 1 |
| Sfakianos, JP | 1 |
| Hakimi, AA | 1 |
| Kim, PH | 1 |
| Zabor, EC | 1 |
| Mano, R | 1 |
| Bernstein, M | 1 |
| Karellas, M | 1 |
| Russo, P | 1 |
| Devereaux, PJ | 2 |
| Heinzl, S | 1 |
| Brillat, E | 1 |
| Rouberol, F | 2 |
| Palombi, K | 2 |
| Quesada, JL | 1 |
| Bernheim, D | 1 |
| Albaladejo, P | 2 |
| Aptel, F | 2 |
| Romanet, JP | 2 |
| Chiquet, C | 2 |
| Gallice, M | 1 |
| Brillat Zaratzian, E | 1 |
| Kiberd, MB | 1 |
| Hall, RI | 1 |
| Engheta, A | 1 |
| Hadadi Abianeh, S | 1 |
| Atri, A | 1 |
| Sanatkarfar, M | 1 |
| Kamenova, M | 1 |
| Croci, D | 1 |
| Guzman, R | 1 |
| Mariani, L | 1 |
| Soleman, J | 1 |
| Myles, PS | 1 |
| Smith, JA | 1 |
| Forbes, A | 1 |
| Silbert, B | 1 |
| Jayarajah, M | 1 |
| Painter, T | 1 |
| Cooper, DJ | 1 |
| Marasco, S | 1 |
| McNeil, J | 1 |
| Bussières, JS | 1 |
| McGuinness, S | 1 |
| Byrne, K | 1 |
| Chan, MT | 1 |
| Landoni, G | 1 |
| Wallace, S | 1 |
| Graw, J | 1 |
| Schwenk, W | 1 |
| Volk, T | 1 |
| Estilita, J | 1 |
| Alonso, FM | 1 |
| Brasil, JS | 1 |
| Baptista, MS | 1 |
| van den Bergh, WM | 1 |
| Kerr, RS | 1 |
| Algra, A | 1 |
| Rinkel, GJ | 1 |
| Molyneux, AJ | 1 |
| Jähne, J | 2 |
| Schirren, J | 2 |
| Rottbauer, W | 1 |
| Katus, HA | 1 |
| Bölükbas, S | 1 |
| Martens, A | 1 |
| Haverich, A | 1 |
| Yamasaki, H | 1 |
| Matsubara, S | 1 |
| Sasaki, I | 1 |
| Nagahiro, S | 1 |
| Morofuji, Y | 1 |
| So, G | 1 |
| Hiu, T | 1 |
| Kawakubo, J | 1 |
| Hayashi, K | 1 |
| Kitagawa, N | 1 |
| Morikawa, M | 1 |
| Suyama, K | 1 |
| Nagata, I | 1 |
| Barequet, IS | 1 |
| Sachs, D | 1 |
| Shenkman, B | 1 |
| Priel, A | 1 |
| Wasserzug, Y | 1 |
| Budnik, I | 1 |
| Moisseiev, J | 1 |
| Salomon, O | 1 |
| Brown, JS | 1 |
| Mahmoud, TH | 1 |
| Malik, AI | 1 |
| Foster, RE | 1 |
| Correa, ZM | 1 |
| Petersen, MR | 1 |
| Miller, DM | 1 |
| Riemann, CD | 1 |
| Ouali, S | 1 |
| Anselme, F | 1 |
| Savouré, A | 1 |
| Cribier, A | 1 |
| Narendran, N | 1 |
| Williamson, TH | 1 |
| Otley, CC | 1 |
| Anekstein, Y | 1 |
| Tamir, E | 1 |
| Halperin, N | 1 |
| Mirovsky, Y | 1 |
| Alcalay, J | 1 |
| Alkalay, R | 1 |
| Moore, M | 1 |
| Power, M | 1 |
| Kovacs, MJ | 1 |
| Kearon, C | 1 |
| Rodger, M | 1 |
| Anderson, DR | 1 |
| Turpie, AG | 1 |
| Bates, SM | 1 |
| Desjardins, L | 1 |
| Douketis, J | 1 |
| Kahn, SR | 1 |
| Solymoss, S | 1 |
| Wells, PS | 1 |
| Rozsasi, A | 1 |
| Blidaru, N | 1 |
| Rockemann, M | 1 |
| Santak, B | 1 |
| Polzehl, D | 1 |
| Keck, T | 1 |
| Feringa, HH | 1 |
| Bax, JJ | 1 |
| Schouten, O | 1 |
| Poldermans, D | 1 |
| Ries, T | 1 |
| Buhk, JH | 1 |
| Kucinski, T | 1 |
| Goebell, E | 1 |
| Grzyska, U | 1 |
| Zeumer, H | 1 |
| Fiehler, J | 1 |
| Worrall, BB | 1 |
| Johnston, KC | 1 |
| Korinth, MC | 1 |
| Sun, JZ | 1 |
| Maguire, D | 1 |
| Benzimra, JD | 1 |
| Johnston, RL | 1 |
| Jaycock, P | 1 |
| Galloway, PH | 1 |
| Lambert, G | 1 |
| Chung, AK | 1 |
| Eke, T | 1 |
| Sparrow, JM | 1 |
| Price, J | 1 |
| Tadbiri, S | 1 |
| Fernández-Meré, LA | 1 |
| Fernández Rogríguez, S | 1 |
| Alvarez-Blanco, M | 1 |
| Kennedy, BM | 1 |
| Chen, CT | 1 |
| Toung, TJ | 1 |
| Haupt, HM | 1 |
| Hutchins, GM | 1 |
| Cameron, JL | 1 |
| McKenzie, JE | 1 |
| Cost, EA | 1 |
| Scandling, DM | 1 |
| Ahle, NW | 1 |
| Savage, RW | 1 |
| Lawrence, C | 1 |
| Sakuntabhai, A | 1 |
| Tiling-Grosse, S | 1 |
| Elaxel, CJ | 1 |
| Blach, RK | 1 |
| Ballotta, E | 1 |
| Abbruzzese, E | 1 |
| Thiene, G | 1 |
| Bottio, T | 1 |
| Dagiau, G | 1 |
| Angelini, A | 1 |
| Saladini, M | 1 |
| Rao, SK | 1 |
| Palazzo, RS | 1 |
| Metz, HN | 1 |
| Wilson, DW | 1 |
| Nikolic, SD | 1 |
| Graver, M | 1 |
| Rao, PS | 1 |
| Alvarez, JM | 1 |
| Harper, RW | 1 |
| Peverill, RE | 1 |
| Ardekian, L | 1 |
| Gaspar, R | 1 |
| Peled, M | 1 |
| Brener, B | 1 |
| Laufer, D | 1 |
| Ghali, WA | 1 |
| Gibson, NE | 1 |
| Skjodt, NM | 1 |
| Ford, DC | 1 |
| Quan, H | 1 |
| Guyatt, GH | 1 |
| Pastor, JC | 1 |
| Baílez, C | 1 |
| Aragón, J | 1 |
| Rodríguez de la Rúa, E | 1 |
| Grubitzsch, H | 1 |
| Wollert, HG | 1 |
| Eckel, L | 1 |
| Neilipovitz, DT | 1 |
| Bryson, GL | 1 |
| Nichol, G | 1 |
| D'Ancona, G | 1 |
| Donias, HW | 1 |
| Karamanoukian, RL | 1 |
| Bergsland, J | 1 |
| Karamanoukian, HL | 1 |
| van der Meer, J | 1 |
| Ehlers, R | 1 |
| Felbinger, TW | 1 |
| Eltzschig, HK | 1 |
| Woolson, ST | 1 |
| Watt, JM | 1 |
| Mazzaferro, V | 1 |
| Esquivel, CO | 1 |
| Makowka, L | 1 |
| Belle, S | 1 |
| Kahn, D | 1 |
| Koneru, B | 1 |
| Scantlebury, VP | 1 |
| Stieber, AC | 1 |
| Todo, S | 1 |
| Tzakis, AG | 1 |
| Hindman, BJ | 1 |
| Koka, BV | 1 |
| Barber, A | 1 |
| Green, D | 1 |
| Galluzzo, T | 1 |
| Ts'ao, CH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Large, International, Placebo-controlled, Factorial Trial to Assess the Impact of Clonidine and Acetyl-salicylic Acid (ASA) in Patients Undergoing Noncardiac Surgery Who Are at Risk of a Perioperative Cardiovascular Event[NCT01082874] | Phase 3 | 10,010 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
| The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery[NCT04951128] | Phase 4 | 50 participants (Anticipated) | Interventional | 2021-08-01 | Not yet recruiting | ||
| Tranexamic Acid for the Prevention of Obstetrical Hemorrhage After Cesarean Delivery: A Randomized Controlled Trial[NCT03364491] | Phase 3 | 11,000 participants (Actual) | Interventional | 2018-03-15 | Completed | ||
| Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma. A Double-blind, Placebo-controlled, Multicentre, Randomized Controlled Clinical Trial[NCT03582293] | Phase 3 | 140 participants (Anticipated) | Interventional | 2018-06-19 | Recruiting | ||
| DEPOSITION: Pilot Study Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery[NCT03376061] | Phase 4 | 97 participants (Actual) | Interventional | 2017-12-21 | Completed | ||
| Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery (DEPOSITION) Study[NCT03954314] | Phase 3 | 3,242 participants (Actual) | Interventional | 2019-09-17 | Terminated (stopped due to Upon the Data Safety Monitoring Board review of the interim analysis (75% of participants have finished their follow-up) on November 17, 2023, they made a recommendation to stop recruitment into the trial.) | ||
| A Double Blind Randomized Control Trial of Post-Operative Low Molecular Weight Heparin Bridging Therapy Versus Placebo Bridging Therapy for Patients Who Are at High Risk for Arterial Thromboembolism (PERIOP 2)[NCT00432796] | Phase 3 | 1,473 participants (Actual) | Interventional | 2006-12-31 | Active, not recruiting | ||
| China Research for Severe Spontaneous Intracerebral Hemorrhage（CRISIH）[NCT05975398] | 450 participants (Anticipated) | Observational [Patient Registry] | 2022-07-01 | Recruiting | |||
| Effect and Safety of Surgical Intervention for Severe Spontaneous Intracerebral Hemorrhage Patients on Long-term Oral Antiplatelet Treatment[NCT05766865] | 450 participants (Actual) | Observational | 2019-07-10 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01082874)
Timeframe: 30 days
| Intervention | participants (Number) |
|---|---|
| Active Clonidine and Active ASA | 173 |
| Active Clonidine and Placebo ASA | 194 |
| Placebo Clonidine and Active ASA | 178 |
| Placebo Clonidine and Placebo ASA | 161 |
[Key secondary outcome] Change in hemoglobin from the most recent measured before delivery to lowest measured in the 48 hours after delivery (NCT03364491)
Timeframe: from 4 weeks before delivery to 48 hours postpartum
| Intervention | grams per deciliter (Mean) |
|---|---|
| Tranexamic Acid | -1.8 |
| Placebo | -1.9 |
Mother's length of stay from delivery to discharge (NCT03364491)
Timeframe: Until hospital discharge, an average of 3 days
| Intervention | days (Median) |
|---|---|
| Tranexamic Acid | 3 |
| Placebo | 3 |
(NCT03364491)
Timeframe: within 6 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 35 |
| Placebo | 32 |
This is the number of mothers who were treated with any amount of open-label TXA (not blinded study drug) or another antifibrinolytic (eg., Amicar) (NCT03364491)
Timeframe: within 7 days postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 108 |
| Placebo | 109 |
This is the number of mothers who required any of the following types of surgical procedures to control bleeding: laparotomy, evacuation of hematoma, hysterectomy, uterine packing, intrauterine balloon tamponade, interventional radiology (NCT03364491)
Timeframe: within 7 days postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 233 |
| Placebo | 231 |
[Key secondary outcome] This is the number of mothers who received treatments and interventions to control bleeding such as: uterotonics such as prostaglandins or methergine, but excluding oxytocin; open label TXA or other antifibrinolytics; transfusion of 1 or more units of fresh frozen plasma, cryoprecipitate, or platelets or administration of any factor concentrates; laparotomy, evacuation of hematoma, hysterectomy, uterine packing, intrauterine balloon tamponade, interventional radiology (NCT03364491)
Timeframe: within 7 days postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 892 |
| Placebo | 986 |
Participants were categorized according to the amount of packed red blood cells or whole blood transfused, either as 0 to 3 units, or 4 or more units (NCT03364491)
Timeframe: within 7 days postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 20 |
| Placebo | 19 |
This is the number of mothers who received during the first 7 days after delivery a transfusion of 1 or more units of fresh frozen plasma, cryoprecipitate, or platelets, or received any factor concentrates (NCT03364491)
Timeframe: within 7 days postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 29 |
| Placebo | 31 |
This is the number of mothers who were treated with uterotonics such as prostaglandins or methergine, but excluding oxytocin, from delivery through 48 hours after delivery. (NCT03364491)
Timeframe: within 48 hours postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 649 |
| Placebo | 732 |
[Key secondary outcome] This is the number of mothers who experienced a thromboembolic event, ischemic stroke, or myocardial infarction during the 6 weeks after delivery. (NCT03364491)
Timeframe: within 6 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 12 |
| Placebo | 13 |
[Major secondary outcome] The surgeon or anesthesiologist estimated the blood loss during the delivery in milliliters, which was recorded in the anesthesia record and/or operative report (NCT03364491)
Timeframe: From skin incision to transfer from operating room, average of 1 hour
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 339 |
| Placebo | 368 |
Participants were monitored from delivery until hospital discharge or 7 days after delivery (postpartum), whichever is sooner. This is the number of mothers who died for any reason, or had a blood transfusion of 1 or more units (of packed red blood cells, including whole blood or cell saver). (NCT03364491)
Timeframe: by hospital discharge or by 7 days postpartum, whichever is sooner
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 201 |
| Placebo | 233 |
[Key Secondary Outcome] This is the number of mothers who experienced any of the following infectious complications in the 6 weeks after delivery: endometritis, surgical site infection, pelvic abscess (NCT03364491)
Timeframe: within 6 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 162 |
| Placebo | 125 |
This is the number of mothers who experienced seizure activity, confirmed by central review, whose onset is after enrollment (NCT03364491)
Timeframe: within 6 weeks postpartum
| Intervention | Participants (Count of Participants) |
|---|---|
| Tranexamic Acid | 2 |
| Placebo | 0 |
Plasma TxA concentrations measured from blood samples taken upon arrival in the ICU (NCT03376061)
Timeframe: on arrival in ICU within 3 hours
| Intervention | microgram per milliliter per kilogram (Mean) |
|---|---|
| Topical TxA (Intervention) | 0.58 |
| Intravenous TxA (Control) | 1.10 |
Number of hours participants spent in the intensive care unit (ICU) (NCT03376061)
Timeframe: Number of hours spent in ICU from arrival to exit (collected at the Post-Operative Visit).
| Intervention | hours (Median) |
|---|---|
| Topical TxA (Intervention) | 23 |
| Intravenous TxA (Control) | 26 |
Cumulative volume (mL) of fluid collected from mediastinal drainage tubes 24 hours after the surgical procedure (NCT03376061)
Timeframe: Fluid collected in the first 24 hours after the surgical procedure
| Intervention | mL (Median) |
|---|---|
| Topical TxA (Intervention) | 500 |
| Intravenous TxA (Control) | 540 |
The occurrence of death due to any cause (NCT03376061)
Timeframe: Patients will be followed post-operatively until hospital discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| Topical TxA (Intervention) | 1 |
| Intravenous TxA (Control) | 1 |
Patients requiring a red blood cell transfusion (NCT03376061)
Timeframe: Intra-operative and post-operative RBC transfusions
| Intervention | Participants (Count of Participants) |
|---|---|
| Topical TxA (Intervention) | 19 |
| Intravenous TxA (Control) | 23 |
Occurrence of re-operation for the purpose of bleeding or cardiac tamponade (NCT03376061)
Timeframe: Patients will be followed post-operatively until hospital discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| Topical TxA (Intervention) | 0 |
| Intravenous TxA (Control) | 1 |
Patients experiencing a post-operative seizure (NCT03376061)
Timeframe: Patients will be followed post-operatively until hospital discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| Topical TxA (Intervention) | 0 |
| Intravenous TxA (Control) | 1 |
12 reviews available for aspirin and Complication, Intraoperative
| Article | Year |
|---|---|
[Treatment of essential thrombocythemia].
Topics: Adult; Age Factors; Aged; Anticoagulants; Aspirin; Cell Transformation, Neoplastic; Disease Progress | 2013 |
[Managing antithrombotic therapy in vitreoretinal surgery].
Topics: Anesthesia, Local; Anticoagulants; Aspirin; Blood Coagulation; Eye Diseases; Fibrinolytic Agents; He | 2015 |
Aspirin in the perioperative period: a review of the recent literature.
Topics: Aspirin; Drug Interactions; Humans; Intraoperative Complications; Perioperative Care; Perioperative | 2015 |
[Drug-eluting stents: implications for modern coronary revascularization].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Bias; Clopidogrel; Comorbidity; Coronary Artery Bypass; Cor | 2009 |
Continuation of medically necessary aspirin and warfarin during cutaneous surgery.
Topics: Anticoagulants; Aspirin; Dermatologic Surgical Procedures; Hemorrhage; Humans; Intraoperative Compli | 2003 |
Controversies in perioperative management of blood thinners in dermatologic surgery: continue or discontinue?
Topics: Anticoagulants; Aspirin; Blood Loss, Surgical; Humans; Intraoperative Care; Intraoperative Complicat | 2004 |
Antiplatelet agents, carotid endarterectomy, and perioperative complications.
Topics: Aspirin; Endarterectomy, Carotid; Humans; Intraoperative Complications; Models, Biological; Platelet | 2000 |
How to prevent perioperative myocardial injury: the conundrum continues.
Topics: Adrenergic Agents; Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Bypass; Heart Diseases; | 2007 |
Aspirin and surgery--a review.
Topics: Adult; Aspirin; Bleeding Time; Dose-Response Relationship, Drug; Epoprostenol; Ethanol; Female; Hemo | 1984 |
[Treatment of the massive suprachoroidal hemorrhages].
Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blindness; Cataract Extraction; Comor | 2001 |
The effect of perioperative aspirin therapy in peripheral vascular surgery: a decision analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Decision Support Techniques; Hemorrhage; Humans; I | 2001 |
[Aspirin, a risk factor for bleeding at dental procedures].
Topics: Antifibrinolytic Agents; Aspirin; Blood Loss, Surgical; Humans; Intraoperative Complications; Oral H | 1995 |
11 trials available for aspirin and Complication, Intraoperative
| Article | Year |
|---|---|
Comparison of Ticagrelor Versus Clopidogrel on Cerebrovascular Microembolic Events and Platelet Inhibition during Transcatheter Aortic Valve Implantation.
Topics: Aged; Aged, 80 and over; Aortic Valve Stenosis; Aspirin; Clopidogrel; Dual Anti-Platelet Therapy; Fe | 2021 |
Rationale and design of the PeriOperative ISchemic Evaluation-2 (POISE-2) trial: an international 2 × 2 factorial randomized controlled trial of acetyl-salicylic acid vs. placebo and clonidine vs. placebo in patients undergoing noncardiac surgery.
Topics: Aged; Aspirin; Clonidine; Double-Blind Method; Female; Humans; Intraoperative Complications; Male; M | 2014 |
Aspirin use and bleeding volume in skin cancer patients undergoing surgery: a randomized controlled trial.
Topics: Aged; Anticoagulants; Aspirin; Double-Blind Method; Female; Hemorrhage; Humans; Intraoperative Compl | 2016 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery.
Topics: Aged; Aged, 80 and over; Antifibrinolytic Agents; Aspirin; Blood Transfusion; Coronary Artery Bypass | 2017 |
Effect of antiplatelet therapy for endovascular coiling in aneurysmal subarachnoid hemorrhage.
Topics: Aspirin; Data Collection; Female; Humans; Intraoperative Complications; Male; Middle Aged; Neurosurg | 2009 |
Single-arm study of bridging therapy with low-molecular-weight heparin for patients at risk of arterial embolism who require temporary interruption of warfarin.
Topics: Anticoagulants; Arterial Occlusive Diseases; Aspirin; Atrial Fibrillation; Blood Loss, Surgical; Coh | 2004 |
Protecting the heart with cardiac medication in patients with left ventricular dysfunction undergoing major noncardiac vascular surgery.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitor | 2006 |
The elongation of the internal carotid artery: early and long-term results of patients having surgery compared with unoperated controls.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Carotid Artery Diseases; Carotid Artery, Internal; Cerebrov | 1997 |
Does low-dose aspirin therapy complicate oral surgical procedures?
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Loss, Surgical; Female; Humans; | 2000 |
The effect of perioperative aspirin therapy in peripheral vascular surgery: a decision analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Decision Support Techniques; Hemorrhage; Humans; I | 2001 |
Intermittent pneumatic compression to prevent proximal deep venous thrombosis during and after total hip replacement. A prospective, randomized study of compression alone, compression and aspirin, and compression and low-dose warfarin.
Topics: Adult; Age Factors; Aged; Aspirin; Bandages; Combined Modality Therapy; Female; Heparin; Hip Prosthe | 1991 |
42 other studies available for aspirin and Complication, Intraoperative
| Article | Year |
|---|---|
Risk of perioperative bleeding complications in rhegmatogenous retinal detachment surgery: a retrospective single-center study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Child; Child, Preschool; Clopid | 2020 |
Total Thrombus-formation Analysis System Predicts Periprocedural Bleeding Events in Patients With Coronary Artery Disease Undergoing Percutaneous Coronary Intervention.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Coagulation Tests; Clopidogrel; Coronary Artery Disease; Fem | 2017 |
Outcome of Transurethral Resection of Bladder Tumor: Does Antiplatelet Therapy Really Matter? Analysis of a Retrospective Series.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Loss, Surgical; Carcinoma, Transitional Cell; Clopidogrel; C | 2017 |
Intractable intraoperative bleeding requiring platelet transfusion during emergent cholecystectomy in a patient with dual antiplatelet therapy after drug-eluting coronary stent implantation (with video).
Topics: Aged; Aspirin; Blood Loss, Surgical; Cholecystectomy; Coronary Artery Disease; Drug-Eluting Stents; | 2013 |
Hidden implications: potential antiplatelet effects of adjuvant anaesthetic agents.
Topics: Adenosine Diphosphate; Adjuvants, Anesthesia; Aged; Aspirin; Cholecystectomy, Laparoscopic; Clopidog | 2013 |
Outcomes in patients undergoing nephrectomy for renal cancer on chronic anticoagulation therapy.
Topics: Age Factors; Aged; Anticoagulants; Aspirin; Blood Transfusion; Female; Fibrinolytic Agents; Humans; | 2014 |
[Can perioperative aspirin prevent heart attacks?].
Topics: Aspirin; Heart Diseases; Humans; Intraoperative Complications; Perioperative Care; Platelet Aggregat | 2014 |
A case-control study to assess aspirin as a risk factor of bleeding in rhegmatogenous retinal detachment surgery.
Topics: Aged; Aspirin; Case-Control Studies; Choroid Hemorrhage; Cryotherapy; Female; Humans; Intraoperative | 2015 |
Low-dose acetylsalicylic acid and bleeding risks with ventriculoperitoneal shunt placement.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Female; Humans; Intraoperative Complications; Male; Middle | 2016 |
[Perioperative discontinuation of antiplatelet therapy of patients with coronary stents. Reevaluating the risks].
Topics: Algorithms; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Decision Tree | 2009 |
[Intradural block in essential thrombocytosis].
Topics: Aged, 80 and over; Anesthesia, Spinal; Aspirin; Female; Fracture Fixation, Internal; Hematoma, Epidu | 2009 |
[Introduction to the topic: drug eluting stents. An underestimated problem in surgery].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Coronary Restenosis; Drug-Eluting Stents; Hemo | 2009 |
[Patients with coronary artery stents: when and how should operations be carried out?].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cooperative Behavior; Coronary Restenosis; Dru | 2009 |
[Drug-eluting stents: implications for surgery patients].
Topics: Algorithms; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Cooperative Behavior; Coronary Res | 2009 |
Retinal artery embolization during carotid angioplasty and carotid artery stenting: case report.
Topics: Aged; Angioplasty, Balloon; Anticoagulants; Antipyrine; Aspirin; Carotid Artery, External; Carotid S | 2009 |
[Preoperative analysis of platelet aggregability in carotid surgery].
Topics: Aged; Aged, 80 and over; Aspirin; Carotid Arteries; Clopidogrel; Endarterectomy, Carotid; Female; Hu | 2011 |
Risk assessment of simple phacoemulsification in patients on combined anticoagulant and antiplatelet therapy.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aspirin; Blood Loss, Surgical; Clopidogrel; Drug Therapy, C | 2011 |
Anticoagulation and clinically significant postoperative vitreous hemorrhage in diabetic vitrectomy.
Topics: Anticoagulants; Aspirin; Clopidogrel; Diabetic Retinopathy; Female; Humans; Incidence; Intraoperativ | 2011 |
Anatomical and visual results of transconjunctival sutureless vitrectomy using subconjunctival anesthesia performed on select patients taking anticoagulant and antiplatelet agents.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Anticoagulants; Aspirin; Bupi | 2012 |
Acute coronary occlusion during radiofrequency catheter ablation of typical atrial flutter.
Topics: Acute Disease; Aged; Aspirin; Atrial Flutter; Catheter Ablation; Coronary Disease; Electrocardiograp | 2002 |
The effects of aspirin and warfarin therapy on haemorrhage in vitreoretinal surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Child; Choroid Hemorrhage; Cont | 2003 |
Aspirin therapy and bleeding during proximal femoral fracture surgery.
Topics: Aged; Aspirin; Blood Loss, Surgical; Case-Control Studies; Femoral Fractures; Humans; Intraoperative | 2004 |
Perioperative hemorrhage and combined clopidogrel and aspirin therapy.
Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Drug Combinations; Endarterectomy, Carotid; Female; G | 2004 |
[Intraoperative bronchospasm during paranasal sinus surgery -- indicator of aspirin intolerance syndrome?].
Topics: Acetaminophen; Adult; Aged; Algorithms; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal | 2006 |
Intravenous administration of acetylsalicylic acid during endovascular treatment of cerebral aneurysms reduces the rate of thromboembolic events.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Drug Evaluation; Embolization, Therape | 2006 |
Low-dose aspirin before intracranial surgery--results of a survey among neurosurgeons in Germany.
Topics: Aspirin; Cerebral Hemorrhage; Clinical Protocols; Deamino Arginine Vasopressin; Germany; Hemostatics | 2006 |
Low-dose aspirin before intracranial surgery--results of a survey among neurosurgeons in Germany.
Topics: Aspirin; Cerebral Hemorrhage; Clinical Protocols; Deamino Arginine Vasopressin; Germany; Hemostatics | 2006 |
Low-dose aspirin before intracranial surgery--results of a survey among neurosurgeons in Germany.
Topics: Aspirin; Cerebral Hemorrhage; Clinical Protocols; Deamino Arginine Vasopressin; Germany; Hemostatics | 2006 |
Low-dose aspirin before intracranial surgery--results of a survey among neurosurgeons in Germany.
Topics: Aspirin; Cerebral Hemorrhage; Clinical Protocols; Deamino Arginine Vasopressin; Germany; Hemostatics | 2006 |
The Cataract National Dataset electronic multicentre audit of 55,567 operations: antiplatelet and anticoagulant medications.
Topics: Aged; Anesthetics, Local; Anticoagulants; Aspirin; Blood Loss, Surgical; Cataract Extraction; Choroi | 2009 |
Aspirin and clopidogrel use in the perioperative period for non-cardiac surgery.
Topics: Aspirin; Blood Loss, Surgical; Clopidogrel; Drug-Eluting Stents; Humans; Intraoperative Complication | 2008 |
[Stents, antiplatelet therapy, and surgery].
Topics: Adult; Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Cesarean Section; Enoxaparin; Female | 2008 |
Evaluation of the efficacy of Alka-Seltzer Effervescent in gastric acid neutralization.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Animals; Aspirin; Bicarbonates; Child; Citrates; Dogs; | 1984 |
Effects of diaspirin crosslinked haemoglobin during coronary angioplasty in the swine.
Topics: Angioplasty, Balloon, Coronary; Animals; Aspirin; Coronary Circulation; Electrocardiography; Female; | 1994 |
Effect of aspirin and nonsteroidal antiinflammatory drug therapy on bleeding complications in dermatologic surgical patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bandages; Blood Co | 1994 |
Aspirin is a hazard for vitreoretinal surgery.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Contraindications; Emergencies; Humans; Intr | 1996 |
Redox potential measurements of plasma in patients undergoing coronary artery bypass graft and its clinical significance.
Topics: Anticoagulants; Aprotinin; Aspirin; Coronary Artery Bypass; Electrophysiology; Heparin; Heparin Anta | 1997 |
Emergency coronary artery bypass grafting (CABG) after failed coronary artery intervention--caution regarding the combined use of aspirin, ticlopidine and abciximab.
Topics: Abciximab; Adult; Angina Pectoris; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; | 1998 |
Physicians' recommendations for patients who undergo noncardiac surgery.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Calcium Chann | 2000 |
Emergency coronary artery bypass grafting: does excessive preoperative anticoagulation increase bleeding complications and transfusion requirements?
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Aspirin; Blood Transfusion, Autologous; Cardiopulmon | 2001 |
OPCAB therapy survey: off-pump clopidogrel, aspirin or both therapy survey.
Topics: Anticoagulants; Aspirin; Canada; Cardiology; Clopidogrel; Combined Modality Therapy; Coronary Artery | 2001 |
Lowering cardiac risk in noncardiac surgery.
Topics: Aspirin; Cardiovascular Diseases; Humans; Intraoperative Complications; Platelet Aggregation Inhibit | 2002 |
Hepatic artery thrombosis after pediatric liver transplantation--a medical or surgical event?
Topics: Anastomosis, Surgical; Aspirin; Blood Coagulation Tests; Celiac Artery; Child; Child, Preschool; Dex | 1989 |
Usefulness of the post-aspirin bleeding time.
Topics: Adolescent; Aspirin; Bleeding Time; Blood Platelets; Hemorrhage; Hemostasis; Humans; Intraoperative | 1986 |
The bleeding time as a preoperative screening test.
Topics: Aspirin; Bleeding Time; Blood Coagulation Disorders; Hemorrhage; Humans; Intraoperative Complication | 1985 |