aspirin has been researched along with Community Acquired Infection in 6 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study shows that chronic aspirin use is associated with lower mortality rate within 30 days after hospital admission in a large cohort of patients with pneumonia." | 7.81 | Lower mortality rate in elderly patients with community-onset pneumonia on treatment with aspirin. ( Barillà, F; Bertazzoni, G; Calvieri, C; Cangemi, R; Falcone, M; Farcomeni, A; Palange, P; Russo, A; Scarpellini, MG; Taliani, G; Venditti, M; Violi, F, 2015) |
| "MI is an early complication of pneumonia and is associated with in vivo platelet activation and serum TxB2 overproduction; aspirin 100 mg/day seems insufficient to inhibit thromboxane biosynthesis." | 5.19 | Platelet activation is associated with myocardial infarction in patients with pneumonia. ( Bertazzoni, G; Bucci, T; Calabrese, CM; Calvieri, C; Cangemi, R; Casciaro, M; Falcone, M; Farcomeni, A; Grieco, S; Palange, P; Pignatelli, P; Rossi, E; Taliani, G; Violi, F, 2014) |
| "This study shows that chronic aspirin use is associated with lower mortality rate within 30 days after hospital admission in a large cohort of patients with pneumonia." | 3.81 | Lower mortality rate in elderly patients with community-onset pneumonia on treatment with aspirin. ( Barillà, F; Bertazzoni, G; Calvieri, C; Cangemi, R; Falcone, M; Farcomeni, A; Palange, P; Russo, A; Scarpellini, MG; Taliani, G; Venditti, M; Violi, F, 2015) |
| "Aspirin treatment significantly enhanced the killing of KP-M1 by leukocytes (p < 0." | 1.40 | Aspirin enhances opsonophagocytosis and is associated to a lower risk for Klebsiella pneumoniae invasive syndrome. ( Chang, CC; Chen, RF; Lee, CH; Liu, JW; Su, LH; Yang, KD, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Falcone, M | 4 |
| Russo, A | 3 |
| Shindo, Y | 1 |
| Farcomeni, A | 4 |
| Pieralli, F | 2 |
| Cangemi, R | 3 |
| Liu, J | 1 |
| Xia, J | 1 |
| Okumura, J | 1 |
| Sano, M | 1 |
| Jones, C | 1 |
| Vannucchi, V | 2 |
| Mancone, M | 1 |
| Micek, S | 1 |
| Xu, F | 1 |
| Violi, F | 4 |
| Kollef, M | 1 |
| Lee, CH | 1 |
| Su, LH | 1 |
| Liu, JW | 1 |
| Chang, CC | 1 |
| Chen, RF | 1 |
| Yang, KD | 1 |
| Casciaro, M | 1 |
| Rossi, E | 1 |
| Calvieri, C | 2 |
| Bucci, T | 1 |
| Calabrese, CM | 1 |
| Taliani, G | 2 |
| Palange, P | 2 |
| Bertazzoni, G | 2 |
| Grieco, S | 1 |
| Pignatelli, P | 1 |
| Barillà, F | 1 |
| Scarpellini, MG | 1 |
| Venditti, M | 2 |
| Vullo, V | 1 |
| Corrales-Medina, VF | 1 |
| Musher, DM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Corticosteroids On MyocardiaL Injury Among Patients Hospitalized for Community-AcquirEd PneUMonia - COLOSSEUM TRIAL[NCT03745664] | Phase 3 | 122 participants (Anticipated) | Interventional | 2021-01-10 | Recruiting | ||
| Major Adverse Cardiac and Cerebrovascular Events in Hospitalized Patients With Community-acquired Pneumonia[NCT01773863] | 500 participants (Anticipated) | Observational | 2011-10-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for aspirin and Community Acquired Infection
| Article | Year |
|---|---|
Immunomodulatory agents in the treatment of community-acquired pneumonia: a systematic review.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents; Aspirin; Community-Acquire | 2011 |
1 trial available for aspirin and Community Acquired Infection
| Article | Year |
|---|---|
Platelet activation is associated with myocardial infarction in patients with pneumonia.
Topics: Aged; Aspirin; Biomarkers; CD40 Ligand; Community-Acquired Infections; Electrocardiography; Female; | 2014 |
Platelet activation is associated with myocardial infarction in patients with pneumonia.
Topics: Aged; Aspirin; Biomarkers; CD40 Ligand; Community-Acquired Infections; Electrocardiography; Female; | 2014 |
Platelet activation is associated with myocardial infarction in patients with pneumonia.
Topics: Aged; Aspirin; Biomarkers; CD40 Ligand; Community-Acquired Infections; Electrocardiography; Female; | 2014 |
Platelet activation is associated with myocardial infarction in patients with pneumonia.
Topics: Aged; Aspirin; Biomarkers; CD40 Ligand; Community-Acquired Infections; Electrocardiography; Female; | 2014 |
4 other studies available for aspirin and Community Acquired Infection
| Article | Year |
|---|---|
A Hypothesis-Generating Study of the Combination of Aspirin plus Macrolides in Patients with Severe Community-Acquired Pneumonia.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ch | 2019 |
Aspirin enhances opsonophagocytosis and is associated to a lower risk for Klebsiella pneumoniae invasive syndrome.
Topics: Aged; Aspirin; Bacteremia; Bacterial Capsules; Community-Acquired Infections; Female; Humans; Klebsi | 2014 |
Lower mortality rate in elderly patients with community-onset pneumonia on treatment with aspirin.
Topics: Aged; Aged, 80 and over; Aspirin; Case-Control Studies; Community-Acquired Infections; Confidence In | 2015 |
Septic shock from community-onset pneumonia: is there a role for aspirin plus macrolides combination?
Topics: Anti-Bacterial Agents; Aspirin; Community-Acquired Infections; Drug Combinations; Humans; Macrolides | 2016 |