aspirin has been researched along with Colitis-Associated Cancer in 4 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inflammation is linked with carcinogenesis in many types of cancer including colorectal cancer (CRC)." | 1.72 | Aspirin activates resolution pathways to reprogram T cell and macrophage responses in colitis-associated colorectal cancer. ( Austin-Williams, S; Colas, RA; Dalli, J; De Matteis, R; Flak, MB; Gonzalez-Nunez, M; Palmas, F, 2022) |
| " An initial dosing study performed in healthy mice indicates that aspirin at a dose of 25 mg/kg/d has a similar pharmacodynamic effect as low-dose aspirin treatment in human subjects (100 mg/d)." | 1.56 | Effects of chronic low-dose aspirin treatment on tumor prevention in three mouse models of intestinal tumorigenesis. ( Hartung, NM; Kühl, AA; McDonald, FM; Ostermann, AI; Rohwer, N; Schebb, NH; Weylandt, KH; Zopf, D, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Matteis, R | 1 |
| Flak, MB | 1 |
| Gonzalez-Nunez, M | 1 |
| Austin-Williams, S | 1 |
| Palmas, F | 1 |
| Colas, RA | 1 |
| Dalli, J | 1 |
| Babu, SSN | 1 |
| Singla, S | 1 |
| Jena, G | 1 |
| Rohwer, N | 1 |
| Kühl, AA | 1 |
| Ostermann, AI | 1 |
| Hartung, NM | 1 |
| Schebb, NH | 1 |
| Zopf, D | 1 |
| McDonald, FM | 1 |
| Weylandt, KH | 1 |
| Feng, Y | 1 |
| Tao, L | 1 |
| Wang, G | 1 |
| Li, Z | 1 |
| Yang, M | 1 |
| He, W | 1 |
| Zhong, X | 1 |
| Zhang, Y | 1 |
| Yang, J | 1 |
| Cheung, S | 1 |
| McDonald, F | 1 |
| Chen, L | 1 |
4 other studies available for aspirin and Colitis-Associated Cancer
| Article | Year |
|---|---|
Aspirin activates resolution pathways to reprogram T cell and macrophage responses in colitis-associated colorectal cancer.
Topics: Animals; Aspirin; CD8-Positive T-Lymphocytes; Colitis-Associated Neoplasms; Inflammation; Macrophage | 2022 |
Role of Combination Treatment of Aspirin and Zinc in DMH-DSS-induced Colon Inflammation, Oxidative Stress and Tumour Progression in Male BALB/c Mice.
Topics: Animals; Antioxidants; Aspirin; Colitis; Colitis-Associated Neoplasms; Colon; Disease Models, Animal | 2023 |
Effects of chronic low-dose aspirin treatment on tumor prevention in three mouse models of intestinal tumorigenesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Azoxymethane; Carcinogens; Cel | 2020 |
Aspirin inhibits prostaglandins to prevents colon tumor formation via down-regulating Wnt production.
Topics: Animals; Aspirin; Azoxymethane; Cell Transformation, Neoplastic; Colitis; Colitis-Associated Neoplas | 2021 |