Page last updated: 2024-10-23

aspirin and Colitis, Granulomatous

aspirin has been researched along with Colitis, Granulomatous in 40 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) are anti-inflammatory but have been linked in some studies to Crohn disease (CD) and ulcerative colitis (UC)."7.78Aspirin, nonsteroidal anti-inflammatory drug use, and risk for Crohn disease and ulcerative colitis: a cohort study. ( Ananthakrishnan, AN; Chan, AT; Fuchs, CS; Higuchi, LM; Huang, ES; Khalili, H; Richter, JM, 2012)
"Twenty-four patients with spondylitis and Crohn's disease or ulcerative colitis, treated with 5-ASA or sulfasalazine, were randomised and assessed by an investigator independent from the spa staff: 12 were submitted to a cycle of mud-bath treatment (12 mud packs and 12 thermal baths over a period of two weeks) and 12 were enrolled as controls."5.12Mud-bath treatment in spondylitis associated with inflammatory bowel disease--a pilot randomised clinical trial. ( Cardinale, G; Cozzi, F; Dani, L; Oliviero, F; Podswiadek, M; Punzi, L; Sfriso, P, 2007)
"Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) are anti-inflammatory but have been linked in some studies to Crohn disease (CD) and ulcerative colitis (UC)."3.78Aspirin, nonsteroidal anti-inflammatory drug use, and risk for Crohn disease and ulcerative colitis: a cohort study. ( Ananthakrishnan, AN; Chan, AT; Fuchs, CS; Higuchi, LM; Huang, ES; Khalili, H; Richter, JM, 2012)
"Takayasu's arteritis (TA) and Crohn's disease (CD) are chronic inflammatory diseases of uncertain etiology."2.47Rare case of Takayasu's arteritis associated with Crohn's disease. ( Amano, Y; Fukuba, N; Ishihara, S; Kinoshita, Y; Kusunoki, R; Mishima, Y; Moriyama, I; Murakawa, Y; Oka, A; Okada, M; Oshima, N; Sato, M; Sato, S; Sumita, Y; Tada, Y; Yuki, T, 2011)
"The standard therapy in Crohn's disease and ulcerative colitis is based on corticosteroids and aminosalicylates."2.41[Therapy of chronic inflammatory bowel diseases]. ( Stange, EF, 2002)
"The role of salicylates in Crohn's disease is limited to the mild activity phase; further data are required to clarify its role in maintenance on remission."2.41New steroids and new salicylates in inflammatory bowel disease: a critical appraisal. ( Campieri, M, 2002)
"A 50-year-old woman with a history of Crohn's disease treated with adalimumab presented with left hand pain and duskiness."1.56Digital ischaemia secondary to adalimumab-induced antiphospholipid syndrome. ( Cheemalavagu, S; Knight, JS; McCoy, SS, 2020)
"The aetiology of Crohn's disease is poorly understood."1.48Gut Barrier Dysfunction-A Primary Defect in Twins with Crohn's Disease Predominantly Caused by Genetic Predisposition. ( Halfvarson, J; Keita, ÅV; Lindqvist, CM; Magana, CDL; Öst, Å; Schoultz, I, 2018)
"Aspirin has detrimental effects on the gastrointestinal tract mucosa and may play a role in the aetiology of inflammatory bowel disease."1.37Aspirin in the aetiology of Crohn's disease and ulcerative colitis: a European prospective cohort study. ( Bergmann, MM; Boeing, H; Chan, SS; Hart, AR; Kaaks, R; Kennedy, H; Khaw, KT; Luben, R; Olsen, A; Overvad, K; Riboli, E; Tjonneland, A, 2011)
"First, patients with quiescent Crohn's disease and ulcerative colitis received the non-NSAID analgesic acetaminophen (n = 26) and the conventional NSAIDs naproxen (n = 32), diclofenac (n = 29), and indomethacin (n = 22) for 4 weeks."1.33Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease. ( Bjarnason, I; Bjornsson, E; Maiden, L; Premchand, P; Sherwood, R; Smale, S; Takeuchi, K; Thjodleifsson, B, 2006)
"Fifty-eight ulcerative colitis patients were seen with active disease, with eight (13."1.31Tolerance of nonsteroidal antiinflammatory drugs in patients with inflammatory bowel disease. ( Bayona, M; Bonner, GF; Kitchen, L; Walczak, M, 2000)
"Esophageal involvement by Crohn's disease should be suspected in any patient previously diagnosed with this disease who presents symptoms suggestive of esophagitis, using endoscopy with multiples biopsies of the affected areas and other of normal endoscopic appearance for diagnosis."1.30[Esophageal Crohn's disease]. ( Aparicio Tormo, JR; Casellas Valdé, JA; Martínez Sempere, JF; Moya García, MI; Palazón Azorín, JM; Trigueros Mateos, M, 1997)
"The study included 39 patients with Crohn's disease, 34 healthy first degree relatives, and 22 spouses."1.30Different intestinal permeability patterns in relatives and spouses of patients with Crohn's disease: an inherited defect in mucosal defence? ( Hannestad, U; Järnerot, G; Lindberg, E; Olaison, G; Sjödahl, R; Söderholm, JD; Tysk, C; Vindels, A, 1999)
"First-degree relatives of patients with Crohn's disease have an exaggerated increase in intestinal but not gastroduodenal permeability in response to acetylsalicylic acid."1.29Intestinal permeability changes in response to acetylsalicylic acid in relatives of patients with Crohn's disease. ( Hilsden, RJ; Meddings, JB; Sutherland, LR, 1996)
"One patient had ulcerative colitis, while two patients had Crohn's disease."1.27Pleuropericarditis: an extraintestinal complication of inflammatory bowel disease. Report of three cases and review of literature. ( Brewster, AC; Darrah, JJ; Heilpern, RJ; Patwardhan, RV, 1983)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199010 (25.00)18.7374
1990's4 (10.00)18.2507
2000's15 (37.50)29.6817
2010's8 (20.00)24.3611
2020's3 (7.50)2.80

Authors

AuthorsStudies
Cheemalavagu, S1
McCoy, SS1
Knight, JS1
Mak, JWY1
So, J1
Tang, W1
Yip, TCF1
Leung, WK1
Li, M1
Lo, FH1
Ng, KM1
Sze, SF1
Leung, CM1
Tsang, SWC1
Shan, EHS1
Chan, KH1
Lam, BCY1
Hui, AJ1
Chow, WH1
Chan, FKL1
Ng, SC1
Patel, P1
Gao, G1
Gulotta, G1
Dalal, S1
Cohen, RD1
Sakuraba, A1
Rubin, DT1
Pekow, J1
Keita, ÅV1
Lindqvist, CM1
Öst, Å1
Magana, CDL1
Schoultz, I1
Halfvarson, J1
Monif, GRG1
Prescott, D1
McKay, DM1
Yazıcı, HU1
Birdane, A1
Nadiradze, A1
Ünalır, A1
Chan, SS1
Luben, R1
Bergmann, MM1
Boeing, H1
Olsen, A1
Tjonneland, A1
Overvad, K1
Kaaks, R1
Kennedy, H1
Khaw, KT1
Riboli, E1
Hart, AR1
Kusunoki, R1
Ishihara, S1
Sato, M1
Sumita, Y1
Mishima, Y1
Okada, M1
Tada, Y1
Oka, A1
Fukuba, N1
Oshima, N1
Moriyama, I1
Yuki, T1
Sato, S1
Amano, Y1
Murakawa, Y1
Kinoshita, Y1
Yi, F1
Xia, B1
Ananthakrishnan, AN1
Higuchi, LM1
Huang, ES1
Khalili, H1
Richter, JM1
Fuchs, CS1
Chan, AT1
Martínez, JG1
Saus, C1
Morey, A1
Alarcón, A1
Bischoff, A1
Schölmerich, J1
Stange, EF1
CHANOINE, F2
DAVID, D1
Vogt, W1
Paraskevopoulos, I1
Konstantinou, G1
Liatsos, C1
Raithel, M1
Baenkler, HW1
Naegel, A1
Buchwald, F1
Schultis, HW1
Backhaus, B1
Kimpel, S1
Koch, H1
Mach, K1
Hahn, EG1
Konturek, PC1
Takeuchi, K1
Smale, S1
Premchand, P1
Maiden, L1
Sherwood, R1
Thjodleifsson, B1
Bjornsson, E1
Bjarnason, I1
Cozzi, F1
Podswiadek, M1
Cardinale, G1
Oliviero, F1
Dani, L1
Sfriso, P1
Punzi, L1
Freilinger, T1
Riedel, E1
Holtmannspötter, M1
Dichgans, M1
Peters, N1
Fahrländer, H1
Patwardhan, RV1
Heilpern, RJ1
Brewster, AC1
Darrah, JJ1
Hilsden, RJ1
Meddings, JB1
Sutherland, LR1
Martínez Sempere, JF1
Aparicio Tormo, JR1
Moya García, MI1
Trigueros Mateos, M1
Casellas Valdé, JA1
Palazón Azorín, JM1
Bickston, SJ1
Cominelli, F1
Söderholm, JD1
Olaison, G1
Lindberg, E1
Hannestad, U1
Vindels, A1
Tysk, C1
Järnerot, G1
Sjödahl, R1
Bonner, GF1
Walczak, M1
Kitchen, L1
Bayona, M1
Marvisi, M1
Fornasari, G1
Campieri, M2
Geboes, K1
Dalle, I1
Smith, MS1
Barker, JD1
Soren, A1
Cooperman, EM1
Holman, RT1
Lanfranchi, GA1
Brignola, C1
Bazzochi, G1
Gionchetti, P1
Minguzzi, MR1
Adami, F1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Biologic Onset of Crohn's Disease: A Screening Study in First Degree Relatives[NCT03291743]38 participants (Actual)Interventional2017-02-10Terminated (stopped due to Death of Principal Investigator)
Dexamethasone Versus Methylprednisolone for the Treatment of Active Inflammatory Bowel Disease[NCT00152620]40 participants Interventional2004-06-30Terminated (stopped due to study completed)
Effect of High Omega-3 Fish Intake on Lipid Peroxidation[NCT01183520]30 participants (Actual)Interventional2010-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for aspirin and Colitis, Granulomatous

ArticleYear
Rare case of Takayasu's arteritis associated with Crohn's disease.
    Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:15

    Topics: Adolescent; Adult; Aortic Valve Insufficiency; Aspirin; Coronary Artery Bypass; Crohn Disease; Cyclo

2011
[Etiology and pathogenesis of inflammatory bowel diseases].
    Praxis, 2002, Nov-20, Volume: 91, Issue:47

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Co

2002
[Therapy of chronic inflammatory bowel diseases].
    Praxis, 2002, Nov-20, Volume: 91, Issue:47

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies,

2002
[Inflammatory bowel disease--diagnosis and therapy].
    Praxis, 2005, Feb-02, Volume: 94, Issue:5

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azathioprine; Colitis, Ul

2005
Inflammatory bowel disease: short- and long-term treatments.
    Disease-a-month : DM, 1998, Volume: 44, Issue:4

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents,

1998
[Is the lung a target organ in inflammatory bowel disease?].
    Recenti progressi in medicina, 2001, Volume: 92, Issue:12

    Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bronchial Diseases

2001
New steroids and new salicylates in inflammatory bowel disease: a critical appraisal.
    Gut, 2002, Volume: 50 Suppl 3

    Topics: Acute Disease; Aspirin; Beclomethasone; Budesonide; Colitis, Ulcerative; Crohn Disease; Drug Therapy

2002
Influence of treatment on morphological features of mucosal inflammation.
    Gut, 2002, Volume: 50 Suppl 3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Colitis, Ulcerative; Crohn Disease;

2002
Control of polyunsaturated acids in tissue lipids.
    Journal of the American College of Nutrition, 1986, Volume: 5, Issue:2

    Topics: Acrodermatitis; alpha-Linolenic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Child; Crohn Dis

1986

Trials

3 trials available for aspirin and Colitis, Granulomatous

ArticleYear
Significance of salicylate intolerance in diseases of the lower gastrointestinal tract.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56 Suppl 5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colitis, Ulcerative; Crohn Disease; Diet; Drug Hyp

2005
Mud-bath treatment in spondylitis associated with inflammatory bowel disease--a pilot randomised clinical trial.
    Joint bone spine, 2007, Volume: 74, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colitis, Ulcerative; Combined Modality Ther

2007
5-aminosalicylic acid for the treatment of inflammatory bowel diseases.
    Gastroenterology, 1985, Volume: 89, Issue:3

    Topics: Aspirin; Colitis, Ulcerative; Crohn Disease; Enema; Humans

1985

Other Studies

28 other studies available for aspirin and Colitis, Granulomatous

ArticleYear
Digital ischaemia secondary to adalimumab-induced antiphospholipid syndrome.
    BMJ case reports, 2020, Feb-09, Volume: 13, Issue:2

    Topics: Adalimumab; Anti-Inflammatory Agents; Antiphospholipid Syndrome; Aspirin; Crohn Disease; Female; Han

2020
Cancer risk and chemoprevention in Chinese inflammatory bowel disease patients: a population-based cohort study.
    Scandinavian journal of gastroenterology, 2020, Volume: 55, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; China; Cohort Studies; Colitis, Ulcerative;

2020
Daily Aspirin Use Does Not Impact Clinical Outcomes in Patients With Inflammatory Bowel Disease.
    Inflammatory bowel diseases, 2021, 01-19, Volume: 27, Issue:2

    Topics: Aspirin; Colitis, Ulcerative; Crohn Disease; Humans; Retrospective Studies

2021
Gut Barrier Dysfunction-A Primary Defect in Twins with Crohn's Disease Predominantly Caused by Genetic Predisposition.
    Journal of Crohn's & colitis, 2018, 11-09, Volume: 12, Issue:10

    Topics: Adult; Aspirin; Chelating Agents; Chromium Radioisotopes; Claudin-5; Crohn Disease; Diagnostic Techn

2018
The myth of autoimmunity.
    Medical hypotheses, 2018, Volume: 121

    Topics: Antibodies; Antigens; Aspirin; Autoimmune Diseases; Autoimmunity; Crohn Disease; Diabetes Mellitus,

2018
Aspirin-triggered lipoxin enhances macrophage phagocytosis of bacteria while inhibiting inflammatory cytokine production.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 301, Issue:3

    Topics: Aspirin; Class Ib Phosphatidylinositol 3-Kinase; Crohn Disease; Humans; Interleukin-1beta; Interleuk

2011
Late bare-metal stent thrombosis in a patient with Crohn's disease.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2011, Volume: 11, Issue:5

    Topics: Adult; Angioplasty, Balloon, Coronary; Aspirin; Clopidogrel; Crohn Disease; Humans; Male; Myocardial

2011
Aspirin in the aetiology of Crohn's disease and ulcerative colitis: a European prospective cohort study.
    Alimentary pharmacology & therapeutics, 2011, Volume: 34, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Colitis, Ulcerative;

2011
Aspirin use and development of inflammatory bowel disease: confounding or causation?
    Alimentary pharmacology & therapeutics, 2011, Volume: 34, Issue:11-12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colitis, Ulcerative; Crohn Disease; Female; Humans

2011
Aspirin, nonsteroidal anti-inflammatory drug use, and risk for Crohn disease and ulcerative colitis: a cohort study.
    Annals of internal medicine, 2012, Mar-06, Volume: 156, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colitis, Ulcerative; Crohn Disease; Female; Follow

2012
[Crohn's disease and renal amyloidosis. Acute renal failure].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2002, Volume: 22, Issue:4

    Topics: Acetaminophen; Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Amyloidosis; Analgesics, Non-Nar

2002
[Chronic inflammatory bowel diseases. Earlier transition to immunosuppressive drugs].
    MMW Fortschritte der Medizin, 2002, May-02, Volume: 144, Issue:18

    Topics: Antibodies, Monoclonal; Aspirin; Colitis, Ulcerative; Crohn Disease; Humans; Immunosuppressive Agent

2002
[Some cases of Crohn's disease; preliminary note and results of treatment by salicylic acid derivatives].
    Acta gastro-enterologica Belgica, 1958, Volume: 21, Issue:3

    Topics: Aspirin; Crohn Disease; Humans; Ileitis

1958
[Treatment of Crohn's disease with salicylate derivatives].
    Archives des maladies de l'appareil digestif et des maladies de la nutrition, 1961, Volume: 50

    Topics: Aspirin; Crohn Disease; Humans; Ileitis; Prednisone; Salicylates

1961
[CLINICAL CONTRIBUTION TO THE STUDY OF CROHN'S DISEASE].
    Archivio per le scienze mediche, 1964, Volume: 118

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aspirin; Corrinoids; Crohn Disease; Diagnosis,

1964
Desensitization treatment of an aspirin- and mesalamine-sensitive patient with Crohn's disease.
    Inflammatory bowel diseases, 2005, Volume: 11, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Crohn Disease; Desensitization, Immunologic

2005
Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006, Volume: 4, Issue:2

    Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Colitis, Ul

2006
[Chronic inflammatory bowel diseases. Proven and innovative in the treatment].
    MMW Fortschritte der Medizin, 2006, Jun-15, Volume: 148, Issue:24

    Topics: Administration, Oral; Administration, Rectal; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspi

2006
Ischemic stroke and peripheral arterial thromboembolism in a patient with Crohn's disease: a case presentation.
    Journal of the neurological sciences, 2008, Mar-15, Volume: 266, Issue:1-2

    Topics: Anticoagulants; Aspirin; Blood Cell Count; Blood Coagulation; Bone Marrow; Brain Ischemia; Crohn Dis

2008
[Azulfidine/Salazopyrin therapy during pregnancy].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1981, Volume: 19

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Colitis, Ulcerative; Crohn Disease; Female; Humans; I

1981
Pleuropericarditis: an extraintestinal complication of inflammatory bowel disease. Report of three cases and review of literature.
    Archives of internal medicine, 1983, Volume: 143, Issue:1

    Topics: Adult; Aspirin; Colitis, Ulcerative; Crohn Disease; Humans; Indomethacin; Male; Middle Aged; Pericar

1983
Intestinal permeability changes in response to acetylsalicylic acid in relatives of patients with Crohn's disease.
    Gastroenterology, 1996, Volume: 110, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Crohn Disease; Duodenum; Family Health; Fem

1996
[Esophageal Crohn's disease].
    Gastroenterologia y hepatologia, 1997, Volume: 20, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Crohn Dise

1997
Different intestinal permeability patterns in relatives and spouses of patients with Crohn's disease: an inherited defect in mucosal defence?
    Gut, 1999, Volume: 44, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Crohn Disease; Diseases in Twins; Env

1999
Tolerance of nonsteroidal antiinflammatory drugs in patients with inflammatory bowel disease.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colitis, Ulcerative; Crohn Disease; Drug Utilizati

2000
Granulomatous ileocolitis preceded by three years of pauciarticular arthritis.
    The American journal of gastroenterology, 1978, Volume: 69, Issue:3 Pt 1

    Topics: Arthritis, Juvenile; Aspirin; Child; Crohn Disease; Granuloma; Humans; Male; Prednisone; Sulfasalazi

1978
Dissociation of acetylsalicylic acid in blood and joint fluid.
    Scandinavian journal of rheumatology, 1977, Volume: 6, Issue:1

    Topics: Adult; Arthritis, Rheumatoid; Aspirin; Buffers; Crohn Disease; Delayed-Action Preparations; Focal In

1977
New uses for acetylsalicylic acid and other prostaglandin antagonists.
    Canadian Medical Association journal, 1977, Aug-20, Volume: 117, Issue:4

    Topics: Aspirin; Crohn Disease; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Humans; Infant, Newbor

1977