Page last updated: 2024-10-23

aspirin and Cognition Disorders

aspirin has been researched along with Cognition Disorders in 54 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"A total of 973 patients aged≥75 years with atrial fibrillation were recruited from primary care and randomly assigned to warfarin (n=488; target international normalized ratio, 2-3) or aspirin (n=485; 75 mg/d)."9.19Warfarin versus aspirin for prevention of cognitive decline in atrial fibrillation: randomized controlled trial (Birmingham Atrial Fibrillation Treatment of the Aged Study). ( Fitzmaurice, D; Fletcher, K; Hobbs, FD; Lip, GY; Mant, J; Mavaddat, N; Roalfe, A, 2014)
"This paper describes the rationale and design of the ENVIS-ion Study, which aims to determine whether low-dose aspirin reduces the development of white matter hyper-intense (WMH) lesions and silent brain infarction (SBI)."9.16Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion). ( Abhayaratna, WP; Budge, MM; Essex, R; Janke, A; Kam, A; Reid, CM; Storey, E; Tonkin, A; Wang, JJ; Wong, TY; Woods, R, 2012)
"To examine the association of cognitive impairment with platelet activation and reactive oxygen species and total homocysteine levels; and to assess the biochemical efficacy of treatment with aspirin and vitamin supplements in people at high risk of dementia."9.10Effect of vitamins and aspirin on markers of platelet activation, oxidative stress and homocysteine in people at high risk of dementia. ( Clarke, R; Harrison, G; Richards, S, 2003)
"This paper will examine how cerebral perfusion deficits in cocaine abusers may be a target for pharmacotherapy."8.80Pharmacotherapy of cerebral ischemia in cocaine dependence. ( Kosten, TR, 1998)
" The authors--in view of the increased neuroinflammatory reaction frequently observed during normal brain ageing--suggest the long-term use of "fatty aspirin", an association of DHA and/or NPD1 and aspirin (or nitroaspirin), to postpone, or prevent, the structural neurodegeneration of the brain."5.35Fatty aspirin: a new perspective in the prevention of dementia of Alzheimer's type? ( Bria, P; Di Gioia, A; Pomponi, M; Pomponi, MF, 2008)
"A total of 973 patients aged≥75 years with atrial fibrillation were recruited from primary care and randomly assigned to warfarin (n=488; target international normalized ratio, 2-3) or aspirin (n=485; 75 mg/d)."5.19Warfarin versus aspirin for prevention of cognitive decline in atrial fibrillation: randomized controlled trial (Birmingham Atrial Fibrillation Treatment of the Aged Study). ( Fitzmaurice, D; Fletcher, K; Hobbs, FD; Lip, GY; Mant, J; Mavaddat, N; Roalfe, A, 2014)
"This paper describes the rationale and design of the ENVIS-ion Study, which aims to determine whether low-dose aspirin reduces the development of white matter hyper-intense (WMH) lesions and silent brain infarction (SBI)."5.16Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion). ( Abhayaratna, WP; Budge, MM; Essex, R; Janke, A; Kam, A; Reid, CM; Storey, E; Tonkin, A; Wang, JJ; Wong, TY; Woods, R, 2012)
"Subjects consisted of 2312 men and women aged 50 to 80 years participating in the Aspirin for Asymptomatic Atherosclerosis Trial, all of whom were free of symptomatic cardiovascular disease at baseline."5.14Peripheral levels of fibrinogen, C-reactive protein, and plasma viscosity predict future cognitive decline in individuals without dementia. ( Deary, IJ; Fowkes, FG; Lowe, GD; Marioni, RE; Murray, GD; Price, JF; Rumley, A; Stewart, MC, 2009)
"3350 men and women aged over 50 participating in the aspirin for asymptomatic atherosclerosis trial."5.13Low dose aspirin and cognitive function in middle aged to elderly adults: randomised controlled trial. ( Butcher, I; Deary, IJ; Fowkes, FG; Murray, GD; Price, JF; Sandercock, P; Stewart, MC, 2008)
"To examine the association of cognitive impairment with platelet activation and reactive oxygen species and total homocysteine levels; and to assess the biochemical efficacy of treatment with aspirin and vitamin supplements in people at high risk of dementia."5.10Effect of vitamins and aspirin on markers of platelet activation, oxidative stress and homocysteine in people at high risk of dementia. ( Clarke, R; Harrison, G; Richards, S, 2003)
"To investigate whether low-dose aspirin (<300 mg/d) can influence the onset of cognitive impairment or dementia in observational studies and improve cognitive test scores in randomized controlled trials (RCTs) in participants without dementia."4.95Low-Dose Aspirin Use and Cognitive Function in Older Age: A Systematic Review and Meta-analysis. ( Carvalho, AF; Lin, PY; Maggi, S; Muller, C; Schofield, P; Solmi, M; Stubbs, B; Thompson, T; Tseng, PT; Veronese, N, 2017)
"This paper will examine how cerebral perfusion deficits in cocaine abusers may be a target for pharmacotherapy."4.80Pharmacotherapy of cerebral ischemia in cocaine dependence. ( Kosten, TR, 1998)
" Data were analysed from three community-dwelling populations of older persons (>50 years) in central Scotland: the Aspirin for Asymptomatic Atherosclerosis (AAA) Trial (n = 2,091), the Edinburgh Type 2 Diabetes Study (ET2DS, n = 1,066), and the Lothian Birth Cohort 1936 (LBC1936, n = 1,091)."3.77Genetic associations between fibrinogen and cognitive performance in three Scottish cohorts. ( Deary, IJ; Fowkes, FG; Gow, AJ; Harris, SE; Houlihan, LM; Lowe, GD; Luciano, M; Marioni, RE; Murray, GD; Price, JF; Rumley, A; Stewart, MC; Strachan, MW, 2011)
"Recent data indicate that patients with vascular dementia (VaD) show a cholinergic deficit."2.71Rivastigmine superior to aspirin plus nimodipine in subcortical vascular dementia: an open, 16-month, comparative study. ( Antonello, RM; Bava, A; Cazzato, G; Griggio, S; Moretti, R; Torre, P; Ukmar, M, 2004)
"For patients with a diagnosis of vascular dementia there is evidence that aspirin is widely prescribed - in one study, completed by geriatricians and psychiatrists in the UK, 80% of patients with cognitive impairment (with vascular risk factors) were prescribed aspirin."2.41Aspirin for vascular dementia. ( Orrell, M; Rands, G; Spector, A; Williams, PS, 2000)
"For patients with a diagnosis of vascular dementia there is evidence that aspirin is widely prescribed - in one study, completed by geriatricians and psychiatrists in the UK, 80% of patients with cognitive impairment (with vascular risk factors) were prescribed aspirin."2.41Aspirin for vascular dementia. ( Orrel, M; Rands, G; Spector, A; Williams, PS, 2000)
" A number of secondary analyses were performed, including lobe-specific analyses, subgroup analyses based on participants' overall risk of cerebrovascular disease, and a dose-response relationship analysis."1.46Chronic Use of Aspirin and Total White Matter Lesion Volume: Results from the Women's Health Initiative Memory Study of Magnetic Resonance Imaging Study. ( Ammann, E; Espeland, MA; Holcombe, A; Kelley, BJ; Manson, JE; Robinson, J; Wallace, R, 2017)
" The authors--in view of the increased neuroinflammatory reaction frequently observed during normal brain ageing--suggest the long-term use of "fatty aspirin", an association of DHA and/or NPD1 and aspirin (or nitroaspirin), to postpone, or prevent, the structural neurodegeneration of the brain."1.35Fatty aspirin: a new perspective in the prevention of dementia of Alzheimer's type? ( Bria, P; Di Gioia, A; Pomponi, M; Pomponi, MF, 2008)
"None experienced strokes or transient ischemic attacks."1.35Low incidence of neurologic events during long-term support with the HeartMate XVE left ventricular assist device. ( Dia, M; Gallagher, C; Silver, MA; Slaughter, MS; Sobieski, MA, 2008)
" Overall, we found no relation between regular aspirin use and cognitive decline, but long-term use of ibuprofen may be related to decreased rates of cognitive decline in older persons."1.35Anti-inflammatory agents and cognitive decline in a bi-racial population. ( Bennett, DA; Bienias, JL; Evans, DA; Grodstein, F; Skarupski, KA; Wilson, RS, 2008)
"Colitis was induced in rats by an enema containing 2,4,6-trinitrobenzen sulfonic acid."1.32Decrease in non-selective, non-sustained attention induced by a chronic visceral inflammatory state as a new pain evaluation in rats. ( Ardid, D; Eschalier, A; Etienne, M; Jourdan, D; Millecamps, M, 2004)
"Stroke is highly prevalent in long-term care."1.31Clinical correlates and drug treatment of residents with stroke in long-term care. ( Lapane, KL; Quilliam, BJ, 2001)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19905 (9.26)18.7374
1990's4 (7.41)18.2507
2000's21 (38.89)29.6817
2010's23 (42.59)24.3611
2020's1 (1.85)2.80

Authors

AuthorsStudies
Lai, SW1
Kuo, YH1
Liao, KF1
Veronese, N1
Stubbs, B1
Maggi, S1
Thompson, T1
Schofield, P1
Muller, C1
Tseng, PT1
Lin, PY1
Carvalho, AF1
Solmi, M1
Holcombe, A1
Ammann, E1
Espeland, MA1
Kelley, BJ2
Manson, JE1
Wallace, R1
Robinson, J1
Li, S1
Zhang, X1
Fang, Q1
Zhou, J1
Zhang, M1
Wang, H1
Chen, Y1
Xu, B1
Wu, Y1
Qian, L1
Xu, Y1
Douiri, A1
McKevitt, C1
Emmett, ES1
Rudd, AG1
Wolfe, CD1
Mavaddat, N2
Roalfe, A2
Fletcher, K2
Lip, GY2
Hobbs, FD2
Fitzmaurice, D2
Mant, J2
Zito, S1
Lattanzio, F1
Di Nisio, M1
Selim, MH1
Molina, CA1
Falcone, GJ1
Rosand, J1
Al-Shahi Salman, R1
Dennis, MS1
McClure, LA2
Unverzagt, FW1
Kissela, B1
Kleindorfer, D1
Howard, G2
Wadley, VG1
Wang, LP1
Zhang, XY1
Liu, N1
Ma, ZZ1
Fang, DS1
Price, JF3
Stewart, MC3
Deary, IJ3
Murray, GD3
Sandercock, P1
Butcher, I1
Fowkes, FG3
Eikelboom, JW1
O'Donnell, M1
Pomponi, M1
Di Gioia, A1
Bria, P1
Pomponi, MF1
Slaughter, MS1
Sobieski, MA1
Gallagher, C1
Dia, M1
Silver, MA1
Boncoraglio, GB1
Bodini, A1
Brambilla, C1
Corsini, E1
Carriero, MR1
Parati, EA1
Puccio, D1
Novo, G1
Baiamonte, V1
Nuccio, A1
Fazio, G1
Corrado, E1
Coppola, G1
Muratori, I1
Vernuccio, L1
Novo, S1
Marioni, RE2
Lowe, GD2
Rumley, A2
Wang, T1
Fu, FH1
Han, B1
Zhang, LM1
Zhang, XM1
Almeida, OP1
Alfonso, H1
Jamrozik, K1
Hankey, GJ1
Flicker, L1
He, L1
Chen, X1
Zhou, M1
Zhang, D1
Yang, J1
Yang, M1
Zhou, D1
Strachan, MW1
Luciano, M1
Houlihan, LM1
Gow, AJ1
Harris, SE1
Benavente, OR1
White, CL1
Pearce, L1
Pergola, P1
Roldan, A1
Benavente, MF1
Coffey, C1
Szychowski, JM1
Conwit, R1
Heberling, PA1
Bazan, C1
Vidal-Pergola, G1
Talbert, R1
Hart, RG1
Acelajado, MC1
Oparil, S1
Reid, CM1
Storey, E1
Wong, TY1
Woods, R1
Tonkin, A1
Wang, JJ1
Kam, A1
Janke, A1
Essex, R1
Abhayaratna, WP1
Budge, MM1
Zhang, SJ1
Xue, ZY1
Colloca, G1
Tosato, M1
Vetrano, DL1
Topinkova, E1
Fialova, D1
Gindin, J1
van der Roest, HG1
Landi, F1
Liperoti, R1
Bernabei, R1
Onder, G1
Lance, EI1
Sreenivasan, AK1
Zabel, TA1
Kossoff, EH1
Comi, AM1
Holinski, S1
Claus, B1
Barajas, T1
Neumann, K1
Uebelhack, R1
Konertz, W1
Brown, AF1
Mangione, CM1
Saliba, D1
Sarkisian, CA1
Kang, JH2
Grodstein, F3
Clarke, R1
Harrison, G1
Richards, S1
Bellelli, G1
Trabucchi, M1
Millecamps, M1
Etienne, M1
Jourdan, D1
Eschalier, A1
Ardid, D1
Moretti, R1
Torre, P1
Antonello, RM1
Cazzato, G1
Griggio, S1
Ukmar, M1
Bava, A1
McLaurin, EY1
Holliday, SL1
Williams, P1
Brey, RL1
Cook, N1
Manson, J1
Buring, JE1
Whalley, LJ1
Mowat, DH1
Prettyman, RJ1
Skarupski, KA1
Bienias, JL1
Wilson, RS1
Bennett, DA1
Evans, DA1
Porter, D1
Rockwood, K1
Ebly, E1
Hachinski, V1
Hogan, D1
Richards, M1
Meade, TW1
Peart, S1
Brennan, PJ1
Mann, AH1
Kosten, TR1
Williams, PS2
Spector, A2
Orrell, M1
Rands, G2
Orrel, M1
Quilliam, BJ1
Lapane, KL1
May, FE1
Moore, MT1
Stewart, RB1
Hale, WE1
de Groen, PC1
Gogoll, L1
Bentsen, P1
Hochrein, H1
Skiendzielewski, JJ1
Parrish, G1
Harrington, TM1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Secondary Prevention of Small Subcortical Strokes (SPS3) Trial[NCT00059306]Phase 33,020 participants (Actual)Interventional2003-02-28Completed
TEC4Home Stroke - Assessing the Feasibility of Home Telemonitoring Technology in Managing Hypertension Among Stroke/TIA Patients. Pilot Study at Vancouver Stroke Program in Collaboration With TEC4Home Heart Failure Team[NCT03712033]50 participants (Actual)Observational2018-03-01Completed
Aspirin in Reducing Events in the Elderly[NCT01038583]19,114 participants (Actual)Observational2010-01-31Active, not recruiting
Identifying and Overcoming Barriers to Diabetes Management in the Elderly: An Intervention Study[NCT01480804]48 participants (Actual)Interventional2006-11-30Completed
Identifying and Overcoming Barriers to Diabetes Management in the Elderly: A Cost-effective Intervention Study[NCT01486290]52 participants (Actual)Interventional2007-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for aspirin and Cognition Disorders

ArticleYear
Low-Dose Aspirin Use and Cognitive Function in Older Age: A Systematic Review and Meta-analysis.
    Journal of the American Geriatrics Society, 2017, Volume: 65, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cognition; Cognition Disorders; Dementia; Humans;

2017
Pharmacotherapy of cerebral ischemia in cocaine dependence.
    Drug and alcohol dependence, 1998, Jan-01, Volume: 49, Issue:2

    Topics: Aspirin; Brain; Brain Ischemia; Cerebrovascular Circulation; Cocaine; Cocaine-Related Disorders; Cog

1998
Aspirin for vascular dementia.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Aspirin; Cognition Disorders; Dementia, Vascular; Humans

2000
Aspirin for vascular dementia.
    The Cochrane database of systematic reviews, 2000, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cognition Disorders; Dementia, Vascular; Humans; R

2000

Trials

14 trials available for aspirin and Cognition Disorders

ArticleYear
Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke: a randomised controlled trial.
    Stroke and vascular neurology, 2017, Volume: 2, Issue:4

    Topics: Aged; Aspirin; Brain; China; Cognition; Cognition Disorders; Executive Function; Female; Ginkgo bilo

2017
Warfarin versus aspirin for prevention of cognitive decline in atrial fibrillation: randomized controlled trial (Birmingham Atrial Fibrillation Treatment of the Aged Study).
    Stroke, 2014, Volume: 45, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Anticoagulants; Aspirin; Atrial Fibrillation; Cognition Disorders; F

2014
Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia.
    Genetics and molecular research : GMR, 2015, May-11, Volume: 14, Issue:2

    Topics: Aged; Aspirin; Cerebellum; Cognition Disorders; Dementia; Drugs, Chinese Herbal; Female; Ginkgo bilo

2015
Low dose aspirin and cognitive function in middle aged to elderly adults: randomised controlled trial.
    BMJ (Clinical research ed.), 2008, Sep-01, Volume: 337

    Topics: Aged; Aspirin; Atherosclerosis; Cognition Disorders; Double-Blind Method; Drug Administration Schedu

2008
Peripheral levels of fibrinogen, C-reactive protein, and plasma viscosity predict future cognitive decline in individuals without dementia.
    Psychosomatic medicine, 2009, Volume: 71, Issue:8

    Topics: Aspirin; Atherosclerosis; Biomarkers; Blood Viscosity; C-Reactive Protein; Cognition Disorders; Exec

2009
Radix/rhizoma notoginseng extract (sanchitongtshu) for ischemic stroke: a randomized controlled study.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Apr-15, Volume: 18, Issue:6

    Topics: Activities of Daily Living; Aged; Aspirin; Brain Ischemia; Cognition Disorders; Double-Blind Method;

2011
The Secondary Prevention of Small Subcortical Strokes (SPS3) study.
    International journal of stroke : official journal of the International Stroke Society, 2011, Volume: 6, Issue:2

    Topics: Antihypertensive Agents; Aspirin; Clopidogrel; Cognition Disorders; Humans; Hypertension; Magnetic R

2011
The Secondary Prevention of Small Subcortical Strokes (SPS3) study.
    International journal of stroke : official journal of the International Stroke Society, 2011, Volume: 6, Issue:2

    Topics: Antihypertensive Agents; Aspirin; Clopidogrel; Cognition Disorders; Humans; Hypertension; Magnetic R

2011
The Secondary Prevention of Small Subcortical Strokes (SPS3) study.
    International journal of stroke : official journal of the International Stroke Society, 2011, Volume: 6, Issue:2

    Topics: Antihypertensive Agents; Aspirin; Clopidogrel; Cognition Disorders; Humans; Hypertension; Magnetic R

2011
The Secondary Prevention of Small Subcortical Strokes (SPS3) study.
    International journal of stroke : official journal of the International Stroke Society, 2011, Volume: 6, Issue:2

    Topics: Antihypertensive Agents; Aspirin; Clopidogrel; Cognition Disorders; Humans; Hypertension; Magnetic R

2011
Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion).
    BMC neurology, 2012, Feb-08, Volume: 12

    Topics: Aged; Aging; Aspirin; Australia; Brain Infarction; Cognition; Cognition Disorders; Double-Blind Meth

2012
Effect of Western medicine therapy assisted by Ginkgo biloba tablet on vascular cognitive impairment of none dementia.
    Asian Pacific journal of tropical medicine, 2012, Volume: 5, Issue:8

    Topics: Aged; Aspirin; Blood Flow Velocity; Cardiovascular Agents; Cerebrovascular Disorders; Cognition Diso

2012
Effect of vitamins and aspirin on markers of platelet activation, oxidative stress and homocysteine in people at high risk of dementia.
    Journal of internal medicine, 2003, Volume: 254, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Cognition Disorders; Dementia; Female; Folic Acid; Follow-Up Studi

2003
Rivastigmine superior to aspirin plus nimodipine in subcortical vascular dementia: an open, 16-month, comparative study.
    International journal of clinical practice, 2004, Volume: 58, Issue:4

    Topics: Aged; Aged, 80 and over; Aspirin; Carbamates; Cholinesterase Inhibitors; Cognition Disorders; Dement

2004
Low dose aspirin and cognitive function in the women's health study cognitive cohort.
    BMJ (Clinical research ed.), 2007, May-12, Volume: 334, Issue:7601

    Topics: Aged; Aspirin; Cardiovascular Diseases; Cognition Disorders; Cohort Studies; Health Status; Humans;

2007
Is there any evidence for a protective effect of antithrombotic medication on cognitive function in men at risk of cardiovascular disease? Some preliminary findings.
    Journal of neurology, neurosurgery, and psychiatry, 1997, Volume: 62, Issue:3

    Topics: Aged; Anticoagulants; Aspirin; Cardiovascular Diseases; Cognition; Cognition Disorders; Double-Blind

1997
Darvon and Darvon-N.
    The Medical letter on drugs and therapeutics, 1972, May-26, Volume: 14, Issue:11

    Topics: Administration, Oral; Adolescent; Aspirin; Brain; Clinical Trials as Topic; Cognition Disorders; Cos

1972

Other Studies

36 other studies available for aspirin and Cognition Disorders

ArticleYear
Aspirin in people with dementia.
    European journal of clinical pharmacology, 2021, Volume: 77, Issue:11

    Topics: Aspirin; Cognition Disorders; Dementia; Humans

2021
Chronic Use of Aspirin and Total White Matter Lesion Volume: Results from the Women's Health Initiative Memory Study of Magnetic Resonance Imaging Study.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017, Volume: 26, Issue:10

    Topics: Aged; Aged, 80 and over; Aspirin; Cognition Disorders; Female; Humans; Leukoencephalopathies; Linear

2017
Long-term effects of secondary prevention on cognitive function in stroke patients.
    Circulation, 2013, Sep-17, Volume: 128, Issue:12

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Aspirin; Cognition Disorders; Dipyridamole; Female

2013
Letter by Zito et Al regarding article, "warfarin versus aspirin for prevention of cognitive decline in atrial fibrillation: randomized controlled trial (Birmingham atrial fibrillation treatment of the aged study)".
    Stroke, 2014, Volume: 45, Issue:9

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Cognition Disorders; Female; Fibrinolytic Agents; Huma

2014
Response to letter regarding article, "warfarin versus aspirin for prevention of cognitive decline in atrial fibrillation: randomized controlled trial (birmingham atrial fibrillation treatment of the aged study)".
    Stroke, 2014, Volume: 45, Issue:9

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Cognition Disorders; Female; Fibrinolytic Agents; Huma

2014
Elderly and forgetful: is aspirin safe for you?
    Stroke, 2014, Volume: 45, Issue:10

    Topics: Aged, 80 and over; Aspirin; Cerebral Amyloid Angiopathy; Cerebral Hemorrhage; Cognition Disorders; C

2014
Aspirin should be discontinued after lobar intracerebral hemorrhage.
    Stroke, 2014, Volume: 45, Issue:10

    Topics: Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Cognition Disorders; Comorbidity; Female; Humans; I

2014
Antiplatelet therapy may be continued after intracerebral hemorrhage.
    Stroke, 2014, Volume: 45, Issue:10

    Topics: Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Cognition Disorders; Comorbidity; Female; Humans; I

2014
Regular aspirin use does not reduce risk of cognitive decline.
    Journal of the American Geriatrics Society, 2015, Volume: 63, Issue:2

    Topics: Aged; Aspirin; Cognition Disorders; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; St

2015
Using aspirin to prevent cognitive decline.
    BMJ (Clinical research ed.), 2008, Sep-01, Volume: 337

    Topics: Aspirin; Cognition Disorders; Humans; Neuroprotective Agents

2008
Fatty aspirin: a new perspective in the prevention of dementia of Alzheimer's type?
    Current Alzheimer research, 2008, Volume: 5, Issue:5

    Topics: Alzheimer Disease; Animals; Antioxidants; Aspirin; Cognition Disorders; Dementia; Disease Models, An

2008
Low incidence of neurologic events during long-term support with the HeartMate XVE left ventricular assist device.
    Texas Heart Institute journal, 2008, Volume: 35, Issue:3

    Topics: Adult; Aged; Aspirin; Brain Diseases, Metabolic; Cardiomyopathy, Dilated; Cause of Death; Cognition

2008
Aspirin resistance determined with PFA-100 does not predict new thrombotic events in patients with stable ischemic cerebrovascular disease.
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:3

    Topics: Aged; Aspirin; Cognition Disorders; Drug Resistance; Female; Follow-Up Studies; Hematologic Tests; H

2009
Atrial fibrillation and mild cognitive impairment: what correlation?
    Minerva cardioangiologica, 2009, Volume: 57, Issue:2

    Topics: Activities of Daily Living; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin;

2009
Long-term but not short-term aspirin treatment attenuates diabetes-associated learning and memory decline in mice.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2011, Volume: 119, Issue:1

    Topics: Acetylcholinesterase; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspiri

2011
Aspirin use, depression, and cognitive impairment in later life: the health in men study.
    Journal of the American Geriatrics Society, 2010, Volume: 58, Issue:5

    Topics: Aged; Aged, 80 and over; Aspirin; Cognition Disorders; Depression; Humans; Male

2010
Genetic associations between fibrinogen and cognitive performance in three Scottish cohorts.
    Behavior genetics, 2011, Volume: 41, Issue:5

    Topics: Aged; Aging; Aspirin; Atherosclerosis; Cognition; Cognition Disorders; Cohort Studies; Cross-Section

2011
Antiplatelet therapy for transient ischemic attack.
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Ischemia; Clopidogrel; Cognition Disorders;

2012
Inappropriate drugs in elderly patients with severe cognitive impairment: results from the shelter study.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Aged; Aged, 80 and over; Aspirin; Cholinesterase Inhibitors; Cognition Disorders; Cross-Sectional St

2012
Aspirin use in Sturge-Weber syndrome: side effects and clinical outcomes.
    Journal of child neurology, 2013, Volume: 28, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Cognition Disorders; Elec

2013
Cerebroprotective effect of preoperative dual antiplatelet therapy in patients undergoing coronary bypass surgery.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2014, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiopulmonary Bypass; Clopidogrel; Cognition; Cognition D

2014
Guidelines for improving the care of the older person with diabetes mellitus.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:5 Suppl Gu

    Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M

2003
Guidelines for improving the care of the older person with diabetes mellitus.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:5 Suppl Gu

    Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M

2003
Guidelines for improving the care of the older person with diabetes mellitus.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:5 Suppl Gu

    Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M

2003
Guidelines for improving the care of the older person with diabetes mellitus.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:5 Suppl Gu

    Topics: Accidental Falls; Aged; Aspirin; Cognition Disorders; Depression; Diabetes Complications; Diabetes M

2003
Regular use of nonsteroidal anti-inflammatory drugs and cognitive function in aging women.
    Neurology, 2003, May-27, Volume: 60, Issue:10

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroidal; Aspir

2003
The specificity of prescription patterns in secondary stroke prevention.
    Journal of neurology, neurosurgery, and psychiatry, 2004, Volume: 75, Issue:3

    Topics: Accidental Falls; Anticoagulants; Aspirin; Cognition Disorders; Geriatric Assessment; Humans; Patien

2004
Decrease in non-selective, non-sustained attention induced by a chronic visceral inflammatory state as a new pain evaluation in rats.
    Pain, 2004, Volume: 109, Issue:3

    Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Attention; Behavior, Animal;

2004
Predictors of cognitive dysfunction in patients with systemic lupus erythematosus.
    Neurology, 2005, Jan-25, Volume: 64, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antiphospholipid; Aspirin; Autoant

2005
Aspirin and cognitive function.
    BMJ (Clinical research ed.), 2007, May-12, Volume: 334, Issue:7601

    Topics: Aged; Aspirin; Cardiovascular Diseases; Cognition Disorders; Humans; Nootropic Agents

2007
Too little, too late?
    BMJ (Clinical research ed.), 2007, May-26, Volume: 334, Issue:7603

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cognition Disorders; Humans; Nootropic Agents

2007
Anti-inflammatory agents and cognitive decline in a bi-racial population.
    Neuroepidemiology, 2008, Volume: 30, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Black People; Chic

2008
Drug induced confusional state.
    The New Zealand medical journal, 1982, Jul-28, Volume: 95, Issue:712

    Topics: Aged; Amitriptyline; Aspirin; Cognition Disorders; Confusion; Drug Interactions; Female; Humans; Sub

1982
Presence and treatment of vascular risk factors in patients with vascular cognitive impairment.
    Archives of neurology, 1997, Volume: 54, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspirin; Cognition Disorders; Dementia; Diabetes Complic

1997
Clinical correlates and drug treatment of residents with stroke in long-term care.
    Stroke, 2001, Volume: 32, Issue:6

    Topics: Aged; Aged, 80 and over; Aspirin; Cognition Disorders; Comorbidity; Cross-Sectional Studies; Databas

2001
Lack of association of nonsteroidal anti-inflammatory drug use and cognitive decline in the elderly.
    Gerontology, 1992, Volume: 38, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cognition Disorders; Fema

1992
[Chronic poisoning due to salicylic acid compounds: frequently not diagnosed or treated wrong].
    Nederlands tijdschrift voor geneeskunde, 1989, Jul-29, Volume: 133, Issue:30

    Topics: Acidosis; Aged; Aged, 80 and over; Alkalosis, Respiratory; Aspirin; Cognition Disorders; Confusion;

1989
[Cerebral complications in chronic acetylsalicylic acid poisoning].
    Deutsche medizinische Wochenschrift (1946), 1989, Feb-03, Volume: 114, Issue:5

    Topics: Aspirin; Chronic Disease; Cognition Disorders; Coma; Combined Modality Therapy; Consciousness Disord

1989
Mental confusion in an elderly, chronically ill patient.
    Annals of emergency medicine, 1986, Volume: 15, Issue:5

    Topics: Aged; Aspirin; Chronic Disease; Cognition Disorders; Confusion; Emergencies; Female; Humans; Renal D

1986