aspirin has been researched along with Cocarcinogenesis in 5 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Cocarcinogenesis: The combination of two or more different factors in the production of cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These occurred only in the groups given MNNG in combination with stress, aspirin, or sodium taurocholate, and did not occur in experimental groups given either MNNG, stress, aspirin, or sodium taurocholate alone, and did not occur in the control group." | 5.27 | Experimental models for gastric leiomyosarcoma. The effects of N-methyl-N'-nitro-N-nitrosoguanidine in combination with stress, aspirin, or sodium taurocholate. ( Cohen, A; Geller, SA; Horowitz, I; Toth, LS; Werther, JL, 1984) |
| " These occurred only in the groups given MNNG in combination with stress, aspirin, or sodium taurocholate, and did not occur in experimental groups given either MNNG, stress, aspirin, or sodium taurocholate alone, and did not occur in the control group." | 1.27 | Experimental models for gastric leiomyosarcoma. The effects of N-methyl-N'-nitro-N-nitrosoguanidine in combination with stress, aspirin, or sodium taurocholate. ( Cohen, A; Geller, SA; Horowitz, I; Toth, LS; Werther, JL, 1984) |
| "Aspirin is an inhibitor of prostaglandin H synthase and has been shown to inhibit FANFT-induced bladder carcinogenesis when coadministered in the diet." | 1.27 | Inhibition by aspirin of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide initiation and sodium saccharin promotion of urinary bladder carcinogenesis in male F344 rats. ( Cohen, SM; Hasegawa, R; Johansson, SL; Sakata, T; Zenser, TV, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pandeya, N | 1 |
| Webb, PM | 1 |
| Sadeghi, S | 1 |
| Green, AC | 1 |
| Whiteman, DC | 1 |
| Chang, TH | 1 |
| Lee, YC | 1 |
| Lee, KY | 1 |
| Sun, CH | 1 |
| Chang, YP | 1 |
| Cohen, A | 1 |
| Geller, SA | 1 |
| Horowitz, I | 1 |
| Toth, LS | 1 |
| Werther, JL | 1 |
| Ma, J | 1 |
| Stampfer, MJ | 1 |
| Giovannucci, E | 1 |
| Artigas, C | 1 |
| Hunter, DJ | 1 |
| Fuchs, C | 1 |
| Willett, WC | 1 |
| Selhub, J | 1 |
| Hennekens, CH | 1 |
| Rozen, R | 1 |
| Sakata, T | 1 |
| Hasegawa, R | 1 |
| Johansson, SL | 1 |
| Zenser, TV | 1 |
| Cohen, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Folates in the Care of the Male Infertility[NCT01407432] | Phase 3 | 162 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for aspirin and Cocarcinogenesis
| Article | Year |
|---|---|
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; beta Carotene; Case-Control Studies; Coca | 1997 |
4 other studies available for aspirin and Cocarcinogenesis
| Article | Year |
|---|---|
Gastro-oesophageal reflux symptoms and the risks of oesophageal cancer: are the effects modified by smoking, NSAIDs or acid suppressants?
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 2010 |
Cocarcinogenic action of aspirin on gastric tumors induced by N-nitroso-N-methylnitroguanidine in rats.
Topics: Adenocarcinoma; Animals; Aspirin; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Humans; Male; | 1983 |
Experimental models for gastric leiomyosarcoma. The effects of N-methyl-N'-nitro-N-nitrosoguanidine in combination with stress, aspirin, or sodium taurocholate.
Topics: Adenocarcinoma; Animals; Aspirin; Cocarcinogenesis; Diet; Disease Models, Animal; Leiomyosarcoma; Ma | 1984 |
Inhibition by aspirin of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide initiation and sodium saccharin promotion of urinary bladder carcinogenesis in male F344 rats.
Topics: Animals; Aspirin; Body Weight; Cocarcinogenesis; FANFT; Hydrogen-Ion Concentration; Male; Rats; Rats | 1986 |