Page last updated: 2024-10-23

aspirin and Cirrhosis, Liver

aspirin has been researched along with Cirrhosis, Liver in 63 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Research Excerpts

ExcerptRelevanceReference
"Despite the overall association of aspirin on reduced hepatocellular carcinoma (HCC) risk, there have been few studies on its benefit according to specific clinical conditions among hepatitis B virus (HBV)-infected patients."8.12Clinical Indication of Aspirin Associated With Reduced Risk of Liver Cancer in Chronic Hepatitis B: A Nationwide Cohort Study. ( Ahn, SH; Kim, BK; Yoon, JH; Yun, B, 2022)
"This retrospective multicenter study provides first data indicating a beneficial effect of aspirin on transplant-free survival after TIPS implantation in patients with refractory ascites."8.12Aspirin improves transplant-free survival after TIPS implantation in patients with refractory ascites: a retrospective multicentre cohort study. ( Bettinger, D; Gu, W; Heinzow, H; Huber, JP; Jansen, C; Köhler, M; Maschmeier, M; Masthoff, M; Meyer, C; Praktiknjo, M; Schindler, P; Schmidt, HH; Schoster, M; Schultheiss, M; Seifert, LL; Seifert, QE; Sturm, L; Trebicka, J; Weller, JF; Wildgruber, M; Wilms, C, 2022)
"Aspirin therapy has been associated with reduced risk of colon cancer, but there is only limited evidence for its effects on risk of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC)."7.96Association of Daily Aspirin Therapy With Hepatocellular Carcinoma Risk in Patients With Chronic Hepatitis C Virus Infection. ( Hsu, YC; Lee, TY; Lin, JT; Tseng, HC; Wu, CY; Wu, MS, 2020)
"Aspirin use may have chemo-preventive effect on recurrence of hepatitis B virus-related HCC after curative resection."7.96Aspirin is associated with low recurrent risk in hepatitis B virus-related hepatocellular carcinoma patients after curative resection. ( Chao, Y; Chau, GY; Hou, MC; Huang, YH; Huo, TI; Lee, IC; Lee, MH; Lin, HC; Su, CW; Yeh, YC; Young, SH, 2020)
"The effect of aspirin on the risk of hepatocellular carcinoma (HCC) remains unclear."7.88Aspirin Use and Risk of Hepatocellular Carcinoma in a National Cohort Study of Korean Adults. ( Chang, J; Hwang, IC; Kim, K; Park, SM, 2018)
"For aspirin, the RR was 1."5.91Effects of statins and aspirin on HCC risk in alcohol-related cirrhosis: nationwide emulated trials. ( Christensen, DH; Eiset, AH; Jepsen, P; Kraglund, F; Villadsen, GE; West, J, 2023)
"Aspirin use was associated with reduced risks of HCC and liver-associated mortality in adults with CHB."5.72Aspirin use and risk of hepatocellular carcinoma in patients with chronic hepatitis B with or without cirrhosis. ( Cho, EJ; Chung, JW; Jang, H; Kim, YJ; Lee, J; Lee, JH; Lee, YB; Moon, H; Nam, JY; Yoon, JH; Yu, SJ, 2022)
"Despite the overall association of aspirin on reduced hepatocellular carcinoma (HCC) risk, there have been few studies on its benefit according to specific clinical conditions among hepatitis B virus (HBV)-infected patients."4.12Clinical Indication of Aspirin Associated With Reduced Risk of Liver Cancer in Chronic Hepatitis B: A Nationwide Cohort Study. ( Ahn, SH; Kim, BK; Yoon, JH; Yun, B, 2022)
"This retrospective multicenter study provides first data indicating a beneficial effect of aspirin on transplant-free survival after TIPS implantation in patients with refractory ascites."4.12Aspirin improves transplant-free survival after TIPS implantation in patients with refractory ascites: a retrospective multicentre cohort study. ( Bettinger, D; Gu, W; Heinzow, H; Huber, JP; Jansen, C; Köhler, M; Maschmeier, M; Masthoff, M; Meyer, C; Praktiknjo, M; Schindler, P; Schmidt, HH; Schoster, M; Schultheiss, M; Seifert, LL; Seifert, QE; Sturm, L; Trebicka, J; Weller, JF; Wildgruber, M; Wilms, C, 2022)
"Aspirin therapy has been associated with reduced risk of colon cancer, but there is only limited evidence for its effects on risk of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC)."3.96Association of Daily Aspirin Therapy With Hepatocellular Carcinoma Risk in Patients With Chronic Hepatitis C Virus Infection. ( Hsu, YC; Lee, TY; Lin, JT; Tseng, HC; Wu, CY; Wu, MS, 2020)
"Aspirin use may have chemo-preventive effect on recurrence of hepatitis B virus-related HCC after curative resection."3.96Aspirin is associated with low recurrent risk in hepatitis B virus-related hepatocellular carcinoma patients after curative resection. ( Chao, Y; Chau, GY; Hou, MC; Huang, YH; Huo, TI; Lee, IC; Lee, MH; Lin, HC; Su, CW; Yeh, YC; Young, SH, 2020)
"The effect of aspirin on the risk of hepatocellular carcinoma (HCC) remains unclear."3.88Aspirin Use and Risk of Hepatocellular Carcinoma in a National Cohort Study of Korean Adults. ( Chang, J; Hwang, IC; Kim, K; Park, SM, 2018)
"96) as well as history of hematemesis, melena in the past 30 days, positive nasogastric aspirate, prior upper gastrointestinal bleeding or use of aspirin or non-steroidal anti-inflammatory."3.83Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics. ( Camus, M; Dulai, GS; Ghassemi, KA; Jensen, DM; Jutabha, R; Khungar, V; Kovacs, TO; Machicado, GA; Ohning, GV, 2016)
" The dog had a history of hypothyroidism, which was controlled with levothyroxine."3.72Portal vein and aortic thromboses in a Siberian husky with ehrlichiosis and hypothyroidism. ( Bressler, C; Himes, LC; Moreau, RE, 2003)
"Warfarin treatment was associated with better liver function protection and renal function improvement than aspirin treatment."2.90Warfarin versus aspirin prevents portal vein thrombosis after laparoscopic splenectomy and azygoportal disconnection: A randomized clinical trial. ( Bai, DS; Jiang, GQ; Jin, SJ; Qian, JJ; Xia, BL; Ye, J; Zhang, C, 2019)
"Aspirin may cause a transient shedding of renal tubular cells, alterations in urate excretion, inhibition of spironolactone action, and, in certain clinical settings, a reversible decline in renal function manifested as a fall in glomerular filtration that may be accompanied by mild water, sodium, and potassium retention."2.36Acute effects of aspirin and acetaminophen on renal function. ( Kimberly, RP; Plotz, PH, 1981)
"For aspirin, the RR was 1."1.91Effects of statins and aspirin on HCC risk in alcohol-related cirrhosis: nationwide emulated trials. ( Christensen, DH; Eiset, AH; Jepsen, P; Kraglund, F; Villadsen, GE; West, J, 2023)
"Aspirin use was associated with reduced risks of HCC and liver-associated mortality in adults with CHB."1.72Aspirin use and risk of hepatocellular carcinoma in patients with chronic hepatitis B with or without cirrhosis. ( Cho, EJ; Chung, JW; Jang, H; Kim, YJ; Lee, J; Lee, JH; Lee, YB; Moon, H; Nam, JY; Yoon, JH; Yu, SJ, 2022)
"Aspirin (30 mg/kg) was administered to rats by gavage once every morning over a period of 8 weeks."1.72Aspirin attenuates liver fibrosis by suppressing TGF‑β1/Smad signaling. ( Hu, X; Jiang, X; Liu, B; Sun, Y; Xiang, J; Xiao, B; Xie, J, 2022)
"Animals without steatosis (ie NAFLD) at week 16 were excluded from the data analysis."1.62The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non-alcoholic steatohepatitis. ( Andersen, M; Buelund, LE; Ipsen, DH; Latta, M; Lintrup, K; Lykkesfeldt, J; Skaarup, R; Skat-Rørdam, J; Svenningsen, M; Tveden-Nyborg, P, 2021)
"Aspirin is a non-steroidal anti-inflammatory drug used to relieve both inflammatory symptoms and pain."1.56Aspirin alleviates hepatic fibrosis by suppressing hepatic stellate cells activation via the TLR4/NF-κB pathway. ( Duan, L; Jia, Y; Liu, Y; Lu, Y; Nong, L; Tan, A; Zhao, J, 2020)
"The degree of liver fibrosis was determined using four validated fibrosis indices and a composite index."1.43Aspirin use is associated with lower indices of liver fibrosis among adults in the United States. ( Afdhal, N; Feldbrügge, L; Ghaziani, T; Jiang, ZG; Mukamal, KJ; Popov, Y; Robson, SC; Tapper, EB, 2016)
"Liver fibrosis was assessed by histological evaluation."1.40Aspirin may reduce liver fibrosis progression: Evidence from a multicenter retrospective study of recurrent hepatitis C after liver transplantation. ( Boëlle, PY; Chazouillères, O; Conti, F; Corpechot, C; Durand, F; Duvoux, C; Mackiewicz, V; Paradis, V; Poujol-Robert, A; Poupon, R; Wendum, D, 2014)
"MOR8457 also reduced liver fibrosis in mice placed on DDC-supplemented diets."1.40Extrahepatic platelet-derived growth factor-β, delivered by platelets, promotes activation of hepatic stellate cells and biliary fibrosis in mice. ( Arch, RH; Chung, J; Ikenaga, N; Kim, YO; Liu, SB; Miyamoto, M; Ogawa, S; Peng, ZW; Popov, Y; Schuppan, D; Sverdlov, DY; Yoshida, S, 2014)
"The gastric toxic effects of aspirin (ASA) and NCX-4016, a nitric oxide (NO)-releasing ASA, were compared in normal, cirrhotic, and arthritic rats."1.31Low gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in rats with cirrhosis and arthritis. ( Kato, S; Komoike, Y; Suzuki, K; Takeuchi, K; Ukawa, H, 2001)
"Acute bleeding from oesophageal varices is a major complication of cirrhosis of the liver."1.30Anti-inflammatory drugs and variceal bleeding: a case-control study. ( Beauchant, M; Becker, MC; Bernard, P; De Lédinghen, V; Fourdan, O; Gourlaouen, A; Heresbach, D; Ingrand, P; Liebaert-Bories, MP; Nousbaum, JB; Ribard, D; Silvain, C, 1999)
"In 8 patients with liver cirrhosis who underwent hepatectomy, one patient with a prolonged T2 (260 secs) and a normal skin BT bled postoperatively, however, 3 patients with a prolonged skin BT (greater than 15 min) and a normal T2 had no hemorrhagic complications."1.27Clinical application of a new in vitro bleeding time device on surgical patients. ( Itoh, T; Kambayashi, J; Mori, T; Sakon, M; Tsujinaka, T; Uemura, Y, 1988)
"The charts of 238 patients with systemic lupus erythematosus (SLE) were reviewed."1.26The spectrum of liver disease in systemic lupus erythematosus. Report of 33 histologically-proved cases and review of the literature. ( Anuras, S; LaBrecque, DR; Runyon, BA, 1980)

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-199026 (41.27)18.7374
1990's2 (3.17)18.2507
2000's4 (6.35)29.6817
2010's18 (28.57)24.3611
2020's13 (20.63)2.80

Authors

AuthorsStudies
Jang, H1
Lee, YB1
Moon, H1
Chung, JW1
Nam, JY1
Cho, EJ1
Lee, JH2
Yu, SJ1
Kim, YJ1
Lee, J1
Yoon, JH2
Guidotti, LG1
La Vecchia, C1
Colombo, M1
Yun, B1
Ahn, SH1
Kim, BK1
Sun, Y1
Liu, B1
Xie, J1
Jiang, X1
Xiao, B1
Hu, X1
Xiang, J1
Seifert, LL1
Schindler, P1
Sturm, L1
Gu, W1
Seifert, QE1
Weller, JF1
Jansen, C1
Praktiknjo, M1
Meyer, C1
Schoster, M1
Wilms, C1
Maschmeier, M1
Schmidt, HH1
Masthoff, M1
Köhler, M1
Schultheiss, M1
Huber, JP1
Bettinger, D1
Trebicka, J1
Wildgruber, M1
Heinzow, H1
Li, Y2
Fu, X1
Liu, P1
Liu, S1
Pan, Y1
Kraglund, F1
Christensen, DH1
Eiset, AH1
Villadsen, GE1
West, J1
Jepsen, P1
Du, ZQ1
Zhao, JZ1
Dong, J1
Bi, JB1
Ren, YF1
Zhang, J1
Khalid, B1
Wu, Z1
Lv, Y1
Zhang, XF1
Wu, RQ1
Severo, MD1
Liu, Y2
Nong, L1
Jia, Y1
Tan, A1
Duan, L1
Lu, Y1
Zhao, J1
Lee, TY1
Hsu, YC1
Tseng, HC1
Lin, JT1
Wu, MS1
Wu, CY1
Ipsen, DH1
Skat-Rørdam, J1
Svenningsen, M1
Andersen, M1
Latta, M1
Buelund, LE1
Lintrup, K1
Skaarup, R1
Lykkesfeldt, J1
Tveden-Nyborg, P1
Ren, T1
Xu, X1
Jin, J1
Ponzetto, A1
Figura, N1
Feagins, LA1
Wan, YM1
Li, YH1
Wu, HM1
Xu, ZY1
Xu, Y1
Yang, LH1
Wu, XN1
Yang, JH1
Hwang, IC1
Chang, J1
Kim, K1
Park, SM1
Patel, SS1
Guzman, LA1
Lin, FP1
Pence, T1
Reichman, T1
John, B1
Celi, FS1
Liptrap, E1
Bhati, C1
Siddiqui, MS1
VanWagner, LB1
So, S1
Ahn, JY1
Kim, N1
Na, HK1
Jung, KW1
Kim, DH1
Choi, KD1
Song, HJ1
Lee, GH1
Jung, HY1
Bai, DS2
Xia, BL2
Zhang, C1
Ye, J1
Qian, JJ2
Jin, SJ2
Jiang, GQ2
Simon, TG1
Henson, J1
Osganian, S1
Masia, R1
Chan, AT1
Chung, RT1
Corey, KE1
Young, SH1
Chau, GY1
Lee, IC1
Yeh, YC1
Chao, Y1
Huo, TI1
Su, CW1
Lin, HC1
Hou, MC1
Lee, MH1
Huang, YH1
Vilar-Gomez, E1
Chalasani, N1
Poujol-Robert, A1
Boëlle, PY1
Conti, F1
Durand, F1
Duvoux, C1
Wendum, D1
Paradis, V1
Mackiewicz, V1
Chazouillères, O1
Corpechot, C1
Poupon, R1
Yoshida, S1
Ikenaga, N1
Liu, SB1
Peng, ZW1
Chung, J1
Sverdlov, DY1
Miyamoto, M1
Kim, YO1
Ogawa, S1
Arch, RH1
Schuppan, D1
Popov, Y2
Jiang, ZG1
Feldbrügge, L1
Tapper, EB1
Ghaziani, T1
Afdhal, N1
Robson, SC1
Mukamal, KJ1
Chen, P1
Zuo, SQ1
Camus, M1
Khungar, V1
Jensen, DM1
Ohning, GV1
Kovacs, TO1
Jutabha, R1
Ghassemi, KA1
Machicado, GA1
Dulai, GS1
Scharf, RE1
Pivalizza, EG1
Melnikov, V1
Guzman-Reyes, S1
Marasigan, B1
Russo, MW1
Pierson, J1
Narang, T1
Montegudo, A1
Eskind, L1
Gulati, S1
MENGUY, R3
Bressler, C1
Himes, LC1
Moreau, RE1
Füessl, HS1
Planas, R2
Arroyo, V3
Rimola, A3
Pérez-Ayuso, RM3
Rodés, J3
Gaya, J2
Deulofeu, R1
Rivera, F2
Camps, J1
Costa, J1
Dunn, MJ1
Plotz, PH1
Kimberly, RP1
Runyon, BA1
LaBrecque, DR1
Anuras, S1
D'Abrigeon, G1
Blanc, P1
Durand, L1
Larrey, D1
Michel, H1
De Lédinghen, V1
Heresbach, D1
Fourdan, O1
Bernard, P1
Liebaert-Bories, MP1
Nousbaum, JB1
Gourlaouen, A1
Becker, MC1
Ribard, D1
Ingrand, P1
Silvain, C1
Beauchant, M1
Kato, S1
Suzuki, K1
Ukawa, H1
Komoike, Y1
Takeuchi, K2
Damus, PS1
Wallace, GA1
Franco, D1
Durandy, Y1
Deporte, A1
Bismuth, H1
Couinaud, C1
Schirru, PL1
Okabe, S2
Urushidani, T1
Naganuma, T1
Takagi, K1
Tsujinaka, T1
Itoh, T1
Uemura, Y1
Sakon, M1
Kambayashi, J1
Mori, T1
Laffi, G1
La Villa, G1
Pinzani, M1
Ciabattoni, G1
Patrignani, P1
Mannelli, M1
Cominelli, F1
Gentilini, P1
Bernardi, P1
Ghezzi, F1
Bastagli, L1
Grimaldi, R1
Cavazza, M1
Minelli, C1
Fontana, F1
Clo', C1
Ventura, C1
Capelli, M1
Mannucci, PM1
Vicente, V1
Vianello, L1
Cattaneo, M1
Alberca, I1
Coccato, MP1
Faioni, E1
Mari, D1
Sahud, MA1
Desbaillets, L1
Masters, YF1
Minssart, F1
Lataste, J1
Le Picard, P1
Steinberg, AD1
Winckelmann, G1
Benhamou, JP1
Debray, C1
Hamburger, J1
Loygue, J1
Roux, M1
Pequignot, H1
Okumura, H1
Isoda, K1
Aramaki, T1
Ichikawa, T1
Fukuda, N1
Russell, AS1
Sturge, RA1
Smith, MA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sclerotherapy With Polidocanol Foam in the Treatment of First, Second and Third-Grade Hemorrhoidal Disease in Patients With Liver Cirrhosis: A Prospective, Cohort Trial[NCT05807425]Phase 2/Phase 340 participants (Anticipated)Interventional2023-03-31Recruiting
Video Capsule Endoscopy for Lesion Localization and Diagnosis in Patients With Severe Hematochezia[NCT03616041]50 participants (Anticipated)Observational2021-02-10Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for aspirin and Cirrhosis, Liver

ArticleYear
Association of aspirin and nonaspirin NSAIDs therapy with the incidence risk of hepatocellular carcinoma: a systematic review and meta-analysis on cohort studies.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2022, 01-01, Volume: 31, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Hepatocellular; Cohort Studies; Hepatit

2022
[Acquired platelet function disorders: pathogenesis, classification, frequency, diagnosis, clinical management].
    Hamostaseologie, 2008, Volume: 28, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelet Disorders; Blood Platelets; Coronar

2008
CURRENT CONCEPTS OF THE ETIOLOGY OF DUODENAL ULCER.
    The American journal of digestive diseases, 1964, Volume: 9

    Topics: Adrenal Cortex Hormones; Aspirin; Caffeine; Duodenal Ulcer; Gastric Juice; Gastric Mucosa; Genetics,

1964
Acute effects of aspirin and acetaminophen on renal function.
    Archives of internal medicine, 1981, Feb-23, Volume: 141, Issue:3 Spec No

    Topics: Acetaminophen; Aspirin; Humans; Indomethacin; Kidney; Kidney Failure, Chronic; Liver Cirrhosis; Lupu

1981
Platelet disorders: a review of disturbances in adhesion, aggregation, and release reaction.
    California medicine, 1972, Volume: 116, Issue:1

    Topics: Adenosine Diphosphate; Afibrinogenemia; Anemia; Aspirin; Blood Platelet Disorders; Connective Tissue

1972
An approach to the use of immunosuppressive drugs in nonmalignant diseases.
    The Journal of allergy and clinical immunology, 1973, Volume: 52, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chlorambucil; Cyclophosphamide; G

1973
[Blood platelet diseases].
    Medizinische Klinik, 1973, Jan-12, Volume: 68, Issue:2

    Topics: Adenosine Diphosphate; Afibrinogenemia; Aspirin; Blood Platelet Disorders; Blood Platelets; Diagnosi

1973

Trials

3 trials available for aspirin and Cirrhosis, Liver

ArticleYear
Warfarin versus aspirin prevents portal vein thrombosis after laparoscopic splenectomy and azygoportal disconnection: A randomized clinical trial.
    International journal of surgery (London, England), 2019, Volume: 64

    Topics: Aged; Aged, 80 and over; Aspirin; Female; Humans; Incidence; Laparoscopy; Liver Cirrhosis; Male; Mid

2019
Anticoagulation Therapy with Warfarin Versus Low-Dose Aspirin Prevents Portal Vein Thrombosis After Laparoscopic Splenectomy and Azygoportal Disconnection.
    Journal of laparoendoscopic & advanced surgical techniques. Part A, 2016, Volume: 26, Issue:7

    Topics: Adolescent; Adult; Aged; Anticoagulants; Aspirin; Azygos Vein; Female; Heparin, Low-Molecular-Weight

2016
Controlled trial of desmopressin in liver cirrhosis and other conditions associated with a prolonged bleeding time.
    Blood, 1986, Volume: 67, Issue:4

    Topics: Adolescent; Adult; Aged; Aspirin; Bleeding Time; Clinical Trials as Topic; Deamino Arginine Vasopres

1986

Other Studies

53 other studies available for aspirin and Cirrhosis, Liver

ArticleYear
Aspirin use and risk of hepatocellular carcinoma in patients with chronic hepatitis B with or without cirrhosis.
    Hepatology (Baltimore, Md.), 2022, Volume: 76, Issue:2

    Topics: Adult; Antiviral Agents; Aspirin; Carcinoma, Hepatocellular; Hepatitis B, Chronic; Humans; Incidence

2022
Low-dose aspirin reduces the risk of HBV-associated HCC even when administered short-term: Too good to be true?
    Hepatology (Baltimore, Md.), 2022, Volume: 76, Issue:2

    Topics: Aspirin; Carcinoma, Hepatocellular; Hepatitis B virus; Humans; Liver Cirrhosis; Liver Neoplasms; Ris

2022
Clinical Indication of Aspirin Associated With Reduced Risk of Liver Cancer in Chronic Hepatitis B: A Nationwide Cohort Study.
    The American journal of gastroenterology, 2022, 05-01, Volume: 117, Issue:5

    Topics: Aspirin; Carcinoma, Hepatocellular; Cohort Studies; Female; Hepatitis B virus; Hepatitis B, Chronic;

2022
Aspirin attenuates liver fibrosis by suppressing TGF‑β1/Smad signaling.
    Molecular medicine reports, 2022, Volume: 25, Issue:5

    Topics: Animals; Aspirin; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Rats; Rats, Sprague-Dawley

2022
Aspirin improves transplant-free survival after TIPS implantation in patients with refractory ascites: a retrospective multicentre cohort study.
    Hepatology international, 2022, Volume: 16, Issue:3

    Topics: Ascites; Aspirin; Cohort Studies; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Human

2022
Early prevention and risk factors analysis of portal vein system thrombosis after laparoscopic splenectomy and pericardial devascularization.
    Surgical endoscopy, 2022, Volume: 36, Issue:12

    Topics: Anticoagulants; Aspirin; Humans; Hypertension, Portal; Laparoscopy; Liver Cirrhosis; Portal Vein; Ri

2022
Effects of statins and aspirin on HCC risk in alcohol-related cirrhosis: nationwide emulated trials.
    Hepatology communications, 2023, 01-01, Volume: 7, Issue:1

    Topics: Aspirin; Carcinoma, Hepatocellular; Fibrosis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors

2023
Effect of low-dose aspirin administration on long-term survival of cirrhotic patients after splenectomy: A retrospective single-center study.
    World journal of gastroenterology, 2019, Jul-28, Volume: 25, Issue:28

    Topics: Adult; Aged; Aspirin; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Female; Follow-Up

2019
Daily Aspirin Use Associated With Reduced Risk for Fibrosis Progression in Patients With Nonalcoholic Fatty Liver Disease.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2020, Volume: 18, Issue:2

    Topics: Aspirin; Disease Progression; Fibrosis; Humans; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease

2020
Aspirin alleviates hepatic fibrosis by suppressing hepatic stellate cells activation via the TLR4/NF-κB pathway.
    Aging, 2020, 04-13, Volume: 12, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Down-Regulation; Hepatic Stellate Cells;

2020
Association of Daily Aspirin Therapy With Hepatocellular Carcinoma Risk in Patients With Chronic Hepatitis C Virus Infection.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2020, Volume: 18, Issue:12

    Topics: Aged; Antiviral Agents; Aspirin; Carcinoma, Hepatocellular; Cohort Studies; Hepatitis C, Chronic; Hu

2020
The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non-alcoholic steatohepatitis.
    Basic & clinical pharmacology & toxicology, 2021, Volume: 128, Issue:4

    Topics: Animals; Aspirin; Diet, High-Fat; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Reposit

2021
Letter: bleeding in cirrhotics receiving coronary stenting and antiplatelet therapy.
    Alimentary pharmacology & therapeutics, 2017, Volume: 46, Issue:7

    Topics: Aspirin; Drug Therapy, Combination; Hemorrhage; Humans; Liver Cirrhosis; Platelet Aggregation Inhibi

2017
Letter: bleeding in cirrhotics receiving coronary stenting and antiplatelet therapy - author's reply.
    Alimentary pharmacology & therapeutics, 2017, Volume: 46, Issue:7

    Topics: Aspirin; Drug Therapy, Combination; Hemorrhage; Humans; Liver Cirrhosis; Platelet Aggregation Inhibi

2017
Portal vein thrombosis before and after transjugular intrahepatic portosystemic shunt placement: An observational study (STROBE compliant).
    Medicine, 2017, Volume: 96, Issue:45

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Clopidogrel; Female; Humans; Leukocyte Coun

2017
Aspirin Use and Risk of Hepatocellular Carcinoma in a National Cohort Study of Korean Adults.
    Scientific reports, 2018, 03-21, Volume: 8, Issue:1

    Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinogenesis; Carcinom

2018
Utilization of aspirin and statin in management of coronary artery disease in patients with cirrhosis undergoing liver transplant evaluation.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2018, Volume: 24, Issue:7

    Topics: Aged; Aspirin; Coronary Angiography; Coronary Artery Disease; Drug Therapy, Combination; Drug Utiliz

2018
Asprin and statin use for management of atherosclerotic cardiovascular disease in liver transplant candidates: Are we missing the mark?
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2018, Volume: 24, Issue:7

    Topics: Aspirin; Coronary Artery Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Cirr

2018
Comparison of the effects of antithrombotic therapy on delayed bleeding after gastric endoscopic resection: a propensity score-matched case-control study.
    Gastrointestinal endoscopy, 2019, Volume: 89, Issue:2

    Topics: Aged; Anticoagulants; Antithrombins; Aspirin; Case-Control Studies; Deprescriptions; Endoscopic Muco

2019
Daily Aspirin Use Associated With Reduced Risk For Fibrosis Progression In Patients With Nonalcoholic Fatty Liver Disease.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2019, Volume: 17, Issue:13

    Topics: Adult; Aged; Aspartate Aminotransferases; Aspirin; Cohort Studies; Disease Progression; Duration of

2019
Aspirin is associated with low recurrent risk in hepatitis B virus-related hepatocellular carcinoma patients after curative resection.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2020, Volume: 119, Issue:1 Pt 2

    Topics: Aged; alpha-Fetoproteins; Antiviral Agents; Aspirin; Carcinoma, Hepatocellular; Female; Hepatectomy;

2020
Daily Aspirin Use Reduces Risk of Fibrosis Progression in Patients With Nonalcoholic Fatty Liver Disease, Providing New Uses for an Old Drug.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2019, Volume: 17, Issue:13

    Topics: Aspirin; Disease Progression; Humans; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease

2019
Aspirin may reduce liver fibrosis progression: Evidence from a multicenter retrospective study of recurrent hepatitis C after liver transplantation.
    Clinics and research in hepatology and gastroenterology, 2014, Volume: 38, Issue:5

    Topics: Aspirin; Disease Progression; Female; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Transplan

2014
Extrahepatic platelet-derived growth factor-β, delivered by platelets, promotes activation of hepatic stellate cells and biliary fibrosis in mice.
    Gastroenterology, 2014, Volume: 147, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Aspirin;

2014
Aspirin use is associated with lower indices of liver fibrosis among adults in the United States.
    Alimentary pharmacology & therapeutics, 2016, Volume: 43, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Sectional Studies; Female; Hepatitis,

2016
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:9

    Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont

2016
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:9

    Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont

2016
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:9

    Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont

2016
Origin, Clinical Characteristics and 30-Day Outcomes of Severe Hematochezia in Cirrhotics and Non-cirrhotics.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:9

    Topics: Aged; Aged, 80 and over; Angiodysplasia; Aspirin; Blood Component Transfusion; California; Case-Cont

2016
Thrombelastograph platelet mapping in a patient receiving antiplatelet therapy.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2010, Volume: 16, Issue:7

    Topics: Aspirin; Blood Coagulation Disorders; Blood Platelets; Clopidogrel; Dose-Response Relationship, Drug

2010
Coronary artery stents and antiplatelet therapy in patients with cirrhosis.
    Journal of clinical gastroenterology, 2012, Volume: 46, Issue:4

    Topics: Aged; Aspirin; Clopidogrel; Coronary Artery Disease; Fatty Liver; Female; Follow-Up Studies; Gastroi

2012
[ETIOLOGY OF THE DUODENAL ULCER].
    Munchener medizinische Wochenschrift (1950), 1964, Mar-27, Volume: 106

    Topics: Aspirin; Caffeine; Disease Susceptibility; Duodenal Ulcer; Genetics, Medical; Humans; Hyperparathyro

1964
Portal vein and aortic thromboses in a Siberian husky with ehrlichiosis and hypothyroidism.
    The Journal of small animal practice, 2003, Volume: 44, Issue:9

    Topics: Animals; Aorta, Thoracic; Aspirin; Diagnosis, Differential; Dog Diseases; Dogs; Doxycycline; Ehrlich

2003
[Family practice highlights of stomach, liver and intestinal reference points. Your arsenal against abdominal problems].
    MMW Fortschritte der Medizin, 2007, Nov-29, Volume: 149, Issue:48

    Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Barrett Esophagus; Family Practi

2007
Acetylsalicylic acid suppresses the renal hemodynamic effect and reduces the diuretic action of furosemide in cirrhosis with ascites.
    Gastroenterology, 1983, Volume: 84, Issue:2

    Topics: Aspirin; Diuresis; Furosemide; Glomerular Filtration Rate; Humans; Kidney; Liver Cirrhosis; Liver Ci

1983
Sympathetic nervous activity, renin-angiotensin system and renal excretion of prostaglandin E2 in cirrhosis. Relationship to functional renal failure and sodium and water excretion.
    European journal of clinical investigation, 1983, Volume: 13, Issue:3

    Topics: Ascites; Aspirin; Dinoprostone; Diuresis; Glomerular Filtration Rate; Humans; Kidney Diseases; Liver

1983
Evidence that renal prostaglandins are involved in renal water metabolism in cirrhosis.
    Kidney international, 1984, Volume: 26, Issue:1

    Topics: Arginine Vasopressin; Aspirin; Body Water; Depression, Chemical; Dinoprostone; Female; Glomerular Fi

1984
Role of eicosanoids in the control of renal function in severe hepatic disease.
    Gastroenterology, 1984, Volume: 87, Issue:6

    Topics: Animals; Arachidonic Acids; Aspirin; Dogs; Humans; Ibuprofen; Indomethacin; Kidney; Lipoxygenase; Li

1984
The spectrum of liver disease in systemic lupus erythematosus. Report of 33 histologically-proved cases and review of the literature.
    The American journal of medicine, 1980, Volume: 69, Issue:2

    Topics: Adolescent; Adult; Aged; Aspirin; Biopsy; Chemical and Drug Induced Liver Injury; Child, Preschool;

1980
[Liver cirrhosis and granulomatous hepatitis after prolonged ingestion of lysine acetylsalicylate].
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:11

    Topics: Aged; Analgesics; Aspirin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug;

1995
Anti-inflammatory drugs and variceal bleeding: a case-control study.
    Gut, 1999, Volume: 44, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Esophageal and

1999
Low gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in rats with cirrhosis and arthritis.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Blood Flow Veloc

2001
Immunologic measurement of antithrombin III-heparin cofactor and alpha2 macroglobulin in disseminated intravascular coagulation and hepatic failure coagulopathy.
    Thrombosis research, 1975, Volume: 6, Issue:1

    Topics: Alpha-Globulins; Antithrombin III; Antithrombins; Aspirin; Blood Platelets; Chemical and Drug Induce

1975
Upper gastrointestinal haemorrhage in hepatic cirrhosis: causes and relation to hepatic failure and stress.
    Lancet (London, England), 1977, Jan-29, Volume: 1, Issue:8005

    Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aspirin; Chronic Disease; Esophagea

1977
[The effect of splenectomy on the platelet disorder of cirrhotics (author's transl)].
    Chirurgie; memoires de l'Academie de chirurgie, 1979, Volume: 105, Issue:5

    Topics: Aspirin; Blood Platelet Disorders; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Mal

1979
[Behaviour of "haemorrhage times" in hypocolinesterasic subjects after administration of acetil-salicylic acid (author's transl)].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1977, Volume: 13, Issue:1

    Topics: Aspirin; Blood Coagulation; Cholinesterases; Hemorrhage; Hepatitis; Humans; Liver Cirrhosis; Preoper

1977
Effects of L-glutamine on acetylsalicylic acid-induced gastric lesions in normal and cirrhotic rats.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:6

    Topics: Animals; Aspirin; Carbon Tetrachloride Poisoning; Gastrointestinal Hemorrhage; Glutamine; Intestinal

1975
Clinical application of a new in vitro bleeding time device on surgical patients.
    The Japanese journal of surgery, 1988, Volume: 18, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aspirin; Bleeding Time; Epoprostenol; Hemorrhage; Hemostasis; H

1988
Altered renal and platelet arachidonic acid metabolism in cirrhosis.
    Gastroenterology, 1986, Volume: 90, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Adult; Aged; Arachidonic Acid; Arachidonic Acids;

1986
Effects of polyunsaturated fatty acids and prostaglandin synthesis on renal function.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 22, Issue:2

    Topics: Aspirin; Body Water; Dinoprostone; Fatty Acids, Unsaturated; Heart Failure; Humans; Injections, Intr

1986
Abnormal aspirin metabolism in patients with cirrhosis and its possible relationship to bleeding in cirrhotics.
    Annals of surgery, 1972, Volume: 176, Issue:3

    Topics: Adult; Animals; Aspirin; Esterases; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Hyd

1972
[Blood coagulation disorders of a toxic (alcoholism, drugs, poisoning) or iatrogenic (anticoagulants) nature].
    Revue belge de medecine dentaire. Belgisch tijdschrift voor tandheelkunde, 1972, Volume: 27, Issue:2

    Topics: Alcoholic Intoxication; Analgesics; Anticoagulants; Aspirin; Blood Coagulation Disorders; Blood Coag

1972
[Upper digestive hemorrhages due to gastritis or of unknown cause. (Apropos of 140 cases)].
    Journal de chirurgie, 1973, Volume: 106, Issue:6

    Topics: Alcoholism; Aspirin; Endoscopy; Esophageal and Gastric Varices; Fiber Optic Technology; Gastrectomy;

1973
[Procedure to follow in case of severe hematemesis].
    La Presse medicale, 1969, Feb-22, Volume: 77, Issue:10

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aspirin; Blood Transfusion; Blood Volume Determin

1969
[Aspirin esterase activity test as a new liver function test].
    Saishin igaku. Modern medicine, 1971, Volume: 26, Issue:1

    Topics: Animals; Aspirin; Clinical Enzyme Tests; Esterases; Heart Failure; Hepatitis; Humans; Hypoxia; Liver

1971
Serum transaminases during salicylate therapy.
    British medical journal, 1971, May-22, Volume: 2, Issue:5759

    Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Alkaline Phosphatase; Arthritis, Juvenil

1971