aspirin has been researched along with Churg-Strauss Syndrome in 9 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Churg-Strauss Syndrome: Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Underlying conditions such as immune deficiency, Wegener's granulomatosis, Churg-Strauss syndrome, aspirin hypersensitivity and allergic fungal sinusitis may present as rhinosinusitis." | 3.74 | BSACI guidelines for the management of rhinosinusitis and nasal polyposis. ( Dixon, TA; Drake-Lee, AB; Durham, SR; Huber, PA; Jones, NS; Mirakian, R; Nasser, SM; Ryan, D; Scadding, GK, 2008) |
| "A 23-year-old male with bronchial asthma developed eosinophilia (eosinophils greater than 2,000/mm3) and was observed at our hospital." | 1.28 | [Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome]. ( Arai, Y; Fukushima, N; Isokane, N; Miyamoto, Y; Sano, Y; Suzuki, N, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Herzberg, SD | 1 |
| Bosso, AM | 1 |
| Sangal, NR | 1 |
| Bosso, JV | 1 |
| Ball, LL | 1 |
| Velasquez, SA | 1 |
| Al Jammal, OM | 1 |
| White, AA | 1 |
| Akuthota, P | 1 |
| Montone, KT | 1 |
| Szczeklik, W | 2 |
| Mastalerz, L | 1 |
| Sokolowska, B | 1 |
| Sanak, M | 1 |
| Nizankowska-Mogilnicka, E | 1 |
| Dropiński, J | 1 |
| Sokołowska, B | 1 |
| Celińska-Lowenhoff, M | 1 |
| Milewski, M | 1 |
| Szczeklik, A | 1 |
| Kumar, N | 1 |
| Vaish, AK | 1 |
| Scadding, GK | 1 |
| Durham, SR | 1 |
| Mirakian, R | 1 |
| Jones, NS | 1 |
| Drake-Lee, AB | 1 |
| Ryan, D | 1 |
| Dixon, TA | 1 |
| Huber, PA | 1 |
| Nasser, SM | 1 |
| Russi, EW | 1 |
| Suzuki, N | 1 |
| Arai, Y | 1 |
| Miyamoto, Y | 1 |
| Isokane, N | 1 |
| Fukushima, N | 1 |
| Sano, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Montelukast in the Management of Chronic Rhinosinusitis With Nasal Polyps.[NCT05143502] | Phase 1/Phase 2 | 60 participants (Anticipated) | Interventional | 2022-01-01 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for aspirin and Churg-Strauss Syndrome
| Article | Year |
|---|---|
The molecular genetics of inflammatory, autoimmune, and infectious diseases of the sinonasal tract: a review.
Topics: Aspirin; Autoimmune Diseases; Churg-Strauss Syndrome; Granulomatosis with Polyangiitis; Humans; Infe | 2014 |
[Clinical diagnosis of bronchial asthma].
Topics: Aspergillosis, Allergic Bronchopulmonary; Aspirin; Asthma; Churg-Strauss Syndrome; Diagnosis, Differ | 1999 |
7 other studies available for aspirin and Churg-Strauss Syndrome
| Article | Year |
|---|---|
Eosinophilic granulomatosis with polyangiitis presenting as aspirin-exacerbated respiratory disease.
Topics: Aspirin; Asthma, Aspirin-Induced; Churg-Strauss Syndrome; Granulomatosis with Polyangiitis; Humans; | 2023 |
Atypical eosinophilic granulomatosis with polyangiitis with spontaneous aspirin reactivity and immunoglobulin E-mediated anaphylaxis.
Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; C-Reactive Protein; CD | 2021 |
Aspirin tolerance and leukotriene biosynthesis in Churg-Strauss syndrome.
Topics: Adult; Aspirin; Churg-Strauss Syndrome; Drug Tolerance; Eosinophils; Female; Humans; Leukotriene E4; | 2008 |
[Congestive cardiomyopathy and left intraventricular thrombus as a manifestation of Churg-Strauss syndrome].
Topics: Adult; Aspirin; Cardiomyopathy, Dilated; Churg-Strauss Syndrome; Female; Heart Diseases; Heparin, Lo | 2008 |
Hemiplegia due to Churg Strauss syndrome in a young boy.
Topics: Adolescent; Adrenergic beta-2 Receptor Agonists; Albuterol; Anti-Inflammatory Agents; Anti-Inflammat | 2011 |
BSACI guidelines for the management of rhinosinusitis and nasal polyposis.
Topics: Aspirin; Child; Churg-Strauss Syndrome; Female; Humans; Male; Nasal Polyps; Rhinitis; Sinusitis | 2008 |
[Acute myocardial injury and repeated angina pectoris-like attacks in a young patient with Churg-Strauss syndrome].
Topics: Adult; Age Factors; Angina Pectoris; Aspirin; Asthma; Churg-Strauss Syndrome; Eosinophilia; Humans; | 1991 |