Page last updated: 2024-10-23

aspirin and Chronic Pain

aspirin has been researched along with Chronic Pain in 12 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.

Research Excerpts

ExcerptRelevanceReference
"In total, 27 patients with stable cardiovascular, cerebrovascular or peripheral arterial disease and acute or chronic pain were identified and given dipyrone for at least 5 days in combination with low-dose aspirin."9.24Dipyrone (metamizole) markedly interferes with platelet inhibition by aspirin in patients with acute and chronic pain: A case-control study. ( Hohlfeld, T; Kienbaum, P; Pavlaković, G; Romann, L; Schmitz, A; Werdehausen, R, 2017)
"In total, 27 patients with stable cardiovascular, cerebrovascular or peripheral arterial disease and acute or chronic pain were identified and given dipyrone for at least 5 days in combination with low-dose aspirin."5.24Dipyrone (metamizole) markedly interferes with platelet inhibition by aspirin in patients with acute and chronic pain: A case-control study. ( Hohlfeld, T; Kienbaum, P; Pavlaković, G; Romann, L; Schmitz, A; Werdehausen, R, 2017)
"We know from adult randomised controlled trials that some NSAIDs, such as ibuprofen, naproxen, and aspirin, can be effective in certain chronic pain conditions."4.95Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. ( Anderson, B; Cooper, TE; Eccleston, C; Fisher, E; Wilkinson, NM, 2017)
" In 1980 s, the relevance of aspirin for Reye's syndrome became a problem, then acetaminophen came into use for various kinds of cases such as children, pregnant women and the elderly for pain management or alleviation of fever."3.83[Side Effects of Acetaminophen and their Management]. ( Saeki, S, 2016)
"For a woman with chronic pain, adequate use of pain killers during pregnancy is needed."2.53Ongoing Pharmacological Management of Chronic Pain in Pregnancy. ( Källén, B; Reis, M, 2016)
"Among subjects reporting chronic pain the prevalence of OTC analgesic use was almost twice as high as among subjects without chronic pain."1.42Prevalence of use of non-prescription analgesics in the Norwegian HUNT3 population: Impact of gender, age, exercise and prescription of opioids. ( Borchgrevink, PC; Dale, O; Fredheim, OM; Mahic, M; Romundstad, P; Skurtveit, S, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (83.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Dhokia, M1
Elander, J1
Clements, K1
Gilbert, P1
Eccleston, C1
Cooper, TE1
Fisher, E1
Anderson, B1
Wilkinson, NM1
Saeki, S1
Huang, R1
Jiang, L1
Cao, Y1
Liu, H1
Ping, M1
Li, W1
Xu, Y1
Ning, J1
Chen, Y1
Wang, X1
Dale, O1
Borchgrevink, PC1
Fredheim, OM1
Mahic, M1
Romundstad, P1
Skurtveit, S1
Muehlenberg, K1
Metzler, C1
Pech, O1
Källén, B1
Reis, M1
Meesawatsom, P1
Burston, J1
Hathway, G1
Bennett, A1
Chapman, V1
Schmitz, A1
Romann, L1
Kienbaum, P1
Pavlaković, G1
Werdehausen, R1
Hohlfeld, T1
Ferrara, PE1
Ronconi, G1
Viscito, R1
Pascuzzo, R1
Rosulescu, E1
Ljoka, C1
Maggi, L1
Ferriero, G1
Foti, C1
Du, Y1
Ellert, U1
Zhuang, W1
Knopf, H1
BOYLE, RW1
TABET, RC1
WIGHTMAN, BK1

Reviews

3 reviews available for aspirin and Chronic Pain

ArticleYear
Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents.
    The Cochrane database of systematic reviews, 2017, 08-02, Volume: 8

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Arthritis, Rheumatoid; Asp

2017
Comparative Efficacy of Therapeutics for Chronic Cancer Pain: A Bayesian Network Meta-Analysis.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019, 07-10, Volume: 37, Issue:20

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bayes Theorem; Bridged Bicyclo Compou

2019
Ongoing Pharmacological Management of Chronic Pain in Pregnancy.
    Drugs, 2016, Volume: 76, Issue:9

    Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chr

2016

Trials

2 trials available for aspirin and Chronic Pain

ArticleYear
A randomized-controlled pilot trial of an online compassionate mind training intervention to help people with chronic pain avoid analgesic misuse.
    Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2020, Volume: 34, Issue:7

    Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Arthritis, Rheumatoid; Aspirin; Back Pain; Chr

2020
Dipyrone (metamizole) markedly interferes with platelet inhibition by aspirin in patients with acute and chronic pain: A case-control study.
    European journal of anaesthesiology, 2017, Volume: 34, Issue:5

    Topics: Acute Pain; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platele

2017

Other Studies

7 other studies available for aspirin and Chronic Pain

ArticleYear
[Side Effects of Acetaminophen and their Management].
    Masui. The Japanese journal of anesthesiology, 2016, Volume: 65, Issue:7

    Topics: Acetaminophen; Aspirin; Chronic Pain; Cyclooxygenase 1; Fever; Humans; Pain Management; Reye Syndrom

2016
Prevalence of use of non-prescription analgesics in the Norwegian HUNT3 population: Impact of gender, age, exercise and prescription of opioids.
    BMC public health, 2015, May-02, Volume: 15

    Topics: Acetaminophen; Adult; Age Factors; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Aspirin;

2015
[39-year-old man with 15 years lasting pain in both hands].
    Deutsche medizinische Wochenschrift (1946), 2015, Volume: 140, Issue:16

    Topics: Administration, Oral; Adult; Aspirin; Chronic Pain; Diagnosis, Differential; Hand; Hematopoietic Ste

2015
Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive processing in rat pain models.
    Journal of neuroinflammation, 2016, 09-02, Volume: 13, Issue:1

    Topics: Action Potentials; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Chronic Pain; Disease Mo

2016
Efficacy of mesotherapy using drugs versus normal saline solution in chronic spinal pain: a retrospective study.
    International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation, 2017, Volume: 40, Issue:2

    Topics: Analgesics; Anesthetics, Local; Aspirin; Back Pain; Chronic Pain; Female; Follow-Up Studies; Humans;

2017
Analgesic use in a national community sample of German children and adolescents.
    European journal of pain (London, England), 2012, Volume: 16, Issue:6

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics; Aspirin; Child; Child, Preschool; Chronic Pain; F

2012
ANALGESIC EFFECT OF PRODILIDINE HYDROCHLORIDE (5054) IN ELDERLY PATIENTS WITH CHRONIC PAIN SYNDROME.
    Journal of the American Geriatrics Society, 1964, Volume: 12

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Arthritis; Arthritis, Rheumatoid; Aspirin; Chron

1964