aspirin has been researched along with Cholera in 7 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Cholera: An acute diarrheal disease endemic in India and Southeast Asia whose causative agent is VIBRIO CHOLERAE. This condition can lead to severe dehydration in a matter of hours unless quickly treated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized double blind controlled clinical trial was conducted on 30 patients with cholera and 18 patients with severe non-cholera diarrhoea, to study the antisecretory effect of acetylsalicylic acid (aspirin)." | 9.06 | A randomized double blind trial of aspirin versus placebo in cholera and non-cholera diarrhoea. ( Bardhan, PK; Islam, A; Islam, MR; Rahman, M, 1986) |
| "The effect of aspirin on normal and cholera toxin-stimulated electrolyte transport has been investigated in vitro, because this drug appears to inhibit cholera toxin-induced intestinal secretion in in vivo animal models." | 7.65 | Effect of aspirin on normal and cholera toxin-stimulated intestinal electrolyte transport. ( Farris, RK; Morris, SM; Powell, DW; Tapper, EJ, 1976) |
| "A randomized double blind controlled clinical trial was conducted on 30 patients with cholera and 18 patients with severe non-cholera diarrhoea, to study the antisecretory effect of acetylsalicylic acid (aspirin)." | 5.06 | A randomized double blind trial of aspirin versus placebo in cholera and non-cholera diarrhoea. ( Bardhan, PK; Islam, A; Islam, MR; Rahman, M, 1986) |
| "The effect of aspirin on normal and cholera toxin-stimulated electrolyte transport has been investigated in vitro, because this drug appears to inhibit cholera toxin-induced intestinal secretion in in vivo animal models." | 3.65 | Effect of aspirin on normal and cholera toxin-stimulated intestinal electrolyte transport. ( Farris, RK; Morris, SM; Powell, DW; Tapper, EJ, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nalin, DR | 1 |
| Farris, RK | 1 |
| Tapper, EJ | 1 |
| Powell, DW | 1 |
| Morris, SM | 1 |
| Islam, A | 1 |
| Bardhan, PK | 1 |
| Islam, MR | 1 |
| Rahman, M | 1 |
| Kimberg, DV | 1 |
| Field, M | 1 |
| Gershon, E | 1 |
| Henderson, A | 1 |
| Jacoby, HI | 1 |
| Marshall, CH | 1 |
| Finck, AD | 1 |
| Katz, RL | 1 |
| Lexomboon, U | 1 |
| Goth, A | 1 |
| Finkelstein, RA | 1 |
1 trial available for aspirin and Cholera
| Article | Year |
|---|---|
A randomized double blind trial of aspirin versus placebo in cholera and non-cholera diarrhoea.
Topics: Adult; Aspirin; Cholera; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Feces; Female; Hum | 1986 |
6 other studies available for aspirin and Cholera
| Article | Year |
|---|---|
Letter: Failure of aspirin to reverse intestinal secretion after cholera toxin in dogs.
Topics: Animals; Antitoxins; Aspirin; Cholera; Dogs; Enterotoxins; Intestinal Secretions; Sodium Salicylate; | 1976 |
Effect of aspirin on normal and cholera toxin-stimulated intestinal electrolyte transport.
Topics: Animals; Aspirin; Biological Transport; Cholera; Cyclic AMP; Cyclic GMP; Electrolytes; Electrophysio | 1976 |
Effects of prostaglandins and cholera enterotoxin on intestinal mucosal cyclic AMP accumulation. Evidence against an essential role for prostaglandins in the action of toxin.
Topics: Adenylyl Cyclases; Animals; Aspirin; Cholera; Cyclic AMP; Drug Synergism; Enterotoxins; Enzyme Activ | 1974 |
Antagonism of cholera enterotoxin by anti-inflammatory agents in the rat.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Aspirin; Body Fluids; Body Weight; Cholera; | 1972 |
Prevention of cholera-induced intestinal secretion in the cat by aspirin.
Topics: Animals; Aspirin; Cats; Cholera; Diarrhea; Disease Models, Animal; Female; Intestinal Secretions; Ma | 1972 |
Applications of the mouse foot edema test in evaluation of anti-cholera drugs.
Topics: Animals; Anti-Infective Agents; Aspirin; Chloramphenicol; Cholera; Cycloheximide; Dactinomycin; Diur | 1971 |