Page last updated: 2024-10-23

aspirin and Chest Pain

aspirin has been researched along with Chest Pain in 108 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Chest Pain: Pressure, burning, or numbness in the chest.

Research Excerpts

ExcerptRelevanceReference
" This randomized double-blind controlled trial seeks to prove the utility of fentanyl as an alternate first-line analgesic for ischemic-type chest pain in the prehospital setting."9.22Comparison of Fentanyl and Morphine in the Prehospital Treatment of Ischemic Type Chest Pain. ( Ariano, RE; Grierson, RA; Weldon, ER, 2016)
" The risk of clinically significant bleeding with rivaroxaban versus placebo increased in a dose-dependent manner (hazard ratios [HRs] 2."9.14Rivaroxaban versus placebo in patients with acute coronary syndromes (ATLAS ACS-TIMI 46): a randomised, double-blind, phase II trial. ( Barnathan, ES; Bordes, P; Braunwald, E; Burton, P; Gibson, CM; Hricak, V; Markov, V; Mega, JL; Misselwitz, F; Mohanavelu, S; Oppenheimer, L; Poulter, R; Witkowski, A, 2009)
" Data on all 911 calls for chest pain and self-administration of aspirin were collected from the medical incident report form (MIRF)."9.12A community intervention by firefighters to increase 911 calls and aspirin use for chest pain. ( Cagle, A; Diehr, P; Eisenberg, M; Meischke, H; Rowe, S, 2006)
"In this hypothesis generating pilot analysis, dipyrone medication in aspirin treated coronary artery disease patients is associated with an increased cumulative incidence of death, MI or stroke as well as all-cause mortality and ischemic events."7.85Analgesic medication with dipyrone in patients with coronary artery disease: Relation to MACCE. ( Achilles, A; Dannenberg, L; Hohlfeld, T; Kelm, M; Levkau, B; Mohring, A; Piayda, K; Polzin, A; Zeus, T, 2017)
"We aimed to prospectively evaluate the prevalence of biochemical aspirin resistance in patients on aspirin therapy who were admitted to the emergency clinic with chest pain."7.76The clinical significance of aspirin resistance in patients with chest pain. ( Acikel, S; Atar, A; Atar, I; Aydinalp, A; Bozbas, H; Ertan, C; Gulmez, O; Muderrisoglu, H; Ozgul, A; Ozin, B, 2010)
"The study aimed to determine whether aspirin therapy was differentially administered according to race, sex, or age in patients with undifferentiated chest pain who presented to an urban academic emergency department."7.76Aspirin administration in ED patients who presented with undifferentiated chest pain: age, race, and sex effects. ( Hollander, JE; Shofer, FS; Takakuwa, KM, 2010)
"Aspirin's role in the management of suspected myocardial infarction has been well established."7.71A study of the use of aspirin by general practitioners in suspected myocardial infarction. ( O'Shea, EB, 2001)
"Early aspirin administration during an acute myocardial infarction (AMI) decreases morbidity and mortality."7.70Prevalence of aspirin use among patients calling 9-1-1 for chest pain. ( Eisenberg, MS; Jaffy, MB; Meischke, H, 1998)
"We describe a case of eosinophilic esophagitis in a 38-year-old man with aspirin-sensitivity asthma which presented as noncardiac chest pain."7.69Chest pain in an aspirin-sensitive asthmatic patient. Eosinophilic esophagitis causing esophageal dysmotility. ( Elliott, DE; Hempel, SL, 1996)
" This randomized double-blind controlled trial seeks to prove the utility of fentanyl as an alternate first-line analgesic for ischemic-type chest pain in the prehospital setting."5.22Comparison of Fentanyl and Morphine in the Prehospital Treatment of Ischemic Type Chest Pain. ( Ariano, RE; Grierson, RA; Weldon, ER, 2016)
" The risk of clinically significant bleeding with rivaroxaban versus placebo increased in a dose-dependent manner (hazard ratios [HRs] 2."5.14Rivaroxaban versus placebo in patients with acute coronary syndromes (ATLAS ACS-TIMI 46): a randomised, double-blind, phase II trial. ( Barnathan, ES; Bordes, P; Braunwald, E; Burton, P; Gibson, CM; Hricak, V; Markov, V; Mega, JL; Misselwitz, F; Mohanavelu, S; Oppenheimer, L; Poulter, R; Witkowski, A, 2009)
" Data on all 911 calls for chest pain and self-administration of aspirin were collected from the medical incident report form (MIRF)."5.12A community intervention by firefighters to increase 911 calls and aspirin use for chest pain. ( Cagle, A; Diehr, P; Eisenberg, M; Meischke, H; Rowe, S, 2006)
" In patients with NSTEMI/UA, beta-blockers, nitrates and calcium antagonists will improve chest pain, and invasive management of ACS is indicated in < 48 h, if risk factors are present."4.82[Acute chest pain]. ( Perings, C; Trappe, HJ, 2005)
"The American College of Cardiology Foundation/American Heart Association guidelines for acute coronary syndrome (ACS) recommend immediate aspirin (ASA) administration, an electrocardiogram (ECG) in less than 10 minutes, and a door-in to door-out (DIDO) time less than 30 minutes for interfacility transfer."3.85Adult Chest Pain in the Pediatric Emergency Department: Treatment and Timeliness From Door In To Door Out. ( Costello, BE; Flueckiger, PB; Mahle, WT; Sacks, JH; Spandorfer, PR, 2017)
"In this hypothesis generating pilot analysis, dipyrone medication in aspirin treated coronary artery disease patients is associated with an increased cumulative incidence of death, MI or stroke as well as all-cause mortality and ischemic events."3.85Analgesic medication with dipyrone in patients with coronary artery disease: Relation to MACCE. ( Achilles, A; Dannenberg, L; Hohlfeld, T; Kelm, M; Levkau, B; Mohring, A; Piayda, K; Polzin, A; Zeus, T, 2017)
" We present the case of a 50-year-old male with the Samter-Beer triad of asthma, nasal polyps, and salicylate intolerance with an ST elevation myocardial infarction complicated with cardiac arrest due to multi-vessel coronary artery spasm secondary to aspirin anaphylaxis."3.81Kounis syndrome with Samter-Beer triad treated with intracoronary adrenaline. ( Ihdayhid, AR; Rankin, J, 2015)
" His initial ECG and troponin rise supported the diagnosis of myopericarditis for which he was treated with aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) with good response initially."3.79Striking temporally dynamic ECG changes associated with recurrent chest pain in a case of myopericarditis. ( Abdelbar, A; Elmahy, H; Schmitt, M, 2013)
"The American College of Cardiology and the American Heart Association recommend early aspirin administration to patients with symptoms of acute coronary syndrome (ACS)/acute myocardial infarction (AMI)."3.79Aspirin administration by emergency medical dispatchers using a protocol-driven aspirin diagnostic and instruction tool. ( Barron, T; Clawson, J; Gummett, J; Olola, CH; Patterson, B; Robinson, D; Scott, G; Shiner, R; Wrigley, F, 2013)
" In particular, an herbal combination including Tribulus terrestris (TT), Avena sativa (AS), and Panax Ginseng (PG), which may be effective in treatment of atherosclerosis and thrombosis, is used by patients with coronary artery disease."3.78[Three case reports of the use of herbal combinations resulted in stent thrombosis: herbal combinations; friend or foe?]. ( Erdoğan, E; Göktekin, Ö; Tasal, A; Vatankulu, MA, 2012)
"The study aimed to determine whether aspirin therapy was differentially administered according to race, sex, or age in patients with undifferentiated chest pain who presented to an urban academic emergency department."3.76Aspirin administration in ED patients who presented with undifferentiated chest pain: age, race, and sex effects. ( Hollander, JE; Shofer, FS; Takakuwa, KM, 2010)
"We aimed to prospectively evaluate the prevalence of biochemical aspirin resistance in patients on aspirin therapy who were admitted to the emergency clinic with chest pain."3.76The clinical significance of aspirin resistance in patients with chest pain. ( Acikel, S; Atar, A; Atar, I; Aydinalp, A; Bozbas, H; Ertan, C; Gulmez, O; Muderrisoglu, H; Ozgul, A; Ozin, B, 2010)
"The presence of typical chest pain, aspirin use, diabetes, and an age >64 years is associated with an increased probability of coronary artery disease in patients admitted to chest pain units."3.73[A new risk score for patients with a normal or non-diagnostic ECG admitted to a chest pain unit]. ( Andueza, J; Bueno, H; de Miguel, J; Estévez, A; Martínez-Sellés, M; Ortiz, J, 2005)
"Aspirin's role in the management of suspected myocardial infarction has been well established."3.71A study of the use of aspirin by general practitioners in suspected myocardial infarction. ( O'Shea, EB, 2001)
"Early aspirin administration during an acute myocardial infarction (AMI) decreases morbidity and mortality."3.70Prevalence of aspirin use among patients calling 9-1-1 for chest pain. ( Eisenberg, MS; Jaffy, MB; Meischke, H, 1998)
"The present study was designed to investigate whether the prior use of aspirin could influence the severity of the manifestation of acute coronary artery syndromes, given the well-documented observations that aspirin can prevent myocardial infarction, stroke, and death in cardiovascular disease."3.69Previous aspirin use may attenuate the severity of the manifestation of acute ischemic syndromes. ( Garcia-Dorado, D; Oliveras, J; Sambola, A; Santos, M; Soler Soler, J; Théroux, P; Tornos, P, 1995)
"We describe a case of eosinophilic esophagitis in a 38-year-old man with aspirin-sensitivity asthma which presented as noncardiac chest pain."3.69Chest pain in an aspirin-sensitive asthmatic patient. Eosinophilic esophagitis causing esophageal dysmotility. ( Elliott, DE; Hempel, SL, 1996)
"Kawasaki disease is an acute, febrile vasculitis of childhood that affects medium-sized arteries, predominantly the coronary arteries."2.61Pleural effusion as an atypical presentation of Kawasaki disease: a case report and review of the literature. ( Arslanoglu Aydin, E; Aydin, O; Bilginer, Y; Demir, S; Ozen, S, 2019)
"The most common complication is recurrence, occurring in up to 30% of cases after a first episode of pericarditis."2.55Acute and Recurrent Pericarditis. ( Gaita, F; Imazio, M, 2017)
"Myocardial infarction is common among the elderly."2.39Myocardial infarction. Considerations for geriatric patients. ( Sinclair, D, 1994)
"Aspirin was transiently discontinued for 2 days in one patient undergoing percutaneous coronary intervention."1.72Profile and outcomes of patients with mediastinal hematoma after cardiac catheterization: A retrospective analysis. ( Luo, XL; Qiao, SB; Wan, JY; Yang, WX; Yuan, JS; Zhang, J, 2022)
"The score was predictive of recurrence among most patient subgroups."1.62A risk score for pericarditis recurrence. ( Antonopoulos, AS; Imazio, M; Karavidas, A; Lazaros, G; Lazarou, E; Tousoulis, D; Toutouzas, K; Tsioufis, C; Vasileiou, P; Vassilopoulos, D; Vlachopoulos, C, 2021)
"Patients with acute pericarditis have distinct presenting clinical, biochemical and prognostic features according to age and sex."1.62Age- and sex-based differences in patients with acute pericarditis. ( Antonopoulos, AS; Lazaros, G; Lazarou, E; Tousoulis, D; Vassilopoulos, D; Vlachopoulos, C; Vogiatzi, G, 2021)
"Nasal viral PCR was positive for Influenza A."1.48Possible association of influenza A infection and reverse takotsubo syndrome. ( Aoi, S; Golfeyz, S; Harrington, M; Kobayashi, T, 2018)
"Although Kounis syndrome is a rare phenomenon, physicians should be aware of its physiopathological mechanisms in order to treat it appropriately."1.46Management of Kounis syndrome: two case reports. ( Chebili, N; Kraiem, H; Mejri, O; Naija, M; Omri, M, 2017)
"Acute myocardial infarction is rare in pregnancy; however, the emerging trend towards advanced maternal age and the rising prevalence of obesity and diabetes suggest that more cases of myocardial infarction are likely to be encountered in pregnancy."1.39Acute myocardial infarction in pregnancy following unlicensed use of methylenedioxymethamphetamine ('Ecstasy'). ( Dutton, P; Okunoye, GO, 2013)
"Recurrent Takotsubo cardiomyopathy is a relatively uncommon condition seen in patients with severe physical or emotional stress."1.39An unusual cause of recurrent chest pain in an adult woman: a case of recurrent stress-induced (Takotsubo) cardiomyopathy. ( Aryal, MR; Hope, EJ; Mainali, NR; Pradhan, R, 2013)
"Pericarditis is seen quite often in daily clinical practice."1.38[A young man with recurrent chest pain]. ( Boomsma, MF; Dambrink, JH; Steenmeijer, R, 2012)
"Shrinking lung syndrome is characterized by pulmonary compromise secondary to unilateral or bilateral paralysis of the diaphragm."1.37Shrinking lung syndrome in pregnancy complicated by antiphospholipid antibody syndrome. ( Brost, BC; DeStephano, CC; Meena, M; Watson, WJ, 2011)
"Sex disparities in the diagnosis and treatment of chest pain or suspected angina have been demonstrated in multiple clinical settings."1.36Influence of sex on the out-of-hospital management of chest pain. ( Armstrong, K; Facenda, K; Mechem, CC; Meisel, ZF; Peacock, N; Pollack, CV; Shofer, FS, 2010)
"Sickle cell disease is considered protective against large vessel coronary artery disease."1.32Acute myocardial infarction in a young man with sickle cell disease. ( Sherman, SC; Sulé, HP, 2004)

Research

Studies (108)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (17.59)18.2507
2000's24 (22.22)29.6817
2010's54 (50.00)24.3611
2020's11 (10.19)2.80

Authors

AuthorsStudies
Luo, XL1
Yang, WX1
Zhang, J1
Yuan, JS1
Wan, JY1
Qiao, SB1
Kishi, Y1
Aota, Y1
Horie, Y1
Sutoh, A1
Moriyama, M1
Okabe, M1
Iguchi, T1
Yokouchi, Y1
Gotoh, A1
Maetani, I1
Møller, AL1
Rytgaard, HCW1
Mills, EHA1
Christensen, HC1
Blomberg, SNF1
Folke, F1
Kragholm, KH1
Lippert, F1
Gislason, G1
Køber, L1
Gerds, TA1
Torp-Pedersen, C1
Braumann, S1
Faber-Zameitat, C1
Macherey-Meyer, S1
Tichelbäcker, T1
Meertens, M1
Heyne, S1
Nießen, F1
Nies, RJ1
Nettersheim, F1
Reuter, H1
Pfister, R1
Hellmich, M1
Burst, V1
Baldus, S1
Lee, S2
Adler, C1
Nguyen, NN1
Dudouet, P1
Dhiver, C1
Gautret, P1
Arslanoglu Aydin, E1
Demir, S1
Aydin, O1
Bilginer, Y1
Ozen, S1
Kashou, AH1
May, AM1
Noseworthy, PA1
Oluwole, AS1
Virk, HUH1
Witzke, C1
Hertz, JT1
Sakita, FM1
Kweka, GL1
Bloomfield, GS1
Bartlett, JA1
Tarimo, TG1
Temu, G1
Bettger, JP1
Thielman, NM1
Lazaros, G2
Antonopoulos, AS2
Lazarou, E2
Vlachopoulos, C2
Vogiatzi, G1
Vassilopoulos, D2
Tousoulis, D2
Kim, BS1
Chan, N1
Hsu, G1
Makaryus, AN1
Chopra, M1
Cohen, SL1
Makaryus, JN1
Imazio, M2
Vasileiou, P1
Karavidas, A1
Toutouzas, K1
Tsioufis, C1
Sacks, JH1
Flueckiger, PB1
Spandorfer, PR1
Mahle, WT1
Costello, BE1
Omri, M1
Kraiem, H1
Mejri, O1
Naija, M1
Chebili, N1
Bishop, W1
Girao, G1
Blackwood, B1
Liebmann, O1
Binder, W1
Gaita, F1
Frisch, A1
Heidle, KJ1
Frisch, SO1
Ata, A1
Kramer, B1
Colleran, C1
Carlson, JN1
Mohseni, M1
Szymanski, T1
Zoltowska, DM1
Agrawal, Y1
Kalavakunta, JK1
Qureshi, R1
Kao, L1
Gupta, RP1
Taylor, M1
Boudoulas, KD1
Leroux, E1
Houser, C1
Tabas, JA1
Mattu, A1
Brady, W1
Davis, JE1
Youmans, QR1
Unger, ED1
Benzuly, KH1
Slostad, BD1
Anavekar, NS2
Golfeyz, S1
Kobayashi, T1
Aoi, S1
Harrington, M1
Saad Shaukat, MH1
Tatusov, A1
Nappi, A1
Yager, N1
Tafoya, C1
Singh, A1
Gaba, P1
Parikh, SA1
Collins, MB1
Mainali, NR1
Aryal, MR1
Pradhan, R1
Hope, EJ1
Elmahy, H1
Abdelbar, A1
Schmitt, M1
Okunoye, GO1
Dutton, P1
Sato, D1
Koga, S1
Yasunaga, T1
Nakata, T1
Takeno, M1
Koide, Y1
Ikeda, S1
Ashizawa, N1
Maemura, K1
García Martos, E1
García Guerrero, T1
Carro Rossell, J1
Jiménez Jaén, C1
Kennedy, SA1
Singh, SM1
Kupsky, DF1
Tweet, MS1
Wilson, SR1
Kronzon, I1
Machnicki, SC1
Ruiz, CE1
Terzian, Z1
Henry-Feugeas, MC1
Billebeau, G1
Nejjari, M1
Ducrocq, G1
Debray, MP1
Steg, PG1
Ou, P1
Stub, D1
Smith, K1
Bernard, S1
Nehme, Z1
Stephenson, M1
Bray, JE1
Cameron, P1
Barger, B1
Ellims, AH1
Taylor, AJ1
Meredith, IT1
Kaye, DM1
Ihdayhid, AR1
Rankin, J1
Singletary, EM2
Zideman, DA2
De Buck, ED1
Chang, WT1
Jensen, JL2
Swain, JM2
Woodin, JA1
Blanchard, IE1
Herrington, RA1
Pellegrino, JL2
Hood, NA1
Lojero-Wheatley, LF2
Markenson, DS1
Yang, HJ1
Charlton, NP1
Epstein, JL1
Ferguson, JD1
MacPherson, AI1
Smith, WW1
Weldon, ER1
Ariano, RE1
Grierson, RA1
Pursnani, A1
Celeng, C1
Schlett, CL1
Mayrhofer, T1
Zakroysky, P1
Lee, H1
Ferencik, M1
Fleg, JL1
Bamberg, F1
Wiviott, SD2
Truong, QA1
Udelson, JE1
Nagurney, JT1
Hoffmann, U1
Son, R1
Higuchi, T1
Mizuno, A1
Koyamada, R1
Okada, S1
Yamashiro, Y1
Gouda, P1
Bainey, K1
Welsh, R1
Zhao, YT1
Tu, I1
Nilsson, S1
Järemo, P1
Mirra, M1
Kola, N1
Mattiello, G1
Morisco, C1
Spinelli, L1
Achilles, A1
Mohring, A1
Dannenberg, L1
Piayda, K1
Levkau, B1
Hohlfeld, T1
Zeus, T1
Kelm, M1
Polzin, A1
Mrdovic, I1
Perunicic, J1
Asanin, M1
Matic, M1
Vasiljevic, Z1
Ostojic, M1
Cohen, M1
Rocher, F1
Brunschwig, C1
Lebrun, C1
Mega, JL1
Braunwald, E1
Mohanavelu, S1
Burton, P1
Poulter, R1
Misselwitz, F1
Hricak, V1
Barnathan, ES1
Bordes, P1
Witkowski, A1
Markov, V1
Oppenheimer, L1
Gibson, CM1
Zimmer, V1
Lammert, F1
Meisel, ZF1
Armstrong, K1
Mechem, CC1
Shofer, FS2
Peacock, N1
Facenda, K1
Pollack, CV1
Aydinalp, A1
Atar, I1
Gulmez, O1
Atar, A1
Acikel, S1
Bozbas, H1
Ozgul, A1
Ertan, C1
Ozin, B1
Muderrisoglu, H1
Takakuwa, KM1
Hollander, JE1
Soysal, D1
Karakuş, V1
Yavaş, HH1
Biçeroğlu, S1
Köseoğlu, M1
Yeşil, M1
Meena, M1
DeStephano, CC1
Watson, WJ1
Brost, BC1
Rayoo, R1
Sharma, N1
van Gaal, WJ1
Tzeng, SS1
Liou, JT1
Chia, PL1
Lee, E1
Barron, T1
Clawson, J1
Scott, G1
Patterson, B1
Shiner, R1
Robinson, D1
Wrigley, F1
Gummett, J1
Olola, CH1
Steenmeijer, R1
Dambrink, JH1
Boomsma, MF1
Vatankulu, MA1
Tasal, A1
Erdoğan, E1
Göktekin, Ö1
Shaheen, K1
Hader, I1
Alraiyes, AH1
Reed, M1
Alraies, MC1
Bledsoe, BE1
Hoey, J1
Letts, DP1
Constantine, JC1
Littmann, L1
Sherman, SC1
Sulé, HP1
Ohashi, N1
Sumii, K1
Inoue, R1
Nakanishi, T1
Gomyo, Y1
Higashikuni, Y1
Sata, M1
Nagai, R1
Lemaitre, F1
Close, L1
Plein, D1
Silance, PG1
Vandenbossche, JL1
Levine, M1
Wong, D1
Brown, DF1
Nadel, ES1
Martínez-Sellés, M1
Ortiz, J1
Estévez, A1
Andueza, J1
de Miguel, J1
Bueno, H1
Trappe, HJ1
Perings, C1
Meischke, H2
Diehr, P1
Rowe, S1
Cagle, A1
Eisenberg, M1
Casella, G1
Greco, C1
Maggioni, AP1
Di Pasquale, G1
Tuncer, CM1
Iltimur, K1
Tacar, O1
Hatipoglu, SE1
O'Donoghue, M1
Chih, S1
McKeown, B1
Dobarro, D1
Gómez-Rubín, MC1
Sánchez-Recalde, A1
Moreno, R1
Garcia-Dorado, D1
Théroux, P1
Tornos, P1
Sambola, A1
Oliveras, J1
Santos, M1
Soler Soler, J1
Hargreaves, MR1
Firoozan, S1
Forfar, JC1
Gregor, RD1
Bata, IR1
Eastwood, BJ1
Garner, JB1
Guernsey, JR1
MacKenzie, BR1
Rautaharju, PM1
Wolf, HK1
Iruela, LM1
Sinclair, D1
De Caterina, R1
Lanza, M1
Manca, G1
Strata, GB1
Maffei, S1
Salvatore, L1
Short, AD1
West, B1
Casaccia, M1
Bertello, F1
De Bernardi, A1
Sicuro, M1
Scacciatella, P1
Ng, WL1
Sim, EK1
Yeo, TC1
Lim, YT1
Hempel, SL1
Elliott, DE1
Julian, DG1
Herlitz, J1
Haglid, M1
Hartford, M1
Karlson, BW1
Karlsson, T1
Lindelöw, B1
Caidahl, K1
Jaffy, MB1
Eisenberg, MS1
Chiamvimonvat, V1
Sternberg, L1
Robbins, MA1
Marso, SP1
Wolski, K1
Peterson, J1
Lincoff, AM1
Brener, S1
Bochkareva, EV1
Kucheriavaia, NG1
Kokurina, EV1
Metelitsa, VI1
Kondrat'ev, VV1
Ritzmann, P1
Frey, R1
Rüttimann, S1
Kight, L1
O'Shea, EB1
Robinson, N1
Golledge, P1
Timmis, A1
Braden, GA1
Knapp, HR1
FitzGerald, GA1
Elwood, PC1
Kristensen, SD1
Bath, PM1
Martin, JF1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised Controlled Trial of Oxygen Therapy in Acute Myocardial Infarction (AVOID - Air Verses Oxygen In myocarDial Infarction Study)[NCT01272713]638 participants (Actual)Interventional2011-10-31Active, not recruiting
Strategy to Avoid Excessive Oxygen in Major Burn Patients (SAVE-O2)[NCT04534972]Phase 32,000 participants (Anticipated)Interventional2021-04-15Active, not recruiting
Strategy to Avoid Excessive Oxygen for Critically Ill Trauma Patients (SAVE-O2)[NCT04534959]Phase 36,000 participants (Anticipated)Interventional2020-10-15Active, not recruiting
DETermination of the Role of OXygen in Suspected Acute Myocardial Infarction (DETO2X-AMI) Based on the SWEDEHEART Registry[NCT01787110]Phase 36,629 participants (Actual)Interventional2013-04-30Completed
Rule Out Myocardial Ischemia/Infarction by Computer Assisted Tomography[NCT01084239]Phase 31,000 participants (Actual)Interventional2010-04-30Completed
Non-steroidal Anti-inflammatory Drugs Impair the Platelet Inhibiting Effect of Acetylsalicylic Acid in Coronary Artery Disease Patients[NCT01402804]85 participants (Actual)Observational2011-07-31Completed
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Dose-Escalation and Dose-Confirmation Study to Evaluate the Safety and Efficacy of Rivaroxaban in Combination With Aspirin Alone or With Aspirin and a Thienopyridine in Subjects With Acute Coron[NCT00402597]Phase 23,490 participants (Actual)Interventional2006-11-30Completed
Clopidogrel Hyper-Responsiveness: Incidence and Associated Outcomes in Patients With Cerebral Aneurysms[NCT05945563]208 participants (Anticipated)Observational [Patient Registry]2023-01-17Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Cost-effectiveness

Total cost during index hospitalization (NCT01084239)
Timeframe: Duration of stay in the hospital during the initial visit

InterventionUS Dollars (Mean)
Cardiac CT4026
Standard of Care3874

Healthcare Utilization

Number of patients with diagnostic testing (CCTA, ETT, SPECT, stress echocardiography, and invasive coronary angiography) (NCT01084239)
Timeframe: Duration of stay in the hospital during the initial visit

Interventionparticipants (Number)
Cardiac CT492
Standard of Care390

Length of Hospital Stay

(NCT01084239)
Timeframe: Duration of stay in the hospital during the initial visit

Interventionhours (Mean)
Cardiac CT23.2
Standard of Care30.8

MACE

Major Adverse Cardiovascular Events, All though these events are called MACE they do not qualify as adverse or serious adverse events. As these events are expected in some individuals in this population. Only MACE that occured within 72 hours after hospital discharge were considered serious adverse events in this trial. There were no such events. (NCT01084239)
Timeframe: 72 hours after discharge up to 28 days after enrollment.

Interventionevents (Number)
Cardiac CT6
Standard of Care2

Rate of ED Discharge

Direct discharge from Emergency Department (NCT01084239)
Timeframe: Duration of stay in the hospital during the initial visit

Interventionparticipants (Number)
Cardiac CT233
Standard of Care62

Time to Diagnosis

(NCT01084239)
Timeframe: Time from ED arrival to first positive test (all tests except Echocardiography Rest and including troponins ) if discharge diagnosis is ACS, otherwise time to performance of last test (all tests except Echocardiography Rest and including troponins ).

Interventionhours (Mean)
Cardiac CT10.4
Standard of Care18.7

The Composite Endpoint of All Cause Death, Myocardial Infarction (MI) (Including Repeat MI), Stroke (Ischemic, Hemorrhagic or Unknown), or Severe Recurrent Ischemia Requiring Revascularization (Primary Efficacy)

The number of patients who died due to any cause or had a first occurrence of MI (including repeat MI) or stroke (ischemic, hemorrhagic or unknown) or severe recurrent ischemia requiring revascularization from the time of randomization to the last date of patient contact. (NCT00402597)
Timeframe: Day 1 to Day 210

InterventionPatients (Number)
Placebo83
Riva 5 mg Total Daily Dose (TDD)23
Riva 10 mg TDD55
Riva 15 mg TDD27
Riva 20 mg TDD36

The Composite Endpoint of Cardiovascular Death, Myocardial Infarction (MI), or Stroke

The number of patients with the composite endpoint of cardiovascular death or MI or stroke that occurred from the time of randomization to the last date of patient contact. (NCT00402597)
Timeframe: Day 1 to Day 210

InterventionPatients (Number)
Placebo63
Riva 5 mg Total Daily Dose (TDD)18
Riva 10 mg TDD40
Riva 15 mg TDD21
Riva 20 mg TDD21

The Composite Endpoint of Death (All Cause), MI (or reMI), Stroke, Severe Recurrent Ischemia Requiring Revascularization, or Thrombolysis in Myocardial Infarction (TIMI) (Major or Minor Bleeding) to Assess the Net Clinical Benefit

The number of patients who died due to any cause or had a first occurrence of MI (or repeat MI), or stroke, or severe recurrent ischemia requiring revascularization, or TIMI (major or minor bleeding) from the time of randomization to the last date of patient contact to assess the net clinical benefit of rivaroxaban. (NCT00402597)
Timeframe: Day 1 to Day 210

InterventionPatients (Number)
Placebo88
Riva 5 mg Total Daily Dose (TDD)24
Riva 10 mg TDD71
Riva 15 mg TDD35
Riva 20 mg TDD48

The Composite Endpoint of Death (All Cause), Myocardial Infarction (MI) (or Repeat MI), or Stroke

The number of patients who died due to any cause or had a first occurrence of MI (or repeat MI) or stroke from the time of randomization to the last date of patient contact. (NCT00402597)
Timeframe: Day 1 to Day 210

InterventionPatients (Number)
Placebo66
Riva 5 mg Total Daily Dose (TDD)18
Riva 10 mg TDD40
Riva 15 mg TDD21
Riva 20 mg TDD22

The Number of Deaths (All Cause)

The number of patients who died due to any cause from the time of randomization to the last date of patient contact. (NCT00402597)
Timeframe: Day 1 to Day 210

InterventionPatients (Number)
Placebo18
Riva 5 mg Total Daily Dose (TDD)11
Riva 10 mg TDD9
Riva 15 mg TDD4
Riva 20 mg TDD9

Thrombolysis in Myocardial Infarction (TIMI) Clinically Significant Bleeding Events (Primary Safety)

The number of patients with a first occurrence of a TIMI clinically significant bleeding event that occurred from the time of randomization to the time of the last patient contact. TIMI clinically significant bleeding events included TIMI minor bleeding events, TIMI major bleeding events, or any bleeding that required medical attention. (NCT00402597)
Timeframe: Day 1 to Day 210

InterventionPatients (Number)
Placebo36
Riva 5 mg Total Daily Dose (TDD)17
Riva 10 mg TDD109
Riva 15 mg TDD43
Riva 20 mg TDD89

Reviews

11 reviews available for aspirin and Chest Pain

ArticleYear
Pericarditis related to post-acute COVID infection: A case report and review of the literature.
    Acta microbiologica et immunologica Hungarica, 2023, Jun-16, Volume: 70, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chest Pain; Colchicine; COVID-19; Female; Humans;

2023
Pleural effusion as an atypical presentation of Kawasaki disease: a case report and review of the literature.
    Journal of medical case reports, 2019, Nov-25, Volume: 13, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chest Pain; Chest Tubes; Dr

2019
Acute and Recurrent Pericarditis.
    Cardiology clinics, 2017, Volume: 35, Issue:4

    Topics: Acute Disease; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chest Pain

2017
Cardiac Memory: A Case Report and Review of the Literature.
    The Journal of emergency medicine, 2019, Volume: 57, Issue:1

    Topics: Aged; Amlodipine; Arrhythmias, Cardiac; Aspirin; Bundle-Branch Block; Chest Pain; Electrocardiograph

2019
Part 9: First Aid: 2015 International Consensus on First Aid Science With Treatment Recommendations.
    Circulation, 2015, Oct-20, Volume: 132, Issue:16 Suppl 1

    Topics: Airway Management; Aspirin; Asthma; Cardiopulmonary Resuscitation; Chest Pain; Emergencies; Emergenc

2015
Part 15: First Aid: 2015 American Heart Association and American Red Cross Guidelines Update for First Aid.
    Circulation, 2015, Nov-03, Volume: 132, Issue:18 Suppl 2

    Topics: Anaphylaxis; Aspirin; Burns; Chest Pain; Dehydration; Emergency Medical Services; Epinephrine; First

2015
[Acute myocarditis: from chest pain to cardiogenic shock].
    Annales de cardiologie et d'angeiologie, 2005, Volume: 54, Issue:2

    Topics: Acute Disease; Adult; Aged; Aspirin; Biopsy; Cardiotonic Agents; Chest Pain; Clinical Enzyme Tests;

2005
[Acute chest pain].
    Medizinische Klinik (Munich, Germany : 1983), 2005, Aug-15, Volume: 100, Issue:8

    Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Algorithms; Angina, Unstable; Angioplasty, Balloon

2005
[Secondary prevention of acute coronary syndromes: are we following correctly the guidelines?].
    Giornale italiano di cardiologia (2006), 2006, Volume: 7, Issue:3

    Topics: Acute Disease; Adrenergic beta-Antagonists; Algorithms; Angina, Unstable; Angiotensin-Converting Enz

2006
Myocardial infarction. Considerations for geriatric patients.
    Canadian family physician Medecin de famille canadien, 1994, Volume: 40

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; A

1994
Coronary artery disease in women.
    Canadian family physician Medecin de famille canadien, 1998, Volume: 44

    Topics: Adult; Age Factors; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Angiotensin-Converting En

1998

Trials

8 trials available for aspirin and Chest Pain

ArticleYear
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction.
    Circulation, 2015, Jun-16, Volume: 131, Issue:24

    Topics: Aged; Air; Ambulances; Aspirin; Biomarkers; Chest Pain; Combined Modality Therapy; Coronary Circulat

2015
Comparison of Fentanyl and Morphine in the Prehospital Treatment of Ischemic Type Chest Pain.
    Prehospital emergency care, 2016, Volume: 20, Issue:1

    Topics: Aged; Analgesia; Analgesics, Opioid; Aspirin; Chest Pain; Double-Blind Method; Emergency Medical Ser

2016
Use of Coronary Computed Tomographic Angiography Findings to Modify Statin and Aspirin Prescription in Patients With Acute Chest Pain.
    The American journal of cardiology, 2016, Feb-01, Volume: 117, Issue:3

    Topics: Acute Coronary Syndrome; Adult; Aged; Aspirin; Chest Pain; Coronary Angiography; Decision Making; Di

2016
Rivaroxaban versus placebo in patients with acute coronary syndromes (ATLAS ACS-TIMI 46): a randomised, double-blind, phase II trial.
    Lancet (London, England), 2009, Jul-04, Volume: 374, Issue:9683

    Topics: Acute Coronary Syndrome; Administration, Oral; Aspirin; Chest Pain; Dose-Response Relationship, Drug

2009
A community intervention by firefighters to increase 911 calls and aspirin use for chest pain.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2006, Volume: 13, Issue:4

    Topics: Aged; Aspirin; Chest Pain; Emergency Medical Service Communication Systems; Emergency Medical Servic

2006
Bleeding time and bleeding: an analysis of the relationship of the bleeding time test with parameters of surgical bleeding.
    Blood, 1994, Nov-15, Volume: 84, Issue:10

    Topics: Aspirin; Bleeding Time; Blood Loss, Surgical; Blood Transfusion; Chest Pain; Cohort Studies; Coronar

1994
Chest pain--a strong predictor of adverse cardiac events following precutaneous intervention (from the Evaluation of Platelet IIb/IIIa Inhibitor for Stenting Trial [EPISENT])].
    The American journal of cardiology, 1999, Dec-01, Volume: 84, Issue:11

    Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Chest Pain; Corona

1999
[Acetylsalicylic acid effects on pain sensitivity to myocardial ischemia and skin sensitivity in patients with angina pectoris].
    Terapevticheskii arkhiv, 2000, Volume: 72, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Aspirin; Chest Pain; Double-Blind Method; Electric Stimulation; Electr

2000

Other Studies

89 other studies available for aspirin and Chest Pain

ArticleYear
Profile and outcomes of patients with mediastinal hematoma after cardiac catheterization: A retrospective analysis.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2022, Volume: 99 Suppl 1

    Topics: Aspirin; Cardiac Catheterization; Chest Pain; Hematoma; Humans; Mediastinal Diseases; Retrospective

2022
[Idiopathic esophageal submucosal hematoma during antithrombotic therapy for essential thrombocythemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2022, Volume: 63, Issue:4

    Topics: Aged; Aspirin; Chest Pain; Esophageal Diseases; Female; Fibrinolytic Agents; Gastrointestinal Hemorr

2022
Hypothetical interventions on emergency ambulance and prehospital acetylsalicylic acid administration in myocardial infarction patients presenting without chest pain.
    BMC cardiovascular disorders, 2022, 12-22, Volume: 22, Issue:1

    Topics: Ambulances; Aspirin; Chest Pain; Heart Failure; Humans; Myocardial Infarction

2022
Acute Chest Pain—Diagnostic Accuracy and Pre-Hospital Use of Anticoagulants and Platelet Aggregation Inhibitors
    Deutsches Arzteblatt international, 2023, 05-05, Volume: 120, Issue:18

    Topics: Anticoagulants; Aspirin; Chest Pain; Heparin; Humans; Retrospective Studies

2023
85-Year-Old Man With Chest Pain.
    Mayo Clinic proceedings, 2020, Volume: 95, Issue:1

    Topics: Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Chest Pain; Colchicine; Diagnosis, Differentia

2020
Intense exercise may not be so benign: chest pain in a young athletic woman may be spontaneous coronary artery dissection (SCAD).
    BMJ case reports, 2020, Apr-06, Volume: 13, Issue:4

    Topics: Adult; Aspirin; Chest Pain; Clopidogrel; Coronary Angiography; Coronary Vessel Anomalies; Coronary V

2020
Effect of a Triage-Based Screening Protocol on Diagnosis and Treatment of Acute Coronary Syndrome in a Tanzanian Emergency Department: A Prospective Pre-Post Study.
    Journal of the American Heart Association, 2020, 08-18, Volume: 9, Issue:16

    Topics: Acute Coronary Syndrome; Aspirin; Body Mass Index; Chest Pain; Dyspnea; Electrocardiography; Emergen

2020
Age- and sex-based differences in patients with acute pericarditis.
    European journal of clinical investigation, 2021, Volume: 51, Issue:3

    Topics: Acute Disease; Adult; Age Distribution; Age Factors; Aged; Anti-Inflammatory Agents; Anti-Inflammato

2021
Sex Differences in Coronary Arterial Calcification in Symptomatic Patients.
    The American journal of cardiology, 2021, 06-15, Volume: 149

    Topics: Adult; Aspirin; Chest Pain; Cohort Studies; Computed Tomography Angiography; Coronary Angiography; C

2021
A risk score for pericarditis recurrence.
    European journal of clinical investigation, 2021, Volume: 51, Issue:11

    Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chest Pain; Colchicine;

2021
Adult Chest Pain in the Pediatric Emergency Department: Treatment and Timeliness From Door In To Door Out.
    Pediatric emergency care, 2017, Volume: 33, Issue:11

    Topics: Acute Coronary Syndrome; Adult; Aspirin; Chest Pain; Electrocardiography; Emergency Service, Hospita

2017
Management of Kounis syndrome: two case reports.
    Journal of medical case reports, 2017, May-23, Volume: 11, Issue:1

    Topics: Amoxicillin; Anaphylaxis; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Chest Pain; Clopidogrel

2017
Pragmatic approach to chest pain patients discharged with undetectable high-sensitivity troponin T and normal electrocardiogram: the STABS + CT protocol.
    Internal medicine journal, 2017, Volume: 47, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Angina, Unstable; Aspirin; Biomarkers; Chest Pain; Computed Tomog

2017
A soccer mom with chest pain: Spontaneous coronary artery dissection in a young woman.
    Rhode Island medical journal (2013), 2017, 08-01, Volume: 100, Issue:8

    Topics: Aspirin; Cardiac Catheterization; Chest Pain; Coronary Angiography; Coronary Vessel Anomalies; Diagn

2017
Factors associated with advanced cardiac care in prehospital chest pain patients.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:7

    Topics: Age Distribution; Aged; Aspirin; Cardiac Catheterization; Chest Pain; Coronary Artery Bypass; Corona

2018
Acute pericarditis following endoscopy.
    BMJ case reports, 2018, Feb-05, Volume: 2018

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chest Pain; Conservative Treatment; Electroc

2018
Can aldosterone break your heart? Takotsubo cardiomyopathy in a patient with newly diagnosed primary aldosteronism.
    BMJ case reports, 2018, Feb-05, Volume: 2018

    Topics: Aldosterone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agen

2018
Coronary artery fistula with associated Takotsubo cardiomyopathy: a case report.
    Journal of medical case reports, 2018, Mar-30, Volume: 12, Issue:1

    Topics: Angina Pectoris; Anti-Arrhythmia Agents; Aspirin; Cardiac Catheterization; Catecholamines; Chest Pai

2018
24-year-old with history of smoking tobacco and cannabis · dyspnea · chest tightness.
    The Journal of family practice, 2018, Volume: 67, Issue:9

    Topics: Adult; Antihypertensive Agents; Aspirin; Chest Pain; Coronary Vasospasm; Dyspnea; Humans; Lisinopril

2018
Elderly Man With Chest Pressure.
    Annals of emergency medicine, 2018, Volume: 72, Issue:5

    Topics: Aged; Aspirin; Chest Pain; Dizziness; Electrocardiography; Emergency Service, Hospital; Humans; Male

2018
A Young Woman With Chest Pain.
    JAMA, 2018, Dec-18, Volume: 320, Issue:23

    Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Aortic Dissection; Aspirin; Chest Pain; Clopidogrel;

2018
57-Year-Old Man With Atypical Chest Pain.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:12

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Imaging Techniques; Chest P

2018
Possible association of influenza A infection and reverse takotsubo syndrome.
    BMJ case reports, 2018, Dec-14, Volume: 11, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Antiviral Agents; Aspirin; Atorvastatin; Chest Pain; Coronary Angiogr

2018
Transient sinus arrest due to sinus node artery thrombus after revascularisation of the left circumflex artery.
    BMJ case reports, 2019, Feb-22, Volume: 12, Issue:2

    Topics: Aspirin; Chest Pain; Coronary Angiography; Coronary Sinus; Coronary Thrombosis; Defibrillators, Impl

2019
A Woman With Multiparity Experiencing Chest Pain in Her Early 60s.
    JAMA cardiology, 2019, 07-01, Volume: 4, Issue:7

    Topics: Adrenergic beta-Antagonists; Aspirin; Chest Pain; Clopidogrel; Coronary Vessel Anomalies; Drug Thera

2019
An unusual cause of recurrent chest pain in an adult woman: a case of recurrent stress-induced (Takotsubo) cardiomyopathy.
    BMJ case reports, 2013, May-24, Volume: 2013

    Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Chest Pain; D

2013
Striking temporally dynamic ECG changes associated with recurrent chest pain in a case of myopericarditis.
    BMJ case reports, 2013, May-24, Volume: 2013

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chest Pain; Diagnosis, Differential; Electr

2013
Acute myocardial infarction in pregnancy following unlicensed use of methylenedioxymethamphetamine ('Ecstasy').
    Scottish medical journal, 2013, Volume: 58, Issue:3

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic Uptake Inhibitors; Adult; Aspirin; Bisoprolol; Ch

2013
Culprit segments identified by optical coherence tomography in patients with acute myocardial infarction: two case reports.
    Cardiovascular intervention and therapeutics, 2012, Volume: 27, Issue:1

    Topics: Aged; Anticoagulants; Aspirin; Cardiac Catheterization; Chest Pain; Coronary Angiography; Coronary A

2012
[Hematemesis in an 80-year-old patient with chest pain and nausea].
    Gastroenterologia y hepatologia, 2015, Volume: 38, Issue:1

    Topics: Aged, 80 and over; Aspirin; Chest Pain; Clopidogrel; Esophageal Diseases; Esophagoscopy; Female; Hem

2015
A 28-year-old man with acute chest pain.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2014, Oct-21, Volume: 186, Issue:15

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Chest Pain; Colchicine; Diagnos

2014
30-year-old man with chest pain and nausea.
    Mayo Clinic proceedings, 2014, Volume: 89, Issue:11

    Topics: Acute Coronary Syndrome; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Ba

2014
A constrained heart: a case of sudden onset unrelenting chest pain.
    Circulation, 2014, Oct-28, Volume: 130, Issue:18

    Topics: Analgesics, Opioid; Aspirin; Chest Pain; Clopidogrel; Coronary Angiography; Drug Therapy, Combinatio

2014
Spectral contrast-enhanced cardiac computed tomography for diagnosis of acute myocarditis.
    The Canadian journal of cardiology, 2015, Volume: 31, Issue:5

    Topics: Acute Disease; Aspirin; Chest Pain; Contrast Media; Echocardiography; Electrocardiography; Follow-Up

2015
Kounis syndrome with Samter-Beer triad treated with intracoronary adrenaline.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2015, Nov-15, Volume: 86, Issue:6

    Topics: Anaphylaxis; Aspirin; Asthma; Chest Pain; Coronary Stenosis; Coronary Vessels; Electrocardiography;

2015
A Newly Characterized Hemoglobin Variant with a High Oxygen Affinity, Hb Fuchu-II, Presenting with Acute Myocardial Infarction.
    Internal medicine (Tokyo, Japan), 2016, Volume: 55, Issue:3

    Topics: Aged; Anticoagulants; Aspirin; Chest Pain; Coronary Angiography; Hemoglobins, Abnormal; Humans; Male

2016
The Demise of Morphine Oxygen Nitroglycerin Aspirin (MONA).
    The Canadian journal of cardiology, 2016, Volume: 32, Issue:12

    Topics: Acute Coronary Syndrome; Aspirin; Chest Pain; Evidence-Based Emergency Medicine; Humans; Morphine; N

2016
Acute pulmonary embolism with precordial T-wave inversion and negative D-dimer.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:3

    Topics: Aged; Angiography; Anticoagulants; Aspirin; Chest Pain; Diagnosis, Differential; Dyspnea; Electrocar

2017
Non-coronary chest pain does not affect long-term mortality: a prospective, observational study using a matched population control.
    BMC family practice, 2016, 11-16, Volume: 17, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aspirin; Case-Control Studies; Cause of Death; Chest Pain;

2016
Spontaneous coronary artery dissection in a young woman with polycystic ovarian syndrome.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:6

    Topics: Acute Coronary Syndrome; Adenosine; Adult; Aspirin; Chest Pain; Coronary Angiography; Coronary Vesse

2017
Analgesic medication with dipyrone in patients with coronary artery disease: Relation to MACCE.
    International journal of cardiology, 2017, Jun-01, Volume: 236

    Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Aspirin; Chest Pain; Coronary Artery Disease; Dip

2017
Transient left ventricular apical ballooning complicated by a mural thrombus and outflow tract obstruction in a patient with pheochromocytoma.
    Texas Heart Institute journal, 2008, Volume: 35, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Angina Pectoris; Anticoagulants; Aspirin; Che

2008
Recurrent pericarditis due to natalizumab treatment.
    Neurology, 2009, May-05, Volume: 72, Issue:18

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aspirin; Chest Pain; Colchicine; D

2009
Clinical images: Multiple esophageal submucosal hematomas.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2010, Jan-12, Volume: 182, Issue:1

    Topics: Aged; Anticoagulants; Aspirin; Chest Pain; Esophageal Diseases; Esophagoscopy; Female; Hematemesis;

2010
Influence of sex on the out-of-hospital management of chest pain.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2010, Volume: 17, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Angina Pectoris; Aspirin; Chest Pain; Emergency Medical Services; Fem

2010
The clinical significance of aspirin resistance in patients with chest pain.
    Clinical cardiology, 2010, Volume: 33, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Analysis of Variance; Aspirin; Biomarkers, Pharmacological; Blood Pla

2010
Aspirin administration in ED patients who presented with undifferentiated chest pain: age, race, and sex effects.
    The American journal of emergency medicine, 2010, Volume: 28, Issue:3

    Topics: Acute Coronary Syndrome; Adult; Age Factors; Aspirin; Biomarkers; Chest Pain; Emergency Service, Hos

2010
Understanding angina. When chest pain strikes, it's essential to know what action to take.
    The Johns Hopkins medical letter health after 50, 2010, Volume: 22, Issue:2

    Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Chest Pain; Combined Modality Therapy; Cor

2010
Surviving a heart attack: know the signs and save a life.
    Consumer reports, 2010, Volume: 75, Issue:10

    Topics: Aspirin; Chest Pain; Coronary Angiography; Dizziness; Dyspnea; Echocardiography; Electrocardiography

2010
C-reactive protein in unstable angina pectoris and its relation to coronary angiographic severity and diffusion scores of coronary lesions.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2010, Volume: 10, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris, Variant; Aspirin; Biomarkers; C-Reactive Protein

2010
Shrinking lung syndrome in pregnancy complicated by antiphospholipid antibody syndrome.
    Obstetrics and gynecology, 2011, Volume: 117, Issue:2 Pt 2

    Topics: Adult; Antiphospholipid Syndrome; Aspirin; Cesarean Section; Chest Pain; Dyspnea; Female; Heparin; H

2011
A case of acute stent thrombosis during treatment with the thrombopoietin receptor agonist peptide--romiplostim.
    Heart, lung & circulation, 2012, Volume: 21, Issue:3

    Topics: Acute Disease; Aspirin; Chest Pain; Clopidogrel; Eptifibatide; Female; Humans; Middle Aged; Peptides

2012
Bead-like coronary spasm.
    Internal medicine journal, 2012, Volume: 42, Issue:3

    Topics: Aspirin; Bradycardia; Calcium Channel Blockers; Chest Pain; Coronary Angiography; Coronary Stenosis;

2012
Reverse Takotsubo pattern stress cardiomyopathy in a male patient induced during dobutamine stress echocardiography.
    Annals of the Academy of Medicine, Singapore, 2012, Volume: 41, Issue:6

    Topics: Aspirin; Bisoprolol; Cardiomyopathies; Cardiotonic Agents; Chest Pain; Dobutamine; Echocardiography,

2012
Aspirin administration by emergency medical dispatchers using a protocol-driven aspirin diagnostic and instruction tool.
    Emergency medicine journal : EMJ, 2013, Volume: 30, Issue:7

    Topics: Acute Coronary Syndrome; Aspirin; Chest Pain; Emergency Medical Service Communication Systems; Emerg

2013
[A young man with recurrent chest pain].
    Nederlands tijdschrift voor geneeskunde, 2012, Volume: 156, Issue:31

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chest Pain; Colchicine; Diagnosis, Differential; H

2012
[Three case reports of the use of herbal combinations resulted in stent thrombosis: herbal combinations; friend or foe?].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2012, Volume: 40, Issue:3

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Aspirin; Avena; Chest Pain; Clopidogrel; Co

2012
Left main coronary artery aneurysm.
    QJM : monthly journal of the Association of Physicians, 2014, Volume: 107, Issue:2

    Topics: Aspirin; Chest Pain; Coronary Aneurysm; Female; Humans; Middle Aged; Platelet Aggregation Inhibitors

2014
How to keep chest pain from cramping your style. If you are one of the millions of Americans for whom chest pain is part of daily life, here are some ABCs for getting it under control.
    Harvard heart letter : from Harvard Medical School, 2002, Volume: 13, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Aspirin; Chest Pain; Diet; Exercise; Fema

2002
Is aspirin part of your chest pain protocol?
    Emergency medical services, 2003, Volume: 32, Issue:2

    Topics: Aspirin; Chest Pain; Emergency Medical Services; Fibrinolytic Agents; Humans; Thrombolytic Therapy;

2003
Cocaine-associated chest pain in the emergency department.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2003, Apr-15, Volume: 168, Issue:8

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzodiazepines; Chest Pain; Co

2003
Intermittent noninfarction Q waves: a finding suggestive of latent preexcitation.
    Mayo Clinic proceedings, 2003, Volume: 78, Issue:7

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catheter Ablation; Chest Pain; Diagnosis, D

2003
Acute myocardial infarction in a young man with sickle cell disease.
    The Journal of emergency medicine, 2004, Volume: 27, Issue:1

    Topics: Adult; Anemia, Sickle Cell; Aspirin; Chest Pain; Diagnosis, Differential; Electrocardiography; Emerg

2004
[A 78-year-old man with anterior chest pain].
    Journal of cardiology, 2004, Volume: 43, Issue:6

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Aspirin; Biomarkers; Cardiomyopathie

2004
Reversible left ventricular hypertrophy after tako-tsubo-like cardiomyopathy.
    Acta cardiologica, 2005, Volume: 60, Issue:1

    Topics: Aged; Aspirin; Benzimidazoles; Biphenyl Compounds; Cardiomyopathy, Dilated; Chest Pain; Drug Therapy

2005
Chest pain and arthritis.
    The Journal of emergency medicine, 2005, Volume: 29, Issue:1

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspir

2005
[A new risk score for patients with a normal or non-diagnostic ECG admitted to a chest pain unit].
    Revista espanola de cardiologia, 2005, Volume: 58, Issue:7

    Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chest Pain; Coronary Disease; D

2005
Single coronary artery with retroaortic course. An unusual origin of right Valsalva sinus.
    Saudi medical journal, 2006, Volume: 27, Issue:7

    Topics: Adult; Aspirin; Atorvastatin; Chest Pain; Coronary Vessel Anomalies; Female; Heptanoic Acids; Humans

2006
Clopidogrel response variability and future therapies: clopidogrel: does one size fit all?
    Circulation, 2006, Nov-28, Volume: 114, Issue:22

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Chest Pain; Clopidogrel; Coronary Angiography; Electr

2006
Takotsubo cardiomyopathy.
    Internal medicine journal, 2007, Volume: 37, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiomyopathi

2007
[Severe vasoespasm during coronary angiograms in a patient with Prinzmetal syndrome].
    Medicina clinica, 2008, Mar-08, Volume: 130, Issue:8

    Topics: Administration, Cutaneous; Administration, Oral; Angina Pectoris, Variant; Aspirin; Cardiovascular A

2008
Previous aspirin use may attenuate the severity of the manifestation of acute ischemic syndromes.
    Circulation, 1995, Oct-01, Volume: 92, Issue:7

    Topics: Angina, Unstable; Aspirin; Case-Control Studies; Chest Pain; Electrocardiography; Female; Humans; Ma

1995
Prescription of regular aspirin in patients with chest pain referred to a cardiology outpatient clinic.
    BMJ (Clinical research ed.), 1995, Mar-25, Volume: 310, Issue:6982

    Topics: Angina Pectoris; Aspirin; Cardiology Service, Hospital; Chest Pain; Drug Utilization; Family Practic

1995
Gender differences in the presentation, treatment, and short-term mortality of acute chest pain.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1994, Volume: 17, Issue:6

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Aspirin; Chest Pain; Coronary Angiography

1994
Sudden chest pain with sertraline.
    Lancet (London, England), 1994, Apr-30, Volume: 343, Issue:8905

    Topics: 1-Naphthylamine; Antidepressive Agents; Aspirin; Chest Pain; Coronary Disease; Depression; Humans; M

1994
Early management of myocardial infarction. The challenge for the GPs is to change.
    BMJ (Clinical research ed.), 1994, Apr-30, Volume: 308, Issue:6937

    Topics: Aspirin; Chest Pain; Family Practice; Humans; Myocardial Infarction

1994
[Prehospital management of acute myocardial infarct in an experimental metropolitan system of medical emergencies].
    Giornale italiano di cardiologia, 1996, Volume: 26, Issue:6

    Topics: Adult; Age Distribution; Aged; Aspirin; Chest Pain; Electrocardiography; Emergency Medical Services;

1996
Surgery for left main spasm. Is it indicated?
    International journal of cardiology, 1996, Volume: 54, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Surgical Procedures; Chest Pain; Co

1996
Chest pain in an aspirin-sensitive asthmatic patient. Eosinophilic esophagitis causing esophageal dysmotility.
    Chest, 1996, Volume: 110, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Chest Pain; Eosinophilia; Esophagea

1996
If I woke with central chest pain....
    Lancet (London, England), 1996, Volume: 348 Suppl 1

    Topics: Aspirin; Attitude to Health; Cardiology; Chest Pain; Coronary Disease; Hospitalization; Humans; Pati

1996
Physical activity, dyspnea, and chest pain before and after coronary artery bypass grafting in relation to a history of diabetes.
    Diabetes care, 1998, Volume: 21, Issue:10

    Topics: Activities of Daily Living; Aspirin; Chest Pain; Coronary Artery Bypass; Diabetic Angiopathies; Dipy

1998
Prevalence of aspirin use among patients calling 9-1-1 for chest pain.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1998, Volume: 5, Issue:12

    Topics: Acute Disease; Adult; Aged; Aspirin; Chest Pain; Cross-Sectional Studies; Drug Utilization; Emergenc

1998
[Acute myocardial infarction: time delay from onset of pain to hospital presentation and thrombolysis].
    Schweizerische medizinische Wochenschrift, 2000, May-06, Volume: 130, Issue:18

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspirin; Chest Pain; Coronary Disease; Female; Hospital

2000
Chest pain rule-out MI clinical pathway saves $183,000.
    Hospital case management : the monthly update on hospital-based care planning and critical paths, 1999, Volume: 7, Issue:12

    Topics: Aspirin; Chest Pain; Colorado; Cost Savings; Critical Pathways; Diagnosis, Differential; Exercise Te

1999
A study of the use of aspirin by general practitioners in suspected myocardial infarction.
    Irish medical journal, 2001, Volume: 94, Issue:2

    Topics: Adult; Aged; Angina, Unstable; Aspirin; Chest Pain; Data Collection; Drug Utilization; Family Practi

2001
Coronary stent deployment in situs inversus.
    Heart (British Cardiac Society), 2001, Volume: 86, Issue:5

    Topics: Aged; Aspirin; Chest Pain; Clopidogrel; Coronary Artery Disease; Dextrocardia; Electrocardiography;

2001
Suppression of eicosanoid biosynthesis during coronary angioplasty by fish oil and aspirin.
    Circulation, 1991, Volume: 84, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Chest Pain; Eicosanoids; Epoprostenol; Fish Oils; Humans; M

1991
Early use of aspirin.
    Lancet (London, England), 1990, Feb-24, Volume: 335, Issue:8687

    Topics: Aspirin; Chest Pain; Humans; Myocardial Infarction; Time Factors

1990
Differences in bleeding time, aspirin sensitivity and adrenaline between acute myocardial infarction and unstable angina.
    Cardiovascular research, 1990, Volume: 24, Issue:1

    Topics: Aged; Angina Pectoris; Angina, Unstable; Aspirin; Bleeding Time; Blood Platelets; Chest Pain; Epinep

1990