aspirin has been researched along with Chemical and Drug Induced Liver Injury in 131 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to investigate the frequency of anemia and hepatotoxicity associated with aspirin use in patients with acute rheumatic fever." | 8.02 | Aspirin-induced hepatotoxicity and anemia in children with acute rheumatic fever. ( Altay, D; Arslan, D; Baykan, A; Pamukçu, Ö; Üzüm, K, 2021) |
| "Acute hepatic decompensation and encephalopathy may occur as a consequence of aspirin hepatoxicity in JRA and justify sequential observations of liver function tests and salicylate levels in such patients." | 5.26 | Hepatoxicity with encephalopathy associated with aspirin therapy in rheumatoid arthritis. ( Crain, JD; Gelfand, EW; Grand, RJ; Ulshen, MH, 1978) |
| " This case suggests that disseminated intravascular coagulation, and its rare association with hepatotoxicity, is a potentially fatal side effect of aspirin therapy." | 5.26 | Aspirin hepatotoxicity and disseminated intravascular coagulation. ( Bennett, RM; Sbarbaro, JA, 1977) |
| " Paracetamol and aspirin were used to induce hepatotoxicity and gastric ulcer in rats, respectively." | 4.12 | Evaluation of Hepatoprotective and Gastroprotective Activities of Paspalidium flavidum Leaves Extract in Experimental Animal Models. ( Ahsan, H; Anjum, I; Ismail, S; Kahrizi, D; Movafagh, A; Naveed Mushtaq, M; Ramzan, HM; Razzaq, A; Shabbir, U; Shoukat, A, 2022) |
| "The aim of this study was to investigate the frequency of anemia and hepatotoxicity associated with aspirin use in patients with acute rheumatic fever." | 4.02 | Aspirin-induced hepatotoxicity and anemia in children with acute rheumatic fever. ( Altay, D; Arslan, D; Baykan, A; Pamukçu, Ö; Üzüm, K, 2021) |
| "Current guidelines offer a choice of P2Y12 receptor antagonist among clopidogrel, prasugrel or ticagrelor on top of aspirin (ASA) for dual antiplatelet therapy (DAPT) in patients after acute coronary syndromes (ACS)." | 3.79 | Gastrointestinal adverse events after dual antiplatelet therapy: clopidogrel is safer than ticagrelor, but prasugrel data are lacking or inconclusive. ( Can, MM; Dinicolantonio, JJ; Kuliczkowski, W; Pershukov, IV; Serebruany, VL, 2013) |
| " An objective causality assessment suggested that the liver hematoma was possibly related to the combination of clopidogrel and aspirin." | 3.78 | Dual antiplatelet agent-induced spontaneous liver hematoma. ( Darwish, OS; Iqbal, E, 2012) |
| "Liver function tests, including serum alanine aminotransferase (ALT) activity, serum bilirubin, alkaline phosphatase, serum proteins, blood ammonia levels and intravenous glucose utilization, were monitored in 50 children with acute rheumatic fever receiving anti-rheumatic doses of aspirin." | 3.68 | Hepatotoxicity of high dose salicylate therapy in acute rheumatic fever. ( Ben-Musa, AA; Chugh, JC; Mehta, HC; Shembesh, AH; Singh, H, 1992) |
| " Documentation is derived from clinical trials, post-marketing surveillance, special studies, and spontaneous reports of adverse drug reactions from foreign countries." | 2.66 | Worldwide safety experience with diclofenac. ( Catalano, MA, 1986) |
| "Since its introduction in the United States in 1974, ibuprofen (Motrin, Upjohn) has been shown to be safe and effective for the treatment of pain, dysmenorrhea, inflammation, and fever." | 2.65 | Safety profile: fifteen years of clinical experience with ibuprofen. ( Royer, GL; Seckman, CE; Welshman, IR, 1984) |
| " However, severe and numerous adverse events are associated with vismodegib use." | 2.52 | Cholestatic hepatic injury associated with vismodegib, aspirin, and naproxen use: a case study and review of vismodegib safety. ( Ash, MM; Jolly, PS, 2015) |
| "However, some patients may develop acute liver failure and successful orthotopic liver transplantation may be undertaken in such patients." | 2.42 | Hepatocellular damage from non-steroidal anti-inflammatory drugs. ( Dargan, PI; Jones, AL; O'Connor, N, 2003) |
| "Fever and pain are the most common issues in pediatric patient management." | 2.36 | Use of antipyretic analgesics in the pediatric patient. ( Gladtke, E, 1983) |
| "10 Phenylbutazone may cause liver injury and other analgesics can cause hypersensitivity reactions in which the liver is involved." | 2.36 | Hepatotoxicity of mild analgesics. ( Prescott, LF, 1980) |
| " However, administration of aspirin causes toxic effects, especially in the stomach and liver." | 1.46 | Nullification of aspirin induced gastrotoxicity and hepatotoxicity by prior administration of wheat germ oil in Mus musculus: histopathological, ultrastructural and molecular studies. ( Hamad, SR; Mohamed, HRH, 2017) |
| "Aspirin intake was associated with reduced risk for sinusoidal lesions (P = ." | 1.35 | Risk factors for chemotherapy-associated liver injuries: A multivariate analysis of a group of 146 patients with colorectal metastases. ( Beauchet, A; Benoist, S; Brouquet, A; Julie, C; Nordlinger, B; Penna, C; Rougier, P, 2009) |
| "The hepatotoxicity of acetaminophen (APAP) overdose depends on metabolic activation to a toxic reactive metabolite via hepatic mixed function oxidase." | 1.28 | Acetaminophen hepatotoxicity: is there a role for prostaglandin synthesis? ( Ben-Zvi, Z; Danon, A; Katz, S; Weissman-Teitellman, B, 1990) |
| "Two children with rheumatic fever developed anicteric hepatitis while on high-dose aspirin therapy." | 1.27 | Salicylate hepato toxicity in rheumatic fever. ( Ahmad, MS; Hamdan, JA; Sa'di, AR, 1983) |
| "The existence of hepatic involvement in systemic lupus erythematosus (SLE) is still contested in the literature." | 1.26 | Hepatic involvement in systemic lupus erythematosus. A case report. ( Forman, MB; Gear, AJ; Levy, H; Ninin, DT, 1981) |
| "Oral aspirin therapy was started at a dosage of 100 mg/kg/day, every six hours." | 1.26 | Salicylate hepatitis: a complication of the treatment of Kawasaki's disease. ( Bertino, JS; Reed, MD; Speck, WT; Willis, ED, 1981) |
| "The charts of 238 patients with systemic lupus erythematosus (SLE) were reviewed." | 1.26 | The spectrum of liver disease in systemic lupus erythematosus. Report of 33 histologically-proved cases and review of the literature. ( Anuras, S; LaBrecque, DR; Runyon, BA, 1980) |
| " It returned to normal after withdrawal of acetylsalicylic acid in 3 cases, after decrease of the dosage in 2 cases and on the same dosage in 1 case." | 1.26 | [The value of serum salicylate determination in patients with rheumatoid arthritis (author's transl)]. ( Chen, HL; Han, SH; Lan, JL; Wang, WC; Wong, W; Wu, HS, 1980) |
| "Aspirin was discontinued and ibuprofen, 600 mg four times daily, begun." | 1.26 | Aspirin hepatotoxicity. ( Hindin, BI; Kanada, SA; Kolling, WM, 1978) |
| "Acute hepatic decompensation and encephalopathy may occur as a consequence of aspirin hepatoxicity in JRA and justify sequential observations of liver function tests and salicylate levels in such patients." | 1.26 | Hepatoxicity with encephalopathy associated with aspirin therapy in rheumatoid arthritis. ( Crain, JD; Gelfand, EW; Grand, RJ; Ulshen, MH, 1978) |
| " This case suggests that disseminated intravascular coagulation, and its rare association with hepatotoxicity, is a potentially fatal side effect of aspirin therapy." | 1.26 | Aspirin hepatotoxicity and disseminated intravascular coagulation. ( Bennett, RM; Sbarbaro, JA, 1977) |
| "A case of hepatotoxicity and encephalopathy (Reye's syndrome?) associated with salicylate therapy is presented and the aetiology of this syndrome is discussed." | 1.25 | Acute liver failure and encephalopathy (Reye's syndrome?) during salicylate therapy. ( Koivikko, A; Mäkelä, AL; Sillanpää, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (63.36) | 18.7374 |
| 1990's | 16 (12.21) | 18.2507 |
| 2000's | 9 (6.87) | 29.6817 |
| 2010's | 18 (13.74) | 24.3611 |
| 2020's | 5 (3.82) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Morgan, RE | 2 |
| Trauner, M | 1 |
| van Staden, CJ | 2 |
| Lee, PH | 1 |
| Ramachandran, B | 1 |
| Eschenberg, M | 1 |
| Afshari, CA | 2 |
| Qualls, CW | 1 |
| Lightfoot-Dunn, R | 1 |
| Hamadeh, HK | 2 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Ismail, S | 1 |
| Naveed Mushtaq, M | 1 |
| Shabbir, U | 1 |
| Razzaq, A | 1 |
| Ramzan, HM | 1 |
| Shoukat, A | 1 |
| Ahsan, H | 1 |
| Movafagh, A | 1 |
| Kahrizi, D | 1 |
| Anjum, I | 1 |
| Baumann, L | 1 |
| Holbech, H | 1 |
| Schmidt-Posthaus, H | 1 |
| Moissl, AP | 1 |
| Hennies, M | 1 |
| Tiedemann, J | 1 |
| Weltje, L | 1 |
| Segner, H | 1 |
| Braunbeck, T | 1 |
| Chang, JH | 1 |
| Sangaraju, D | 1 |
| Liu, N | 1 |
| Jaochico, A | 1 |
| Plise, E | 1 |
| Fasbender, F | 1 |
| Obholzer, M | 1 |
| Metzler, S | 1 |
| Stöber, R | 1 |
| Hengstler, JG | 1 |
| Watzl, C | 1 |
| Gökçe, AB | 1 |
| Eren, B | 1 |
| Sağır, D | 1 |
| Demirel Yılmaz, B | 1 |
| Altay, D | 1 |
| Pamukçu, Ö | 1 |
| Baykan, A | 1 |
| Üzüm, K | 1 |
| Arslan, D | 1 |
| Mohamed, HRH | 1 |
| Hamad, SR | 1 |
| Yiannakopoulou, E | 1 |
| Serebruany, VL | 1 |
| Dinicolantonio, JJ | 1 |
| Can, MM | 1 |
| Pershukov, IV | 1 |
| Kuliczkowski, W | 1 |
| Zhang, X | 1 |
| Ouyang, J | 1 |
| Thung, SN | 1 |
| Raza, A | 1 |
| Vierling, J | 1 |
| Hussain, KB | 1 |
| Ash, MM | 1 |
| Jolly, PS | 1 |
| Cao, Z | 1 |
| Liu, S | 1 |
| Niu, J | 1 |
| Wei, B | 1 |
| Xu, J | 1 |
| Bouzenna, H | 1 |
| Samout, N | 1 |
| Amani, E | 1 |
| Mbarki, S | 1 |
| Tlili, Z | 1 |
| Rjeibi, I | 1 |
| Elfeki, A | 1 |
| Talarmin, H | 1 |
| Hfaiedh, N | 1 |
| Brouquet, A | 1 |
| Benoist, S | 1 |
| Julie, C | 1 |
| Penna, C | 1 |
| Beauchet, A | 1 |
| Rougier, P | 1 |
| Nordlinger, B | 1 |
| Darwish, OS | 1 |
| Iqbal, E | 1 |
| LARSON, EJ | 1 |
| SEPULVEDA, B | 1 |
| LANDA, L | 1 |
| LOCKEY, SD | 1 |
| EDER, H | 1 |
| O'Connor, N | 1 |
| Dargan, PI | 1 |
| Jones, AL | 1 |
| Andres, E | 1 |
| Yates, AB | 1 |
| deShazo, RD | 1 |
| FISHGOLD, JT | 1 |
| FIELD, J | 1 |
| HALL, VE | 1 |
| Katira, R | 1 |
| Chauhan, A | 1 |
| More, RS | 1 |
| Manov, I | 1 |
| Motanis, H | 1 |
| Frumin, I | 1 |
| Iancu, TC | 1 |
| Herrgesell, JD | 1 |
| Kolts, BE | 1 |
| Langfitt, M | 1 |
| Hamdan, JA | 1 |
| Ahmad, MS | 1 |
| Sa'di, AR | 1 |
| Royer, GL | 1 |
| Seckman, CE | 1 |
| Welshman, IR | 1 |
| Baum, J | 1 |
| Hanks, GW | 1 |
| Gladtke, E | 1 |
| Ehrlich, G | 1 |
| Cupit, GC | 1 |
| Tamura, T | 1 |
| Prescott, LF | 2 |
| Mariani, L | 1 |
| Baratelli, M | 1 |
| von Mühlendahl, KE | 1 |
| Schmidt, RE | 1 |
| Forman, MB | 1 |
| Levy, H | 1 |
| Gear, AJ | 1 |
| Ninin, DT | 1 |
| Harbison, RD | 1 |
| Bertino, JS | 1 |
| Willis, ED | 1 |
| Reed, MD | 1 |
| Speck, WT | 1 |
| Chesta, J | 1 |
| Orellana Alcalde, JM | 1 |
| Mehana, D | 1 |
| Runyon, BA | 1 |
| LaBrecque, DR | 1 |
| Anuras, S | 1 |
| Girot, R | 1 |
| Jacques, C | 1 |
| Besson, M | 1 |
| Lavaud, J | 1 |
| Lan, JL | 1 |
| Wong, W | 1 |
| Wang, WC | 1 |
| Wu, HS | 1 |
| Chen, HL | 1 |
| Han, SH | 1 |
| Polunina, TE | 1 |
| Fomichev, VI | 1 |
| Vasil'ev, AP | 1 |
| Lee, M | 1 |
| Schenker, S | 1 |
| Barriault, C | 1 |
| Audet, M | 1 |
| Yousef, IM | 1 |
| Tuchweber, B | 1 |
| Hilburn, RB | 1 |
| Bookstaver, D | 1 |
| Whitlock, WL | 1 |
| López-Morante, AJ | 1 |
| Sáez-Royuela, F | 1 |
| Díez-Sánchez, V | 1 |
| Martín-Lorente, JL | 1 |
| Yuguero, L | 1 |
| Ojeda, C | 1 |
| D'Abrigeon, G | 1 |
| Blanc, P | 1 |
| Durand, L | 1 |
| Larrey, D | 1 |
| Michel, H | 1 |
| Elzouki, AN | 1 |
| Lindgren, S | 1 |
| Trost, LC | 1 |
| Lemasters, JJ | 1 |
| McGoldrick, MD | 1 |
| Bailie, GR | 1 |
| Matzke, GR | 1 |
| Ennamany, R | 1 |
| Bingen, A | 1 |
| Creppy, EE | 1 |
| Kretz, O | 1 |
| Gut, JP | 1 |
| Dubuisson, L | 1 |
| Balabaud, C | 1 |
| Bioulac Sage, P | 1 |
| Kirn, A | 1 |
| Meyer, MI | 1 |
| Kuhn, M | 1 |
| Bühler, H | 1 |
| Bertschinger, P | 1 |
| Fiorucci, S | 1 |
| Santucci, L | 1 |
| Antonelli, E | 1 |
| Distrutti, E | 1 |
| Del Sero, G | 1 |
| Morelli, O | 1 |
| Romani, L | 1 |
| Federici, B | 1 |
| Del Soldato, P | 1 |
| Morelli, A | 1 |
| Chen, TC | 1 |
| Ng, KF | 1 |
| Jeng, LB | 1 |
| Yeh, TS | 1 |
| Chen, CM | 1 |
| Hollister, LE | 1 |
| Damus, PS | 1 |
| Wallace, GA | 1 |
| Bulugahapitiya, DT | 1 |
| Hebron, B | 1 |
| Beck, PR | 1 |
| Tolot, F | 1 |
| Prost, G | 1 |
| Guignot, B | 1 |
| Pelletier, M | 1 |
| Kanada, SA | 1 |
| Kolling, WM | 1 |
| Hindin, BI | 1 |
| Lai, MY | 1 |
| Sung, JL | 1 |
| Lin, WS | 1 |
| How, SW | 1 |
| Yu, JY | 1 |
| Wang, TH | 1 |
| Chen, DS | 1 |
| Kiechle, FL | 1 |
| Kaplan, AG | 1 |
| Bernstein, J | 1 |
| Knudsen, FU | 1 |
| Petty, BG | 1 |
| Zahka, KG | 1 |
| Bernstein, MT | 1 |
| Ulshen, MH | 1 |
| Grand, RJ | 1 |
| Crain, JD | 1 |
| Gelfand, EW | 1 |
| Schaller, JG | 1 |
| Travers, RL | 1 |
| Hughes, GR | 1 |
| Halla, JT | 1 |
| Koch-Weser, J | 1 |
| Sbarbaro, JA | 1 |
| Bennett, RM | 1 |
| Bernstein, BH | 1 |
| Singsen, BH | 1 |
| King, KK | 1 |
| Hanson, V | 1 |
| Soares, JO | 1 |
| Aguas, AP | 1 |
| Moura-Nunes, JF | 1 |
| Athreya, BH | 2 |
| Iancu, T | 2 |
| Elian, E | 2 |
| Wilson, JR | 1 |
| Fossati, C | 1 |
| Garber, E | 1 |
| Craig, RM | 1 |
| Bahu, RM | 1 |
| Sillanpää, M | 1 |
| Mäkelä, AL | 1 |
| Koivikko, A | 1 |
| Levy, G | 1 |
| Yaffe, SJ | 1 |
| Zucker, P | 1 |
| Daum, F | 1 |
| Cohen, MI | 1 |
| Sekanina, M | 1 |
| Frána, L | 1 |
| Stöger, F | 1 |
| Ricks, WB | 1 |
| Singh, H | 1 |
| Chugh, JC | 1 |
| Shembesh, AH | 1 |
| Ben-Musa, AA | 1 |
| Mehta, HC | 1 |
| De Leeuw, P | 1 |
| Lefebvre, C | 1 |
| Tomasi, JP | 1 |
| Rahier, J | 1 |
| Geubel, A | 1 |
| Toft, E | 1 |
| Vyberg, M | 1 |
| Therkelsen, K | 1 |
| Ben-Zvi, Z | 1 |
| Weissman-Teitellman, B | 1 |
| Katz, S | 1 |
| Danon, A | 1 |
| Schlegel, SI | 1 |
| Paulus, HE | 1 |
| Qamar, MA | 1 |
| Alam, SM | 1 |
| Riggs, BS | 1 |
| Kulig, K | 1 |
| Rumack, BH | 1 |
| Catalano, MA | 1 |
| Jakubowska, D | 1 |
| Grzebieniak-Kopieczna, E | 1 |
| O'Brien, WM | 1 |
| Bagby, GF | 1 |
| Fanelli, V | 1 |
| Paolinelli, E | 1 |
| Piergiacomi, G | 1 |
| David, DS | 1 |
| Steere, AC | 1 |
| Pi-Sunyer, XF | 1 |
| Sakai, S | 1 |
| Clark, SB | 1 |
| Koppes, GM | 1 |
| Arnett, FC | 1 |
| Gitlin, N | 1 |
| Dietrich, B | 1 |
| Spektor, F | 1 |
| Cuthbert, MF | 1 |
| Murray, RM | 1 |
| Gorske, AL | 1 |
| Myers, AR | 1 |
| Zimmerman, HJ | 1 |
| Seaman, WE | 2 |
| Ishak, KG | 2 |
| Plotz, PH | 2 |
| Wolfe, JD | 1 |
| Metzger, AL | 1 |
| Goldstein, RC | 1 |
| Goldenberg, DL | 1 |
| Hilton, AM | 1 |
| Dymock, IW | 1 |
| Strauss, RG | 1 |
| McAdams, AJ | 1 |
| Henrard, JC | 1 |
| Russell, AS | 1 |
| Sturge, RA | 1 |
| Smith, MA | 1 |
| Jablońska, A | 1 |
| Urban, J | 1 |
| Okumura, H | 2 |
| Takayama, K | 1 |
| Obayashi, K | 2 |
| Ichikawa, T | 2 |
| Aramaki, T | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Full-Factorial, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Single-Dose Efficacy and Safety Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen, and Naproxen Sodium in Postoperative Dental Pain[NCT05761574] | Phase 3 | 440 participants (Anticipated) | Interventional | 2023-05-22 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
22 reviews available for aspirin and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Pharmacogenomics of acetylsalicylic acid and other nonsteroidal anti-inflammatory agents: clinical implications.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Chemical and Drug I | 2013 |
Histopathologic manifestations of drug-induced hepatotoxicity.
Topics: Aspirin; Cell Death; Chemical and Drug Induced Liver Injury; Hepatocytes; Humans; Immunohistochemist | 2013 |
Cholestatic hepatic injury associated with vismodegib, aspirin, and naproxen use: a case study and review of vismodegib safety.
Topics: Aged; Anilides; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, | 2015 |
Hepatocellular damage from non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Liver Injury; D | 2003 |
Allergic and nonallergic drug reactions.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cephalosporins; Chemical an | 2003 |
Direct thrombin inhibitors: novel antithrombotics on the horizon in the thromboprophylactic management of atrial fibrillation.
Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Azetidines; Benzylamines; Chemic | 2005 |
Hepatotoxicity of anti-inflammatory and analgesic drugs: ultrastructural aspects.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Ster | 2006 |
Aspirin in the treatment of juvenile arthritis.
Topics: Arthritis, Juvenile; Aspirin; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topi | 1983 |
Nonprescription analgesics.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Liver Inj | 1983 |
Use of antipyretic analgesics in the pediatric patient.
Topics: Acetaminophen; Adolescent; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemic | 1983 |
The use of non-prescription analgesics in an older population.
Topics: Acetaminophen; Aged; Analgesics; Aspirin; Blood Coagulation; Chemical and Drug Induced Liver Injury; | 1982 |
Hepatotoxicity of mild analgesics.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Chemical and Drug Induced Liver Injury; Child; Humans; Ph | 1980 |
[Paracetamol: overdose and hepatic lesions].
Topics: Acetaminophen; Aspirin; Chemical and Drug Induced Liver Injury; Fever; Humans; Liver; Necrosis; Pain | 1981 |
Nonnarcotic analgesics: prevalence and estimated economic impact of toxicities.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical | 1997 |
Effective use of analgesic drugs.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ast | 1976 |
The third Lilly Prize Lecture. University of London, January, 1979. The nephrotoxicity and hepatotoxicity of antipyretic analgesics.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Liver Inj | 1979 |
Biochemical and morphological study of the liver injury induced by drugs and chemicals.
Topics: Alkaline Phosphatase; Aspirin; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Halothan | 1979 |
Aspirin, liver, and rheumatic diseases.
Topics: Adolescent; Adult; Arthritis, Juvenile; Arthritis, Rheumatoid; Aspirin; Chemical and Drug Induced Li | 1976 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Cen | 1986 |
Current status of aspirin and acetaminophen intoxication.
Topics: Acetaminophen; Aspirin; Chemical and Drug Induced Liver Injury; Gastrointestinal Diseases; Humans; R | 1987 |
Rare adverse reactions to nonsteroidal antiinflammatory drugs (3).
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; | 1985 |
4 trials available for aspirin and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Safety profile: fifteen years of clinical experience with ibuprofen.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Cell Count; Blood Coagulation Tests; Blood Proteins; Centra | 1984 |
Aspirin in the treatment of juvenile arthritis.
Topics: Arthritis, Juvenile; Aspirin; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topi | 1983 |
Drug therapy. Acetaminophen.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Body Temperature; Chemical and Drug Induced Liver Injury; | 1976 |
Worldwide safety experience with diclofenac.
Topics: Adult; Aged; Aspirin; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Diclo | 1986 |
106 other studies available for aspirin and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Evaluation of Hepatoprotective and Gastroprotective Activities of Paspalidium flavidum Leaves Extract in Experimental Animal Models.
Topics: Acetaminophen; Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Chemical and Drug Induced Liver In | 2022 |
Does hepatotoxicity interfere with endocrine activity in zebrafish (Danio rerio)?
Topics: Acetaminophen; Animals; Aspirin; Chemical and Drug Induced Liver Injury; Endocrine System; Female; H | 2020 |
Comprehensive Evaluation of Bile Acid Homeostasis in Human Hepatocyte Co-Culture in the Presence of Troglitazone, Pioglitazone, and Acetylsalicylic Acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile Acids and Salts; Cells, Cultured; Chemical an | 2019 |
Enhanced activation of human NK cells by drug-exposed hepatocytes.
Topics: Antibodies, Neutralizing; Aspirin; Chemical and Drug Induced Liver Injury; Coculture Techniques; Cyt | 2020 |
A histopathological and stereological study of the effects of acetylsalicylic acid on doxorubicin-induced hepatotoxicity in mice.
Topics: Animals; Antibiotics, Antineoplastic; Aspirin; Chemical and Drug Induced Liver Injury; Doxorubicin; | 2021 |
Aspirin-induced hepatotoxicity and anemia in children with acute rheumatic fever.
Topics: Adolescent; Anemia; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Live | 2021 |
Nullification of aspirin induced gastrotoxicity and hepatotoxicity by prior administration of wheat germ oil in Mus musculus: histopathological, ultrastructural and molecular studies.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Agen | 2017 |
Gastrointestinal adverse events after dual antiplatelet therapy: clopidogrel is safer than ticagrelor, but prasugrel data are lacking or inconclusive.
Topics: Acute Coronary Syndrome; Adenosine; Aspirin; Chemical and Drug Induced Liver Injury; Clinical Trials | 2013 |
Genetics of drug-induced hepatotoxicity toxicity in Gilbert's syndrome.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Chemical and Drug Induced | 2013 |
Severe hepatoxicity caused by aspirin overdose: a case report.
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Drug Overdose; Humans; Liver Failure; Male; Middle | 2015 |
Protective Effects of Pinus halepensis L. Essential Oil on Aspirin-induced Acute Liver and Kidney Damage in Female Wistar Albino Rats.
Topics: Acute Disease; Albinism; Animals; Aspirin; Chemical and Drug Induced Liver Injury; Female; Kidney; K | 2016 |
Risk factors for chemotherapy-associated liver injuries: A multivariate analysis of a group of 146 patients with colorectal metastases.
Topics: Aged; Antineoplastic Agents; Aspirin; Chemical and Drug Induced Liver Injury; Colorectal Neoplasms; | 2009 |
Dual antiplatelet agent-induced spontaneous liver hematoma.
Topics: Aged; Aspirin; Chemical and Drug Induced Liver Injury; Clopidogrel; Coronary Artery Disease; Drug Th | 2012 |
Basic pain relievers. It's wise to use caution.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induc | 2012 |
Adverse drug reaction update.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bupropion; Chemical and Drug Induced Liver Injury; | 2002 |
TOXICITY OF LOW DOSES OF ASPIRIN IN THE CAT.
Topics: Anemia; Animals; Aspirin; Body Weight; Cats; Chemical and Drug Induced Liver Injury; Erythrocyte Cou | 1963 |
[RECENT ACQUISITIONS IN INTERNAL MEDICINE IN RELATION TO: CARDIOLOGY, DERMATOLOGY, GASTROENTEROLOGY, IMMUNOLOGY, NEPHROLOGY AND PNEUMOLOGY. IV. GASTROENTEROLOGY].
Topics: Aspirin; Bile Pigments; Chemical and Drug Induced Liver Injury; Dermatology; Gastroenterology; Gastr | 1963 |
ADVERSE REACTIONS TO DRUGS.
Topics: Anaphylaxis; Anti-Bacterial Agents; Aspirin; Chemical and Drug Induced Liver Injury; Chloramphenicol | 1964 |
CHRONIC TOXICITY STUDIES ON PHENACETIN, N-ACETYL-P-AMINOPHENOL (NAPA) AND ACETYLSALICYLIC ACID ON CATS.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Cats; Chemical and Drug | 1964 |
Drug-induced hepatotoxicity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Liver Injury; Child; Dru | 2003 |
Effect of sodium salicylate and acetylsalicylate on metabolism of rat brain and liver in vitro.
Topics: Animals; Aspirin; Brain; Chemical and Drug Induced Liver Injury; In Vitro Techniques; Liver; Rats; S | 1951 |
Aspirin poisoning in the cat.
Topics: Animals; Aspirin; Cat Diseases; Cats; Chemical and Drug Induced Liver Injury; Gastritis; Male | 1967 |
Drugs and the liver.
Topics: Acetaminophen; Adult; Aspirin; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liv | 1984 |
Salicylate hepato toxicity in rheumatic fever.
Topics: Aspartate Aminotransferases; Aspirin; Chemical and Drug Induced Liver Injury; Child; Child, Preschoo | 1983 |
Primary drug therapy: aspirin vs. the nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Central Nervous System Diseases; Chemical and Drug Ind | 1983 |
[Aspirin-induced abnormality, liver damage induced by antibiotics, fatal drug reaction, and observation of the teeth].
Topics: Abnormalities, Drug-Induced; Adult; Anti-Bacterial Agents; Aspirin; Aurothioglucose; Chemical and Dr | 1980 |
[Salicylate induced disturbances of liver function (author's transl)].
Topics: Alanine Transaminase; Arthritis, Juvenile; Aspartate Aminotransferases; Aspirin; Chemical and Drug I | 1982 |
[Hepatotoxicity of acetylsalicylic acid].
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Diflunisal; Humans | 1982 |
Hepatic involvement in systemic lupus erythematosus. A case report.
Topics: Adult; Alkaline Phosphatase; Aspirin; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; | 1981 |
Acetaminophen as an aspirin substitute: is it safer?
Topics: Acetaminophen; Aspirin; Biotransformation; Cardiomyopathies; Chemical and Drug Induced Liver Injury; | 1980 |
Salicylate hepatitis: a complication of the treatment of Kawasaki's disease.
Topics: Adult; Aspartate Aminotransferases; Aspirin; Chemical and Drug Induced Liver Injury; Humans; L-Lacta | 1981 |
[Acetylsalicylic acid-induced hepatotoxicity].
Topics: Adult; Alkaline Phosphatase; Arthritis, Juvenile; Aspirin; Chemical and Drug Induced Liver Injury; F | 1981 |
The spectrum of liver disease in systemic lupus erythematosus. Report of 33 histologically-proved cases and review of the literature.
Topics: Adolescent; Adult; Aged; Aspirin; Biopsy; Chemical and Drug Induced Liver Injury; Child, Preschool; | 1980 |
[Mechanism of hypoprothrombinemia in aspirin poisoning].
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Female; Humans; Hypoprothrombinemias; Infant | 1980 |
[The value of serum salicylate determination in patients with rheumatoid arthritis (author's transl)].
Topics: Adult; Arthritis, Rheumatoid; Aspirin; Chemical and Drug Induced Liver Injury; Dose-Response Relatio | 1980 |
[The hepatotoxic effect of nonsteroidal anti-inflammatory preparations].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Liver Injury; Dic | 1994 |
Alcohol and analgesics--mix extraordinaire.
Topics: Acetaminophen; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug | 1994 |
Protection by indomethacin against the lethality and hepatotoxicity of phalloidin in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspirin; Chemical and Drug Induced Liver | 1994 |
Comment: angiotension-converting enzyme inhibitor hepatotoxicity: further insights.
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Chemical and Drug Induced Liver Injury; Drug Inte | 1993 |
Aspirin-induced cholestatic hepatitis.
Topics: Aged; Aspirin; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Humans; Male | 1993 |
[Liver cirrhosis and granulomatous hepatitis after prolonged ingestion of lysine acetylsalicylate].
Topics: Aged; Analgesics; Aspirin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; | 1995 |
Granulomatous hepatitis induced by aspirin-kodein analgesics.
Topics: Analgesics; Aspirin; Biopsy; Chemical and Drug Induced Liver Injury; Codeine; Drug Combinations; Gra | 1996 |
The mitochondrial permeability transition: a new pathophysiological mechanism for Reye's syndrome and toxic liver injury.
Topics: Animals; Aspirin; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Cyclosporine; Male; Memb | 1996 |
Clinical consequences of nonnarcotic analgesic use.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 1997 |
Aspirin and heparin prevent hepatic blood stasis and thrombosis induced by the toxic glycoprotein Bolesatine in mice.
Topics: Agglutination; Animals; Aspirin; Blood Platelets; Chemical and Drug Induced Liver Injury; Dose-Respo | 1998 |
[Ticlopidine-induced cholestasis].
Topics: Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Chemical and Drug Induced Liver Injury; Cholestas | 1999 |
NO-aspirin protects from T cell-mediated liver injury by inhibiting caspase-dependent processing of Th1-like cytokines.
Topics: Amino Acid Chloromethyl Ketones; Animals; Aspirin; Caspase 1; Caspase 3; Caspase Inhibitors; Caspase | 2000 |
Aspirin-related hepatotoxicity in a child after liver transplant.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Liver Injury; Child, Pre | 2001 |
Immunologic measurement of antithrombin III-heparin cofactor and alpha2 macroglobulin in disseminated intravascular coagulation and hepatic failure coagulopathy.
Topics: Alpha-Globulins; Antithrombin III; Antithrombins; Aspirin; Blood Platelets; Chemical and Drug Induce | 1975 |
Salicylate hepatitis with acidosis in an infant.
Topics: Acidosis; Aspirin; Chemical and Drug Induced Liver Injury; Humans; Hydrogen-Ion Concentration; Infan | 1979 |
[Multiple manifestations of intolerance of a combination of anti-inflammatory drugs. Role of phenylbutazone].
Topics: Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Duodenal Ulcer; Erythema; | 1975 |
Aspirin hepatotoxicity.
Topics: Adolescent; Adult; Aging; Aspirin; Chemical and Drug Induced Liver Injury; Child; Female; Humans; Li | 1978 |
Intramitochondrial inclusions in hepatocytes.
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Crystallization; Humans; Liver Diseases; Mitochondr | 1978 |
[Acetylsalicylic acid and liver damage].
Topics: Arthritis, Juvenile; Aspirin; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Femal | 1978 |
Aspirin hepatitis associated with encephalopathy.
Topics: Adolescent; Aspirin; Biopsy; Chemical and Drug Induced Liver Injury; Electroencephalography; Female; | 1978 |
Hepatoxicity with encephalopathy associated with aspirin therapy in rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Arthritis, Rheumatoid; Aspirin; Biopsy; Brain Diseases; Chemical an | 1978 |
Chronic salicylate administration in juvenile rheumatoid arthritis: aspirin "hepatitis" and its clinical significance.
Topics: Adolescent; Arthritis, Juvenile; Aspirin; Chemical and Drug Induced Liver Injury; Child; Child, Pres | 1978 |
Salicylate hepatotoxicity in systemic lupus erythematosus: a common occurrence?
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Humans; Liver Function Tests; Lupus Erythematosus, | 1978 |
Aspirin hepatotoxicity and disseminated intravascular coagulation.
Topics: Adolescent; Arthritis, Juvenile; Aspirin; Biopsy; Chemical and Drug Induced Liver Injury; Disseminat | 1977 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 23--1977.
Topics: Acetaminophen; Acute Disease; Adolescent; Arthritis, Juvenile; Aspirin; Brain Death; Brain Edema; Ch | 1977 |
Aspirin-induced hepatotoxicity and its effect on juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Aspartate Aminotransferases; Aspirin; Chemical and Drug Induced Liver Injury; C | 1977 |
Hepatic changes induced by lysine acetylsalicylate.
Topics: Animals; Aspirin; Chemical and Drug Induced Liver Injury; Humans; Liver Diseases; Lysine; Mice | 1977 |
Letter: Aspirin hepatitis.
Topics: Arthritis, Juvenile; Aspirin; Chemical and Drug Induced Liver Injury; Humans | 1976 |
Ultrastructural changes in aspirin hepatotoxicity.
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Child; Endoplasmic Reticulum; Humans; Liver; Male; | 1976 |
Aspirin hepatotoxicity in adults with rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Aspirin; Chemical and Drug Induced Liver Injury; Female; Humans; Middl | 1976 |
[Side and toxic effects of salicylates].
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Female; Heart Diseases; Humans; Kidney Diseases; Ma | 1976 |
Letter: Aspirin hepatotoxicity.
Topics: Adult; Aspirin; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Common Cold; Female; Headach | 1975 |
Acute liver failure and encephalopathy (Reye's syndrome?) during salicylate therapy.
Topics: Acute Disease; Adolescent; Aspirin; Brain Diseases; Chemical and Drug Induced Liver Injury; Female; | 1975 |
Clinical implications of salicylate-induced liver damage.
Topics: Alanine Transaminase; Arthritis, Juvenile; Aspartate Aminotransferases; Aspirin; Chemical and Drug I | 1975 |
Aspirin hepatitis.
Topics: Adolescent; Anemia, Sickle Cell; Arthritis, Juvenile; Aspartate Aminotransferases; Aspirin; Chemical | 1975 |
[Liver damage in long-term treatment with salicylates in children].
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Child; Humans; Time Factors | 1975 |
Letter: Salicylate hepatotoxicity in Reiter's syndrome.
Topics: Adolescent; Arthritis, Reactive; Aspirin; Chemical and Drug Induced Liver Injury; Humans; Liver; Mal | 1976 |
Hepatotoxicity of high dose salicylate therapy in acute rheumatic fever.
Topics: Acute Disease; Adolescent; Aspirin; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; | 1992 |
[Severe hepatitis with encephalopathy induced by acetylsalicylic acid in a case of lupus erythematosus disseminatus].
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Female; Hepatic Encephalopathy; Humans; Lupus Eryth | 1992 |
Diltiazem-induced granulomatous hepatitis.
Topics: Aged; Aspirin; Atenolol; Chemical and Drug Induced Liver Injury; Diltiazem; Female; Granuloma; Human | 1991 |
Acetaminophen hepatotoxicity: is there a role for prostaglandin synthesis?
Topics: Acetaminophen; Animals; Aspirin; Chemical and Drug Induced Liver Injury; Glutathione; Hexobarbital; | 1990 |
A histopathological study of analgesic hepatotoxicity in rabbit.
Topics: Acetaminophen; Acute Disease; Animals; Aspirin; Chemical and Drug Induced Liver Injury; Cholangitis; | 1988 |
[Salicylate hepatotoxicity].
Topics: Adult; Aspirin; Chemical and Drug Induced Liver Injury; Child; Drug Hypersensitivity; Humans; Liver | 1986 |
[Hepatotoxicity of non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Child; Female; Humans; In | 1985 |
Aspirin-induced hypoglycaemia in a patient on haemodialysis.
Topics: Adult; Aspirin; Chemical and Drug Induced Liver Injury; Humans; Hypoglycemia; Kidney Failure, Chroni | 1971 |
Editorial: Does aspirin harm the liver?
Topics: Arthritis, Rheumatoid; Aspirin; Biopsy; Chemical and Drug Induced Liver Injury; Dose-Response Relati | 1974 |
Salicylate hepatotoxicity.
Topics: Adult; Arthritis, Juvenile; Aspartate Aminotransferases; Aspirin; Biopsy; Chemical and Drug Induced | 1974 |
Salicylate hepatitis. A case report.
Topics: Adolescent; Aspartate Aminotransferases; Aspirin; Bilirubin; Biopsy; Calcium; Chemical and Drug Indu | 1974 |
Adverse reactions to non-steroidal antirheumatic drugs.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Chemical and Drug Induced Liv | 1974 |
Dependance on analgesics in analgesic nephropathy.
Topics: Adult; Aged; Analgesics; Aspirin; Caffeine; Chemical and Drug Induced Liver Injury; Codeine; Female; | 1973 |
Aspirin-induced abnormalities of liver function.
Topics: Alanine Transaminase; Alkaline Phosphatase; Anemia, Sickle Cell; Arthritis, Juvenile; Aspartate Amin | 1973 |
Editorial: Aspirin-induced hepatic injury.
Topics: Animals; Aspirin; Chemical and Drug Induced Liver Injury; Child; Drug Hypersensitivity; Humans; Live | 1974 |
Aspirin-induced hepatotoxicity in patients with systemic lupus erythematosus.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Aspirin; Biopsy; Chemical and Drug Induced | 1974 |
Aspirin hepatitis.
Topics: Adult; Aspirin; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Function Tests; | 1974 |
Letter: Aspirin and hepatotoxicity: addendum.
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Female; Humans | 1974 |
Letter: Aspirin hepatotoxicity.
Topics: Adolescent; Aspirin; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Lupus Erythemato | 1974 |
Letter: Aspirin-induced abnormalities of liver function.
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Humans; Liver | 1974 |
Letter: Aspirin hepatotoxicity.
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Diseases; Liver Function Tests | 1974 |
Arthritis, aspirin, and coma.
Topics: Arthritis, Juvenile; Aspirin; Brain Edema; Chemical and Drug Induced Liver Injury; Child, Preschool; | 1970 |
[Current analgesic anti-inflammatory drugs].
Topics: Analgesics; Aniline Compounds; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver In | 1970 |
Reye's syndrome and salicylate intoxication.
Topics: Adipose Tissue; Aspirin; Brain Diseases; Chemical and Drug Induced Liver Injury; Fatty Liver; Humans | 1970 |
Serum transaminases during salicylate therapy.
Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Alkaline Phosphatase; Arthritis, Juvenil | 1971 |
[A case of hypoglycemia of hepatic origin during treatment with polopyrine].
Topics: Arthritis, Juvenile; Aspirin; Chemical and Drug Induced Liver Injury; Child; Female; Humans; Hypogly | 1969 |
[Chronic toxic hepatitis caused by aspirin].
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Humans; Male; Middle Aged | 1965 |
[Hepatic damage due to aspirin].
Topics: Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Aspirin; Chemical and Drug Ind | 1966 |