aspirin has been researched along with Chemical Dependence in 175 studies
Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Self-reported use or consumption of tobacco, marijuana, cocaine, aspirin, and other nonsteroidal antiinflammatory drugs during pregnancy." | 7.69 | Persistent pulmonary hypertension of the newborn and smoking and aspirin and nonsteroidal antiinflammatory drug consumption during pregnancy. ( Allred, EN; Cohen, A; Epstein, MF; Leviton, A; Pagano, M; Sullivan, KF; Van Marter, LJ, 1996) |
| "The abuse of the combination drug containing butalbital 50 mg, aspirin 325 mg and caffeine 40 mg (or BAC), is commonly recognized by headache specialists as causing headaches." | 7.68 | A protocol for butalbital, aspirin and caffeine (BAC) detoxification in headache patients. ( Sands, GH, 1990) |
| " However, it is still not clear, how aspirin affects expression of major platelet receptors in chronic drug users with coronary artery disease, especially those recovering in the methadone clinic maintenance program." | 5.09 | Paradoxical activation of major platelet receptors in the methadone-maintained patients after single pill of aspirin. ( Callahan, KP; Malinin, AI; Serebruany, VL, 2001) |
| "Clinical and endoscopic findings as well as Helicobacter pylori status, gastric secretion analysis, serum gastrin levels, nonsteroidal anti-inflammatory drug (NSAID) use, and objective testing of aspirin use by platelet cyclooxygenase activity were studied in 60 consecutive refractory patients with peptic ulcer and 54 matched nonrefractory controls." | 3.69 | Risk factors associated with refractory peptic ulcers. ( Esteva, F; Lanas, AI; Remacha, B; Sáinz, R, 1995) |
| "Self-reported use or consumption of tobacco, marijuana, cocaine, aspirin, and other nonsteroidal antiinflammatory drugs during pregnancy." | 3.69 | Persistent pulmonary hypertension of the newborn and smoking and aspirin and nonsteroidal antiinflammatory drug consumption during pregnancy. ( Allred, EN; Cohen, A; Epstein, MF; Leviton, A; Pagano, M; Sullivan, KF; Van Marter, LJ, 1996) |
| "Regular use of analgesic drugs containing phenacetin is associated with an increased risk of hypertension and mortality and morbidity due to cardiovascular disease, as well as an increased risk of mortality due to cancer and urologic or renal disease." | 3.68 | An epidemiologic study of abuse of analgesic drugs. Effects of phenacetin and salicylate on mortality and cardiovascular morbidity (1968 to 1987) ( Dubach, UC; Rosner, B; Stürmer, T, 1991) |
| "The abuse of the combination drug containing butalbital 50 mg, aspirin 325 mg and caffeine 40 mg (or BAC), is commonly recognized by headache specialists as causing headaches." | 3.68 | A protocol for butalbital, aspirin and caffeine (BAC) detoxification in headache patients. ( Sands, GH, 1990) |
| " The case was complicated due to a history of aspirin usage, marked obesity, and thrombocytopenia." | 3.67 | Femoral artery laceration complicating an intertrochanteric hip fracture: a multi-disciplinary therapeutic problem. ( Chmell, S; Haid, S; Milewski, S; Moss, GD; Pillars, JR, 1985) |
| "Two patients are reported in whom repeated postoperative hematomas appeared to be secondary to aspirin-induced platelet defect." | 3.66 | Surgical postoperative bleeding associated with aspirin ingestion. Report of two cases. ( Bell, W; Long, DM; Merriman, E, 1979) |
| " There were five chronic alcoholics, one aspirin abuser, one severely burned patient, and one patient with sepsis." | 3.65 | Gastric devascularization: an alternate approach to the surgical treatment of massive, diffuse hemorrhage from gastritis. ( Aust, JB; McFee, AS; Rittenhouse, M, 1976) |
| "Analgesic nephropathy is part of a wider clinical syndrome associated with the abuse of APC compounds, that is, a minimum total intake of 2 kg of aspirin or phenacetin." | 3.65 | Analgesic nephropathy. ( Nanra, RS, 1976) |
| " To clarify this matter the study investigated the effects of aspirin alone and in combination with caffeine on mood and cardiovascular parameters before, during, and after pain induction through mechanical stimulation." | 2.70 | [Experimental study of the effect of acetylsalicylic acid combined with caffeine regarding possible abuse potential]. ( Hüppe, A; Janke, W, 2001) |
| "Considering parachute as a "home-made" dosage form, we have applied the dissolution testing to characterize the dissolution performance of a substance wrapped into a parachute and to characterize whether a parachute represents an immediate-release form or not." | 1.48 | Parachuting psychoactive substances: Pharmacokinetic clues for harm reduction. ( Baumevieille, M; Daveluy, A; Géniaux, H; Guéroult, P; Haramburu, F; Lazès-Charmetant, A; Létinier, L; Matta, MN, 2018) |
| "Norjizak is a new drug abused in the past few years in Iran with symptoms and complications distinct from other common forms of drug and characterized by higher rate of mortality." | 1.42 | A tentative component analysis of Norjizak: A new abused drug in Iran. ( Farhoudian, A; Fekri, M; Movaghar, AR; Rahimzadeh, S; Sadeghi, M; Sefatian, S; Vishteh, HR, 2015) |
| "We described the cardioembolic (Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack [CHADS2]/Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack, Vascular disease, Age 65-75, Sex category i." | 1.40 | Stroke and bleeding risk co-distribution in real-world patients with atrial fibrillation: the Euro Heart Survey. ( Crijns, HJ; Iorio, A; Lip, GY; Marcucci, M; Nieuwlaat, R; Pisters, R, 2014) |
| "Spontaneous aortic thrombosis is rare." | 1.35 | Aortic thrombosis in infancy. ( Mehta, AV; Teixeira, OH, 2009) |
| "We estimated the proportion of miscarriage to be almost doubled, whereas there was no increased risk of congenital abnormalities or prematurity in women exposed to a drug overdose compared with the background population." | 1.31 | Pregnancy outcome after suicide attempt by drug use: a Danish population-based study. ( Flint, C; Larsen, H; Nielsen, GL; Olsen, J; Sørensen, HT, 2002) |
| "A therapy-resistant angle closure glaucoma following displacement of the lens-iris diaphragm due to massive choroidal and subretinal hemorrhages has rarely been reported." | 1.30 | [Acute glaucoma caused by massive subretinal hemorrhage in age-related macular degeneration and disordered thrombocyte function]. ( Hesse, L; Poller, S, 1997) |
| "Danish drug abusers have discovered that codeine is easily separated from certain drugs containing acetylsalicylic acid and codeine." | 1.29 | Abuse of codeine separated from over-the-counter drugs containing acetylsalicylic acid and codeine. ( Hansen, AC; Jensen, S, 1993) |
| "confusional migraine with amnesia; and 3." | 1.28 | Organic dissociative syndrome associated with antimigraine pharmacotherapy. ( Good, MI, 1991) |
| "Substance abuse has been reported frequently in chronic headache patients." | 1.28 | Drug abuse and headache. ( Elkind, AH, 1991) |
| " This relationship may represent a dose-response curve relating amount of analgesic intake to prevalence of nephropathy." | 1.27 | Renal disease from habitual antipyretic analgesic consumption: an assessment of the epidemiologic evidence. ( Buckalew, VM; Schey, HM, 1986) |
| " RPN is almost universally reported after long term administration of NSAID to rats, reports being cited for an indomethacin analog, phenylbutazone, fenamic acids, fenoprofen and sudoxicam." | 1.25 | Anti-inflammatory drugs and renal papillary necrosis. ( Reinert, H; Wiseman, EH, 1975) |
| "Phenacetin was removed from this preparation in 1970 and replaced by an approximately equal amount of ASA (ACC)." | 1.25 | Letter: The clinical course of patients with analgesic nephropathy. ( Gault, MH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 136 (77.71) | 18.7374 |
| 1990's | 19 (10.86) | 18.2507 |
| 2000's | 12 (6.86) | 29.6817 |
| 2010's | 8 (4.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Daveluy, A | 1 |
| Géniaux, H | 1 |
| Baumevieille, M | 1 |
| Létinier, L | 1 |
| Matta, MN | 1 |
| Lazès-Charmetant, A | 1 |
| Haramburu, F | 1 |
| Guéroult, P | 1 |
| Abebe, W | 1 |
| Marcucci, M | 1 |
| Lip, GY | 1 |
| Nieuwlaat, R | 1 |
| Pisters, R | 1 |
| Crijns, HJ | 1 |
| Iorio, A | 1 |
| Golden, LE | 1 |
| Sassoon, P | 1 |
| Cáceda, R | 1 |
| Sadeghi, M | 1 |
| Farhoudian, A | 1 |
| Vishteh, HR | 1 |
| Rahimzadeh, S | 1 |
| Fekri, M | 1 |
| Movaghar, AR | 1 |
| Sefatian, S | 1 |
| Raheemullah, A | 1 |
| Laurence, TN | 1 |
| RAWLINGS, KO | 1 |
| Teixeira, OH | 1 |
| Mehta, AV | 1 |
| Garg, P | 1 |
| Davis, G | 1 |
| Wilson, JI | 1 |
| Sivananthan, M | 1 |
| Swarbrick, M | 1 |
| Fitzgerald, C | 1 |
| Martínez, JG | 1 |
| Saus, C | 1 |
| Morey, A | 1 |
| Alarcón, A | 1 |
| Juvela, S | 1 |
| LOZINSKI, E | 1 |
| PLASS, HF | 1 |
| RIVIN, AU | 1 |
| WILSON, CW | 1 |
| Woodside, DB | 1 |
| Colton, P | 1 |
| Staab, R | 1 |
| Schreiber, M | 1 |
| Sutandar-Pinnock, K | 1 |
| Poynter, B | 1 |
| Sacevich, T | 1 |
| Telman, G | 1 |
| Kouperberg, E | 1 |
| Schlesinger, I | 1 |
| Yarnitsky, D | 1 |
| Løgstrup, BB | 1 |
| Øgaard, S | 1 |
| McCreary, C | 1 |
| Colman, A | 1 |
| Vítko, S | 1 |
| Prát, V | 1 |
| Matousovic, K | 1 |
| Dráb, K | 1 |
| Horcicková, M | 1 |
| Hoffmeister, F | 2 |
| Ryser, PE | 1 |
| Maher, JF | 1 |
| Porter, D | 1 |
| Babington, MA | 1 |
| Monson, RA | 1 |
| Eisinger, AJ | 1 |
| Weber, E | 1 |
| Anandan, JV | 1 |
| Matzke, GR | 1 |
| Lanas, AI | 1 |
| Remacha, B | 1 |
| Esteva, F | 1 |
| Sáinz, R | 1 |
| Hasegawa, TK | 1 |
| Matthews, M | 1 |
| Gage, T | 1 |
| Gutnik, SH | 1 |
| Willmott, D | 1 |
| Ziebarth, J | 1 |
| Bättig, K | 1 |
| Jensen, S | 1 |
| Hansen, AC | 1 |
| Van Marter, LJ | 1 |
| Leviton, A | 1 |
| Allred, EN | 1 |
| Pagano, M | 1 |
| Sullivan, KF | 1 |
| Cohen, A | 1 |
| Epstein, MF | 1 |
| Hollander, JE | 1 |
| Kantachuvesiri, S | 1 |
| Kaojarern, S | 1 |
| Kitayaporn, D | 1 |
| Phanichphant, S | 1 |
| Sumethkul, V | 1 |
| Wananukul, W | 1 |
| Pongskul, C | 1 |
| Arkaravichien, W | 1 |
| Jankriengkri, S | 1 |
| Chanchairujira, T | 1 |
| Poller, S | 1 |
| Hesse, L | 1 |
| Aichmüller, C | 1 |
| Schütz, C | 1 |
| Soyka, M | 1 |
| Bray, PF | 1 |
| Bucher, C | 1 |
| Jordan, P | 1 |
| Nickeleit, V | 1 |
| Torhorst, J | 1 |
| Mihatsch, MJ | 1 |
| Hüppe, A | 1 |
| Janke, W | 1 |
| Gould, WS | 1 |
| Malinin, AI | 1 |
| Callahan, KP | 1 |
| Serebruany, VL | 1 |
| Desai, MM | 1 |
| Rosenheck, RA | 1 |
| Druss, BG | 1 |
| Perlin, JB | 1 |
| Flint, C | 1 |
| Larsen, H | 1 |
| Nielsen, GL | 1 |
| Olsen, J | 1 |
| Sørensen, HT | 1 |
| Berkowitz, BA | 1 |
| Miller, RR | 2 |
| Sofia, RD | 1 |
| Diamantis, W | 1 |
| Ludwig, BJ | 1 |
| Coughlin, GP | 1 |
| Willing, RL | 1 |
| Hamilton, DW | 1 |
| Nanra, RS | 3 |
| Stuart-Taylor, J | 1 |
| de Leon, AH | 1 |
| White, KH | 1 |
| Merriman, E | 1 |
| Bell, W | 1 |
| Long, DM | 1 |
| Benowitz, NL | 1 |
| Rosenberg, J | 1 |
| Becker, CE | 1 |
| Laplante, L | 1 |
| Beaudry, C | 1 |
| Kincaid-Smith, P | 4 |
| Dorman, JM | 1 |
| Gault, MH | 6 |
| Wilson, DR | 1 |
| Krupka, LR | 1 |
| Vener, AM | 1 |
| Stewart, CS | 1 |
| Zaenglein-Senger, MM | 1 |
| Wiseman, EH | 1 |
| Reinert, H | 1 |
| Fenner, H | 1 |
| Burns, C | 1 |
| Breife, C | 1 |
| Johansson, R | 1 |
| Sjöberg, C | 1 |
| Christie, D | 1 |
| McPherson, L | 1 |
| Floate, DA | 1 |
| Duggan, JM | 5 |
| Zedler, G | 1 |
| Wigley, RA | 1 |
| Stewart, JH | 1 |
| Gallery, ED | 1 |
| Rittenhouse, M | 1 |
| McFee, AS | 1 |
| Aust, JB | 1 |
| Goldberger, LE | 1 |
| Talner, LB | 1 |
| Murray, T | 2 |
| Goldberg, M | 3 |
| Arger, PH | 1 |
| Bluth, EI | 1 |
| Stevenson, DD | 1 |
| Mathison, DA | 1 |
| Tan, EM | 1 |
| Vaughan, JH | 1 |
| Parker, RW | 1 |
| Shaw, RE | 1 |
| Kramer, P | 1 |
| Glauser, FL | 1 |
| Smith, WR | 1 |
| Adams, FG | 1 |
| Murray, RM | 7 |
| Alexander, GJ | 1 |
| Good, MI | 1 |
| Paterson, JR | 1 |
| Talwar, DK | 1 |
| Watson, ID | 1 |
| Stewart, MJ | 1 |
| Dubach, UC | 2 |
| Rosner, B | 1 |
| Stürmer, T | 1 |
| Hallas, J | 1 |
| Jensen, KB | 1 |
| Grodum, E | 1 |
| Damsbo, N | 1 |
| Gram, LF | 1 |
| Elkind, AH | 1 |
| Sands, GH | 1 |
| Ng, SC | 1 |
| Lee, MK | 1 |
| Teh, A | 1 |
| Devenyi, P | 1 |
| Rideout, J | 1 |
| Schneiderman, J | 1 |
| Strauss, A | 1 |
| Fikr, V | 1 |
| Budka, I | 1 |
| Stika, L | 1 |
| Oyler, JJ | 1 |
| Buckalew, VM | 1 |
| Schey, HM | 1 |
| Jacobsen, CD | 1 |
| Moss, GD | 1 |
| Chmell, S | 1 |
| Pillars, JR | 1 |
| Haid, S | 1 |
| Milewski, S | 1 |
| Fang, YZ | 1 |
| Greene, JG | 1 |
| Adams, JH | 1 |
| Blennerhassett, J | 1 |
| Muehrcke, RC | 1 |
| Blue, JA | 1 |
| Timbury, GC | 1 |
| Linton, AL | 2 |
| Vida, JA | 1 |
| Samour, CM | 1 |
| O'Dea, MH | 1 |
| Wang, TS | 1 |
| Chapman, BL | 2 |
| Johnson, KG | 1 |
| Donnelly, JH | 1 |
| Scheble, R | 1 |
| Wine, RL | 1 |
| Weitman, M | 1 |
| Wainscoat, JS | 1 |
| Finn, R | 1 |
| Richens, A | 1 |
| Bailey, RR | 1 |
| Neale, TJ | 1 |
| Little, PJ | 1 |
| Raaflaub, J | 1 |
| Sutton, E | 1 |
| Soyka, LF | 1 |
| Friedman, AP | 1 |
| Liu, T | 1 |
| Smith, GW | 1 |
| Rankin, JT | 1 |
| Marshall, N | 1 |
| Kuzemko, JA | 1 |
| Rundle, F | 1 |
| Halpern, LM | 1 |
| Horváth, Z | 1 |
| MacDonald, WC | 1 |
| Naess, K | 1 |
| Kullberg, MP | 1 |
| Gorodetzky, CW | 1 |
| Heggarty, H | 1 |
| Levin, NW | 1 |
| Brazelton, TB | 1 |
| Feingold, A | 1 |
| Paxinos, J | 1 |
| Vandam, LD | 1 |
| Gillies, MA | 1 |
| Skyring, AP | 1 |
| Peter, ME | 1 |
| Benfield, JR | 1 |
| Hyde, JS | 1 |
| Floro, LD | 1 |
| Vithayasai, V | 1 |
| Brown, CB | 1 |
| McMillan, JM | 2 |
| Bateman, CJ | 1 |
| Cattell, WR | 1 |
| Done, AK | 1 |
| Ferris, GN | 1 |
| Kiplinger, GF | 1 |
| Nickander, R | 1 |
| Costello, JM | 1 |
| Shannon, FT | 1 |
| Savage, PP | 1 |
| Rudwal, TC | 2 |
| Redmond, NI | 1 |
| Hansky, J | 1 |
| Allmand, F | 1 |
| O'Brien, JR | 1 |
| Wenger, J | 1 |
| Einstein, S | 1 |
| Adam, WR | 1 |
| Dawborn, JK | 1 |
| Price, CG | 1 |
| Riddell, J | 1 |
| Story, H | 1 |
| Morgan, LK | 1 |
| Surapathana, LO | 1 |
| Futrakul, P | 1 |
| Campbell, RA | 1 |
| Christensen, JK | 1 |
| Fischer, PA | 1 |
| Jorgensen, TG | 1 |
| Strandbygaard, N | 1 |
| Emblem, L | 1 |
| Paliard, P | 1 |
| Moulinier, B | 1 |
| Eyraud, J | 1 |
| Bruhiere, J | 1 |
| Vedrinne, J | 1 |
| Vondrácek, V | 1 |
| Prokupek, J | 1 |
| Fischer, R | 1 |
| Ahrenbergová, M | 1 |
| Engles, WD | 1 |
| Dossetor, JB | 1 |
| Boyd, EM | 1 |
| Sours, JA | 1 |
| Gillies, M | 1 |
| Skyring, A | 1 |
| Lawson, DH | 1 |
| Paton, AM | 1 |
| Prescott, LF | 1 |
| Bluemle, LW | 1 |
| de Vries, SI | 1 |
| ten Cate, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)[NCT02409680] | 11,976 participants (Actual) | Interventional | 2016-03-23 | Completed | |||
| Comparison Study of a Low-Fat Diet Supplemented With Fish Oil and a Standard Western Diet in Individuals With Prostate Cancer[NCT00798876] | 56 participants (Actual) | Interventional | 2001-12-18 | Completed | |||
| E-CRANIO Trial Study on Elective CRAniotomies: Postoperative Neurointensive Care, Imaging and Outcome[NCT01987648] | 1,969 participants (Actual) | Observational | 2011-11-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
- Early preterm delivery (<34 weeks) (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 189 |
| Placebo Arm | 230 |
- Birth weight <2500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1078 |
| Placebo Arm | 1153 |
- Birth weight <1500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 78 |
| Placebo Arm | 101 |
- Incidence of Fetal Loss (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 303 |
| Placebo Arm | 353 |
- Incidence of Spontaneous Abortion (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 134 |
| Placebo Arm | 152 |
- Incidence of All stillbirth (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 141 |
| Placebo Arm | 166 |
- Incidence of Medical Termination of Pregnancy (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 42 |
| Placebo Arm | 30 |
- Hypertensive disorders of pregnancy is defined by the characterization of evidence of a hypertensive disorder, including either preeclampsia or eclampsia occurring during the pregnancy. (NCT02409680)
Timeframe: Evidence of hypertensive disorder during the pregnancy (prior to delivery/birth)
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 352 |
| Placebo Arm | 325 |
- Incidence of Perinatal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 264 |
| Placebo Arm | 309 |
The primary outcome of this study is incidence of preterm birth, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks. This will be determined based on actual date of delivery in comparison to the projected estimated due date (EDD), independent of whether or not the preterm delivery is indicated or spontaneous. (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 668 |
| Placebo Arm | 754 |
- Small for gestational age (SGA) as defined by the INTERGROWTH-21st standard (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1506 |
| Placebo Arm | 1564 |
- Vaginal bleeding (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 214 |
| Placebo Arm | 246 |
- Antepartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 26 |
| Placebo Arm | 25 |
- Postpartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 54 |
| Placebo Arm | 43 |
- Incidence of Maternal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 9 |
| Placebo Arm | 12 |
- Incidence of Late Abortion (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 23 |
| Placebo Arm | 30 |
Hemoglobin < 7.0 gm/dl at 26-30 weeks gestation or a drop of 3.5+ gm/dl from screening to 26-30 weeks gestation (NCT02409680)
Timeframe: At enrollment, 4 weeks post enrollment, and 26-30 weeks GA.
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 290 |
| Placebo Arm | 333 |
Early preterm delivery (<34 weeks) and hypertensive disorders (i.e.: preeclampsia) (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 8 |
| Placebo Arm | 21 |
16 reviews available for aspirin and Chemical Dependence
| Article | Year |
|---|---|
Khat: A Substance of Growing Abuse with Adverse Drug Interaction Risks.
Topics: Anesthetics; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antihypertensive Agents; Aspirin; Catha; | 2018 |
Acute and chronic cardiovascular and behavioural effects of caffeine, aspirin and ephedrine.
Topics: Aspirin; Behavior; Caffeine; Drug Interactions; Ephedrine; Hemodynamics; Humans; Substance-Related D | 1993 |
Cocaine-associated myocardial infarction.
Topics: Adult; Aged; Aspirin; Benzodiazepines; Cocaine; Humans; Middle Aged; Myocardial Infarction; Myocardi | 1996 |
The relationship of pharmacokinetics to pharmacological activity: morphine, methadone and naloxone.
Topics: Absorption; Aging; Aspirin; Blood Proteins; Dose-Response Relationship, Drug; Drug Interactions; Fem | 1976 |
Propoxyphene: a review.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Chemical Phenomena; Chemistry; Dextropropoxyphene; Dru | 1977 |
Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia.
Topics: Adult; Age Factors; Aged; Analgesics; Animals; Aspirin; Australia; Caffeine; Drug Combinations; Fema | 1978 |
Analgesic abuse syndrome: a frequently overlooked cause of reversible renal failure.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Diagnosis, Differential; Dr | 1975 |
Analgesic abuse and renal disease.
Topics: Acetaminophen; Adult; Aged; Animals; Aspirin; Creatinine; Drug Combinations; Humans; Inactivation, M | 1975 |
Analgesic abuse nephropathy.
Topics: Analgesics; Aspirin; Calcinosis; Female; Humans; Kidney Failure, Chronic; Kidney Papillary Necrosis; | 1976 |
[Pathogenesis of chronic interstitial nephritis following prolonged analgesic abuse].
Topics: Analgesics; Aniline Compounds; Animals; Aspirin; Chronic Disease; Dogs; Drug Hypersensitivity; Ethyl | 1972 |
Unravelling analgesic nephropathy.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Carcinoma, Transitional Cell; Female; Humans; Kidney Ne | 1972 |
Chronic effect of analgesics on the kidney.
Topics: Aminopyrine; Analgesics; Animals; Antipyrine; Aspirin; Caffeine; Chronic Disease; Drug Combinations; | 1972 |
How safe is acetaminophen? Some practical cautions with this widely used agent.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Chemical Phenomena; Chemistry; Child; Drug Synergism; F | 1973 |
Analgesic nephrotoxicity.
Topics: Analgesics; Aspirin; Caffeine; Female; Humans; Male; Nephritis; Phenacetin; Substance-Related Disord | 1969 |
Effect of prenatal drugs on the behavior of the neonate.
Topics: Aspirin; Barbiturates; Behavior; Body Weight; Depression, Chemical; Diet; Female; Fetus; Genotype; G | 1970 |
Propoxyphene hydrochloride. A critical review.
Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Female; Headac | 1970 |
4 trials available for aspirin and Chemical Dependence
| Article | Year |
|---|---|
[Experimental study of the effect of acetylsalicylic acid combined with caffeine regarding possible abuse potential].
Topics: Adult; Affect; Arousal; Aspirin; Caffeine; Dose-Response Relationship, Drug; Double-Blind Method; Dr | 2001 |
Paradoxical activation of major platelet receptors in the methadone-maintained patients after single pill of aspirin.
Topics: Adult; Aspirin; Coronary Artery Disease; Drug Interactions; Female; Humans; Male; Methadone; Middle | 2001 |
Darvon and Darvon-N.
Topics: Administration, Oral; Adolescent; Aspirin; Brain; Clinical Trials as Topic; Cognition Disorders; Cos | 1972 |
Propoxyphene hydrochloride. A critical review.
Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Female; Headac | 1970 |
156 other studies available for aspirin and Chemical Dependence
| Article | Year |
|---|---|
Parachuting psychoactive substances: Pharmacokinetic clues for harm reduction.
Topics: Administration, Oral; Aspirin; Delayed-Action Preparations; Drug Overdose; Gastrointestinal Transit; | 2018 |
Stroke and bleeding risk co-distribution in real-world patients with atrial fibrillation: the Euro Heart Survey.
Topics: Age Distribution; Aged; Alcohol Drinking; Anticoagulants; Aspirin; Atrial Fibrillation; Diabetes Com | 2014 |
A case report of late onset psychosis with dementia and aspirin and caffeine addiction.
Topics: Age of Onset; Aspirin; Caffeine; Central Nervous System Agents; Dementia; Diagnosis, Differential; H | 2015 |
A tentative component analysis of Norjizak: A new abused drug in Iran.
Topics: Aspirin; Betamethasone; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; | 2015 |
Repeated Thrombosis After Synthetic Cannabinoid Use.
Topics: Adult; Anticoagulants; Aspirin; Cannabinoids; Enoxaparin; Female; Humans; Infarction; Platelet Aggre | 2016 |
The use and abuse of aspirin.
Topics: Aspirin; Humans; Mental Disorders; Substance-Related Disorders | 1948 |
Aortic thrombosis in infancy.
Topics: Anticoagulants; Aortic Diseases; Aspirin; Echocardiography, Doppler; Enoxaparin; Female; Humans; Inf | 2009 |
Intravascular ultrasound and angiographic demonstration of left main stem thrombus-high-risk presentation in a young adult with anabolic steroid abuse.
Topics: Abciximab; Anabolic Agents; Antibodies, Monoclonal; Aspirin; Clopidogrel; Coronary Angiography; Coro | 2010 |
The Million Hearts™ initiative: why psychosocial nurses should care.
Topics: Aspirin; Cholesterol; Comorbidity; Health Promotion; Humans; Hypertension; Mental Disorders; Myocard | 2012 |
[Crohn's disease and renal amyloidosis. Acute renal failure].
Topics: Acetaminophen; Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Amyloidosis; Analgesics, Non-Nar | 2002 |
Nonsteroidal anti-inflammatory drugs as risk factors for spontaneous intracerebral hemorrhage and aneurysmal subarachnoid hemorrhage.
Topics: Age Factors; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bias; Case-Control | 2003 |
THE COMPARATIVE PHARMACOLOGY.
Topics: Acetaminophen; Acetanilides; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Blood Coag | 1963 |
RENAL PAPILLARY NECROSIS ASSOCIATED WITH ANALGESIC ABUSE.
Topics: Analgesics; Aspirin; Caffeine; Duodenal Ulcer; Humans; Kidney Papillary Necrosis; Phenacetin; Radiog | 1964 |
FALSE ENDOCRINE TEST RESULTS DUE TO DRUGS.
Topics: 17-Ketosteroids; Aspirin; Diagnosis, Differential; Hypnotics and Sedatives; Hypopituitarism; Hypothy | 1964 |
DRUG ADDICTION. PHARMACOLOGICAL ASPECTS OF ADDICTION TO MORPHINE AND OTHER DRUGS.
Topics: Amphetamine; Amphetamines; Aspirin; Behavior, Addictive; Drug Therapy; Hypnotics and Sedatives; Morp | 1965 |
Weight restoration in a patient with anorexia nervosa on dialysis.
Topics: Adult; Anorexia Nervosa; Aspirin; Barbiturates; Body Mass Index; Body Weight; Caffeine; Combined Mod | 2005 |
Cessation of microemboli in the middle cerebral artery after a single dose of aspirin in a young patient with emboliogenic lacunar syndrome of carotid origin.
Topics: Adult; Anemia, Iron-Deficiency; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Brain Infar | 2006 |
[Hypokalaemia as a result of abuse of Kodimagnyl].
Topics: Adult; Analgesics, Opioid; Aspirin; Codeine; Drug Combinations; Drug Overdose; Female; Humans; Hypok | 2007 |
Medication usage, emotional disturbance, and pain behavior in chronic low back pain patients.
Topics: Adult; Affective Symptoms; Analgesics; Analgesics, Opioid; Aspirin; Back Pain; Drug Therapy, Combina | 1984 |
[Analgesic nephropathy. II. Analgesic nephropathy and analgesic syndrome, diagnosis and treatment].
Topics: Adult; Aspirin; Female; Humans; Kidney Diseases; Male; Middle Aged; Phenacetin; Substance-Related Di | 1984 |
[Potential for dependence of analgesics and psychopharmaceuticals].
Topics: Analgesics; Animals; Aspirin; Barbiturates; Conditioning, Operant; Electric Stimulation; Humans; Mor | 1984 |
Students and drug abuse, 1974 and 1980.
Topics: Adolescent; Alcoholism; Aspirin; Child; Diazepam; Humans; Marijuana Abuse; Methaqualone; Students; S | 1983 |
Analgesic nephropathy. Observations, interpretations, and perspective on the low incidence in America.
Topics: Analgesics; Aspirin; Australia; Belgium; Dose-Response Relationship, Drug; Humans; Kidney Papillary | 1984 |
Drug induced confusional state.
Topics: Aged; Amitriptyline; Aspirin; Cognition Disorders; Confusion; Drug Interactions; Female; Humans; Sub | 1982 |
Analgesic abuse and the kidney.
Topics: Aged; Analgesics; Aspirin; Caffeine; Codeine; Drug Combinations; Humans; Kidney; Kidney Diseases; Ki | 1980 |
Dependence on Midol.
Topics: Adult; Aspirin; Caffeine; Drug Combinations; Ephedrine; Female; Humans; Phenacetin; Substance-Relate | 1982 |
Analgesic nephropathy.
Topics: Adult; Analgesics; Aspirin; Female; Humans; Kidney Diseases; Kidney Neoplasms; Male; Middle Aged; Ph | 1981 |
[Surgery-related adverse effects drugs: analgesics].
Topics: Analgesics; Aspirin; Blood Coagulation; Humans; Intestines; Liver; Muscle, Smooth; Narcotics; Phenac | 1981 |
Nephropathy as a hazard of analgesic abuse.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Aspirin; Female; Humans; Kidney Diseases; Male; M | 1981 |
Risk factors associated with refractory peptic ulcers.
Topics: Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Female; Gastric | 1995 |
What would you do? "The pain is really bad and I need something (Percodan) now.".
Topics: Acute Disease; Analgesics, Opioid; Aspirin; Caffeine; Drug Combinations; Ethics, Dental; Facial Pain | 1994 |
Gastrocolic fistula-secondary to aspirin abuse.
Topics: Aspirin; Colonic Diseases; Female; Gastric Fistula; Humans; Intestinal Fistula; Middle Aged; Stomach | 1993 |
Abuse of codeine separated from over-the-counter drugs containing acetylsalicylic acid and codeine.
Topics: Aspirin; Codeine; Denmark; Drug Combinations; Humans; Nonprescription Drugs; Substance Abuse Detecti | 1993 |
Persistent pulmonary hypertension of the newborn and smoking and aspirin and nonsteroidal antiinflammatory drug consumption during pregnancy.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Cocaine; Confounding | 1996 |
Risk factors between analgesic use and chronic nephropathy in Thailand.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ca | 1996 |
[Acute glaucoma caused by massive subretinal hemorrhage in age-related macular degeneration and disordered thrombocyte function].
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Eye Enucleation; Female; Glau | 1997 |
[Abuse of and dependence on mixed analgesics--clinical aspects and differential diagnostic problems].
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Diagnosis, Differential; Drug Combinations; Hum | 1998 |
Are we still abusing aspirin?
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Humans; Multiple Organ Failure; Plate | 1998 |
Relative risk of malignant tumors in analgesic abusers. Effects of long-term intake of aspirin.
Topics: Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Male; Neoplasms; | 1999 |
Drugs for pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2000 |
"No, Duke. No divorce".
Topics: Aspirin; Caffeine; Deception; Drug Combinations; Drug Prescriptions; Humans; Male; Middle Aged; Oxyc | 2001 |
Mental disorders and quality of care among postacute myocardial infarction outpatients.
Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Ambulatory Care; Anticholesteremic Agents; Aspirin | 2002 |
Pregnancy outcome after suicide attempt by drug use: a Danish population-based study.
Topics: Abortion, Spontaneous; Acetaminophen; Adolescent; Adult; Aspirin; Child; Child, Preschool; Denmark; | 2002 |
Pharmacological properties of 2,3-dihydro-9H-isoxazolo [3,2-b] quinazolin-9-one (W-2429. Part 1: Analgesic, antipyretic and antiedema activity.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthriti | 1977 |
Gastro-colic fistula complicating benign gastric ulcer in analgesic abusers.
Topics: Adult; Aspirin; Colonic Diseases; Female; Gastric Fistula; Humans; Intestinal Fistula; Stomach Ulcer | 1979 |
Self-administration of codeine plus acetylsalicylic acid in rhesus monkeys with unlimited access to the drugs.
Topics: Animals; Aspirin; Codeine; Drug Synergism; Haplorhini; Humans; Macaca mulatta; Substance-Related Dis | 1977 |
Surgical postoperative bleeding associated with aspirin ingestion. Report of two cases.
Topics: Aged; Aspirin; Blood Platelet Disorders; Hematoma; Humans; Male; Middle Aged; Neurosurgery; Postoper | 1979 |
Cardiopulmonary catastrophes in drug-overdosed patients.
Topics: Adolescent; Adult; Amphetamines; Antidepressive Agents; Arrhythmias, Cardiac; Aspirin; Cardiovascula | 1979 |
[Severe acetylsalicylic acid poisoning: epidemiologic data. 10-year study].
Topics: Acute Disease; Adolescent; Adult; Aspirin; Child; Child, Preschool; Chronic Disease; Epidemiologic M | 1979 |
Analgesic nephropathy in Australia.
Topics: Adolescent; Adult; Age Factors; Aged; Analgesics; Aspirin; Australia; Child; Climate; Female; Geogra | 1979 |
University infirmary admissions for drug abuse, 1968--1970 and 1973--1975.
Topics: Adult; Aspirin; Cannabis; Diazepam; Female; Hallucinogens; Humans; Male; Patient Admission; Student | 1979 |
Analgesic nephropathy in Canada: clinical syndrome, management, and outcome.
Topics: Adult; Aged; Analgesics; Aspirin; Caffeine; Canada; Codeine; Creatinine; Drug Combinations; Female; | 1978 |
Patterns of aspirin use among American youth.
Topics: Adolescent; Adult; Age Factors; Aspirin; Child; Female; Health Education; Humans; Male; Self Disclos | 1978 |
Anti-inflammatory drugs and renal papillary necrosis.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Drug Combinations; Female; Haplorhini; | 1975 |
[The problems of the various characteristics of drug abuse (author's transl)].
Topics: Alcoholism; Analgesics; Animals; Aspirin; Humans; Hypnotics and Sedatives; Nonprescription Drugs; Pr | 1976 |
Phensic addiction.
Topics: Adult; Aspirin; Caffeine; Drug Combinations; Female; Humans; Kidney Diseases; Salicylamides; Substan | 1977 |
[Abuse of codeine cakes or of drug combinations with codeine-acetylsalicylic acid].
Topics: Adult; Aspirin; Codeine; Drug Combinations; Female; Humans; Male; Middle Aged; Nonprescription Drugs | 1976 |
Analgesics and the kidney: a community-based study.
Topics: Adult; Analgesics; Aspirin; Australia; Female; Humans; Kidney Diseases; Leukocytes; Male; Middle Age | 1976 |
Hour-glass stomach: an explanation.
Topics: Adult; Aged; Aspirin; Constriction, Pathologic; Female; Humans; Male; Middle Aged; Sex Factors; Stom | 1976 |
[Indications and contraindications for analgesics in certain organic diseases and dispositions].
Topics: Analgesics; Aspirin; Drug Hypersensitivity; Humans; Intraocular Pressure; Kidney; Laryngeal Edema; P | 1976 |
The New Zealand experience.
Topics: Aspirin; Drug Combinations; Drug Synergism; Humans; Kidney Papillary Necrosis; New Zealand; Phenacet | 1976 |
Analgesic abuse and kidney disease.
Topics: Analgesics; Animals; Aspirin; Australia; Carcinoma, Transitional Cell; Female; Humans; Kidney Diseas | 1976 |
Gastric devascularization: an alternate approach to the surgical treatment of massive, diffuse hemorrhage from gastritis.
Topics: Adult; Age Factors; Alcoholism; Aspirin; Burns; Child, Preschool; Female; Gastrectomy; Gastritis; Ga | 1976 |
Analgesic nephropathy.
Topics: Acetaminophen; Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Co | 1976 |
Letter: Possible role of laxatives in analgesic nephropathy.
Topics: Analgesics; Aspirin; Cathartics; Codeine; Female; Humans; Kidney Diseases; Male; Phenacetin; Substan | 1975 |
Editorial: Analgesic nephropathy: some unsolved problems.
Topics: Analgesics; Animals; Aspirin; Humans; Kidney Diseases; Kidney Papillary Necrosis; Phenacetin; Rats; | 1975 |
Provoking factors in bronchial asthma.
Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Bronchitis; Child; Child, Preschool; Drug Hypersensitivity | 1975 |
Analgesic abuse in urological practice.
Topics: Acute Kidney Injury; Adult; Aged; Anemia; Aspirin; Codeine; Female; Humans; Hypertension; Kidney Cal | 1975 |
[Analgesic nephropathy].
Topics: Acidosis, Renal Tubular; Analgesics; Aspirin; Autopsy; Caffeine; Creatinine; Drug Interactions; Fema | 1975 |
Letter: The clinical course of patients with analgesic nephropathy.
Topics: Analgesics; Aspirin; Caffeine; Codeine; Creatinine; Female; Follow-Up Studies; Humans; Kidney; Kidne | 1975 |
Physiologic and biochemical abnormalities in self-induced drug overdosage.
Topics: Adolescent; Adult; Aged; Aspirin; Barbiturates; Body Temperature; Carbamates; Creatine Kinase; Diaze | 1975 |
The radiological diagnosis of analgesic nephropathy.
Topics: Adult; Aged; Aspirin; Atrophy; Calcinosis; Creatinine; Female; Humans; Hydronephrosis; Kidney; Kidne | 1975 |
Editorial: Aspirin and chronic gastric ulcer.
Topics: Adult; Aspirin; Australia; Chronic Disease; Female; Humans; Middle Aged; Stomach Ulcer; Substance-Re | 1976 |
Direct use of ion-exchange papers in hemagglutination-inhibition tests for drug abuse.
Topics: Aspirin; Chlorpromazine; Chromatography, Ion Exchange; Chromatography, Paper; Codeine; Hemagglutinat | 1976 |
"I'm a chemically dependent dentist"/Case 3. An inherited problem.
Topics: Adult; Aspirin; Caffeine; Codeine; Dentists; Drug Combinations; Humans; Oxycodone; Phenacetin; Physi | 1990 |
Organic dissociative syndrome associated with antimigraine pharmacotherapy.
Topics: Adolescent; Analgesics; Aspirin; Barbiturates; Caffeine; Dissociative Disorders; Drug Combinations; | 1991 |
Codeine abuse from co-codaprin.
Topics: Aspirin; Codeine; Drug Combinations; Humans; Substance-Related Disorders | 1990 |
An epidemiologic study of abuse of analgesic drugs. Effects of phenacetin and salicylate on mortality and cardiovascular morbidity (1968 to 1987)
Topics: Adult; Aged; Aspirin; Cardiovascular Diseases; Dose-Response Relationship, Drug; Female; Humans; Hyp | 1991 |
Drug-related admissions to a department of medical gastroenterology. The role of self-medicated and prescribed drugs.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Denmark; Female; G | 1991 |
Drug abuse and headache.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Ergot Alkaloi | 1991 |
A protocol for butalbital, aspirin and caffeine (BAC) detoxification in headache patients.
Topics: Adult; Aspirin; Barbiturates; Caffeine; Clinical Protocols; Combined Modality Therapy; Female; Heada | 1990 |
Acute organic brain syndrome due to drug-induced eosinophilia.
Topics: Acetaminophen; Aged; Anti-Bacterial Agents; Aspirin; Drugs, Chinese Herbal; Eosinophilia; Humans; Ma | 1989 |
Abuse of a commonly prescribed analgesic preparation.
Topics: Adult; Analgesics, Opioid; Aspirin; Barbiturates; Caffeine; Codeine; Drug Combinations; Female; Huma | 1985 |
Homicidal psychosis during the combined use of cocaine and an over-the-counter cold preparation.
Topics: Adult; Aspirin; Bicarbonates; Chlorpheniramine; Citrates; Cocaine; Drug Combinations; Homicide; Huma | 1989 |
[Possibilities of modelling of an undesirable phenomenon-- non-alcoholic substance abuse in society].
Topics: Adolescent; Adult; Alcohol Drinking; Aspirin; Caffeine; Child; Codeine; Czechoslovakia; Drug Combina | 1988 |
Drugs and alcohol--a dentist's story of addiction.
Topics: Alcoholism; Aspirin; Caffeine; Dentists; Dextropropoxyphene; Drug Combinations; Humans; Male; Oxycod | 1986 |
Renal disease from habitual antipyretic analgesic consumption: an assessment of the epidemiologic evidence.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Kidney; Kidney Diseases; Kidney Failure, C | 1986 |
[Acetylsalicylic acid].
Topics: Aged; Aspirin; Humans; Male; Melena; Substance-Related Disorders | 1986 |
Femoral artery laceration complicating an intertrochanteric hip fracture: a multi-disciplinary therapeutic problem.
Topics: Aged; Aspirin; Embolization, Therapeutic; Female; Femoral Artery; Hematoma; Hip Fractures; Humans; O | 1985 |
[Antipyretic and analgesic dependence in two villages].
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coffee; Female; Humans; Male; M | 1985 |
Analgesics abuse and dementia.
Topics: Aged; Analgesics; Aspirin; Brain; Dementia; Female; Humans; Intelligence Tests; Male; Middle Aged; P | 1971 |
Analgesic nephropathy. A clinicopathologic study using electron microscopy.
Topics: Adult; Aspirin; Autopsy; Bacterial Infections; Basement Membrane; Beta-Globulins; Biopsy; Collagen; | 1971 |
Aspirin and the blood.
Topics: Anemia, Aplastic; Aspirin; Gastric Mucosa; Hematemesis; Hemophilia A; Humans; Substance-Related Diso | 1966 |
Rhinitis medicamentosa.
Topics: Aspirin; Cocaine; Drug Hypersensitivity; Ephedrine; Epinephrine; Estrogens; Humans; Iodides; Ipecac; | 1968 |
Analgesic abuse in psychiatric patients.
Topics: Adult; Aged; Anemia; Aspirin; Creatinine; Dyspepsia; Female; Humans; Kidney Diseases; Male; Mental D | 1970 |
Analgesics. 2. Selected 5-substituted 5-(1-phenylethyl)barbituric acids.
Topics: Administration, Oral; Aminopyrine; Analgesics; Animals; Aspirin; Barbiturates; Central Nervous Syste | 1974 |
Environmental factors and the Australian gastric ulcer change.
Topics: Adrenal Cortex Hormones; Adult; Alcohol Drinking; Aspirin; Australia; Disabled Persons; Duodenal Ulc | 1969 |
Survey of adolescent drug use. I. Sex and grade distribution.
Topics: Adolescent; Age Factors; Alcohol Drinking; Amphetamine; Aspirin; Barbiturates; Cannabis; Cocaine; De | 1971 |
Possible role of laxatives in analgesic nephropathy.
Topics: Adult; Aged; Analgesics; Arthritis, Rheumatoid; Aspirin; Cathartics; Codeine; Creatinine; Drug Combi | 1974 |
Developments in drug therapy.
Topics: Antiparkinson Agents; Appetite Depressants; Aspirin; Biopharmaceutics; Drug-Related Side Effects and | 1973 |
Dependance on analgesics in analgesic nephropathy.
Topics: Adult; Aged; Analgesics; Aspirin; Caffeine; Chemical and Drug Induced Liver Injury; Codeine; Female; | 1973 |
Analgesic nephropathy and aspirin.
Topics: Analgesics; Aspirin; Female; Humans; Kidney Diseases; Male; Phenacetin; Substance-Related Disorders | 1974 |
Analgesic nephropathy.
Topics: Adult; Aged; Analgesics; Anemia; Aspirin; Codeine; Drug Combinations; Female; Follow-Up Studies; Hum | 1974 |
Reflections on the treatment of headache.
Topics: Animals; Aspirin; Cyproheptadine; Ergotamine; Haplorhini; Headache; Hormones; Humans; Methysergide; | 1972 |
Evidence for the nephrotoxicity of analgesics.
Topics: Analgesics; Aspirin; Caffeine; Humans; Kidney Failure, Chronic; Phenacetin; Pyelonephritis; Substanc | 1972 |
Renal pelvic tumour associated with analgesic abuse.
Topics: Adenocarcinoma; Aged; Alcoholism; Analgesics; Aspirin; Caffeine; Codeine; Drug Synergism; Female; Hu | 1972 |
The use and abuse of analgesics.
Topics: Analgesics; Aspirin; Female; Humans; Kidney Diseases; Male; Mental Disorders; Scotland; Self Medicat | 1972 |
Aspirin and haematemesis in children.
Topics: Aspirin; Child; Child, Preschool; Female; Hematemesis; Humans; Male; Medical History Taking; Substan | 1972 |
Percodan.
Topics: Analgesics; Aspirin; Caffeine; Codeine; Drug Combinations; Humans; Morphinans; Narcotics; Phenacetin | 1972 |
The dilemma of a prison doctor.
Topics: Anesthesia; Arthritis; Aspirin; Behavior Therapy; Delivery of Health Care; Fluphenazine; Hostility; | 1972 |
Analgesics and other drugs for relief of pain.
Topics: Analgesics; Aspirin; Azepines; Carbamazepine; Codeine; Dextropropoxyphene; Humans; Indomethacin; Met | 1973 |
[Studies on the causes for drug abuse using ethylmorphine hydrochloride and acetylsalicylic-acid-containing drug combinations].
Topics: Aspirin; Drug Combinations; Drug Synergism; Humans; Morphinans; Morphine Dependence; Substance-Relat | 1973 |
Correlation of mucosal histology and aspirin intake in chronic gastric ulcer.
Topics: Adult; Aged; Aspirin; Caffeine; Chronic Disease; Epithelium; Female; Gastric Mucosa; Gastritis; Huma | 1973 |
The origins of analgesic nephropathy.
Topics: Adult; Affective Symptoms; Aged; Alcoholism; Analgesics; Antipyrine; Aspirin; Codeine; Creatinine; F | 1973 |
[Risks in long-term treatment with analgesics].
Topics: Acetaminophen; Analgesics; Antipyrine; Aspirin; Caffeine; Diuresis; Drug Combinations; Humans; Kidne | 1973 |
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chr | 1974 |
Aspirin and anaemia in childhood.
Topics: Adolescent; Anemia; Aspirin; Child; Child, Preschool; Female; Hemoglobins; Humans; Infant; Iron; Mal | 1974 |
Editorial: Analgesic nephropathy or phenacetin poisoning.
Topics: Animals; Aspirin; Humans; Kidney Failure, Chronic; Phenacetin; Proteinuria; Rats; Substance-Related | 1974 |
Editorial: Choice of a mild analgesic.
Topics: Acetaminophen; Aspirin; Drug Combinations; Humans; Kidney Diseases; Phenacetin; Substance-Related Di | 1974 |
Letter: Aspirin and what else?
Topics: Aspirin; Blood Coagulation; Blood Donors; Blood Platelet Disorders; Blood Transfusion; Humans; Plate | 1974 |
Analgetic drugs--the mild analgetics.
Topics: Acetaminophen; Acetanilides; Administration, Oral; Analgesics; Aspirin; Codeine; Dextropropoxyphene; | 1972 |
The pattern and prevalence of aspirin ingestion as determined by interview of 2,921 inhabitants of Sydney.
Topics: Adult; Age Factors; Aged; Aspirin; Australia; Drug Combinations; Female; Humans; Male; Middle Aged; | 1972 |
Benign gastroenteric fistula and aspirin abuse.
Topics: Aspirin; Female; Gastric Fistula; Gastroenterostomy; Humans; Intestinal Fistula; Jejunum; Middle Age | 1972 |
Chronic and high risk asthma in children.
Topics: Adolescent; Adrenal Cortex Hormones; Aerosols; Airway Obstruction; Aspergillosis; Aspirin; Asthma; B | 1972 |
Acute renal failure following analgesic overdose in G6PD deficiency.
Topics: Acute Disease; Acute Kidney Injury; Adult; Anemia, Hemolytic; Anemia, Sideroblastic; Aspirin; Biopsy | 1972 |
Antipyretics.
Topics: Acetaminophen; Analgesics; Aspirin; Child; Health Education; Humans; Indomethacin; Mefenamic Acid; P | 1972 |
Addiction to Daprisal.
Topics: Adult; Amobarbital; Aspirin; Depression; Dextroamphetamine; Drug Combinations; Female; Humans; Male; | 1972 |
Aspirin ingestion and perforated peptic ulcer.
Topics: Aspirin; Duodenal Ulcer; Female; Humans; Male; Peptic Ulcer Perforation; Sex Factors; Stomach Ulcer; | 1972 |
Analgesic nephropathy: removal of phenacetin from proprietary analgesics.
Topics: Analgesics; Aspirin; Caffeine; Codeine; Drug Combinations; Humans; Kidney Diseases; Phenacetin; Scot | 1972 |
Pharmacologic basis for use of propoxyphene.
Topics: Animals; Aspirin; Bradykinin; Central Nervous System; Codeine; Dextropropoxyphene; Drug Synergism; H | 1971 |
Drugs and children.
Topics: Aminophylline; Aspirin; Atropine; Cardiomyopathies; Cataract; Child, Preschool; Chloramphenicol; Chl | 1968 |
Abuse and addiction--man or drug?
Topics: Adolescent; Adult; Aspirin; Female; Humans; Male; Personality Disorders; Substance-Related Disorders | 1971 |
Analgesic habits of 500 veterans: incidence and complications of abuse.
Topics: Adult; Aged; Analgesics; Anemia; Arthritis; Aspirin; Caffeine; Canada; Codeine; Gastrointestinal Hem | 1968 |
Gastrointestinal haemorrhage gastric ulcer, and aspirin abuse.
Topics: Adult; Age Factors; Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; P | 1969 |
Gastro-intestinal bleeding: the role of vitamin C.
Topics: Ascorbic Acid Deficiency; Aspirin; Feeding Behavior; Gastrointestinal Hemorrhage; Hernia, Diaphragma | 1969 |
Susceptibility to aspirin bleeding.
Topics: Aspirin; Female; Gastrointestinal Hemorrhage; Humans; Male; Substance-Related Disorders | 1970 |
The use and misuse of aspirin: a contemporary problem.
Topics: Adult; Aged; Analgesics; Anemia, Hypochromic; Aspirin; Blood Coagulation; Blood Platelet Disorders; | 1970 |
Analgesic nephropathy. A common form of renal disease in Australia.
Topics: Acetaminophen; Analgesics; Anemia; Animals; Aspirin; Australia; Caffeine; Diagnosis, Differential; D | 1969 |
The incidence of aspirin ingestion in patients with peptic ulcer.
Topics: Adolescent; Adult; Age Factors; Aged; Aspirin; Australia; Caffeine; Child; Duodenal Ulcer; Female; H | 1970 |
Anaplastic transitional-cell carcinoma of the renal pelvis in association with analgesic abuse.
Topics: Adult; Anuria; Aspirin; Autopsy; Blood Chemical Analysis; Caffeine; Carcinoma, Transitional Cell; Fe | 1970 |
The epidemiology of drug overdosage.
Topics: Amphetamine; Aspirin; Caffeine; Dextroamphetamine; Drug and Narcotic Control; Female; Humans; Substa | 1970 |
Salicylism revisited. Unusual problems in diagnosis and management.
Topics: Acidosis, Respiratory; Adolescent; Adult; Alkalosis; Aspirin; Central Nervous System; Colic; Diuresi | 1970 |
[Psychiatric and gastroenterological evaluation of patients with duodenal ulcer confirmed at operation. 100 patients studied by preoperative psychiatric interview and enlarged histamine test with special reference to the relation between psychic factors a
Topics: Adolescent; Adult; Age Factors; Aged; Alcohol Drinking; Aspirin; Character; Child; Drinking Behavior | 1970 |
[Use and misuse of light analgetics for headache].
Topics: Acetaminophen; Antipyrine; Aspirin; Dextropropoxyphene; Headache; Humans; Phenacetin; Salicylamides; | 1971 |
[Stenosing esophagitis, postbulbar duodenal ulcer and aspirin addiction].
Topics: Adult; Aspirin; Duodenal Ulcer; Esophageal Stenosis; Humans; Male; Substance-Related Disorders | 1971 |
Recent patterns of addiction in Czechoslovakia.
Topics: Adult; Analgesics; Antipyrine; Aspirin; Barbiturates; Bronchodilator Agents; Caffeine; Czechoslovaki | 1968 |
Syndrome associated with the abuse of analgesics.
Topics: Adult; Age Factors; Analgesics; Anemia; Animals; Aspirin; Caffeine; Cats; Dogs; Female; Guinea Pigs; | 1968 |
Analgesic abuse: maximal tolerated daily doses of acetylsalicylic acid.
Topics: Acetaminophen; Acids; Analgesics; Animals; Appetite; Aspirin; Brain; Caffeine; Growth; Humans; Phena | 1968 |
Addiction to daprisal.
Topics: Adult; Amobarbital; Analgesics; Aspirin; Depression; Dextroamphetamine; Humans; Phenacetin; Substanc | 1968 |
Gastric ulcer, duodenal ulcer and gastric carcinoma: a case-control study of certain social and environmental factors.
Topics: Adult; Aged; Alcohol Drinking; Aspirin; Australia; Divorce; Duodenal Ulcer; Educational Status; Fami | 1968 |
The occurrence and clinical features of analgesic abuse in Western Scotland.
Topics: Adult; Aged; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Sideroblastic; Aspirin; Blood Urea Nitr | 1968 |
Renal papillary necrosis and aspirin.
Topics: Aspirin; Humans; Kidney Function Tests; Kidney Papillary Necrosis; Male; Middle Aged; Phenacetin; Su | 1969 |
Analgesics: a warning.
Topics: Analgesics; Aspirin; Australia; Child; Drug and Narcotic Control; Drug Labeling; Humans; Substance-R | 1969 |
Statement on analgesic nephropathy.
Topics: Analgesics; Animals; Aspirin; Australia; Caffeine; Drug and Narcotic Control; Drug Labeling; Female; | 1969 |
Renal accumulation of salicylate and phenacetin: possible mechanisms in the nephropathy of analgesic abuse.
Topics: Analgesics; Animals; Aspirin; Dehydration; Dogs; Female; Humans; Hydrogen-Ion Concentration; Kidney; | 1969 |
[Thrombopathy following use of Acetosal].
Topics: Aspirin; Blood Platelet Disorders; Humans; Substance-Related Disorders | 1969 |